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Network neighborhood for query Sequence : IF5_HUMAN

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IF5_HUMAN
SwissProt Accessions	P55010, Q9H5N2, Q9UG48	Gene names	EIF5
Domain Architecture
Description	Eukaryotic translation initiation factor 5 (eIF-5).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

IF5_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	36	Target Neighborhood Hits	36	Shared Neighborhood Hits	36
SwissProt Accessions	P55010, Q9H5N2, Q9UG48	Gene names	EIF5
Domain Architecture
Description	Eukaryotic translation initiation factor 5 (eIF-5).

IF5_MOUSE
θ value	0 (rank : 2)	NC score	0.994639 (rank : 2)
Query Neighborhood Hits	36	Target Neighborhood Hits	35	Shared Neighborhood Hits	26
SwissProt Accessions	P59325	Gene names	Eif5
Domain Architecture
Description	Eukaryotic translation initiation factor 5 (eIF-5).

IF2B_HUMAN
θ value	7.59969e-07 (rank : 3)	NC score	0.379662 (rank : 3)
Query Neighborhood Hits	36	Target Neighborhood Hits	60	Shared Neighborhood Hits	8
SwissProt Accessions	P20042, Q9BVU0, Q9UJE4	Gene names	EIF2S2, EIF2B
Domain Architecture
Description	Eukaryotic translation initiation factor 2 subunit 2 (Eukaryotic translation initiation factor 2 subunit beta) (eIF-2-beta).

IF2B_MOUSE
θ value	7.59969e-07 (rank : 4)	NC score	0.378140 (rank : 4)
Query Neighborhood Hits	36	Target Neighborhood Hits	50	Shared Neighborhood Hits	4
SwissProt Accessions	Q99L45, Q9CSH6, Q9CT12	Gene names	Eif2s2
Domain Architecture
Description	Eukaryotic translation initiation factor 2 subunit 2 (Eukaryotic translation initiation factor 2 subunit beta) (eIF-2-beta).

EI2BE_HUMAN
θ value	0.00020696 (rank : 5)	NC score	0.268577 (rank : 5)
Query Neighborhood Hits	36	Target Neighborhood Hits	20	Shared Neighborhood Hits	9
SwissProt Accessions	Q13144, Q96D04	Gene names	EIF2B5, EIF2BE
Domain Architecture
Description	Translation initiation factor eIF-2B subunit epsilon (eIF-2B GDP-GTP exchange factor subunit epsilon).

EI2BE_MOUSE
θ value	0.000270298 (rank : 6)	NC score	0.265902 (rank : 6)
Query Neighborhood Hits	36	Target Neighborhood Hits	30	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CHW4, Q3TU39	Gene names	Eif2b5
Domain Architecture	No domain graphic available
Description	Translation initiation factor eIF-2B subunit epsilon (eIF-2B GDP-GTP exchange factor subunit epsilon).

IF4G1_HUMAN
θ value	0.0113563 (rank : 7)	NC score	0.154333 (rank : 7)
Query Neighborhood Hits	36	Target Neighborhood Hits	347	Shared Neighborhood Hits	11
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

IF4G1_MOUSE
θ value	0.0736092 (rank : 8)	NC score	0.141382 (rank : 8)
Query Neighborhood Hits	36	Target Neighborhood Hits	534	Shared Neighborhood Hits	12
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

IF4G3_MOUSE
θ value	0.365318 (rank : 9)	NC score	0.133756 (rank : 9)
Query Neighborhood Hits	36	Target Neighborhood Hits	279	Shared Neighborhood Hits	11
SwissProt Accessions	Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0	Gene names	Eif4g3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

PCLO_MOUSE
θ value	0.365318 (rank : 10)	NC score	0.023191 (rank : 28)
Query Neighborhood Hits	36	Target Neighborhood Hits	2275	Shared Neighborhood Hits	12
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

SMC1A_MOUSE
θ value	0.365318 (rank : 11)	NC score	0.034833 (rank : 22)
Query Neighborhood Hits	36	Target Neighborhood Hits	1384	Shared Neighborhood Hits	13
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

MORF4_HUMAN
θ value	0.47712 (rank : 12)	NC score	0.083101 (rank : 12)
Query Neighborhood Hits	36	Target Neighborhood Hits	15	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y690	Gene names	MORF4
Domain Architecture
Description	Transcription factor-like protein MORF4 (Mortality factor 4) (Cellular senescence-related protein 1) (SEN1).

