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Network neighborhood for query Sequence : ITPR3_HUMAN

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ITPR3_HUMAN
SwissProt Accessions	Q14573, Q14649	Gene names	ITPR3
Domain Architecture
Description	Inositol 1,4,5-trisphosphate receptor type 3 (Type 3 inositol 1,4,5- trisphosphate receptor) (Type 3 InsP3 receptor) (IP3 receptor isoform 3) (InsP3R3).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ITPR1_HUMAN
θ value	0 (rank : 1)	NC score	0.989276 (rank : 5)
Query Neighborhood Hits	114	Target Neighborhood Hits	90	Shared Neighborhood Hits	22
SwissProt Accessions	Q14643, Q14660, Q99897	Gene names	ITPR1, INSP3R1
Domain Architecture
Description	Inositol 1,4,5-trisphosphate receptor type 1 (Type 1 inositol 1,4,5- trisphosphate receptor) (Type 1 InsP3 receptor) (IP3 receptor isoform 1) (InsP3R1) (IP3R).

ITPR1_MOUSE
θ value	0 (rank : 2)	NC score	0.988722 (rank : 6)
Query Neighborhood Hits	114	Target Neighborhood Hits	99	Shared Neighborhood Hits	22
SwissProt Accessions	P11881, P20943, Q99LG5	Gene names	Itpr1, Insp3r, Pcd6, Pcp1
Domain Architecture
Description	Inositol 1,4,5-trisphosphate receptor type 1 (Type 1 inositol 1,4,5- trisphosphate receptor) (Type 1 InsP3 receptor) (IP3 receptor isoform 1) (InsP3R1) (Inositol 1,4,5-trisphosphate-binding protein P400) (Purkinje cell protein 1) (Protein PCD-6).

ITPR2_HUMAN
θ value	0 (rank : 3)	NC score	0.990631 (rank : 4)
Query Neighborhood Hits	114	Target Neighborhood Hits	74	Shared Neighborhood Hits	19
SwissProt Accessions	Q14571, O94773	Gene names	ITPR2
Domain Architecture
Description	Inositol 1,4,5-trisphosphate receptor type 2 (Type 2 inositol 1,4,5- trisphosphate receptor) (Type 2 InsP3 receptor) (IP3 receptor isoform 2) (InsP3R2).

ITPR2_MOUSE
θ value	0 (rank : 4)	NC score	0.991022 (rank : 3)
Query Neighborhood Hits	114	Target Neighborhood Hits	69	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Z329, P70226, Q5DWM3, Q5DWM5, Q61744, Q8R3B0	Gene names	Itpr2, Itpr5
Domain Architecture	No domain graphic available
Description	Inositol 1,4,5-trisphosphate receptor type 2 (Type 2 inositol 1,4,5- trisphosphate receptor) (Type 2 InsP3 receptor) (IP3 receptor isoform 2) (InsP3R2) (Inositol 1,4,5-trisphosphate type V receptor).

ITPR3_HUMAN
θ value	0 (rank : 5)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	114	Target Neighborhood Hits	114	Shared Neighborhood Hits	114
SwissProt Accessions	Q14573, Q14649	Gene names	ITPR3
Domain Architecture
Description	Inositol 1,4,5-trisphosphate receptor type 3 (Type 3 inositol 1,4,5- trisphosphate receptor) (Type 3 InsP3 receptor) (IP3 receptor isoform 3) (InsP3R3).

ITPR3_MOUSE
θ value	0 (rank : 6)	NC score	0.997177 (rank : 2)
Query Neighborhood Hits	114	Target Neighborhood Hits	105	Shared Neighborhood Hits	75
SwissProt Accessions	P70227, Q5DWM4, Q8CED5, Q91Z08	Gene names	Itpr3
Domain Architecture	No domain graphic available
Description	Inositol 1,4,5-trisphosphate receptor type 3 (Type 3 inositol 1,4,5- trisphosphate receptor) (Type 3 InsP3 receptor) (IP3 receptor isoform 3) (InsP3R3).

RYR2_HUMAN
θ value	3.50572e-28 (rank : 7)	NC score	0.532386 (rank : 9)
Query Neighborhood Hits	114	Target Neighborhood Hits	175	Shared Neighborhood Hits	15
SwissProt Accessions	Q92736, Q15411, Q546N8	Gene names	RYR2
Domain Architecture
Description	Ryanodine receptor 2 (Cardiac muscle-type ryanodine receptor) (RyR2) (RYR-2) (Cardiac muscle ryanodine receptor-calcium release channel) (hRYR-2).

RYR1_HUMAN
θ value	4.57862e-28 (rank : 8)	NC score	0.536980 (rank : 8)
Query Neighborhood Hits	114	Target Neighborhood Hits	303	Shared Neighborhood Hits	18
SwissProt Accessions	P21817, Q16314, Q16368, Q9NPK1, Q9P1U4	Gene names	RYR1, RYDR
Domain Architecture
Description	Ryanodine receptor 1 (Skeletal muscle-type ryanodine receptor) (RyR1) (RYR-1) (Skeletal muscle calcium release channel).

RYR3_HUMAN
θ value	1.33217e-27 (rank : 9)	NC score	0.542713 (rank : 7)
Query Neighborhood Hits	114	Target Neighborhood Hits	134	Shared Neighborhood Hits	13
SwissProt Accessions	Q15413, O15175, Q15412	Gene names	RYR3, HBRR
Domain Architecture
Description	Ryanodine receptor 3 (Brain-type ryanodine receptor) (RyR3) (RYR-3) (Brain ryanodine receptor-calcium release channel).

OPTN_MOUSE
θ value	0.0148317 (rank : 10)	NC score	0.053057 (rank : 10)
Query Neighborhood Hits	114	Target Neighborhood Hits	1120	Shared Neighborhood Hits	68
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

SYTL4_MOUSE
θ value	0.0563607 (rank : 11)	NC score	0.017333 (rank : 86)
Query Neighborhood Hits	114	Target Neighborhood Hits	137	Shared Neighborhood Hits	4
SwissProt Accessions	Q9R0Q1, Q8R321, Q9R0Q0	Gene names	Sytl4, Slp4
Domain Architecture
Description	Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin).

GOGA4_HUMAN
θ value	0.0961366 (rank : 12)	NC score	0.046815 (rank : 14)
Query Neighborhood Hits	114	Target Neighborhood Hits	2034	Shared Neighborhood Hits	75
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

CNGA1_MOUSE
θ value	0.125558 (rank : 13)	NC score	0.016479 (rank : 87)
Query Neighborhood Hits	114	Target Neighborhood Hits	198	Shared Neighborhood Hits	12
SwissProt Accessions	P29974, Q60776	Gene names	Cnga1, Cncg, Cncg1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

GCC2_HUMAN
θ value	0.21417 (rank : 14)	NC score	0.039053 (rank : 19)
Query Neighborhood Hits	114	Target Neighborhood Hits	1558	Shared Neighborhood Hits	68
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

RBP24_HUMAN
θ value	0.21417 (rank : 15)	NC score	0.039116 (rank : 18)
Query Neighborhood Hits	114	Target Neighborhood Hits	1559	Shared Neighborhood Hits	68
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

CEP57_MOUSE
θ value	0.365318 (rank : 16)	NC score	0.038337 (rank : 20)
Query Neighborhood Hits	114	Target Neighborhood Hits	580	Shared Neighborhood Hits	58
SwissProt Accessions	Q8CEE0, Q6ZQJ3, Q7TN18, Q80X65, Q810F2, Q9D4J4, Q9D5S4, Q9D5W5	Gene names	Cep57, Kiaa0092, Tsp57
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 57 kDa (Cep57 protein) (Testis-specific protein 57) (Translokin).

GOGB1_HUMAN
θ value	0.365318 (rank : 17)	NC score	0.040097 (rank : 17)
Query Neighborhood Hits	114	Target Neighborhood Hits	2297	Shared Neighborhood Hits	77
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

MYH11_MOUSE
θ value	0.365318 (rank : 18)	NC score	0.032552 (rank : 37)
Query Neighborhood Hits	114	Target Neighborhood Hits	1777	Shared Neighborhood Hits	77
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

PAIP1_MOUSE
θ value	0.365318 (rank : 19)	NC score	0.047374 (rank : 13)
Query Neighborhood Hits	114	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VE62, Q9WUC9	Gene names	Paip1
Domain Architecture
Description	Polyadenylate-binding protein-interacting protein 1 (Poly(A)-binding protein-interacting protein 1) (PABP-interacting protein 1) (PAIP-1).

ROCK1_MOUSE
θ value	0.365318 (rank : 20)	NC score	0.021875 (rank : 71)
Query Neighborhood Hits	114	Target Neighborhood Hits	2126	Shared Neighborhood Hits	73
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

CENPF_HUMAN
θ value	0.47712 (rank : 21)	NC score	0.035378 (rank : 28)
Query Neighborhood Hits	114	Target Neighborhood Hits	1932	Shared Neighborhood Hits	72
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

KINH_HUMAN
θ value	0.47712 (rank : 22)	NC score	0.026460 (rank : 62)
Query Neighborhood Hits	114	Target Neighborhood Hits	1231	Shared Neighborhood Hits	69
SwissProt Accessions	P33176, Q5VZ85	Gene names	KIF5B, KNS, KNS1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

TPR_HUMAN
θ value	0.47712 (rank : 23)	NC score	0.035437 (rank : 27)
Query Neighborhood Hits	114	Target Neighborhood Hits	1921	Shared Neighborhood Hits	67
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

VIME_HUMAN
θ value	0.47712 (rank : 24)	NC score	0.020795 (rank : 72)
Query Neighborhood Hits	114	Target Neighborhood Hits	706	Shared Neighborhood Hits	59
SwissProt Accessions	P08670, Q15867, Q15868, Q15869, Q6LER9, Q8N850, Q96ML2, Q9NTM3	Gene names	VIM
Domain Architecture
Description	Vimentin.

ANR26_MOUSE
θ value	0.813845 (rank : 25)	NC score	0.033213 (rank : 34)
Query Neighborhood Hits	114	Target Neighborhood Hits	1554	Shared Neighborhood Hits	72
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

EP15_HUMAN
θ value	0.813845 (rank : 26)	NC score	0.047385 (rank : 12)
Query Neighborhood Hits	114	Target Neighborhood Hits	1021	Shared Neighborhood Hits	69
SwissProt Accessions	P42566	Gene names	EPS15, AF1P
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

GP158_MOUSE
θ value	0.813845 (rank : 27)	NC score	0.032764 (rank : 35)
Query Neighborhood Hits	114	Target Neighborhood Hits	82	Shared Neighborhood Hits	7
SwissProt Accessions	Q8C419, Q8CHB0	Gene names	Gpr158, Kiaa1136
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 158 precursor.

