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Network neighborhood for query Sequence : EDEM3_HUMAN

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EDEM3_HUMAN
SwissProt Accessions	Q9BZQ6, Q5TEZ0, Q9HCW1, Q9UFV7	Gene names	EDEM3, C1orf22
Domain Architecture
Description	ER degradation-enhancing alpha-mannosidase-like 3.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

EDEM3_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	92	Target Neighborhood Hits	92	Shared Neighborhood Hits	92
SwissProt Accessions	Q9BZQ6, Q5TEZ0, Q9HCW1, Q9UFV7	Gene names	EDEM3, C1orf22
Domain Architecture
Description	ER degradation-enhancing alpha-mannosidase-like 3.

EDEM1_HUMAN
θ value	1.43912e-106 (rank : 2)	NC score	0.929976 (rank : 2)
Query Neighborhood Hits	92	Target Neighborhood Hits	24	Shared Neighborhood Hits	11
SwissProt Accessions	Q92611	Gene names	EDEM1, EDEM, KIAA0212
Domain Architecture
Description	ER degradation-enhancing alpha-mannosidase-like 1.

EDEM1_MOUSE
θ value	1.43912e-106 (rank : 3)	NC score	0.928802 (rank : 3)
Query Neighborhood Hits	92	Target Neighborhood Hits	23	Shared Neighborhood Hits	11
SwissProt Accessions	Q925U4	Gene names	Edem1, Edem
Domain Architecture
Description	ER degradation-enhancing alpha-mannosidase-like 1.

EDEM2_HUMAN
θ value	2.47191e-82 (rank : 4)	NC score	0.927857 (rank : 4)
Query Neighborhood Hits	92	Target Neighborhood Hits	16	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BV94, Q6IA89, Q6UWZ4, Q9H4U0, Q9H886, Q9NTL9, Q9NVE6	Gene names	EDEM2, C20orf31, C20orf49
Domain Architecture
Description	ER degradation-enhancing alpha-mannosidase-like 2 precursor.

MA1B1_HUMAN
θ value	2.25659e-51 (rank : 5)	NC score	0.850558 (rank : 5)
Query Neighborhood Hits	92	Target Neighborhood Hits	125	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UKM7, Q5VSG3, Q9BRS9, Q9Y5K7	Gene names	MAN1B1
Domain Architecture
Description	Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase (EC 3.2.1.113) (ER alpha-1,2-mannosidase) (Mannosidase alpha class 1B member 1) (Man9GlcNAc2-specific-processing alpha-mannosidase).

MA1A1_HUMAN
θ value	3.98324e-48 (rank : 6)	NC score	0.832578 (rank : 6)
Query Neighborhood Hits	92	Target Neighborhood Hits	26	Shared Neighborhood Hits	10
SwissProt Accessions	P33908, Q9NU44, Q9UJI3	Gene names	MAN1A1
Domain Architecture
Description	Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA (EC 3.2.1.113) (Processing alpha-1,2-mannosidase IA) (Alpha-1,2-mannosidase IA) (Mannosidase alpha class 1A member 1) (Man(9)-alpha-mannosidase) (Man9-mannosidase).

MA1A1_MOUSE
θ value	7.51208e-47 (rank : 7)	NC score	0.831835 (rank : 7)
Query Neighborhood Hits	92	Target Neighborhood Hits	32	Shared Neighborhood Hits	10
SwissProt Accessions	P45700	Gene names	Man1a1, Man1a
Domain Architecture
Description	Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA (EC 3.2.1.113) (Processing alpha-1,2-mannosidase IA) (Alpha-1,2-mannosidase IA) (Mannosidase alpha class 1A member 1) (Man(9)-alpha-mannosidase) (Man9-mannosidase).

MA1A2_HUMAN
θ value	2.86122e-38 (rank : 8)	NC score	0.824776 (rank : 9)
Query Neighborhood Hits	92	Target Neighborhood Hits	31	Shared Neighborhood Hits	12
SwissProt Accessions	O60476, Q9H510	Gene names	MAN1A2, MAN1B
Domain Architecture
Description	Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB (EC 3.2.1.113) (Processing alpha-1,2-mannosidase IB) (Alpha-1,2-mannosidase IB) (Mannosidase alpha class 1A member 2).

MA1A2_MOUSE
θ value	9.20422e-37 (rank : 9)	NC score	0.821882 (rank : 10)
Query Neighborhood Hits	92	Target Neighborhood Hits	31	Shared Neighborhood Hits	10
SwissProt Accessions	P39098, Q5SUY6, Q5SUY7, Q60599, Q9CUY9	Gene names	Man1a2, Man1b
Domain Architecture
Description	Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB (EC 3.2.1.113) (Processing alpha-1,2-mannosidase IB) (Alpha-1,2-mannosidase IB) (Mannosidase alpha class 1A member 2).

MA1C1_HUMAN
θ value	3.86705e-35 (rank : 10)	NC score	0.829305 (rank : 8)
Query Neighborhood Hits	92	Target Neighborhood Hits	21	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NR34, Q9Y545	Gene names	MAN1C1, MAN1A3, MAN1C
Domain Architecture
Description	Mannosyl-oligosaccharide 1,2-alpha-mannosidase IC (EC 3.2.1.113) (Processing alpha-1,2-mannosidase IC) (Alpha-1,2-mannosidase IC) (Mannosidase alpha class 1C member 1) (HMIC).

PAP21_HUMAN
θ value	2.88788e-06 (rank : 11)	NC score	0.200445 (rank : 12)
Query Neighborhood Hits	92	Target Neighborhood Hits	11	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BSG0	Gene names	PAP21, C2orf7
Domain Architecture	No domain graphic available
Description	Protease-associated domain-containing protein of 21 kDa precursor (hPAP21).

PAP21_MOUSE
θ value	2.88788e-06 (rank : 12)	NC score	0.200492 (rank : 11)
Query Neighborhood Hits	92	Target Neighborhood Hits	11	Shared Neighborhood Hits	11
SwissProt Accessions	Q9D9N8	Gene names	Pap21
Domain Architecture	No domain graphic available
Description	Protease-associated domain-containing protein of 21 kDa precursor.

RNF13_MOUSE
θ value	0.00102713 (rank : 13)	NC score	0.113956 (rank : 13)
Query Neighborhood Hits	92	Target Neighborhood Hits	164	Shared Neighborhood Hits	12
SwissProt Accessions	O54965, O54966	Gene names	Rnf13, Rzf
Domain Architecture
Description	RING finger protein 13.

SSH2_HUMAN
θ value	0.00102713 (rank : 14)	NC score	0.042511 (rank : 39)
Query Neighborhood Hits	92	Target Neighborhood Hits	140	Shared Neighborhood Hits	3
SwissProt Accessions	Q76I76, Q8TDB5, Q8WYL1, Q8WYL2, Q96F40, Q96H36, Q9C0D8	Gene names	SSH2, KIAA1725, SSH2L
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 2 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-2L) (hSSH-2L).

RN167_HUMAN
θ value	0.00228821 (rank : 15)	NC score	0.108891 (rank : 14)
Query Neighborhood Hits	92	Target Neighborhood Hits	157	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H6Y7, Q6XYE0, Q8NDC1, Q9Y3V1	Gene names	RNF167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

LEO1_MOUSE
θ value	0.00298849 (rank : 16)	NC score	0.071940 (rank : 22)
Query Neighborhood Hits	92	Target Neighborhood Hits	946	Shared Neighborhood Hits	39
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

RNF13_HUMAN
θ value	0.00665767 (rank : 17)	NC score	0.108468 (rank : 15)
Query Neighborhood Hits	92	Target Neighborhood Hits	147	Shared Neighborhood Hits	10
SwissProt Accessions	O43567	Gene names	RNF13, RZF
Domain Architecture
Description	RING finger protein 13.

DMP1_MOUSE
θ value	0.00869519 (rank : 18)	NC score	0.084328 (rank : 18)
Query Neighborhood Hits	92	Target Neighborhood Hits	498	Shared Neighborhood Hits	35
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

RN167_MOUSE
θ value	0.0148317 (rank : 19)	NC score	0.106663 (rank : 16)
Query Neighborhood Hits	92	Target Neighborhood Hits	157	Shared Neighborhood Hits	11
SwissProt Accessions	Q91XF4, Q3U4S5	Gene names	Rnf167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

PSL1_MOUSE
θ value	0.0252991 (rank : 20)	NC score	0.078480 (rank : 19)
Query Neighborhood Hits	92	Target Neighborhood Hits	32	Shared Neighborhood Hits	10
SwissProt Accessions	Q3TD49, Q3TLQ8, Q3UG60, Q80VZ6	Gene names	Sppl2b
Domain Architecture	No domain graphic available
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b).

