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Network neighborhood for query Sequence : ITPR2_MOUSE

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ITPR2_MOUSE
SwissProt Accessions	Q9Z329, P70226, Q5DWM3, Q5DWM5, Q61744, Q8R3B0	Gene names	Itpr2, Itpr5
Domain Architecture	No domain graphic available
Description	Inositol 1,4,5-trisphosphate receptor type 2 (Type 2 inositol 1,4,5- trisphosphate receptor) (Type 2 InsP3 receptor) (IP3 receptor isoform 2) (InsP3R2) (Inositol 1,4,5-trisphosphate type V receptor).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ITPR1_HUMAN
θ value	0 (rank : 1)	NC score	0.993545 (rank : 3)
Query Neighborhood Hits	69	Target Neighborhood Hits	90	Shared Neighborhood Hits	23
SwissProt Accessions	Q14643, Q14660, Q99897	Gene names	ITPR1, INSP3R1
Domain Architecture
Description	Inositol 1,4,5-trisphosphate receptor type 1 (Type 1 inositol 1,4,5- trisphosphate receptor) (Type 1 InsP3 receptor) (IP3 receptor isoform 1) (InsP3R1) (IP3R).

ITPR1_MOUSE
θ value	0 (rank : 2)	NC score	0.993088 (rank : 4)
Query Neighborhood Hits	69	Target Neighborhood Hits	99	Shared Neighborhood Hits	24
SwissProt Accessions	P11881, P20943, Q99LG5	Gene names	Itpr1, Insp3r, Pcd6, Pcp1
Domain Architecture
Description	Inositol 1,4,5-trisphosphate receptor type 1 (Type 1 inositol 1,4,5- trisphosphate receptor) (Type 1 InsP3 receptor) (IP3 receptor isoform 1) (InsP3R1) (Inositol 1,4,5-trisphosphate-binding protein P400) (Purkinje cell protein 1) (Protein PCD-6).

ITPR2_HUMAN
θ value	0 (rank : 3)	NC score	0.998677 (rank : 2)
Query Neighborhood Hits	69	Target Neighborhood Hits	74	Shared Neighborhood Hits	52
SwissProt Accessions	Q14571, O94773	Gene names	ITPR2
Domain Architecture
Description	Inositol 1,4,5-trisphosphate receptor type 2 (Type 2 inositol 1,4,5- trisphosphate receptor) (Type 2 InsP3 receptor) (IP3 receptor isoform 2) (InsP3R2).

ITPR2_MOUSE
θ value	0 (rank : 4)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	69	Target Neighborhood Hits	69	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Z329, P70226, Q5DWM3, Q5DWM5, Q61744, Q8R3B0	Gene names	Itpr2, Itpr5
Domain Architecture	No domain graphic available
Description	Inositol 1,4,5-trisphosphate receptor type 2 (Type 2 inositol 1,4,5- trisphosphate receptor) (Type 2 InsP3 receptor) (IP3 receptor isoform 2) (InsP3R2) (Inositol 1,4,5-trisphosphate type V receptor).

ITPR3_HUMAN
θ value	0 (rank : 5)	NC score	0.991022 (rank : 6)
Query Neighborhood Hits	69	Target Neighborhood Hits	114	Shared Neighborhood Hits	22
SwissProt Accessions	Q14573, Q14649	Gene names	ITPR3
Domain Architecture
Description	Inositol 1,4,5-trisphosphate receptor type 3 (Type 3 inositol 1,4,5- trisphosphate receptor) (Type 3 InsP3 receptor) (IP3 receptor isoform 3) (InsP3R3).

ITPR3_MOUSE
θ value	0 (rank : 6)	NC score	0.991617 (rank : 5)
Query Neighborhood Hits	69	Target Neighborhood Hits	105	Shared Neighborhood Hits	22
SwissProt Accessions	P70227, Q5DWM4, Q8CED5, Q91Z08	Gene names	Itpr3
Domain Architecture	No domain graphic available
Description	Inositol 1,4,5-trisphosphate receptor type 3 (Type 3 inositol 1,4,5- trisphosphate receptor) (Type 3 InsP3 receptor) (IP3 receptor isoform 3) (InsP3R3).

RYR1_HUMAN
θ value	5.97985e-28 (rank : 7)	NC score	0.535115 (rank : 8)
Query Neighborhood Hits	69	Target Neighborhood Hits	303	Shared Neighborhood Hits	13
SwissProt Accessions	P21817, Q16314, Q16368, Q9NPK1, Q9P1U4	Gene names	RYR1, RYDR
Domain Architecture
Description	Ryanodine receptor 1 (Skeletal muscle-type ryanodine receptor) (RyR1) (RYR-1) (Skeletal muscle calcium release channel).

RYR3_HUMAN
θ value	1.02001e-27 (rank : 8)	NC score	0.541929 (rank : 7)
Query Neighborhood Hits	69	Target Neighborhood Hits	134	Shared Neighborhood Hits	11
SwissProt Accessions	Q15413, O15175, Q15412	Gene names	RYR3, HBRR
Domain Architecture
Description	Ryanodine receptor 3 (Brain-type ryanodine receptor) (RyR3) (RYR-3) (Brain ryanodine receptor-calcium release channel).

RYR2_HUMAN
θ value	8.63488e-27 (rank : 9)	NC score	0.530770 (rank : 9)
Query Neighborhood Hits	69	Target Neighborhood Hits	175	Shared Neighborhood Hits	11
SwissProt Accessions	Q92736, Q15411, Q546N8	Gene names	RYR2
Domain Architecture
Description	Ryanodine receptor 2 (Cardiac muscle-type ryanodine receptor) (RyR2) (RYR-2) (Cardiac muscle ryanodine receptor-calcium release channel) (hRYR-2).

LRBA_HUMAN
θ value	0.365318 (rank : 10)	NC score	0.020820 (rank : 25)
Query Neighborhood Hits	69	Target Neighborhood Hits	196	Shared Neighborhood Hits	8
SwissProt Accessions	P50851, Q9H2U3, Q9H2U4	Gene names	LRBA, BGL, CDC4L, LBA
Domain Architecture
Description	Lipopolysaccharide-responsive and beige-like anchor protein (CDC4-like protein) (Beige-like protein).

CJ118_MOUSE
θ value	0.47712 (rank : 11)	NC score	0.035980 (rank : 10)
Query Neighborhood Hits	69	Target Neighborhood Hits	1132	Shared Neighborhood Hits	35
SwissProt Accessions	Q8C9S4, Q6P3D6, Q8CJC0	Gene names	Otg1
Domain Architecture	No domain graphic available
Description	Protein C10orf118 homolog (Oocyte-testis gene 1 protein).

CP2AC_MOUSE
θ value	0.47712 (rank : 12)	NC score	0.011054 (rank : 44)
Query Neighborhood Hits	69	Target Neighborhood Hits	110	Shared Neighborhood Hits	4
SwissProt Accessions	P56593	Gene names	Cyp2a12
Domain Architecture	No domain graphic available
Description	Cytochrome P450 2A12 (EC 1.14.14.1) (CYPIIA12) (Steroid hormones 7- alpha-hydroxylase) (Testosterone 7-alpha-hydroxylase).

