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Network neighborhood for query Sequence : IF4G2_HUMAN

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IF4G2_HUMAN
SwissProt Accessions	P78344, O60877, P78404, Q53EU1, Q58EZ2, Q8NI71, Q96C16	Gene names	EIF4G2, DAP5
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 2 (eIF-4-gamma 2) (eIF-4G 2) (eIF4G 2) (p97) (Death-associated protein 5) (DAP-5).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

IF4G2_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	47	Target Neighborhood Hits	47	Shared Neighborhood Hits	47
SwissProt Accessions	P78344, O60877, P78404, Q53EU1, Q58EZ2, Q8NI71, Q96C16	Gene names	EIF4G2, DAP5
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 2 (eIF-4-gamma 2) (eIF-4G 2) (eIF4G 2) (p97) (Death-associated protein 5) (DAP-5).

IF4G2_MOUSE
θ value	0 (rank : 2)	NC score	0.998639 (rank : 2)
Query Neighborhood Hits	47	Target Neighborhood Hits	45	Shared Neighborhood Hits	40
SwissProt Accessions	Q62448, P97867, Q921U3	Gene names	Eif4g2, Nat1
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 2 (eIF-4-gamma 2) (eIF-4G 2) (eIF4G 2) (p97) (Novel APOBEC-1 target 1) (Translation repressor NAT1).

IF4G3_HUMAN
θ value	3.04986e-48 (rank : 3)	NC score	0.762178 (rank : 3)
Query Neighborhood Hits	47	Target Neighborhood Hits	247	Shared Neighborhood Hits	13
SwissProt Accessions	O43432, Q15597, Q8NEN1	Gene names	EIF4G3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

IF4G3_MOUSE
θ value	5.20228e-48 (rank : 4)	NC score	0.757955 (rank : 4)
Query Neighborhood Hits	47	Target Neighborhood Hits	279	Shared Neighborhood Hits	15
SwissProt Accessions	Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0	Gene names	Eif4g3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

IF4G1_HUMAN
θ value	1.19932e-44 (rank : 5)	NC score	0.730470 (rank : 5)
Query Neighborhood Hits	47	Target Neighborhood Hits	347	Shared Neighborhood Hits	18
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

IF4G1_MOUSE
θ value	2.04573e-44 (rank : 6)	NC score	0.714922 (rank : 6)
Query Neighborhood Hits	47	Target Neighborhood Hits	534	Shared Neighborhood Hits	22
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

EI2BE_HUMAN
θ value	0.00035302 (rank : 7)	NC score	0.266471 (rank : 10)
Query Neighborhood Hits	47	Target Neighborhood Hits	20	Shared Neighborhood Hits	8
SwissProt Accessions	Q13144, Q96D04	Gene names	EIF2B5, EIF2BE
Domain Architecture
Description	Translation initiation factor eIF-2B subunit epsilon (eIF-2B GDP-GTP exchange factor subunit epsilon).

PAIP1_MOUSE
θ value	0.00035302 (rank : 8)	NC score	0.395498 (rank : 7)
Query Neighborhood Hits	47	Target Neighborhood Hits	21	Shared Neighborhood Hits	10
SwissProt Accessions	Q8VE62, Q9WUC9	Gene names	Paip1
Domain Architecture
Description	Polyadenylate-binding protein-interacting protein 1 (Poly(A)-binding protein-interacting protein 1) (PABP-interacting protein 1) (PAIP-1).

EI2BE_MOUSE
θ value	0.000461057 (rank : 9)	NC score	0.277075 (rank : 9)
Query Neighborhood Hits	47	Target Neighborhood Hits	30	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CHW4, Q3TU39	Gene names	Eif2b5
Domain Architecture	No domain graphic available
Description	Translation initiation factor eIF-2B subunit epsilon (eIF-2B GDP-GTP exchange factor subunit epsilon).

PAIP1_HUMAN
θ value	0.00102713 (rank : 10)	NC score	0.381263 (rank : 8)
Query Neighborhood Hits	47	Target Neighborhood Hits	76	Shared Neighborhood Hits	10
SwissProt Accessions	Q9H074, O60455, Q96B61, Q9BS63	Gene names	PAIP1
Domain Architecture
Description	Polyadenylate-binding protein-interacting protein 1 (Poly(A)-binding protein-interacting protein 1) (PABP-interacting protein 1) (PAIP-1).

K0427_MOUSE
θ value	0.00390308 (rank : 11)	NC score	0.253644 (rank : 12)
Query Neighborhood Hits	47	Target Neighborhood Hits	106	Shared Neighborhood Hits	11
SwissProt Accessions	Q6PEE2	Gene names	Gm672
Domain Architecture	No domain graphic available
Description	Protein KIAA0427 homolog.