ANR21_HUMAN
θ value	0.0330416 (rank : 21)	NC score	0.033948 (rank : 47)
Query Neighborhood Hits	92	Target Neighborhood Hits	864	Shared Neighborhood Hits	27
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

IWS1_HUMAN
θ value	0.0330416 (rank : 22)	NC score	0.055312 (rank : 29)
Query Neighborhood Hits	92	Target Neighborhood Hits	1241	Shared Neighborhood Hits	40
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

ABTAP_MOUSE
θ value	0.0563607 (rank : 23)	NC score	0.057635 (rank : 26)
Query Neighborhood Hits	92	Target Neighborhood Hits	381	Shared Neighborhood Hits	23
SwissProt Accessions	Q3V1V3	Gene names	Abtap
Domain Architecture	No domain graphic available
Description	ABT1-associated protein.

POT15_HUMAN
θ value	0.0563607 (rank : 24)	NC score	0.033451 (rank : 48)
Query Neighborhood Hits	92	Target Neighborhood Hits	893	Shared Neighborhood Hits	29
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

MYH10_HUMAN
θ value	0.0961366 (rank : 25)	NC score	0.012761 (rank : 78)
Query Neighborhood Hits	92	Target Neighborhood Hits	1620	Shared Neighborhood Hits	22
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

PSL2_HUMAN
θ value	0.0961366 (rank : 26)	NC score	0.071494 (rank : 23)
Query Neighborhood Hits	92	Target Neighborhood Hits	19	Shared Neighborhood Hits	7
SwissProt Accessions	Q8TCT8, Q8TAW1, Q96SZ8	Gene names	SPPL2A, PSL2
Domain Architecture
Description	Signal peptide peptidase-like 2A (EC 3.4.23.-) (Protein SPP-like 2A) (Protein SPPL2a) (Intramembrane protease 3) (IMP3) (Presenilin-like protein 2).

BPTF_HUMAN
θ value	0.125558 (rank : 27)	NC score	0.039164 (rank : 42)
Query Neighborhood Hits	92	Target Neighborhood Hits	786	Shared Neighborhood Hits	32
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

SPRL1_HUMAN
θ value	0.163984 (rank : 28)	NC score	0.054323 (rank : 30)
Query Neighborhood Hits	92	Target Neighborhood Hits	231	Shared Neighborhood Hits	22
SwissProt Accessions	Q14515, Q14800	Gene names	SPARCL1
Domain Architecture
Description	SPARC-like protein 1 precursor (High endothelial venule protein) (Hevin) (MAST 9).

RP1L1_MOUSE
θ value	0.21417 (rank : 29)	NC score	0.050785 (rank : 32)
Query Neighborhood Hits	92	Target Neighborhood Hits	170	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CGM2, Q8K0I4	Gene names	Rp1l1, Rp1hl1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein (Retinitis pigmentosa 1-like protein 1).

TFR1_MOUSE
θ value	0.21417 (rank : 30)	NC score	0.032683 (rank : 49)
Query Neighborhood Hits	92	Target Neighborhood Hits	24	Shared Neighborhood Hits	5
SwissProt Accessions	Q62351, Q61560	Gene names	Tfrc, Trfr
Domain Architecture
Description	Transferrin receptor protein 1 (TfR1) (TR) (TfR) (Trfr) (CD71 antigen).

CB010_HUMAN
θ value	0.279714 (rank : 31)	NC score	0.049939 (rank : 34)
Query Neighborhood Hits	92	Target Neighborhood Hits	130	Shared Neighborhood Hits	5
SwissProt Accessions	Q7Z570, Q6ZN26	Gene names	C2orf10
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C2orf10.

AKA12_HUMAN
θ value	0.365318 (rank : 32)	NC score	0.047679 (rank : 36)
Query Neighborhood Hits	92	Target Neighborhood Hits	825	Shared Neighborhood Hits	30
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

CENPB_MOUSE
θ value	0.365318 (rank : 33)	NC score	0.054028 (rank : 31)
Query Neighborhood Hits	92	Target Neighborhood Hits	163	Shared Neighborhood Hits	16
SwissProt Accessions	P27790	Gene names	Cenpb, Cenp-b
Domain Architecture
Description	Major centromere autoantigen B (Centromere protein B) (CENP-B).

DHX30_HUMAN
θ value	0.365318 (rank : 34)	NC score	0.022605 (rank : 61)
Query Neighborhood Hits	92	Target Neighborhood Hits	43	Shared Neighborhood Hits	3
SwissProt Accessions	Q7L2E3, O94965, Q7Z753, Q96CH4	Gene names	DHX30, KIAA0890
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX30 (EC 3.6.1.-) (DEAH box protein 30).

LEO1_HUMAN
θ value	0.365318 (rank : 35)	NC score	0.065189 (rank : 24)
Query Neighborhood Hits	92	Target Neighborhood Hits	958	Shared Neighborhood Hits	43
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

MIER1_MOUSE
θ value	0.47712 (rank : 36)	NC score	0.048209 (rank : 35)
Query Neighborhood Hits	92	Target Neighborhood Hits	84	Shared Neighborhood Hits	7
SwissProt Accessions	Q5UAK0, Q5UAK1, Q5UAK2, Q5UAK3, Q6ZPL6, Q9D402	Gene names	Mier1, Kiaa1610
Domain Architecture	No domain graphic available
Description	Mesoderm induction early response protein 1 (Mi-er1).

PSL1_HUMAN
θ value	0.47712 (rank : 37)	NC score	0.057333 (rank : 27)
Query Neighborhood Hits	92	Target Neighborhood Hits	650	Shared Neighborhood Hits	13
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

RN133_HUMAN
θ value	0.47712 (rank : 38)	NC score	0.086332 (rank : 17)
Query Neighborhood Hits	92	Target Neighborhood Hits	108	Shared Neighborhood Hits	12
SwissProt Accessions	Q8WVZ7, Q8N7G7	Gene names	RNF133
Domain Architecture	No domain graphic available
Description	RING finger protein 133.

ZHX2_HUMAN
θ value	0.47712 (rank : 39)	NC score	0.021731 (rank : 63)
Query Neighborhood Hits	92	Target Neighborhood Hits	347	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y6X8	Gene names	ZHX2, AFR1, KIAA0854, RAF
Domain Architecture
Description	Zinc fingers and homeoboxes protein 2 (Zinc finger and homeodomain protein 2) (Alpha-fetoprotein regulator 1) (AFP regulator 1) (Regulator of AFP).

DSPP_HUMAN
θ value	0.62314 (rank : 40)	NC score	0.046441 (rank : 37)
Query Neighborhood Hits	92	Target Neighborhood Hits	645	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

MYH10_MOUSE
θ value	0.62314 (rank : 41)	NC score	0.011589 (rank : 79)
Query Neighborhood Hits	92	Target Neighborhood Hits	1612	Shared Neighborhood Hits	24
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYT1_MOUSE
θ value	0.62314 (rank : 42)	NC score	0.032008 (rank : 51)
Query Neighborhood Hits	92	Target Neighborhood Hits	385	Shared Neighborhood Hits	16
SwissProt Accessions	Q8CFC2, O08995, Q8CFH1	Gene names	Myt1, Kiaa0835, Nzf2
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1 (MyT1) (Neural zinc finger factor 2) (NZF-2).

GOLI_HUMAN
θ value	0.813845 (rank : 43)	NC score	0.073448 (rank : 20)
Query Neighborhood Hits	92	Target Neighborhood Hits	137	Shared Neighborhood Hits	15
SwissProt Accessions	Q86XS8, Q641P9, Q6P177, Q7L2U2, Q9P0J9	Gene names	RNF130
Domain Architecture	No domain graphic available
Description	Goliath homolog precursor (RING finger protein 130).

GOLI_MOUSE
θ value	0.813845 (rank : 44)	NC score	0.073419 (rank : 21)
Query Neighborhood Hits	92	Target Neighborhood Hits	134	Shared Neighborhood Hits	15
SwissProt Accessions	Q8VEM1, Q80VL7, Q9QZQ6	Gene names	Rnf130, G1rp
Domain Architecture	No domain graphic available
Description	Goliath homolog precursor (RING finger protein 130) (G1-related zinc finger protein).

CF051_HUMAN
θ value	1.06291 (rank : 45)	NC score	0.050736 (rank : 33)
Query Neighborhood Hits	92	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q969F1	Gene names	C6orf51
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf51.

CHD2_HUMAN
θ value	1.06291 (rank : 46)	NC score	0.016724 (rank : 71)
Query Neighborhood Hits	92	Target Neighborhood Hits	360	Shared Neighborhood Hits	16
SwissProt Accessions	O14647	Gene names	CHD2
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 2 (EC 3.6.1.-) (ATP- dependent helicase CHD2) (CHD-2).