VANG1_HUMAN
θ value	0.47712 (rank : 13)	NC score	0.072629 (rank : 16)
Query Neighborhood Hits	36	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TAA9, Q86WG8, Q8N559	Gene names	VANGL1, STB2
Domain Architecture
Description	Vang-like protein 1 (Van Gogh-like protein 1) (Strabismus 2) (Loop- tail protein 2 homolog) (LPP2).

IF4G3_HUMAN
θ value	0.62314 (rank : 14)	NC score	0.131081 (rank : 10)
Query Neighborhood Hits	36	Target Neighborhood Hits	247	Shared Neighborhood Hits	11
SwissProt Accessions	O43432, Q15597, Q8NEN1	Gene names	EIF4G3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

NEBL_HUMAN
θ value	0.813845 (rank : 15)	NC score	0.043352 (rank : 20)
Query Neighborhood Hits	36	Target Neighborhood Hits	457	Shared Neighborhood Hits	7
SwissProt Accessions	O76041, Q9UIC4	Gene names	NEBL
Domain Architecture
Description	Nebulette (Actin-binding Z-disk protein).

SMC1A_HUMAN
θ value	1.06291 (rank : 16)	NC score	0.030535 (rank : 24)
Query Neighborhood Hits	36	Target Neighborhood Hits	1346	Shared Neighborhood Hits	13
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

DPPA4_HUMAN
θ value	1.38821 (rank : 17)	NC score	0.041490 (rank : 21)
Query Neighborhood Hits	36	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	Q7L190, Q9H9N5, Q9NVI6	Gene names	DPPA4
Domain Architecture	No domain graphic available
Description	Developmental pluripotency-associated protein 4.

DUET_HUMAN
θ value	1.38821 (rank : 18)	NC score	0.004753 (rank : 36)
Query Neighborhood Hits	36	Target Neighborhood Hits	1220	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y2A5, Q8TBQ5, Q9NSZ4	Gene names	DUET, TRAD
Domain Architecture
Description	Serine/threonine-protein kinase Duet (EC 2.7.11.1) (Serine/threonine kinase with Dbl- and pleckstrin homology domain).

OXRP_HUMAN
θ value	1.38821 (rank : 19)	NC score	0.022230 (rank : 29)
Query Neighborhood Hits	36	Target Neighborhood Hits	544	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

SIN3B_HUMAN
θ value	1.81305 (rank : 20)	NC score	0.034461 (rank : 23)
Query Neighborhood Hits	36	Target Neighborhood Hits	82	Shared Neighborhood Hits	6
SwissProt Accessions	O75182, Q68GC2, Q6P4B8, Q8TB34, Q9BSC8	Gene names	SIN3B, KIAA0700
Domain Architecture
Description	Paired amphipathic helix protein Sin3b (Transcriptional corepressor Sin3b) (Histone deacetylase complex subunit Sin3b).

VANG1_MOUSE
θ value	2.36792 (rank : 21)	NC score	0.061095 (rank : 17)
Query Neighborhood Hits	36	Target Neighborhood Hits	7	Shared Neighborhood Hits	4
SwissProt Accessions	Q80Z96, Q8QZT3	Gene names	Vangl1, Lpp2
Domain Architecture
Description	Vang-like protein 1 (Van Gogh-like protein 1) (Loop-tail protein 2).

BPA1_MOUSE
θ value	3.0926 (rank : 22)	NC score	0.011088 (rank : 32)
Query Neighborhood Hits	36	Target Neighborhood Hits	1477	Shared Neighborhood Hits	9
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

MO4L1_HUMAN
θ value	3.0926 (rank : 23)	NC score	0.073538 (rank : 14)
Query Neighborhood Hits	36	Target Neighborhood Hits	51	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UBU8, O95899, Q5QTS1, Q6NVX8, Q86YT7, Q9HBP6, Q9NSW5	Gene names	MORF4L1, MRG15
Domain Architecture
Description	Mortality factor 4-like protein 1 (MORF-related gene 15 protein) (Transcription factor-like protein MRG15) (MSL3-1 protein).

MO4L1_MOUSE
θ value	3.0926 (rank : 24)	NC score	0.073522 (rank : 15)
Query Neighborhood Hits	36	Target Neighborhood Hits	51	Shared Neighborhood Hits	7
SwissProt Accessions	P60762, Q8BNY9, Q99MQ0	Gene names	Morf4l1, Mrg15, Tex189
Domain Architecture
Description	Mortality factor 4-like protein 1 (MORF-related gene 15 protein) (Transcription factor-like protein MRG15) (Testis-expressed gene 189 protein).

