Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : EI2BE_HUMAN

For an explanation of this page, click here

EI2BE_HUMAN
SwissProt Accessions	Q13144, Q96D04	Gene names	EIF2B5, EIF2BE
Domain Architecture
Description	Translation initiation factor eIF-2B subunit epsilon (eIF-2B GDP-GTP exchange factor subunit epsilon).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

EI2BE_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	20	Target Neighborhood Hits	20	Shared Neighborhood Hits	20
SwissProt Accessions	Q13144, Q96D04	Gene names	EIF2B5, EIF2BE
Domain Architecture
Description	Translation initiation factor eIF-2B subunit epsilon (eIF-2B GDP-GTP exchange factor subunit epsilon).

EI2BE_MOUSE
θ value	0 (rank : 2)	NC score	0.995515 (rank : 2)
Query Neighborhood Hits	20	Target Neighborhood Hits	30	Shared Neighborhood Hits	13
SwissProt Accessions	Q8CHW4, Q3TU39	Gene names	Eif2b5
Domain Architecture	No domain graphic available
Description	Translation initiation factor eIF-2B subunit epsilon (eIF-2B GDP-GTP exchange factor subunit epsilon).

EI2BG_HUMAN
θ value	2.21117e-06 (rank : 3)	NC score	0.356554 (rank : 3)
Query Neighborhood Hits	20	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NR50, Q5QP89, Q5QP90, Q8NDB5, Q8WV57, Q9H850	Gene names	EIF2B3
Domain Architecture
Description	Translation initiation factor eIF-2B subunit gamma (eIF-2B GDP-GTP exchange factor subunit gamma).

IF5_HUMAN
θ value	0.00020696 (rank : 4)	NC score	0.268577 (rank : 6)
Query Neighborhood Hits	20	Target Neighborhood Hits	36	Shared Neighborhood Hits	9
SwissProt Accessions	P55010, Q9H5N2, Q9UG48	Gene names	EIF5
Domain Architecture
Description	Eukaryotic translation initiation factor 5 (eIF-5).

IF5_MOUSE
θ value	0.00020696 (rank : 5)	NC score	0.269304 (rank : 4)
Query Neighborhood Hits	20	Target Neighborhood Hits	35	Shared Neighborhood Hits	9
SwissProt Accessions	P59325	Gene names	Eif5
Domain Architecture
Description	Eukaryotic translation initiation factor 5 (eIF-5).

IF4G2_MOUSE
θ value	0.000270298 (rank : 6)	NC score	0.269298 (rank : 5)
Query Neighborhood Hits	20	Target Neighborhood Hits	45	Shared Neighborhood Hits	10
SwissProt Accessions	Q62448, P97867, Q921U3	Gene names	Eif4g2, Nat1
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 2 (eIF-4-gamma 2) (eIF-4G 2) (eIF4G 2) (p97) (Novel APOBEC-1 target 1) (Translation repressor NAT1).

IF4G2_HUMAN
θ value	0.00035302 (rank : 7)	NC score	0.266471 (rank : 7)
Query Neighborhood Hits	20	Target Neighborhood Hits	47	Shared Neighborhood Hits	8
SwissProt Accessions	P78344, O60877, P78404, Q53EU1, Q58EZ2, Q8NI71, Q96C16	Gene names	EIF4G2, DAP5
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 2 (eIF-4-gamma 2) (eIF-4G 2) (eIF4G 2) (p97) (Death-associated protein 5) (DAP-5).

IF4G1_HUMAN
θ value	0.000461057 (rank : 8)	NC score	0.237331 (rank : 8)
Query Neighborhood Hits	20	Target Neighborhood Hits	347	Shared Neighborhood Hits	10
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

IF4G1_MOUSE
θ value	0.00102713 (rank : 9)	NC score	0.225935 (rank : 11)
Query Neighborhood Hits	20	Target Neighborhood Hits	534	Shared Neighborhood Hits	10
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

IF4G3_HUMAN
θ value	0.00509761 (rank : 10)	NC score	0.230791 (rank : 9)
Query Neighborhood Hits	20	Target Neighborhood Hits	247	Shared Neighborhood Hits	11
SwissProt Accessions	O43432, Q15597, Q8NEN1	Gene names	EIF4G3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

IF4G3_MOUSE
θ value	0.00509761 (rank : 11)	NC score	0.229958 (rank : 10)
Query Neighborhood Hits	20	Target Neighborhood Hits	279	Shared Neighborhood Hits	11
SwissProt Accessions	Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0	Gene names	Eif4g3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

ICA69_MOUSE
θ value	5.27518 (rank : 12)	NC score	0.017200 (rank : 16)
Query Neighborhood Hits	20	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	P97411, P97362, P97954, Q99M40, Q9R2C4	Gene names	Ica1, Icap69
Domain Architecture	No domain graphic available
Description	Islet cell autoantigen 1 (69 kDa islet cell autoantigen) (ICA69) (p69) (Islet cell autoantigen p69) (ICAp69).