K0427_HUMAN
θ value	0.0113563 (rank : 12)	NC score	0.258430 (rank : 11)
Query Neighborhood Hits	47	Target Neighborhood Hits	55	Shared Neighborhood Hits	11
SwissProt Accessions	O43310, Q8IVD5	Gene names	KIAA0427
Domain Architecture	No domain graphic available
Description	Protein KIAA0427.

ELK4_HUMAN
θ value	0.125558 (rank : 13)	NC score	0.039802 (rank : 18)
Query Neighborhood Hits	47	Target Neighborhood Hits	184	Shared Neighborhood Hits	6
SwissProt Accessions	P28324, P28323	Gene names	ELK4, SAP1
Domain Architecture
Description	ETS domain-containing protein Elk-4 (Serum response factor accessory protein 1) (SAP-1).

IL16_MOUSE
θ value	1.81305 (rank : 14)	NC score	0.027383 (rank : 23)
Query Neighborhood Hits	47	Target Neighborhood Hits	189	Shared Neighborhood Hits	3
SwissProt Accessions	O54824, O70236, Q3TEM4, Q8R0G5	Gene names	Il16
Domain Architecture	No domain graphic available
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

CSPG2_MOUSE
θ value	2.36792 (rank : 15)	NC score	0.014624 (rank : 37)
Query Neighborhood Hits	47	Target Neighborhood Hits	711	Shared Neighborhood Hits	6
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

PEX5_MOUSE
θ value	2.36792 (rank : 16)	NC score	0.028296 (rank : 22)
Query Neighborhood Hits	47	Target Neighborhood Hits	89	Shared Neighborhood Hits	3
SwissProt Accessions	O09012	Gene names	Pex5, Pxr1
Domain Architecture
Description	Peroxisomal targeting signal 1 receptor (Peroxisome receptor 1) (Peroxisomal C-terminal targeting signal import receptor) (PTS1-BP) (Peroxin-5) (PTS1 receptor) (PXR1P) (PTS1R).

REST_MOUSE
θ value	2.36792 (rank : 17)	NC score	0.006423 (rank : 46)
Query Neighborhood Hits	47	Target Neighborhood Hits	1506	Shared Neighborhood Hits	9
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

KPB1_MOUSE
θ value	3.0926 (rank : 18)	NC score	0.022632 (rank : 32)
Query Neighborhood Hits	47	Target Neighborhood Hits	24	Shared Neighborhood Hits	4
SwissProt Accessions	P18826	Gene names	Phka1
Domain Architecture
Description	Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform (Phosphorylase kinase alpha M subunit).

MEF2D_HUMAN
θ value	3.0926 (rank : 19)	NC score	0.031392 (rank : 21)
Query Neighborhood Hits	47	Target Neighborhood Hits	170	Shared Neighborhood Hits	8
SwissProt Accessions	Q14814, Q14815	Gene names	MEF2D
Domain Architecture
Description	Myocyte-specific enhancer factor 2D.

MEF2D_MOUSE
θ value	3.0926 (rank : 20)	NC score	0.034855 (rank : 19)
Query Neighborhood Hits	47	Target Neighborhood Hits	146	Shared Neighborhood Hits	8
SwissProt Accessions	Q63943, Q63944	Gene names	Mef2d
Domain Architecture
Description	Myocyte-specific enhancer factor 2D.

PRR12_HUMAN
θ value	3.0926 (rank : 21)	NC score	0.040703 (rank : 17)
Query Neighborhood Hits	47	Target Neighborhood Hits	460	Shared Neighborhood Hits	11
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

DCTN3_MOUSE
θ value	4.03905 (rank : 22)	NC score	0.045874 (rank : 16)
Query Neighborhood Hits	47	Target Neighborhood Hits	16	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z0Y1, Q9CR43, Q9D039	Gene names	Dctn3
Domain Architecture	No domain graphic available
Description	Dynactin subunit 3 (Dynactin light chain p24).

GLT12_MOUSE
θ value	4.03905 (rank : 23)	NC score	0.006011 (rank : 48)
Query Neighborhood Hits	47	Target Neighborhood Hits	51	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BGT9	Gene names	Galnt12
Domain Architecture	No domain graphic available
Description	Polypeptide N-acetylgalactosaminyltransferase 12 (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase 12) (UDP- GalNAc:polypeptide N-acetylgalactosaminyltransferase 12) (Polypeptide GalNAc transferase 12) (GalNAc-T12) (pp-GaNTase 12).

