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Network neighborhood for query Sequence : GP158_MOUSE

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GP158_MOUSE
SwissProt Accessions	Q8C419, Q8CHB0	Gene names	Gpr158, Kiaa1136
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 158 precursor.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

GP158_HUMAN
θ value	0 (rank : 1)	NC score	0.947091 (rank : 2)
Query Neighborhood Hits	82	Target Neighborhood Hits	221	Shared Neighborhood Hits	51
SwissProt Accessions	Q5T848, Q6QR81, Q9ULT3	Gene names	GPR158, KIAA1136
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 158 precursor.

GP158_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	82	Target Neighborhood Hits	82	Shared Neighborhood Hits	82
SwissProt Accessions	Q8C419, Q8CHB0	Gene names	Gpr158, Kiaa1136
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 158 precursor.

GP179_HUMAN
θ value	0 (rank : 3)	NC score	0.835928 (rank : 3)
Query Neighborhood Hits	82	Target Neighborhood Hits	372	Shared Neighborhood Hits	27
SwissProt Accessions	Q6PRD1	Gene names	GPR179, GPR158L1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 179 precursor (Probable G-protein coupled receptor 158-like 1).

MGR3_HUMAN
θ value	2.88788e-06 (rank : 4)	NC score	0.239088 (rank : 6)
Query Neighborhood Hits	82	Target Neighborhood Hits	58	Shared Neighborhood Hits	17
SwissProt Accessions	Q14832, Q75MV4, Q75N17, Q86YG6, Q8TBH9	Gene names	GRM3, GPRC1C, MGLUR3
Domain Architecture
Description	Metabotropic glutamate receptor 3 precursor (mGluR3).

MGR3_MOUSE
θ value	4.92598e-06 (rank : 5)	NC score	0.240750 (rank : 4)
Query Neighborhood Hits	82	Target Neighborhood Hits	54	Shared Neighborhood Hits	17
SwissProt Accessions	Q9QYS2	Gene names	Grm3, Gprc1c, Mglur3
Domain Architecture
Description	Metabotropic glutamate receptor 3 precursor (mGluR3).

MGR5_HUMAN
θ value	3.19293e-05 (rank : 6)	NC score	0.234193 (rank : 7)
Query Neighborhood Hits	82	Target Neighborhood Hits	72	Shared Neighborhood Hits	20
SwissProt Accessions	P41594	Gene names	GRM5, GPRC1E, MGLUR5
Domain Architecture
Description	Metabotropic glutamate receptor 5 precursor (mGluR5).

GABR2_HUMAN
θ value	0.000158464 (rank : 7)	NC score	0.239797 (rank : 5)
Query Neighborhood Hits	82	Target Neighborhood Hits	101	Shared Neighborhood Hits	20
SwissProt Accessions	O75899, O75974, O75975, Q5VXZ2, Q8WX04, Q9P1R2, Q9UNR1, Q9UNS9	Gene names	GABBR2, GPR51, GPRC3B
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 2 precursor (GABA-B receptor 2) (GABA-B-R2) (Gb2) (GABABR2) (G-protein coupled receptor 51) (HG20).

TITIN_HUMAN
θ value	0.000461057 (rank : 8)	NC score	0.022268 (rank : 76)
Query Neighborhood Hits	82	Target Neighborhood Hits	2923	Shared Neighborhood Hits	24
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

CASR_MOUSE
θ value	0.000602161 (rank : 9)	NC score	0.189388 (rank : 13)
Query Neighborhood Hits	82	Target Neighborhood Hits	72	Shared Neighborhood Hits	16
SwissProt Accessions	Q9QY96, O08968, O88519, Q9QY95, Q9QZU8, Q9R1D6, Q9R1Y2	Gene names	Casr, Gprc2a
Domain Architecture
Description	Extracellular calcium-sensing receptor precursor (CaSR) (Parathyroid Cell calcium-sensing receptor).

CASR_HUMAN
θ value	0.000786445 (rank : 10)	NC score	0.185332 (rank : 14)
Query Neighborhood Hits	82	Target Neighborhood Hits	71	Shared Neighborhood Hits	16
SwissProt Accessions	P41180, Q13912, Q16108, Q16109, Q16110, Q16379, Q4PJ19	Gene names	CASR, GPRC2A, PCAR1
Domain Architecture
Description	Extracellular calcium-sensing receptor precursor (CaSR) (Parathyroid Cell calcium-sensing receptor).

MGR1_MOUSE
θ value	0.000786445 (rank : 11)	NC score	0.225011 (rank : 9)
Query Neighborhood Hits	82	Target Neighborhood Hits	90	Shared Neighborhood Hits	18
SwissProt Accessions	P97772, Q6AXG4, Q9EPV6	Gene names	Grm1, Gprc1a, Mglur1
Domain Architecture
Description	Metabotropic glutamate receptor 1 precursor (mGluR1).

MGR1_HUMAN
θ value	0.00102713 (rank : 12)	NC score	0.226057 (rank : 8)
Query Neighborhood Hits	82	Target Neighborhood Hits	85	Shared Neighborhood Hits	18
SwissProt Accessions	Q13255, Q13256, Q14757, Q14758, Q5VTF7, Q5VTF8, Q9NU10, Q9UGS9, Q9UGT0	Gene names	GRM1, GPRC1A, MGLUR1
Domain Architecture
Description	Metabotropic glutamate receptor 1 precursor (mGluR1).

MGR2_HUMAN
θ value	0.00175202 (rank : 13)	NC score	0.216330 (rank : 10)
Query Neighborhood Hits	82	Target Neighborhood Hits	56	Shared Neighborhood Hits	19
SwissProt Accessions	Q14416, Q52MC6, Q9H3N6	Gene names	GRM2, GPRC1B, MGLUR2
Domain Architecture
Description	Metabotropic glutamate receptor 2 precursor (mGluR2).

MGR8_MOUSE
θ value	0.00228821 (rank : 14)	NC score	0.193821 (rank : 11)
Query Neighborhood Hits	82	Target Neighborhood Hits	44	Shared Neighborhood Hits	16
SwissProt Accessions	P47743, Q6B964	Gene names	Grm8, Gprc1h, Mglur8
Domain Architecture
Description	Metabotropic glutamate receptor 8 precursor (mGluR8).

MGR8_HUMAN
θ value	0.00390308 (rank : 15)	NC score	0.193165 (rank : 12)
Query Neighborhood Hits	82	Target Neighborhood Hits	49	Shared Neighborhood Hits	16
SwissProt Accessions	O00222, O15493, O95945, O95946, Q3MIV9, Q52M02, Q6J165	Gene names	GRM8, GPRC1H, MGLUR8
Domain Architecture
Description	Metabotropic glutamate receptor 8 precursor (mGluR8).

CBP_MOUSE
θ value	0.0252991 (rank : 16)	NC score	0.076919 (rank : 35)
Query Neighborhood Hits	82	Target Neighborhood Hits	1051	Shared Neighborhood Hits	13
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

GP156_MOUSE
θ value	0.0252991 (rank : 17)	NC score	0.141111 (rank : 20)
Query Neighborhood Hits	82	Target Neighborhood Hits	95	Shared Neighborhood Hits	13
SwissProt Accessions	Q6PCP7, Q8K452	Gene names	Gpr156, Gababl
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 156 (GABAB-related G-protein coupled receptor).

IF2P_HUMAN
θ value	0.0563607 (rank : 18)	NC score	0.051545 (rank : 38)
Query Neighborhood Hits	82	Target Neighborhood Hits	889	Shared Neighborhood Hits	17
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

LUZP1_MOUSE
θ value	0.0563607 (rank : 19)	NC score	0.040498 (rank : 48)
Query Neighborhood Hits	82	Target Neighborhood Hits	940	Shared Neighborhood Hits	13
SwissProt Accessions	Q8R4U7, Q3UV18, Q7TS71, Q8BQW1, Q99NG3, Q9CSL6	Gene names	Luzp1, Luzp
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1 (Leucine zipper motif-containing protein).

CBP_HUMAN
θ value	0.0736092 (rank : 20)	NC score	0.080621 (rank : 34)
Query Neighborhood Hits	82	Target Neighborhood Hits	941	Shared Neighborhood Hits	13
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

GP156_HUMAN
θ value	0.163984 (rank : 21)	NC score	0.124133 (rank : 31)
Query Neighborhood Hits	82	Target Neighborhood Hits	84	Shared Neighborhood Hits	11
SwissProt Accessions	Q8NFN8, Q86SN6	Gene names	GPR156, GABABL, PGR28
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 156 (GABAB-related G-protein coupled receptor) (G-protein coupled receptor PGR28).

MGR4_HUMAN
θ value	0.163984 (rank : 22)	NC score	0.182974 (rank : 16)
Query Neighborhood Hits	82	Target Neighborhood Hits	63	Shared Neighborhood Hits	18
SwissProt Accessions	Q14833, Q5SZ84	Gene names	GRM4, GPRC1D, MGLUR4
Domain Architecture
Description	Metabotropic glutamate receptor 4 precursor (mGluR4).

CENPC_MOUSE
θ value	0.21417 (rank : 23)	NC score	0.049936 (rank : 39)
Query Neighborhood Hits	82	Target Neighborhood Hits	154	Shared Neighborhood Hits	5
SwissProt Accessions	P49452	Gene names	Cenpc1, Cenpc
Domain Architecture	No domain graphic available
Description	Centromere protein C 1 (CENP-C) (Centromere autoantigen C).