LRRC7_HUMAN
θ value	5.27518 (rank : 13)	NC score	0.006372 (rank : 21)
Query Neighborhood Hits	20	Target Neighborhood Hits	423	Shared Neighborhood Hits	2
SwissProt Accessions	Q96NW7, Q5VXC2, Q5VXC3, Q68D07, Q86VE8, Q8WX20, Q9P2I2	Gene names	LRRC7, KIAA1365, LAP1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

IL33_MOUSE
θ value	6.88961 (rank : 14)	NC score	0.035504 (rank : 14)
Query Neighborhood Hits	20	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BVZ5, Q2YEJ4, Q3TQN0, Q99L46	Gene names	Il33
Domain Architecture	No domain graphic available
Description	Interleukin-33 precursor (IL-33).

KAZD1_MOUSE
θ value	6.88961 (rank : 15)	NC score	0.020322 (rank : 15)
Query Neighborhood Hits	20	Target Neighborhood Hits	281	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BJ66	Gene names	Kazald1, Bono1, Igfbprp10
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor (IGFBP-related protein 10) (IGFBP-rP10) (Bone and odontoblast expressed protein 1).

JIP1_HUMAN
θ value	8.99809 (rank : 16)	NC score	0.015649 (rank : 17)
Query Neighborhood Hits	20	Target Neighborhood Hits	271	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

JIP1_MOUSE
θ value	8.99809 (rank : 17)	NC score	0.015638 (rank : 18)
Query Neighborhood Hits	20	Target Neighborhood Hits	259	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WVI9, O35145, Q925J8, Q9R1H9, Q9R1Z1, Q9WVI7, Q9WVI8	Gene names	Mapk8ip1, Ib1, Jip1, Mapk8ip, Prkm8ip
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain-1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

NF2L2_HUMAN
θ value	8.99809 (rank : 18)	NC score	0.010270 (rank : 19)
Query Neighborhood Hits	20	Target Neighborhood Hits	109	Shared Neighborhood Hits	2
SwissProt Accessions	Q16236, Q96F71	Gene names	NFE2L2, NRF2
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 2 (NF-E2-related factor 2) (NFE2-related factor 2) (Nuclear factor, erythroid derived 2, like 2) (HEBP1).

TRHY_HUMAN
θ value	8.99809 (rank : 19)	NC score	0.002842 (rank : 22)
Query Neighborhood Hits	20	Target Neighborhood Hits	1385	Shared Neighborhood Hits	4
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

UT14A_MOUSE
θ value	8.99809 (rank : 20)	NC score	0.009725 (rank : 20)
Query Neighborhood Hits	20	Target Neighborhood Hits	177	Shared Neighborhood Hits	2
SwissProt Accessions	Q640M1, Q6A094, Q6EJB4, Q6P6L1, Q9CZK8	Gene names	Utp14a, JsdX, Kiaa0266
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 14 homolog A (Juvenile spermatogonial depletion-like X-linked protein) (Jsd-like X-linked protein).

PAIP1_HUMAN
θ value	θ > 10 (rank : 21)	NC score	0.064266 (rank : 13)
Query Neighborhood Hits	20	Target Neighborhood Hits	76	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H074, O60455, Q96B61, Q9BS63	Gene names	PAIP1
Domain Architecture
Description	Polyadenylate-binding protein-interacting protein 1 (Poly(A)-binding protein-interacting protein 1) (PABP-interacting protein 1) (PAIP-1).

PAIP1_MOUSE
θ value	θ > 10 (rank : 22)	NC score	0.066577 (rank : 12)
Query Neighborhood Hits	20	Target Neighborhood Hits	21	Shared Neighborhood Hits	6
SwissProt Accessions	Q8VE62, Q9WUC9	Gene names	Paip1
Domain Architecture
Description	Polyadenylate-binding protein-interacting protein 1 (Poly(A)-binding protein-interacting protein 1) (PABP-interacting protein 1) (PAIP-1).

Hits sorted by NC score

EI2BE_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	20	Target Neighborhood Hits	20	Shared Neighborhood Hits	20
SwissProt Accessions	Q13144, Q96D04	Gene names	EIF2B5, EIF2BE
Domain Architecture
Description	Translation initiation factor eIF-2B subunit epsilon (eIF-2B GDP-GTP exchange factor subunit epsilon).