MYH9_MOUSE
θ value	0.813845 (rank : 28)	NC score	0.027990 (rank : 51)
Query Neighborhood Hits	114	Target Neighborhood Hits	1829	Shared Neighborhood Hits	73
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

OXRP_HUMAN
θ value	0.813845 (rank : 29)	NC score	0.020748 (rank : 73)
Query Neighborhood Hits	114	Target Neighborhood Hits	544	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

ROCK1_HUMAN
θ value	0.813845 (rank : 30)	NC score	0.019584 (rank : 80)
Query Neighborhood Hits	114	Target Neighborhood Hits	2000	Shared Neighborhood Hits	69
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).

WDHD1_HUMAN
θ value	0.813845 (rank : 31)	NC score	0.020218 (rank : 76)
Query Neighborhood Hits	114	Target Neighborhood Hits	342	Shared Neighborhood Hits	6
SwissProt Accessions	O75717	Gene names	WDHD1, AND1
Domain Architecture
Description	WD repeat and HMG-box DNA-binding protein 1 (Acidic nucleoplasmic DNA- binding protein 1) (And-1).

CBX4_HUMAN
θ value	1.06291 (rank : 32)	NC score	0.014916 (rank : 91)
Query Neighborhood Hits	114	Target Neighborhood Hits	68	Shared Neighborhood Hits	2
SwissProt Accessions	O00257, Q96C04	Gene names	CBX4
Domain Architecture
Description	Chromobox protein homolog 4 (Polycomb 2 homolog) (Pc2) (hPc2).

CP250_MOUSE
θ value	1.06291 (rank : 33)	NC score	0.036716 (rank : 24)
Query Neighborhood Hits	114	Target Neighborhood Hits	1583	Shared Neighborhood Hits	73
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

MYH14_MOUSE
θ value	1.06291 (rank : 34)	NC score	0.034389 (rank : 30)
Query Neighborhood Hits	114	Target Neighborhood Hits	1225	Shared Neighborhood Hits	71
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

CTRO_HUMAN
θ value	1.38821 (rank : 35)	NC score	0.019939 (rank : 79)
Query Neighborhood Hits	114	Target Neighborhood Hits	2092	Shared Neighborhood Hits	71
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

ENAH_HUMAN
θ value	1.38821 (rank : 36)	NC score	0.025073 (rank : 66)
Query Neighborhood Hits	114	Target Neighborhood Hits	784	Shared Neighborhood Hits	55
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

LRC45_MOUSE
θ value	1.38821 (rank : 37)	NC score	0.044214 (rank : 15)
Query Neighborhood Hits	114	Target Neighborhood Hits	959	Shared Neighborhood Hits	67
SwissProt Accessions	Q8CIM1, Q3U5Z2	Gene names	Lrrc45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

PAIP1_HUMAN
θ value	1.38821 (rank : 38)	NC score	0.037047 (rank : 23)
Query Neighborhood Hits	114	Target Neighborhood Hits	76	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H074, O60455, Q96B61, Q9BS63	Gene names	PAIP1
Domain Architecture
Description	Polyadenylate-binding protein-interacting protein 1 (Poly(A)-binding protein-interacting protein 1) (PABP-interacting protein 1) (PAIP-1).

CJ118_MOUSE
θ value	1.81305 (rank : 39)	NC score	0.050991 (rank : 11)
Query Neighborhood Hits	114	Target Neighborhood Hits	1132	Shared Neighborhood Hits	71
SwissProt Accessions	Q8C9S4, Q6P3D6, Q8CJC0	Gene names	Otg1
Domain Architecture	No domain graphic available
Description	Protein C10orf118 homolog (Oocyte-testis gene 1 protein).

CN145_HUMAN
θ value	1.81305 (rank : 40)	NC score	0.035716 (rank : 26)
Query Neighborhood Hits	114	Target Neighborhood Hits	1196	Shared Neighborhood Hits	69
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

KINH_MOUSE
θ value	1.81305 (rank : 41)	NC score	0.025388 (rank : 65)
Query Neighborhood Hits	114	Target Neighborhood Hits	1082	Shared Neighborhood Hits	67
SwissProt Accessions	Q61768, O08711, Q61580	Gene names	Kif5b, Khcs, Kns1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

RUFY1_HUMAN
θ value	1.81305 (rank : 42)	NC score	0.029969 (rank : 45)
Query Neighborhood Hits	114	Target Neighborhood Hits	848	Shared Neighborhood Hits	63
SwissProt Accessions	Q96T51, Q59FF3, Q71S93, Q9H6I3	Gene names	RUFY1, RABIP4, ZFYVE12
Domain Architecture
Description	RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (Zinc finger FYVE domain-containing protein 12) (La-binding protein 1) (Rab4-interacting protein).

CTR9_HUMAN
θ value	2.36792 (rank : 43)	NC score	0.015789 (rank : 90)
Query Neighborhood Hits	114	Target Neighborhood Hits	383	Shared Neighborhood Hits	24
SwissProt Accessions	Q6PD62, Q15015	Gene names	CTR9, KIAA0155, SH2BP1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1).

CTRO_MOUSE
θ value	2.36792 (rank : 44)	NC score	0.019330 (rank : 81)
Query Neighborhood Hits	114	Target Neighborhood Hits	2344	Shared Neighborhood Hits	72
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

GBGT2_HUMAN
θ value	2.36792 (rank : 45)	NC score	0.030111 (rank : 44)
Query Neighborhood Hits	114	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	O14610	Gene names	GNGT2, GNG8, GNG9, GNGT8
Domain Architecture
Description	Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-T2 subunit precursor (G gamma-C) (G-gamma-8) (G-gamma 9).

GCP6_HUMAN
θ value	2.36792 (rank : 46)	NC score	0.029958 (rank : 46)
Query Neighborhood Hits	114	Target Neighborhood Hits	295	Shared Neighborhood Hits	27
SwissProt Accessions	Q96RT7, Q5JZ80, Q6PJ40, Q86YE9, Q9BY91, Q9UGX3, Q9UGX4	Gene names	TUBGCP6, GCP6, KIAA1669
Domain Architecture
Description	Gamma-tubulin complex component 6 (GCP-6).

LRC45_HUMAN
θ value	2.36792 (rank : 47)	NC score	0.037053 (rank : 22)
Query Neighborhood Hits	114	Target Neighborhood Hits	933	Shared Neighborhood Hits	64
SwissProt Accessions	Q96CN5	Gene names	LRRC45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

SMCA2_HUMAN
θ value	2.36792 (rank : 48)	NC score	0.011673 (rank : 96)
Query Neighborhood Hits	114	Target Neighborhood Hits	503	Shared Neighborhood Hits	24
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

ABCAD_HUMAN
θ value	3.0926 (rank : 49)	NC score	0.007887 (rank : 102)
Query Neighborhood Hits	114	Target Neighborhood Hits	207	Shared Neighborhood Hits	6
SwissProt Accessions	Q86UQ4, Q6ZTT7, Q86WI2, Q8N248	Gene names	ABCA13
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 13.

CF010_HUMAN
θ value	3.0926 (rank : 50)	NC score	0.020078 (rank : 77)
Query Neighborhood Hits	114	Target Neighborhood Hits	329	Shared Neighborhood Hits	17
SwissProt Accessions	Q5SRN2, Q5SPI9, Q5SPJ0, Q5SPK9, Q5SPL0, Q5SRN3, Q5TG25, Q5TG26, Q8N4B6	Gene names	C6orf10
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf10.

CT2NL_MOUSE
θ value	3.0926 (rank : 51)	NC score	0.032326 (rank : 39)
Query Neighborhood Hits	114	Target Neighborhood Hits	902	Shared Neighborhood Hits	67
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

DNMT1_HUMAN
θ value	3.0926 (rank : 52)	NC score	0.014630 (rank : 92)
Query Neighborhood Hits	114	Target Neighborhood Hits	401	Shared Neighborhood Hits	24
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

GP158_HUMAN
θ value	3.0926 (rank : 53)	NC score	0.024214 (rank : 67)
Query Neighborhood Hits	114	Target Neighborhood Hits	221	Shared Neighborhood Hits	9
SwissProt Accessions	Q5T848, Q6QR81, Q9ULT3	Gene names	GPR158, KIAA1136
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 158 precursor.

HOOK3_MOUSE
θ value	3.0926 (rank : 54)	NC score	0.033429 (rank : 32)
Query Neighborhood Hits	114	Target Neighborhood Hits	1007	Shared Neighborhood Hits	64
SwissProt Accessions	Q8BUK6, Q8BV48, Q8BW57, Q8BY41	Gene names	Hook3
Domain Architecture
Description	Hook homolog 3.

INT2_MOUSE
θ value	3.0926 (rank : 55)	NC score	0.020409 (rank : 75)
Query Neighborhood Hits	114	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q80UK8, Q5SXZ5, Q5SXZ6, Q6PCY7, Q6ZPU6, Q8CB15, Q9CSE0	Gene names	Ints2, Kiaa1287
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 2 (Int2).

PCNT_HUMAN
θ value	3.0926 (rank : 56)	NC score	0.032589 (rank : 36)
Query Neighborhood Hits	114	Target Neighborhood Hits	1551	Shared Neighborhood Hits	69
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

RRP44_HUMAN
θ value	3.0926 (rank : 57)	NC score	0.027200 (rank : 56)
Query Neighborhood Hits	114	Target Neighborhood Hits	35	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y2L1, Q5W0P7, Q5W0P8, Q658Z7, Q7Z481, Q8WWI2, Q9UG36	Gene names	DIS3, KIAA1008, RRP44
Domain Architecture
Description	Exosome complex exonuclease RRP44 (EC 3.1.13.-) (Ribosomal RNA- processing protein 44) (DIS3 protein homolog).

TTLL5_MOUSE
θ value	3.0926 (rank : 58)	NC score	0.020606 (rank : 74)
Query Neighborhood Hits	114	Target Neighborhood Hits	150	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CHB8	Gene names	Ttll5, Kiaa0998
Domain Architecture	No domain graphic available
Description	Tubulin--tyrosine ligase-like protein 5.

APHC_HUMAN
θ value	4.03905 (rank : 59)	NC score	0.029786 (rank : 47)
Query Neighborhood Hits	114	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NUN7	Gene names	PHCA, APHC
Domain Architecture
Description	Alkaline phytoceramidase (EC 3.5.1.-) (aPHC) (Alkaline ceramidase) (Alkaline dihydroceramidase SB89).

CE152_HUMAN
θ value	4.03905 (rank : 60)	NC score	0.037532 (rank : 21)
Query Neighborhood Hits	114	Target Neighborhood Hits	976	Shared Neighborhood Hits	65
SwissProt Accessions	O94986, Q6NTA0	Gene names	CEP152, KIAA0912
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 152 kDa (Cep152 protein).

