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Network neighborhood for query Sequence : PAP2_HUMAN

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PAP2_HUMAN
SwissProt Accessions	Q9BXP8, Q96PH7, Q96PH8, Q9H4C9	Gene names	PAPPA2
Domain Architecture	No domain graphic available
Description	Pappalysin-2 precursor (EC 3.4.24.-) (Pregnancy-associated plasma protein-A2) (PAPP-A2) (Pregnancy-associated plasma protein-E1) (PAPP- E).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PAP2_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	106	Target Neighborhood Hits	106	Shared Neighborhood Hits	106
SwissProt Accessions	Q9BXP8, Q96PH7, Q96PH8, Q9H4C9	Gene names	PAPPA2
Domain Architecture	No domain graphic available
Description	Pappalysin-2 precursor (EC 3.4.24.-) (Pregnancy-associated plasma protein-A2) (PAPP-A2) (Pregnancy-associated plasma protein-E1) (PAPP- E).

PAPPA_HUMAN
θ value	0 (rank : 2)	NC score	0.947119 (rank : 3)
Query Neighborhood Hits	106	Target Neighborhood Hits	161	Shared Neighborhood Hits	73
SwissProt Accessions	Q13219, Q08371, Q68G52, Q9UDK7	Gene names	PAPPA
Domain Architecture
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

PAPPA_MOUSE
θ value	0 (rank : 3)	NC score	0.951476 (rank : 2)
Query Neighborhood Hits	106	Target Neighborhood Hits	153	Shared Neighborhood Hits	69
SwissProt Accessions	Q8R4K8, Q80VW3, Q80YY1, Q8K423, Q8R4K7, Q9ES06, Q9JK57	Gene names	Pappa
Domain Architecture	No domain graphic available
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

DAF2_MOUSE
θ value	5.8054e-15 (rank : 4)	NC score	0.574623 (rank : 4)
Query Neighborhood Hits	106	Target Neighborhood Hits	114	Shared Neighborhood Hits	55
SwissProt Accessions	Q61476	Gene names	Cd55b, Daf2
Domain Architecture
Description	Complement decay-accelerating factor transmembrane isoform precursor (DAF-TM) (CD55 antigen).

DAF1_MOUSE
θ value	2.20605e-14 (rank : 5)	NC score	0.567521 (rank : 5)
Query Neighborhood Hits	106	Target Neighborhood Hits	204	Shared Neighborhood Hits	58
SwissProt Accessions	Q61475, P97732, Q61397	Gene names	Cd55a, Daf1
Domain Architecture
Description	Complement decay-accelerating factor, GPI-anchored precursor (DAF-GPI) (CD55 antigen).

LYAM3_HUMAN
θ value	1.86753e-13 (rank : 6)	NC score	0.494863 (rank : 13)
Query Neighborhood Hits	106	Target Neighborhood Hits	378	Shared Neighborhood Hits	76
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

DAF_HUMAN
θ value	1.58096e-12 (rank : 7)	NC score	0.555361 (rank : 6)
Query Neighborhood Hits	106	Target Neighborhood Hits	97	Shared Neighborhood Hits	54
SwissProt Accessions	P08174, P09679, P78361	Gene names	CD55, CR, DAF
Domain Architecture
Description	Complement decay-accelerating factor precursor (CD55 antigen).

LYAM2_HUMAN
θ value	3.52202e-12 (rank : 8)	NC score	0.481532 (rank : 18)
Query Neighborhood Hits	106	Target Neighborhood Hits	394	Shared Neighborhood Hits	77
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

LYAM2_MOUSE
θ value	1.74796e-11 (rank : 9)	NC score	0.471087 (rank : 24)
Query Neighborhood Hits	106	Target Neighborhood Hits	420	Shared Neighborhood Hits	78
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

LYAM3_MOUSE
θ value	3.89403e-11 (rank : 10)	NC score	0.482755 (rank : 17)
Query Neighborhood Hits	106	Target Neighborhood Hits	390	Shared Neighborhood Hits	78
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

CR1_HUMAN
θ value	5.62301e-10 (rank : 11)	NC score	0.513192 (rank : 7)
Query Neighborhood Hits	106	Target Neighborhood Hits	108	Shared Neighborhood Hits	58
SwissProt Accessions	P17927, Q16745, Q9UQV2	Gene names	CR1, C3BR
Domain Architecture
Description	Complement receptor type 1 precursor (C3b/C4b receptor) (CD35 antigen).

