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Network neighborhood for query Sequence : TS1R2_MOUSE

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TS1R2_MOUSE
SwissProt Accessions	Q925I4, Q923J8	Gene names	Tas1r2, Gpr71, T1r2, Tr2
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 2 precursor (G-protein coupled receptor 71) (Sweet taste receptor T1R2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

TS1R2_HUMAN
θ value	0 (rank : 1)	NC score	0.995022 (rank : 2)
Query Neighborhood Hits	69	Target Neighborhood Hits	48	Shared Neighborhood Hits	40
SwissProt Accessions	Q8TE23, Q5TZ19	Gene names	TAS1R2, GPR71, T1R2, TR2
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 2 precursor (G-protein coupled receptor 71) (Sweet taste receptor T1R2).

TS1R2_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	69	Target Neighborhood Hits	69	Shared Neighborhood Hits	69
SwissProt Accessions	Q925I4, Q923J8	Gene names	Tas1r2, Gpr71, T1r2, Tr2
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 2 precursor (G-protein coupled receptor 71) (Sweet taste receptor T1R2).

TS1R1_MOUSE
θ value	1.33145e-144 (rank : 3)	NC score	0.978358 (rank : 3)
Query Neighborhood Hits	69	Target Neighborhood Hits	57	Shared Neighborhood Hits	39
SwissProt Accessions	Q99PG6, Q6NS58, Q923J9, Q925I5, Q99PG5	Gene names	Tas1r1, Gpr70, T1r1, Tr1
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 1 precursor (G-protein coupled receptor 70).

TS1R1_HUMAN
θ value	5.78879e-140 (rank : 4)	NC score	0.976777 (rank : 4)
Query Neighborhood Hits	69	Target Neighborhood Hits	72	Shared Neighborhood Hits	37
SwissProt Accessions	Q7RTX1, Q8NGZ7, Q8TDJ7, Q8TDJ8, Q8TDJ9, Q8TDK0	Gene names	TAS1R1, GPR70, T1R1, TR1
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 1 precursor (G-protein coupled receptor 70) (Gm148).

TS1R3_MOUSE
θ value	5.29683e-101 (rank : 5)	NC score	0.966872 (rank : 5)
Query Neighborhood Hits	69	Target Neighborhood Hits	49	Shared Neighborhood Hits	36
SwissProt Accessions	Q925D8, Q91VA4, Q923K0, Q925A4, Q925D9	Gene names	Tas1r3, Sac, T1r3, Tr3
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 3 precursor (Sweet taste receptor T1R3) (Saccharin preference protein).

CASR_HUMAN
θ value	9.98939e-100 (rank : 6)	NC score	0.959596 (rank : 9)
Query Neighborhood Hits	69	Target Neighborhood Hits	71	Shared Neighborhood Hits	38
SwissProt Accessions	P41180, Q13912, Q16108, Q16109, Q16110, Q16379, Q4PJ19	Gene names	CASR, GPRC2A, PCAR1
Domain Architecture
Description	Extracellular calcium-sensing receptor precursor (CaSR) (Parathyroid Cell calcium-sensing receptor).

CASR_MOUSE
θ value	3.21347e-98 (rank : 7)	NC score	0.958680 (rank : 10)
Query Neighborhood Hits	69	Target Neighborhood Hits	72	Shared Neighborhood Hits	39
SwissProt Accessions	Q9QY96, O08968, O88519, Q9QY95, Q9QZU8, Q9R1D6, Q9R1Y2	Gene names	Casr, Gprc2a
Domain Architecture
Description	Extracellular calcium-sensing receptor precursor (CaSR) (Parathyroid Cell calcium-sensing receptor).

GPC6A_MOUSE
θ value	2.30293e-96 (rank : 8)	NC score	0.964126 (rank : 7)
Query Neighborhood Hits	69	Target Neighborhood Hits	57	Shared Neighborhood Hits	38
SwissProt Accessions	Q8K4Z6, Q5DK51, Q5DK52	Gene names	Gprc6a
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor family C group 6 member A precursor.

TS1R3_HUMAN
θ value	5.67233e-95 (rank : 9)	NC score	0.965038 (rank : 6)
Query Neighborhood Hits	69	Target Neighborhood Hits	46	Shared Neighborhood Hits	34
SwissProt Accessions	Q7RTX0, Q5TA49, Q8NGW9	Gene names	TAS1R3, T1R3, TR3
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 3 precursor (Sweet taste receptor T1R3).

GPC6A_HUMAN
θ value	2.91321e-91 (rank : 10)	NC score	0.962805 (rank : 8)
Query Neighborhood Hits	69	Target Neighborhood Hits	53	Shared Neighborhood Hits	39
SwissProt Accessions	Q5T6X5, Q6JK43, Q6JK44, Q8NGU8, Q8NHZ9, Q8TDT6	Gene names	GPRC6A, GPCR33
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor family C group 6 member A precursor (hGPRC6A) (G-protein coupled receptor 33) (hGPCR33).

V2RX_MOUSE
θ value	5.34618e-69 (rank : 11)	NC score	0.953453 (rank : 11)
Query Neighborhood Hits	69	Target Neighborhood Hits	45	Shared Neighborhood Hits	33
SwissProt Accessions	O70410	Gene names
Domain Architecture	No domain graphic available
Description	Vomeronasal type-2 receptor X precursor (Putative pheromone receptor V2RX).

MGR4_HUMAN
θ value	2.74572e-65 (rank : 12)	NC score	0.910035 (rank : 17)
Query Neighborhood Hits	69	Target Neighborhood Hits	63	Shared Neighborhood Hits	40
SwissProt Accessions	Q14833, Q5SZ84	Gene names	GRM4, GPRC1D, MGLUR4
Domain Architecture
Description	Metabotropic glutamate receptor 4 precursor (mGluR4).

MGR3_MOUSE
θ value	4.68348e-65 (rank : 13)	NC score	0.916697 (rank : 14)
Query Neighborhood Hits	69	Target Neighborhood Hits	54	Shared Neighborhood Hits	40
SwissProt Accessions	Q9QYS2	Gene names	Grm3, Gprc1c, Mglur3
Domain Architecture
Description	Metabotropic glutamate receptor 3 precursor (mGluR3).

MGR7_HUMAN
θ value	7.98882e-65 (rank : 14)	NC score	0.905986 (rank : 20)
Query Neighborhood Hits	69	Target Neighborhood Hits	52	Shared Neighborhood Hits	35
SwissProt Accessions	Q14831, Q8NFS2, Q8NFS3, Q8NFS4	Gene names	GRM7, GPRC1G, MGLUR7
Domain Architecture
Description	Metabotropic glutamate receptor 7 precursor (mGluR7).

MGR7_MOUSE
θ value	1.36269e-64 (rank : 15)	NC score	0.905842 (rank : 21)
Query Neighborhood Hits	69	Target Neighborhood Hits	53	Shared Neighborhood Hits	35
SwissProt Accessions	Q68ED2	Gene names	Grm7, Gprc1g, Mglur7
Domain Architecture	No domain graphic available
Description	Metabotropic glutamate receptor 7 precursor (mGluR7).

MGR3_HUMAN
θ value	2.17557e-62 (rank : 16)	NC score	0.916344 (rank : 15)
Query Neighborhood Hits	69	Target Neighborhood Hits	58	Shared Neighborhood Hits	40
SwissProt Accessions	Q14832, Q75MV4, Q75N17, Q86YG6, Q8TBH9	Gene names	GRM3, GPRC1C, MGLUR3
Domain Architecture
Description	Metabotropic glutamate receptor 3 precursor (mGluR3).

MGR6_MOUSE
θ value	2.40537e-61 (rank : 17)	NC score	0.901280 (rank : 25)
Query Neighborhood Hits	69	Target Neighborhood Hits	56	Shared Neighborhood Hits	32
SwissProt Accessions	Q5NCH9	Gene names	Grm6, Gprc1f, Mglur6
Domain Architecture	No domain graphic available
Description	Metabotropic glutamate receptor 6 precursor (mGluR6).