CJ068_HUMAN
θ value	4.03905 (rank : 61)	NC score	0.033634 (rank : 31)
Query Neighborhood Hits	114	Target Neighborhood Hits	316	Shared Neighborhood Hits	36
SwissProt Accessions	Q9H943, Q8N7T7	Gene names	C10orf68
Domain Architecture	No domain graphic available
Description	Protein C10orf68.

CN145_MOUSE
θ value	4.03905 (rank : 62)	NC score	0.034519 (rank : 29)
Query Neighborhood Hits	114	Target Neighborhood Hits	916	Shared Neighborhood Hits	62
SwissProt Accessions	Q8BI22	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf145 homolog.

ERF1_HUMAN
θ value	4.03905 (rank : 63)	NC score	0.018925 (rank : 83)
Query Neighborhood Hits	114	Target Neighborhood Hits	13	Shared Neighborhood Hits	4
SwissProt Accessions	P62495, P46055, Q5M7Z7	Gene names	ETF1, ERF1, RF1
Domain Architecture	No domain graphic available
Description	Eukaryotic peptide chain release factor subunit 1 (eRF1) (Eukaryotic release factor 1) (TB3-1) (Cl1 protein).

ERF1_MOUSE
θ value	4.03905 (rank : 64)	NC score	0.018925 (rank : 84)
Query Neighborhood Hits	114	Target Neighborhood Hits	13	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BWY3, Q3TPZ6, Q91VH9	Gene names	Etf1
Domain Architecture	No domain graphic available
Description	Eukaryotic peptide chain release factor subunit 1 (eRF1) (Eukaryotic release factor 1).

HOOK3_HUMAN
θ value	4.03905 (rank : 65)	NC score	0.032429 (rank : 38)
Query Neighborhood Hits	114	Target Neighborhood Hits	1070	Shared Neighborhood Hits	63
SwissProt Accessions	Q86VS8, Q8NBH0, Q9BY13	Gene names	HOOK3
Domain Architecture
Description	Hook homolog 3 (hHK3).

MY18A_HUMAN
θ value	4.03905 (rank : 66)	NC score	0.026899 (rank : 59)
Query Neighborhood Hits	114	Target Neighborhood Hits	1929	Shared Neighborhood Hits	69
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MY18A_MOUSE
θ value	4.03905 (rank : 67)	NC score	0.027143 (rank : 57)
Query Neighborhood Hits	114	Target Neighborhood Hits	1989	Shared Neighborhood Hits	71
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

MYH10_MOUSE
θ value	4.03905 (rank : 68)	NC score	0.029027 (rank : 48)
Query Neighborhood Hits	114	Target Neighborhood Hits	1612	Shared Neighborhood Hits	69
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH11_HUMAN
θ value	4.03905 (rank : 69)	NC score	0.028417 (rank : 50)
Query Neighborhood Hits	114	Target Neighborhood Hits	1806	Shared Neighborhood Hits	75
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYO5B_HUMAN
θ value	4.03905 (rank : 70)	NC score	0.022736 (rank : 69)
Query Neighborhood Hits	114	Target Neighborhood Hits	911	Shared Neighborhood Hits	62
SwissProt Accessions	Q9ULV0	Gene names	MYO5B, KIAA1119
Domain Architecture
Description	Myosin-5B (Myosin Vb).

NPAL3_MOUSE
θ value	4.03905 (rank : 71)	NC score	0.019962 (rank : 78)
Query Neighborhood Hits	114	Target Neighborhood Hits	17	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BGN5, Q6PG85, Q9D2Y2	Gene names	Npal3
Domain Architecture	No domain graphic available
Description	NIPA-like protein 3.

RAI14_MOUSE
θ value	4.03905 (rank : 72)	NC score	0.025820 (rank : 64)
Query Neighborhood Hits	114	Target Neighborhood Hits	1505	Shared Neighborhood Hits	69
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

SYTL4_HUMAN
θ value	4.03905 (rank : 73)	NC score	0.010921 (rank : 97)
Query Neighborhood Hits	114	Target Neighborhood Hits	138	Shared Neighborhood Hits	5
SwissProt Accessions	Q96C24, Q5H9J3, Q5JPG8, Q8N9P4, Q9H4R0, Q9H4R1	Gene names	SYTL4
Domain Architecture
Description	Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin).

TXD13_HUMAN
θ value	4.03905 (rank : 74)	NC score	0.012882 (rank : 94)
Query Neighborhood Hits	114	Target Neighborhood Hits	106	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H1E5, Q8N4P7, Q8NCC1, Q9UJA1, Q9ULQ8	Gene names	TXNDC13, KIAA1162
Domain Architecture
Description	Thioredoxin domain-containing protein 13 precursor.

ZEP2_MOUSE
θ value	4.03905 (rank : 75)	NC score	0.000760 (rank : 113)
Query Neighborhood Hits	114	Target Neighborhood Hits	964	Shared Neighborhood Hits	9
SwissProt Accessions	Q3UHF7, O55140, Q3UVD4, Q3UVH5	Gene names	Hivep2, Mibp1
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 homolog (Myc intron-binding protein 1) (MIBP-1).

AKAP9_HUMAN
θ value	5.27518 (rank : 76)	NC score	0.031541 (rank : 40)
Query Neighborhood Hits	114	Target Neighborhood Hits	1710	Shared Neighborhood Hits	69
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

CE290_HUMAN
θ value	5.27518 (rank : 77)	NC score	0.031023 (rank : 42)
Query Neighborhood Hits	114	Target Neighborhood Hits	1553	Shared Neighborhood Hits	70
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

TNIK_HUMAN
θ value	5.27518 (rank : 78)	NC score	0.005064 (rank : 108)
Query Neighborhood Hits	114	Target Neighborhood Hits	1570	Shared Neighborhood Hits	56
SwissProt Accessions	Q9UKE5, O60298, Q8WUY7, Q9UKD8, Q9UKD9, Q9UKE0, Q9UKE1, Q9UKE2, Q9UKE3, Q9UKE4	Gene names	TNIK, KIAA0551
Domain Architecture
Description	TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1).

BCAS4_HUMAN
θ value	6.88961 (rank : 79)	NC score	0.012135 (rank : 95)
Query Neighborhood Hits	114	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TDM0, Q5TD52, Q5TD53, Q5TD54, Q5U5K7, Q5XKE8, Q8IXI7, Q8NEZ6, Q8TDL9, Q9NX13, Q9Y511	Gene names	BCAS4
Domain Architecture	No domain graphic available
Description	Breast carcinoma amplified sequence 4.

CECR2_HUMAN
θ value	6.88961 (rank : 80)	NC score	0.009645 (rank : 100)
Query Neighborhood Hits	114	Target Neighborhood Hits	543	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

CNGA1_HUMAN
θ value	6.88961 (rank : 81)	NC score	0.009800 (rank : 99)
Query Neighborhood Hits	114	Target Neighborhood Hits	149	Shared Neighborhood Hits	7
SwissProt Accessions	P29973, Q16279, Q16485	Gene names	CNGA1, CNCG, CNCG1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

COVA1_HUMAN
θ value	6.88961 (rank : 82)	NC score	0.026961 (rank : 58)
Query Neighborhood Hits	114	Target Neighborhood Hits	416	Shared Neighborhood Hits	50
SwissProt Accessions	Q16206, Q5VTJ1, Q5VTJ2, Q8WUX0, Q9NTP6, Q9UH82	Gene names	COVA1
Domain Architecture
Description	Tumor-associated hydroquinone oxidase (tNOX) (Cytosolic ovarian carcinoma antigen 1) (APK1 antigen) [Includes: Hydroquinone [NADH] oxidase (EC 1.-.-.-); Protein disulfide-thiol oxidoreductase (EC 1.-.-.-)].

DHX16_HUMAN
θ value	6.88961 (rank : 83)	NC score	0.010418 (rank : 98)
Query Neighborhood Hits	114	Target Neighborhood Hits	356	Shared Neighborhood Hits	36
SwissProt Accessions	O60231, O60322, Q969X7, Q96QC1	Gene names	DHX16, DBP2, DDX16, KIAA0577
Domain Architecture
Description	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 (EC 3.6.1.-) (DEAH-box protein 16) (ATP-dependent RNA helicase #3).

DMD_HUMAN
θ value	6.88961 (rank : 84)	NC score	0.030456 (rank : 43)
Query Neighborhood Hits	114	Target Neighborhood Hits	1135	Shared Neighborhood Hits	71
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

FRAS1_HUMAN
θ value	6.88961 (rank : 85)	NC score	0.001576 (rank : 111)
Query Neighborhood Hits	114	Target Neighborhood Hits	759	Shared Neighborhood Hits	5
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

GTR2_HUMAN
θ value	6.88961 (rank : 86)	NC score	0.006517 (rank : 104)
Query Neighborhood Hits	114	Target Neighborhood Hits	40	Shared Neighborhood Hits	3
SwissProt Accessions	P11168	Gene names	SLC2A2, GLUT2
Domain Architecture
Description	Solute carrier family 2, facilitated glucose transporter member 2 (Glucose transporter type 2, liver).

HIPK1_HUMAN
θ value	6.88961 (rank : 87)	NC score	0.000921 (rank : 112)
Query Neighborhood Hits	114	Target Neighborhood Hits	843	Shared Neighborhood Hits	9
SwissProt Accessions	Q86Z02, O75125, Q8IYD7, Q8NDN5, Q8NEB6, Q8TBZ1	Gene names	HIPK1, KIAA0630
Domain Architecture
Description	Homeodomain-interacting protein kinase 1 (EC 2.7.11.1).

KGP2_HUMAN
θ value	6.88961 (rank : 88)	NC score	0.002976 (rank : 110)
Query Neighborhood Hits	114	Target Neighborhood Hits	1023	Shared Neighborhood Hits	35
SwissProt Accessions	Q13237, O00125, O60916	Gene names	PRKG2, PRKGR2
Domain Architecture
Description	cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).

KI21A_MOUSE
θ value	6.88961 (rank : 89)	NC score	0.016125 (rank : 89)
Query Neighborhood Hits	114	Target Neighborhood Hits	1317	Shared Neighborhood Hits	65
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

LAMB1_HUMAN
θ value	6.88961 (rank : 90)	NC score	0.018805 (rank : 85)
Query Neighborhood Hits	114	Target Neighborhood Hits	1018	Shared Neighborhood Hits	59
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

LUZP1_MOUSE
θ value	6.88961 (rank : 91)	NC score	0.027801 (rank : 53)
Query Neighborhood Hits	114	Target Neighborhood Hits	940	Shared Neighborhood Hits	65
SwissProt Accessions	Q8R4U7, Q3UV18, Q7TS71, Q8BQW1, Q99NG3, Q9CSL6	Gene names	Luzp1, Luzp
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1 (Leucine zipper motif-containing protein).