RBBP6_MOUSE
θ value	3.0926 (rank : 25)	NC score	0.021375 (rank : 30)
Query Neighborhood Hits	36	Target Neighborhood Hits	1014	Shared Neighborhood Hits	9
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

ZN619_HUMAN
θ value	4.03905 (rank : 26)	NC score	0.002267 (rank : 37)
Query Neighborhood Hits	36	Target Neighborhood Hits	749	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N2I2	Gene names	ZNF619
Domain Architecture	No domain graphic available
Description	Zinc finger protein 619.

APLP2_MOUSE
θ value	5.27518 (rank : 27)	NC score	0.017638 (rank : 31)
Query Neighborhood Hits	36	Target Neighborhood Hits	186	Shared Neighborhood Hits	3
SwissProt Accessions	Q06335	Gene names	Aplp2
Domain Architecture
Description	Amyloid-like protein 2 precursor (CDEI box-binding protein) (CDEBP).

CCD50_HUMAN
θ value	5.27518 (rank : 28)	NC score	0.025344 (rank : 27)
Query Neighborhood Hits	36	Target Neighborhood Hits	237	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IVM0, Q86VH7	Gene names	CCDC50, C3orf6
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 50 (Protein Ymer).

CSMD3_HUMAN
θ value	5.27518 (rank : 29)	NC score	0.010890 (rank : 33)
Query Neighborhood Hits	36	Target Neighborhood Hits	199	Shared Neighborhood Hits	3
SwissProt Accessions	Q7Z407, Q96PZ3	Gene names	CSMD3, KIAA1894
Domain Architecture
Description	CUB and sushi domain-containing protein 3 precursor (CUB and sushi multiple domains protein 3).

IF4G2_MOUSE
θ value	5.27518 (rank : 30)	NC score	0.095848 (rank : 11)
Query Neighborhood Hits	36	Target Neighborhood Hits	45	Shared Neighborhood Hits	9
SwissProt Accessions	Q62448, P97867, Q921U3	Gene names	Eif4g2, Nat1
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 2 (eIF-4-gamma 2) (eIF-4G 2) (eIF4G 2) (p97) (Novel APOBEC-1 target 1) (Translation repressor NAT1).

ZBT17_MOUSE
θ value	5.27518 (rank : 31)	NC score	0.000796 (rank : 38)
Query Neighborhood Hits	36	Target Neighborhood Hits	940	Shared Neighborhood Hits	4
SwissProt Accessions	Q60821, Q60699	Gene names	Zbtb17, Zfp100, Znf151
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 17 (Zinc finger protein 151) (Zinc finger protein 100) (Zfp-100) (Polyomavirus late initiator promoter-binding protein) (LP-1) (Zinc finger protein Z13).

IF39_HUMAN
θ value	6.88961 (rank : 32)	NC score	0.026411 (rank : 26)
Query Neighborhood Hits	36	Target Neighborhood Hits	187	Shared Neighborhood Hits	4
SwissProt Accessions	P55884, Q9UMF9	Gene names	EIF3S9
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 9 (eIF-3 eta) (eIF3 p116) (eIF3 p110) (eIF3b) (Prt1 homolog) (hPrt1).

ITPR2_MOUSE
θ value	6.88961 (rank : 33)	NC score	0.009619 (rank : 35)
Query Neighborhood Hits	36	Target Neighborhood Hits	69	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z329, P70226, Q5DWM3, Q5DWM5, Q61744, Q8R3B0	Gene names	Itpr2, Itpr5
Domain Architecture	No domain graphic available
Description	Inositol 1,4,5-trisphosphate receptor type 2 (Type 2 inositol 1,4,5- trisphosphate receptor) (Type 2 InsP3 receptor) (IP3 receptor isoform 2) (InsP3R2) (Inositol 1,4,5-trisphosphate type V receptor).

MO4L2_HUMAN
θ value	6.88961 (rank : 34)	NC score	0.060129 (rank : 18)
Query Neighborhood Hits	36	Target Neighborhood Hits	90	Shared Neighborhood Hits	7
SwissProt Accessions	Q15014, Q567V0, Q8J026	Gene names	MORF4L2, KIAA0026, MRGX
Domain Architecture
Description	Mortality factor 4-like protein 2 (MORF-related gene X protein) (Transcription factor-like protein MRGX) (MSL3-2 protein).