MGR6_HUMAN
θ value	4.53632e-60 (rank : 18)	NC score	0.902072 (rank : 24)
Query Neighborhood Hits	69	Target Neighborhood Hits	58	Shared Neighborhood Hits	34
SwissProt Accessions	O15303	Gene names	GRM6, GPRC1F, MGLUR6
Domain Architecture
Description	Metabotropic glutamate receptor 6 precursor (mGluR6).

MGR2_HUMAN
θ value	1.7238e-59 (rank : 19)	NC score	0.921342 (rank : 13)
Query Neighborhood Hits	69	Target Neighborhood Hits	56	Shared Neighborhood Hits	40
SwissProt Accessions	Q14416, Q52MC6, Q9H3N6	Gene names	GRM2, GPRC1B, MGLUR2
Domain Architecture
Description	Metabotropic glutamate receptor 2 precursor (mGluR2).

MGR8_MOUSE
θ value	1.90589e-58 (rank : 20)	NC score	0.904143 (rank : 22)
Query Neighborhood Hits	69	Target Neighborhood Hits	44	Shared Neighborhood Hits	33
SwissProt Accessions	P47743, Q6B964	Gene names	Grm8, Gprc1h, Mglur8
Domain Architecture
Description	Metabotropic glutamate receptor 8 precursor (mGluR8).

MGR8_HUMAN
θ value	7.24236e-58 (rank : 21)	NC score	0.903572 (rank : 23)
Query Neighborhood Hits	69	Target Neighborhood Hits	49	Shared Neighborhood Hits	33
SwissProt Accessions	O00222, O15493, O95945, O95946, Q3MIV9, Q52M02, Q6J165	Gene names	GRM8, GPRC1H, MGLUR8
Domain Architecture
Description	Metabotropic glutamate receptor 8 precursor (mGluR8).

MGR1_HUMAN
θ value	3.1488e-53 (rank : 22)	NC score	0.908837 (rank : 18)
Query Neighborhood Hits	69	Target Neighborhood Hits	85	Shared Neighborhood Hits	41
SwissProt Accessions	Q13255, Q13256, Q14757, Q14758, Q5VTF7, Q5VTF8, Q9NU10, Q9UGS9, Q9UGT0	Gene names	GRM1, GPRC1A, MGLUR1
Domain Architecture
Description	Metabotropic glutamate receptor 1 precursor (mGluR1).

MGR5_HUMAN
θ value	5.93839e-52 (rank : 23)	NC score	0.910453 (rank : 16)
Query Neighborhood Hits	69	Target Neighborhood Hits	72	Shared Neighborhood Hits	38
SwissProt Accessions	P41594	Gene names	GRM5, GPRC1E, MGLUR5
Domain Architecture
Description	Metabotropic glutamate receptor 5 precursor (mGluR5).

MGR1_MOUSE
θ value	5.02714e-51 (rank : 24)	NC score	0.908324 (rank : 19)
Query Neighborhood Hits	69	Target Neighborhood Hits	90	Shared Neighborhood Hits	41
SwissProt Accessions	P97772, Q6AXG4, Q9EPV6	Gene names	Grm1, Gprc1a, Mglur1
Domain Architecture
Description	Metabotropic glutamate receptor 1 precursor (mGluR1).

V2R1B_MOUSE
θ value	2.59387e-31 (rank : 25)	NC score	0.924723 (rank : 12)
Query Neighborhood Hits	69	Target Neighborhood Hits	39	Shared Neighborhood Hits	27
SwissProt Accessions	Q6TAC4, O70409	Gene names	V2r1b
Domain Architecture	No domain graphic available
Description	Vomeronasal type-2 receptor 1b precursor (Putative pheromone receptor V2R1b).

GABR2_HUMAN
θ value	3.77169e-06 (rank : 26)	NC score	0.518495 (rank : 26)
Query Neighborhood Hits	69	Target Neighborhood Hits	101	Shared Neighborhood Hits	36
SwissProt Accessions	O75899, O75974, O75975, Q5VXZ2, Q8WX04, Q9P1R2, Q9UNR1, Q9UNS9	Gene names	GABBR2, GPR51, GPRC3B
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 2 precursor (GABA-B receptor 2) (GABA-B-R2) (Gb2) (GABABR2) (G-protein coupled receptor 51) (HG20).

NMDZ1_HUMAN
θ value	4.92598e-06 (rank : 27)	NC score	0.217159 (rank : 32)
Query Neighborhood Hits	69	Target Neighborhood Hits	77	Shared Neighborhood Hits	35
SwissProt Accessions	Q05586, P35437, Q12867, Q12868	Gene names	GRIN1, NMDAR1
Domain Architecture
Description	Glutamate [NMDA] receptor subunit zeta 1 precursor (N-methyl-D- aspartate receptor subunit NR1).

NMDZ1_MOUSE
θ value	4.92598e-06 (rank : 28)	NC score	0.217811 (rank : 31)
Query Neighborhood Hits	69	Target Neighborhood Hits	76	Shared Neighborhood Hits	35
SwissProt Accessions	P35438, Q8CFS4	Gene names	Grin1, Glurz1
Domain Architecture
Description	Glutamate [NMDA] receptor subunit zeta 1 precursor (N-methyl-D- aspartate receptor subunit NR1).

GABR1_HUMAN
θ value	9.29e-05 (rank : 29)	NC score	0.414671 (rank : 27)
Query Neighborhood Hits	69	Target Neighborhood Hits	142	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UBS5, O95375, O95468, O95975, O96022, Q86W60, Q9UQQ0	Gene names	GABBR1, GPRC3A
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

GABR1_MOUSE
θ value	9.29e-05 (rank : 30)	NC score	0.414579 (rank : 28)
Query Neighborhood Hits	69	Target Neighborhood Hits	139	Shared Neighborhood Hits	32
SwissProt Accessions	Q9WV18, Q9WU48, Q9WV15, Q9WV16, Q9WV17	Gene names	Gabbr1
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

GRIK2_HUMAN
θ value	0.00228821 (rank : 31)	NC score	0.080628 (rank : 46)
Query Neighborhood Hits	69	Target Neighborhood Hits	50	Shared Neighborhood Hits	19
SwissProt Accessions	Q13002	Gene names	GRIK2, GLUR6
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 2 precursor (Glutamate receptor 6) (GluR-6) (GluR6) (Excitatory amino acid receptor 4) (EAA4).

GPC5C_HUMAN
θ value	0.00298849 (rank : 32)	NC score	0.172580 (rank : 34)
Query Neighborhood Hits	69	Target Neighborhood Hits	26	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NQ84, Q9NZG5	Gene names	GPRC5C, RAIG3
Domain Architecture
Description	G-protein coupled receptor family C group 5 member C precursor (Retinoic acid-induced gene 3 protein) (RAIG-3).

GPC5C_MOUSE
θ value	0.0193708 (rank : 33)	NC score	0.182913 (rank : 33)
Query Neighborhood Hits	69	Target Neighborhood Hits	25	Shared Neighborhood Hits	20
SwissProt Accessions	Q8K3J9, Q8K0H0	Gene names	Gprc5c, Raig3
Domain Architecture
Description	G-protein coupled receptor family C group 5 member C precursor (Retinoic acid-induced gene 3 protein) (RAIG-3).

GRIK1_HUMAN
θ value	0.0252991 (rank : 34)	NC score	0.075905 (rank : 47)
Query Neighborhood Hits	69	Target Neighborhood Hits	48	Shared Neighborhood Hits	18
SwissProt Accessions	P39086, Q13001, Q86SU9	Gene names	GRIK1, GLUR5
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 1 precursor (Glutamate receptor 5) (GluR-5) (GluR5) (Excitatory amino acid receptor 3) (EAA3).

ANPRB_HUMAN
θ value	0.0330416 (rank : 35)	NC score	0.024612 (rank : 54)
Query Neighborhood Hits	69	Target Neighborhood Hits	646	Shared Neighborhood Hits	12
SwissProt Accessions	P20594, O60871, Q9UQ50	Gene names	NPR2, ANPRB
Domain Architecture
Description	Atrial natriuretic peptide receptor B precursor (ANP-B) (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor).