MD1L1_HUMAN
θ value	6.88961 (rank : 92)	NC score	0.033225 (rank : 33)
Query Neighborhood Hits	114	Target Neighborhood Hits	893	Shared Neighborhood Hits	63
SwissProt Accessions	Q9Y6D9, Q13312, Q75MI0, Q86UM4, Q9UNH0	Gene names	MAD1L1, MAD1, TXBP181
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1) (Mitotic checkpoint MAD1 protein-homolog) (HsMAD1) (hMAD1) (Tax-binding protein 181).

MLL3_MOUSE
θ value	6.88961 (rank : 93)	NC score	0.005115 (rank : 107)
Query Neighborhood Hits	114	Target Neighborhood Hits	1399	Shared Neighborhood Hits	29
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

MYH6_MOUSE
θ value	6.88961 (rank : 94)	NC score	0.027246 (rank : 55)
Query Neighborhood Hits	114	Target Neighborhood Hits	1501	Shared Neighborhood Hits	72
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

NPAL3_HUMAN
θ value	6.88961 (rank : 95)	NC score	0.016357 (rank : 88)
Query Neighborhood Hits	114	Target Neighborhood Hits	13	Shared Neighborhood Hits	4
SwissProt Accessions	Q6P499, Q6MZT9, Q9BVE6	Gene names	NPAL3
Domain Architecture	No domain graphic available
Description	NIPA-like protein 3.

NUF2_HUMAN
θ value	6.88961 (rank : 96)	NC score	0.036304 (rank : 25)
Query Neighborhood Hits	114	Target Neighborhood Hits	661	Shared Neighborhood Hits	61
SwissProt Accessions	Q9BZD4, Q8WU69, Q96HJ4, Q96Q78	Gene names	CDCA1, NUF2, NUF2R
Domain Architecture	No domain graphic available
Description	Kinetochore protein Nuf2 (hNuf2) (hNuf2R) (hsNuf2) (Cell division cycle-associated protein 1).

OLR1_MOUSE
θ value	6.88961 (rank : 97)	NC score	0.024196 (rank : 68)
Query Neighborhood Hits	114	Target Neighborhood Hits	596	Shared Neighborhood Hits	49
SwissProt Accessions	Q9EQ09	Gene names	Olr1, Lox1
Domain Architecture	No domain graphic available
Description	Oxidized low-density lipoprotein receptor 1 (Ox-LDL receptor 1) (Lectin-type oxidized LDL receptor 1) (Lectin-like oxidized LDL receptor 1) (Lectin-like oxLDL receptor 1) (LOX-1) [Contains: Oxidized low-density lipoprotein receptor 1, soluble form].

RABE1_HUMAN
θ value	6.88961 (rank : 98)	NC score	0.040953 (rank : 16)
Query Neighborhood Hits	114	Target Neighborhood Hits	1104	Shared Neighborhood Hits	67
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

SL9A1_HUMAN
θ value	6.88961 (rank : 99)	NC score	0.008144 (rank : 101)
Query Neighborhood Hits	114	Target Neighborhood Hits	38	Shared Neighborhood Hits	4
SwissProt Accessions	P19634	Gene names	SLC9A1, APNH1, NHE1
Domain Architecture
Description	Sodium/hydrogen exchanger 1 (Na(+)/H(+) exchanger 1) (NHE-1) (Solute carrier family 9 member 1) (Na(+)/H(+) antiporter, amiloride- sensitive) (APNH).

SMG1_HUMAN
θ value	6.88961 (rank : 100)	NC score	0.013345 (rank : 93)
Query Neighborhood Hits	114	Target Neighborhood Hits	231	Shared Neighborhood Hits	25
SwissProt Accessions	Q96Q15, O43305, Q13284, Q8NFX2, Q96QV0, Q96RW3	Gene names	SMG1, ATX, KIAA0421, LIP
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SMG1 (EC 2.7.11.1) (SMG-1) (hSMG-1) (Lambda/iota protein kinase C-interacting protein) (Lambda-interacting protein) (61E3.4).

SNX23_HUMAN
θ value	6.88961 (rank : 101)	NC score	0.021982 (rank : 70)
Query Neighborhood Hits	114	Target Neighborhood Hits	944	Shared Neighborhood Hits	61
SwissProt Accessions	Q96L93, Q5HYC0, Q5HYK1, Q5JWW3, Q5TFK5, Q86VL9, Q86YS5, Q8IYU0, Q9BQJ8, Q9BQM0, Q9BQM1, Q9BQM5, Q9H5U0, Q9HCI2, Q9NXN9	Gene names	C20orf23, KIAA1590, SNX23
Domain Architecture
Description	Kinesin-like motor protein C20orf23 (Sorting nexin-23).

AOF1_MOUSE
θ value	8.99809 (rank : 102)	NC score	0.005236 (rank : 106)
Query Neighborhood Hits	114	Target Neighborhood Hits	51	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CIG3, Q8C5C4, Q8CEC1	Gene names	Aof1
Domain Architecture	No domain graphic available
Description	Flavin-containing amine oxidase domain-containing protein 1 (EC 1.-.-.-).

CALD1_HUMAN
θ value	8.99809 (rank : 103)	NC score	0.027900 (rank : 52)
Query Neighborhood Hits	114	Target Neighborhood Hits	959	Shared Neighborhood Hits	60
SwissProt Accessions	Q05682, Q13978, Q13979, Q14741, Q14742	Gene names	CALD1, CAD, CDM
Domain Architecture
Description	Caldesmon (CDM).

CT2NL_HUMAN
θ value	8.99809 (rank : 104)	NC score	0.027690 (rank : 54)
Query Neighborhood Hits	114	Target Neighborhood Hits	1059	Shared Neighborhood Hits	68
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

CTGE5_HUMAN
θ value	8.99809 (rank : 105)	NC score	0.026655 (rank : 60)
Query Neighborhood Hits	114	Target Neighborhood Hits	800	Shared Neighborhood Hits	66
SwissProt Accessions	O15320, O00169, Q6P2R8, Q8IX92, Q8IX93	Gene names	CTAGE5, MEA11, MEA6, MGEA11, MGEA6
Domain Architecture
Description	Cutaneous T-cell lymphoma-associated antigen 5 (cTAGE-5 protein) (cTAGE family member 5) (Meningioma-expressed antigen 6/11).

DLG5_HUMAN
θ value	8.99809 (rank : 106)	NC score	0.031124 (rank : 41)
Query Neighborhood Hits	114	Target Neighborhood Hits	1088	Shared Neighborhood Hits	65
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

DZIP1_MOUSE
θ value	8.99809 (rank : 107)	NC score	0.019203 (rank : 82)
Query Neighborhood Hits	114	Target Neighborhood Hits	530	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BMD2, Q6ZQ10, Q9CRK5	Gene names	Dzip1, Kiaa0996
Domain Architecture	No domain graphic available
Description	Zinc finger protein DZIP1 (DAZ-interacting protein 1 homolog).

IGB1B_MOUSE
θ value	8.99809 (rank : 108)	NC score	0.007783 (rank : 103)
Query Neighborhood Hits	114	Target Neighborhood Hits	37	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QZ29	Gene names	Igbp1b
Domain Architecture
Description	Immunoglobulin-binding protein 1b (CD79a-binding protein 1b) (Alpha 4- b protein) (Alpha4-b).

KKCC1_MOUSE
θ value	8.99809 (rank : 109)	NC score	0.000454 (rank : 114)
Query Neighborhood Hits	114	Target Neighborhood Hits	866	Shared Neighborhood Hits	9
SwissProt Accessions	Q8VBY2, Q9R054	Gene names	Camkk1, Camkk
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase kinase 1 (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase alpha) (CaM-kinase kinase alpha) (CaM-KK alpha) (CaMKK alpha) (CaMKK 1) (CaM-kinase IV kinase).

MACF1_MOUSE
θ value	8.99809 (rank : 110)	NC score	0.025844 (rank : 63)
Query Neighborhood Hits	114	Target Neighborhood Hits	1313	Shared Neighborhood Hits	66
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

MYH3_HUMAN
θ value	8.99809 (rank : 111)	NC score	0.026606 (rank : 61)
Query Neighborhood Hits	114	Target Neighborhood Hits	1660	Shared Neighborhood Hits	72
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

PANK2_HUMAN
θ value	8.99809 (rank : 112)	NC score	0.004965 (rank : 109)
Query Neighborhood Hits	114	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BZ23, Q5T7I2, Q8N7Q4, Q8TCR5, Q9BYW5, Q9HAF2	Gene names	PANK2, C20orf48
Domain Architecture
Description	Pantothenate kinase 2, mitochondrial precursor (EC 2.7.1.33) (Pantothenic acid kinase 2) (hPANK2).

RBCC1_MOUSE
θ value	8.99809 (rank : 113)	NC score	0.028435 (rank : 49)
Query Neighborhood Hits	114	Target Neighborhood Hits	1048	Shared Neighborhood Hits	62
SwissProt Accessions	Q9ESK9, Q3TXX2, Q61384, Q8BRY9, Q9JK14	Gene names	Rb1cc1, Cc1, Kiaa0203
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1 (Coiled-coil-forming protein 1) (LaXp180 protein).

RBMS1_HUMAN
θ value	8.99809 (rank : 114)	NC score	0.005321 (rank : 105)
Query Neighborhood Hits	114	Target Neighborhood Hits	190	Shared Neighborhood Hits	3
SwissProt Accessions	P29558, Q15433, Q8WV20	Gene names	RBMS1, MSSP, MSSP1, SCR2
Domain Architecture
Description	RNA-binding motif, single-stranded-interacting protein 1 (Single- stranded DNA-binding protein MSSP-1) (Suppressor of CDC2 with RNA- binding motif 2).

Hits sorted by NC score

ITPR3_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 5)
Query Neighborhood Hits	114	Target Neighborhood Hits	114	Shared Neighborhood Hits	114
SwissProt Accessions	Q14573, Q14649	Gene names	ITPR3
Domain Architecture
Description	Inositol 1,4,5-trisphosphate receptor type 3 (Type 3 inositol 1,4,5- trisphosphate receptor) (Type 3 InsP3 receptor) (IP3 receptor isoform 3) (InsP3R3).

ITPR3_MOUSE
NC score	0.997177 (rank : 2)	θ value	0 (rank : 6)
Query Neighborhood Hits	114	Target Neighborhood Hits	105	Shared Neighborhood Hits	75
SwissProt Accessions	P70227, Q5DWM4, Q8CED5, Q91Z08	Gene names	Itpr3
Domain Architecture	No domain graphic available
Description	Inositol 1,4,5-trisphosphate receptor type 3 (Type 3 inositol 1,4,5- trisphosphate receptor) (Type 3 InsP3 receptor) (IP3 receptor isoform 3) (InsP3R3).

