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Network neighborhood for query Sequence : ERF1_HUMAN

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ERF1_HUMAN
SwissProt Accessions	P62495, P46055, Q5M7Z7	Gene names	ETF1, ERF1, RF1
Domain Architecture	No domain graphic available
Description	Eukaryotic peptide chain release factor subunit 1 (eRF1) (Eukaryotic release factor 1) (TB3-1) (Cl1 protein).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ERF1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	13
SwissProt Accessions	P62495, P46055, Q5M7Z7	Gene names	ETF1, ERF1, RF1
Domain Architecture	No domain graphic available
Description	Eukaryotic peptide chain release factor subunit 1 (eRF1) (Eukaryotic release factor 1) (TB3-1) (Cl1 protein).

ERF1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 2)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BWY3, Q3TPZ6, Q91VH9	Gene names	Etf1
Domain Architecture	No domain graphic available
Description	Eukaryotic peptide chain release factor subunit 1 (eRF1) (Eukaryotic release factor 1).

ZBT20_HUMAN
θ value	1.06291 (rank : 3)	NC score	0.009074 (rank : 12)
Query Neighborhood Hits	13	Target Neighborhood Hits	835	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HC78	Gene names	ZBTB20, DPZF, ZNF288
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 20 (Zinc finger protein 288) (Dendritic-derived BTB/POZ zinc finger protein).

SRC8_MOUSE
θ value	1.81305 (rank : 4)	NC score	0.040866 (rank : 4)
Query Neighborhood Hits	13	Target Neighborhood Hits	292	Shared Neighborhood Hits	5
SwissProt Accessions	Q60598	Gene names	Cttn, Ems1
Domain Architecture
Description	Src substrate cortactin.

NT5D1_HUMAN
θ value	2.36792 (rank : 5)	NC score	0.050041 (rank : 3)
Query Neighborhood Hits	13	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q5TFE4, Q6XYD5	Gene names	NT5DC1
Domain Architecture	No domain graphic available
Description	5'-nucleotidase domain-containing protein 1.

SRC8_HUMAN
θ value	2.36792 (rank : 6)	NC score	0.039690 (rank : 5)
Query Neighborhood Hits	13	Target Neighborhood Hits	269	Shared Neighborhood Hits	5
SwissProt Accessions	Q14247	Gene names	CTTN, EMS1
Domain Architecture
Description	Src substrate cortactin (Amplaxin) (Oncogene EMS1).

OSBL6_HUMAN
θ value	3.0926 (rank : 7)	NC score	0.030329 (rank : 7)
Query Neighborhood Hits	13	Target Neighborhood Hits	101	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BZF3, Q7Z4Q1, Q96SR1	Gene names	OSBPL6, ORP6
Domain Architecture
Description	Oxysterol-binding protein-related protein 6 (OSBP-related protein 6) (ORP-6).

OSBL6_MOUSE
θ value	3.0926 (rank : 8)	NC score	0.030594 (rank : 6)
Query Neighborhood Hits	13	Target Neighborhood Hits	105	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BXR9, Q8BYW2	Gene names	Osbpl6
Domain Architecture
Description	Oxysterol-binding protein-related protein 6 (OSBP-related protein 6) (ORP-6).

TRIPC_HUMAN
θ value	3.0926 (rank : 9)	NC score	0.025597 (rank : 8)
Query Neighborhood Hits	13	Target Neighborhood Hits	319	Shared Neighborhood Hits	3
SwissProt Accessions	Q14669, Q15644	Gene names	TRIP12, KIAA0045
Domain Architecture
Description	Thyroid receptor-interacting protein 12 (TRIP12).

ITPR3_HUMAN
θ value	4.03905 (rank : 10)	NC score	0.018925 (rank : 10)
Query Neighborhood Hits	13	Target Neighborhood Hits	114	Shared Neighborhood Hits	4
SwissProt Accessions	Q14573, Q14649	Gene names	ITPR3
Domain Architecture
Description	Inositol 1,4,5-trisphosphate receptor type 3 (Type 3 inositol 1,4,5- trisphosphate receptor) (Type 3 InsP3 receptor) (IP3 receptor isoform 3) (InsP3R3).

SMG1_HUMAN
θ value	4.03905 (rank : 11)	NC score	0.024103 (rank : 9)
Query Neighborhood Hits	13	Target Neighborhood Hits	231	Shared Neighborhood Hits	4
SwissProt Accessions	Q96Q15, O43305, Q13284, Q8NFX2, Q96QV0, Q96RW3	Gene names	SMG1, ATX, KIAA0421, LIP
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SMG1 (EC 2.7.11.1) (SMG-1) (hSMG-1) (Lambda/iota protein kinase C-interacting protein) (Lambda-interacting protein) (61E3.4).

TEC_HUMAN
θ value	6.88961 (rank : 12)	NC score	0.003008 (rank : 13)
Query Neighborhood Hits	13	Target Neighborhood Hits	1006	Shared Neighborhood Hits	5
SwissProt Accessions	P42680	Gene names	TEC, PSCTK4
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).

DHX57_MOUSE
θ value	8.99809 (rank : 13)	NC score	0.010229 (rank : 11)
Query Neighborhood Hits	13	Target Neighborhood Hits	125	Shared Neighborhood Hits	3
SwissProt Accessions	Q6P5D3, Q3TS93, Q6NZK4, Q6P1B4, Q8BI63, Q8BIA2, Q8R360	Gene names	Dhx57
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX57 (EC 3.6.1.-) (DEAH box protein 57).