ANPRB_MOUSE
θ value	0.0330416 (rank : 36)	NC score	0.025287 (rank : 53)
Query Neighborhood Hits	69	Target Neighborhood Hits	607	Shared Neighborhood Hits	11
SwissProt Accessions	Q6VVW5, Q6VVW3, Q6VVW4, Q8CGA9	Gene names	Npr2
Domain Architecture	No domain graphic available
Description	Atrial natriuretic peptide receptor B precursor (ANP-B) (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor).

GPC5B_MOUSE
θ value	0.0431538 (rank : 37)	NC score	0.285215 (rank : 29)
Query Neighborhood Hits	69	Target Neighborhood Hits	33	Shared Neighborhood Hits	26
SwissProt Accessions	Q923Z0, Q8CCV3	Gene names	Gprc5b, Raig2
Domain Architecture
Description	G-protein coupled receptor family C group 5 member B precursor (Retinoic acid-induced gene 2 protein) (RAIG-2).

GRIK1_MOUSE
θ value	0.0563607 (rank : 38)	NC score	0.075841 (rank : 48)
Query Neighborhood Hits	69	Target Neighborhood Hits	46	Shared Neighborhood Hits	18
SwissProt Accessions	Q60934	Gene names	Grik1, Glur5
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 1 precursor (Glutamate receptor 5) (GluR-5) (GluR5).

GUC2F_HUMAN
θ value	0.0736092 (rank : 39)	NC score	0.053511 (rank : 49)
Query Neighborhood Hits	69	Target Neighborhood Hits	740	Shared Neighborhood Hits	23
SwissProt Accessions	P51841, Q9UJF1	Gene names	GUCY2F, GUC2F, RETGC2
Domain Architecture
Description	Retinal guanylyl cyclase 2 precursor (EC 4.6.1.2) (Guanylate cyclase 2F, retinal) (RETGC-2) (Rod outer segment membrane guanylate cyclase 2) (ROS-GC2) (Guanylate cyclase F) (GC-F).

ZAN_MOUSE
θ value	0.0961366 (rank : 40)	NC score	0.011863 (rank : 63)
Query Neighborhood Hits	69	Target Neighborhood Hits	808	Shared Neighborhood Hits	8
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

SCUB3_HUMAN
θ value	0.125558 (rank : 41)	NC score	0.016219 (rank : 57)
Query Neighborhood Hits	69	Target Neighborhood Hits	428	Shared Neighborhood Hits	15
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

GPC5D_MOUSE
θ value	0.21417 (rank : 42)	NC score	0.125761 (rank : 37)
Query Neighborhood Hits	69	Target Neighborhood Hits	19	Shared Neighborhood Hits	15
SwissProt Accessions	Q9JIL6, Q8CJI0, Q8CJI1	Gene names	Gprc5d
Domain Architecture
Description	G-protein coupled receptor family C group 5 member D.

GPC5B_HUMAN
θ value	0.279714 (rank : 43)	NC score	0.258789 (rank : 30)
Query Neighborhood Hits	69	Target Neighborhood Hits	28	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NZH0, O75205, Q8NBZ8	Gene names	GPRC5B, RAIG2
Domain Architecture
Description	G-protein coupled receptor family C group 5 member B precursor (Retinoic acid-induced gene 2 protein) (RAIG-2) (A-69G12.1).

SCUB3_MOUSE
θ value	0.47712 (rank : 44)	NC score	0.015761 (rank : 58)
Query Neighborhood Hits	69	Target Neighborhood Hits	442	Shared Neighborhood Hits	14
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

GRIK3_HUMAN
θ value	0.62314 (rank : 45)	NC score	0.051949 (rank : 50)
Query Neighborhood Hits	69	Target Neighborhood Hits	41	Shared Neighborhood Hits	16
SwissProt Accessions	Q13003, Q13004, Q16136	Gene names	GRIK3, GLUR7
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 3 precursor (Glutamate receptor 7) (GluR-7) (GluR7) (Excitatory amino acid receptor 5) (EAA5).

RAI3_MOUSE
θ value	0.813845 (rank : 46)	NC score	0.118886 (rank : 38)
Query Neighborhood Hits	69	Target Neighborhood Hits	20	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BHL4, Q8K067, Q8K1G5	Gene names	Gprc5a, Rai3, Raig1
Domain Architecture
Description	Retinoic acid-induced protein 3 (G-protein coupled receptor family C group 5 member A) (Retinoic acid-induced gene 1 protein) (RAIG-1).

TNR18_MOUSE
θ value	0.813845 (rank : 47)	NC score	0.022053 (rank : 55)
Query Neighborhood Hits	69	Target Neighborhood Hits	36	Shared Neighborhood Hits	4
SwissProt Accessions	O35714, Q9JKR1, Q9JKR2, Q9JKR3	Gene names	Tnfrsf18, Gitr
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 18 precursor (Glucocorticoid-induced TNFR-related protein).

SMOO_HUMAN
θ value	1.06291 (rank : 48)	NC score	0.009599 (rank : 64)
Query Neighborhood Hits	69	Target Neighborhood Hits	391	Shared Neighborhood Hits	3
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

ANPRC_HUMAN
θ value	1.38821 (rank : 49)	NC score	0.102961 (rank : 42)
Query Neighborhood Hits	69	Target Neighborhood Hits	27	Shared Neighborhood Hits	21
SwissProt Accessions	P17342	Gene names	NPR3, ANPRC
Domain Architecture
Description	Atrial natriuretic peptide clearance receptor precursor (ANP-C) (ANPRC) (NPR-C) (Atrial natriuretic peptide C-type receptor).

ANPRC_MOUSE
θ value	1.38821 (rank : 50)	NC score	0.112788 (rank : 39)
Query Neighborhood Hits	69	Target Neighborhood Hits	27	Shared Neighborhood Hits	22
SwissProt Accessions	P70180, P97804, Q9R025, Q9R027, Q9R028	Gene names	Npr3
Domain Architecture
Description	Atrial natriuretic peptide clearance receptor precursor (ANP-C) (ANPRC) (NPR-C) (Atrial natriuretic peptide C-type receptor) (EF-2).

GPC5D_HUMAN
θ value	1.81305 (rank : 51)	NC score	0.103515 (rank : 41)
Query Neighborhood Hits	69	Target Neighborhood Hits	21	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NZD1, Q3KNV3, Q7Z5J9, Q8TDS6	Gene names	GPRC5D
Domain Architecture
Description	G-protein coupled receptor family C group 5 member D.

PCSK5_MOUSE
θ value	1.81305 (rank : 52)	NC score	0.007073 (rank : 67)
Query Neighborhood Hits	69	Target Neighborhood Hits	613	Shared Neighborhood Hits	10
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

EPHA1_HUMAN
θ value	2.36792 (rank : 53)	NC score	0.003372 (rank : 69)
Query Neighborhood Hits	69	Target Neighborhood Hits	997	Shared Neighborhood Hits	14
SwissProt Accessions	P21709, Q15405	Gene names	EPHA1, EPH, EPHT, EPHT1
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH).

NUPL_HUMAN
θ value	2.36792 (rank : 54)	NC score	0.014543 (rank : 59)
Query Neighborhood Hits	69	Target Neighborhood Hits	68	Shared Neighborhood Hits	3
SwissProt Accessions	P52594, Q15277, Q4VAS0, Q4VAS1, Q4VAS3, Q53QT8, Q53R11	Gene names	HRB, RAB, RIP
Domain Architecture
Description	Nucleoporin-like protein RIP (HIV-1 Rev-binding protein) (Rev- interacting protein) (Rev/Rex activation domain-binding protein).