ITPR2_MOUSE
NC score	0.991022 (rank : 3)	θ value	0 (rank : 4)
Query Neighborhood Hits	114	Target Neighborhood Hits	69	Shared Neighborhood Hits	22
SwissProt Accessions	Q9Z329, P70226, Q5DWM3, Q5DWM5, Q61744, Q8R3B0	Gene names	Itpr2, Itpr5
Domain Architecture	No domain graphic available
Description	Inositol 1,4,5-trisphosphate receptor type 2 (Type 2 inositol 1,4,5- trisphosphate receptor) (Type 2 InsP3 receptor) (IP3 receptor isoform 2) (InsP3R2) (Inositol 1,4,5-trisphosphate type V receptor).

ITPR2_HUMAN
NC score	0.990631 (rank : 4)	θ value	0 (rank : 3)
Query Neighborhood Hits	114	Target Neighborhood Hits	74	Shared Neighborhood Hits	19
SwissProt Accessions	Q14571, O94773	Gene names	ITPR2
Domain Architecture
Description	Inositol 1,4,5-trisphosphate receptor type 2 (Type 2 inositol 1,4,5- trisphosphate receptor) (Type 2 InsP3 receptor) (IP3 receptor isoform 2) (InsP3R2).

ITPR1_HUMAN
NC score	0.989276 (rank : 5)	θ value	0 (rank : 1)
Query Neighborhood Hits	114	Target Neighborhood Hits	90	Shared Neighborhood Hits	22
SwissProt Accessions	Q14643, Q14660, Q99897	Gene names	ITPR1, INSP3R1
Domain Architecture
Description	Inositol 1,4,5-trisphosphate receptor type 1 (Type 1 inositol 1,4,5- trisphosphate receptor) (Type 1 InsP3 receptor) (IP3 receptor isoform 1) (InsP3R1) (IP3R).

ITPR1_MOUSE
NC score	0.988722 (rank : 6)	θ value	0 (rank : 2)
Query Neighborhood Hits	114	Target Neighborhood Hits	99	Shared Neighborhood Hits	22
SwissProt Accessions	P11881, P20943, Q99LG5	Gene names	Itpr1, Insp3r, Pcd6, Pcp1
Domain Architecture
Description	Inositol 1,4,5-trisphosphate receptor type 1 (Type 1 inositol 1,4,5- trisphosphate receptor) (Type 1 InsP3 receptor) (IP3 receptor isoform 1) (InsP3R1) (Inositol 1,4,5-trisphosphate-binding protein P400) (Purkinje cell protein 1) (Protein PCD-6).

RYR3_HUMAN
NC score	0.542713 (rank : 7)	θ value	1.33217e-27 (rank : 9)
Query Neighborhood Hits	114	Target Neighborhood Hits	134	Shared Neighborhood Hits	13
SwissProt Accessions	Q15413, O15175, Q15412	Gene names	RYR3, HBRR
Domain Architecture
Description	Ryanodine receptor 3 (Brain-type ryanodine receptor) (RyR3) (RYR-3) (Brain ryanodine receptor-calcium release channel).

RYR1_HUMAN
NC score	0.536980 (rank : 8)	θ value	4.57862e-28 (rank : 8)
Query Neighborhood Hits	114	Target Neighborhood Hits	303	Shared Neighborhood Hits	18
SwissProt Accessions	P21817, Q16314, Q16368, Q9NPK1, Q9P1U4	Gene names	RYR1, RYDR
Domain Architecture
Description	Ryanodine receptor 1 (Skeletal muscle-type ryanodine receptor) (RyR1) (RYR-1) (Skeletal muscle calcium release channel).

RYR2_HUMAN
NC score	0.532386 (rank : 9)	θ value	3.50572e-28 (rank : 7)
Query Neighborhood Hits	114	Target Neighborhood Hits	175	Shared Neighborhood Hits	15
SwissProt Accessions	Q92736, Q15411, Q546N8	Gene names	RYR2
Domain Architecture
Description	Ryanodine receptor 2 (Cardiac muscle-type ryanodine receptor) (RyR2) (RYR-2) (Cardiac muscle ryanodine receptor-calcium release channel) (hRYR-2).

OPTN_MOUSE
NC score	0.053057 (rank : 10)	θ value	0.0148317 (rank : 10)
Query Neighborhood Hits	114	Target Neighborhood Hits	1120	Shared Neighborhood Hits	68
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

CJ118_MOUSE
NC score	0.050991 (rank : 11)	θ value	1.81305 (rank : 39)
Query Neighborhood Hits	114	Target Neighborhood Hits	1132	Shared Neighborhood Hits	71
SwissProt Accessions	Q8C9S4, Q6P3D6, Q8CJC0	Gene names	Otg1
Domain Architecture	No domain graphic available
Description	Protein C10orf118 homolog (Oocyte-testis gene 1 protein).

EP15_HUMAN
NC score	0.047385 (rank : 12)	θ value	0.813845 (rank : 26)
Query Neighborhood Hits	114	Target Neighborhood Hits	1021	Shared Neighborhood Hits	69
SwissProt Accessions	P42566	Gene names	EPS15, AF1P
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

PAIP1_MOUSE
NC score	0.047374 (rank : 13)	θ value	0.365318 (rank : 19)
Query Neighborhood Hits	114	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	Q8VE62, Q9WUC9	Gene names	Paip1
Domain Architecture
Description	Polyadenylate-binding protein-interacting protein 1 (Poly(A)-binding protein-interacting protein 1) (PABP-interacting protein 1) (PAIP-1).

GOGA4_HUMAN
NC score	0.046815 (rank : 14)	θ value	0.0961366 (rank : 12)
Query Neighborhood Hits	114	Target Neighborhood Hits	2034	Shared Neighborhood Hits	75
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

LRC45_MOUSE
NC score	0.044214 (rank : 15)	θ value	1.38821 (rank : 37)
Query Neighborhood Hits	114	Target Neighborhood Hits	959	Shared Neighborhood Hits	67
SwissProt Accessions	Q8CIM1, Q3U5Z2	Gene names	Lrrc45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

RABE1_HUMAN
NC score	0.040953 (rank : 16)	θ value	6.88961 (rank : 98)
Query Neighborhood Hits	114	Target Neighborhood Hits	1104	Shared Neighborhood Hits	67
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

GOGB1_HUMAN
NC score	0.040097 (rank : 17)	θ value	0.365318 (rank : 17)
Query Neighborhood Hits	114	Target Neighborhood Hits	2297	Shared Neighborhood Hits	77
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

RBP24_HUMAN
NC score	0.039116 (rank : 18)	θ value	0.21417 (rank : 15)
Query Neighborhood Hits	114	Target Neighborhood Hits	1559	Shared Neighborhood Hits	68
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

GCC2_HUMAN
NC score	0.039053 (rank : 19)	θ value	0.21417 (rank : 14)
Query Neighborhood Hits	114	Target Neighborhood Hits	1558	Shared Neighborhood Hits	68
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

CEP57_MOUSE
NC score	0.038337 (rank : 20)	θ value	0.365318 (rank : 16)
Query Neighborhood Hits	114	Target Neighborhood Hits	580	Shared Neighborhood Hits	58
SwissProt Accessions	Q8CEE0, Q6ZQJ3, Q7TN18, Q80X65, Q810F2, Q9D4J4, Q9D5S4, Q9D5W5	Gene names	Cep57, Kiaa0092, Tsp57
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 57 kDa (Cep57 protein) (Testis-specific protein 57) (Translokin).

CE152_HUMAN
NC score	0.037532 (rank : 21)	θ value	4.03905 (rank : 60)
Query Neighborhood Hits	114	Target Neighborhood Hits	976	Shared Neighborhood Hits	65
SwissProt Accessions	O94986, Q6NTA0	Gene names	CEP152, KIAA0912
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 152 kDa (Cep152 protein).

LRC45_HUMAN
NC score	0.037053 (rank : 22)	θ value	2.36792 (rank : 47)
Query Neighborhood Hits	114	Target Neighborhood Hits	933	Shared Neighborhood Hits	64
SwissProt Accessions	Q96CN5	Gene names	LRRC45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

PAIP1_HUMAN
NC score	0.037047 (rank : 23)	θ value	1.38821 (rank : 38)
Query Neighborhood Hits	114	Target Neighborhood Hits	76	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H074, O60455, Q96B61, Q9BS63	Gene names	PAIP1
Domain Architecture
Description	Polyadenylate-binding protein-interacting protein 1 (Poly(A)-binding protein-interacting protein 1) (PABP-interacting protein 1) (PAIP-1).

CP250_MOUSE
NC score	0.036716 (rank : 24)	θ value	1.06291 (rank : 33)
Query Neighborhood Hits	114	Target Neighborhood Hits	1583	Shared Neighborhood Hits	73
SwissProt Accessions	Q60952, Q2I8G3, Q3UTR4, Q6PFF6, Q8BLC6	Gene names	Cep250, Cep2, Inmp
Domain Architecture	No domain graphic available
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Intranuclear matrix protein).

NUF2_HUMAN
NC score	0.036304 (rank : 25)	θ value	6.88961 (rank : 96)
Query Neighborhood Hits	114	Target Neighborhood Hits	661	Shared Neighborhood Hits	61
SwissProt Accessions	Q9BZD4, Q8WU69, Q96HJ4, Q96Q78	Gene names	CDCA1, NUF2, NUF2R
Domain Architecture	No domain graphic available
Description	Kinetochore protein Nuf2 (hNuf2) (hNuf2R) (hsNuf2) (Cell division cycle-associated protein 1).

CN145_HUMAN
NC score	0.035716 (rank : 26)	θ value	1.81305 (rank : 40)
Query Neighborhood Hits	114	Target Neighborhood Hits	1196	Shared Neighborhood Hits	69
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

TPR_HUMAN
NC score	0.035437 (rank : 27)	θ value	0.47712 (rank : 23)
Query Neighborhood Hits	114	Target Neighborhood Hits	1921	Shared Neighborhood Hits	67
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

CENPF_HUMAN
NC score	0.035378 (rank : 28)	θ value	0.47712 (rank : 21)
Query Neighborhood Hits	114	Target Neighborhood Hits	1932	Shared Neighborhood Hits	72
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

CN145_MOUSE
NC score	0.034519 (rank : 29)	θ value	4.03905 (rank : 62)
Query Neighborhood Hits	114	Target Neighborhood Hits	916	Shared Neighborhood Hits	62
SwissProt Accessions	Q8BI22	Gene names
Domain Architecture	No domain graphic available
Description	Protein C14orf145 homolog.