NIPBL_HUMAN
θ value	0.21417 (rank : 24)	NC score	0.044818 (rank : 44)
Query Neighborhood Hits	82	Target Neighborhood Hits	1311	Shared Neighborhood Hits	21
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

CENPE_HUMAN
θ value	0.279714 (rank : 25)	NC score	0.012250 (rank : 87)
Query Neighborhood Hits	82	Target Neighborhood Hits	2060	Shared Neighborhood Hits	14
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

FBN1_HUMAN
θ value	0.279714 (rank : 26)	NC score	0.048451 (rank : 42)
Query Neighborhood Hits	82	Target Neighborhood Hits	557	Shared Neighborhood Hits	20
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

RGL2_MOUSE
θ value	0.279714 (rank : 27)	NC score	0.029466 (rank : 61)
Query Neighborhood Hits	82	Target Neighborhood Hits	51	Shared Neighborhood Hits	2
SwissProt Accessions	Q61193, Q9QUJ2	Gene names	Rgl2, Rab2l, Rlf
Domain Architecture
Description	Ral guanine nucleotide dissociation stimulator-like 2 (RalGDS-like factor) (RAS-associated protein RAB2L).

ZN236_HUMAN
θ value	0.279714 (rank : 28)	NC score	0.003914 (rank : 97)
Query Neighborhood Hits	82	Target Neighborhood Hits	844	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UL36, Q9UL37	Gene names	ZNF236
Domain Architecture	No domain graphic available
Description	Zinc finger protein 236.

FBN1_MOUSE
θ value	0.365318 (rank : 29)	NC score	0.048626 (rank : 40)
Query Neighborhood Hits	82	Target Neighborhood Hits	563	Shared Neighborhood Hits	22
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

FBN2_HUMAN
θ value	0.47712 (rank : 30)	NC score	0.048496 (rank : 41)
Query Neighborhood Hits	82	Target Neighborhood Hits	560	Shared Neighborhood Hits	20
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

MINT_MOUSE
θ value	0.62314 (rank : 31)	NC score	0.039833 (rank : 49)
Query Neighborhood Hits	82	Target Neighborhood Hits	1514	Shared Neighborhood Hits	26
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

NOTC1_MOUSE
θ value	0.62314 (rank : 32)	NC score	0.036194 (rank : 52)
Query Neighborhood Hits	82	Target Neighborhood Hits	916	Shared Neighborhood Hits	20
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

TRPC5_MOUSE
θ value	0.62314 (rank : 33)	NC score	0.017862 (rank : 80)
Query Neighborhood Hits	82	Target Neighborhood Hits	124	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QX29, Q61059, Q9QWT1, Q9R0D4	Gene names	Trpc5, Trp5, Trrp5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Transient receptor protein 5) (Mtrp5) (trp-related protein 5) (Capacitative calcium entry channel 2) (CCE2).

FBLN2_HUMAN
θ value	0.813845 (rank : 34)	NC score	0.039581 (rank : 50)
Query Neighborhood Hits	82	Target Neighborhood Hits	392	Shared Neighborhood Hits	19
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

ITPR3_HUMAN
θ value	0.813845 (rank : 35)	NC score	0.032764 (rank : 56)
Query Neighborhood Hits	82	Target Neighborhood Hits	114	Shared Neighborhood Hits	7
SwissProt Accessions	Q14573, Q14649	Gene names	ITPR3
Domain Architecture
Description	Inositol 1,4,5-trisphosphate receptor type 3 (Type 3 inositol 1,4,5- trisphosphate receptor) (Type 3 InsP3 receptor) (IP3 receptor isoform 3) (InsP3R3).

ITPR3_MOUSE
θ value	0.813845 (rank : 36)	NC score	0.032412 (rank : 57)
Query Neighborhood Hits	82	Target Neighborhood Hits	105	Shared Neighborhood Hits	4
SwissProt Accessions	P70227, Q5DWM4, Q8CED5, Q91Z08	Gene names	Itpr3
Domain Architecture	No domain graphic available
Description	Inositol 1,4,5-trisphosphate receptor type 3 (Type 3 inositol 1,4,5- trisphosphate receptor) (Type 3 InsP3 receptor) (IP3 receptor isoform 3) (InsP3R3).

MGR6_HUMAN
θ value	0.813845 (rank : 37)	NC score	0.183117 (rank : 15)
Query Neighborhood Hits	82	Target Neighborhood Hits	58	Shared Neighborhood Hits	19
SwissProt Accessions	O15303	Gene names	GRM6, GPRC1F, MGLUR6
Domain Architecture
Description	Metabotropic glutamate receptor 6 precursor (mGluR6).

NELL1_HUMAN
θ value	0.813845 (rank : 38)	NC score	0.037832 (rank : 51)
Query Neighborhood Hits	82	Target Neighborhood Hits	451	Shared Neighborhood Hits	19
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

FBN2_MOUSE
θ value	1.06291 (rank : 39)	NC score	0.047925 (rank : 43)
Query Neighborhood Hits	82	Target Neighborhood Hits	549	Shared Neighborhood Hits	20
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

MGR6_MOUSE
θ value	1.06291 (rank : 40)	NC score	0.175107 (rank : 17)
Query Neighborhood Hits	82	Target Neighborhood Hits	56	Shared Neighborhood Hits	19
SwissProt Accessions	Q5NCH9	Gene names	Grm6, Gprc1f, Mglur6
Domain Architecture	No domain graphic available
Description	Metabotropic glutamate receptor 6 precursor (mGluR6).

PHF20_MOUSE
θ value	1.06291 (rank : 41)	NC score	0.040874 (rank : 47)
Query Neighborhood Hits	82	Target Neighborhood Hits	513	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

SETX_HUMAN
θ value	1.06291 (rank : 42)	NC score	0.028385 (rank : 64)
Query Neighborhood Hits	82	Target Neighborhood Hits	368	Shared Neighborhood Hits	8
SwissProt Accessions	Q7Z333, O75120, Q3KQX4, Q68DW5, Q6AZD7, Q7Z3J6, Q8WX33, Q9H9D1, Q9NVP9	Gene names	SETX, ALS4, KIAA0625, SCAR1
Domain Architecture
Description	Probable helicase senataxin (EC 3.6.1.-) (SEN1 homolog).

EMR1_MOUSE
θ value	1.38821 (rank : 43)	NC score	0.028959 (rank : 62)
Query Neighborhood Hits	82	Target Neighborhood Hits	349	Shared Neighborhood Hits	18
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

PHF20_HUMAN
θ value	1.38821 (rank : 44)	NC score	0.041473 (rank : 45)
Query Neighborhood Hits	82	Target Neighborhood Hits	394	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BVI0, Q5JWY9, Q9BWV4, Q9BXA3, Q9BZW3, Q9H421, Q9H4J6, Q9NZ22	Gene names	PHF20, C20orf104, GLEA2, HCA58, NZF, TZP
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58) (Glioma-expressed antigen 2) (Transcription factor TZP) (Novel zinc finger protein).

RAI1_MOUSE
θ value	1.38821 (rank : 45)	NC score	0.024119 (rank : 74)
Query Neighborhood Hits	82	Target Neighborhood Hits	344	Shared Neighborhood Hits	5
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

Z297B_MOUSE
θ value	1.38821 (rank : 46)	NC score	0.006485 (rank : 94)
Query Neighborhood Hits	82	Target Neighborhood Hits	806	Shared Neighborhood Hits	5
SwissProt Accessions	Q9DAI4	Gene names	Znf297b, Kiaa0414, Zfp297b
Domain Architecture
Description	Zinc finger protein 297B.

ABR_HUMAN
θ value	1.81305 (rank : 47)	NC score	0.011912 (rank : 88)
Query Neighborhood Hits	82	Target Neighborhood Hits	166	Shared Neighborhood Hits	3
SwissProt Accessions	Q12979, Q13693, Q13694	Gene names	ABR
Domain Architecture
Description	Active breakpoint cluster region-related protein.

AP2A_HUMAN
θ value	1.81305 (rank : 48)	NC score	0.027907 (rank : 66)
Query Neighborhood Hits	82	Target Neighborhood Hits	36	Shared Neighborhood Hits	4
SwissProt Accessions	P05549, Q13777	Gene names	TFAP2A, AP2TF, TFAP2
Domain Architecture
Description	Transcription factor AP-2 alpha (AP2-alpha) (Activating enhancer- binding protein 2 alpha) (AP-2 transcription factor) (Activator protein 2) (AP-2).

AP2A_MOUSE
θ value	1.81305 (rank : 49)	NC score	0.027692 (rank : 68)
Query Neighborhood Hits	82	Target Neighborhood Hits	36	Shared Neighborhood Hits	4
SwissProt Accessions	P34056, Q60740, Q60741, Q60742, Q60743, Q62067, Q62068, Q62069, Q91VX0, Q9CRY4	Gene names	Tfap2a, Ap2tf, Tcfap2a
Domain Architecture
Description	Transcription factor AP-2 alpha (AP2-alpha) (Activating enhancer- binding protein 2 alpha) (Activator protein 2) (AP-2).

G109B_HUMAN
θ value	1.81305 (rank : 50)	NC score	0.006178 (rank : 95)
Query Neighborhood Hits	82	Target Neighborhood Hits	579	Shared Neighborhood Hits	3
SwissProt Accessions	P49019, Q8NGE4	Gene names	GPR109B
Domain Architecture
Description	Nicotinic acid receptor 2 (G-protein coupled receptor 109B) (G-protein coupled receptor HM74) (G-protein coupled receptor HM74B).