NASP_HUMAN
θ value	6.88961 (rank : 35)	NC score	0.027705 (rank : 25)
Query Neighborhood Hits	36	Target Neighborhood Hits	709	Shared Neighborhood Hits	11
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

AFAD_HUMAN
θ value	8.99809 (rank : 36)	NC score	0.009922 (rank : 34)
Query Neighborhood Hits	36	Target Neighborhood Hits	689	Shared Neighborhood Hits	6
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

IF4G2_HUMAN
θ value	θ > 10 (rank : 37)	NC score	0.079568 (rank : 13)
Query Neighborhood Hits	36	Target Neighborhood Hits	47	Shared Neighborhood Hits	7
SwissProt Accessions	P78344, O60877, P78404, Q53EU1, Q58EZ2, Q8NI71, Q96C16	Gene names	EIF4G2, DAP5
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 2 (eIF-4-gamma 2) (eIF-4G 2) (eIF4G 2) (p97) (Death-associated protein 5) (DAP-5).

MO4L2_MOUSE
θ value	θ > 10 (rank : 38)	NC score	0.051009 (rank : 19)
Query Neighborhood Hits	36	Target Neighborhood Hits	86	Shared Neighborhood Hits	6
SwissProt Accessions	Q9R0Q4, Q3UL62, Q6DIB1, Q6ZQK7, Q8C201, Q8C6C2	Gene names	Morf4l2, Kiaa0026, Sid393
Domain Architecture	No domain graphic available
Description	Mortality factor 4-like protein 2 (MORF-related gene X protein) (Transcription factor-like protein MRGX) (Sid 393).

Hits sorted by NC score

IF5_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	36	Target Neighborhood Hits	36	Shared Neighborhood Hits	36
SwissProt Accessions	P55010, Q9H5N2, Q9UG48	Gene names	EIF5
Domain Architecture
Description	Eukaryotic translation initiation factor 5 (eIF-5).

IF5_MOUSE
NC score	0.994639 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	36	Target Neighborhood Hits	35	Shared Neighborhood Hits	26
SwissProt Accessions	P59325	Gene names	Eif5
Domain Architecture
Description	Eukaryotic translation initiation factor 5 (eIF-5).

IF2B_HUMAN
NC score	0.379662 (rank : 3)	θ value	7.59969e-07 (rank : 3)
Query Neighborhood Hits	36	Target Neighborhood Hits	60	Shared Neighborhood Hits	8
SwissProt Accessions	P20042, Q9BVU0, Q9UJE4	Gene names	EIF2S2, EIF2B
Domain Architecture
Description	Eukaryotic translation initiation factor 2 subunit 2 (Eukaryotic translation initiation factor 2 subunit beta) (eIF-2-beta).

IF2B_MOUSE
NC score	0.378140 (rank : 4)	θ value	7.59969e-07 (rank : 4)
Query Neighborhood Hits	36	Target Neighborhood Hits	50	Shared Neighborhood Hits	4
SwissProt Accessions	Q99L45, Q9CSH6, Q9CT12	Gene names	Eif2s2
Domain Architecture
Description	Eukaryotic translation initiation factor 2 subunit 2 (Eukaryotic translation initiation factor 2 subunit beta) (eIF-2-beta).

EI2BE_HUMAN
NC score	0.268577 (rank : 5)	θ value	0.00020696 (rank : 5)
Query Neighborhood Hits	36	Target Neighborhood Hits	20	Shared Neighborhood Hits	9
SwissProt Accessions	Q13144, Q96D04	Gene names	EIF2B5, EIF2BE
Domain Architecture
Description	Translation initiation factor eIF-2B subunit epsilon (eIF-2B GDP-GTP exchange factor subunit epsilon).

EI2BE_MOUSE
NC score	0.265902 (rank : 6)	θ value	0.000270298 (rank : 6)
Query Neighborhood Hits	36	Target Neighborhood Hits	30	Shared Neighborhood Hits	9
SwissProt Accessions	Q8CHW4, Q3TU39	Gene names	Eif2b5
Domain Architecture	No domain graphic available
Description	Translation initiation factor eIF-2B subunit epsilon (eIF-2B GDP-GTP exchange factor subunit epsilon).