MYST3_HUMAN
θ value	4.03905 (rank : 24)	NC score	0.012965 (rank : 42)
Query Neighborhood Hits	47	Target Neighborhood Hits	772	Shared Neighborhood Hits	7
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

ADA12_MOUSE
θ value	5.27518 (rank : 25)	NC score	0.006826 (rank : 45)
Query Neighborhood Hits	47	Target Neighborhood Hits	474	Shared Neighborhood Hits	10
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

ADA15_HUMAN
θ value	5.27518 (rank : 26)	NC score	0.006335 (rank : 47)
Query Neighborhood Hits	47	Target Neighborhood Hits	288	Shared Neighborhood Hits	3
SwissProt Accessions	Q13444, Q13493, Q96C78	Gene names	ADAM15, MDC15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin).

BCL9_HUMAN
θ value	5.27518 (rank : 27)	NC score	0.046926 (rank : 15)
Query Neighborhood Hits	47	Target Neighborhood Hits	1008	Shared Neighborhood Hits	19
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

BRD4_MOUSE
θ value	5.27518 (rank : 28)	NC score	0.014211 (rank : 40)
Query Neighborhood Hits	47	Target Neighborhood Hits	845	Shared Neighborhood Hits	13
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

CBPE_MOUSE
θ value	5.27518 (rank : 29)	NC score	0.008081 (rank : 44)
Query Neighborhood Hits	47	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q00493, Q64439	Gene names	Cpe
Domain Architecture
Description	Carboxypeptidase E precursor (EC 3.4.17.10) (CPE) (Carboxypeptidase H) (CPH) (Enkephalin convertase) (Prohormone-processing carboxypeptidase).

CENPU_HUMAN
θ value	5.27518 (rank : 30)	NC score	0.025429 (rank : 26)
Query Neighborhood Hits	47	Target Neighborhood Hits	289	Shared Neighborhood Hits	6
SwissProt Accessions	Q71F23, Q32Q71, Q9H5G1	Gene names	MLF1IP, CENPU, ICEN24, KLIP1
Domain Architecture	No domain graphic available
Description	Centromere protein U (CENP-U) (CENP-U(50)) (CENP-50) (Interphase centromere complex protein 24) (MLF1-interacting protein) (KSHV latent nuclear antigen-interacting protein 1).

COPG2_HUMAN
θ value	5.27518 (rank : 31)	NC score	0.025939 (rank : 25)
Query Neighborhood Hits	47	Target Neighborhood Hits	33	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UBF2	Gene names	COPG2
Domain Architecture
Description	Coatomer subunit gamma-2 (Gamma-2 coat protein) (Gamma-2 COP).

EP400_MOUSE
θ value	5.27518 (rank : 32)	NC score	0.015708 (rank : 35)
Query Neighborhood Hits	47	Target Neighborhood Hits	592	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

GRIN1_MOUSE
θ value	5.27518 (rank : 33)	NC score	0.024835 (rank : 27)
Query Neighborhood Hits	47	Target Neighborhood Hits	337	Shared Neighborhood Hits	7
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

RC3H1_MOUSE
θ value	5.27518 (rank : 34)	NC score	0.014876 (rank : 36)
Query Neighborhood Hits	47	Target Neighborhood Hits	244	Shared Neighborhood Hits	4
SwissProt Accessions	Q4VGL6, Q69Z31	Gene names	Rc3h1, Gm551, Kiaa2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1) (Sanroque protein).

ANR26_MOUSE
θ value	6.88961 (rank : 35)	NC score	0.002481 (rank : 49)
Query Neighborhood Hits	47	Target Neighborhood Hits	1554	Shared Neighborhood Hits	7
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.

CIZ1_HUMAN
θ value	6.88961 (rank : 36)	NC score	0.023646 (rank : 29)
Query Neighborhood Hits	47	Target Neighborhood Hits	359	Shared Neighborhood Hits	12
SwissProt Accessions	Q9ULV3, Q9NYM8, Q9UHK4, Q9Y3F9, Q9Y3G0	Gene names	CIZ1, LSFR1, NP94
Domain Architecture	No domain graphic available
Description	Cip1-interacting zinc finger protein (Nuclear protein NP94).

COPG2_MOUSE
θ value	6.88961 (rank : 37)	NC score	0.023820 (rank : 28)
Query Neighborhood Hits	47	Target Neighborhood Hits	32	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QXK3	Gene names	Copg2
Domain Architecture
Description	Coatomer subunit gamma-2 (Gamma-2 coat protein) (Gamma-2 COP).