REPS1_MOUSE
θ value	1.81305 (rank : 51)	NC score	0.025550 (rank : 71)
Query Neighborhood Hits	82	Target Neighborhood Hits	204	Shared Neighborhood Hits	4
SwissProt Accessions	O54916, Q8C9J9, Q99LR8	Gene names	Reps1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1).

RIOK2_HUMAN
θ value	1.81305 (rank : 52)	NC score	0.028201 (rank : 65)
Query Neighborhood Hits	82	Target Neighborhood Hits	125	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BVS4, Q9NUT0	Gene names	RIOK2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase RIO2 (EC 2.7.11.1) (RIO kinase 2).

Z297B_HUMAN
θ value	1.81305 (rank : 53)	NC score	0.005968 (rank : 96)
Query Neighborhood Hits	82	Target Neighborhood Hits	792	Shared Neighborhood Hits	4
SwissProt Accessions	O43298	Gene names	ZNF297B, KIAA0414, ZBTB22B
Domain Architecture
Description	Zinc finger protein 297B (ZnF-x) (Zinc finger and BTB domain- containing protein 22B).

LIMA1_HUMAN
θ value	2.36792 (rank : 54)	NC score	0.027063 (rank : 69)
Query Neighborhood Hits	82	Target Neighborhood Hits	309	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UHB6, Q2TAN7, Q9BVF2, Q9H8J1, Q9HBN5, Q9NX96, Q9NXC3, Q9NXU6, Q9P0H8, Q9UHB5	Gene names	LIMA1, EPLIN, SREBP3
Domain Architecture
Description	LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm).

RENT2_HUMAN
θ value	2.36792 (rank : 55)	NC score	0.028879 (rank : 63)
Query Neighborhood Hits	82	Target Neighborhood Hits	618	Shared Neighborhood Hits	11
SwissProt Accessions	Q9HAU5, Q8N8U1, Q9H1J2, Q9NWL1, Q9P2D9, Q9Y4M9	Gene names	UPF2, KIAA1408, RENT2
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 2 (Nonsense mRNA reducing factor 2) (Up-frameshift suppressor 2 homolog) (hUpf2).

RXINP_HUMAN
θ value	2.36792 (rank : 56)	NC score	0.024971 (rank : 73)
Query Neighborhood Hits	82	Target Neighborhood Hits	87	Shared Neighborhood Hits	2
SwissProt Accessions	Q96RL1, Q5XKQ1, Q7Z3W7, Q8N5B9, Q9BZR1, Q9BZR5, Q9UHX7	Gene names	RXRIP110, RAP80
Domain Architecture	No domain graphic available
Description	Retinoid X receptor-interacting protein 110 (Receptor-associated protein 80) (Nuclear zinc finger protein RAP80).

TACC2_MOUSE
θ value	2.36792 (rank : 57)	NC score	0.016499 (rank : 83)
Query Neighborhood Hits	82	Target Neighborhood Hits	774	Shared Neighborhood Hits	13
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

ABCA9_MOUSE
θ value	3.0926 (rank : 58)	NC score	0.017610 (rank : 81)
Query Neighborhood Hits	82	Target Neighborhood Hits	107	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K449, Q8C114	Gene names	Abca9
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 9.

EDEM3_HUMAN
θ value	3.0926 (rank : 59)	NC score	0.015715 (rank : 86)
Query Neighborhood Hits	82	Target Neighborhood Hits	92	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BZQ6, Q5TEZ0, Q9HCW1, Q9UFV7	Gene names	EDEM3, C1orf22
Domain Architecture
Description	ER degradation-enhancing alpha-mannosidase-like 3.

NOTC2_MOUSE
θ value	3.0926 (rank : 60)	NC score	0.032898 (rank : 55)
Query Neighborhood Hits	82	Target Neighborhood Hits	1069	Shared Neighborhood Hits	24
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

TOPB1_HUMAN
θ value	3.0926 (rank : 61)	NC score	0.019406 (rank : 79)
Query Neighborhood Hits	82	Target Neighborhood Hits	82	Shared Neighborhood Hits	3
SwissProt Accessions	Q92547, Q7LGC1, Q9UEB9	Gene names	TOPBP1, KIAA0259
Domain Architecture	No domain graphic available
Description	DNA topoisomerase 2-binding protein 1 (DNA topoisomerase II-binding protein 1) (DNA topoisomerase IIbeta-binding protein 1) (TopBP1).

CE290_HUMAN
θ value	4.03905 (rank : 62)	NC score	0.010727 (rank : 90)
Query Neighborhood Hits	82	Target Neighborhood Hits	1553	Shared Neighborhood Hits	14
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

TSC2_HUMAN
θ value	4.03905 (rank : 63)	NC score	0.022958 (rank : 75)
Query Neighborhood Hits	82	Target Neighborhood Hits	59	Shared Neighborhood Hits	4
SwissProt Accessions	P49815, O75275, Q8TAZ1	Gene names	TSC2
Domain Architecture
Description	Tuberin (Tuberous sclerosis 2 protein).

ABCA9_HUMAN
θ value	5.27518 (rank : 64)	NC score	0.016732 (rank : 82)
Query Neighborhood Hits	82	Target Neighborhood Hits	111	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IUA7, Q6P655, Q8N2S4, Q8WWZ5, Q96MD8	Gene names	ABCA9
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 9.

AIM1_HUMAN
θ value	5.27518 (rank : 65)	NC score	0.024998 (rank : 72)
Query Neighborhood Hits	82	Target Neighborhood Hits	247	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y4K1, O00296, Q5VWJ2	Gene names	AIM1
Domain Architecture
Description	Absent in melanoma 1 protein.

ATRX_MOUSE
θ value	5.27518 (rank : 66)	NC score	0.035025 (rank : 54)
Query Neighborhood Hits	82	Target Neighborhood Hits	682	Shared Neighborhood Hits	14
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

O51I1_HUMAN
θ value	5.27518 (rank : 67)	NC score	-0.000108 (rank : 98)
Query Neighborhood Hits	82	Target Neighborhood Hits	756	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H343, Q6IF33	Gene names	OR51I1
Domain Architecture
Description	Olfactory receptor 51I1 (Odorant receptor HOR5'beta11) (Olfactory receptor OR11-39).

TNR6A_HUMAN
θ value	5.27518 (rank : 68)	NC score	0.019531 (rank : 78)
Query Neighborhood Hits	82	Target Neighborhood Hits	343	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NDV7, O15408, Q658L5, Q6NVB5, Q8NEZ0, Q8TBT8, Q8TCR0, Q9NV59, Q9P268	Gene names	TNRC6A, CAGH26, KIAA1460, TNRC6
Domain Architecture	No domain graphic available
Description	Trinucleotide repeat-containing gene 6A protein (CAG repeat protein 26) (Glycine-tryptophan protein of 182 kDa) (GW182 autoantigen) (Protein GW1) (EMSY interactor protein).

ABCA8_HUMAN
θ value	6.88961 (rank : 69)	NC score	0.015720 (rank : 85)
Query Neighborhood Hits	82	Target Neighborhood Hits	113	Shared Neighborhood Hits	5
SwissProt Accessions	O94911, Q86WW0	Gene names	ABCA8, KIAA0822
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 8.

FRAS1_HUMAN
θ value	6.88961 (rank : 70)	NC score	0.016315 (rank : 84)
Query Neighborhood Hits	82	Target Neighborhood Hits	759	Shared Neighborhood Hits	19
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

HMCN1_HUMAN
θ value	6.88961 (rank : 71)	NC score	0.027838 (rank : 67)
Query Neighborhood Hits	82	Target Neighborhood Hits	983	Shared Neighborhood Hits	21
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

MTMR5_HUMAN
θ value	6.88961 (rank : 72)	NC score	0.008799 (rank : 92)
Query Neighborhood Hits	82	Target Neighborhood Hits	141	Shared Neighborhood Hits	3
SwissProt Accessions	O95248, O60228, Q5JXD8, Q5PPM2, Q96GR9, Q9UGB8	Gene names	SBF1, MTMR5
Domain Architecture
Description	SET-binding factor 1 (Sbf1) (Myotubularin-related protein 5).

NCOR2_HUMAN
θ value	6.88961 (rank : 73)	NC score	0.021111 (rank : 77)
Query Neighborhood Hits	82	Target Neighborhood Hits	870	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

TBC10_MOUSE
θ value	6.88961 (rank : 74)	NC score	0.009413 (rank : 91)
Query Neighborhood Hits	82	Target Neighborhood Hits	94	Shared Neighborhood Hits	2
SwissProt Accessions	P58802	Gene names	Tbc1d10a, Epi64, Tbc1d10
Domain Architecture
Description	TBC1 domain family member 10A (EBP50-PDX interactor of 64 kDa) (EPI64 protein).