NUPL_MOUSE
θ value	2.36792 (rank : 55)	NC score	0.014308 (rank : 60)
Query Neighborhood Hits	69	Target Neighborhood Hits	113	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K2K6, O70448, Q8BQL5, Q8CDK9	Gene names	Hrb, Rip
Domain Architecture
Description	Nucleoporin-like protein RIP (HIV-1 Rev-binding protein homolog).

SL9A9_MOUSE
θ value	2.36792 (rank : 56)	NC score	0.007516 (rank : 66)
Query Neighborhood Hits	69	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BZ00, Q3U0X0	Gene names	Slc9a9, Nhe9
Domain Architecture
Description	Sodium/hydrogen exchanger 9 (Na(+)/H(+) exchanger 9) (NHE-9) (Solute carrier family 9 member 9).

TNR14_HUMAN
θ value	2.36792 (rank : 57)	NC score	0.012222 (rank : 62)
Query Neighborhood Hits	69	Target Neighborhood Hits	149	Shared Neighborhood Hits	9
SwissProt Accessions	Q92956, Q8WXR1, Q96J31, Q9UM65	Gene names	TNFRSF14, HVEA, HVEM
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 14 precursor (Herpesvirus entry mediator A) (Tumor necrosis factor receptor-like 2) (TR2).

GRIA4_HUMAN
θ value	3.0926 (rank : 58)	NC score	0.035096 (rank : 52)
Query Neighborhood Hits	69	Target Neighborhood Hits	45	Shared Neighborhood Hits	9
SwissProt Accessions	P48058	Gene names	GRIA4, GLUR4
Domain Architecture
Description	Glutamate receptor 4 precursor (GluR-4) (GluR4) (GluR-D) (Glutamate receptor ionotropic, AMPA 4) (AMPA-selective glutamate receptor 4).

GRIA4_MOUSE
θ value	3.0926 (rank : 59)	NC score	0.035133 (rank : 51)
Query Neighborhood Hits	69	Target Neighborhood Hits	44	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Z2W8	Gene names	Gria4, Glur4
Domain Architecture
Description	Glutamate receptor 4 precursor (GluR-4) (GluR4) (GluR-D) (Glutamate receptor ionotropic, AMPA 4) (AMPA-selective glutamate receptor 4).

NU6M_HUMAN
θ value	3.0926 (rank : 60)	NC score	0.018176 (rank : 56)
Query Neighborhood Hits	69	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	P03923, Q34774, Q8HG30	Gene names	MT-ND6, MTND6, NADH6, ND6
Domain Architecture
Description	NADH-ubiquinone oxidoreductase chain 6 (EC 1.6.5.3) (NADH dehydrogenase subunit 6).

TRI65_MOUSE
θ value	4.03905 (rank : 61)	NC score	0.002449 (rank : 72)
Query Neighborhood Hits	69	Target Neighborhood Hits	340	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BFW4, Q6PGD3	Gene names	Trim65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

PDRG1_HUMAN
θ value	5.27518 (rank : 62)	NC score	0.013859 (rank : 61)
Query Neighborhood Hits	69	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NUG6, Q96GP3, Q9BUW8	Gene names	PDRG1, C20orf126, PDRG
Domain Architecture	No domain graphic available
Description	p53 and DNA damage-regulated protein 1.

ABCAD_HUMAN
θ value	6.88961 (rank : 63)	NC score	0.001721 (rank : 73)
Query Neighborhood Hits	69	Target Neighborhood Hits	207	Shared Neighborhood Hits	2
SwissProt Accessions	Q86UQ4, Q6ZTT7, Q86WI2, Q8N248	Gene names	ABCA13
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 13.

ELTD1_HUMAN
θ value	6.88961 (rank : 64)	NC score	0.001619 (rank : 74)
Query Neighborhood Hits	69	Target Neighborhood Hits	269	Shared Neighborhood Hits	5
SwissProt Accessions	Q9HBW9	Gene names	ELTD1, ETL
Domain Architecture
Description	EGF, latrophilin and seven transmembrane domain-containing protein 1 precursor (EGF-TM7-latrophilin-related protein) (ETL protein).

NPAL1_HUMAN
θ value	6.88961 (rank : 65)	NC score	0.005906 (rank : 68)
Query Neighborhood Hits	69	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q6NVV3, Q68DA9	Gene names	NPAL1
Domain Architecture	No domain graphic available
Description	NIPA-like protein 1.

TNR1B_MOUSE
θ value	6.88961 (rank : 66)	NC score	0.007744 (rank : 65)
Query Neighborhood Hits	69	Target Neighborhood Hits	123	Shared Neighborhood Hits	9
SwissProt Accessions	P25119, O88734, P97893	Gene names	Tnfrsf1b, Tnfr-2, Tnfr2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor).

GP179_HUMAN
θ value	8.99809 (rank : 67)	NC score	0.104246 (rank : 40)
Query Neighborhood Hits	69	Target Neighborhood Hits	372	Shared Neighborhood Hits	13
SwissProt Accessions	Q6PRD1	Gene names	GPR179, GPR158L1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 179 precursor (Probable G-protein coupled receptor 158-like 1).

PCOC2_HUMAN
θ value	8.99809 (rank : 68)	NC score	0.003227 (rank : 70)
Query Neighborhood Hits	69	Target Neighborhood Hits	73	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UKZ9, Q9BRH3	Gene names	PCOLCE2, PCPE2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

S12A2_MOUSE
θ value	8.99809 (rank : 69)	NC score	0.002577 (rank : 71)
Query Neighborhood Hits	69	Target Neighborhood Hits	55	Shared Neighborhood Hits	2
SwissProt Accessions	P55012	Gene names	Slc12a2, Nkcc1
Domain Architecture
Description	Solute carrier family 12 member 2 (Bumetanide-sensitive sodium- (potassium)-chloride cotransporter 1) (Basolateral Na-K-Cl symporter).

GP156_HUMAN
θ value	θ > 10 (rank : 70)	NC score	0.081661 (rank : 45)
Query Neighborhood Hits	69	Target Neighborhood Hits	84	Shared Neighborhood Hits	11
SwissProt Accessions	Q8NFN8, Q86SN6	Gene names	GPR156, GABABL, PGR28
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 156 (GABAB-related G-protein coupled receptor) (G-protein coupled receptor PGR28).

GP156_MOUSE
θ value	θ > 10 (rank : 71)	NC score	0.096276 (rank : 43)
Query Neighborhood Hits	69	Target Neighborhood Hits	95	Shared Neighborhood Hits	12
SwissProt Accessions	Q6PCP7, Q8K452	Gene names	Gpr156, Gababl
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 156 (GABAB-related G-protein coupled receptor).

GP158_HUMAN
θ value	θ > 10 (rank : 72)	NC score	0.146434 (rank : 35)
Query Neighborhood Hits	69	Target Neighborhood Hits	221	Shared Neighborhood Hits	19
SwissProt Accessions	Q5T848, Q6QR81, Q9ULT3	Gene names	GPR158, KIAA1136
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 158 precursor.

GP158_MOUSE
θ value	θ > 10 (rank : 73)	NC score	0.129778 (rank : 36)
Query Neighborhood Hits	69	Target Neighborhood Hits	82	Shared Neighborhood Hits	15
SwissProt Accessions	Q8C419, Q8CHB0	Gene names	Gpr158, Kiaa1136
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 158 precursor.

RAI3_HUMAN
θ value	θ > 10 (rank : 74)	NC score	0.089983 (rank : 44)
Query Neighborhood Hits	69	Target Neighborhood Hits	17	Shared Neighborhood Hits	12
SwissProt Accessions	Q8NFJ5, O95357	Gene names	GPRC5A, RAI3, RAIG1
Domain Architecture
Description	Retinoic acid-induced protein 3 (G-protein coupled receptor family C group 5 member A) (Retinoic acid-induced gene 1 protein) (RAIG-1) (Orphan G-protein coupling receptor PEIG-1).

Hits sorted by NC score

TS1R2_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	69	Target Neighborhood Hits	69	Shared Neighborhood Hits	69
SwissProt Accessions	Q925I4, Q923J8	Gene names	Tas1r2, Gpr71, T1r2, Tr2
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 2 precursor (G-protein coupled receptor 71) (Sweet taste receptor T1R2).