CEP72_MOUSE
θ value	0.813845 (rank : 13)	NC score	0.028682 (rank : 14)
Query Neighborhood Hits	69	Target Neighborhood Hits	381	Shared Neighborhood Hits	19
SwissProt Accessions	Q9D3R3, Q8BM53, Q9D0B7	Gene names	Cep72
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 72 kDa (Cep72 protein).

GOGA4_HUMAN
θ value	0.813845 (rank : 14)	NC score	0.026051 (rank : 20)
Query Neighborhood Hits	69	Target Neighborhood Hits	2034	Shared Neighborhood Hits	32
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

KAD7_HUMAN
θ value	0.813845 (rank : 15)	NC score	0.026238 (rank : 19)
Query Neighborhood Hits	69	Target Neighborhood Hits	83	Shared Neighborhood Hits	7
SwissProt Accessions	Q96M32, Q8IYP6	Gene names	AK7
Domain Architecture
Description	Putative adenylate kinase 7 (EC 2.7.4.3).

MYO5A_MOUSE
θ value	0.813845 (rank : 16)	NC score	0.010229 (rank : 46)
Query Neighborhood Hits	69	Target Neighborhood Hits	1117	Shared Neighborhood Hits	26
SwissProt Accessions	Q99104	Gene names	Myo5a, Dilute
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle).

RABE1_HUMAN
θ value	0.813845 (rank : 17)	NC score	0.027210 (rank : 17)
Query Neighborhood Hits	69	Target Neighborhood Hits	1104	Shared Neighborhood Hits	30
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

RABE1_MOUSE
θ value	0.813845 (rank : 18)	NC score	0.024942 (rank : 21)
Query Neighborhood Hits	69	Target Neighborhood Hits	1105	Shared Neighborhood Hits	28
SwissProt Accessions	O35551, Q99L08, Q9CRP3, Q9EQF9, Q9JI94	Gene names	Rabep1, Rab5ep, Rabpt5, Rabpt5a
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha).

TRRAP_HUMAN
θ value	1.06291 (rank : 19)	NC score	0.031841 (rank : 12)
Query Neighborhood Hits	69	Target Neighborhood Hits	117	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y4A5, O75218, Q9Y631, Q9Y6H4	Gene names	TRRAP, PAF400
Domain Architecture
Description	Transformation/transcription domain-associated protein (350/400 kDa PCAF-associated factor) (PAF350/400) (STAF40) (Tra1 homolog).

ASB17_MOUSE
θ value	1.38821 (rank : 20)	NC score	0.030313 (rank : 13)
Query Neighborhood Hits	69	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VHP9, Q9CUF9	Gene names	Asb17
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 17 (ASB-17).

CJ118_HUMAN
θ value	1.38821 (rank : 21)	NC score	0.026607 (rank : 18)
Query Neighborhood Hits	69	Target Neighborhood Hits	937	Shared Neighborhood Hits	30
SwissProt Accessions	Q7Z3E2, Q2M2V6, Q6NS91, Q7RTP1, Q8N117, Q8N3G3, Q8N6C2, Q9NWA3	Gene names	C10orf118
Domain Architecture	No domain graphic available
Description	Protein C10orf118 (CTCL tumor antigen HD-CL-01/L14-2).

EP15_HUMAN
θ value	1.38821 (rank : 22)	NC score	0.033338 (rank : 11)
Query Neighborhood Hits	69	Target Neighborhood Hits	1021	Shared Neighborhood Hits	33
SwissProt Accessions	P42566	Gene names	EPS15, AF1P
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

BPAEA_MOUSE
θ value	1.81305 (rank : 23)	NC score	0.020101 (rank : 27)
Query Neighborhood Hits	69	Target Neighborhood Hits	1480	Shared Neighborhood Hits	30
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

GA45B_MOUSE
θ value	1.81305 (rank : 24)	NC score	0.028410 (rank : 16)
Query Neighborhood Hits	69	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	P22339, Q3U342, Q9R106	Gene names	Gadd45b, Myd118
Domain Architecture
Description	Growth arrest and DNA-damage-inducible protein GADD45 beta (Negative growth-regulatory protein MyD118) (Myeloid differentiation primary response protein MyD118).

OL139_MOUSE
θ value	1.81305 (rank : 25)	NC score	-0.000304 (rank : 69)
Query Neighborhood Hits	69	Target Neighborhood Hits	736	Shared Neighborhood Hits	3
SwissProt Accessions	Q60891, Q8VGR1, Q9EPY8	Gene names	Olfr139, Mor255-2, Olfr1
Domain Architecture	No domain graphic available
Description	Olfactory receptor 139 (Olfactory receptor 1) (Olfactory receptor 255- 2) (Odorant receptor M5).

TTLL5_HUMAN
θ value	1.81305 (rank : 26)	NC score	0.022925 (rank : 23)
Query Neighborhood Hits	69	Target Neighborhood Hits	141	Shared Neighborhood Hits	6
SwissProt Accessions	Q6EMB2, Q9P1V5, Q9UPZ4	Gene names	TTLL5, KIAA0998, STAMP
Domain Architecture	No domain graphic available
Description	Tubulin--tyrosine ligase-like protein 5 (SRC1 and TIF2-associated modulatory protein).

CHD6_HUMAN
θ value	2.36792 (rank : 27)	NC score	0.008968 (rank : 51)
Query Neighborhood Hits	69	Target Neighborhood Hits	342	Shared Neighborhood Hits	10
SwissProt Accessions	Q8TD26, Q5JYQ0, Q5TGZ9, Q5TH00, Q5TH01, Q8IZR2, Q8WTY0, Q9H4H6, Q9H6D4, Q9NTT7, Q9P2L1	Gene names	CHD6, CHD5, KIAA1335, RIGB
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein).

CP2A6_HUMAN
θ value	2.36792 (rank : 28)	NC score	0.007842 (rank : 52)
Query Neighborhood Hits	69	Target Neighborhood Hits	108	Shared Neighborhood Hits	4
SwissProt Accessions	P11509, P00190, P10890, Q16803, Q4VAT9, Q4VAU0, Q4VAU1, Q9H1Z7, Q9UK48	Gene names	CYP2A6
Domain Architecture
Description	Cytochrome P450 2A6 (EC 1.14.14.1) (CYPIIA6) (Coumarin 7-hydroxylase) (P450 IIA3) (CYP2A3) (P450(I)).

SRRM2_HUMAN
θ value	2.36792 (rank : 29)	NC score	0.007160 (rank : 54)
Query Neighborhood Hits	69	Target Neighborhood Hits	1296	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

ANR26_MOUSE
θ value	3.0926 (rank : 30)	NC score	0.015996 (rank : 34)
Query Neighborhood Hits	69	Target Neighborhood Hits	1554	Shared Neighborhood Hits	31
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

CKAP2_MOUSE
θ value	3.0926 (rank : 31)	NC score	0.020410 (rank : 26)
Query Neighborhood Hits	69	Target Neighborhood Hits	63	Shared Neighborhood Hits	6
SwissProt Accessions	Q3V1H1, Q66LN2, Q8BSF0	Gene names	Ckap2
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 2.