CSMD1_MOUSE
θ value	1.63604e-09 (rank : 12)	NC score	0.400338 (rank : 36)
Query Neighborhood Hits	106	Target Neighborhood Hits	193	Shared Neighborhood Hits	61
SwissProt Accessions	Q923L3, Q8BUV1, Q8BYQ3	Gene names	Csmd1
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

CFAH_HUMAN
θ value	2.13673e-09 (rank : 13)	NC score	0.480086 (rank : 20)
Query Neighborhood Hits	106	Target Neighborhood Hits	101	Shared Neighborhood Hits	58
SwissProt Accessions	P08603, P78435, Q14570, Q38G77, Q5TFM3, Q8N708, Q9NU86	Gene names	CFH, HF, HF1
Domain Architecture
Description	Complement factor H precursor (H factor 1).

CFAH_MOUSE
θ value	2.13673e-09 (rank : 14)	NC score	0.495166 (rank : 12)
Query Neighborhood Hits	106	Target Neighborhood Hits	112	Shared Neighborhood Hits	59
SwissProt Accessions	P06909	Gene names	Cfh, Hf1
Domain Architecture
Description	Complement factor H precursor (Protein beta-1-H).

CR2_MOUSE
θ value	2.79066e-09 (rank : 15)	NC score	0.504306 (rank : 10)
Query Neighborhood Hits	106	Target Neighborhood Hits	101	Shared Neighborhood Hits	56
SwissProt Accessions	P19070	Gene names	Cr2
Domain Architecture
Description	Complement receptor type 2 precursor (Cr2) (Complement C3d receptor) (CD21 antigen).

CR2_HUMAN
θ value	1.80886e-08 (rank : 16)	NC score	0.505508 (rank : 8)
Query Neighborhood Hits	106	Target Neighborhood Hits	89	Shared Neighborhood Hits	57
SwissProt Accessions	P20023, Q13866, Q14212	Gene names	CR2, C3DR
Domain Architecture
Description	Complement receptor type 2 precursor (Cr2) (Complement C3d receptor) (Epstein-Barr virus receptor) (EBV receptor) (CD21 antigen).

CSMD3_HUMAN
θ value	3.41135e-07 (rank : 17)	NC score	0.395823 (rank : 38)
Query Neighborhood Hits	106	Target Neighborhood Hits	199	Shared Neighborhood Hits	62
SwissProt Accessions	Q7Z407, Q96PZ3	Gene names	CSMD3, KIAA1894
Domain Architecture
Description	CUB and sushi domain-containing protein 3 precursor (CUB and sushi multiple domains protein 3).

ZP3R_MOUSE
θ value	7.59969e-07 (rank : 18)	NC score	0.504948 (rank : 9)
Query Neighborhood Hits	106	Target Neighborhood Hits	81	Shared Neighborhood Hits	55
SwissProt Accessions	Q60736	Gene names	Zp3r, Sp56
Domain Architecture
Description	Zona pellucida sperm-binding protein 3 receptor precursor (Sperm fertilization protein 56) (sp56).

CSMD2_HUMAN
θ value	9.92553e-07 (rank : 19)	NC score	0.386791 (rank : 39)
Query Neighborhood Hits	106	Target Neighborhood Hits	188	Shared Neighborhood Hits	59
SwissProt Accessions	Q7Z408, Q5VT59, Q8N963, Q96Q03, Q9H4V7, Q9H4V8, Q9H4V9, Q9H4W0, Q9H4W1, Q9H4W2, Q9H4W3, Q9H4W4, Q9HCY5, Q9HCY6, Q9HCY7	Gene names	CSMD2, KIAA1884
Domain Architecture
Description	CUB and sushi domain-containing protein 2 (CUB and sushi multiple domains protein 2).

CSMD1_HUMAN
θ value	2.21117e-06 (rank : 20)	NC score	0.396419 (rank : 37)
Query Neighborhood Hits	106	Target Neighborhood Hits	176	Shared Neighborhood Hits	61
SwissProt Accessions	Q96PZ7, Q96QU9, Q96RM4	Gene names	CSMD1, KIAA1890
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

F13B_MOUSE
θ value	2.21117e-06 (rank : 21)	NC score	0.472587 (rank : 23)
Query Neighborhood Hits	106	Target Neighborhood Hits	93	Shared Neighborhood Hits	58
SwissProt Accessions	Q07968	Gene names	F13b, Cf13b
Domain Architecture
Description	Coagulation factor XIII B chain precursor (Protein-glutamine gamma- glutamyltransferase B chain) (Transglutaminase B chain).

FHR4_HUMAN
θ value	4.92598e-06 (rank : 22)	NC score	0.401258 (rank : 35)
Query Neighborhood Hits	106	Target Neighborhood Hits	75	Shared Neighborhood Hits	52
SwissProt Accessions	Q92496, Q9UJY6	Gene names	CFHL4, FHR4
Domain Architecture
Description	Complement factor H-related protein 4 precursor (FHR-4).