MYH14_MOUSE
NC score	0.034389 (rank : 30)	θ value	1.06291 (rank : 34)
Query Neighborhood Hits	114	Target Neighborhood Hits	1225	Shared Neighborhood Hits	71
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

CJ068_HUMAN
NC score	0.033634 (rank : 31)	θ value	4.03905 (rank : 61)
Query Neighborhood Hits	114	Target Neighborhood Hits	316	Shared Neighborhood Hits	36
SwissProt Accessions	Q9H943, Q8N7T7	Gene names	C10orf68
Domain Architecture	No domain graphic available
Description	Protein C10orf68.

HOOK3_MOUSE
NC score	0.033429 (rank : 32)	θ value	3.0926 (rank : 54)
Query Neighborhood Hits	114	Target Neighborhood Hits	1007	Shared Neighborhood Hits	64
SwissProt Accessions	Q8BUK6, Q8BV48, Q8BW57, Q8BY41	Gene names	Hook3
Domain Architecture
Description	Hook homolog 3.

MD1L1_HUMAN
NC score	0.033225 (rank : 33)	θ value	6.88961 (rank : 92)
Query Neighborhood Hits	114	Target Neighborhood Hits	893	Shared Neighborhood Hits	63
SwissProt Accessions	Q9Y6D9, Q13312, Q75MI0, Q86UM4, Q9UNH0	Gene names	MAD1L1, MAD1, TXBP181
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1) (Mitotic checkpoint MAD1 protein-homolog) (HsMAD1) (hMAD1) (Tax-binding protein 181).

ANR26_MOUSE
NC score	0.033213 (rank : 34)	θ value	0.813845 (rank : 25)
Query Neighborhood Hits	114	Target Neighborhood Hits	1554	Shared Neighborhood Hits	72
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

GP158_MOUSE
NC score	0.032764 (rank : 35)	θ value	0.813845 (rank : 27)
Query Neighborhood Hits	114	Target Neighborhood Hits	82	Shared Neighborhood Hits	7
SwissProt Accessions	Q8C419, Q8CHB0	Gene names	Gpr158, Kiaa1136
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 158 precursor.

PCNT_HUMAN
NC score	0.032589 (rank : 36)	θ value	3.0926 (rank : 56)
Query Neighborhood Hits	114	Target Neighborhood Hits	1551	Shared Neighborhood Hits	69
SwissProt Accessions	O95613, O43152, Q7Z7C9	Gene names	PCNT, KIAA0402, PCNT2
Domain Architecture
Description	Pericentrin (Pericentrin B) (Kendrin).

MYH11_MOUSE
NC score	0.032552 (rank : 37)	θ value	0.365318 (rank : 18)
Query Neighborhood Hits	114	Target Neighborhood Hits	1777	Shared Neighborhood Hits	77
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

HOOK3_HUMAN
NC score	0.032429 (rank : 38)	θ value	4.03905 (rank : 65)
Query Neighborhood Hits	114	Target Neighborhood Hits	1070	Shared Neighborhood Hits	63
SwissProt Accessions	Q86VS8, Q8NBH0, Q9BY13	Gene names	HOOK3
Domain Architecture
Description	Hook homolog 3 (hHK3).

CT2NL_MOUSE
NC score	0.032326 (rank : 39)	θ value	3.0926 (rank : 51)
Query Neighborhood Hits	114	Target Neighborhood Hits	902	Shared Neighborhood Hits	67
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

AKAP9_HUMAN
NC score	0.031541 (rank : 40)	θ value	5.27518 (rank : 76)
Query Neighborhood Hits	114	Target Neighborhood Hits	1710	Shared Neighborhood Hits	69
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

DLG5_HUMAN
NC score	0.031124 (rank : 41)	θ value	8.99809 (rank : 106)
Query Neighborhood Hits	114	Target Neighborhood Hits	1088	Shared Neighborhood Hits	65
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

CE290_HUMAN
NC score	0.031023 (rank : 42)	θ value	5.27518 (rank : 77)
Query Neighborhood Hits	114	Target Neighborhood Hits	1553	Shared Neighborhood Hits	70
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

DMD_HUMAN
NC score	0.030456 (rank : 43)	θ value	6.88961 (rank : 84)
Query Neighborhood Hits	114	Target Neighborhood Hits	1135	Shared Neighborhood Hits	71
SwissProt Accessions	P11532, Q02295, Q14169, Q14170, Q5JYU0, Q7KZ48	Gene names	DMD
Domain Architecture
Description	Dystrophin.

GBGT2_HUMAN
NC score	0.030111 (rank : 44)	θ value	2.36792 (rank : 45)
Query Neighborhood Hits	114	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	O14610	Gene names	GNGT2, GNG8, GNG9, GNGT8
Domain Architecture
Description	Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-T2 subunit precursor (G gamma-C) (G-gamma-8) (G-gamma 9).

RUFY1_HUMAN
NC score	0.029969 (rank : 45)	θ value	1.81305 (rank : 42)
Query Neighborhood Hits	114	Target Neighborhood Hits	848	Shared Neighborhood Hits	63
SwissProt Accessions	Q96T51, Q59FF3, Q71S93, Q9H6I3	Gene names	RUFY1, RABIP4, ZFYVE12
Domain Architecture
Description	RUN and FYVE domain-containing protein 1 (FYVE-finger protein EIP1) (Zinc finger FYVE domain-containing protein 12) (La-binding protein 1) (Rab4-interacting protein).

GCP6_HUMAN
NC score	0.029958 (rank : 46)	θ value	2.36792 (rank : 46)
Query Neighborhood Hits	114	Target Neighborhood Hits	295	Shared Neighborhood Hits	27
SwissProt Accessions	Q96RT7, Q5JZ80, Q6PJ40, Q86YE9, Q9BY91, Q9UGX3, Q9UGX4	Gene names	TUBGCP6, GCP6, KIAA1669
Domain Architecture
Description	Gamma-tubulin complex component 6 (GCP-6).

APHC_HUMAN
NC score	0.029786 (rank : 47)	θ value	4.03905 (rank : 59)
Query Neighborhood Hits	114	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NUN7	Gene names	PHCA, APHC
Domain Architecture
Description	Alkaline phytoceramidase (EC 3.5.1.-) (aPHC) (Alkaline ceramidase) (Alkaline dihydroceramidase SB89).

MYH10_MOUSE
NC score	0.029027 (rank : 48)	θ value	4.03905 (rank : 68)
Query Neighborhood Hits	114	Target Neighborhood Hits	1612	Shared Neighborhood Hits	69
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

RBCC1_MOUSE
NC score	0.028435 (rank : 49)	θ value	8.99809 (rank : 113)
Query Neighborhood Hits	114	Target Neighborhood Hits	1048	Shared Neighborhood Hits	62
SwissProt Accessions	Q9ESK9, Q3TXX2, Q61384, Q8BRY9, Q9JK14	Gene names	Rb1cc1, Cc1, Kiaa0203
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1 (Coiled-coil-forming protein 1) (LaXp180 protein).

MYH11_HUMAN
NC score	0.028417 (rank : 50)	θ value	4.03905 (rank : 69)
Query Neighborhood Hits	114	Target Neighborhood Hits	1806	Shared Neighborhood Hits	75
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYH9_MOUSE
NC score	0.027990 (rank : 51)	θ value	0.813845 (rank : 28)
Query Neighborhood Hits	114	Target Neighborhood Hits	1829	Shared Neighborhood Hits	73
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

CALD1_HUMAN
NC score	0.027900 (rank : 52)	θ value	8.99809 (rank : 103)
Query Neighborhood Hits	114	Target Neighborhood Hits	959	Shared Neighborhood Hits	60
SwissProt Accessions	Q05682, Q13978, Q13979, Q14741, Q14742	Gene names	CALD1, CAD, CDM
Domain Architecture
Description	Caldesmon (CDM).

LUZP1_MOUSE
NC score	0.027801 (rank : 53)	θ value	6.88961 (rank : 91)
Query Neighborhood Hits	114	Target Neighborhood Hits	940	Shared Neighborhood Hits	65
SwissProt Accessions	Q8R4U7, Q3UV18, Q7TS71, Q8BQW1, Q99NG3, Q9CSL6	Gene names	Luzp1, Luzp
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1 (Leucine zipper motif-containing protein).

CT2NL_HUMAN
NC score	0.027690 (rank : 54)	θ value	8.99809 (rank : 104)
Query Neighborhood Hits	114	Target Neighborhood Hits	1059	Shared Neighborhood Hits	68
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

MYH6_MOUSE
NC score	0.027246 (rank : 55)	θ value	6.88961 (rank : 94)
Query Neighborhood Hits	114	Target Neighborhood Hits	1501	Shared Neighborhood Hits	72
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

RRP44_HUMAN
NC score	0.027200 (rank : 56)	θ value	3.0926 (rank : 57)
Query Neighborhood Hits	114	Target Neighborhood Hits	35	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Y2L1, Q5W0P7, Q5W0P8, Q658Z7, Q7Z481, Q8WWI2, Q9UG36	Gene names	DIS3, KIAA1008, RRP44
Domain Architecture
Description	Exosome complex exonuclease RRP44 (EC 3.1.13.-) (Ribosomal RNA- processing protein 44) (DIS3 protein homolog).

MY18A_MOUSE
NC score	0.027143 (rank : 57)	θ value	4.03905 (rank : 67)
Query Neighborhood Hits	114	Target Neighborhood Hits	1989	Shared Neighborhood Hits	71
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

COVA1_HUMAN
NC score	0.026961 (rank : 58)	θ value	6.88961 (rank : 82)
Query Neighborhood Hits	114	Target Neighborhood Hits	416	Shared Neighborhood Hits	50
SwissProt Accessions	Q16206, Q5VTJ1, Q5VTJ2, Q8WUX0, Q9NTP6, Q9UH82	Gene names	COVA1
Domain Architecture
Description	Tumor-associated hydroquinone oxidase (tNOX) (Cytosolic ovarian carcinoma antigen 1) (APK1 antigen) [Includes: Hydroquinone [NADH] oxidase (EC 1.-.-.-); Protein disulfide-thiol oxidoreductase (EC 1.-.-.-)].

MY18A_HUMAN
NC score	0.026899 (rank : 59)	θ value	4.03905 (rank : 66)
Query Neighborhood Hits	114	Target Neighborhood Hits	1929	Shared Neighborhood Hits	69
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

CTGE5_HUMAN
NC score	0.026655 (rank : 60)	θ value	8.99809 (rank : 105)
Query Neighborhood Hits	114	Target Neighborhood Hits	800	Shared Neighborhood Hits	66
SwissProt Accessions	O15320, O00169, Q6P2R8, Q8IX92, Q8IX93	Gene names	CTAGE5, MEA11, MEA6, MGEA11, MGEA6
Domain Architecture
Description	Cutaneous T-cell lymphoma-associated antigen 5 (cTAGE-5 protein) (cTAGE family member 5) (Meningioma-expressed antigen 6/11).