DEN1A_MOUSE
θ value	6.88961 (rank : 38)	NC score	0.022710 (rank : 31)
Query Neighborhood Hits	47	Target Neighborhood Hits	178	Shared Neighborhood Hits	7
SwissProt Accessions	Q8K382	Gene names	Dennd1a
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 1A.

GGN_HUMAN
θ value	6.88961 (rank : 39)	NC score	0.021471 (rank : 34)
Query Neighborhood Hits	47	Target Neighborhood Hits	269	Shared Neighborhood Hits	7
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

SC24C_HUMAN
θ value	6.88961 (rank : 40)	NC score	0.013988 (rank : 41)
Query Neighborhood Hits	47	Target Neighborhood Hits	662	Shared Neighborhood Hits	12
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

SFPQ_MOUSE
θ value	6.88961 (rank : 41)	NC score	0.023459 (rank : 30)
Query Neighborhood Hits	47	Target Neighborhood Hits	958	Shared Neighborhood Hits	13
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

CRTC1_HUMAN
θ value	8.99809 (rank : 42)	NC score	0.027197 (rank : 24)
Query Neighborhood Hits	47	Target Neighborhood Hits	319	Shared Neighborhood Hits	13
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

DCTN3_HUMAN
θ value	8.99809 (rank : 43)	NC score	0.033390 (rank : 20)
Query Neighborhood Hits	47	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	O75935, Q5T1I5, Q5T1I7, Q5T8G3, Q9BPU8	Gene names	DCTN3, DCNT22
Domain Architecture	No domain graphic available
Description	Dynactin subunit 3 (Dynactin complex subunit 22 kDa subunit) (p22).

DEN1A_HUMAN
θ value	8.99809 (rank : 44)	NC score	0.021488 (rank : 33)
Query Neighborhood Hits	47	Target Neighborhood Hits	176	Shared Neighborhood Hits	6
SwissProt Accessions	Q8TEH3, Q5VWF0, Q8IVD6, Q9H796	Gene names	DENND1A
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 1A.

HGS_HUMAN
θ value	8.99809 (rank : 45)	NC score	0.010438 (rank : 43)
Query Neighborhood Hits	47	Target Neighborhood Hits	517	Shared Neighborhood Hits	11
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

HNRL1_MOUSE
θ value	8.99809 (rank : 46)	NC score	0.014463 (rank : 38)
Query Neighborhood Hits	47	Target Neighborhood Hits	200	Shared Neighborhood Hits	7
SwissProt Accessions	Q8VDM6, Q3U201, Q3UPB0, Q6AZA7, Q8BY45, Q8K365	Gene names	Hnrpul1
Domain Architecture	No domain graphic available
Description	Heterogeneous nuclear ribonucleoprotein U-like protein 1.

KPB1_HUMAN
θ value	8.99809 (rank : 47)	NC score	0.014378 (rank : 39)
Query Neighborhood Hits	47	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	P46020, Q2M3D7	Gene names	PHKA1, PHKA
Domain Architecture
Description	Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform (Phosphorylase kinase alpha M subunit).

IF5_HUMAN
θ value	θ > 10 (rank : 48)	NC score	0.079568 (rank : 14)
Query Neighborhood Hits	47	Target Neighborhood Hits	36	Shared Neighborhood Hits	7
SwissProt Accessions	P55010, Q9H5N2, Q9UG48	Gene names	EIF5
Domain Architecture
Description	Eukaryotic translation initiation factor 5 (eIF-5).

IF5_MOUSE
θ value	θ > 10 (rank : 49)	NC score	0.080436 (rank : 13)
Query Neighborhood Hits	47	Target Neighborhood Hits	35	Shared Neighborhood Hits	7
SwissProt Accessions	P59325	Gene names	Eif5
Domain Architecture
Description	Eukaryotic translation initiation factor 5 (eIF-5).

Hits sorted by NC score

IF4G2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	47	Target Neighborhood Hits	47	Shared Neighborhood Hits	47
SwissProt Accessions	P78344, O60877, P78404, Q53EU1, Q58EZ2, Q8NI71, Q96C16	Gene names	EIF4G2, DAP5
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 2 (eIF-4-gamma 2) (eIF-4G 2) (eIF4G 2) (p97) (Death-associated protein 5) (DAP-5).

IF4G2_MOUSE
NC score	0.998639 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	47	Target Neighborhood Hits	45	Shared Neighborhood Hits	40
SwissProt Accessions	Q62448, P97867, Q921U3	Gene names	Eif4g2, Nat1
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 2 (eIF-4-gamma 2) (eIF-4G 2) (eIF4G 2) (p97) (Novel APOBEC-1 target 1) (Translation repressor NAT1).