Hits sorted by NC score

ERF1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	13
SwissProt Accessions	P62495, P46055, Q5M7Z7	Gene names	ETF1, ERF1, RF1
Domain Architecture	No domain graphic available
Description	Eukaryotic peptide chain release factor subunit 1 (eRF1) (Eukaryotic release factor 1) (TB3-1) (Cl1 protein).

ERF1_MOUSE
NC score	0.999962 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	13
SwissProt Accessions	Q8BWY3, Q3TPZ6, Q91VH9	Gene names	Etf1
Domain Architecture	No domain graphic available
Description	Eukaryotic peptide chain release factor subunit 1 (eRF1) (Eukaryotic release factor 1).

NT5D1_HUMAN
NC score	0.050041 (rank : 3)	θ value	2.36792 (rank : 5)
Query Neighborhood Hits	13	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q5TFE4, Q6XYD5	Gene names	NT5DC1
Domain Architecture	No domain graphic available
Description	5'-nucleotidase domain-containing protein 1.

SRC8_MOUSE
NC score	0.040866 (rank : 4)	θ value	1.81305 (rank : 4)
Query Neighborhood Hits	13	Target Neighborhood Hits	292	Shared Neighborhood Hits	5
SwissProt Accessions	Q60598	Gene names	Cttn, Ems1
Domain Architecture
Description	Src substrate cortactin.

SRC8_HUMAN
NC score	0.039690 (rank : 5)	θ value	2.36792 (rank : 6)
Query Neighborhood Hits	13	Target Neighborhood Hits	269	Shared Neighborhood Hits	5
SwissProt Accessions	Q14247	Gene names	CTTN, EMS1
Domain Architecture
Description	Src substrate cortactin (Amplaxin) (Oncogene EMS1).

OSBL6_MOUSE
NC score	0.030594 (rank : 6)	θ value	3.0926 (rank : 8)
Query Neighborhood Hits	13	Target Neighborhood Hits	105	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BXR9, Q8BYW2	Gene names	Osbpl6
Domain Architecture
Description	Oxysterol-binding protein-related protein 6 (OSBP-related protein 6) (ORP-6).

OSBL6_HUMAN
NC score	0.030329 (rank : 7)	θ value	3.0926 (rank : 7)
Query Neighborhood Hits	13	Target Neighborhood Hits	101	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BZF3, Q7Z4Q1, Q96SR1	Gene names	OSBPL6, ORP6
Domain Architecture
Description	Oxysterol-binding protein-related protein 6 (OSBP-related protein 6) (ORP-6).

TRIPC_HUMAN
NC score	0.025597 (rank : 8)	θ value	3.0926 (rank : 9)
Query Neighborhood Hits	13	Target Neighborhood Hits	319	Shared Neighborhood Hits	3
SwissProt Accessions	Q14669, Q15644	Gene names	TRIP12, KIAA0045
Domain Architecture
Description	Thyroid receptor-interacting protein 12 (TRIP12).

SMG1_HUMAN
NC score	0.024103 (rank : 9)	θ value	4.03905 (rank : 11)
Query Neighborhood Hits	13	Target Neighborhood Hits	231	Shared Neighborhood Hits	4
SwissProt Accessions	Q96Q15, O43305, Q13284, Q8NFX2, Q96QV0, Q96RW3	Gene names	SMG1, ATX, KIAA0421, LIP
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SMG1 (EC 2.7.11.1) (SMG-1) (hSMG-1) (Lambda/iota protein kinase C-interacting protein) (Lambda-interacting protein) (61E3.4).

ITPR3_HUMAN
NC score	0.018925 (rank : 10)	θ value	4.03905 (rank : 10)
Query Neighborhood Hits	13	Target Neighborhood Hits	114	Shared Neighborhood Hits	4
SwissProt Accessions	Q14573, Q14649	Gene names	ITPR3
Domain Architecture
Description	Inositol 1,4,5-trisphosphate receptor type 3 (Type 3 inositol 1,4,5- trisphosphate receptor) (Type 3 InsP3 receptor) (IP3 receptor isoform 3) (InsP3R3).

DHX57_MOUSE
NC score	0.010229 (rank : 11)	θ value	8.99809 (rank : 13)
Query Neighborhood Hits	13	Target Neighborhood Hits	125	Shared Neighborhood Hits	3
SwissProt Accessions	Q6P5D3, Q3TS93, Q6NZK4, Q6P1B4, Q8BI63, Q8BIA2, Q8R360	Gene names	Dhx57
Domain Architecture	No domain graphic available
Description	Putative ATP-dependent RNA helicase DHX57 (EC 3.6.1.-) (DEAH box protein 57).

ZBT20_HUMAN
NC score	0.009074 (rank : 12)	θ value	1.06291 (rank : 3)
Query Neighborhood Hits	13	Target Neighborhood Hits	835	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HC78	Gene names	ZBTB20, DPZF, ZNF288
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 20 (Zinc finger protein 288) (Dendritic-derived BTB/POZ zinc finger protein).

TEC_HUMAN
NC score	0.003008 (rank : 13)	θ value	6.88961 (rank : 12)
Query Neighborhood Hits	13	Target Neighborhood Hits	1006	Shared Neighborhood Hits	5
SwissProt Accessions	P42680	Gene names	TEC, PSCTK4
Domain Architecture
Description	Tyrosine-protein kinase Tec (EC 2.7.10.2).