MYH3_HUMAN
NC score	0.026606 (rank : 61)	θ value	8.99809 (rank : 111)
Query Neighborhood Hits	114	Target Neighborhood Hits	1660	Shared Neighborhood Hits	72
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

KINH_HUMAN
NC score	0.026460 (rank : 62)	θ value	0.47712 (rank : 22)
Query Neighborhood Hits	114	Target Neighborhood Hits	1231	Shared Neighborhood Hits	69
SwissProt Accessions	P33176, Q5VZ85	Gene names	KIF5B, KNS, KNS1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

MACF1_MOUSE
NC score	0.025844 (rank : 63)	θ value	8.99809 (rank : 110)
Query Neighborhood Hits	114	Target Neighborhood Hits	1313	Shared Neighborhood Hits	66
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

RAI14_MOUSE
NC score	0.025820 (rank : 64)	θ value	4.03905 (rank : 72)
Query Neighborhood Hits	114	Target Neighborhood Hits	1505	Shared Neighborhood Hits	69
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

KINH_MOUSE
NC score	0.025388 (rank : 65)	θ value	1.81305 (rank : 41)
Query Neighborhood Hits	114	Target Neighborhood Hits	1082	Shared Neighborhood Hits	67
SwissProt Accessions	Q61768, O08711, Q61580	Gene names	Kif5b, Khcs, Kns1
Domain Architecture
Description	Kinesin heavy chain (Ubiquitous kinesin heavy chain) (UKHC).

ENAH_HUMAN
NC score	0.025073 (rank : 66)	θ value	1.38821 (rank : 36)
Query Neighborhood Hits	114	Target Neighborhood Hits	784	Shared Neighborhood Hits	55
SwissProt Accessions	Q8N8S7, Q502W5, Q5T5M7, Q5VTQ9, Q5VTR0, Q9NVF3, Q9UFB8	Gene names	ENAH, MENA
Domain Architecture
Description	Protein enabled homolog.

GP158_HUMAN
NC score	0.024214 (rank : 67)	θ value	3.0926 (rank : 53)
Query Neighborhood Hits	114	Target Neighborhood Hits	221	Shared Neighborhood Hits	9
SwissProt Accessions	Q5T848, Q6QR81, Q9ULT3	Gene names	GPR158, KIAA1136
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 158 precursor.

OLR1_MOUSE
NC score	0.024196 (rank : 68)	θ value	6.88961 (rank : 97)
Query Neighborhood Hits	114	Target Neighborhood Hits	596	Shared Neighborhood Hits	49
SwissProt Accessions	Q9EQ09	Gene names	Olr1, Lox1
Domain Architecture	No domain graphic available
Description	Oxidized low-density lipoprotein receptor 1 (Ox-LDL receptor 1) (Lectin-type oxidized LDL receptor 1) (Lectin-like oxidized LDL receptor 1) (Lectin-like oxLDL receptor 1) (LOX-1) [Contains: Oxidized low-density lipoprotein receptor 1, soluble form].

MYO5B_HUMAN
NC score	0.022736 (rank : 69)	θ value	4.03905 (rank : 70)
Query Neighborhood Hits	114	Target Neighborhood Hits	911	Shared Neighborhood Hits	62
SwissProt Accessions	Q9ULV0	Gene names	MYO5B, KIAA1119
Domain Architecture
Description	Myosin-5B (Myosin Vb).

SNX23_HUMAN
NC score	0.021982 (rank : 70)	θ value	6.88961 (rank : 101)
Query Neighborhood Hits	114	Target Neighborhood Hits	944	Shared Neighborhood Hits	61
SwissProt Accessions	Q96L93, Q5HYC0, Q5HYK1, Q5JWW3, Q5TFK5, Q86VL9, Q86YS5, Q8IYU0, Q9BQJ8, Q9BQM0, Q9BQM1, Q9BQM5, Q9H5U0, Q9HCI2, Q9NXN9	Gene names	C20orf23, KIAA1590, SNX23
Domain Architecture
Description	Kinesin-like motor protein C20orf23 (Sorting nexin-23).

ROCK1_MOUSE
NC score	0.021875 (rank : 71)	θ value	0.365318 (rank : 20)
Query Neighborhood Hits	114	Target Neighborhood Hits	2126	Shared Neighborhood Hits	73
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

VIME_HUMAN
NC score	0.020795 (rank : 72)	θ value	0.47712 (rank : 24)
Query Neighborhood Hits	114	Target Neighborhood Hits	706	Shared Neighborhood Hits	59
SwissProt Accessions	P08670, Q15867, Q15868, Q15869, Q6LER9, Q8N850, Q96ML2, Q9NTM3	Gene names	VIM
Domain Architecture
Description	Vimentin.

OXRP_HUMAN
NC score	0.020748 (rank : 73)	θ value	0.813845 (rank : 29)
Query Neighborhood Hits	114	Target Neighborhood Hits	544	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

TTLL5_MOUSE
NC score	0.020606 (rank : 74)	θ value	3.0926 (rank : 58)
Query Neighborhood Hits	114	Target Neighborhood Hits	150	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CHB8	Gene names	Ttll5, Kiaa0998
Domain Architecture	No domain graphic available
Description	Tubulin--tyrosine ligase-like protein 5.

INT2_MOUSE
NC score	0.020409 (rank : 75)	θ value	3.0926 (rank : 55)
Query Neighborhood Hits	114	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q80UK8, Q5SXZ5, Q5SXZ6, Q6PCY7, Q6ZPU6, Q8CB15, Q9CSE0	Gene names	Ints2, Kiaa1287
Domain Architecture	No domain graphic available
Description	Integrator complex subunit 2 (Int2).

WDHD1_HUMAN
NC score	0.020218 (rank : 76)	θ value	0.813845 (rank : 31)
Query Neighborhood Hits	114	Target Neighborhood Hits	342	Shared Neighborhood Hits	6
SwissProt Accessions	O75717	Gene names	WDHD1, AND1
Domain Architecture
Description	WD repeat and HMG-box DNA-binding protein 1 (Acidic nucleoplasmic DNA- binding protein 1) (And-1).

CF010_HUMAN
NC score	0.020078 (rank : 77)	θ value	3.0926 (rank : 50)
Query Neighborhood Hits	114	Target Neighborhood Hits	329	Shared Neighborhood Hits	17
SwissProt Accessions	Q5SRN2, Q5SPI9, Q5SPJ0, Q5SPK9, Q5SPL0, Q5SRN3, Q5TG25, Q5TG26, Q8N4B6	Gene names	C6orf10
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf10.

NPAL3_MOUSE
NC score	0.019962 (rank : 78)	θ value	4.03905 (rank : 71)
Query Neighborhood Hits	114	Target Neighborhood Hits	17	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BGN5, Q6PG85, Q9D2Y2	Gene names	Npal3
Domain Architecture	No domain graphic available
Description	NIPA-like protein 3.

CTRO_HUMAN
NC score	0.019939 (rank : 79)	θ value	1.38821 (rank : 35)
Query Neighborhood Hits	114	Target Neighborhood Hits	2092	Shared Neighborhood Hits	71
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

ROCK1_HUMAN
NC score	0.019584 (rank : 80)	θ value	0.813845 (rank : 30)
Query Neighborhood Hits	114	Target Neighborhood Hits	2000	Shared Neighborhood Hits	69
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).

CTRO_MOUSE
NC score	0.019330 (rank : 81)	θ value	2.36792 (rank : 44)
Query Neighborhood Hits	114	Target Neighborhood Hits	2344	Shared Neighborhood Hits	72
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

DZIP1_MOUSE
NC score	0.019203 (rank : 82)	θ value	8.99809 (rank : 107)
Query Neighborhood Hits	114	Target Neighborhood Hits	530	Shared Neighborhood Hits	43
SwissProt Accessions	Q8BMD2, Q6ZQ10, Q9CRK5	Gene names	Dzip1, Kiaa0996
Domain Architecture	No domain graphic available
Description	Zinc finger protein DZIP1 (DAZ-interacting protein 1 homolog).

ERF1_HUMAN
NC score	0.018925 (rank : 83)	θ value	4.03905 (rank : 63)
Query Neighborhood Hits	114	Target Neighborhood Hits	13	Shared Neighborhood Hits	4
SwissProt Accessions	P62495, P46055, Q5M7Z7	Gene names	ETF1, ERF1, RF1
Domain Architecture	No domain graphic available
Description	Eukaryotic peptide chain release factor subunit 1 (eRF1) (Eukaryotic release factor 1) (TB3-1) (Cl1 protein).

ERF1_MOUSE
NC score	0.018925 (rank : 84)	θ value	4.03905 (rank : 64)
Query Neighborhood Hits	114	Target Neighborhood Hits	13	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BWY3, Q3TPZ6, Q91VH9	Gene names	Etf1
Domain Architecture	No domain graphic available
Description	Eukaryotic peptide chain release factor subunit 1 (eRF1) (Eukaryotic release factor 1).

LAMB1_HUMAN
NC score	0.018805 (rank : 85)	θ value	6.88961 (rank : 90)
Query Neighborhood Hits	114	Target Neighborhood Hits	1018	Shared Neighborhood Hits	59
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

SYTL4_MOUSE
NC score	0.017333 (rank : 86)	θ value	0.0563607 (rank : 11)
Query Neighborhood Hits	114	Target Neighborhood Hits	137	Shared Neighborhood Hits	4
SwissProt Accessions	Q9R0Q1, Q8R321, Q9R0Q0	Gene names	Sytl4, Slp4
Domain Architecture
Description	Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin).

CNGA1_MOUSE
NC score	0.016479 (rank : 87)	θ value	0.125558 (rank : 13)
Query Neighborhood Hits	114	Target Neighborhood Hits	198	Shared Neighborhood Hits	12
SwissProt Accessions	P29974, Q60776	Gene names	Cnga1, Cncg, Cncg1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

NPAL3_HUMAN
NC score	0.016357 (rank : 88)	θ value	6.88961 (rank : 95)
Query Neighborhood Hits	114	Target Neighborhood Hits	13	Shared Neighborhood Hits	4
SwissProt Accessions	Q6P499, Q6MZT9, Q9BVE6	Gene names	NPAL3
Domain Architecture	No domain graphic available
Description	NIPA-like protein 3.

KI21A_MOUSE
NC score	0.016125 (rank : 89)	θ value	6.88961 (rank : 89)
Query Neighborhood Hits	114	Target Neighborhood Hits	1317	Shared Neighborhood Hits	65
SwissProt Accessions	Q9QXL2, Q6P5H1, Q6ZPJ8, Q8BWZ9, Q8BXF1	Gene names	Kif21a, Kiaa1708
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A.