IF4G3_HUMAN
NC score	0.762178 (rank : 3)	θ value	3.04986e-48 (rank : 3)
Query Neighborhood Hits	47	Target Neighborhood Hits	247	Shared Neighborhood Hits	13
SwissProt Accessions	O43432, Q15597, Q8NEN1	Gene names	EIF4G3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

IF4G3_MOUSE
NC score	0.757955 (rank : 4)	θ value	5.20228e-48 (rank : 4)
Query Neighborhood Hits	47	Target Neighborhood Hits	279	Shared Neighborhood Hits	15
SwissProt Accessions	Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0	Gene names	Eif4g3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

IF4G1_HUMAN
NC score	0.730470 (rank : 5)	θ value	1.19932e-44 (rank : 5)
Query Neighborhood Hits	47	Target Neighborhood Hits	347	Shared Neighborhood Hits	18
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

IF4G1_MOUSE
NC score	0.714922 (rank : 6)	θ value	2.04573e-44 (rank : 6)
Query Neighborhood Hits	47	Target Neighborhood Hits	534	Shared Neighborhood Hits	22
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

PAIP1_MOUSE
NC score	0.395498 (rank : 7)	θ value	0.00035302 (rank : 8)
Query Neighborhood Hits	47	Target Neighborhood Hits	21	Shared Neighborhood Hits	10
SwissProt Accessions	Q8VE62, Q9WUC9	Gene names	Paip1
Domain Architecture
Description	Polyadenylate-binding protein-interacting protein 1 (Poly(A)-binding protein-interacting protein 1) (PABP-interacting protein 1) (PAIP-1).

PAIP1_HUMAN
NC score	0.381263 (rank : 8)	θ value	0.00102713 (rank : 10)
Query Neighborhood Hits	47	Target Neighborhood Hits	76	Shared Neighborhood Hits	10
SwissProt Accessions	Q9H074, O60455, Q96B61, Q9BS63	Gene names	PAIP1
Domain Architecture
Description	Polyadenylate-binding protein-interacting protein 1 (Poly(A)-binding protein-interacting protein 1) (PABP-interacting protein 1) (PAIP-1).

EI2BE_MOUSE
NC score	0.277075 (rank : 9)	θ value	0.000461057 (rank : 9)
Query Neighborhood Hits	47	Target Neighborhood Hits	30	Shared Neighborhood Hits	8
SwissProt Accessions	Q8CHW4, Q3TU39	Gene names	Eif2b5
Domain Architecture	No domain graphic available
Description	Translation initiation factor eIF-2B subunit epsilon (eIF-2B GDP-GTP exchange factor subunit epsilon).

EI2BE_HUMAN
NC score	0.266471 (rank : 10)	θ value	0.00035302 (rank : 7)
Query Neighborhood Hits	47	Target Neighborhood Hits	20	Shared Neighborhood Hits	8
SwissProt Accessions	Q13144, Q96D04	Gene names	EIF2B5, EIF2BE
Domain Architecture
Description	Translation initiation factor eIF-2B subunit epsilon (eIF-2B GDP-GTP exchange factor subunit epsilon).

K0427_HUMAN
NC score	0.258430 (rank : 11)	θ value	0.0113563 (rank : 12)
Query Neighborhood Hits	47	Target Neighborhood Hits	55	Shared Neighborhood Hits	11
SwissProt Accessions	O43310, Q8IVD5	Gene names	KIAA0427
Domain Architecture	No domain graphic available
Description	Protein KIAA0427.

K0427_MOUSE
NC score	0.253644 (rank : 12)	θ value	0.00390308 (rank : 11)
Query Neighborhood Hits	47	Target Neighborhood Hits	106	Shared Neighborhood Hits	11
SwissProt Accessions	Q6PEE2	Gene names	Gm672
Domain Architecture	No domain graphic available
Description	Protein KIAA0427 homolog.

IF5_MOUSE
NC score	0.080436 (rank : 13)	θ value	θ > 10 (rank : 49)
Query Neighborhood Hits	47	Target Neighborhood Hits	35	Shared Neighborhood Hits	7
SwissProt Accessions	P59325	Gene names	Eif5
Domain Architecture
Description	Eukaryotic translation initiation factor 5 (eIF-5).