GCC2_HUMAN
θ value	3.0926 (rank : 32)	NC score	0.017172 (rank : 32)
Query Neighborhood Hits	69	Target Neighborhood Hits	1558	Shared Neighborhood Hits	31
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

LRC45_MOUSE
θ value	3.0926 (rank : 33)	NC score	0.021740 (rank : 24)
Query Neighborhood Hits	69	Target Neighborhood Hits	959	Shared Neighborhood Hits	29
SwissProt Accessions	Q8CIM1, Q3U5Z2	Gene names	Lrrc45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

RBP24_HUMAN
θ value	3.0926 (rank : 34)	NC score	0.017206 (rank : 31)
Query Neighborhood Hits	69	Target Neighborhood Hits	1559	Shared Neighborhood Hits	31
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

S26A6_HUMAN
θ value	3.0926 (rank : 35)	NC score	0.012691 (rank : 39)
Query Neighborhood Hits	69	Target Neighborhood Hits	32	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BXS9, Q96Q90	Gene names	SLC26A6
Domain Architecture
Description	Solute carrier family 26 member 6 (Pendrin-like protein 1) (Pendrin L1).

SC11A_MOUSE
θ value	3.0926 (rank : 36)	NC score	0.012672 (rank : 40)
Query Neighborhood Hits	69	Target Neighborhood Hits	116	Shared Neighborhood Hits	7
SwissProt Accessions	Q9R053, Q9JMD4	Gene names	Scn11a, Nan, Nat, Sns2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (NaN).

LRRC1_MOUSE
θ value	4.03905 (rank : 37)	NC score	0.006562 (rank : 59)
Query Neighborhood Hits	69	Target Neighborhood Hits	281	Shared Neighborhood Hits	5
SwissProt Accessions	Q80VQ1, Q3UI50, Q8BKR1, Q8BUS9	Gene names	Lrrc1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 1.

MIS12_HUMAN
θ value	4.03905 (rank : 38)	NC score	0.028426 (rank : 15)
Query Neighborhood Hits	69	Target Neighborhood Hits	52	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H081, Q96N24	Gene names	MIS12
Domain Architecture	No domain graphic available
Description	Protein MIS12 homolog.

TTLL5_MOUSE
θ value	4.03905 (rank : 39)	NC score	0.024886 (rank : 22)
Query Neighborhood Hits	69	Target Neighborhood Hits	150	Shared Neighborhood Hits	6
SwissProt Accessions	Q8CHB8	Gene names	Ttll5, Kiaa0998
Domain Architecture	No domain graphic available
Description	Tubulin--tyrosine ligase-like protein 5.

VDP_MOUSE
θ value	4.03905 (rank : 40)	NC score	0.019877 (rank : 28)
Query Neighborhood Hits	69	Target Neighborhood Hits	469	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Z1Z0, Q3T9L9, Q3TH58, Q3U1C7, Q3UMW6, Q91WE7, Q99JZ5	Gene names	Vdp
Domain Architecture	No domain graphic available
Description	General vesicular transport factor p115 (Transcytosis-associated protein) (TAP) (Vesicle docking protein).

WEE1_MOUSE
θ value	4.03905 (rank : 41)	NC score	0.000862 (rank : 67)
Query Neighborhood Hits	69	Target Neighborhood Hits	794	Shared Neighborhood Hits	6
SwissProt Accessions	P47810, Q9EPL7	Gene names	Wee1
Domain Architecture
Description	Wee1-like protein kinase (EC 2.7.10.2) (Wee1A kinase).

1433B_HUMAN
θ value	5.27518 (rank : 42)	NC score	0.007120 (rank : 56)
Query Neighborhood Hits	69	Target Neighborhood Hits	34	Shared Neighborhood Hits	4
SwissProt Accessions	P31946	Gene names	YWHAB
Domain Architecture
Description	14-3-3 protein beta/alpha (Protein kinase C inhibitor protein 1) (KCIP-1) (Protein 1054).

1433B_MOUSE
θ value	5.27518 (rank : 43)	NC score	0.007141 (rank : 55)
Query Neighborhood Hits	69	Target Neighborhood Hits	35	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CQV8, O70455, Q3TY33, Q3UAN6	Gene names	Ywhab
Domain Architecture
Description	14-3-3 protein beta/alpha (Protein kinase C inhibitor protein 1) (KCIP-1).

EP15_MOUSE
θ value	5.27518 (rank : 44)	NC score	0.013376 (rank : 38)
Query Neighborhood Hits	69	Target Neighborhood Hits	820	Shared Neighborhood Hits	28
SwissProt Accessions	P42567	Gene names	Eps15
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

K0406_MOUSE
θ value	5.27518 (rank : 45)	NC score	0.010705 (rank : 45)
Query Neighborhood Hits	69	Target Neighborhood Hits	20	Shared Neighborhood Hits	3
SwissProt Accessions	Q91V83, Q9CSY0	Gene names
Domain Architecture	No domain graphic available
Description	Protein KIAA0406 homolog.

P2RY1_MOUSE
θ value	5.27518 (rank : 46)	NC score	0.003001 (rank : 63)
Query Neighborhood Hits	69	Target Neighborhood Hits	591	Shared Neighborhood Hits	3
SwissProt Accessions	P49650	Gene names	P2ry1
Domain Architecture
Description	P2Y purinoceptor 1 (ATP receptor) (P2Y1) (Purinergic receptor).

SDK2_HUMAN
θ value	5.27518 (rank : 47)	NC score	0.001066 (rank : 66)
Query Neighborhood Hits	69	Target Neighborhood Hits	495	Shared Neighborhood Hits	2
SwissProt Accessions	Q58EX2, Q86VY3, Q9NTD2, Q9NVB3, Q9P214	Gene names	SDK2, KIAA1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

SMC2_HUMAN
θ value	5.27518 (rank : 48)	NC score	0.014494 (rank : 35)
Query Neighborhood Hits	69	Target Neighborhood Hits	1405	Shared Neighborhood Hits	31
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

T3JAM_MOUSE
θ value	5.27518 (rank : 49)	NC score	0.018469 (rank : 29)
Query Neighborhood Hits	69	Target Neighborhood Hits	535	Shared Neighborhood Hits	21
SwissProt Accessions	Q8C0G2, Q8BY50, Q8K1Y9	Gene names	Traf3ip3, T3jam
Domain Architecture	No domain graphic available
Description	TRAF3-interacting JNK-activating modulator (TRAF3-interacting protein 3).

CASL_HUMAN
θ value	6.88961 (rank : 50)	NC score	0.009603 (rank : 48)
Query Neighborhood Hits	69	Target Neighborhood Hits	259	Shared Neighborhood Hits	6
SwissProt Accessions	Q14511	Gene names	NEDD9, CASL
Domain Architecture
Description	Enhancer of filamentation 1 (HEF1) (CRK-associated substrate-related protein) (CAS-L) (CasL) (p105) (Protein NEDD9) (NY-REN-12 antigen).