EMR1_HUMAN
θ value	8.99809 (rank : 75)	NC score	0.026106 (rank : 70)
Query Neighborhood Hits	82	Target Neighborhood Hits	382	Shared Neighborhood Hits	18
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

FBLN1_MOUSE
θ value	8.99809 (rank : 76)	NC score	0.035583 (rank : 53)
Query Neighborhood Hits	82	Target Neighborhood Hits	329	Shared Neighborhood Hits	19
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

FBN3_HUMAN
θ value	8.99809 (rank : 77)	NC score	0.041070 (rank : 46)
Query Neighborhood Hits	82	Target Neighborhood Hits	543	Shared Neighborhood Hits	20
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

LTB1L_HUMAN
θ value	8.99809 (rank : 78)	NC score	0.031907 (rank : 58)
Query Neighborhood Hits	82	Target Neighborhood Hits	553	Shared Neighborhood Hits	22
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
θ value	8.99809 (rank : 79)	NC score	0.031368 (rank : 59)
Query Neighborhood Hits	82	Target Neighborhood Hits	502	Shared Neighborhood Hits	20
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTBP3_HUMAN
θ value	8.99809 (rank : 80)	NC score	0.031049 (rank : 60)
Query Neighborhood Hits	82	Target Neighborhood Hits	502	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

NBEA_HUMAN
θ value	8.99809 (rank : 81)	NC score	0.008713 (rank : 93)
Query Neighborhood Hits	82	Target Neighborhood Hits	186	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NFP9, Q9HCM8, Q9NSU1, Q9NW98, Q9Y6J1	Gene names	NBEA, BCL8B, KIAA1544, LYST2
Domain Architecture
Description	Protein neurobeachin (Lysosomal-trafficking regulator 2) (Protein BCL8B).

ST5_MOUSE
θ value	8.99809 (rank : 82)	NC score	0.010806 (rank : 89)
Query Neighborhood Hits	82	Target Neighborhood Hits	126	Shared Neighborhood Hits	5
SwissProt Accessions	Q924W7, Q78H54, Q8K2P3, Q924W8	Gene names	St5, Dennd2b
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity 5 (DENN domain-containing protein 2B).

GABR1_HUMAN
θ value	θ > 10 (rank : 83)	NC score	0.094516 (rank : 33)
Query Neighborhood Hits	82	Target Neighborhood Hits	142	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UBS5, O95375, O95468, O95975, O96022, Q86W60, Q9UQQ0	Gene names	GABBR1, GPRC3A
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

GABR1_MOUSE
θ value	θ > 10 (rank : 84)	NC score	0.095106 (rank : 32)
Query Neighborhood Hits	82	Target Neighborhood Hits	139	Shared Neighborhood Hits	17
SwissProt Accessions	Q9WV18, Q9WU48, Q9WV15, Q9WV16, Q9WV17	Gene names	Gabbr1
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

GPC5B_HUMAN
θ value	θ > 10 (rank : 85)	NC score	0.057609 (rank : 37)
Query Neighborhood Hits	82	Target Neighborhood Hits	28	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NZH0, O75205, Q8NBZ8	Gene names	GPRC5B, RAIG2
Domain Architecture
Description	G-protein coupled receptor family C group 5 member B precursor (Retinoic acid-induced gene 2 protein) (RAIG-2) (A-69G12.1).

GPC5B_MOUSE
θ value	θ > 10 (rank : 86)	NC score	0.060466 (rank : 36)
Query Neighborhood Hits	82	Target Neighborhood Hits	33	Shared Neighborhood Hits	13
SwissProt Accessions	Q923Z0, Q8CCV3	Gene names	Gprc5b, Raig2
Domain Architecture
Description	G-protein coupled receptor family C group 5 member B precursor (Retinoic acid-induced gene 2 protein) (RAIG-2).

GPC6A_HUMAN
θ value	θ > 10 (rank : 87)	NC score	0.133560 (rank : 23)
Query Neighborhood Hits	82	Target Neighborhood Hits	53	Shared Neighborhood Hits	14
SwissProt Accessions	Q5T6X5, Q6JK43, Q6JK44, Q8NGU8, Q8NHZ9, Q8TDT6	Gene names	GPRC6A, GPCR33
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor family C group 6 member A precursor (hGPRC6A) (G-protein coupled receptor 33) (hGPCR33).

GPC6A_MOUSE
θ value	θ > 10 (rank : 88)	NC score	0.132514 (rank : 24)
Query Neighborhood Hits	82	Target Neighborhood Hits	57	Shared Neighborhood Hits	14
SwissProt Accessions	Q8K4Z6, Q5DK51, Q5DK52	Gene names	Gprc6a
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor family C group 6 member A precursor.

MGR7_HUMAN
θ value	θ > 10 (rank : 89)	NC score	0.171361 (rank : 18)
Query Neighborhood Hits	82	Target Neighborhood Hits	52	Shared Neighborhood Hits	17
SwissProt Accessions	Q14831, Q8NFS2, Q8NFS3, Q8NFS4	Gene names	GRM7, GPRC1G, MGLUR7
Domain Architecture
Description	Metabotropic glutamate receptor 7 precursor (mGluR7).

MGR7_MOUSE
θ value	θ > 10 (rank : 90)	NC score	0.169931 (rank : 19)
Query Neighborhood Hits	82	Target Neighborhood Hits	53	Shared Neighborhood Hits	17
SwissProt Accessions	Q68ED2	Gene names	Grm7, Gprc1g, Mglur7
Domain Architecture	No domain graphic available
Description	Metabotropic glutamate receptor 7 precursor (mGluR7).

TS1R1_HUMAN
θ value	θ > 10 (rank : 91)	NC score	0.132284 (rank : 25)
Query Neighborhood Hits	82	Target Neighborhood Hits	72	Shared Neighborhood Hits	15
SwissProt Accessions	Q7RTX1, Q8NGZ7, Q8TDJ7, Q8TDJ8, Q8TDJ9, Q8TDK0	Gene names	TAS1R1, GPR70, T1R1, TR1
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 1 precursor (G-protein coupled receptor 70) (Gm148).

TS1R1_MOUSE
θ value	θ > 10 (rank : 92)	NC score	0.127385 (rank : 28)
Query Neighborhood Hits	82	Target Neighborhood Hits	57	Shared Neighborhood Hits	15
SwissProt Accessions	Q99PG6, Q6NS58, Q923J9, Q925I5, Q99PG5	Gene names	Tas1r1, Gpr70, T1r1, Tr1
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 1 precursor (G-protein coupled receptor 70).

TS1R2_HUMAN
θ value	θ > 10 (rank : 93)	NC score	0.127505 (rank : 27)
Query Neighborhood Hits	82	Target Neighborhood Hits	48	Shared Neighborhood Hits	14
SwissProt Accessions	Q8TE23, Q5TZ19	Gene names	TAS1R2, GPR71, T1R2, TR2
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 2 precursor (G-protein coupled receptor 71) (Sweet taste receptor T1R2).

TS1R2_MOUSE
θ value	θ > 10 (rank : 94)	NC score	0.129778 (rank : 26)
Query Neighborhood Hits	82	Target Neighborhood Hits	69	Shared Neighborhood Hits	15
SwissProt Accessions	Q925I4, Q923J8	Gene names	Tas1r2, Gpr71, T1r2, Tr2
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 2 precursor (G-protein coupled receptor 71) (Sweet taste receptor T1R2).

TS1R3_HUMAN
θ value	θ > 10 (rank : 95)	NC score	0.124727 (rank : 30)
Query Neighborhood Hits	82	Target Neighborhood Hits	46	Shared Neighborhood Hits	14
SwissProt Accessions	Q7RTX0, Q5TA49, Q8NGW9	Gene names	TAS1R3, T1R3, TR3
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 3 precursor (Sweet taste receptor T1R3).

TS1R3_MOUSE
θ value	θ > 10 (rank : 96)	NC score	0.126021 (rank : 29)
Query Neighborhood Hits	82	Target Neighborhood Hits	49	Shared Neighborhood Hits	14
SwissProt Accessions	Q925D8, Q91VA4, Q923K0, Q925A4, Q925D9	Gene names	Tas1r3, Sac, T1r3, Tr3
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 3 precursor (Sweet taste receptor T1R3) (Saccharin preference protein).

V2R1B_MOUSE
θ value	θ > 10 (rank : 97)	NC score	0.139586 (rank : 22)
Query Neighborhood Hits	82	Target Neighborhood Hits	39	Shared Neighborhood Hits	14
SwissProt Accessions	Q6TAC4, O70409	Gene names	V2r1b
Domain Architecture	No domain graphic available
Description	Vomeronasal type-2 receptor 1b precursor (Putative pheromone receptor V2R1b).

V2RX_MOUSE
θ value	θ > 10 (rank : 98)	NC score	0.140992 (rank : 21)
Query Neighborhood Hits	82	Target Neighborhood Hits	45	Shared Neighborhood Hits	14
SwissProt Accessions	O70410	Gene names
Domain Architecture	No domain graphic available
Description	Vomeronasal type-2 receptor X precursor (Putative pheromone receptor V2RX).

Hits sorted by NC score

GP158_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	82	Target Neighborhood Hits	82	Shared Neighborhood Hits	82
SwissProt Accessions	Q8C419, Q8CHB0	Gene names	Gpr158, Kiaa1136
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 158 precursor.

GP158_HUMAN
NC score	0.947091 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	82	Target Neighborhood Hits	221	Shared Neighborhood Hits	51
SwissProt Accessions	Q5T848, Q6QR81, Q9ULT3	Gene names	GPR158, KIAA1136
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 158 precursor.

GP179_HUMAN
NC score	0.835928 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	82	Target Neighborhood Hits	372	Shared Neighborhood Hits	27
SwissProt Accessions	Q6PRD1	Gene names	GPR179, GPR158L1
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 179 precursor (Probable G-protein coupled receptor 158-like 1).