TS1R2_HUMAN
NC score	0.995022 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	69	Target Neighborhood Hits	48	Shared Neighborhood Hits	40
SwissProt Accessions	Q8TE23, Q5TZ19	Gene names	TAS1R2, GPR71, T1R2, TR2
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 2 precursor (G-protein coupled receptor 71) (Sweet taste receptor T1R2).

TS1R1_MOUSE
NC score	0.978358 (rank : 3)	θ value	1.33145e-144 (rank : 3)
Query Neighborhood Hits	69	Target Neighborhood Hits	57	Shared Neighborhood Hits	39
SwissProt Accessions	Q99PG6, Q6NS58, Q923J9, Q925I5, Q99PG5	Gene names	Tas1r1, Gpr70, T1r1, Tr1
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 1 precursor (G-protein coupled receptor 70).

TS1R1_HUMAN
NC score	0.976777 (rank : 4)	θ value	5.78879e-140 (rank : 4)
Query Neighborhood Hits	69	Target Neighborhood Hits	72	Shared Neighborhood Hits	37
SwissProt Accessions	Q7RTX1, Q8NGZ7, Q8TDJ7, Q8TDJ8, Q8TDJ9, Q8TDK0	Gene names	TAS1R1, GPR70, T1R1, TR1
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 1 precursor (G-protein coupled receptor 70) (Gm148).

TS1R3_MOUSE
NC score	0.966872 (rank : 5)	θ value	5.29683e-101 (rank : 5)
Query Neighborhood Hits	69	Target Neighborhood Hits	49	Shared Neighborhood Hits	36
SwissProt Accessions	Q925D8, Q91VA4, Q923K0, Q925A4, Q925D9	Gene names	Tas1r3, Sac, T1r3, Tr3
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 3 precursor (Sweet taste receptor T1R3) (Saccharin preference protein).

TS1R3_HUMAN
NC score	0.965038 (rank : 6)	θ value	5.67233e-95 (rank : 9)
Query Neighborhood Hits	69	Target Neighborhood Hits	46	Shared Neighborhood Hits	34
SwissProt Accessions	Q7RTX0, Q5TA49, Q8NGW9	Gene names	TAS1R3, T1R3, TR3
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 3 precursor (Sweet taste receptor T1R3).

GPC6A_MOUSE
NC score	0.964126 (rank : 7)	θ value	2.30293e-96 (rank : 8)
Query Neighborhood Hits	69	Target Neighborhood Hits	57	Shared Neighborhood Hits	38
SwissProt Accessions	Q8K4Z6, Q5DK51, Q5DK52	Gene names	Gprc6a
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor family C group 6 member A precursor.

GPC6A_HUMAN
NC score	0.962805 (rank : 8)	θ value	2.91321e-91 (rank : 10)
Query Neighborhood Hits	69	Target Neighborhood Hits	53	Shared Neighborhood Hits	39
SwissProt Accessions	Q5T6X5, Q6JK43, Q6JK44, Q8NGU8, Q8NHZ9, Q8TDT6	Gene names	GPRC6A, GPCR33
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor family C group 6 member A precursor (hGPRC6A) (G-protein coupled receptor 33) (hGPCR33).

CASR_HUMAN
NC score	0.959596 (rank : 9)	θ value	9.98939e-100 (rank : 6)
Query Neighborhood Hits	69	Target Neighborhood Hits	71	Shared Neighborhood Hits	38
SwissProt Accessions	P41180, Q13912, Q16108, Q16109, Q16110, Q16379, Q4PJ19	Gene names	CASR, GPRC2A, PCAR1
Domain Architecture
Description	Extracellular calcium-sensing receptor precursor (CaSR) (Parathyroid Cell calcium-sensing receptor).

CASR_MOUSE
NC score	0.958680 (rank : 10)	θ value	3.21347e-98 (rank : 7)
Query Neighborhood Hits	69	Target Neighborhood Hits	72	Shared Neighborhood Hits	39
SwissProt Accessions	Q9QY96, O08968, O88519, Q9QY95, Q9QZU8, Q9R1D6, Q9R1Y2	Gene names	Casr, Gprc2a
Domain Architecture
Description	Extracellular calcium-sensing receptor precursor (CaSR) (Parathyroid Cell calcium-sensing receptor).

V2RX_MOUSE
NC score	0.953453 (rank : 11)	θ value	5.34618e-69 (rank : 11)
Query Neighborhood Hits	69	Target Neighborhood Hits	45	Shared Neighborhood Hits	33
SwissProt Accessions	O70410	Gene names
Domain Architecture	No domain graphic available
Description	Vomeronasal type-2 receptor X precursor (Putative pheromone receptor V2RX).

V2R1B_MOUSE
NC score	0.924723 (rank : 12)	θ value	2.59387e-31 (rank : 25)
Query Neighborhood Hits	69	Target Neighborhood Hits	39	Shared Neighborhood Hits	27
SwissProt Accessions	Q6TAC4, O70409	Gene names	V2r1b
Domain Architecture	No domain graphic available
Description	Vomeronasal type-2 receptor 1b precursor (Putative pheromone receptor V2R1b).

MGR2_HUMAN
NC score	0.921342 (rank : 13)	θ value	1.7238e-59 (rank : 19)
Query Neighborhood Hits	69	Target Neighborhood Hits	56	Shared Neighborhood Hits	40
SwissProt Accessions	Q14416, Q52MC6, Q9H3N6	Gene names	GRM2, GPRC1B, MGLUR2
Domain Architecture
Description	Metabotropic glutamate receptor 2 precursor (mGluR2).

MGR3_MOUSE
NC score	0.916697 (rank : 14)	θ value	4.68348e-65 (rank : 13)
Query Neighborhood Hits	69	Target Neighborhood Hits	54	Shared Neighborhood Hits	40
SwissProt Accessions	Q9QYS2	Gene names	Grm3, Gprc1c, Mglur3
Domain Architecture
Description	Metabotropic glutamate receptor 3 precursor (mGluR3).

MGR3_HUMAN
NC score	0.916344 (rank : 15)	θ value	2.17557e-62 (rank : 16)
Query Neighborhood Hits	69	Target Neighborhood Hits	58	Shared Neighborhood Hits	40
SwissProt Accessions	Q14832, Q75MV4, Q75N17, Q86YG6, Q8TBH9	Gene names	GRM3, GPRC1C, MGLUR3
Domain Architecture
Description	Metabotropic glutamate receptor 3 precursor (mGluR3).

MGR5_HUMAN
NC score	0.910453 (rank : 16)	θ value	5.93839e-52 (rank : 23)
Query Neighborhood Hits	69	Target Neighborhood Hits	72	Shared Neighborhood Hits	38
SwissProt Accessions	P41594	Gene names	GRM5, GPRC1E, MGLUR5
Domain Architecture
Description	Metabotropic glutamate receptor 5 precursor (mGluR5).

MGR4_HUMAN
NC score	0.910035 (rank : 17)	θ value	2.74572e-65 (rank : 12)
Query Neighborhood Hits	69	Target Neighborhood Hits	63	Shared Neighborhood Hits	40
SwissProt Accessions	Q14833, Q5SZ84	Gene names	GRM4, GPRC1D, MGLUR4
Domain Architecture
Description	Metabotropic glutamate receptor 4 precursor (mGluR4).

MGR1_HUMAN
NC score	0.908837 (rank : 18)	θ value	3.1488e-53 (rank : 22)
Query Neighborhood Hits	69	Target Neighborhood Hits	85	Shared Neighborhood Hits	41
SwissProt Accessions	Q13255, Q13256, Q14757, Q14758, Q5VTF7, Q5VTF8, Q9NU10, Q9UGS9, Q9UGT0	Gene names	GRM1, GPRC1A, MGLUR1
Domain Architecture
Description	Metabotropic glutamate receptor 1 precursor (mGluR1).