CTRO_HUMAN
θ value	6.88961 (rank : 51)	NC score	0.007702 (rank : 53)
Query Neighborhood Hits	69	Target Neighborhood Hits	2092	Shared Neighborhood Hits	36
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

CTRO_MOUSE
θ value	6.88961 (rank : 52)	NC score	0.007006 (rank : 57)
Query Neighborhood Hits	69	Target Neighborhood Hits	2344	Shared Neighborhood Hits	36
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

DLG5_HUMAN
θ value	6.88961 (rank : 53)	NC score	0.016332 (rank : 33)
Query Neighborhood Hits	69	Target Neighborhood Hits	1088	Shared Neighborhood Hits	31
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

DYH11_HUMAN
θ value	6.88961 (rank : 54)	NC score	0.009101 (rank : 50)
Query Neighborhood Hits	69	Target Neighborhood Hits	234	Shared Neighborhood Hits	14
SwissProt Accessions	Q96DT5, Q9UJ82	Gene names	DNAH11
Domain Architecture
Description	Ciliary dynein heavy chain 11 (Axonemal beta dynein heavy chain 11).

GOGA4_MOUSE
θ value	6.88961 (rank : 55)	NC score	0.011763 (rank : 41)
Query Neighborhood Hits	69	Target Neighborhood Hits	1939	Shared Neighborhood Hits	31
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

HAPIP_HUMAN
θ value	6.88961 (rank : 56)	NC score	0.006528 (rank : 60)
Query Neighborhood Hits	69	Target Neighborhood Hits	350	Shared Neighborhood Hits	12
SwissProt Accessions	O60229	Gene names	HAPIP, DUO
Domain Architecture
Description	Huntingtin-associated protein-interacting protein (Protein Duo).

IF5_HUMAN
θ value	6.88961 (rank : 57)	NC score	0.009619 (rank : 47)
Query Neighborhood Hits	69	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	P55010, Q9H5N2, Q9UG48	Gene names	EIF5
Domain Architecture
Description	Eukaryotic translation initiation factor 5 (eIF-5).

K0100_HUMAN
θ value	6.88961 (rank : 58)	NC score	0.009108 (rank : 49)
Query Neighborhood Hits	69	Target Neighborhood Hits	132	Shared Neighborhood Hits	11
SwissProt Accessions	Q14667, Q3SYN5, Q49A07, Q5H9T4, Q6WG74, Q6ZP51, Q96HH8	Gene names	KIAA0100, BCOX1
Domain Architecture	No domain graphic available
Description	UPF0378 family protein KIAA0100 precursor (Breast cancer overexpressed gene 1 protein) (Antigen MLAA-22).

MYH14_MOUSE
θ value	6.88961 (rank : 59)	NC score	0.013824 (rank : 36)
Query Neighborhood Hits	69	Target Neighborhood Hits	1225	Shared Neighborhood Hits	34
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

PI3R6_HUMAN
θ value	6.88961 (rank : 60)	NC score	0.013508 (rank : 37)
Query Neighborhood Hits	69	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	Q5UE93, Q658R3	Gene names	PIK3R6, C17orf38
Domain Architecture	No domain graphic available
Description	Phosphoinositide 3-kinase regulatory subunit 6 (Phosphoinositide 3- kinase gamma adapter protein of 87 kDa) (p87 PI3K adapter protein) (p87PIKAP).

TRPA1_MOUSE
θ value	6.88961 (rank : 61)	NC score	0.003780 (rank : 62)
Query Neighborhood Hits	69	Target Neighborhood Hits	343	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BLA8	Gene names	Trpa1, Anktm1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1).

CD2L5_HUMAN
θ value	8.99809 (rank : 62)	NC score	0.002289 (rank : 65)
Query Neighborhood Hits	69	Target Neighborhood Hits	987	Shared Neighborhood Hits	10
SwissProt Accessions	Q14004, Q6DKQ9, Q75MH4, Q75MH5, Q96JN4, Q9H4A0, Q9H4A1, Q9UDR4	Gene names	CDC2L5, CDC2L, CHED, KIAA1791
Domain Architecture
Description	Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22) (CDC2- related protein kinase 5) (Cholinesterase-related cell division controller).

CD2L5_MOUSE
θ value	8.99809 (rank : 63)	NC score	0.002488 (rank : 64)
Query Neighborhood Hits	69	Target Neighborhood Hits	1011	Shared Neighborhood Hits	11
SwissProt Accessions	Q69ZA1, Q80V11, Q8BZG1, Q8K0A4	Gene names	Cdc2l5, Kiaa1791
Domain Architecture	No domain graphic available
Description	Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22) (CDC2- related protein kinase 5).

EMIL1_HUMAN
θ value	8.99809 (rank : 64)	NC score	0.006686 (rank : 58)
Query Neighborhood Hits	69	Target Neighborhood Hits	239	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y6C2, Q96G58, Q9UG76	Gene names	EMILIN1, EMI
Domain Architecture
Description	EMILIN-1 precursor (Elastin microfibril interface-located protein 1) (Elastin microfibril interfacer 1).

GAK_MOUSE
θ value	8.99809 (rank : 65)	NC score	0.000340 (rank : 68)
Query Neighborhood Hits	69	Target Neighborhood Hits	964	Shared Neighborhood Hits	7
SwissProt Accessions	Q99KY4, Q6P1I8, Q6P9S5, Q8BM74, Q8K0Q4	Gene names	Gak
Domain Architecture	No domain graphic available
Description	Cyclin G-associated kinase (EC 2.7.11.1).

HIP1R_MOUSE
θ value	8.99809 (rank : 66)	NC score	0.017940 (rank : 30)
Query Neighborhood Hits	69	Target Neighborhood Hits	959	Shared Neighborhood Hits	29
SwissProt Accessions	Q9JKY5	Gene names	Hip1r
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related).

K1143_MOUSE
θ value	8.99809 (rank : 67)	NC score	0.011194 (rank : 43)
Query Neighborhood Hits	69	Target Neighborhood Hits	48	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K039, Q9CSR4, Q9D0W8	Gene names
Domain Architecture	No domain graphic available
Description	Protein KIAA1143 homolog.

LRRC1_HUMAN
θ value	8.99809 (rank : 68)	NC score	0.004491 (rank : 61)
Query Neighborhood Hits	69	Target Neighborhood Hits	282	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BTT6, Q9HAC0, Q9NVF1	Gene names	LRRC1, LANO
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 1 (LAP and no PDZ protein) (LANO adapter protein).

SMC2_MOUSE
θ value	8.99809 (rank : 69)	NC score	0.011656 (rank : 42)
Query Neighborhood Hits	69	Target Neighborhood Hits	1131	Shared Neighborhood Hits	26
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

Hits sorted by NC score

ITPR2_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 4)
Query Neighborhood Hits	69	Target Neighborhood Hits	69	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Z329, P70226, Q5DWM3, Q5DWM5, Q61744, Q8R3B0	Gene names	Itpr2, Itpr5
Domain Architecture	No domain graphic available
Description	Inositol 1,4,5-trisphosphate receptor type 2 (Type 2 inositol 1,4,5- trisphosphate receptor) (Type 2 InsP3 receptor) (IP3 receptor isoform 2) (InsP3R2) (Inositol 1,4,5-trisphosphate type V receptor).