MGR3_MOUSE
NC score	0.240750 (rank : 4)	θ value	4.92598e-06 (rank : 5)
Query Neighborhood Hits	82	Target Neighborhood Hits	54	Shared Neighborhood Hits	17
SwissProt Accessions	Q9QYS2	Gene names	Grm3, Gprc1c, Mglur3
Domain Architecture
Description	Metabotropic glutamate receptor 3 precursor (mGluR3).

GABR2_HUMAN
NC score	0.239797 (rank : 5)	θ value	0.000158464 (rank : 7)
Query Neighborhood Hits	82	Target Neighborhood Hits	101	Shared Neighborhood Hits	20
SwissProt Accessions	O75899, O75974, O75975, Q5VXZ2, Q8WX04, Q9P1R2, Q9UNR1, Q9UNS9	Gene names	GABBR2, GPR51, GPRC3B
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 2 precursor (GABA-B receptor 2) (GABA-B-R2) (Gb2) (GABABR2) (G-protein coupled receptor 51) (HG20).

MGR3_HUMAN
NC score	0.239088 (rank : 6)	θ value	2.88788e-06 (rank : 4)
Query Neighborhood Hits	82	Target Neighborhood Hits	58	Shared Neighborhood Hits	17
SwissProt Accessions	Q14832, Q75MV4, Q75N17, Q86YG6, Q8TBH9	Gene names	GRM3, GPRC1C, MGLUR3
Domain Architecture
Description	Metabotropic glutamate receptor 3 precursor (mGluR3).

MGR5_HUMAN
NC score	0.234193 (rank : 7)	θ value	3.19293e-05 (rank : 6)
Query Neighborhood Hits	82	Target Neighborhood Hits	72	Shared Neighborhood Hits	20
SwissProt Accessions	P41594	Gene names	GRM5, GPRC1E, MGLUR5
Domain Architecture
Description	Metabotropic glutamate receptor 5 precursor (mGluR5).

MGR1_HUMAN
NC score	0.226057 (rank : 8)	θ value	0.00102713 (rank : 12)
Query Neighborhood Hits	82	Target Neighborhood Hits	85	Shared Neighborhood Hits	18
SwissProt Accessions	Q13255, Q13256, Q14757, Q14758, Q5VTF7, Q5VTF8, Q9NU10, Q9UGS9, Q9UGT0	Gene names	GRM1, GPRC1A, MGLUR1
Domain Architecture
Description	Metabotropic glutamate receptor 1 precursor (mGluR1).

MGR1_MOUSE
NC score	0.225011 (rank : 9)	θ value	0.000786445 (rank : 11)
Query Neighborhood Hits	82	Target Neighborhood Hits	90	Shared Neighborhood Hits	18
SwissProt Accessions	P97772, Q6AXG4, Q9EPV6	Gene names	Grm1, Gprc1a, Mglur1
Domain Architecture
Description	Metabotropic glutamate receptor 1 precursor (mGluR1).

MGR2_HUMAN
NC score	0.216330 (rank : 10)	θ value	0.00175202 (rank : 13)
Query Neighborhood Hits	82	Target Neighborhood Hits	56	Shared Neighborhood Hits	19
SwissProt Accessions	Q14416, Q52MC6, Q9H3N6	Gene names	GRM2, GPRC1B, MGLUR2
Domain Architecture
Description	Metabotropic glutamate receptor 2 precursor (mGluR2).

MGR8_MOUSE
NC score	0.193821 (rank : 11)	θ value	0.00228821 (rank : 14)
Query Neighborhood Hits	82	Target Neighborhood Hits	44	Shared Neighborhood Hits	16
SwissProt Accessions	P47743, Q6B964	Gene names	Grm8, Gprc1h, Mglur8
Domain Architecture
Description	Metabotropic glutamate receptor 8 precursor (mGluR8).

MGR8_HUMAN
NC score	0.193165 (rank : 12)	θ value	0.00390308 (rank : 15)
Query Neighborhood Hits	82	Target Neighborhood Hits	49	Shared Neighborhood Hits	16
SwissProt Accessions	O00222, O15493, O95945, O95946, Q3MIV9, Q52M02, Q6J165	Gene names	GRM8, GPRC1H, MGLUR8
Domain Architecture
Description	Metabotropic glutamate receptor 8 precursor (mGluR8).

CASR_MOUSE
NC score	0.189388 (rank : 13)	θ value	0.000602161 (rank : 9)
Query Neighborhood Hits	82	Target Neighborhood Hits	72	Shared Neighborhood Hits	16
SwissProt Accessions	Q9QY96, O08968, O88519, Q9QY95, Q9QZU8, Q9R1D6, Q9R1Y2	Gene names	Casr, Gprc2a
Domain Architecture
Description	Extracellular calcium-sensing receptor precursor (CaSR) (Parathyroid Cell calcium-sensing receptor).

CASR_HUMAN
NC score	0.185332 (rank : 14)	θ value	0.000786445 (rank : 10)
Query Neighborhood Hits	82	Target Neighborhood Hits	71	Shared Neighborhood Hits	16
SwissProt Accessions	P41180, Q13912, Q16108, Q16109, Q16110, Q16379, Q4PJ19	Gene names	CASR, GPRC2A, PCAR1
Domain Architecture
Description	Extracellular calcium-sensing receptor precursor (CaSR) (Parathyroid Cell calcium-sensing receptor).

MGR6_HUMAN
NC score	0.183117 (rank : 15)	θ value	0.813845 (rank : 37)
Query Neighborhood Hits	82	Target Neighborhood Hits	58	Shared Neighborhood Hits	19
SwissProt Accessions	O15303	Gene names	GRM6, GPRC1F, MGLUR6
Domain Architecture
Description	Metabotropic glutamate receptor 6 precursor (mGluR6).

MGR4_HUMAN
NC score	0.182974 (rank : 16)	θ value	0.163984 (rank : 22)
Query Neighborhood Hits	82	Target Neighborhood Hits	63	Shared Neighborhood Hits	18
SwissProt Accessions	Q14833, Q5SZ84	Gene names	GRM4, GPRC1D, MGLUR4
Domain Architecture
Description	Metabotropic glutamate receptor 4 precursor (mGluR4).

MGR6_MOUSE
NC score	0.175107 (rank : 17)	θ value	1.06291 (rank : 40)
Query Neighborhood Hits	82	Target Neighborhood Hits	56	Shared Neighborhood Hits	19
SwissProt Accessions	Q5NCH9	Gene names	Grm6, Gprc1f, Mglur6
Domain Architecture	No domain graphic available
Description	Metabotropic glutamate receptor 6 precursor (mGluR6).

MGR7_HUMAN
NC score	0.171361 (rank : 18)	θ value	θ > 10 (rank : 89)
Query Neighborhood Hits	82	Target Neighborhood Hits	52	Shared Neighborhood Hits	17
SwissProt Accessions	Q14831, Q8NFS2, Q8NFS3, Q8NFS4	Gene names	GRM7, GPRC1G, MGLUR7
Domain Architecture
Description	Metabotropic glutamate receptor 7 precursor (mGluR7).

MGR7_MOUSE
NC score	0.169931 (rank : 19)	θ value	θ > 10 (rank : 90)
Query Neighborhood Hits	82	Target Neighborhood Hits	53	Shared Neighborhood Hits	17
SwissProt Accessions	Q68ED2	Gene names	Grm7, Gprc1g, Mglur7
Domain Architecture	No domain graphic available
Description	Metabotropic glutamate receptor 7 precursor (mGluR7).

GP156_MOUSE
NC score	0.141111 (rank : 20)	θ value	0.0252991 (rank : 17)
Query Neighborhood Hits	82	Target Neighborhood Hits	95	Shared Neighborhood Hits	13
SwissProt Accessions	Q6PCP7, Q8K452	Gene names	Gpr156, Gababl
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 156 (GABAB-related G-protein coupled receptor).

V2RX_MOUSE
NC score	0.140992 (rank : 21)	θ value	θ > 10 (rank : 98)
Query Neighborhood Hits	82	Target Neighborhood Hits	45	Shared Neighborhood Hits	14
SwissProt Accessions	O70410	Gene names
Domain Architecture	No domain graphic available
Description	Vomeronasal type-2 receptor X precursor (Putative pheromone receptor V2RX).

V2R1B_MOUSE
NC score	0.139586 (rank : 22)	θ value	θ > 10 (rank : 97)
Query Neighborhood Hits	82	Target Neighborhood Hits	39	Shared Neighborhood Hits	14
SwissProt Accessions	Q6TAC4, O70409	Gene names	V2r1b
Domain Architecture	No domain graphic available
Description	Vomeronasal type-2 receptor 1b precursor (Putative pheromone receptor V2R1b).

GPC6A_HUMAN
NC score	0.133560 (rank : 23)	θ value	θ > 10 (rank : 87)
Query Neighborhood Hits	82	Target Neighborhood Hits	53	Shared Neighborhood Hits	14
SwissProt Accessions	Q5T6X5, Q6JK43, Q6JK44, Q8NGU8, Q8NHZ9, Q8TDT6	Gene names	GPRC6A, GPCR33
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor family C group 6 member A precursor (hGPRC6A) (G-protein coupled receptor 33) (hGPCR33).