SRPX_HUMAN
θ value	1.09739e-05 (rank : 23)	NC score	0.480382 (rank : 19)
Query Neighborhood Hits	106	Target Neighborhood Hits	69	Shared Neighborhood Hits	44
SwissProt Accessions	P78539, Q99652, Q99913	Gene names	SRPX, ETX1
Domain Architecture
Description	Sushi repeat-containing protein SRPX precursor.

FHR3_HUMAN
θ value	3.19293e-05 (rank : 24)	NC score	0.410973 (rank : 33)
Query Neighborhood Hits	106	Target Neighborhood Hits	74	Shared Neighborhood Hits	50
SwissProt Accessions	Q02985, Q9UJ16	Gene names	CFHL3, FHR3
Domain Architecture
Description	Complement factor H-related protein 3 precursor (FHR-3) (H factor-like protein 3) (DOWN16).

C4BP_HUMAN
θ value	4.1701e-05 (rank : 25)	NC score	0.495982 (rank : 11)
Query Neighborhood Hits	106	Target Neighborhood Hits	92	Shared Neighborhood Hits	58
SwissProt Accessions	P04003	Gene names	C4BPA, C4BP
Domain Architecture
Description	C4b-binding protein alpha chain precursor (C4bp) (Proline-rich protein) (PRP).

F13B_HUMAN
θ value	4.1701e-05 (rank : 26)	NC score	0.470038 (rank : 25)
Query Neighborhood Hits	106	Target Neighborhood Hits	84	Shared Neighborhood Hits	51
SwissProt Accessions	P05160	Gene names	F13B
Domain Architecture
Description	Coagulation factor XIII B chain precursor (Protein-glutamine gamma- glutamyltransferase B chain) (Transglutaminase B chain) (Fibrin- stabilizing factor B subunit).

SUSD4_HUMAN
θ value	4.1701e-05 (rank : 27)	NC score	0.449588 (rank : 26)
Query Neighborhood Hits	106	Target Neighborhood Hits	88	Shared Neighborhood Hits	49
SwissProt Accessions	Q5VX71, Q6UX62, Q9BSR0, Q9NWG0	Gene names	SUSD4
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 4 precursor.

C4BB_HUMAN
θ value	5.44631e-05 (rank : 28)	NC score	0.472784 (rank : 22)
Query Neighborhood Hits	106	Target Neighborhood Hits	77	Shared Neighborhood Hits	51
SwissProt Accessions	P20851	Gene names	C4BPB
Domain Architecture
Description	C4b-binding protein beta chain precursor.

C4BP_MOUSE
θ value	5.44631e-05 (rank : 29)	NC score	0.483562 (rank : 16)
Query Neighborhood Hits	106	Target Neighborhood Hits	91	Shared Neighborhood Hits	55
SwissProt Accessions	P08607	Gene names	C4bpa, C4bp
Domain Architecture
Description	C4b-binding protein precursor (C4bp).

SUSD1_HUMAN
θ value	5.44631e-05 (rank : 30)	NC score	0.240918 (rank : 44)
Query Neighborhood Hits	106	Target Neighborhood Hits	285	Shared Neighborhood Hits	62
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

SRPX_MOUSE
θ value	9.29e-05 (rank : 31)	NC score	0.480026 (rank : 21)
Query Neighborhood Hits	106	Target Neighborhood Hits	75	Shared Neighborhood Hits	46
SwissProt Accessions	Q9R0M3, Q9R0M2	Gene names	Srpx
Domain Architecture	No domain graphic available
Description	Sushi-repeat-containing protein SRPX precursor (DRS protein).

APOH_MOUSE
θ value	0.00020696 (rank : 32)	NC score	0.490783 (rank : 14)
Query Neighborhood Hits	106	Target Neighborhood Hits	74	Shared Neighborhood Hits	53
SwissProt Accessions	Q01339	Gene names	Apoh, B2gp1
Domain Architecture
Description	Beta-2-glycoprotein 1 precursor (Beta-2-glycoprotein I) (Apolipoprotein H) (Apo-H) (B2GPI) (Beta(2)GPI) (Activated protein C- binding protein) (APC inhibitor).

SUSD4_MOUSE
θ value	0.00035302 (rank : 33)	NC score	0.425952 (rank : 30)
Query Neighborhood Hits	106	Target Neighborhood Hits	122	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BH32, Q8VC43	Gene names	Susd4
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 4 precursor.