ITPR2_HUMAN
NC score	0.998677 (rank : 2)	θ value	0 (rank : 3)
Query Neighborhood Hits	69	Target Neighborhood Hits	74	Shared Neighborhood Hits	52
SwissProt Accessions	Q14571, O94773	Gene names	ITPR2
Domain Architecture
Description	Inositol 1,4,5-trisphosphate receptor type 2 (Type 2 inositol 1,4,5- trisphosphate receptor) (Type 2 InsP3 receptor) (IP3 receptor isoform 2) (InsP3R2).

ITPR1_HUMAN
NC score	0.993545 (rank : 3)	θ value	0 (rank : 1)
Query Neighborhood Hits	69	Target Neighborhood Hits	90	Shared Neighborhood Hits	23
SwissProt Accessions	Q14643, Q14660, Q99897	Gene names	ITPR1, INSP3R1
Domain Architecture
Description	Inositol 1,4,5-trisphosphate receptor type 1 (Type 1 inositol 1,4,5- trisphosphate receptor) (Type 1 InsP3 receptor) (IP3 receptor isoform 1) (InsP3R1) (IP3R).

ITPR1_MOUSE
NC score	0.993088 (rank : 4)	θ value	0 (rank : 2)
Query Neighborhood Hits	69	Target Neighborhood Hits	99	Shared Neighborhood Hits	24
SwissProt Accessions	P11881, P20943, Q99LG5	Gene names	Itpr1, Insp3r, Pcd6, Pcp1
Domain Architecture
Description	Inositol 1,4,5-trisphosphate receptor type 1 (Type 1 inositol 1,4,5- trisphosphate receptor) (Type 1 InsP3 receptor) (IP3 receptor isoform 1) (InsP3R1) (Inositol 1,4,5-trisphosphate-binding protein P400) (Purkinje cell protein 1) (Protein PCD-6).

ITPR3_MOUSE
NC score	0.991617 (rank : 5)	θ value	0 (rank : 6)
Query Neighborhood Hits	69	Target Neighborhood Hits	105	Shared Neighborhood Hits	22
SwissProt Accessions	P70227, Q5DWM4, Q8CED5, Q91Z08	Gene names	Itpr3
Domain Architecture	No domain graphic available
Description	Inositol 1,4,5-trisphosphate receptor type 3 (Type 3 inositol 1,4,5- trisphosphate receptor) (Type 3 InsP3 receptor) (IP3 receptor isoform 3) (InsP3R3).

ITPR3_HUMAN
NC score	0.991022 (rank : 6)	θ value	0 (rank : 5)
Query Neighborhood Hits	69	Target Neighborhood Hits	114	Shared Neighborhood Hits	22
SwissProt Accessions	Q14573, Q14649	Gene names	ITPR3
Domain Architecture
Description	Inositol 1,4,5-trisphosphate receptor type 3 (Type 3 inositol 1,4,5- trisphosphate receptor) (Type 3 InsP3 receptor) (IP3 receptor isoform 3) (InsP3R3).

RYR3_HUMAN
NC score	0.541929 (rank : 7)	θ value	1.02001e-27 (rank : 8)
Query Neighborhood Hits	69	Target Neighborhood Hits	134	Shared Neighborhood Hits	11
SwissProt Accessions	Q15413, O15175, Q15412	Gene names	RYR3, HBRR
Domain Architecture
Description	Ryanodine receptor 3 (Brain-type ryanodine receptor) (RyR3) (RYR-3) (Brain ryanodine receptor-calcium release channel).

RYR1_HUMAN
NC score	0.535115 (rank : 8)	θ value	5.97985e-28 (rank : 7)
Query Neighborhood Hits	69	Target Neighborhood Hits	303	Shared Neighborhood Hits	13
SwissProt Accessions	P21817, Q16314, Q16368, Q9NPK1, Q9P1U4	Gene names	RYR1, RYDR
Domain Architecture
Description	Ryanodine receptor 1 (Skeletal muscle-type ryanodine receptor) (RyR1) (RYR-1) (Skeletal muscle calcium release channel).

RYR2_HUMAN
NC score	0.530770 (rank : 9)	θ value	8.63488e-27 (rank : 9)
Query Neighborhood Hits	69	Target Neighborhood Hits	175	Shared Neighborhood Hits	11
SwissProt Accessions	Q92736, Q15411, Q546N8	Gene names	RYR2
Domain Architecture
Description	Ryanodine receptor 2 (Cardiac muscle-type ryanodine receptor) (RyR2) (RYR-2) (Cardiac muscle ryanodine receptor-calcium release channel) (hRYR-2).

CJ118_MOUSE
NC score	0.035980 (rank : 10)	θ value	0.47712 (rank : 11)
Query Neighborhood Hits	69	Target Neighborhood Hits	1132	Shared Neighborhood Hits	35
SwissProt Accessions	Q8C9S4, Q6P3D6, Q8CJC0	Gene names	Otg1
Domain Architecture	No domain graphic available
Description	Protein C10orf118 homolog (Oocyte-testis gene 1 protein).

EP15_HUMAN
NC score	0.033338 (rank : 11)	θ value	1.38821 (rank : 22)
Query Neighborhood Hits	69	Target Neighborhood Hits	1021	Shared Neighborhood Hits	33
SwissProt Accessions	P42566	Gene names	EPS15, AF1P
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

TRRAP_HUMAN
NC score	0.031841 (rank : 12)	θ value	1.06291 (rank : 19)
Query Neighborhood Hits	69	Target Neighborhood Hits	117	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Y4A5, O75218, Q9Y631, Q9Y6H4	Gene names	TRRAP, PAF400
Domain Architecture
Description	Transformation/transcription domain-associated protein (350/400 kDa PCAF-associated factor) (PAF350/400) (STAF40) (Tra1 homolog).

ASB17_MOUSE
NC score	0.030313 (rank : 13)	θ value	1.38821 (rank : 20)
Query Neighborhood Hits	69	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VHP9, Q9CUF9	Gene names	Asb17
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SOCS box protein 17 (ASB-17).

CEP72_MOUSE
NC score	0.028682 (rank : 14)	θ value	0.813845 (rank : 13)
Query Neighborhood Hits	69	Target Neighborhood Hits	381	Shared Neighborhood Hits	19
SwissProt Accessions	Q9D3R3, Q8BM53, Q9D0B7	Gene names	Cep72
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 72 kDa (Cep72 protein).

MIS12_HUMAN
NC score	0.028426 (rank : 15)	θ value	4.03905 (rank : 38)
Query Neighborhood Hits	69	Target Neighborhood Hits	52	Shared Neighborhood Hits	7
SwissProt Accessions	Q9H081, Q96N24	Gene names	MIS12
Domain Architecture	No domain graphic available
Description	Protein MIS12 homolog.