GPC6A_MOUSE
NC score	0.132514 (rank : 24)	θ value	θ > 10 (rank : 88)
Query Neighborhood Hits	82	Target Neighborhood Hits	57	Shared Neighborhood Hits	14
SwissProt Accessions	Q8K4Z6, Q5DK51, Q5DK52	Gene names	Gprc6a
Domain Architecture	No domain graphic available
Description	G-protein coupled receptor family C group 6 member A precursor.

TS1R1_HUMAN
NC score	0.132284 (rank : 25)	θ value	θ > 10 (rank : 91)
Query Neighborhood Hits	82	Target Neighborhood Hits	72	Shared Neighborhood Hits	15
SwissProt Accessions	Q7RTX1, Q8NGZ7, Q8TDJ7, Q8TDJ8, Q8TDJ9, Q8TDK0	Gene names	TAS1R1, GPR70, T1R1, TR1
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 1 precursor (G-protein coupled receptor 70) (Gm148).

TS1R2_MOUSE
NC score	0.129778 (rank : 26)	θ value	θ > 10 (rank : 94)
Query Neighborhood Hits	82	Target Neighborhood Hits	69	Shared Neighborhood Hits	15
SwissProt Accessions	Q925I4, Q923J8	Gene names	Tas1r2, Gpr71, T1r2, Tr2
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 2 precursor (G-protein coupled receptor 71) (Sweet taste receptor T1R2).

TS1R2_HUMAN
NC score	0.127505 (rank : 27)	θ value	θ > 10 (rank : 93)
Query Neighborhood Hits	82	Target Neighborhood Hits	48	Shared Neighborhood Hits	14
SwissProt Accessions	Q8TE23, Q5TZ19	Gene names	TAS1R2, GPR71, T1R2, TR2
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 2 precursor (G-protein coupled receptor 71) (Sweet taste receptor T1R2).

TS1R1_MOUSE
NC score	0.127385 (rank : 28)	θ value	θ > 10 (rank : 92)
Query Neighborhood Hits	82	Target Neighborhood Hits	57	Shared Neighborhood Hits	15
SwissProt Accessions	Q99PG6, Q6NS58, Q923J9, Q925I5, Q99PG5	Gene names	Tas1r1, Gpr70, T1r1, Tr1
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 1 precursor (G-protein coupled receptor 70).

TS1R3_MOUSE
NC score	0.126021 (rank : 29)	θ value	θ > 10 (rank : 96)
Query Neighborhood Hits	82	Target Neighborhood Hits	49	Shared Neighborhood Hits	14
SwissProt Accessions	Q925D8, Q91VA4, Q923K0, Q925A4, Q925D9	Gene names	Tas1r3, Sac, T1r3, Tr3
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 3 precursor (Sweet taste receptor T1R3) (Saccharin preference protein).

TS1R3_HUMAN
NC score	0.124727 (rank : 30)	θ value	θ > 10 (rank : 95)
Query Neighborhood Hits	82	Target Neighborhood Hits	46	Shared Neighborhood Hits	14
SwissProt Accessions	Q7RTX0, Q5TA49, Q8NGW9	Gene names	TAS1R3, T1R3, TR3
Domain Architecture	No domain graphic available
Description	Taste receptor type 1 member 3 precursor (Sweet taste receptor T1R3).

GP156_HUMAN
NC score	0.124133 (rank : 31)	θ value	0.163984 (rank : 21)
Query Neighborhood Hits	82	Target Neighborhood Hits	84	Shared Neighborhood Hits	11
SwissProt Accessions	Q8NFN8, Q86SN6	Gene names	GPR156, GABABL, PGR28
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 156 (GABAB-related G-protein coupled receptor) (G-protein coupled receptor PGR28).

GABR1_MOUSE
NC score	0.095106 (rank : 32)	θ value	θ > 10 (rank : 84)
Query Neighborhood Hits	82	Target Neighborhood Hits	139	Shared Neighborhood Hits	17
SwissProt Accessions	Q9WV18, Q9WU48, Q9WV15, Q9WV16, Q9WV17	Gene names	Gabbr1
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

GABR1_HUMAN
NC score	0.094516 (rank : 33)	θ value	θ > 10 (rank : 83)
Query Neighborhood Hits	82	Target Neighborhood Hits	142	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UBS5, O95375, O95468, O95975, O96022, Q86W60, Q9UQQ0	Gene names	GABBR1, GPRC3A
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

CBP_HUMAN
NC score	0.080621 (rank : 34)	θ value	0.0736092 (rank : 20)
Query Neighborhood Hits	82	Target Neighborhood Hits	941	Shared Neighborhood Hits	13
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CBP_MOUSE
NC score	0.076919 (rank : 35)	θ value	0.0252991 (rank : 16)
Query Neighborhood Hits	82	Target Neighborhood Hits	1051	Shared Neighborhood Hits	13
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

GPC5B_MOUSE
NC score	0.060466 (rank : 36)	θ value	θ > 10 (rank : 86)
Query Neighborhood Hits	82	Target Neighborhood Hits	33	Shared Neighborhood Hits	13
SwissProt Accessions	Q923Z0, Q8CCV3	Gene names	Gprc5b, Raig2
Domain Architecture
Description	G-protein coupled receptor family C group 5 member B precursor (Retinoic acid-induced gene 2 protein) (RAIG-2).

GPC5B_HUMAN
NC score	0.057609 (rank : 37)	θ value	θ > 10 (rank : 85)
Query Neighborhood Hits	82	Target Neighborhood Hits	28	Shared Neighborhood Hits	13
SwissProt Accessions	Q9NZH0, O75205, Q8NBZ8	Gene names	GPRC5B, RAIG2
Domain Architecture
Description	G-protein coupled receptor family C group 5 member B precursor (Retinoic acid-induced gene 2 protein) (RAIG-2) (A-69G12.1).

IF2P_HUMAN
NC score	0.051545 (rank : 38)	θ value	0.0563607 (rank : 18)
Query Neighborhood Hits	82	Target Neighborhood Hits	889	Shared Neighborhood Hits	17
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

CENPC_MOUSE
NC score	0.049936 (rank : 39)	θ value	0.21417 (rank : 23)
Query Neighborhood Hits	82	Target Neighborhood Hits	154	Shared Neighborhood Hits	5
SwissProt Accessions	P49452	Gene names	Cenpc1, Cenpc
Domain Architecture	No domain graphic available
Description	Centromere protein C 1 (CENP-C) (Centromere autoantigen C).

FBN1_MOUSE
NC score	0.048626 (rank : 40)	θ value	0.365318 (rank : 29)
Query Neighborhood Hits	82	Target Neighborhood Hits	563	Shared Neighborhood Hits	22
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

FBN2_HUMAN
NC score	0.048496 (rank : 41)	θ value	0.47712 (rank : 30)
Query Neighborhood Hits	82	Target Neighborhood Hits	560	Shared Neighborhood Hits	20
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN1_HUMAN
NC score	0.048451 (rank : 42)	θ value	0.279714 (rank : 26)
Query Neighborhood Hits	82	Target Neighborhood Hits	557	Shared Neighborhood Hits	20
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

FBN2_MOUSE
NC score	0.047925 (rank : 43)	θ value	1.06291 (rank : 39)
Query Neighborhood Hits	82	Target Neighborhood Hits	549	Shared Neighborhood Hits	20
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

NIPBL_HUMAN
NC score	0.044818 (rank : 44)	θ value	0.21417 (rank : 24)
Query Neighborhood Hits	82	Target Neighborhood Hits	1311	Shared Neighborhood Hits	21
SwissProt Accessions	Q6KC79, Q6KCD6, Q6N080, Q6ZT92, Q7Z2E6, Q8N4M5, Q9Y6Y3, Q9Y6Y4	Gene names	NIPBL, IDN3
Domain Architecture	No domain graphic available
Description	Nipped-B-like protein (Delangin) (SCC2 homolog).

PHF20_HUMAN
NC score	0.041473 (rank : 45)	θ value	1.38821 (rank : 44)
Query Neighborhood Hits	82	Target Neighborhood Hits	394	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BVI0, Q5JWY9, Q9BWV4, Q9BXA3, Q9BZW3, Q9H421, Q9H4J6, Q9NZ22	Gene names	PHF20, C20orf104, GLEA2, HCA58, NZF, TZP
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58) (Glioma-expressed antigen 2) (Transcription factor TZP) (Novel zinc finger protein).

FBN3_HUMAN
NC score	0.041070 (rank : 46)	θ value	8.99809 (rank : 77)
Query Neighborhood Hits	82	Target Neighborhood Hits	543	Shared Neighborhood Hits	20
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

PHF20_MOUSE
NC score	0.040874 (rank : 47)	θ value	1.06291 (rank : 41)
Query Neighborhood Hits	82	Target Neighborhood Hits	513	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BLG0, Q8BMA2, Q8BYR4, Q921N1	Gene names	Phf20, Hca58
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58 homolog).

LUZP1_MOUSE
NC score	0.040498 (rank : 48)	θ value	0.0563607 (rank : 19)
Query Neighborhood Hits	82	Target Neighborhood Hits	940	Shared Neighborhood Hits	13
SwissProt Accessions	Q8R4U7, Q3UV18, Q7TS71, Q8BQW1, Q99NG3, Q9CSL6	Gene names	Luzp1, Luzp
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1 (Leucine zipper motif-containing protein).