IF5_HUMAN
NC score	0.079568 (rank : 14)	θ value	θ > 10 (rank : 48)
Query Neighborhood Hits	47	Target Neighborhood Hits	36	Shared Neighborhood Hits	7
SwissProt Accessions	P55010, Q9H5N2, Q9UG48	Gene names	EIF5
Domain Architecture
Description	Eukaryotic translation initiation factor 5 (eIF-5).

BCL9_HUMAN
NC score	0.046926 (rank : 15)	θ value	5.27518 (rank : 27)
Query Neighborhood Hits	47	Target Neighborhood Hits	1008	Shared Neighborhood Hits	19
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

DCTN3_MOUSE
NC score	0.045874 (rank : 16)	θ value	4.03905 (rank : 22)
Query Neighborhood Hits	47	Target Neighborhood Hits	16	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z0Y1, Q9CR43, Q9D039	Gene names	Dctn3
Domain Architecture	No domain graphic available
Description	Dynactin subunit 3 (Dynactin light chain p24).

PRR12_HUMAN
NC score	0.040703 (rank : 17)	θ value	3.0926 (rank : 21)
Query Neighborhood Hits	47	Target Neighborhood Hits	460	Shared Neighborhood Hits	11
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

ELK4_HUMAN
NC score	0.039802 (rank : 18)	θ value	0.125558 (rank : 13)
Query Neighborhood Hits	47	Target Neighborhood Hits	184	Shared Neighborhood Hits	6
SwissProt Accessions	P28324, P28323	Gene names	ELK4, SAP1
Domain Architecture
Description	ETS domain-containing protein Elk-4 (Serum response factor accessory protein 1) (SAP-1).

MEF2D_MOUSE
NC score	0.034855 (rank : 19)	θ value	3.0926 (rank : 20)
Query Neighborhood Hits	47	Target Neighborhood Hits	146	Shared Neighborhood Hits	8
SwissProt Accessions	Q63943, Q63944	Gene names	Mef2d
Domain Architecture
Description	Myocyte-specific enhancer factor 2D.

DCTN3_HUMAN
NC score	0.033390 (rank : 20)	θ value	8.99809 (rank : 43)
Query Neighborhood Hits	47	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	O75935, Q5T1I5, Q5T1I7, Q5T8G3, Q9BPU8	Gene names	DCTN3, DCNT22
Domain Architecture	No domain graphic available
Description	Dynactin subunit 3 (Dynactin complex subunit 22 kDa subunit) (p22).

MEF2D_HUMAN
NC score	0.031392 (rank : 21)	θ value	3.0926 (rank : 19)
Query Neighborhood Hits	47	Target Neighborhood Hits	170	Shared Neighborhood Hits	8
SwissProt Accessions	Q14814, Q14815	Gene names	MEF2D
Domain Architecture
Description	Myocyte-specific enhancer factor 2D.

PEX5_MOUSE
NC score	0.028296 (rank : 22)	θ value	2.36792 (rank : 16)
Query Neighborhood Hits	47	Target Neighborhood Hits	89	Shared Neighborhood Hits	3
SwissProt Accessions	O09012	Gene names	Pex5, Pxr1
Domain Architecture
Description	Peroxisomal targeting signal 1 receptor (Peroxisome receptor 1) (Peroxisomal C-terminal targeting signal import receptor) (PTS1-BP) (Peroxin-5) (PTS1 receptor) (PXR1P) (PTS1R).

IL16_MOUSE
NC score	0.027383 (rank : 23)	θ value	1.81305 (rank : 14)
Query Neighborhood Hits	47	Target Neighborhood Hits	189	Shared Neighborhood Hits	3
SwissProt Accessions	O54824, O70236, Q3TEM4, Q8R0G5	Gene names	Il16
Domain Architecture	No domain graphic available
Description	Interleukin-16 precursor (IL-16) (Lymphocyte chemoattractant factor) (LCF).

CRTC1_HUMAN
NC score	0.027197 (rank : 24)	θ value	8.99809 (rank : 42)
Query Neighborhood Hits	47	Target Neighborhood Hits	319	Shared Neighborhood Hits	13
SwissProt Accessions	Q6UUV9, O75114, Q6Y3A3, Q7LDZ2, Q8IUL3, Q8IZ34, Q8IZL1, Q8N6W3, Q96AI8, Q9H801	Gene names	CRTC1, KIAA0616, MECT1, TORC1, WAMTP1
Domain Architecture	No domain graphic available
Description	CREB-regulated transcription coactivator 1 (Transducer of regulated cAMP response element-binding protein 1) (Transducer of CREB protein 1) (Mucoepidermoid carcinoma translocated protein 1).