GA45B_MOUSE
NC score	0.028410 (rank : 16)	θ value	1.81305 (rank : 24)
Query Neighborhood Hits	69	Target Neighborhood Hits	9	Shared Neighborhood Hits	3
SwissProt Accessions	P22339, Q3U342, Q9R106	Gene names	Gadd45b, Myd118
Domain Architecture
Description	Growth arrest and DNA-damage-inducible protein GADD45 beta (Negative growth-regulatory protein MyD118) (Myeloid differentiation primary response protein MyD118).

RABE1_HUMAN
NC score	0.027210 (rank : 17)	θ value	0.813845 (rank : 17)
Query Neighborhood Hits	69	Target Neighborhood Hits	1104	Shared Neighborhood Hits	30
SwissProt Accessions	Q15276, O95369, Q8IVX3	Gene names	RABEP1, RABPT5, RABPT5A
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha) (Rabaptin-4) (NY-REN-17 antigen).

CJ118_HUMAN
NC score	0.026607 (rank : 18)	θ value	1.38821 (rank : 21)
Query Neighborhood Hits	69	Target Neighborhood Hits	937	Shared Neighborhood Hits	30
SwissProt Accessions	Q7Z3E2, Q2M2V6, Q6NS91, Q7RTP1, Q8N117, Q8N3G3, Q8N6C2, Q9NWA3	Gene names	C10orf118
Domain Architecture	No domain graphic available
Description	Protein C10orf118 (CTCL tumor antigen HD-CL-01/L14-2).

KAD7_HUMAN
NC score	0.026238 (rank : 19)	θ value	0.813845 (rank : 15)
Query Neighborhood Hits	69	Target Neighborhood Hits	83	Shared Neighborhood Hits	7
SwissProt Accessions	Q96M32, Q8IYP6	Gene names	AK7
Domain Architecture
Description	Putative adenylate kinase 7 (EC 2.7.4.3).

GOGA4_HUMAN
NC score	0.026051 (rank : 20)	θ value	0.813845 (rank : 14)
Query Neighborhood Hits	69	Target Neighborhood Hits	2034	Shared Neighborhood Hits	32
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

RABE1_MOUSE
NC score	0.024942 (rank : 21)	θ value	0.813845 (rank : 18)
Query Neighborhood Hits	69	Target Neighborhood Hits	1105	Shared Neighborhood Hits	28
SwissProt Accessions	O35551, Q99L08, Q9CRP3, Q9EQF9, Q9JI94	Gene names	Rabep1, Rab5ep, Rabpt5, Rabpt5a
Domain Architecture
Description	Rab GTPase-binding effector protein 1 (Rabaptin-5) (Rabaptin-5alpha).

TTLL5_MOUSE
NC score	0.024886 (rank : 22)	θ value	4.03905 (rank : 39)
Query Neighborhood Hits	69	Target Neighborhood Hits	150	Shared Neighborhood Hits	6
SwissProt Accessions	Q8CHB8	Gene names	Ttll5, Kiaa0998
Domain Architecture	No domain graphic available
Description	Tubulin--tyrosine ligase-like protein 5.

TTLL5_HUMAN
NC score	0.022925 (rank : 23)	θ value	1.81305 (rank : 26)
Query Neighborhood Hits	69	Target Neighborhood Hits	141	Shared Neighborhood Hits	6
SwissProt Accessions	Q6EMB2, Q9P1V5, Q9UPZ4	Gene names	TTLL5, KIAA0998, STAMP
Domain Architecture	No domain graphic available
Description	Tubulin--tyrosine ligase-like protein 5 (SRC1 and TIF2-associated modulatory protein).

LRC45_MOUSE
NC score	0.021740 (rank : 24)	θ value	3.0926 (rank : 33)
Query Neighborhood Hits	69	Target Neighborhood Hits	959	Shared Neighborhood Hits	29
SwissProt Accessions	Q8CIM1, Q3U5Z2	Gene names	Lrrc45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

LRBA_HUMAN
NC score	0.020820 (rank : 25)	θ value	0.365318 (rank : 10)
Query Neighborhood Hits	69	Target Neighborhood Hits	196	Shared Neighborhood Hits	8
SwissProt Accessions	P50851, Q9H2U3, Q9H2U4	Gene names	LRBA, BGL, CDC4L, LBA
Domain Architecture
Description	Lipopolysaccharide-responsive and beige-like anchor protein (CDC4-like protein) (Beige-like protein).

CKAP2_MOUSE
NC score	0.020410 (rank : 26)	θ value	3.0926 (rank : 31)
Query Neighborhood Hits	69	Target Neighborhood Hits	63	Shared Neighborhood Hits	6
SwissProt Accessions	Q3V1H1, Q66LN2, Q8BSF0	Gene names	Ckap2
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 2.

BPAEA_MOUSE
NC score	0.020101 (rank : 27)	θ value	1.81305 (rank : 23)
Query Neighborhood Hits	69	Target Neighborhood Hits	1480	Shared Neighborhood Hits	30
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

VDP_MOUSE
NC score	0.019877 (rank : 28)	θ value	4.03905 (rank : 40)
Query Neighborhood Hits	69	Target Neighborhood Hits	469	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Z1Z0, Q3T9L9, Q3TH58, Q3U1C7, Q3UMW6, Q91WE7, Q99JZ5	Gene names	Vdp
Domain Architecture	No domain graphic available
Description	General vesicular transport factor p115 (Transcytosis-associated protein) (TAP) (Vesicle docking protein).

T3JAM_MOUSE
NC score	0.018469 (rank : 29)	θ value	5.27518 (rank : 49)
Query Neighborhood Hits	69	Target Neighborhood Hits	535	Shared Neighborhood Hits	21
SwissProt Accessions	Q8C0G2, Q8BY50, Q8K1Y9	Gene names	Traf3ip3, T3jam
Domain Architecture	No domain graphic available
Description	TRAF3-interacting JNK-activating modulator (TRAF3-interacting protein 3).

HIP1R_MOUSE
NC score	0.017940 (rank : 30)	θ value	8.99809 (rank : 66)
Query Neighborhood Hits	69	Target Neighborhood Hits	959	Shared Neighborhood Hits	29
SwissProt Accessions	Q9JKY5	Gene names	Hip1r
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related).

RBP24_HUMAN
NC score	0.017206 (rank : 31)	θ value	3.0926 (rank : 34)
Query Neighborhood Hits	69	Target Neighborhood Hits	1559	Shared Neighborhood Hits	31
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

GCC2_HUMAN
NC score	0.017172 (rank : 32)	θ value	3.0926 (rank : 32)
Query Neighborhood Hits	69	Target Neighborhood Hits	1558	Shared Neighborhood Hits	31
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

DLG5_HUMAN
NC score	0.016332 (rank : 33)	θ value	6.88961 (rank : 53)
Query Neighborhood Hits	69	Target Neighborhood Hits	1088	Shared Neighborhood Hits	31
SwissProt Accessions	Q8TDM6, Q5T1H7, Q5T1H8, Q6DKG3, Q86WC0, Q8TDM7, Q9UE73, Q9Y4E3	Gene names	DLG5, KIAA0583, PDLG
Domain Architecture
Description	Discs large homolog 5 (Placenta and prostate DLG) (Discs large protein P-dlg).