MINT_MOUSE
NC score	0.039833 (rank : 49)	θ value	0.62314 (rank : 31)
Query Neighborhood Hits	82	Target Neighborhood Hits	1514	Shared Neighborhood Hits	26
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

FBLN2_HUMAN
NC score	0.039581 (rank : 50)	θ value	0.813845 (rank : 34)
Query Neighborhood Hits	82	Target Neighborhood Hits	392	Shared Neighborhood Hits	19
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

NELL1_HUMAN
NC score	0.037832 (rank : 51)	θ value	0.813845 (rank : 38)
Query Neighborhood Hits	82	Target Neighborhood Hits	451	Shared Neighborhood Hits	19
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

NOTC1_MOUSE
NC score	0.036194 (rank : 52)	θ value	0.62314 (rank : 32)
Query Neighborhood Hits	82	Target Neighborhood Hits	916	Shared Neighborhood Hits	20
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

FBLN1_MOUSE
NC score	0.035583 (rank : 53)	θ value	8.99809 (rank : 76)
Query Neighborhood Hits	82	Target Neighborhood Hits	329	Shared Neighborhood Hits	19
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

ATRX_MOUSE
NC score	0.035025 (rank : 54)	θ value	5.27518 (rank : 66)
Query Neighborhood Hits	82	Target Neighborhood Hits	682	Shared Neighborhood Hits	14
SwissProt Accessions	Q61687	Gene names	Atrx, Hp1bp2, Xnp
Domain Architecture
Description	Transcriptional regulator ATRX (EC 3.6.1.-) (ATP-dependent helicase ATRX) (X-linked nuclear protein) (Heterochromatin protein 2) (HP1 alpha-interacting protein) (HP1-BP38 protein).

NOTC2_MOUSE
NC score	0.032898 (rank : 55)	θ value	3.0926 (rank : 60)
Query Neighborhood Hits	82	Target Neighborhood Hits	1069	Shared Neighborhood Hits	24
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

ITPR3_HUMAN
NC score	0.032764 (rank : 56)	θ value	0.813845 (rank : 35)
Query Neighborhood Hits	82	Target Neighborhood Hits	114	Shared Neighborhood Hits	7
SwissProt Accessions	Q14573, Q14649	Gene names	ITPR3
Domain Architecture
Description	Inositol 1,4,5-trisphosphate receptor type 3 (Type 3 inositol 1,4,5- trisphosphate receptor) (Type 3 InsP3 receptor) (IP3 receptor isoform 3) (InsP3R3).

ITPR3_MOUSE
NC score	0.032412 (rank : 57)	θ value	0.813845 (rank : 36)
Query Neighborhood Hits	82	Target Neighborhood Hits	105	Shared Neighborhood Hits	4
SwissProt Accessions	P70227, Q5DWM4, Q8CED5, Q91Z08	Gene names	Itpr3
Domain Architecture	No domain graphic available
Description	Inositol 1,4,5-trisphosphate receptor type 3 (Type 3 inositol 1,4,5- trisphosphate receptor) (Type 3 InsP3 receptor) (IP3 receptor isoform 3) (InsP3R3).

LTB1L_HUMAN
NC score	0.031907 (rank : 58)	θ value	8.99809 (rank : 78)
Query Neighborhood Hits	82	Target Neighborhood Hits	553	Shared Neighborhood Hits	22
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
NC score	0.031368 (rank : 59)	θ value	8.99809 (rank : 79)
Query Neighborhood Hits	82	Target Neighborhood Hits	502	Shared Neighborhood Hits	20
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTBP3_HUMAN
NC score	0.031049 (rank : 60)	θ value	8.99809 (rank : 80)
Query Neighborhood Hits	82	Target Neighborhood Hits	502	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

RGL2_MOUSE
NC score	0.029466 (rank : 61)	θ value	0.279714 (rank : 27)
Query Neighborhood Hits	82	Target Neighborhood Hits	51	Shared Neighborhood Hits	2
SwissProt Accessions	Q61193, Q9QUJ2	Gene names	Rgl2, Rab2l, Rlf
Domain Architecture
Description	Ral guanine nucleotide dissociation stimulator-like 2 (RalGDS-like factor) (RAS-associated protein RAB2L).

EMR1_MOUSE
NC score	0.028959 (rank : 62)	θ value	1.38821 (rank : 43)
Query Neighborhood Hits	82	Target Neighborhood Hits	349	Shared Neighborhood Hits	18
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

RENT2_HUMAN
NC score	0.028879 (rank : 63)	θ value	2.36792 (rank : 55)
Query Neighborhood Hits	82	Target Neighborhood Hits	618	Shared Neighborhood Hits	11
SwissProt Accessions	Q9HAU5, Q8N8U1, Q9H1J2, Q9NWL1, Q9P2D9, Q9Y4M9	Gene names	UPF2, KIAA1408, RENT2
Domain Architecture	No domain graphic available
Description	Regulator of nonsense transcripts 2 (Nonsense mRNA reducing factor 2) (Up-frameshift suppressor 2 homolog) (hUpf2).

SETX_HUMAN
NC score	0.028385 (rank : 64)	θ value	1.06291 (rank : 42)
Query Neighborhood Hits	82	Target Neighborhood Hits	368	Shared Neighborhood Hits	8
SwissProt Accessions	Q7Z333, O75120, Q3KQX4, Q68DW5, Q6AZD7, Q7Z3J6, Q8WX33, Q9H9D1, Q9NVP9	Gene names	SETX, ALS4, KIAA0625, SCAR1
Domain Architecture
Description	Probable helicase senataxin (EC 3.6.1.-) (SEN1 homolog).

RIOK2_HUMAN
NC score	0.028201 (rank : 65)	θ value	1.81305 (rank : 52)
Query Neighborhood Hits	82	Target Neighborhood Hits	125	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BVS4, Q9NUT0	Gene names	RIOK2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase RIO2 (EC 2.7.11.1) (RIO kinase 2).

AP2A_HUMAN
NC score	0.027907 (rank : 66)	θ value	1.81305 (rank : 48)
Query Neighborhood Hits	82	Target Neighborhood Hits	36	Shared Neighborhood Hits	4
SwissProt Accessions	P05549, Q13777	Gene names	TFAP2A, AP2TF, TFAP2
Domain Architecture
Description	Transcription factor AP-2 alpha (AP2-alpha) (Activating enhancer- binding protein 2 alpha) (AP-2 transcription factor) (Activator protein 2) (AP-2).

HMCN1_HUMAN
NC score	0.027838 (rank : 67)	θ value	6.88961 (rank : 71)
Query Neighborhood Hits	82	Target Neighborhood Hits	983	Shared Neighborhood Hits	21
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

AP2A_MOUSE
NC score	0.027692 (rank : 68)	θ value	1.81305 (rank : 49)
Query Neighborhood Hits	82	Target Neighborhood Hits	36	Shared Neighborhood Hits	4
SwissProt Accessions	P34056, Q60740, Q60741, Q60742, Q60743, Q62067, Q62068, Q62069, Q91VX0, Q9CRY4	Gene names	Tfap2a, Ap2tf, Tcfap2a
Domain Architecture
Description	Transcription factor AP-2 alpha (AP2-alpha) (Activating enhancer- binding protein 2 alpha) (Activator protein 2) (AP-2).

LIMA1_HUMAN
NC score	0.027063 (rank : 69)	θ value	2.36792 (rank : 54)
Query Neighborhood Hits	82	Target Neighborhood Hits	309	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UHB6, Q2TAN7, Q9BVF2, Q9H8J1, Q9HBN5, Q9NX96, Q9NXC3, Q9NXU6, Q9P0H8, Q9UHB5	Gene names	LIMA1, EPLIN, SREBP3
Domain Architecture
Description	LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm).

EMR1_HUMAN
NC score	0.026106 (rank : 70)	θ value	8.99809 (rank : 75)
Query Neighborhood Hits	82	Target Neighborhood Hits	382	Shared Neighborhood Hits	18
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

REPS1_MOUSE
NC score	0.025550 (rank : 71)	θ value	1.81305 (rank : 51)
Query Neighborhood Hits	82	Target Neighborhood Hits	204	Shared Neighborhood Hits	4
SwissProt Accessions	O54916, Q8C9J9, Q99LR8	Gene names	Reps1
Domain Architecture
Description	RalBP1-associated Eps domain-containing protein 1 (RalBP1-interacting protein 1).

AIM1_HUMAN
NC score	0.024998 (rank : 72)	θ value	5.27518 (rank : 65)
Query Neighborhood Hits	82	Target Neighborhood Hits	247	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y4K1, O00296, Q5VWJ2	Gene names	AIM1
Domain Architecture
Description	Absent in melanoma 1 protein.

RXINP_HUMAN
NC score	0.024971 (rank : 73)	θ value	2.36792 (rank : 56)
Query Neighborhood Hits	82	Target Neighborhood Hits	87	Shared Neighborhood Hits	2
SwissProt Accessions	Q96RL1, Q5XKQ1, Q7Z3W7, Q8N5B9, Q9BZR1, Q9BZR5, Q9UHX7	Gene names	RXRIP110, RAP80
Domain Architecture	No domain graphic available
Description	Retinoid X receptor-interacting protein 110 (Receptor-associated protein 80) (Nuclear zinc finger protein RAP80).