EP15R_MOUSE
θ value	1.06291 (rank : 47)	NC score	0.018957 (rank : 67)
Query Neighborhood Hits	92	Target Neighborhood Hits	1135	Shared Neighborhood Hits	24
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

MIER1_HUMAN
θ value	1.38821 (rank : 48)	NC score	0.044571 (rank : 38)
Query Neighborhood Hits	92	Target Neighborhood Hits	75	Shared Neighborhood Hits	8
SwissProt Accessions	Q8N108, Q5T104, Q6AHY8, Q86TB4, Q8N156, Q8N161, Q8NC37, Q8NES4, Q8NES5, Q8NES6, Q8WWG2, Q9HCG2	Gene names	MIER1, KIAA1610
Domain Architecture	No domain graphic available
Description	Mesoderm induction early response protein 1 (Mi-er1) (hmi-er1) (Early response 1) (Er1).

NSD1_MOUSE
θ value	1.38821 (rank : 49)	NC score	0.018352 (rank : 69)
Query Neighborhood Hits	92	Target Neighborhood Hits	472	Shared Neighborhood Hits	8
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

RAE1_HUMAN
θ value	1.38821 (rank : 50)	NC score	0.019172 (rank : 65)
Query Neighborhood Hits	92	Target Neighborhood Hits	25	Shared Neighborhood Hits	4
SwissProt Accessions	P24386, O43732	Gene names	CHM, REP1, TCD
Domain Architecture
Description	Rab proteins geranylgeranyltransferase component A 1 (Rab escort protein 1) (REP-1) (Choroideraemia protein) (TCD protein).

GCDH_HUMAN
θ value	1.81305 (rank : 51)	NC score	0.014879 (rank : 74)
Query Neighborhood Hits	92	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	Q92947, O14719	Gene names	GCDH
Domain Architecture
Description	Glutaryl-CoA dehydrogenase, mitochondrial precursor (EC 1.3.99.7) (GCD).

K1802_HUMAN
θ value	1.81305 (rank : 52)	NC score	0.008304 (rank : 88)
Query Neighborhood Hits	92	Target Neighborhood Hits	1378	Shared Neighborhood Hits	12
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

MATR3_MOUSE
θ value	1.81305 (rank : 53)	NC score	0.040577 (rank : 41)
Query Neighborhood Hits	92	Target Neighborhood Hits	321	Shared Neighborhood Hits	19
SwissProt Accessions	Q8K310	Gene names	Matr3
Domain Architecture	No domain graphic available
Description	Matrin-3.

RPF53_MOUSE
θ value	1.81305 (rank : 54)	NC score	0.027495 (rank : 56)
Query Neighborhood Hits	92	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K202, Q62034, Q8BQG9	Gene names	Praf1, Paf53
Domain Architecture	No domain graphic available
Description	DNA-directed RNA polymerase I-associated factor 53 kDa subunit (EC 2.7.7.6) (RNA polymerase I-associated factor 1).

SAS10_HUMAN
θ value	1.81305 (rank : 55)	NC score	0.036138 (rank : 44)
Query Neighborhood Hits	92	Target Neighborhood Hits	102	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NQZ2, Q6FI82	Gene names	CRLZ1, SAS10
Domain Architecture	No domain graphic available
Description	Something about silencing protein 10 (Disrupter of silencing SAS10) (Charged amino acid-rich leucine zipper 1).

AP3B2_HUMAN
θ value	2.36792 (rank : 56)	NC score	0.029807 (rank : 53)
Query Neighborhood Hits	92	Target Neighborhood Hits	246	Shared Neighborhood Hits	22
SwissProt Accessions	Q13367, O14808	Gene names	AP3B2
Domain Architecture
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (AP-3 complex beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain) (Neuron-specific vesicle coat protein beta-NAP).

DHX30_MOUSE
θ value	2.36792 (rank : 57)	NC score	0.019146 (rank : 66)
Query Neighborhood Hits	92	Target Neighborhood Hits	45	Shared Neighborhood Hits	3
SwissProt Accessions	Q99PU8, Q3U4Z4, Q3UFA0, Q3UJS4, Q91WA7, Q99KN7	Gene names	Dhx30, Helg
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX30 (EC 3.6.1.-) (DEAH box protein 30).

EP15R_HUMAN
θ value	2.36792 (rank : 58)	NC score	0.017037 (rank : 70)
Query Neighborhood Hits	92	Target Neighborhood Hits	1083	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UBC2	Gene names	EPS15L1, EPS15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R).

ERCC5_HUMAN
θ value	2.36792 (rank : 59)	NC score	0.024600 (rank : 58)
Query Neighborhood Hits	92	Target Neighborhood Hits	162	Shared Neighborhood Hits	13
SwissProt Accessions	P28715, Q7Z2V3, Q8IZL6, Q8N1B7, Q9HD59	Gene names	ERCC5, XPG, XPGC
Domain Architecture
Description	DNA-repair protein complementing XP-G cells (Xeroderma pigmentosum group G-complementing protein) (DNA excision repair protein ERCC-5).

LAMB1_HUMAN
θ value	2.36792 (rank : 60)	NC score	0.008397 (rank : 87)
Query Neighborhood Hits	92	Target Neighborhood Hits	1018	Shared Neighborhood Hits	16
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

MATR3_HUMAN
θ value	2.36792 (rank : 61)	NC score	0.038333 (rank : 43)
Query Neighborhood Hits	92	Target Neighborhood Hits	325	Shared Neighborhood Hits	19
SwissProt Accessions	P43243, Q9UHW0, Q9UQ27	Gene names	MATR3, KIAA0723
Domain Architecture
Description	Matrin-3.

FA29A_HUMAN
θ value	3.0926 (rank : 62)	NC score	0.026149 (rank : 57)
Query Neighborhood Hits	92	Target Neighborhood Hits	88	Shared Neighborhood Hits	3
SwissProt Accessions	Q7Z4H7, Q6IQ10, Q6NZX5, Q8IZQ4, Q96FN0, Q9H950, Q9H998, Q9HCJ8, Q9NXT8	Gene names	FAM29A, KIAA1574
Domain Architecture	No domain graphic available
Description	Protein FAM29A.

GP158_MOUSE
θ value	3.0926 (rank : 63)	NC score	0.015715 (rank : 72)
Query Neighborhood Hits	92	Target Neighborhood Hits	82	Shared Neighborhood Hits	2
SwissProt Accessions	Q8C419, Q8CHB0	Gene names	Gpr158, Kiaa1136
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 158 precursor.

POT14_HUMAN
θ value	3.0926 (rank : 64)	NC score	0.029951 (rank : 52)
Query Neighborhood Hits	92	Target Neighborhood Hits	403	Shared Neighborhood Hits	19
SwissProt Accessions	Q6S5H5, Q6S5H6, Q6S8J2	Gene names	POTE14
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 14.

RP1L1_HUMAN
θ value	3.0926 (rank : 65)	NC score	0.034040 (rank : 46)
Query Neighborhood Hits	92	Target Neighborhood Hits	1072	Shared Neighborhood Hits	28
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

ANK2_HUMAN
θ value	4.03905 (rank : 66)	NC score	0.012796 (rank : 77)
Query Neighborhood Hits	92	Target Neighborhood Hits	1615	Shared Neighborhood Hits	29
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

SGOL2_MOUSE
θ value	4.03905 (rank : 67)	NC score	0.018590 (rank : 68)
Query Neighborhood Hits	92	Target Neighborhood Hits	112	Shared Neighborhood Hits	3
SwissProt Accessions	Q7TSY8, Q811I4, Q8C9C4, Q8CGJ4, Q9CS55	Gene names	Sgol2
Domain Architecture	No domain graphic available
Description	Shugoshin-like 2.

YTDC1_HUMAN
θ value	4.03905 (rank : 68)	NC score	0.034478 (rank : 45)
Query Neighborhood Hits	92	Target Neighborhood Hits	458	Shared Neighborhood Hits	23
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

AP3B2_MOUSE
θ value	5.27518 (rank : 69)	NC score	0.023238 (rank : 59)
Query Neighborhood Hits	92	Target Neighborhood Hits	246	Shared Neighborhood Hits	18
SwissProt Accessions	Q9JME5, Q6QR53, Q8R1E5	Gene names	Ap3b2
Domain Architecture	No domain graphic available
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain).

CSPG3_MOUSE
θ value	5.27518 (rank : 70)	NC score	0.003755 (rank : 91)
Query Neighborhood Hits	92	Target Neighborhood Hits	657	Shared Neighborhood Hits	9
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

DMP1_HUMAN
θ value	5.27518 (rank : 71)	NC score	0.060148 (rank : 25)
Query Neighborhood Hits	92	Target Neighborhood Hits	491	Shared Neighborhood Hits	31
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

EMR3_HUMAN
θ value	5.27518 (rank : 72)	NC score	0.003895 (rank : 90)
Query Neighborhood Hits	92	Target Neighborhood Hits	245	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BY15	Gene names	EMR3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 3 precursor (EGF-like module-containing mucin-like receptor EMR3).

ERC2_HUMAN
θ value	5.27518 (rank : 73)	NC score	0.009668 (rank : 83)
Query Neighborhood Hits	92	Target Neighborhood Hits	1156	Shared Neighborhood Hits	17
SwissProt Accessions	O15083, Q86TK4	Gene names	ERC2, KIAA0378
Domain Architecture	No domain graphic available
Description	ERC protein 2.