ANR26_MOUSE
NC score	0.015996 (rank : 34)	θ value	3.0926 (rank : 30)
Query Neighborhood Hits	69	Target Neighborhood Hits	1554	Shared Neighborhood Hits	31
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

SMC2_HUMAN
NC score	0.014494 (rank : 35)	θ value	5.27518 (rank : 48)
Query Neighborhood Hits	69	Target Neighborhood Hits	1405	Shared Neighborhood Hits	31
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

MYH14_MOUSE
NC score	0.013824 (rank : 36)	θ value	6.88961 (rank : 59)
Query Neighborhood Hits	69	Target Neighborhood Hits	1225	Shared Neighborhood Hits	34
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

PI3R6_HUMAN
NC score	0.013508 (rank : 37)	θ value	6.88961 (rank : 60)
Query Neighborhood Hits	69	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	Q5UE93, Q658R3	Gene names	PIK3R6, C17orf38
Domain Architecture	No domain graphic available
Description	Phosphoinositide 3-kinase regulatory subunit 6 (Phosphoinositide 3- kinase gamma adapter protein of 87 kDa) (p87 PI3K adapter protein) (p87PIKAP).

EP15_MOUSE
NC score	0.013376 (rank : 38)	θ value	5.27518 (rank : 44)
Query Neighborhood Hits	69	Target Neighborhood Hits	820	Shared Neighborhood Hits	28
SwissProt Accessions	P42567	Gene names	Eps15
Domain Architecture
Description	Epidermal growth factor receptor substrate 15 (Protein Eps15) (AF-1p protein).

S26A6_HUMAN
NC score	0.012691 (rank : 39)	θ value	3.0926 (rank : 35)
Query Neighborhood Hits	69	Target Neighborhood Hits	32	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BXS9, Q96Q90	Gene names	SLC26A6
Domain Architecture
Description	Solute carrier family 26 member 6 (Pendrin-like protein 1) (Pendrin L1).

SC11A_MOUSE
NC score	0.012672 (rank : 40)	θ value	3.0926 (rank : 36)
Query Neighborhood Hits	69	Target Neighborhood Hits	116	Shared Neighborhood Hits	7
SwissProt Accessions	Q9R053, Q9JMD4	Gene names	Scn11a, Nan, Nat, Sns2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (NaN).

GOGA4_MOUSE
NC score	0.011763 (rank : 41)	θ value	6.88961 (rank : 55)
Query Neighborhood Hits	69	Target Neighborhood Hits	1939	Shared Neighborhood Hits	31
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

SMC2_MOUSE
NC score	0.011656 (rank : 42)	θ value	8.99809 (rank : 69)
Query Neighborhood Hits	69	Target Neighborhood Hits	1131	Shared Neighborhood Hits	26
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

K1143_MOUSE
NC score	0.011194 (rank : 43)	θ value	8.99809 (rank : 67)
Query Neighborhood Hits	69	Target Neighborhood Hits	48	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K039, Q9CSR4, Q9D0W8	Gene names
Domain Architecture	No domain graphic available
Description	Protein KIAA1143 homolog.

CP2AC_MOUSE
NC score	0.011054 (rank : 44)	θ value	0.47712 (rank : 12)
Query Neighborhood Hits	69	Target Neighborhood Hits	110	Shared Neighborhood Hits	4
SwissProt Accessions	P56593	Gene names	Cyp2a12
Domain Architecture	No domain graphic available
Description	Cytochrome P450 2A12 (EC 1.14.14.1) (CYPIIA12) (Steroid hormones 7- alpha-hydroxylase) (Testosterone 7-alpha-hydroxylase).

K0406_MOUSE
NC score	0.010705 (rank : 45)	θ value	5.27518 (rank : 45)
Query Neighborhood Hits	69	Target Neighborhood Hits	20	Shared Neighborhood Hits	3
SwissProt Accessions	Q91V83, Q9CSY0	Gene names
Domain Architecture	No domain graphic available
Description	Protein KIAA0406 homolog.

MYO5A_MOUSE
NC score	0.010229 (rank : 46)	θ value	0.813845 (rank : 16)
Query Neighborhood Hits	69	Target Neighborhood Hits	1117	Shared Neighborhood Hits	26
SwissProt Accessions	Q99104	Gene names	Myo5a, Dilute
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle).

IF5_HUMAN
NC score	0.009619 (rank : 47)	θ value	6.88961 (rank : 57)
Query Neighborhood Hits	69	Target Neighborhood Hits	36	Shared Neighborhood Hits	2
SwissProt Accessions	P55010, Q9H5N2, Q9UG48	Gene names	EIF5
Domain Architecture
Description	Eukaryotic translation initiation factor 5 (eIF-5).

CASL_HUMAN
NC score	0.009603 (rank : 48)	θ value	6.88961 (rank : 50)
Query Neighborhood Hits	69	Target Neighborhood Hits	259	Shared Neighborhood Hits	6
SwissProt Accessions	Q14511	Gene names	NEDD9, CASL
Domain Architecture
Description	Enhancer of filamentation 1 (HEF1) (CRK-associated substrate-related protein) (CAS-L) (CasL) (p105) (Protein NEDD9) (NY-REN-12 antigen).

K0100_HUMAN
NC score	0.009108 (rank : 49)	θ value	6.88961 (rank : 58)
Query Neighborhood Hits	69	Target Neighborhood Hits	132	Shared Neighborhood Hits	11
SwissProt Accessions	Q14667, Q3SYN5, Q49A07, Q5H9T4, Q6WG74, Q6ZP51, Q96HH8	Gene names	KIAA0100, BCOX1
Domain Architecture	No domain graphic available
Description	UPF0378 family protein KIAA0100 precursor (Breast cancer overexpressed gene 1 protein) (Antigen MLAA-22).

DYH11_HUMAN
NC score	0.009101 (rank : 50)	θ value	6.88961 (rank : 54)
Query Neighborhood Hits	69	Target Neighborhood Hits	234	Shared Neighborhood Hits	14
SwissProt Accessions	Q96DT5, Q9UJ82	Gene names	DNAH11
Domain Architecture
Description	Ciliary dynein heavy chain 11 (Axonemal beta dynein heavy chain 11).

CHD6_HUMAN
NC score	0.008968 (rank : 51)	θ value	2.36792 (rank : 27)
Query Neighborhood Hits	69	Target Neighborhood Hits	342	Shared Neighborhood Hits	10
SwissProt Accessions	Q8TD26, Q5JYQ0, Q5TGZ9, Q5TH00, Q5TH01, Q8IZR2, Q8WTY0, Q9H4H6, Q9H6D4, Q9NTT7, Q9P2L1	Gene names	CHD6, CHD5, KIAA1335, RIGB
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 6 (EC 3.6.1.-) (ATP- dependent helicase CHD6) (CHD-6) (Radiation-induced gene B protein).