EI2BE_MOUSE
NC score	0.995515 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	20	Target Neighborhood Hits	30	Shared Neighborhood Hits	13
SwissProt Accessions	Q8CHW4, Q3TU39	Gene names	Eif2b5
Domain Architecture	No domain graphic available
Description	Translation initiation factor eIF-2B subunit epsilon (eIF-2B GDP-GTP exchange factor subunit epsilon).

EI2BG_HUMAN
NC score	0.356554 (rank : 3)	θ value	2.21117e-06 (rank : 3)
Query Neighborhood Hits	20	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NR50, Q5QP89, Q5QP90, Q8NDB5, Q8WV57, Q9H850	Gene names	EIF2B3
Domain Architecture
Description	Translation initiation factor eIF-2B subunit gamma (eIF-2B GDP-GTP exchange factor subunit gamma).

IF5_MOUSE
NC score	0.269304 (rank : 4)	θ value	0.00020696 (rank : 5)
Query Neighborhood Hits	20	Target Neighborhood Hits	35	Shared Neighborhood Hits	9
SwissProt Accessions	P59325	Gene names	Eif5
Domain Architecture
Description	Eukaryotic translation initiation factor 5 (eIF-5).

IF4G2_MOUSE
NC score	0.269298 (rank : 5)	θ value	0.000270298 (rank : 6)
Query Neighborhood Hits	20	Target Neighborhood Hits	45	Shared Neighborhood Hits	10
SwissProt Accessions	Q62448, P97867, Q921U3	Gene names	Eif4g2, Nat1
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 2 (eIF-4-gamma 2) (eIF-4G 2) (eIF4G 2) (p97) (Novel APOBEC-1 target 1) (Translation repressor NAT1).

IF5_HUMAN
NC score	0.268577 (rank : 6)	θ value	0.00020696 (rank : 4)
Query Neighborhood Hits	20	Target Neighborhood Hits	36	Shared Neighborhood Hits	9
SwissProt Accessions	P55010, Q9H5N2, Q9UG48	Gene names	EIF5
Domain Architecture
Description	Eukaryotic translation initiation factor 5 (eIF-5).

IF4G2_HUMAN
NC score	0.266471 (rank : 7)	θ value	0.00035302 (rank : 7)
Query Neighborhood Hits	20	Target Neighborhood Hits	47	Shared Neighborhood Hits	8
SwissProt Accessions	P78344, O60877, P78404, Q53EU1, Q58EZ2, Q8NI71, Q96C16	Gene names	EIF4G2, DAP5
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 2 (eIF-4-gamma 2) (eIF-4G 2) (eIF4G 2) (p97) (Death-associated protein 5) (DAP-5).

IF4G1_HUMAN
NC score	0.237331 (rank : 8)	θ value	0.000461057 (rank : 8)
Query Neighborhood Hits	20	Target Neighborhood Hits	347	Shared Neighborhood Hits	10
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

IF4G3_HUMAN
NC score	0.230791 (rank : 9)	θ value	0.00509761 (rank : 10)
Query Neighborhood Hits	20	Target Neighborhood Hits	247	Shared Neighborhood Hits	11
SwissProt Accessions	O43432, Q15597, Q8NEN1	Gene names	EIF4G3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

IF4G3_MOUSE
NC score	0.229958 (rank : 10)	θ value	0.00509761 (rank : 11)
Query Neighborhood Hits	20	Target Neighborhood Hits	279	Shared Neighborhood Hits	11
SwissProt Accessions	Q80XI3, Q80Y69, Q8BJ68, Q8BQF3, Q8C6Q3, Q8CIH0	Gene names	Eif4g3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

IF4G1_MOUSE
NC score	0.225935 (rank : 11)	θ value	0.00102713 (rank : 9)
Query Neighborhood Hits	20	Target Neighborhood Hits	534	Shared Neighborhood Hits	10
SwissProt Accessions	Q6NZJ6, Q6NZN8, Q8BW99	Gene names	Eif4g1
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1).

PAIP1_MOUSE
NC score	0.066577 (rank : 12)	θ value	θ > 10 (rank : 22)
Query Neighborhood Hits	20	Target Neighborhood Hits	21	Shared Neighborhood Hits	6
SwissProt Accessions	Q8VE62, Q9WUC9	Gene names	Paip1
Domain Architecture
Description	Polyadenylate-binding protein-interacting protein 1 (Poly(A)-binding protein-interacting protein 1) (PABP-interacting protein 1) (PAIP-1).