MYPC2_MOUSE
θ value	5.27518 (rank : 74)	NC score	0.004580 (rank : 89)
Query Neighborhood Hits	92	Target Neighborhood Hits	297	Shared Neighborhood Hits	3
SwissProt Accessions	Q5XKE0, Q8C109, Q8K2V0	Gene names	Mybpc2
Domain Architecture	No domain graphic available
Description	Myosin-binding protein C, fast-type (Fast MyBP-C) (C-protein, skeletal muscle fast isoform).

R51A1_MOUSE
θ value	5.27518 (rank : 75)	NC score	0.019737 (rank : 64)
Query Neighborhood Hits	92	Target Neighborhood Hits	164	Shared Neighborhood Hits	8
SwissProt Accessions	Q8C551, O55219, Q8BP36, Q99L94, Q9D0J0	Gene names	Rad51ap1
Domain Architecture	No domain graphic available
Description	RAD51-associated protein 1 (RAD51-interacting protein) (RAB22).

SMBT1_HUMAN
θ value	5.27518 (rank : 76)	NC score	0.010652 (rank : 81)
Query Neighborhood Hits	92	Target Neighborhood Hits	53	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UHJ3, Q96C73, Q9Y4Q9	Gene names	SFMBT1, RU1
Domain Architecture	No domain graphic available
Description	Scm-like with four MBT domains protein 1 (Renal ubiquitous protein 1).

TFR1_HUMAN
θ value	5.27518 (rank : 77)	NC score	0.023017 (rank : 60)
Query Neighborhood Hits	92	Target Neighborhood Hits	22	Shared Neighborhood Hits	5
SwissProt Accessions	P02786, Q59G55, Q9UCN0, Q9UCU5, Q9UDF9, Q9UK21	Gene names	TFRC
Domain Architecture
Description	Transferrin receptor protein 1 (TfR1) (TR) (TfR) (Trfr) (CD71 antigen) (T9) (p90).

ENL_HUMAN
θ value	6.88961 (rank : 78)	NC score	0.032260 (rank : 50)
Query Neighborhood Hits	92	Target Neighborhood Hits	305	Shared Neighborhood Hits	14
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

HOOK1_HUMAN
θ value	6.88961 (rank : 79)	NC score	0.009306 (rank : 85)
Query Neighborhood Hits	92	Target Neighborhood Hits	942	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UJC3, O60561, Q5TG44	Gene names	HOOK1
Domain Architecture
Description	Hook homolog 1 (h-hook1) (hHK1).

HOOK1_MOUSE
θ value	6.88961 (rank : 80)	NC score	0.009460 (rank : 84)
Query Neighborhood Hits	92	Target Neighborhood Hits	910	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BIL5, Q8BIZ2, Q8K0P1, Q8K454, Q9CTN6	Gene names	Hook1
Domain Architecture
Description	Hook homolog 1.

LRFN5_MOUSE
θ value	6.88961 (rank : 81)	NC score	0.001167 (rank : 92)
Query Neighborhood Hits	92	Target Neighborhood Hits	472	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BXA0, Q8BJH4, Q8BZL0	Gene names	Lrfn5
Domain Architecture
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 5 precursor.

MYT1_HUMAN
θ value	6.88961 (rank : 82)	NC score	0.029312 (rank : 54)
Query Neighborhood Hits	92	Target Neighborhood Hits	475	Shared Neighborhood Hits	23
SwissProt Accessions	Q01538, O94922, Q9UPV2	Gene names	MYT1, KIAA0835, KIAA1050, MTF1, MYTI, PLPB1
Domain Architecture
Description	Myelin transcription factor 1 (MyT1) (MyTI) (Proteolipid protein- binding protein) (PLPB1).

UBF1_HUMAN
θ value	6.88961 (rank : 83)	NC score	0.027614 (rank : 55)
Query Neighborhood Hits	92	Target Neighborhood Hits	415	Shared Neighborhood Hits	21
SwissProt Accessions	P17480	Gene names	UBTF, UBF, UBF1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1) (Autoantigen NOR-90).

YETS2_HUMAN
θ value	6.88961 (rank : 84)	NC score	0.015675 (rank : 73)
Query Neighborhood Hits	92	Target Neighborhood Hits	212	Shared Neighborhood Hits	13
SwissProt Accessions	Q9ULM3, Q641P6, Q9NW96	Gene names	YEATS2, KIAA1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

CHD1_HUMAN
θ value	8.99809 (rank : 85)	NC score	0.014309 (rank : 75)
Query Neighborhood Hits	92	Target Neighborhood Hits	337	Shared Neighborhood Hits	17
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

ERC2_MOUSE
θ value	8.99809 (rank : 86)	NC score	0.008503 (rank : 86)
Query Neighborhood Hits	92	Target Neighborhood Hits	1166	Shared Neighborhood Hits	16
SwissProt Accessions	Q6PH08, Q80U20, Q8CCP1	Gene names	Erc2, Cast1, D14Ertd171e, Kiaa0378
Domain Architecture	No domain graphic available
Description	ERC protein 2 (CAZ-associated structural protein 1) (CAST1).

PPHLN_MOUSE
θ value	8.99809 (rank : 87)	NC score	0.013525 (rank : 76)
Query Neighborhood Hits	92	Target Neighborhood Hits	41	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K2H1, Q8BUZ6	Gene names	Pphln1
Domain Architecture	No domain graphic available
Description	Periphilin-1.

PSL2_MOUSE
θ value	8.99809 (rank : 88)	NC score	0.056800 (rank : 28)
Query Neighborhood Hits	92	Target Neighborhood Hits	19	Shared Neighborhood Hits	7
SwissProt Accessions	Q9JJF9, Q8R354	Gene names	Sppl2a, Psl2
Domain Architecture
Description	Signal peptide peptidase-like 2A (EC 3.4.23.-) (SPP-like 2A protein) (Protein SPPL2a) (Intramembrane protease 3) (IMP3) (Presenilin-like protein 2).

RPGR1_HUMAN
θ value	8.99809 (rank : 89)	NC score	0.010023 (rank : 82)
Query Neighborhood Hits	92	Target Neighborhood Hits	578	Shared Neighborhood Hits	14
SwissProt Accessions	Q96KN7, Q7Z2W6, Q8IXV5, Q96QA8, Q9HB94, Q9HB95, Q9HBK6, Q9NR40	Gene names	RPGRIP1
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

SPRL1_MOUSE
θ value	8.99809 (rank : 90)	NC score	0.041044 (rank : 40)
Query Neighborhood Hits	92	Target Neighborhood Hits	403	Shared Neighborhood Hits	25
SwissProt Accessions	P70663, P97810, Q99L82	Gene names	Sparcl1, Ecm2, Sc1
Domain Architecture
Description	SPARC-like protein 1 precursor (Matrix glycoprotein Sc1) (Extracellular matrix protein 2).

TARA_HUMAN
θ value	8.99809 (rank : 91)	NC score	0.011328 (rank : 80)
Query Neighborhood Hits	92	Target Neighborhood Hits	1626	Shared Neighborhood Hits	26
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TGON2_MOUSE
θ value	8.99809 (rank : 92)	NC score	0.021824 (rank : 62)
Query Neighborhood Hits	92	Target Neighborhood Hits	277	Shared Neighborhood Hits	18
SwissProt Accessions	Q62314	Gene names	Tgoln2, Ttgn2
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 2 precursor (TGN38B).

Hits sorted by NC score

EDEM3_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	92	Target Neighborhood Hits	92	Shared Neighborhood Hits	92
SwissProt Accessions	Q9BZQ6, Q5TEZ0, Q9HCW1, Q9UFV7	Gene names	EDEM3, C1orf22
Domain Architecture
Description	ER degradation-enhancing alpha-mannosidase-like 3.

EDEM1_HUMAN
NC score	0.929976 (rank : 2)	θ value	1.43912e-106 (rank : 2)
Query Neighborhood Hits	92	Target Neighborhood Hits	24	Shared Neighborhood Hits	11
SwissProt Accessions	Q92611	Gene names	EDEM1, EDEM, KIAA0212
Domain Architecture
Description	ER degradation-enhancing alpha-mannosidase-like 1.

EDEM1_MOUSE
NC score	0.928802 (rank : 3)	θ value	1.43912e-106 (rank : 3)
Query Neighborhood Hits	92	Target Neighborhood Hits	23	Shared Neighborhood Hits	11
SwissProt Accessions	Q925U4	Gene names	Edem1, Edem
Domain Architecture
Description	ER degradation-enhancing alpha-mannosidase-like 1.

EDEM2_HUMAN
NC score	0.927857 (rank : 4)	θ value	2.47191e-82 (rank : 4)
Query Neighborhood Hits	92	Target Neighborhood Hits	16	Shared Neighborhood Hits	10
SwissProt Accessions	Q9BV94, Q6IA89, Q6UWZ4, Q9H4U0, Q9H886, Q9NTL9, Q9NVE6	Gene names	EDEM2, C20orf31, C20orf49
Domain Architecture
Description	ER degradation-enhancing alpha-mannosidase-like 2 precursor.