IF4G1_HUMAN
NC score	0.154333 (rank : 7)	θ value	0.0113563 (rank : 7)
Query Neighborhood Hits	36	Target Neighborhood Hits	347	Shared Neighborhood Hits	11
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

IF4G1_MOUSE
NC score	0.141382 (rank : 8)	θ value	0.0736092 (rank : 8)
Query Neighborhood Hits	36	Target Neighborhood Hits	534	Shared Neighborhood Hits	12
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

IF4G3_MOUSE
NC score	0.133756 (rank : 9)	θ value	0.365318 (rank : 9)
Query Neighborhood Hits	36	Target Neighborhood Hits	279	Shared Neighborhood Hits	11
SwissProt Accessions	Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0	Gene names	Eif4g3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

IF4G3_HUMAN
NC score	0.131081 (rank : 10)	θ value	0.62314 (rank : 14)
Query Neighborhood Hits	36	Target Neighborhood Hits	247	Shared Neighborhood Hits	11
SwissProt Accessions	O43432, Q15597, Q8NEN1	Gene names	EIF4G3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

IF4G2_MOUSE
NC score	0.095848 (rank : 11)	θ value	5.27518 (rank : 30)
Query Neighborhood Hits	36	Target Neighborhood Hits	45	Shared Neighborhood Hits	9
SwissProt Accessions	Q62448, P97867, Q921U3	Gene names	Eif4g2, Nat1
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 2 (eIF-4-gamma 2) (eIF-4G 2) (eIF4G 2) (p97) (Novel APOBEC-1 target 1) (Translation repressor NAT1).

MORF4_HUMAN
NC score	0.083101 (rank : 12)	θ value	0.47712 (rank : 12)
Query Neighborhood Hits	36	Target Neighborhood Hits	15	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y690	Gene names	MORF4
Domain Architecture
Description	Transcription factor-like protein MORF4 (Mortality factor 4) (Cellular senescence-related protein 1) (SEN1).

IF4G2_HUMAN
NC score	0.079568 (rank : 13)	θ value	θ > 10 (rank : 37)
Query Neighborhood Hits	36	Target Neighborhood Hits	47	Shared Neighborhood Hits	7
SwissProt Accessions	P78344, O60877, P78404, Q53EU1, Q58EZ2, Q8NI71, Q96C16	Gene names	EIF4G2, DAP5
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 2 (eIF-4-gamma 2) (eIF-4G 2) (eIF4G 2) (p97) (Death-associated protein 5) (DAP-5).

MO4L1_HUMAN
NC score	0.073538 (rank : 14)	θ value	3.0926 (rank : 23)
Query Neighborhood Hits	36	Target Neighborhood Hits	51	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UBU8, O95899, Q5QTS1, Q6NVX8, Q86YT7, Q9HBP6, Q9NSW5	Gene names	MORF4L1, MRG15
Domain Architecture
Description	Mortality factor 4-like protein 1 (MORF-related gene 15 protein) (Transcription factor-like protein MRG15) (MSL3-1 protein).

MO4L1_MOUSE
NC score	0.073522 (rank : 15)	θ value	3.0926 (rank : 24)
Query Neighborhood Hits	36	Target Neighborhood Hits	51	Shared Neighborhood Hits	7
SwissProt Accessions	P60762, Q8BNY9, Q99MQ0	Gene names	Morf4l1, Mrg15, Tex189
Domain Architecture
Description	Mortality factor 4-like protein 1 (MORF-related gene 15 protein) (Transcription factor-like protein MRG15) (Testis-expressed gene 189 protein).

VANG1_HUMAN
NC score	0.072629 (rank : 16)	θ value	0.47712 (rank : 13)
Query Neighborhood Hits	36	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TAA9, Q86WG8, Q8N559	Gene names	VANGL1, STB2
Domain Architecture
Description	Vang-like protein 1 (Van Gogh-like protein 1) (Strabismus 2) (Loop- tail protein 2 homolog) (LPP2).

VANG1_MOUSE
NC score	0.061095 (rank : 17)	θ value	2.36792 (rank : 21)
Query Neighborhood Hits	36	Target Neighborhood Hits	7	Shared Neighborhood Hits	4
SwissProt Accessions	Q80Z96, Q8QZT3	Gene names	Vangl1, Lpp2
Domain Architecture
Description	Vang-like protein 1 (Van Gogh-like protein 1) (Loop-tail protein 2).