PAIP1_HUMAN
NC score	0.064266 (rank : 13)	θ value	θ > 10 (rank : 21)
Query Neighborhood Hits	20	Target Neighborhood Hits	76	Shared Neighborhood Hits	6
SwissProt Accessions	Q9H074, O60455, Q96B61, Q9BS63	Gene names	PAIP1
Domain Architecture
Description	Polyadenylate-binding protein-interacting protein 1 (Poly(A)-binding protein-interacting protein 1) (PABP-interacting protein 1) (PAIP-1).

IL33_MOUSE
NC score	0.035504 (rank : 14)	θ value	6.88961 (rank : 14)
Query Neighborhood Hits	20	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BVZ5, Q2YEJ4, Q3TQN0, Q99L46	Gene names	Il33
Domain Architecture	No domain graphic available
Description	Interleukin-33 precursor (IL-33).

KAZD1_MOUSE
NC score	0.020322 (rank : 15)	θ value	6.88961 (rank : 15)
Query Neighborhood Hits	20	Target Neighborhood Hits	281	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BJ66	Gene names	Kazald1, Bono1, Igfbprp10
Domain Architecture	No domain graphic available
Description	Kazal-type serine protease inhibitor domain-containing protein 1 precursor (IGFBP-related protein 10) (IGFBP-rP10) (Bone and odontoblast expressed protein 1).

ICA69_MOUSE
NC score	0.017200 (rank : 16)	θ value	5.27518 (rank : 12)
Query Neighborhood Hits	20	Target Neighborhood Hits	27	Shared Neighborhood Hits	2
SwissProt Accessions	P97411, P97362, P97954, Q99M40, Q9R2C4	Gene names	Ica1, Icap69
Domain Architecture	No domain graphic available
Description	Islet cell autoantigen 1 (69 kDa islet cell autoantigen) (ICA69) (p69) (Islet cell autoantigen p69) (ICAp69).

JIP1_HUMAN
NC score	0.015649 (rank : 17)	θ value	8.99809 (rank : 16)
Query Neighborhood Hits	20	Target Neighborhood Hits	271	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UQF2, O43407	Gene names	MAPK8IP1, IB1, JIP1
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain 1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

JIP1_MOUSE
NC score	0.015638 (rank : 18)	θ value	8.99809 (rank : 17)
Query Neighborhood Hits	20	Target Neighborhood Hits	259	Shared Neighborhood Hits	3
SwissProt Accessions	Q9WVI9, O35145, Q925J8, Q9R1H9, Q9R1Z1, Q9WVI7, Q9WVI8	Gene names	Mapk8ip1, Ib1, Jip1, Mapk8ip, Prkm8ip
Domain Architecture
Description	C-jun-amino-terminal kinase-interacting protein 1 (JNK-interacting protein 1) (JIP-1) (JNK MAP kinase scaffold protein 1) (Islet-brain-1) (IB-1) (Mitogen-activated protein kinase 8-interacting protein 1).

NF2L2_HUMAN
NC score	0.010270 (rank : 19)	θ value	8.99809 (rank : 18)
Query Neighborhood Hits	20	Target Neighborhood Hits	109	Shared Neighborhood Hits	2
SwissProt Accessions	Q16236, Q96F71	Gene names	NFE2L2, NRF2
Domain Architecture
Description	Nuclear factor erythroid 2-related factor 2 (NF-E2-related factor 2) (NFE2-related factor 2) (Nuclear factor, erythroid derived 2, like 2) (HEBP1).

UT14A_MOUSE
NC score	0.009725 (rank : 20)	θ value	8.99809 (rank : 20)
Query Neighborhood Hits	20	Target Neighborhood Hits	177	Shared Neighborhood Hits	2
SwissProt Accessions	Q640M1, Q6A094, Q6EJB4, Q6P6L1, Q9CZK8	Gene names	Utp14a, JsdX, Kiaa0266
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 14 homolog A (Juvenile spermatogonial depletion-like X-linked protein) (Jsd-like X-linked protein).

LRRC7_HUMAN
NC score	0.006372 (rank : 21)	θ value	5.27518 (rank : 13)
Query Neighborhood Hits	20	Target Neighborhood Hits	423	Shared Neighborhood Hits	2
SwissProt Accessions	Q96NW7, Q5VXC2, Q5VXC3, Q68D07, Q86VE8, Q8WX20, Q9P2I2	Gene names	LRRC7, KIAA1365, LAP1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 7 (Protein LAP1) (Densin-180).

TRHY_HUMAN
NC score	0.002842 (rank : 22)	θ value	8.99809 (rank : 19)
Query Neighborhood Hits	20	Target Neighborhood Hits	1385	Shared Neighborhood Hits	4
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.