MA1B1_HUMAN
NC score	0.850558 (rank : 5)	θ value	2.25659e-51 (rank : 5)
Query Neighborhood Hits	92	Target Neighborhood Hits	125	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UKM7, Q5VSG3, Q9BRS9, Q9Y5K7	Gene names	MAN1B1
Domain Architecture
Description	Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase (EC 3.2.1.113) (ER alpha-1,2-mannosidase) (Mannosidase alpha class 1B member 1) (Man9GlcNAc2-specific-processing alpha-mannosidase).

MA1A1_HUMAN
NC score	0.832578 (rank : 6)	θ value	3.98324e-48 (rank : 6)
Query Neighborhood Hits	92	Target Neighborhood Hits	26	Shared Neighborhood Hits	10
SwissProt Accessions	P33908, Q9NU44, Q9UJI3	Gene names	MAN1A1
Domain Architecture
Description	Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA (EC 3.2.1.113) (Processing alpha-1,2-mannosidase IA) (Alpha-1,2-mannosidase IA) (Mannosidase alpha class 1A member 1) (Man(9)-alpha-mannosidase) (Man9-mannosidase).

MA1A1_MOUSE
NC score	0.831835 (rank : 7)	θ value	7.51208e-47 (rank : 7)
Query Neighborhood Hits	92	Target Neighborhood Hits	32	Shared Neighborhood Hits	10
SwissProt Accessions	P45700	Gene names	Man1a1, Man1a
Domain Architecture
Description	Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA (EC 3.2.1.113) (Processing alpha-1,2-mannosidase IA) (Alpha-1,2-mannosidase IA) (Mannosidase alpha class 1A member 1) (Man(9)-alpha-mannosidase) (Man9-mannosidase).

MA1C1_HUMAN
NC score	0.829305 (rank : 8)	θ value	3.86705e-35 (rank : 10)
Query Neighborhood Hits	92	Target Neighborhood Hits	21	Shared Neighborhood Hits	11
SwissProt Accessions	Q9NR34, Q9Y545	Gene names	MAN1C1, MAN1A3, MAN1C
Domain Architecture
Description	Mannosyl-oligosaccharide 1,2-alpha-mannosidase IC (EC 3.2.1.113) (Processing alpha-1,2-mannosidase IC) (Alpha-1,2-mannosidase IC) (Mannosidase alpha class 1C member 1) (HMIC).

MA1A2_HUMAN
NC score	0.824776 (rank : 9)	θ value	2.86122e-38 (rank : 8)
Query Neighborhood Hits	92	Target Neighborhood Hits	31	Shared Neighborhood Hits	12
SwissProt Accessions	O60476, Q9H510	Gene names	MAN1A2, MAN1B
Domain Architecture
Description	Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB (EC 3.2.1.113) (Processing alpha-1,2-mannosidase IB) (Alpha-1,2-mannosidase IB) (Mannosidase alpha class 1A member 2).

MA1A2_MOUSE
NC score	0.821882 (rank : 10)	θ value	9.20422e-37 (rank : 9)
Query Neighborhood Hits	92	Target Neighborhood Hits	31	Shared Neighborhood Hits	10
SwissProt Accessions	P39098, Q5SUY6, Q5SUY7, Q60599, Q9CUY9	Gene names	Man1a2, Man1b
Domain Architecture
Description	Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB (EC 3.2.1.113) (Processing alpha-1,2-mannosidase IB) (Alpha-1,2-mannosidase IB) (Mannosidase alpha class 1A member 2).

PAP21_MOUSE
NC score	0.200492 (rank : 11)	θ value	2.88788e-06 (rank : 12)
Query Neighborhood Hits	92	Target Neighborhood Hits	11	Shared Neighborhood Hits	11
SwissProt Accessions	Q9D9N8	Gene names	Pap21
Domain Architecture	No domain graphic available
Description	Protease-associated domain-containing protein of 21 kDa precursor.

PAP21_HUMAN
NC score	0.200445 (rank : 12)	θ value	2.88788e-06 (rank : 11)
Query Neighborhood Hits	92	Target Neighborhood Hits	11	Shared Neighborhood Hits	11
SwissProt Accessions	Q9BSG0	Gene names	PAP21, C2orf7
Domain Architecture	No domain graphic available
Description	Protease-associated domain-containing protein of 21 kDa precursor (hPAP21).

RNF13_MOUSE
NC score	0.113956 (rank : 13)	θ value	0.00102713 (rank : 13)
Query Neighborhood Hits	92	Target Neighborhood Hits	164	Shared Neighborhood Hits	12
SwissProt Accessions	O54965, O54966	Gene names	Rnf13, Rzf
Domain Architecture
Description	RING finger protein 13.

RN167_HUMAN
NC score	0.108891 (rank : 14)	θ value	0.00228821 (rank : 15)
Query Neighborhood Hits	92	Target Neighborhood Hits	157	Shared Neighborhood Hits	9
SwissProt Accessions	Q9H6Y7, Q6XYE0, Q8NDC1, Q9Y3V1	Gene names	RNF167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

RNF13_HUMAN
NC score	0.108468 (rank : 15)	θ value	0.00665767 (rank : 17)
Query Neighborhood Hits	92	Target Neighborhood Hits	147	Shared Neighborhood Hits	10
SwissProt Accessions	O43567	Gene names	RNF13, RZF
Domain Architecture
Description	RING finger protein 13.

RN167_MOUSE
NC score	0.106663 (rank : 16)	θ value	0.0148317 (rank : 19)
Query Neighborhood Hits	92	Target Neighborhood Hits	157	Shared Neighborhood Hits	11
SwissProt Accessions	Q91XF4, Q3U4S5	Gene names	Rnf167
Domain Architecture	No domain graphic available
Description	RING finger protein 167 precursor.

RN133_HUMAN
NC score	0.086332 (rank : 17)	θ value	0.47712 (rank : 38)
Query Neighborhood Hits	92	Target Neighborhood Hits	108	Shared Neighborhood Hits	12
SwissProt Accessions	Q8WVZ7, Q8N7G7	Gene names	RNF133
Domain Architecture	No domain graphic available
Description	RING finger protein 133.

DMP1_MOUSE
NC score	0.084328 (rank : 18)	θ value	0.00869519 (rank : 18)
Query Neighborhood Hits	92	Target Neighborhood Hits	498	Shared Neighborhood Hits	35
SwissProt Accessions	O55188	Gene names	Dmp1, Dmp
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1) (AG1).

PSL1_MOUSE
NC score	0.078480 (rank : 19)	θ value	0.0252991 (rank : 20)
Query Neighborhood Hits	92	Target Neighborhood Hits	32	Shared Neighborhood Hits	10
SwissProt Accessions	Q3TD49, Q3TLQ8, Q3UG60, Q80VZ6	Gene names	Sppl2b
Domain Architecture	No domain graphic available
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b).

GOLI_HUMAN
NC score	0.073448 (rank : 20)	θ value	0.813845 (rank : 43)
Query Neighborhood Hits	92	Target Neighborhood Hits	137	Shared Neighborhood Hits	15
SwissProt Accessions	Q86XS8, Q641P9, Q6P177, Q7L2U2, Q9P0J9	Gene names	RNF130
Domain Architecture	No domain graphic available
Description	Goliath homolog precursor (RING finger protein 130).

GOLI_MOUSE
NC score	0.073419 (rank : 21)	θ value	0.813845 (rank : 44)
Query Neighborhood Hits	92	Target Neighborhood Hits	134	Shared Neighborhood Hits	15
SwissProt Accessions	Q8VEM1, Q80VL7, Q9QZQ6	Gene names	Rnf130, G1rp
Domain Architecture	No domain graphic available
Description	Goliath homolog precursor (RING finger protein 130) (G1-related zinc finger protein).

LEO1_MOUSE
NC score	0.071940 (rank : 22)	θ value	0.00298849 (rank : 16)
Query Neighborhood Hits	92	Target Neighborhood Hits	946	Shared Neighborhood Hits	39
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

PSL2_HUMAN
NC score	0.071494 (rank : 23)	θ value	0.0961366 (rank : 26)
Query Neighborhood Hits	92	Target Neighborhood Hits	19	Shared Neighborhood Hits	7
SwissProt Accessions	Q8TCT8, Q8TAW1, Q96SZ8	Gene names	SPPL2A, PSL2
Domain Architecture
Description	Signal peptide peptidase-like 2A (EC 3.4.23.-) (Protein SPP-like 2A) (Protein SPPL2a) (Intramembrane protease 3) (IMP3) (Presenilin-like protein 2).