MGR1_MOUSE
NC score	0.908324 (rank : 19)	θ value	5.02714e-51 (rank : 24)
Query Neighborhood Hits	69	Target Neighborhood Hits	90	Shared Neighborhood Hits	41
SwissProt Accessions	P97772, Q6AXG4, Q9EPV6	Gene names	Grm1, Gprc1a, Mglur1
Domain Architecture
Description	Metabotropic glutamate receptor 1 precursor (mGluR1).

MGR7_HUMAN
NC score	0.905986 (rank : 20)	θ value	7.98882e-65 (rank : 14)
Query Neighborhood Hits	69	Target Neighborhood Hits	52	Shared Neighborhood Hits	35
SwissProt Accessions	Q14831, Q8NFS2, Q8NFS3, Q8NFS4	Gene names	GRM7, GPRC1G, MGLUR7
Domain Architecture
Description	Metabotropic glutamate receptor 7 precursor (mGluR7).

MGR7_MOUSE
NC score	0.905842 (rank : 21)	θ value	1.36269e-64 (rank : 15)
Query Neighborhood Hits	69	Target Neighborhood Hits	53	Shared Neighborhood Hits	35
SwissProt Accessions	Q68ED2	Gene names	Grm7, Gprc1g, Mglur7
Domain Architecture	No domain graphic available
Description	Metabotropic glutamate receptor 7 precursor (mGluR7).

MGR8_MOUSE
NC score	0.904143 (rank : 22)	θ value	1.90589e-58 (rank : 20)
Query Neighborhood Hits	69	Target Neighborhood Hits	44	Shared Neighborhood Hits	33
SwissProt Accessions	P47743, Q6B964	Gene names	Grm8, Gprc1h, Mglur8
Domain Architecture
Description	Metabotropic glutamate receptor 8 precursor (mGluR8).

MGR8_HUMAN
NC score	0.903572 (rank : 23)	θ value	7.24236e-58 (rank : 21)
Query Neighborhood Hits	69	Target Neighborhood Hits	49	Shared Neighborhood Hits	33
SwissProt Accessions	O00222, O15493, O95945, O95946, Q3MIV9, Q52M02, Q6J165	Gene names	GRM8, GPRC1H, MGLUR8
Domain Architecture
Description	Metabotropic glutamate receptor 8 precursor (mGluR8).

MGR6_HUMAN
NC score	0.902072 (rank : 24)	θ value	4.53632e-60 (rank : 18)
Query Neighborhood Hits	69	Target Neighborhood Hits	58	Shared Neighborhood Hits	34
SwissProt Accessions	O15303	Gene names	GRM6, GPRC1F, MGLUR6
Domain Architecture
Description	Metabotropic glutamate receptor 6 precursor (mGluR6).

MGR6_MOUSE
NC score	0.901280 (rank : 25)	θ value	2.40537e-61 (rank : 17)
Query Neighborhood Hits	69	Target Neighborhood Hits	56	Shared Neighborhood Hits	32
SwissProt Accessions	Q5NCH9	Gene names	Grm6, Gprc1f, Mglur6
Domain Architecture	No domain graphic available
Description	Metabotropic glutamate receptor 6 precursor (mGluR6).

GABR2_HUMAN
NC score	0.518495 (rank : 26)	θ value	3.77169e-06 (rank : 26)
Query Neighborhood Hits	69	Target Neighborhood Hits	101	Shared Neighborhood Hits	36
SwissProt Accessions	O75899, O75974, O75975, Q5VXZ2, Q8WX04, Q9P1R2, Q9UNR1, Q9UNS9	Gene names	GABBR2, GPR51, GPRC3B
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 2 precursor (GABA-B receptor 2) (GABA-B-R2) (Gb2) (GABABR2) (G-protein coupled receptor 51) (HG20).

GABR1_HUMAN
NC score	0.414671 (rank : 27)	θ value	9.29e-05 (rank : 29)
Query Neighborhood Hits	69	Target Neighborhood Hits	142	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UBS5, O95375, O95468, O95975, O96022, Q86W60, Q9UQQ0	Gene names	GABBR1, GPRC3A
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

GABR1_MOUSE
NC score	0.414579 (rank : 28)	θ value	9.29e-05 (rank : 30)
Query Neighborhood Hits	69	Target Neighborhood Hits	139	Shared Neighborhood Hits	32
SwissProt Accessions	Q9WV18, Q9WU48, Q9WV15, Q9WV16, Q9WV17	Gene names	Gabbr1
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

GPC5B_MOUSE
NC score	0.285215 (rank : 29)	θ value	0.0431538 (rank : 37)
Query Neighborhood Hits	69	Target Neighborhood Hits	33	Shared Neighborhood Hits	26
SwissProt Accessions	Q923Z0, Q8CCV3	Gene names	Gprc5b, Raig2
Domain Architecture
Description	G-protein coupled receptor family C group 5 member B precursor (Retinoic acid-induced gene 2 protein) (RAIG-2).

GPC5B_HUMAN
NC score	0.258789 (rank : 30)	θ value	0.279714 (rank : 43)
Query Neighborhood Hits	69	Target Neighborhood Hits	28	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NZH0, O75205, Q8NBZ8	Gene names	GPRC5B, RAIG2
Domain Architecture
Description	G-protein coupled receptor family C group 5 member B precursor (Retinoic acid-induced gene 2 protein) (RAIG-2) (A-69G12.1).

NMDZ1_MOUSE
NC score	0.217811 (rank : 31)	θ value	4.92598e-06 (rank : 28)
Query Neighborhood Hits	69	Target Neighborhood Hits	76	Shared Neighborhood Hits	35
SwissProt Accessions	P35438, Q8CFS4	Gene names	Grin1, Glurz1
Domain Architecture
Description	Glutamate [NMDA] receptor subunit zeta 1 precursor (N-methyl-D- aspartate receptor subunit NR1).

NMDZ1_HUMAN
NC score	0.217159 (rank : 32)	θ value	4.92598e-06 (rank : 27)
Query Neighborhood Hits	69	Target Neighborhood Hits	77	Shared Neighborhood Hits	35
SwissProt Accessions	Q05586, P35437, Q12867, Q12868	Gene names	GRIN1, NMDAR1
Domain Architecture
Description	Glutamate [NMDA] receptor subunit zeta 1 precursor (N-methyl-D- aspartate receptor subunit NR1).

GPC5C_MOUSE
NC score	0.182913 (rank : 33)	θ value	0.0193708 (rank : 33)
Query Neighborhood Hits	69	Target Neighborhood Hits	25	Shared Neighborhood Hits	20
SwissProt Accessions	Q8K3J9, Q8K0H0	Gene names	Gprc5c, Raig3
Domain Architecture
Description	G-protein coupled receptor family C group 5 member C precursor (Retinoic acid-induced gene 3 protein) (RAIG-3).

GPC5C_HUMAN
NC score	0.172580 (rank : 34)	θ value	0.00298849 (rank : 32)
Query Neighborhood Hits	69	Target Neighborhood Hits	26	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NQ84, Q9NZG5	Gene names	GPRC5C, RAIG3
Domain Architecture
Description	G-protein coupled receptor family C group 5 member C precursor (Retinoic acid-induced gene 3 protein) (RAIG-3).

GP158_HUMAN
NC score	0.146434 (rank : 35)	θ value	θ > 10 (rank : 72)
Query Neighborhood Hits	69	Target Neighborhood Hits	221	Shared Neighborhood Hits	19
SwissProt Accessions	Q5T848, Q6QR81, Q9ULT3	Gene names	GPR158, KIAA1136
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 158 precursor.

GP158_MOUSE
NC score	0.129778 (rank : 36)	θ value	θ > 10 (rank : 73)
Query Neighborhood Hits	69	Target Neighborhood Hits	82	Shared Neighborhood Hits	15
SwissProt Accessions	Q8C419, Q8CHB0	Gene names	Gpr158, Kiaa1136
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 158 precursor.