CO2_HUMAN
θ value	0.000786445 (rank : 34)	NC score	0.252878 (rank : 43)
Query Neighborhood Hits	106	Target Neighborhood Hits	258	Shared Neighborhood Hits	53
SwissProt Accessions	P06681, O19694, Q13904	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

LYAM1_MOUSE
θ value	0.00228821 (rank : 35)	NC score	0.370350 (rank : 40)
Query Neighborhood Hits	106	Target Neighborhood Hits	332	Shared Neighborhood Hits	64
SwissProt Accessions	P18337	Gene names	Sell, Lnhr, Ly-22
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Lymphocyte antigen 22) (Ly-22) (Lymphocyte surface MEL-14 antigen) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

NOTC4_HUMAN
θ value	0.00228821 (rank : 36)	NC score	0.080892 (rank : 84)
Query Neighborhood Hits	106	Target Neighborhood Hits	905	Shared Neighborhood Hits	55
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

FHR2_HUMAN
θ value	0.00869519 (rank : 37)	NC score	0.413320 (rank : 32)
Query Neighborhood Hits	106	Target Neighborhood Hits	63	Shared Neighborhood Hits	47
SwissProt Accessions	P36980, Q14310	Gene names	CFHL2, FHR2, HFL3
Domain Architecture
Description	Complement factor H-related protein 2 precursor (FHR-2) (H factor-like protein 2) (H factor-like 3) (DDESK59).

ADAM7_MOUSE
θ value	0.0330416 (rank : 38)	NC score	0.032987 (rank : 168)
Query Neighborhood Hits	106	Target Neighborhood Hits	200	Shared Neighborhood Hits	24
SwissProt Accessions	O35227	Gene names	Adam7
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7).

NOTC4_MOUSE
θ value	0.0330416 (rank : 39)	NC score	0.078017 (rank : 90)
Query Neighborhood Hits	106	Target Neighborhood Hits	872	Shared Neighborhood Hits	55
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

NOTC2_MOUSE
θ value	0.0431538 (rank : 40)	NC score	0.080203 (rank : 86)
Query Neighborhood Hits	106	Target Neighborhood Hits	1069	Shared Neighborhood Hits	55
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

TNR14_HUMAN
θ value	0.0431538 (rank : 41)	NC score	0.083923 (rank : 78)
Query Neighborhood Hits	106	Target Neighborhood Hits	149	Shared Neighborhood Hits	22
SwissProt Accessions	Q92956, Q8WXR1, Q96J31, Q9UM65	Gene names	TNFRSF14, HVEA, HVEM
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 14 precursor (Herpesvirus entry mediator A) (Tumor necrosis factor receptor-like 2) (TR2).

FHR1_HUMAN
θ value	0.0563607 (rank : 42)	NC score	0.430880 (rank : 29)
Query Neighborhood Hits	106	Target Neighborhood Hits	80	Shared Neighborhood Hits	53
SwissProt Accessions	Q03591, Q9UJ17	Gene names	CFHL1, CFHL, FHR1, HFL1
Domain Architecture
Description	Complement factor H-related protein 1 precursor (FHR-1) (H factor-like protein 1) (H-factor-like 1) (H36).

NOTC1_MOUSE
θ value	0.0563607 (rank : 43)	NC score	0.087771 (rank : 69)
Query Neighborhood Hits	106	Target Neighborhood Hits	916	Shared Neighborhood Hits	58
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

FHR5_HUMAN
θ value	0.0736092 (rank : 44)	NC score	0.432495 (rank : 28)
Query Neighborhood Hits	106	Target Neighborhood Hits	77	Shared Neighborhood Hits	52
SwissProt Accessions	Q9BXR6	Gene names	CFHL5, FHR5
Domain Architecture
Description	Complement factor H-related protein 5 precursor (FHR-5).

GNPTA_MOUSE
θ value	0.0736092 (rank : 45)	NC score	0.132298 (rank : 54)
Query Neighborhood Hits	106	Target Neighborhood Hits	47	Shared Neighborhood Hits	13
SwissProt Accessions	Q69ZN6, Q3U3K6, Q3US34	Gene names	Gnptab, Gnpta, Kiaa1208
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphotransferase subunits alpha/beta precursor (EC 2.7.8.17) (GlcNAc-1-phosphotransferase alpha/beta subunits) (UDP- N-acetylglucosamine-1-phosphotransferase alpha/beta subunits) (Stealth protein GNPTAB) [Contains: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta].