LEO1_HUMAN
NC score	0.065189 (rank : 24)	θ value	0.365318 (rank : 35)
Query Neighborhood Hits	92	Target Neighborhood Hits	958	Shared Neighborhood Hits	43
SwissProt Accessions	Q8WVC0, Q96N99	Gene names	LEO1, RDL
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1 (Replicative senescence down- regulated leo1-like protein).

DMP1_HUMAN
NC score	0.060148 (rank : 25)	θ value	5.27518 (rank : 71)
Query Neighborhood Hits	92	Target Neighborhood Hits	491	Shared Neighborhood Hits	31
SwissProt Accessions	Q13316, O43265	Gene names	DMP1
Domain Architecture
Description	Dentin matrix acidic phosphoprotein 1 precursor (Dentin matrix protein 1) (DMP-1).

ABTAP_MOUSE
NC score	0.057635 (rank : 26)	θ value	0.0563607 (rank : 23)
Query Neighborhood Hits	92	Target Neighborhood Hits	381	Shared Neighborhood Hits	23
SwissProt Accessions	Q3V1V3	Gene names	Abtap
Domain Architecture	No domain graphic available
Description	ABT1-associated protein.

PSL1_HUMAN
NC score	0.057333 (rank : 27)	θ value	0.47712 (rank : 37)
Query Neighborhood Hits	92	Target Neighborhood Hits	650	Shared Neighborhood Hits	13
SwissProt Accessions	Q8TCT7, O60365, Q567S3, Q8IUH9, Q9BUY6, Q9H3M4, Q9NPN2, Q9P1Z6	Gene names	SPPL2B, KIAA1532, PSL1
Domain Architecture
Description	Signal peptide peptidase-like 2B (EC 3.4.23.-) (Protein SPP-like 2B) (Protein SPPL2b) (Intramembrane protease 4) (IMP4) (Presenilin-like protein 1).

PSL2_MOUSE
NC score	0.056800 (rank : 28)	θ value	8.99809 (rank : 88)
Query Neighborhood Hits	92	Target Neighborhood Hits	19	Shared Neighborhood Hits	7
SwissProt Accessions	Q9JJF9, Q8R354	Gene names	Sppl2a, Psl2
Domain Architecture
Description	Signal peptide peptidase-like 2A (EC 3.4.23.-) (SPP-like 2A protein) (Protein SPPL2a) (Intramembrane protease 3) (IMP3) (Presenilin-like protein 2).

IWS1_HUMAN
NC score	0.055312 (rank : 29)	θ value	0.0330416 (rank : 22)
Query Neighborhood Hits	92	Target Neighborhood Hits	1241	Shared Neighborhood Hits	40
SwissProt Accessions	Q96ST2, Q6P157, Q8N3E8, Q96MI7, Q9NV97, Q9NWH8	Gene names	IWS1, IWS1L
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

SPRL1_HUMAN
NC score	0.054323 (rank : 30)	θ value	0.163984 (rank : 28)
Query Neighborhood Hits	92	Target Neighborhood Hits	231	Shared Neighborhood Hits	22
SwissProt Accessions	Q14515, Q14800	Gene names	SPARCL1
Domain Architecture
Description	SPARC-like protein 1 precursor (High endothelial venule protein) (Hevin) (MAST 9).

CENPB_MOUSE
NC score	0.054028 (rank : 31)	θ value	0.365318 (rank : 33)
Query Neighborhood Hits	92	Target Neighborhood Hits	163	Shared Neighborhood Hits	16
SwissProt Accessions	P27790	Gene names	Cenpb, Cenp-b
Domain Architecture
Description	Major centromere autoantigen B (Centromere protein B) (CENP-B).

RP1L1_MOUSE
NC score	0.050785 (rank : 32)	θ value	0.21417 (rank : 29)
Query Neighborhood Hits	92	Target Neighborhood Hits	170	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CGM2, Q8K0I4	Gene names	Rp1l1, Rp1hl1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein (Retinitis pigmentosa 1-like protein 1).

CF051_HUMAN
NC score	0.050736 (rank : 33)	θ value	1.06291 (rank : 45)
Query Neighborhood Hits	92	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q969F1	Gene names	C6orf51
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf51.

CB010_HUMAN
NC score	0.049939 (rank : 34)	θ value	0.279714 (rank : 31)
Query Neighborhood Hits	92	Target Neighborhood Hits	130	Shared Neighborhood Hits	5
SwissProt Accessions	Q7Z570, Q6ZN26	Gene names	C2orf10
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C2orf10.

MIER1_MOUSE
NC score	0.048209 (rank : 35)	θ value	0.47712 (rank : 36)
Query Neighborhood Hits	92	Target Neighborhood Hits	84	Shared Neighborhood Hits	7
SwissProt Accessions	Q5UAK0, Q5UAK1, Q5UAK2, Q5UAK3, Q6ZPL6, Q9D402	Gene names	Mier1, Kiaa1610
Domain Architecture	No domain graphic available
Description	Mesoderm induction early response protein 1 (Mi-er1).

AKA12_HUMAN
NC score	0.047679 (rank : 36)	θ value	0.365318 (rank : 32)
Query Neighborhood Hits	92	Target Neighborhood Hits	825	Shared Neighborhood Hits	30
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

DSPP_HUMAN
NC score	0.046441 (rank : 37)	θ value	0.62314 (rank : 40)
Query Neighborhood Hits	92	Target Neighborhood Hits	645	Shared Neighborhood Hits	28
SwissProt Accessions	Q9NZW4, O95815	Gene names	DSPP
Domain Architecture	No domain graphic available
Description	Dentin sialophosphoprotein precursor [Contains: Dentin phosphoprotein (Dentin phosphophoryn) (DPP); Dentin sialoprotein (DSP)].

MIER1_HUMAN
NC score	0.044571 (rank : 38)	θ value	1.38821 (rank : 48)
Query Neighborhood Hits	92	Target Neighborhood Hits	75	Shared Neighborhood Hits	8
SwissProt Accessions	Q8N108, Q5T104, Q6AHY8, Q86TB4, Q8N156, Q8N161, Q8NC37, Q8NES4, Q8NES5, Q8NES6, Q8WWG2, Q9HCG2	Gene names	MIER1, KIAA1610
Domain Architecture	No domain graphic available
Description	Mesoderm induction early response protein 1 (Mi-er1) (hmi-er1) (Early response 1) (Er1).

SSH2_HUMAN
NC score	0.042511 (rank : 39)	θ value	0.00102713 (rank : 14)
Query Neighborhood Hits	92	Target Neighborhood Hits	140	Shared Neighborhood Hits	3
SwissProt Accessions	Q76I76, Q8TDB5, Q8WYL1, Q8WYL2, Q96F40, Q96H36, Q9C0D8	Gene names	SSH2, KIAA1725, SSH2L
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 2 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-2L) (hSSH-2L).

SPRL1_MOUSE
NC score	0.041044 (rank : 40)	θ value	8.99809 (rank : 90)
Query Neighborhood Hits	92	Target Neighborhood Hits	403	Shared Neighborhood Hits	25
SwissProt Accessions	P70663, P97810, Q99L82	Gene names	Sparcl1, Ecm2, Sc1
Domain Architecture
Description	SPARC-like protein 1 precursor (Matrix glycoprotein Sc1) (Extracellular matrix protein 2).

MATR3_MOUSE
NC score	0.040577 (rank : 41)	θ value	1.81305 (rank : 53)
Query Neighborhood Hits	92	Target Neighborhood Hits	321	Shared Neighborhood Hits	19
SwissProt Accessions	Q8K310	Gene names	Matr3
Domain Architecture	No domain graphic available
Description	Matrin-3.

BPTF_HUMAN
NC score	0.039164 (rank : 42)	θ value	0.125558 (rank : 27)
Query Neighborhood Hits	92	Target Neighborhood Hits	786	Shared Neighborhood Hits	32
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

MATR3_HUMAN
NC score	0.038333 (rank : 43)	θ value	2.36792 (rank : 61)
Query Neighborhood Hits	92	Target Neighborhood Hits	325	Shared Neighborhood Hits	19
SwissProt Accessions	P43243, Q9UHW0, Q9UQ27	Gene names	MATR3, KIAA0723
Domain Architecture
Description	Matrin-3.

SAS10_HUMAN
NC score	0.036138 (rank : 44)	θ value	1.81305 (rank : 55)
Query Neighborhood Hits	92	Target Neighborhood Hits	102	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NQZ2, Q6FI82	Gene names	CRLZ1, SAS10
Domain Architecture	No domain graphic available
Description	Something about silencing protein 10 (Disrupter of silencing SAS10) (Charged amino acid-rich leucine zipper 1).

YTDC1_HUMAN
NC score	0.034478 (rank : 45)	θ value	4.03905 (rank : 68)
Query Neighborhood Hits	92	Target Neighborhood Hits	458	Shared Neighborhood Hits	23
SwissProt Accessions	Q96MU7, Q7Z622, Q8TF35	Gene names	YTHDC1, KIAA1966, YT521
Domain Architecture
Description	YTH domain-containing protein 1 (Putative splicing factor YT521).