MO4L2_HUMAN
NC score	0.060129 (rank : 18)	θ value	6.88961 (rank : 34)
Query Neighborhood Hits	36	Target Neighborhood Hits	90	Shared Neighborhood Hits	7
SwissProt Accessions	Q15014, Q567V0, Q8J026	Gene names	MORF4L2, KIAA0026, MRGX
Domain Architecture
Description	Mortality factor 4-like protein 2 (MORF-related gene X protein) (Transcription factor-like protein MRGX) (MSL3-2 protein).

MO4L2_MOUSE
NC score	0.051009 (rank : 19)	θ value	θ > 10 (rank : 38)
Query Neighborhood Hits	36	Target Neighborhood Hits	86	Shared Neighborhood Hits	6
SwissProt Accessions	Q9R0Q4, Q3UL62, Q6DIB1, Q6ZQK7, Q8C201, Q8C6C2	Gene names	Morf4l2, Kiaa0026, Sid393
Domain Architecture	No domain graphic available
Description	Mortality factor 4-like protein 2 (MORF-related gene X protein) (Transcription factor-like protein MRGX) (Sid 393).

NEBL_HUMAN
NC score	0.043352 (rank : 20)	θ value	0.813845 (rank : 15)
Query Neighborhood Hits	36	Target Neighborhood Hits	457	Shared Neighborhood Hits	7
SwissProt Accessions	O76041, Q9UIC4	Gene names	NEBL
Domain Architecture
Description	Nebulette (Actin-binding Z-disk protein).

DPPA4_HUMAN
NC score	0.041490 (rank : 21)	θ value	1.38821 (rank : 17)
Query Neighborhood Hits	36	Target Neighborhood Hits	20	Shared Neighborhood Hits	2
SwissProt Accessions	Q7L190, Q9H9N5, Q9NVI6	Gene names	DPPA4
Domain Architecture	No domain graphic available
Description	Developmental pluripotency-associated protein 4.

SMC1A_MOUSE
NC score	0.034833 (rank : 22)	θ value	0.365318 (rank : 11)
Query Neighborhood Hits	36	Target Neighborhood Hits	1384	Shared Neighborhood Hits	13
SwissProt Accessions	Q9CU62, Q3V480, Q9CUX9, Q9D959, Q9WTU1	Gene names	Smc1l1, Sb1.8, Smc1, Smcb
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Chromosome segregation protein SmcB) (Sb1.8).

SIN3B_HUMAN
NC score	0.034461 (rank : 23)	θ value	1.81305 (rank : 20)
Query Neighborhood Hits	36	Target Neighborhood Hits	82	Shared Neighborhood Hits	6
SwissProt Accessions	O75182, Q68GC2, Q6P4B8, Q8TB34, Q9BSC8	Gene names	SIN3B, KIAA0700
Domain Architecture
Description	Paired amphipathic helix protein Sin3b (Transcriptional corepressor Sin3b) (Histone deacetylase complex subunit Sin3b).

SMC1A_HUMAN
NC score	0.030535 (rank : 24)	θ value	1.06291 (rank : 16)
Query Neighborhood Hits	36	Target Neighborhood Hits	1346	Shared Neighborhood Hits	13
SwissProt Accessions	Q14683, O14995, Q16351	Gene names	SMC1L1, DXS423E, KIAA0178, SB1.8, SMC1
Domain Architecture
Description	Structural maintenance of chromosome 1-like 1 protein (SMC1alpha protein) (Sb1.8).

NASP_HUMAN
NC score	0.027705 (rank : 25)	θ value	6.88961 (rank : 35)
Query Neighborhood Hits	36	Target Neighborhood Hits	709	Shared Neighborhood Hits	11
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

IF39_HUMAN
NC score	0.026411 (rank : 26)	θ value	6.88961 (rank : 32)
Query Neighborhood Hits	36	Target Neighborhood Hits	187	Shared Neighborhood Hits	4
SwissProt Accessions	P55884, Q9UMF9	Gene names	EIF3S9
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 9 (eIF-3 eta) (eIF3 p116) (eIF3 p110) (eIF3b) (Prt1 homolog) (hPrt1).

CCD50_HUMAN
NC score	0.025344 (rank : 27)	θ value	5.27518 (rank : 28)
Query Neighborhood Hits	36	Target Neighborhood Hits	237	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IVM0, Q86VH7	Gene names	CCDC50, C3orf6
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 50 (Protein Ymer).