RAI1_MOUSE
NC score	0.024119 (rank : 74)	θ value	1.38821 (rank : 45)
Query Neighborhood Hits	82	Target Neighborhood Hits	344	Shared Neighborhood Hits	5
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

TSC2_HUMAN
NC score	0.022958 (rank : 75)	θ value	4.03905 (rank : 63)
Query Neighborhood Hits	82	Target Neighborhood Hits	59	Shared Neighborhood Hits	4
SwissProt Accessions	P49815, O75275, Q8TAZ1	Gene names	TSC2
Domain Architecture
Description	Tuberin (Tuberous sclerosis 2 protein).

TITIN_HUMAN
NC score	0.022268 (rank : 76)	θ value	0.000461057 (rank : 8)
Query Neighborhood Hits	82	Target Neighborhood Hits	2923	Shared Neighborhood Hits	24
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

NCOR2_HUMAN
NC score	0.021111 (rank : 77)	θ value	6.88961 (rank : 73)
Query Neighborhood Hits	82	Target Neighborhood Hits	870	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y618, O00613, O15416, Q13354, Q9Y5U0	Gene names	NCOR2, CTG26
Domain Architecture
Description	Nuclear receptor corepressor 2 (N-CoR2) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (SMRTe) (Thyroid-, retinoic-acid-receptor-associated corepressor) (T3 receptor- associating factor) (TRAC) (CTG repeat protein 26) (SMAP270).

TNR6A_HUMAN
NC score	0.019531 (rank : 78)	θ value	5.27518 (rank : 68)
Query Neighborhood Hits	82	Target Neighborhood Hits	343	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NDV7, O15408, Q658L5, Q6NVB5, Q8NEZ0, Q8TBT8, Q8TCR0, Q9NV59, Q9P268	Gene names	TNRC6A, CAGH26, KIAA1460, TNRC6
Domain Architecture	No domain graphic available
Description	Trinucleotide repeat-containing gene 6A protein (CAG repeat protein 26) (Glycine-tryptophan protein of 182 kDa) (GW182 autoantigen) (Protein GW1) (EMSY interactor protein).

TOPB1_HUMAN
NC score	0.019406 (rank : 79)	θ value	3.0926 (rank : 61)
Query Neighborhood Hits	82	Target Neighborhood Hits	82	Shared Neighborhood Hits	3
SwissProt Accessions	Q92547, Q7LGC1, Q9UEB9	Gene names	TOPBP1, KIAA0259
Domain Architecture	No domain graphic available
Description	DNA topoisomerase 2-binding protein 1 (DNA topoisomerase II-binding protein 1) (DNA topoisomerase IIbeta-binding protein 1) (TopBP1).

TRPC5_MOUSE
NC score	0.017862 (rank : 80)	θ value	0.62314 (rank : 33)
Query Neighborhood Hits	82	Target Neighborhood Hits	124	Shared Neighborhood Hits	5
SwissProt Accessions	Q9QX29, Q61059, Q9QWT1, Q9R0D4	Gene names	Trpc5, Trp5, Trrp5
Domain Architecture
Description	Short transient receptor potential channel 5 (TrpC5) (Transient receptor protein 5) (Mtrp5) (trp-related protein 5) (Capacitative calcium entry channel 2) (CCE2).

ABCA9_MOUSE
NC score	0.017610 (rank : 81)	θ value	3.0926 (rank : 58)
Query Neighborhood Hits	82	Target Neighborhood Hits	107	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K449, Q8C114	Gene names	Abca9
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 9.

ABCA9_HUMAN
NC score	0.016732 (rank : 82)	θ value	5.27518 (rank : 64)
Query Neighborhood Hits	82	Target Neighborhood Hits	111	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IUA7, Q6P655, Q8N2S4, Q8WWZ5, Q96MD8	Gene names	ABCA9
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 9.

TACC2_MOUSE
NC score	0.016499 (rank : 83)	θ value	2.36792 (rank : 57)
Query Neighborhood Hits	82	Target Neighborhood Hits	774	Shared Neighborhood Hits	13
SwissProt Accessions	Q9JJG0	Gene names	Tacc2
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 2.

FRAS1_HUMAN
NC score	0.016315 (rank : 84)	θ value	6.88961 (rank : 70)
Query Neighborhood Hits	82	Target Neighborhood Hits	759	Shared Neighborhood Hits	19
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

ABCA8_HUMAN
NC score	0.015720 (rank : 85)	θ value	6.88961 (rank : 69)
Query Neighborhood Hits	82	Target Neighborhood Hits	113	Shared Neighborhood Hits	5
SwissProt Accessions	O94911, Q86WW0	Gene names	ABCA8, KIAA0822
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 8.

EDEM3_HUMAN
NC score	0.015715 (rank : 86)	θ value	3.0926 (rank : 59)
Query Neighborhood Hits	82	Target Neighborhood Hits	92	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BZQ6, Q5TEZ0, Q9HCW1, Q9UFV7	Gene names	EDEM3, C1orf22
Domain Architecture
Description	ER degradation-enhancing alpha-mannosidase-like 3.

CENPE_HUMAN
NC score	0.012250 (rank : 87)	θ value	0.279714 (rank : 25)
Query Neighborhood Hits	82	Target Neighborhood Hits	2060	Shared Neighborhood Hits	14
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

ABR_HUMAN
NC score	0.011912 (rank : 88)	θ value	1.81305 (rank : 47)
Query Neighborhood Hits	82	Target Neighborhood Hits	166	Shared Neighborhood Hits	3
SwissProt Accessions	Q12979, Q13693, Q13694	Gene names	ABR
Domain Architecture
Description	Active breakpoint cluster region-related protein.

ST5_MOUSE
NC score	0.010806 (rank : 89)	θ value	8.99809 (rank : 82)
Query Neighborhood Hits	82	Target Neighborhood Hits	126	Shared Neighborhood Hits	5
SwissProt Accessions	Q924W7, Q78H54, Q8K2P3, Q924W8	Gene names	St5, Dennd2b
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity 5 (DENN domain-containing protein 2B).

CE290_HUMAN
NC score	0.010727 (rank : 90)	θ value	4.03905 (rank : 62)
Query Neighborhood Hits	82	Target Neighborhood Hits	1553	Shared Neighborhood Hits	14
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

TBC10_MOUSE
NC score	0.009413 (rank : 91)	θ value	6.88961 (rank : 74)
Query Neighborhood Hits	82	Target Neighborhood Hits	94	Shared Neighborhood Hits	2
SwissProt Accessions	P58802	Gene names	Tbc1d10a, Epi64, Tbc1d10
Domain Architecture
Description	TBC1 domain family member 10A (EBP50-PDX interactor of 64 kDa) (EPI64 protein).

MTMR5_HUMAN
NC score	0.008799 (rank : 92)	θ value	6.88961 (rank : 72)
Query Neighborhood Hits	82	Target Neighborhood Hits	141	Shared Neighborhood Hits	3
SwissProt Accessions	O95248, O60228, Q5JXD8, Q5PPM2, Q96GR9, Q9UGB8	Gene names	SBF1, MTMR5
Domain Architecture
Description	SET-binding factor 1 (Sbf1) (Myotubularin-related protein 5).

NBEA_HUMAN
NC score	0.008713 (rank : 93)	θ value	8.99809 (rank : 81)
Query Neighborhood Hits	82	Target Neighborhood Hits	186	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NFP9, Q9HCM8, Q9NSU1, Q9NW98, Q9Y6J1	Gene names	NBEA, BCL8B, KIAA1544, LYST2
Domain Architecture
Description	Protein neurobeachin (Lysosomal-trafficking regulator 2) (Protein BCL8B).

Z297B_MOUSE
NC score	0.006485 (rank : 94)	θ value	1.38821 (rank : 46)
Query Neighborhood Hits	82	Target Neighborhood Hits	806	Shared Neighborhood Hits	5
SwissProt Accessions	Q9DAI4	Gene names	Znf297b, Kiaa0414, Zfp297b
Domain Architecture
Description	Zinc finger protein 297B.

G109B_HUMAN
NC score	0.006178 (rank : 95)	θ value	1.81305 (rank : 50)
Query Neighborhood Hits	82	Target Neighborhood Hits	579	Shared Neighborhood Hits	3
SwissProt Accessions	P49019, Q8NGE4	Gene names	GPR109B
Domain Architecture
Description	Nicotinic acid receptor 2 (G-protein coupled receptor 109B) (G-protein coupled receptor HM74) (G-protein coupled receptor HM74B).

Z297B_HUMAN
NC score	0.005968 (rank : 96)	θ value	1.81305 (rank : 53)
Query Neighborhood Hits	82	Target Neighborhood Hits	792	Shared Neighborhood Hits	4
SwissProt Accessions	O43298	Gene names	ZNF297B, KIAA0414, ZBTB22B
Domain Architecture
Description	Zinc finger protein 297B (ZnF-x) (Zinc finger and BTB domain- containing protein 22B).

ZN236_HUMAN
NC score	0.003914 (rank : 97)	θ value	0.279714 (rank : 28)
Query Neighborhood Hits	82	Target Neighborhood Hits	844	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UL36, Q9UL37	Gene names	ZNF236
Domain Architecture	No domain graphic available
Description	Zinc finger protein 236.

O51I1_HUMAN
NC score	-0.000108 (rank : 98)	θ value	5.27518 (rank : 67)
Query Neighborhood Hits	82	Target Neighborhood Hits	756	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H343, Q6IF33	Gene names	OR51I1
Domain Architecture
Description	Olfactory receptor 51I1 (Odorant receptor HOR5'beta11) (Olfactory receptor OR11-39).