RP1L1_HUMAN
NC score	0.034040 (rank : 46)	θ value	3.0926 (rank : 65)
Query Neighborhood Hits	92	Target Neighborhood Hits	1072	Shared Neighborhood Hits	28
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

ANR21_HUMAN
NC score	0.033948 (rank : 47)	θ value	0.0330416 (rank : 21)
Query Neighborhood Hits	92	Target Neighborhood Hits	864	Shared Neighborhood Hits	27
SwissProt Accessions	Q86YR6	Gene names	ANKRD21, POTE
Domain Architecture
Description	Ankyrin repeat domain-containing protein 21 (Protein POTE) (Prostate, ovary, testis-expressed protein).

POT15_HUMAN
NC score	0.033451 (rank : 48)	θ value	0.0563607 (rank : 24)
Query Neighborhood Hits	92	Target Neighborhood Hits	893	Shared Neighborhood Hits	29
SwissProt Accessions	Q6S5H4, Q6NXN7, Q6S5H7	Gene names	POTE15
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 15.

TFR1_MOUSE
NC score	0.032683 (rank : 49)	θ value	0.21417 (rank : 30)
Query Neighborhood Hits	92	Target Neighborhood Hits	24	Shared Neighborhood Hits	5
SwissProt Accessions	Q62351, Q61560	Gene names	Tfrc, Trfr
Domain Architecture
Description	Transferrin receptor protein 1 (TfR1) (TR) (TfR) (Trfr) (CD71 antigen).

ENL_HUMAN
NC score	0.032260 (rank : 50)	θ value	6.88961 (rank : 78)
Query Neighborhood Hits	92	Target Neighborhood Hits	305	Shared Neighborhood Hits	14
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

MYT1_MOUSE
NC score	0.032008 (rank : 51)	θ value	0.62314 (rank : 42)
Query Neighborhood Hits	92	Target Neighborhood Hits	385	Shared Neighborhood Hits	16
SwissProt Accessions	Q8CFC2, O08995, Q8CFH1	Gene names	Myt1, Kiaa0835, Nzf2
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1 (MyT1) (Neural zinc finger factor 2) (NZF-2).

POT14_HUMAN
NC score	0.029951 (rank : 52)	θ value	3.0926 (rank : 64)
Query Neighborhood Hits	92	Target Neighborhood Hits	403	Shared Neighborhood Hits	19
SwissProt Accessions	Q6S5H5, Q6S5H6, Q6S8J2	Gene names	POTE14
Domain Architecture	No domain graphic available
Description	Prostate, ovary, testis-expressed protein on chromosome 14.

AP3B2_HUMAN
NC score	0.029807 (rank : 53)	θ value	2.36792 (rank : 56)
Query Neighborhood Hits	92	Target Neighborhood Hits	246	Shared Neighborhood Hits	22
SwissProt Accessions	Q13367, O14808	Gene names	AP3B2
Domain Architecture
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (AP-3 complex beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain) (Neuron-specific vesicle coat protein beta-NAP).

MYT1_HUMAN
NC score	0.029312 (rank : 54)	θ value	6.88961 (rank : 82)
Query Neighborhood Hits	92	Target Neighborhood Hits	475	Shared Neighborhood Hits	23
SwissProt Accessions	Q01538, O94922, Q9UPV2	Gene names	MYT1, KIAA0835, KIAA1050, MTF1, MYTI, PLPB1
Domain Architecture
Description	Myelin transcription factor 1 (MyT1) (MyTI) (Proteolipid protein- binding protein) (PLPB1).

UBF1_HUMAN
NC score	0.027614 (rank : 55)	θ value	6.88961 (rank : 83)
Query Neighborhood Hits	92	Target Neighborhood Hits	415	Shared Neighborhood Hits	21
SwissProt Accessions	P17480	Gene names	UBTF, UBF, UBF1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1) (Autoantigen NOR-90).

RPF53_MOUSE
NC score	0.027495 (rank : 56)	θ value	1.81305 (rank : 54)
Query Neighborhood Hits	92	Target Neighborhood Hits	7	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K202, Q62034, Q8BQG9	Gene names	Praf1, Paf53
Domain Architecture	No domain graphic available
Description	DNA-directed RNA polymerase I-associated factor 53 kDa subunit (EC 2.7.7.6) (RNA polymerase I-associated factor 1).

FA29A_HUMAN
NC score	0.026149 (rank : 57)	θ value	3.0926 (rank : 62)
Query Neighborhood Hits	92	Target Neighborhood Hits	88	Shared Neighborhood Hits	3
SwissProt Accessions	Q7Z4H7, Q6IQ10, Q6NZX5, Q8IZQ4, Q96FN0, Q9H950, Q9H998, Q9HCJ8, Q9NXT8	Gene names	FAM29A, KIAA1574
Domain Architecture	No domain graphic available
Description	Protein FAM29A.

ERCC5_HUMAN
NC score	0.024600 (rank : 58)	θ value	2.36792 (rank : 59)
Query Neighborhood Hits	92	Target Neighborhood Hits	162	Shared Neighborhood Hits	13
SwissProt Accessions	P28715, Q7Z2V3, Q8IZL6, Q8N1B7, Q9HD59	Gene names	ERCC5, XPG, XPGC
Domain Architecture
Description	DNA-repair protein complementing XP-G cells (Xeroderma pigmentosum group G-complementing protein) (DNA excision repair protein ERCC-5).

AP3B2_MOUSE
NC score	0.023238 (rank : 59)	θ value	5.27518 (rank : 69)
Query Neighborhood Hits	92	Target Neighborhood Hits	246	Shared Neighborhood Hits	18
SwissProt Accessions	Q9JME5, Q6QR53, Q8R1E5	Gene names	Ap3b2
Domain Architecture	No domain graphic available
Description	AP-3 complex subunit beta-2 (Adapter-related protein complex 3 beta-2 subunit) (Beta3B-adaptin) (Adaptor protein complex AP-3 beta-2 subunit) (Clathrin assembly protein complex 3 beta-2 large chain).

TFR1_HUMAN
NC score	0.023017 (rank : 60)	θ value	5.27518 (rank : 77)
Query Neighborhood Hits	92	Target Neighborhood Hits	22	Shared Neighborhood Hits	5
SwissProt Accessions	P02786, Q59G55, Q9UCN0, Q9UCU5, Q9UDF9, Q9UK21	Gene names	TFRC
Domain Architecture
Description	Transferrin receptor protein 1 (TfR1) (TR) (TfR) (Trfr) (CD71 antigen) (T9) (p90).

DHX30_HUMAN
NC score	0.022605 (rank : 61)	θ value	0.365318 (rank : 34)
Query Neighborhood Hits	92	Target Neighborhood Hits	43	Shared Neighborhood Hits	3
SwissProt Accessions	Q7L2E3, O94965, Q7Z753, Q96CH4	Gene names	DHX30, KIAA0890
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX30 (EC 3.6.1.-) (DEAH box protein 30).

TGON2_MOUSE
NC score	0.021824 (rank : 62)	θ value	8.99809 (rank : 92)
Query Neighborhood Hits	92	Target Neighborhood Hits	277	Shared Neighborhood Hits	18
SwissProt Accessions	Q62314	Gene names	Tgoln2, Ttgn2
Domain Architecture	No domain graphic available
Description	Trans-Golgi network integral membrane protein 2 precursor (TGN38B).

ZHX2_HUMAN
NC score	0.021731 (rank : 63)	θ value	0.47712 (rank : 39)
Query Neighborhood Hits	92	Target Neighborhood Hits	347	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y6X8	Gene names	ZHX2, AFR1, KIAA0854, RAF
Domain Architecture
Description	Zinc fingers and homeoboxes protein 2 (Zinc finger and homeodomain protein 2) (Alpha-fetoprotein regulator 1) (AFP regulator 1) (Regulator of AFP).

R51A1_MOUSE
NC score	0.019737 (rank : 64)	θ value	5.27518 (rank : 75)
Query Neighborhood Hits	92	Target Neighborhood Hits	164	Shared Neighborhood Hits	8
SwissProt Accessions	Q8C551, O55219, Q8BP36, Q99L94, Q9D0J0	Gene names	Rad51ap1
Domain Architecture	No domain graphic available
Description	RAD51-associated protein 1 (RAD51-interacting protein) (RAB22).

RAE1_HUMAN
NC score	0.019172 (rank : 65)	θ value	1.38821 (rank : 50)
Query Neighborhood Hits	92	Target Neighborhood Hits	25	Shared Neighborhood Hits	4
SwissProt Accessions	P24386, O43732	Gene names	CHM, REP1, TCD
Domain Architecture
Description	Rab proteins geranylgeranyltransferase component A 1 (Rab escort protein 1) (REP-1) (Choroideraemia protein) (TCD protein).