NOTC1_HUMAN
θ value	0.0736092 (rank : 46)	NC score	0.083642 (rank : 79)
Query Neighborhood Hits	106	Target Neighborhood Hits	906	Shared Neighborhood Hits	60
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC3_HUMAN
θ value	0.0736092 (rank : 47)	NC score	0.084779 (rank : 77)
Query Neighborhood Hits	106	Target Neighborhood Hits	1062	Shared Neighborhood Hits	58
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC3_MOUSE
θ value	0.0736092 (rank : 48)	NC score	0.085692 (rank : 74)
Query Neighborhood Hits	106	Target Neighborhood Hits	975	Shared Neighborhood Hits	55
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

PCSK5_MOUSE
θ value	0.0736092 (rank : 49)	NC score	0.075479 (rank : 92)
Query Neighborhood Hits	106	Target Neighborhood Hits	613	Shared Neighborhood Hits	43
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

SSPO_MOUSE
θ value	0.0736092 (rank : 50)	NC score	0.055235 (rank : 142)
Query Neighborhood Hits	106	Target Neighborhood Hits	800	Shared Neighborhood Hits	46
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

TNR8_MOUSE
θ value	0.0736092 (rank : 51)	NC score	0.058785 (rank : 122)
Query Neighborhood Hits	106	Target Neighborhood Hits	208	Shared Neighborhood Hits	16
SwissProt Accessions	Q60846	Gene names	Tnfrsf8
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30).

LYAM1_HUMAN
θ value	0.0961366 (rank : 52)	NC score	0.355973 (rank : 41)
Query Neighborhood Hits	106	Target Neighborhood Hits	315	Shared Neighborhood Hits	64
SwissProt Accessions	P14151, P15023	Gene names	SELL, LNHR, LYAM1
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte surface antigen Leu-8) (TQ1) (gp90-MEL) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

NOTC2_HUMAN
θ value	0.0961366 (rank : 53)	NC score	0.081247 (rank : 83)
Query Neighborhood Hits	106	Target Neighborhood Hits	1113	Shared Neighborhood Hits	58
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

CRRY_MOUSE
θ value	0.125558 (rank : 54)	NC score	0.484449 (rank : 15)
Query Neighborhood Hits	106	Target Neighborhood Hits	84	Shared Neighborhood Hits	55
SwissProt Accessions	Q64735, Q3TV30, Q58E68, Q61447, Q61449, Q8CF59, Q8K328	Gene names	Crry, Cry
Domain Architecture	No domain graphic available
Description	Complement regulatory protein Crry precursor (Protein p65).

PCSK5_HUMAN
θ value	0.125558 (rank : 55)	NC score	0.050669 (rank : 161)
Query Neighborhood Hits	106	Target Neighborhood Hits	291	Shared Neighborhood Hits	33
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

APOH_HUMAN
θ value	0.163984 (rank : 56)	NC score	0.442473 (rank : 27)
Query Neighborhood Hits	106	Target Neighborhood Hits	75	Shared Neighborhood Hits	53
SwissProt Accessions	P02749, Q9UCN7	Gene names	APOH, B2G1
Domain Architecture
Description	Beta-2-glycoprotein 1 precursor (Beta-2-glycoprotein I) (Apolipoprotein H) (Apo-H) (B2GPI) (Beta(2)GPI) (Activated protein C- binding protein) (APC inhibitor) (Anticardiolipin cofactor).

C1R_HUMAN
θ value	0.163984 (rank : 57)	NC score	0.078958 (rank : 89)
Query Neighborhood Hits	106	Target Neighborhood Hits	364	Shared Neighborhood Hits	56
SwissProt Accessions	P00736, Q8J012	Gene names	C1R
Domain Architecture
Description	Complement C1r subcomponent precursor (EC 3.4.21.41) (Complement component 1, r subcomponent) [Contains: Complement C1r subcomponent heavy chain; Complement C1r subcomponent light chain].

GNPTA_HUMAN
θ value	0.21417 (rank : 58)	NC score	0.123810 (rank : 57)
Query Neighborhood Hits	106	Target Neighborhood Hits	43	Shared Neighborhood Hits	13
SwissProt Accessions	Q3T906, Q3ZQK2, Q6IPW5, Q86TQ2, Q96N13, Q9ULL2	Gene names	GNPTAB, GNPTA, KIAA1208
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphotransferase subunits alpha/beta precursor (EC 2.7.8.17) (GlcNAc-1-phosphotransferase alpha/beta subunits) (UDP- N-acetylglucosamine-1-phosphotransferase alpha/beta subunits) (Stealth protein GNPTAB) [Contains: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta].

ADM1A_MOUSE
θ value	0.279714 (rank : 59)	NC score	0.030983 (rank : 172)
Query Neighborhood Hits	106	Target Neighborhood Hits	230	Shared Neighborhood Hits	29
SwissProt Accessions	Q60813, Q60617, Q80WR7, Q8R533	Gene names	Adam1a, Adam1, Ftna
Domain Architecture
Description	ADAM 1a precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1a) (Fertilin alpha 1a subunit).

ADA17_HUMAN
θ value	0.365318 (rank : 60)	NC score	0.041074 (rank : 163)
Query Neighborhood Hits	106	Target Neighborhood Hits	223	Shared Neighborhood Hits	26
SwissProt Accessions	P78536, O60226	Gene names	ADAM17, CSVP, TACE
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen).