COPG2_HUMAN
NC score	0.025939 (rank : 25)	θ value	5.27518 (rank : 31)
Query Neighborhood Hits	47	Target Neighborhood Hits	33	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UBF2	Gene names	COPG2
Domain Architecture
Description	Coatomer subunit gamma-2 (Gamma-2 coat protein) (Gamma-2 COP).

CENPU_HUMAN
NC score	0.025429 (rank : 26)	θ value	5.27518 (rank : 30)
Query Neighborhood Hits	47	Target Neighborhood Hits	289	Shared Neighborhood Hits	6
SwissProt Accessions	Q71F23, Q32Q71, Q9H5G1	Gene names	MLF1IP, CENPU, ICEN24, KLIP1
Domain Architecture	No domain graphic available
Description	Centromere protein U (CENP-U) (CENP-U(50)) (CENP-50) (Interphase centromere complex protein 24) (MLF1-interacting protein) (KSHV latent nuclear antigen-interacting protein 1).

GRIN1_MOUSE
NC score	0.024835 (rank : 27)	θ value	5.27518 (rank : 33)
Query Neighborhood Hits	47	Target Neighborhood Hits	337	Shared Neighborhood Hits	7
SwissProt Accessions	Q3UNH4, Q6PGF9, Q9QZY2	Gene names	Gprin1
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

COPG2_MOUSE
NC score	0.023820 (rank : 28)	θ value	6.88961 (rank : 37)
Query Neighborhood Hits	47	Target Neighborhood Hits	32	Shared Neighborhood Hits	4
SwissProt Accessions	Q9QXK3	Gene names	Copg2
Domain Architecture
Description	Coatomer subunit gamma-2 (Gamma-2 coat protein) (Gamma-2 COP).

CIZ1_HUMAN
NC score	0.023646 (rank : 29)	θ value	6.88961 (rank : 36)
Query Neighborhood Hits	47	Target Neighborhood Hits	359	Shared Neighborhood Hits	12
SwissProt Accessions	Q9ULV3, Q9NYM8, Q9UHK4, Q9Y3F9, Q9Y3G0	Gene names	CIZ1, LSFR1, NP94
Domain Architecture	No domain graphic available
Description	Cip1-interacting zinc finger protein (Nuclear protein NP94).

SFPQ_MOUSE
NC score	0.023459 (rank : 30)	θ value	6.88961 (rank : 41)
Query Neighborhood Hits	47	Target Neighborhood Hits	958	Shared Neighborhood Hits	13
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

DEN1A_MOUSE
NC score	0.022710 (rank : 31)	θ value	6.88961 (rank : 38)
Query Neighborhood Hits	47	Target Neighborhood Hits	178	Shared Neighborhood Hits	7
SwissProt Accessions	Q8K382	Gene names	Dennd1a
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 1A.

KPB1_MOUSE
NC score	0.022632 (rank : 32)	θ value	3.0926 (rank : 18)
Query Neighborhood Hits	47	Target Neighborhood Hits	24	Shared Neighborhood Hits	4
SwissProt Accessions	P18826	Gene names	Phka1
Domain Architecture
Description	Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform (Phosphorylase kinase alpha M subunit).

DEN1A_HUMAN
NC score	0.021488 (rank : 33)	θ value	8.99809 (rank : 44)
Query Neighborhood Hits	47	Target Neighborhood Hits	176	Shared Neighborhood Hits	6
SwissProt Accessions	Q8TEH3, Q5VWF0, Q8IVD6, Q9H796	Gene names	DENND1A
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 1A.

GGN_HUMAN
NC score	0.021471 (rank : 34)	θ value	6.88961 (rank : 39)
Query Neighborhood Hits	47	Target Neighborhood Hits	269	Shared Neighborhood Hits	7
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

EP400_MOUSE
NC score	0.015708 (rank : 35)	θ value	5.27518 (rank : 32)
Query Neighborhood Hits	47	Target Neighborhood Hits	592	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

RC3H1_MOUSE
NC score	0.014876 (rank : 36)	θ value	5.27518 (rank : 34)
Query Neighborhood Hits	47	Target Neighborhood Hits	244	Shared Neighborhood Hits	4
SwissProt Accessions	Q4VGL6, Q69Z31	Gene names	Rc3h1, Gm551, Kiaa2025
Domain Architecture	No domain graphic available
Description	Roquin (RING finger and C3H zinc finger protein 1) (Sanroque protein).