DHX30_MOUSE
NC score	0.019146 (rank : 66)	θ value	2.36792 (rank : 57)
Query Neighborhood Hits	92	Target Neighborhood Hits	45	Shared Neighborhood Hits	3
SwissProt Accessions	Q99PU8, Q3U4Z4, Q3UFA0, Q3UJS4, Q91WA7, Q99KN7	Gene names	Dhx30, Helg
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX30 (EC 3.6.1.-) (DEAH box protein 30).

EP15R_MOUSE
NC score	0.018957 (rank : 67)	θ value	1.06291 (rank : 47)
Query Neighborhood Hits	92	Target Neighborhood Hits	1135	Shared Neighborhood Hits	24
SwissProt Accessions	Q60902, Q8CB60, Q8CB70, Q91WH8	Gene names	Eps15l1, Eps15-rs, Eps15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R) (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs).

SGOL2_MOUSE
NC score	0.018590 (rank : 68)	θ value	4.03905 (rank : 67)
Query Neighborhood Hits	92	Target Neighborhood Hits	112	Shared Neighborhood Hits	3
SwissProt Accessions	Q7TSY8, Q811I4, Q8C9C4, Q8CGJ4, Q9CS55	Gene names	Sgol2
Domain Architecture	No domain graphic available
Description	Shugoshin-like 2.

NSD1_MOUSE
NC score	0.018352 (rank : 69)	θ value	1.38821 (rank : 49)
Query Neighborhood Hits	92	Target Neighborhood Hits	472	Shared Neighborhood Hits	8
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

EP15R_HUMAN
NC score	0.017037 (rank : 70)	θ value	2.36792 (rank : 58)
Query Neighborhood Hits	92	Target Neighborhood Hits	1083	Shared Neighborhood Hits	24
SwissProt Accessions	Q9UBC2	Gene names	EPS15L1, EPS15R
Domain Architecture
Description	Epidermal growth factor receptor substrate 15-like 1 (Eps15-related protein) (Eps15R).

CHD2_HUMAN
NC score	0.016724 (rank : 71)	θ value	1.06291 (rank : 46)
Query Neighborhood Hits	92	Target Neighborhood Hits	360	Shared Neighborhood Hits	16
SwissProt Accessions	O14647	Gene names	CHD2
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 2 (EC 3.6.1.-) (ATP- dependent helicase CHD2) (CHD-2).

GP158_MOUSE
NC score	0.015715 (rank : 72)	θ value	3.0926 (rank : 63)
Query Neighborhood Hits	92	Target Neighborhood Hits	82	Shared Neighborhood Hits	2
SwissProt Accessions	Q8C419, Q8CHB0	Gene names	Gpr158, Kiaa1136
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 158 precursor.

YETS2_HUMAN
NC score	0.015675 (rank : 73)	θ value	6.88961 (rank : 84)
Query Neighborhood Hits	92	Target Neighborhood Hits	212	Shared Neighborhood Hits	13
SwissProt Accessions	Q9ULM3, Q641P6, Q9NW96	Gene names	YEATS2, KIAA1197
Domain Architecture	No domain graphic available
Description	YEATS domain-containing protein 2.

GCDH_HUMAN
NC score	0.014879 (rank : 74)	θ value	1.81305 (rank : 51)
Query Neighborhood Hits	92	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	Q92947, O14719	Gene names	GCDH
Domain Architecture
Description	Glutaryl-CoA dehydrogenase, mitochondrial precursor (EC 1.3.99.7) (GCD).

CHD1_HUMAN
NC score	0.014309 (rank : 75)	θ value	8.99809 (rank : 85)
Query Neighborhood Hits	92	Target Neighborhood Hits	337	Shared Neighborhood Hits	17
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

PPHLN_MOUSE
NC score	0.013525 (rank : 76)	θ value	8.99809 (rank : 87)
Query Neighborhood Hits	92	Target Neighborhood Hits	41	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K2H1, Q8BUZ6	Gene names	Pphln1
Domain Architecture	No domain graphic available
Description	Periphilin-1.

ANK2_HUMAN
NC score	0.012796 (rank : 77)	θ value	4.03905 (rank : 66)
Query Neighborhood Hits	92	Target Neighborhood Hits	1615	Shared Neighborhood Hits	29
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

MYH10_HUMAN
NC score	0.012761 (rank : 78)	θ value	0.0961366 (rank : 25)
Query Neighborhood Hits	92	Target Neighborhood Hits	1620	Shared Neighborhood Hits	22
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH10_MOUSE
NC score	0.011589 (rank : 79)	θ value	0.62314 (rank : 41)
Query Neighborhood Hits	92	Target Neighborhood Hits	1612	Shared Neighborhood Hits	24
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

TARA_HUMAN
NC score	0.011328 (rank : 80)	θ value	8.99809 (rank : 91)
Query Neighborhood Hits	92	Target Neighborhood Hits	1626	Shared Neighborhood Hits	26
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

SMBT1_HUMAN
NC score	0.010652 (rank : 81)	θ value	5.27518 (rank : 76)
Query Neighborhood Hits	92	Target Neighborhood Hits	53	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UHJ3, Q96C73, Q9Y4Q9	Gene names	SFMBT1, RU1
Domain Architecture	No domain graphic available
Description	Scm-like with four MBT domains protein 1 (Renal ubiquitous protein 1).

RPGR1_HUMAN
NC score	0.010023 (rank : 82)	θ value	8.99809 (rank : 89)
Query Neighborhood Hits	92	Target Neighborhood Hits	578	Shared Neighborhood Hits	14
SwissProt Accessions	Q96KN7, Q7Z2W6, Q8IXV5, Q96QA8, Q9HB94, Q9HB95, Q9HBK6, Q9NR40	Gene names	RPGRIP1
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

ERC2_HUMAN
NC score	0.009668 (rank : 83)	θ value	5.27518 (rank : 73)
Query Neighborhood Hits	92	Target Neighborhood Hits	1156	Shared Neighborhood Hits	17
SwissProt Accessions	O15083, Q86TK4	Gene names	ERC2, KIAA0378
Domain Architecture	No domain graphic available
Description	ERC protein 2.

HOOK1_MOUSE
NC score	0.009460 (rank : 84)	θ value	6.88961 (rank : 80)
Query Neighborhood Hits	92	Target Neighborhood Hits	910	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BIL5, Q8BIZ2, Q8K0P1, Q8K454, Q9CTN6	Gene names	Hook1
Domain Architecture
Description	Hook homolog 1.

HOOK1_HUMAN
NC score	0.009306 (rank : 85)	θ value	6.88961 (rank : 79)
Query Neighborhood Hits	92	Target Neighborhood Hits	942	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UJC3, O60561, Q5TG44	Gene names	HOOK1
Domain Architecture
Description	Hook homolog 1 (h-hook1) (hHK1).

ERC2_MOUSE
NC score	0.008503 (rank : 86)	θ value	8.99809 (rank : 86)
Query Neighborhood Hits	92	Target Neighborhood Hits	1166	Shared Neighborhood Hits	16
SwissProt Accessions	Q6PH08, Q80U20, Q8CCP1	Gene names	Erc2, Cast1, D14Ertd171e, Kiaa0378
Domain Architecture	No domain graphic available
Description	ERC protein 2 (CAZ-associated structural protein 1) (CAST1).

LAMB1_HUMAN
NC score	0.008397 (rank : 87)	θ value	2.36792 (rank : 60)
Query Neighborhood Hits	92	Target Neighborhood Hits	1018	Shared Neighborhood Hits	16
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

K1802_HUMAN
NC score	0.008304 (rank : 88)	θ value	1.81305 (rank : 52)
Query Neighborhood Hits	92	Target Neighborhood Hits	1378	Shared Neighborhood Hits	12
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

MYPC2_MOUSE
NC score	0.004580 (rank : 89)	θ value	5.27518 (rank : 74)
Query Neighborhood Hits	92	Target Neighborhood Hits	297	Shared Neighborhood Hits	3
SwissProt Accessions	Q5XKE0, Q8C109, Q8K2V0	Gene names	Mybpc2
Domain Architecture	No domain graphic available
Description	Myosin-binding protein C, fast-type (Fast MyBP-C) (C-protein, skeletal muscle fast isoform).

EMR3_HUMAN
NC score	0.003895 (rank : 90)	θ value	5.27518 (rank : 72)
Query Neighborhood Hits	92	Target Neighborhood Hits	245	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BY15	Gene names	EMR3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 3 precursor (EGF-like module-containing mucin-like receptor EMR3).

CSPG3_MOUSE
NC score	0.003755 (rank : 91)	θ value	5.27518 (rank : 70)
Query Neighborhood Hits	92	Target Neighborhood Hits	657	Shared Neighborhood Hits	9
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

LRFN5_MOUSE
NC score	0.001167 (rank : 92)	θ value	6.88961 (rank : 81)
Query Neighborhood Hits	92	Target Neighborhood Hits	472	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BXA0, Q8BJH4, Q8BZL0	Gene names	Lrfn5
Domain Architecture
Description	Leucine-rich repeat and fibronectin type-III domain-containing protein 5 precursor.