GPC5D_MOUSE
NC score	0.125761 (rank : 37)	θ value	0.21417 (rank : 42)
Query Neighborhood Hits	69	Target Neighborhood Hits	19	Shared Neighborhood Hits	15
SwissProt Accessions	Q9JIL6, Q8CJI0, Q8CJI1	Gene names	Gprc5d
Domain Architecture
Description	G-protein coupled receptor family C group 5 member D.

RAI3_MOUSE
NC score	0.118886 (rank : 38)	θ value	0.813845 (rank : 46)
Query Neighborhood Hits	69	Target Neighborhood Hits	20	Shared Neighborhood Hits	15
SwissProt Accessions	Q8BHL4, Q8K067, Q8K1G5	Gene names	Gprc5a, Rai3, Raig1
Domain Architecture
Description	Retinoic acid-induced protein 3 (G-protein coupled receptor family C group 5 member A) (Retinoic acid-induced gene 1 protein) (RAIG-1).

ANPRC_MOUSE
NC score	0.112788 (rank : 39)	θ value	1.38821 (rank : 50)
Query Neighborhood Hits	69	Target Neighborhood Hits	27	Shared Neighborhood Hits	22
SwissProt Accessions	P70180, P97804, Q9R025, Q9R027, Q9R028	Gene names	Npr3
Domain Architecture
Description	Atrial natriuretic peptide clearance receptor precursor (ANP-C) (ANPRC) (NPR-C) (Atrial natriuretic peptide C-type receptor) (EF-2).

GP179_HUMAN
NC score	0.104246 (rank : 40)	θ value	8.99809 (rank : 67)
Query Neighborhood Hits	69	Target Neighborhood Hits	372	Shared Neighborhood Hits	13
SwissProt Accessions	Q6PRD1	Gene names	GPR179, GPR158L1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 179 precursor (Probable G-protein coupled receptor 158-like 1).

GPC5D_HUMAN
NC score	0.103515 (rank : 41)	θ value	1.81305 (rank : 51)
Query Neighborhood Hits	69	Target Neighborhood Hits	21	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NZD1, Q3KNV3, Q7Z5J9, Q8TDS6	Gene names	GPRC5D
Domain Architecture
Description	G-protein coupled receptor family C group 5 member D.

ANPRC_HUMAN
NC score	0.102961 (rank : 42)	θ value	1.38821 (rank : 49)
Query Neighborhood Hits	69	Target Neighborhood Hits	27	Shared Neighborhood Hits	21
SwissProt Accessions	P17342	Gene names	NPR3, ANPRC
Domain Architecture
Description	Atrial natriuretic peptide clearance receptor precursor (ANP-C) (ANPRC) (NPR-C) (Atrial natriuretic peptide C-type receptor).

GP156_MOUSE
NC score	0.096276 (rank : 43)	θ value	θ > 10 (rank : 71)
Query Neighborhood Hits	69	Target Neighborhood Hits	95	Shared Neighborhood Hits	12
SwissProt Accessions	Q6PCP7, Q8K452	Gene names	Gpr156, Gababl
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 156 (GABAB-related G-protein coupled receptor).

RAI3_HUMAN
NC score	0.089983 (rank : 44)	θ value	θ > 10 (rank : 74)
Query Neighborhood Hits	69	Target Neighborhood Hits	17	Shared Neighborhood Hits	12
SwissProt Accessions	Q8NFJ5, O95357	Gene names	GPRC5A, RAI3, RAIG1
Domain Architecture
Description	Retinoic acid-induced protein 3 (G-protein coupled receptor family C group 5 member A) (Retinoic acid-induced gene 1 protein) (RAIG-1) (Orphan G-protein coupling receptor PEIG-1).

GP156_HUMAN
NC score	0.081661 (rank : 45)	θ value	θ > 10 (rank : 70)
Query Neighborhood Hits	69	Target Neighborhood Hits	84	Shared Neighborhood Hits	11
SwissProt Accessions	Q8NFN8, Q86SN6	Gene names	GPR156, GABABL, PGR28
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 156 (GABAB-related G-protein coupled receptor) (G-protein coupled receptor PGR28).

GRIK2_HUMAN
NC score	0.080628 (rank : 46)	θ value	0.00228821 (rank : 31)
Query Neighborhood Hits	69	Target Neighborhood Hits	50	Shared Neighborhood Hits	19
SwissProt Accessions	Q13002	Gene names	GRIK2, GLUR6
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 2 precursor (Glutamate receptor 6) (GluR-6) (GluR6) (Excitatory amino acid receptor 4) (EAA4).

GRIK1_HUMAN
NC score	0.075905 (rank : 47)	θ value	0.0252991 (rank : 34)
Query Neighborhood Hits	69	Target Neighborhood Hits	48	Shared Neighborhood Hits	18
SwissProt Accessions	P39086, Q13001, Q86SU9	Gene names	GRIK1, GLUR5
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 1 precursor (Glutamate receptor 5) (GluR-5) (GluR5) (Excitatory amino acid receptor 3) (EAA3).

GRIK1_MOUSE
NC score	0.075841 (rank : 48)	θ value	0.0563607 (rank : 38)
Query Neighborhood Hits	69	Target Neighborhood Hits	46	Shared Neighborhood Hits	18
SwissProt Accessions	Q60934	Gene names	Grik1, Glur5
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 1 precursor (Glutamate receptor 5) (GluR-5) (GluR5).

GUC2F_HUMAN
NC score	0.053511 (rank : 49)	θ value	0.0736092 (rank : 39)
Query Neighborhood Hits	69	Target Neighborhood Hits	740	Shared Neighborhood Hits	23
SwissProt Accessions	P51841, Q9UJF1	Gene names	GUCY2F, GUC2F, RETGC2
Domain Architecture
Description	Retinal guanylyl cyclase 2 precursor (EC 4.6.1.2) (Guanylate cyclase 2F, retinal) (RETGC-2) (Rod outer segment membrane guanylate cyclase 2) (ROS-GC2) (Guanylate cyclase F) (GC-F).

GRIK3_HUMAN
NC score	0.051949 (rank : 50)	θ value	0.62314 (rank : 45)
Query Neighborhood Hits	69	Target Neighborhood Hits	41	Shared Neighborhood Hits	16
SwissProt Accessions	Q13003, Q13004, Q16136	Gene names	GRIK3, GLUR7
Domain Architecture
Description	Glutamate receptor, ionotropic kainate 3 precursor (Glutamate receptor 7) (GluR-7) (GluR7) (Excitatory amino acid receptor 5) (EAA5).

GRIA4_MOUSE
NC score	0.035133 (rank : 51)	θ value	3.0926 (rank : 59)
Query Neighborhood Hits	69	Target Neighborhood Hits	44	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Z2W8	Gene names	Gria4, Glur4
Domain Architecture
Description	Glutamate receptor 4 precursor (GluR-4) (GluR4) (GluR-D) (Glutamate receptor ionotropic, AMPA 4) (AMPA-selective glutamate receptor 4).

GRIA4_HUMAN
NC score	0.035096 (rank : 52)	θ value	3.0926 (rank : 58)
Query Neighborhood Hits	69	Target Neighborhood Hits	45	Shared Neighborhood Hits	9
SwissProt Accessions	P48058	Gene names	GRIA4, GLUR4
Domain Architecture
Description	Glutamate receptor 4 precursor (GluR-4) (GluR4) (GluR-D) (Glutamate receptor ionotropic, AMPA 4) (AMPA-selective glutamate receptor 4).

ANPRB_MOUSE
NC score	0.025287 (rank : 53)	θ value	0.0330416 (rank : 36)
Query Neighborhood Hits	69	Target Neighborhood Hits	607	Shared Neighborhood Hits	11
SwissProt Accessions	Q6VVW5, Q6VVW3, Q6VVW4, Q8CGA9	Gene names	Npr2
Domain Architecture	No domain graphic available
Description	Atrial natriuretic peptide receptor B precursor (ANP-B) (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor).