CSPG2_MOUSE
NC score	0.014624 (rank : 37)	θ value	2.36792 (rank : 15)
Query Neighborhood Hits	47	Target Neighborhood Hits	711	Shared Neighborhood Hits	6
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

HNRL1_MOUSE
NC score	0.014463 (rank : 38)	θ value	8.99809 (rank : 46)
Query Neighborhood Hits	47	Target Neighborhood Hits	200	Shared Neighborhood Hits	7
SwissProt Accessions	Q8VDM6, Q3U201, Q3UPB0, Q6AZA7, Q8BY45, Q8K365	Gene names	Hnrpul1
Domain Architecture	No domain graphic available
Description	Heterogeneous nuclear ribonucleoprotein U-like protein 1.

KPB1_HUMAN
NC score	0.014378 (rank : 39)	θ value	8.99809 (rank : 47)
Query Neighborhood Hits	47	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	P46020, Q2M3D7	Gene names	PHKA1, PHKA
Domain Architecture
Description	Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform (Phosphorylase kinase alpha M subunit).

BRD4_MOUSE
NC score	0.014211 (rank : 40)	θ value	5.27518 (rank : 28)
Query Neighborhood Hits	47	Target Neighborhood Hits	845	Shared Neighborhood Hits	13
SwissProt Accessions	Q9ESU6, Q8VHF7, Q8VHF8	Gene names	Brd4, Mcap
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 4 (Mitotic chromosome-associated protein) (MCAP).

SC24C_HUMAN
NC score	0.013988 (rank : 41)	θ value	6.88961 (rank : 40)
Query Neighborhood Hits	47	Target Neighborhood Hits	662	Shared Neighborhood Hits	12
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

MYST3_HUMAN
NC score	0.012965 (rank : 42)	θ value	4.03905 (rank : 24)
Query Neighborhood Hits	47	Target Neighborhood Hits	772	Shared Neighborhood Hits	7
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

HGS_HUMAN
NC score	0.010438 (rank : 43)	θ value	8.99809 (rank : 45)
Query Neighborhood Hits	47	Target Neighborhood Hits	517	Shared Neighborhood Hits	11
SwissProt Accessions	O14964, Q9NR36	Gene names	HGS, HRS
Domain Architecture	No domain graphic available
Description	Hepatocyte growth factor-regulated tyrosine kinase substrate (Protein pp110) (Hrs).

CBPE_MOUSE
NC score	0.008081 (rank : 44)	θ value	5.27518 (rank : 29)
Query Neighborhood Hits	47	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	Q00493, Q64439	Gene names	Cpe
Domain Architecture
Description	Carboxypeptidase E precursor (EC 3.4.17.10) (CPE) (Carboxypeptidase H) (CPH) (Enkephalin convertase) (Prohormone-processing carboxypeptidase).

ADA12_MOUSE
NC score	0.006826 (rank : 45)	θ value	5.27518 (rank : 25)
Query Neighborhood Hits	47	Target Neighborhood Hits	474	Shared Neighborhood Hits	10
SwissProt Accessions	Q61824	Gene names	Adam12, Mltna
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

REST_MOUSE
NC score	0.006423 (rank : 46)	θ value	2.36792 (rank : 17)
Query Neighborhood Hits	47	Target Neighborhood Hits	1506	Shared Neighborhood Hits	9
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

ADA15_HUMAN
NC score	0.006335 (rank : 47)	θ value	5.27518 (rank : 26)
Query Neighborhood Hits	47	Target Neighborhood Hits	288	Shared Neighborhood Hits	3
SwissProt Accessions	Q13444, Q13493, Q96C78	Gene names	ADAM15, MDC15
Domain Architecture
Description	ADAM 15 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 15) (Metalloproteinase-like, disintegrin-like, and cysteine- rich protein 15) (MDC-15) (Metalloprotease RGD disintegrin protein) (Metargidin).

GLT12_MOUSE
NC score	0.006011 (rank : 48)	θ value	4.03905 (rank : 23)
Query Neighborhood Hits	47	Target Neighborhood Hits	51	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BGT9	Gene names	Galnt12
Domain Architecture	No domain graphic available
Description	Polypeptide N-acetylgalactosaminyltransferase 12 (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase 12) (UDP- GalNAc:polypeptide N-acetylgalactosaminyltransferase 12) (Polypeptide GalNAc transferase 12) (GalNAc-T12) (pp-GaNTase 12).

ANR26_MOUSE
NC score	0.002481 (rank : 49)	θ value	6.88961 (rank : 35)
Query Neighborhood Hits	47	Target Neighborhood Hits	1554	Shared Neighborhood Hits	7
SwissProt Accessions	Q811D2, Q69ZS2, Q9CS61	Gene names	Ankrd26, Kiaa1074
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 26.