ATS7_HUMAN
θ value	0.365318 (rank : 61)	NC score	0.019955 (rank : 176)
Query Neighborhood Hits	106	Target Neighborhood Hits	169	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UKP4	Gene names	ADAMTS7
Domain Architecture
Description	ADAMTS-7 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 7) (ADAM-TS 7) (ADAM-TS7).

MASP2_MOUSE
θ value	0.365318 (rank : 62)	NC score	0.122173 (rank : 58)
Query Neighborhood Hits	106	Target Neighborhood Hits	382	Shared Neighborhood Hits	61
SwissProt Accessions	Q91WP0, Q9QXA4, Q9QXD2, Q9QXD5, Q9Z338	Gene names	Masp2
Domain Architecture	No domain graphic available
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

LAMC3_HUMAN
θ value	0.47712 (rank : 63)	NC score	0.051823 (rank : 158)
Query Neighborhood Hits	106	Target Neighborhood Hits	588	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

ADAM8_HUMAN
θ value	0.62314 (rank : 64)	NC score	0.033103 (rank : 167)
Query Neighborhood Hits	106	Target Neighborhood Hits	327	Shared Neighborhood Hits	31
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

ADA10_MOUSE
θ value	0.813845 (rank : 65)	NC score	0.037239 (rank : 166)
Query Neighborhood Hits	106	Target Neighborhood Hits	194	Shared Neighborhood Hits	18
SwissProt Accessions	O35598	Gene names	Adam10, Kuz, Madm
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog).

JAG1_HUMAN
θ value	1.06291 (rank : 66)	NC score	0.072386 (rank : 98)
Query Neighborhood Hits	106	Target Neighborhood Hits	514	Shared Neighborhood Hits	51
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

LTBP2_MOUSE
θ value	1.06291 (rank : 67)	NC score	0.072053 (rank : 100)
Query Neighborhood Hits	106	Target Neighborhood Hits	617	Shared Neighborhood Hits	52
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

PGCB_HUMAN
θ value	1.06291 (rank : 68)	NC score	0.087502 (rank : 70)
Query Neighborhood Hits	106	Target Neighborhood Hits	478	Shared Neighborhood Hits	57
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

TNAP3_MOUSE
θ value	1.06291 (rank : 69)	NC score	0.028335 (rank : 173)
Query Neighborhood Hits	106	Target Neighborhood Hits	35	Shared Neighborhood Hits	6
SwissProt Accessions	Q60769	Gene names	Tnfaip3, Tnfip3
Domain Architecture
Description	Tumor necrosis factor, alpha-induced protein 3 (EC 3.-.-.-) (Putative DNA-binding protein A20) (Zinc finger protein A20).

CO2_MOUSE
θ value	1.38821 (rank : 70)	NC score	0.192992 (rank : 47)
Query Neighborhood Hits	106	Target Neighborhood Hits	250	Shared Neighborhood Hits	53
SwissProt Accessions	P21180	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

CS1A_MOUSE
θ value	1.38821 (rank : 71)	NC score	0.094178 (rank : 64)
Query Neighborhood Hits	106	Target Neighborhood Hits	360	Shared Neighborhood Hits	58
SwissProt Accessions	Q8CG14, Q8BJC4, Q8CH28, Q8VBY4	Gene names	C1sa, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-A subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-A subcomponent heavy chain; Complement C1s-A subcomponent light chain].

CS1B_MOUSE
θ value	1.38821 (rank : 72)	NC score	0.095836 (rank : 62)
Query Neighborhood Hits	106	Target Neighborhood Hits	361	Shared Neighborhood Hits	58
SwissProt Accessions	Q8CFG8	Gene names	C1sb, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-B subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-B subcomponent heavy chain; Complement C1s-B subcomponent light chain].

LAMA5_MOUSE
θ value	1.38821 (rank : 73)	NC score	0.045538 (rank : 162)
Query Neighborhood Hits	106	Target Neighborhood Hits	828	Shared Neighborhood Hits	41
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

PGCB_MOUSE
θ value	1.38821 (rank : 74)	NC score	0.079946 (rank : 87)
Query Neighborhood Hits	106	Target Neighborhood Hits	459	Shared Neighborhood Hits	57
SwissProt Accessions	Q61361	Gene names	Bcan
Domain Architecture
Description	Brevican core protein precursor.