PCLO_MOUSE
NC score	0.023191 (rank : 28)	θ value	0.365318 (rank : 10)
Query Neighborhood Hits	36	Target Neighborhood Hits	2275	Shared Neighborhood Hits	12
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

OXRP_HUMAN
NC score	0.022230 (rank : 29)	θ value	1.38821 (rank : 19)
Query Neighborhood Hits	36	Target Neighborhood Hits	544	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y4L1	Gene names	HYOU1, ORP150
Domain Architecture
Description	150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia up- regulated 1).

RBBP6_MOUSE
NC score	0.021375 (rank : 30)	θ value	3.0926 (rank : 25)
Query Neighborhood Hits	36	Target Neighborhood Hits	1014	Shared Neighborhood Hits	9
SwissProt Accessions	P97868, P70287, Q3TTR9, Q3TUM7, Q3UMP7, Q4U217, Q7TT06, Q8BNY8, Q8R399	Gene names	Rbbp6, P2pr, Pact
Domain Architecture	No domain graphic available
Description	Retinoblastoma-binding protein 6 (p53-associated cellular protein of testis) (Proliferation potential-related protein) (Protein P2P-R).

APLP2_MOUSE
NC score	0.017638 (rank : 31)	θ value	5.27518 (rank : 27)
Query Neighborhood Hits	36	Target Neighborhood Hits	186	Shared Neighborhood Hits	3
SwissProt Accessions	Q06335	Gene names	Aplp2
Domain Architecture
Description	Amyloid-like protein 2 precursor (CDEI box-binding protein) (CDEBP).

BPA1_MOUSE
NC score	0.011088 (rank : 32)	θ value	3.0926 (rank : 22)
Query Neighborhood Hits	36	Target Neighborhood Hits	1477	Shared Neighborhood Hits	9
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CSMD3_HUMAN
NC score	0.010890 (rank : 33)	θ value	5.27518 (rank : 29)
Query Neighborhood Hits	36	Target Neighborhood Hits	199	Shared Neighborhood Hits	3
SwissProt Accessions	Q7Z407, Q96PZ3	Gene names	CSMD3, KIAA1894
Domain Architecture
Description	CUB and sushi domain-containing protein 3 precursor (CUB and sushi multiple domains protein 3).

AFAD_HUMAN
NC score	0.009922 (rank : 34)	θ value	8.99809 (rank : 36)
Query Neighborhood Hits	36	Target Neighborhood Hits	689	Shared Neighborhood Hits	6
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

ITPR2_MOUSE
NC score	0.009619 (rank : 35)	θ value	6.88961 (rank : 33)
Query Neighborhood Hits	36	Target Neighborhood Hits	69	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z329, P70226, Q5DWM3, Q5DWM5, Q61744, Q8R3B0	Gene names	Itpr2, Itpr5
Domain Architecture	No domain graphic available
Description	Inositol 1,4,5-trisphosphate receptor type 2 (Type 2 inositol 1,4,5- trisphosphate receptor) (Type 2 InsP3 receptor) (IP3 receptor isoform 2) (InsP3R2) (Inositol 1,4,5-trisphosphate type V receptor).

DUET_HUMAN
NC score	0.004753 (rank : 36)	θ value	1.38821 (rank : 18)
Query Neighborhood Hits	36	Target Neighborhood Hits	1220	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y2A5, Q8TBQ5, Q9NSZ4	Gene names	DUET, TRAD
Domain Architecture
Description	Serine/threonine-protein kinase Duet (EC 2.7.11.1) (Serine/threonine kinase with Dbl- and pleckstrin homology domain).

ZN619_HUMAN
NC score	0.002267 (rank : 37)	θ value	4.03905 (rank : 26)
Query Neighborhood Hits	36	Target Neighborhood Hits	749	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N2I2	Gene names	ZNF619
Domain Architecture	No domain graphic available
Description	Zinc finger protein 619.

ZBT17_MOUSE
NC score	0.000796 (rank : 38)	θ value	5.27518 (rank : 31)
Query Neighborhood Hits	36	Target Neighborhood Hits	940	Shared Neighborhood Hits	4
SwissProt Accessions	Q60821, Q60699	Gene names	Zbtb17, Zfp100, Znf151
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 17 (Zinc finger protein 151) (Zinc finger protein 100) (Zfp-100) (Polyomavirus late initiator promoter-binding protein) (LP-1) (Zinc finger protein Z13).