CTR9_HUMAN
NC score	0.015789 (rank : 90)	θ value	2.36792 (rank : 43)
Query Neighborhood Hits	114	Target Neighborhood Hits	383	Shared Neighborhood Hits	24
SwissProt Accessions	Q6PD62, Q15015	Gene names	CTR9, KIAA0155, SH2BP1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1).

CBX4_HUMAN
NC score	0.014916 (rank : 91)	θ value	1.06291 (rank : 32)
Query Neighborhood Hits	114	Target Neighborhood Hits	68	Shared Neighborhood Hits	2
SwissProt Accessions	O00257, Q96C04	Gene names	CBX4
Domain Architecture
Description	Chromobox protein homolog 4 (Polycomb 2 homolog) (Pc2) (hPc2).

DNMT1_HUMAN
NC score	0.014630 (rank : 92)	θ value	3.0926 (rank : 52)
Query Neighborhood Hits	114	Target Neighborhood Hits	401	Shared Neighborhood Hits	24
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

SMG1_HUMAN
NC score	0.013345 (rank : 93)	θ value	6.88961 (rank : 100)
Query Neighborhood Hits	114	Target Neighborhood Hits	231	Shared Neighborhood Hits	25
SwissProt Accessions	Q96Q15, O43305, Q13284, Q8NFX2, Q96QV0, Q96RW3	Gene names	SMG1, ATX, KIAA0421, LIP
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SMG1 (EC 2.7.11.1) (SMG-1) (hSMG-1) (Lambda/iota protein kinase C-interacting protein) (Lambda-interacting protein) (61E3.4).

TXD13_HUMAN
NC score	0.012882 (rank : 94)	θ value	4.03905 (rank : 74)
Query Neighborhood Hits	114	Target Neighborhood Hits	106	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H1E5, Q8N4P7, Q8NCC1, Q9UJA1, Q9ULQ8	Gene names	TXNDC13, KIAA1162
Domain Architecture
Description	Thioredoxin domain-containing protein 13 precursor.

BCAS4_HUMAN
NC score	0.012135 (rank : 95)	θ value	6.88961 (rank : 79)
Query Neighborhood Hits	114	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TDM0, Q5TD52, Q5TD53, Q5TD54, Q5U5K7, Q5XKE8, Q8IXI7, Q8NEZ6, Q8TDL9, Q9NX13, Q9Y511	Gene names	BCAS4
Domain Architecture	No domain graphic available
Description	Breast carcinoma amplified sequence 4.

SMCA2_HUMAN
NC score	0.011673 (rank : 96)	θ value	2.36792 (rank : 48)
Query Neighborhood Hits	114	Target Neighborhood Hits	503	Shared Neighborhood Hits	24
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

SYTL4_HUMAN
NC score	0.010921 (rank : 97)	θ value	4.03905 (rank : 73)
Query Neighborhood Hits	114	Target Neighborhood Hits	138	Shared Neighborhood Hits	5
SwissProt Accessions	Q96C24, Q5H9J3, Q5JPG8, Q8N9P4, Q9H4R0, Q9H4R1	Gene names	SYTL4
Domain Architecture
Description	Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin).

DHX16_HUMAN
NC score	0.010418 (rank : 98)	θ value	6.88961 (rank : 83)
Query Neighborhood Hits	114	Target Neighborhood Hits	356	Shared Neighborhood Hits	36
SwissProt Accessions	O60231, O60322, Q969X7, Q96QC1	Gene names	DHX16, DBP2, DDX16, KIAA0577
Domain Architecture
Description	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 (EC 3.6.1.-) (DEAH-box protein 16) (ATP-dependent RNA helicase #3).

CNGA1_HUMAN
NC score	0.009800 (rank : 99)	θ value	6.88961 (rank : 81)
Query Neighborhood Hits	114	Target Neighborhood Hits	149	Shared Neighborhood Hits	7
SwissProt Accessions	P29973, Q16279, Q16485	Gene names	CNGA1, CNCG, CNCG1
Domain Architecture
Description	cGMP-gated cation channel alpha 1 (CNG channel alpha 1) (CNG-1) (CNG1) (Cyclic nucleotide-gated channel alpha 1) (Cyclic nucleotide-gated channel, photoreceptor) (Cyclic nucleotide-gated cation channel 1) (Rod photoreceptor cGMP-gated channel subunit alpha).

CECR2_HUMAN
NC score	0.009645 (rank : 100)	θ value	6.88961 (rank : 80)
Query Neighborhood Hits	114	Target Neighborhood Hits	543	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BXF3, Q658Z4, Q96P58, Q9C0C3	Gene names	CECR2, KIAA1740
Domain Architecture
Description	Cat eye syndrome critical region protein 2.

SL9A1_HUMAN
NC score	0.008144 (rank : 101)	θ value	6.88961 (rank : 99)
Query Neighborhood Hits	114	Target Neighborhood Hits	38	Shared Neighborhood Hits	4
SwissProt Accessions	P19634	Gene names	SLC9A1, APNH1, NHE1
Domain Architecture
Description	Sodium/hydrogen exchanger 1 (Na(+)/H(+) exchanger 1) (NHE-1) (Solute carrier family 9 member 1) (Na(+)/H(+) antiporter, amiloride- sensitive) (APNH).

ABCAD_HUMAN
NC score	0.007887 (rank : 102)	θ value	3.0926 (rank : 49)
Query Neighborhood Hits	114	Target Neighborhood Hits	207	Shared Neighborhood Hits	6
SwissProt Accessions	Q86UQ4, Q6ZTT7, Q86WI2, Q8N248	Gene names	ABCA13
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 13.

IGB1B_MOUSE
NC score	0.007783 (rank : 103)	θ value	8.99809 (rank : 108)
Query Neighborhood Hits	114	Target Neighborhood Hits	37	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QZ29	Gene names	Igbp1b
Domain Architecture
Description	Immunoglobulin-binding protein 1b (CD79a-binding protein 1b) (Alpha 4- b protein) (Alpha4-b).

GTR2_HUMAN
NC score	0.006517 (rank : 104)	θ value	6.88961 (rank : 86)
Query Neighborhood Hits	114	Target Neighborhood Hits	40	Shared Neighborhood Hits	3
SwissProt Accessions	P11168	Gene names	SLC2A2, GLUT2
Domain Architecture
Description	Solute carrier family 2, facilitated glucose transporter member 2 (Glucose transporter type 2, liver).

RBMS1_HUMAN
NC score	0.005321 (rank : 105)	θ value	8.99809 (rank : 114)
Query Neighborhood Hits	114	Target Neighborhood Hits	190	Shared Neighborhood Hits	3
SwissProt Accessions	P29558, Q15433, Q8WV20	Gene names	RBMS1, MSSP, MSSP1, SCR2
Domain Architecture
Description	RNA-binding motif, single-stranded-interacting protein 1 (Single- stranded DNA-binding protein MSSP-1) (Suppressor of CDC2 with RNA- binding motif 2).

AOF1_MOUSE
NC score	0.005236 (rank : 106)	θ value	8.99809 (rank : 102)
Query Neighborhood Hits	114	Target Neighborhood Hits	51	Shared Neighborhood Hits	2
SwissProt Accessions	Q8CIG3, Q8C5C4, Q8CEC1	Gene names	Aof1
Domain Architecture	No domain graphic available
Description	Flavin-containing amine oxidase domain-containing protein 1 (EC 1.-.-.-).

MLL3_MOUSE
NC score	0.005115 (rank : 107)	θ value	6.88961 (rank : 93)
Query Neighborhood Hits	114	Target Neighborhood Hits	1399	Shared Neighborhood Hits	29
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

TNIK_HUMAN
NC score	0.005064 (rank : 108)	θ value	5.27518 (rank : 78)
Query Neighborhood Hits	114	Target Neighborhood Hits	1570	Shared Neighborhood Hits	56
SwissProt Accessions	Q9UKE5, O60298, Q8WUY7, Q9UKD8, Q9UKD9, Q9UKE0, Q9UKE1, Q9UKE2, Q9UKE3, Q9UKE4	Gene names	TNIK, KIAA0551
Domain Architecture
Description	TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1).

PANK2_HUMAN
NC score	0.004965 (rank : 109)	θ value	8.99809 (rank : 112)
Query Neighborhood Hits	114	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BZ23, Q5T7I2, Q8N7Q4, Q8TCR5, Q9BYW5, Q9HAF2	Gene names	PANK2, C20orf48
Domain Architecture
Description	Pantothenate kinase 2, mitochondrial precursor (EC 2.7.1.33) (Pantothenic acid kinase 2) (hPANK2).

KGP2_HUMAN
NC score	0.002976 (rank : 110)	θ value	6.88961 (rank : 88)
Query Neighborhood Hits	114	Target Neighborhood Hits	1023	Shared Neighborhood Hits	35
SwissProt Accessions	Q13237, O00125, O60916	Gene names	PRKG2, PRKGR2
Domain Architecture
Description	cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).

FRAS1_HUMAN
NC score	0.001576 (rank : 111)	θ value	6.88961 (rank : 85)
Query Neighborhood Hits	114	Target Neighborhood Hits	759	Shared Neighborhood Hits	5
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

HIPK1_HUMAN
NC score	0.000921 (rank : 112)	θ value	6.88961 (rank : 87)
Query Neighborhood Hits	114	Target Neighborhood Hits	843	Shared Neighborhood Hits	9
SwissProt Accessions	Q86Z02, O75125, Q8IYD7, Q8NDN5, Q8NEB6, Q8TBZ1	Gene names	HIPK1, KIAA0630
Domain Architecture
Description	Homeodomain-interacting protein kinase 1 (EC 2.7.11.1).

ZEP2_MOUSE
NC score	0.000760 (rank : 113)	θ value	4.03905 (rank : 75)
Query Neighborhood Hits	114	Target Neighborhood Hits	964	Shared Neighborhood Hits	9
SwissProt Accessions	Q3UHF7, O55140, Q3UVD4, Q3UVH5	Gene names	Hivep2, Mibp1
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 homolog (Myc intron-binding protein 1) (MIBP-1).

KKCC1_MOUSE
NC score	0.000454 (rank : 114)	θ value	8.99809 (rank : 109)
Query Neighborhood Hits	114	Target Neighborhood Hits	866	Shared Neighborhood Hits	9
SwissProt Accessions	Q8VBY2, Q9R054	Gene names	Camkk1, Camkk
Domain Architecture	No domain graphic available
Description	Calcium/calmodulin-dependent protein kinase kinase 1 (EC 2.7.11.17) (Calcium/calmodulin-dependent protein kinase kinase alpha) (CaM-kinase kinase alpha) (CaM-KK alpha) (CaMKK alpha) (CaMKK 1) (CaM-kinase IV kinase).