USH2A_HUMAN
θ value	1.38821 (rank : 75)	NC score	0.039285 (rank : 165)
Query Neighborhood Hits	106	Target Neighborhood Hits	600	Shared Neighborhood Hits	34
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

FAAA_MOUSE
θ value	1.81305 (rank : 76)	NC score	0.026272 (rank : 175)
Query Neighborhood Hits	106	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	P35505	Gene names	Fah
Domain Architecture
Description	Fumarylacetoacetase (EC 3.7.1.2) (Fumarylacetoacetate hydrolase) (Beta-diketonase) (FAA).

HXA5_MOUSE
θ value	1.81305 (rank : 77)	NC score	0.006494 (rank : 182)
Query Neighborhood Hits	106	Target Neighborhood Hits	338	Shared Neighborhood Hits	4
SwissProt Accessions	P09021, Q91VQ5	Gene names	Hoxa5, Hox-1.3, Hoxa-5
Domain Architecture
Description	Homeobox protein Hox-A5 (Hox-1.3) (M2).

COLQ_HUMAN
θ value	2.36792 (rank : 78)	NC score	0.032592 (rank : 170)
Query Neighborhood Hits	106	Target Neighborhood Hits	193	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y215, Q6DK18, Q6YH18, Q6YH19, Q6YH20, Q6YH21, Q9NP18, Q9NP19, Q9NP20, Q9NP21, Q9NP22, Q9NP23, Q9NP24, Q9UP88	Gene names	COLQ
Domain Architecture	No domain graphic available
Description	Acetylcholinesterase collagenic tail peptide precursor (AChE Q subunit) (Acetylcholinesterase-associated collagen).

ADA25_MOUSE
θ value	3.0926 (rank : 79)	NC score	0.027184 (rank : 174)
Query Neighborhood Hits	106	Target Neighborhood Hits	213	Shared Neighborhood Hits	23
SwissProt Accessions	Q9R159, Q9D4E4	Gene names	Adam25
Domain Architecture
Description	ADAM 25 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 25) (Testase 2).

NELL2_MOUSE
θ value	3.0926 (rank : 80)	NC score	0.051543 (rank : 160)
Query Neighborhood Hits	106	Target Neighborhood Hits	436	Shared Neighborhood Hits	43
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

PGCA_MOUSE
θ value	3.0926 (rank : 81)	NC score	0.068369 (rank : 104)
Query Neighborhood Hits	106	Target Neighborhood Hits	643	Shared Neighborhood Hits	42
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

ZN548_HUMAN
θ value	3.0926 (rank : 82)	NC score	-0.002822 (rank : 188)
Query Neighborhood Hits	106	Target Neighborhood Hits	739	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NEK5, Q96M05	Gene names	ZNF548
Domain Architecture	No domain graphic available
Description	Zinc finger protein 548.

APR3_MOUSE
θ value	4.03905 (rank : 83)	NC score	0.040036 (rank : 164)
Query Neighborhood Hits	106	Target Neighborhood Hits	61	Shared Neighborhood Hits	13
SwissProt Accessions	Q6PGD0, Q3UAH4, Q810Q3, Q9DD14	Gene names	Apr3
Domain Architecture	No domain graphic available
Description	Apoptosis-related protein 3 precursor (APR-3).

BAT2_MOUSE
θ value	4.03905 (rank : 84)	NC score	0.011406 (rank : 180)
Query Neighborhood Hits	106	Target Neighborhood Hits	947	Shared Neighborhood Hits	11
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

HXA5_HUMAN
θ value	4.03905 (rank : 85)	NC score	0.005175 (rank : 183)
Query Neighborhood Hits	106	Target Neighborhood Hits	336	Shared Neighborhood Hits	4
SwissProt Accessions	P20719, O43367, Q96CY6	Gene names	HOXA5, HOX1C
Domain Architecture
Description	Homeobox protein Hox-A5 (Hox-1C).

MYT1_HUMAN
θ value	4.03905 (rank : 86)	NC score	0.008754 (rank : 181)
Query Neighborhood Hits	106	Target Neighborhood Hits	475	Shared Neighborhood Hits	3
SwissProt Accessions	Q01538, O94922, Q9UPV2	Gene names	MYT1, KIAA0835, KIAA1050, MTF1, MYTI, PLPB1
Domain Architecture
Description	Myelin transcription factor 1 (MyT1) (MyTI) (Proteolipid protein- binding protein) (PLPB1).

T2EA_HUMAN
θ value	4.03905 (rank : 87)	NC score	0.019080 (rank : 178)
Query Neighborhood Hits	106	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	P29083, Q16103	Gene names	GTF2E1, TF2E1
Domain Architecture
Description	Transcription initiation factor IIE subunit alpha (TFIIE-alpha) (General transcription factor IIE 56 kDa subunit).