CP2A6_HUMAN
NC score	0.007842 (rank : 52)	θ value	2.36792 (rank : 28)
Query Neighborhood Hits	69	Target Neighborhood Hits	108	Shared Neighborhood Hits	4
SwissProt Accessions	P11509, P00190, P10890, Q16803, Q4VAT9, Q4VAU0, Q4VAU1, Q9H1Z7, Q9UK48	Gene names	CYP2A6
Domain Architecture
Description	Cytochrome P450 2A6 (EC 1.14.14.1) (CYPIIA6) (Coumarin 7-hydroxylase) (P450 IIA3) (CYP2A3) (P450(I)).

CTRO_HUMAN
NC score	0.007702 (rank : 53)	θ value	6.88961 (rank : 51)
Query Neighborhood Hits	69	Target Neighborhood Hits	2092	Shared Neighborhood Hits	36
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

SRRM2_HUMAN
NC score	0.007160 (rank : 54)	θ value	2.36792 (rank : 29)
Query Neighborhood Hits	69	Target Neighborhood Hits	1296	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

1433B_MOUSE
NC score	0.007141 (rank : 55)	θ value	5.27518 (rank : 43)
Query Neighborhood Hits	69	Target Neighborhood Hits	35	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CQV8, O70455, Q3TY33, Q3UAN6	Gene names	Ywhab
Domain Architecture
Description	14-3-3 protein beta/alpha (Protein kinase C inhibitor protein 1) (KCIP-1).

1433B_HUMAN
NC score	0.007120 (rank : 56)	θ value	5.27518 (rank : 42)
Query Neighborhood Hits	69	Target Neighborhood Hits	34	Shared Neighborhood Hits	4
SwissProt Accessions	P31946	Gene names	YWHAB
Domain Architecture
Description	14-3-3 protein beta/alpha (Protein kinase C inhibitor protein 1) (KCIP-1) (Protein 1054).

CTRO_MOUSE
NC score	0.007006 (rank : 57)	θ value	6.88961 (rank : 52)
Query Neighborhood Hits	69	Target Neighborhood Hits	2344	Shared Neighborhood Hits	36
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

EMIL1_HUMAN
NC score	0.006686 (rank : 58)	θ value	8.99809 (rank : 64)
Query Neighborhood Hits	69	Target Neighborhood Hits	239	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y6C2, Q96G58, Q9UG76	Gene names	EMILIN1, EMI
Domain Architecture
Description	EMILIN-1 precursor (Elastin microfibril interface-located protein 1) (Elastin microfibril interfacer 1).

LRRC1_MOUSE
NC score	0.006562 (rank : 59)	θ value	4.03905 (rank : 37)
Query Neighborhood Hits	69	Target Neighborhood Hits	281	Shared Neighborhood Hits	5
SwissProt Accessions	Q80VQ1, Q3UI50, Q8BKR1, Q8BUS9	Gene names	Lrrc1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 1.

HAPIP_HUMAN
NC score	0.006528 (rank : 60)	θ value	6.88961 (rank : 56)
Query Neighborhood Hits	69	Target Neighborhood Hits	350	Shared Neighborhood Hits	12
SwissProt Accessions	O60229	Gene names	HAPIP, DUO
Domain Architecture
Description	Huntingtin-associated protein-interacting protein (Protein Duo).

LRRC1_HUMAN
NC score	0.004491 (rank : 61)	θ value	8.99809 (rank : 68)
Query Neighborhood Hits	69	Target Neighborhood Hits	282	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BTT6, Q9HAC0, Q9NVF1	Gene names	LRRC1, LANO
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 1 (LAP and no PDZ protein) (LANO adapter protein).

TRPA1_MOUSE
NC score	0.003780 (rank : 62)	θ value	6.88961 (rank : 61)
Query Neighborhood Hits	69	Target Neighborhood Hits	343	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BLA8	Gene names	Trpa1, Anktm1
Domain Architecture	No domain graphic available
Description	Transient receptor potential cation channel subfamily A member 1 (Ankyrin-like with transmembrane domains protein 1).

P2RY1_MOUSE
NC score	0.003001 (rank : 63)	θ value	5.27518 (rank : 46)
Query Neighborhood Hits	69	Target Neighborhood Hits	591	Shared Neighborhood Hits	3
SwissProt Accessions	P49650	Gene names	P2ry1
Domain Architecture
Description	P2Y purinoceptor 1 (ATP receptor) (P2Y1) (Purinergic receptor).

CD2L5_MOUSE
NC score	0.002488 (rank : 64)	θ value	8.99809 (rank : 63)
Query Neighborhood Hits	69	Target Neighborhood Hits	1011	Shared Neighborhood Hits	11
SwissProt Accessions	Q69ZA1, Q80V11, Q8BZG1, Q8K0A4	Gene names	Cdc2l5, Kiaa1791
Domain Architecture	No domain graphic available
Description	Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22) (CDC2- related protein kinase 5).

CD2L5_HUMAN
NC score	0.002289 (rank : 65)	θ value	8.99809 (rank : 62)
Query Neighborhood Hits	69	Target Neighborhood Hits	987	Shared Neighborhood Hits	10
SwissProt Accessions	Q14004, Q6DKQ9, Q75MH4, Q75MH5, Q96JN4, Q9H4A0, Q9H4A1, Q9UDR4	Gene names	CDC2L5, CDC2L, CHED, KIAA1791
Domain Architecture
Description	Cell division cycle 2-like protein kinase 5 (EC 2.7.11.22) (CDC2- related protein kinase 5) (Cholinesterase-related cell division controller).

SDK2_HUMAN
NC score	0.001066 (rank : 66)	θ value	5.27518 (rank : 47)
Query Neighborhood Hits	69	Target Neighborhood Hits	495	Shared Neighborhood Hits	2
SwissProt Accessions	Q58EX2, Q86VY3, Q9NTD2, Q9NVB3, Q9P214	Gene names	SDK2, KIAA1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

WEE1_MOUSE
NC score	0.000862 (rank : 67)	θ value	4.03905 (rank : 41)
Query Neighborhood Hits	69	Target Neighborhood Hits	794	Shared Neighborhood Hits	6
SwissProt Accessions	P47810, Q9EPL7	Gene names	Wee1
Domain Architecture
Description	Wee1-like protein kinase (EC 2.7.10.2) (Wee1A kinase).

GAK_MOUSE
NC score	0.000340 (rank : 68)	θ value	8.99809 (rank : 65)
Query Neighborhood Hits	69	Target Neighborhood Hits	964	Shared Neighborhood Hits	7
SwissProt Accessions	Q99KY4, Q6P1I8, Q6P9S5, Q8BM74, Q8K0Q4	Gene names	Gak
Domain Architecture	No domain graphic available
Description	Cyclin G-associated kinase (EC 2.7.11.1).

OL139_MOUSE
NC score	-0.000304 (rank : 69)	θ value	1.81305 (rank : 25)
Query Neighborhood Hits	69	Target Neighborhood Hits	736	Shared Neighborhood Hits	3
SwissProt Accessions	Q60891, Q8VGR1, Q9EPY8	Gene names	Olfr139, Mor255-2, Olfr1
Domain Architecture	No domain graphic available
Description	Olfactory receptor 139 (Olfactory receptor 1) (Olfactory receptor 255- 2) (Odorant receptor M5).