ANPRB_HUMAN
NC score	0.024612 (rank : 54)	θ value	0.0330416 (rank : 35)
Query Neighborhood Hits	69	Target Neighborhood Hits	646	Shared Neighborhood Hits	12
SwissProt Accessions	P20594, O60871, Q9UQ50	Gene names	NPR2, ANPRB
Domain Architecture
Description	Atrial natriuretic peptide receptor B precursor (ANP-B) (ANPRB) (GC-B) (Guanylate cyclase B) (EC 4.6.1.2) (NPR-B) (Atrial natriuretic peptide B-type receptor).

TNR18_MOUSE
NC score	0.022053 (rank : 55)	θ value	0.813845 (rank : 47)
Query Neighborhood Hits	69	Target Neighborhood Hits	36	Shared Neighborhood Hits	4
SwissProt Accessions	O35714, Q9JKR1, Q9JKR2, Q9JKR3	Gene names	Tnfrsf18, Gitr
Domain Architecture	No domain graphic available
Description	Tumor necrosis factor receptor superfamily member 18 precursor (Glucocorticoid-induced TNFR-related protein).

NU6M_HUMAN
NC score	0.018176 (rank : 56)	θ value	3.0926 (rank : 60)
Query Neighborhood Hits	69	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	P03923, Q34774, Q8HG30	Gene names	MT-ND6, MTND6, NADH6, ND6
Domain Architecture
Description	NADH-ubiquinone oxidoreductase chain 6 (EC 1.6.5.3) (NADH dehydrogenase subunit 6).

SCUB3_HUMAN
NC score	0.016219 (rank : 57)	θ value	0.125558 (rank : 41)
Query Neighborhood Hits	69	Target Neighborhood Hits	428	Shared Neighborhood Hits	15
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SCUB3_MOUSE
NC score	0.015761 (rank : 58)	θ value	0.47712 (rank : 44)
Query Neighborhood Hits	69	Target Neighborhood Hits	442	Shared Neighborhood Hits	14
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

NUPL_HUMAN
NC score	0.014543 (rank : 59)	θ value	2.36792 (rank : 54)
Query Neighborhood Hits	69	Target Neighborhood Hits	68	Shared Neighborhood Hits	3
SwissProt Accessions	P52594, Q15277, Q4VAS0, Q4VAS1, Q4VAS3, Q53QT8, Q53R11	Gene names	HRB, RAB, RIP
Domain Architecture
Description	Nucleoporin-like protein RIP (HIV-1 Rev-binding protein) (Rev- interacting protein) (Rev/Rex activation domain-binding protein).

NUPL_MOUSE
NC score	0.014308 (rank : 60)	θ value	2.36792 (rank : 55)
Query Neighborhood Hits	69	Target Neighborhood Hits	113	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K2K6, O70448, Q8BQL5, Q8CDK9	Gene names	Hrb, Rip
Domain Architecture
Description	Nucleoporin-like protein RIP (HIV-1 Rev-binding protein homolog).

PDRG1_HUMAN
NC score	0.013859 (rank : 61)	θ value	5.27518 (rank : 62)
Query Neighborhood Hits	69	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NUG6, Q96GP3, Q9BUW8	Gene names	PDRG1, C20orf126, PDRG
Domain Architecture	No domain graphic available
Description	p53 and DNA damage-regulated protein 1.

TNR14_HUMAN
NC score	0.012222 (rank : 62)	θ value	2.36792 (rank : 57)
Query Neighborhood Hits	69	Target Neighborhood Hits	149	Shared Neighborhood Hits	9
SwissProt Accessions	Q92956, Q8WXR1, Q96J31, Q9UM65	Gene names	TNFRSF14, HVEA, HVEM
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 14 precursor (Herpesvirus entry mediator A) (Tumor necrosis factor receptor-like 2) (TR2).

ZAN_MOUSE
NC score	0.011863 (rank : 63)	θ value	0.0961366 (rank : 40)
Query Neighborhood Hits	69	Target Neighborhood Hits	808	Shared Neighborhood Hits	8
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

SMOO_HUMAN
NC score	0.009599 (rank : 64)	θ value	1.06291 (rank : 48)
Query Neighborhood Hits	69	Target Neighborhood Hits	391	Shared Neighborhood Hits	3
SwissProt Accessions	P53814, O00569, O95769, O95937, Q9P1S8, Q9UIT1, Q9UIT2	Gene names	SMTN, SMSMO
Domain Architecture
Description	Smoothelin.

TNR1B_MOUSE
NC score	0.007744 (rank : 65)	θ value	6.88961 (rank : 66)
Query Neighborhood Hits	69	Target Neighborhood Hits	123	Shared Neighborhood Hits	9
SwissProt Accessions	P25119, O88734, P97893	Gene names	Tnfrsf1b, Tnfr-2, Tnfr2
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 1B precursor (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (p75) (p80 TNF-alpha receptor).

SL9A9_MOUSE
NC score	0.007516 (rank : 66)	θ value	2.36792 (rank : 56)
Query Neighborhood Hits	69	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BZ00, Q3U0X0	Gene names	Slc9a9, Nhe9
Domain Architecture
Description	Sodium/hydrogen exchanger 9 (Na(+)/H(+) exchanger 9) (NHE-9) (Solute carrier family 9 member 9).

PCSK5_MOUSE
NC score	0.007073 (rank : 67)	θ value	1.81305 (rank : 52)
Query Neighborhood Hits	69	Target Neighborhood Hits	613	Shared Neighborhood Hits	10
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

NPAL1_HUMAN
NC score	0.005906 (rank : 68)	θ value	6.88961 (rank : 65)
Query Neighborhood Hits	69	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	Q6NVV3, Q68DA9	Gene names	NPAL1
Domain Architecture	No domain graphic available
Description	NIPA-like protein 1.

EPHA1_HUMAN
NC score	0.003372 (rank : 69)	θ value	2.36792 (rank : 53)
Query Neighborhood Hits	69	Target Neighborhood Hits	997	Shared Neighborhood Hits	14
SwissProt Accessions	P21709, Q15405	Gene names	EPHA1, EPH, EPHT, EPHT1
Domain Architecture
Description	Ephrin type-A receptor 1 precursor (EC 2.7.10.1) (Tyrosine-protein kinase receptor EPH).

PCOC2_HUMAN
NC score	0.003227 (rank : 70)	θ value	8.99809 (rank : 68)
Query Neighborhood Hits	69	Target Neighborhood Hits	73	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UKZ9, Q9BRH3	Gene names	PCOLCE2, PCPE2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

S12A2_MOUSE
NC score	0.002577 (rank : 71)	θ value	8.99809 (rank : 69)
Query Neighborhood Hits	69	Target Neighborhood Hits	55	Shared Neighborhood Hits	2
SwissProt Accessions	P55012	Gene names	Slc12a2, Nkcc1
Domain Architecture
Description	Solute carrier family 12 member 2 (Bumetanide-sensitive sodium- (potassium)-chloride cotransporter 1) (Basolateral Na-K-Cl symporter).

TRI65_MOUSE
NC score	0.002449 (rank : 72)	θ value	4.03905 (rank : 61)
Query Neighborhood Hits	69	Target Neighborhood Hits	340	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BFW4, Q6PGD3	Gene names	Trim65
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 65.

ABCAD_HUMAN
NC score	0.001721 (rank : 73)	θ value	6.88961 (rank : 63)
Query Neighborhood Hits	69	Target Neighborhood Hits	207	Shared Neighborhood Hits	2
SwissProt Accessions	Q86UQ4, Q6ZTT7, Q86WI2, Q8N248	Gene names	ABCA13
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 13.

ELTD1_HUMAN
NC score	0.001619 (rank : 74)	θ value	6.88961 (rank : 64)
Query Neighborhood Hits	69	Target Neighborhood Hits	269	Shared Neighborhood Hits	5
SwissProt Accessions	Q9HBW9	Gene names	ELTD1, ETL
Domain Architecture
Description	EGF, latrophilin and seven transmembrane domain-containing protein 1 precursor (EGF-TM7-latrophilin-related protein) (ETL protein).