CFAB_MOUSE
θ value	5.27518 (rank : 88)	NC score	0.211648 (rank : 45)
Query Neighborhood Hits	106	Target Neighborhood Hits	262	Shared Neighborhood Hits	54
SwissProt Accessions	P04186	Gene names	Cfb, Bf, H2-Bf
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

PGCA_HUMAN
θ value	5.27518 (rank : 89)	NC score	0.072967 (rank : 96)
Query Neighborhood Hits	106	Target Neighborhood Hits	821	Shared Neighborhood Hits	59
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

SEZ6L_HUMAN
θ value	5.27518 (rank : 90)	NC score	0.324446 (rank : 42)
Query Neighborhood Hits	106	Target Neighborhood Hits	289	Shared Neighborhood Hits	55
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

STAB1_MOUSE
θ value	5.27518 (rank : 91)	NC score	0.055622 (rank : 140)
Query Neighborhood Hits	106	Target Neighborhood Hits	566	Shared Neighborhood Hits	48
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

TITIN_HUMAN
θ value	5.27518 (rank : 92)	NC score	-0.002290 (rank : 186)
Query Neighborhood Hits	106	Target Neighborhood Hits	2923	Shared Neighborhood Hits	17
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

C1S_HUMAN
θ value	6.88961 (rank : 93)	NC score	0.111049 (rank : 59)
Query Neighborhood Hits	106	Target Neighborhood Hits	359	Shared Neighborhood Hits	57
SwissProt Accessions	P09871, Q9UCU7, Q9UCU8, Q9UCU9, Q9UCV0, Q9UCV1, Q9UCV2, Q9UCV3, Q9UCV4, Q9UCV5, Q9UM14	Gene names	C1S
Domain Architecture
Description	Complement C1s subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s subcomponent heavy chain; Complement C1s subcomponent light chain].

CO8A_HUMAN
θ value	6.88961 (rank : 94)	NC score	0.015467 (rank : 179)
Query Neighborhood Hits	106	Target Neighborhood Hits	200	Shared Neighborhood Hits	17
SwissProt Accessions	P07357, Q13668, Q9H130	Gene names	C8A
Domain Architecture
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

COIA1_MOUSE
θ value	6.88961 (rank : 95)	NC score	0.004958 (rank : 184)
Query Neighborhood Hits	106	Target Neighborhood Hits	481	Shared Neighborhood Hits	10
SwissProt Accessions	P39061, Q60672, Q61437, Q62001, Q62002, Q9JK63	Gene names	Col18a1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

FBN1_MOUSE
θ value	6.88961 (rank : 96)	NC score	0.065547 (rank : 107)
Query Neighborhood Hits	106	Target Neighborhood Hits	563	Shared Neighborhood Hits	50
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

FRAS1_HUMAN
θ value	6.88961 (rank : 97)	NC score	0.051916 (rank : 157)
Query Neighborhood Hits	106	Target Neighborhood Hits	759	Shared Neighborhood Hits	42
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

GALT6_MOUSE
θ value	6.88961 (rank : 98)	NC score	0.003157 (rank : 185)
Query Neighborhood Hits	106	Target Neighborhood Hits	57	Shared Neighborhood Hits	2
SwissProt Accessions	Q8C7U7, Q3TWF0, Q8CED2, Q9QZ16	Gene names	Galnt6
Domain Architecture	No domain graphic available
Description	Polypeptide N-acetylgalactosaminyltransferase 6 (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase 6) (UDP- GalNAc:polypeptide N-acetylgalactosaminyltransferase 6) (Polypeptide GalNAc transferase 6) (GalNAc-T6) (pp-GaNTase 6).

ITB6_MOUSE
θ value	6.88961 (rank : 99)	NC score	0.030997 (rank : 171)
Query Neighborhood Hits	106	Target Neighborhood Hits	341	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Z0T9	Gene names	Itgb6
Domain Architecture
Description	Integrin beta-6 precursor.

JAG1_MOUSE
θ value	6.88961 (rank : 100)	NC score	0.071647 (rank : 102)
Query Neighborhood Hits	106	Target Neighborhood Hits	518	Shared Neighborhood Hits	50
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

ADA10_HUMAN
θ value	8.99809 (rank : 101)	NC score	0.032665 (rank : 169)
Query Neighborhood Hits	106	Target Neighborhood Hits	189	Shared Neighborhood Hits	18
SwissProt Accessions	O14672, Q10742, Q92650	Gene names	ADAM10, KUZ, MADM
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog) (CDw156c antigen).

CO6_HUMAN
θ value	8.99809 (rank : 102)	NC score	0.166071 (rank : 51)
Query Neighborhood Hits	106	Target Neighborhood Hits	331	Shared Neighborhood Hits	66
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

FRAS1_MOUSE
θ value	8.99809 (rank : 103)	NC score	0.052949 (rank : 152)
Query Neighborhood Hits	106	Target Neighborhood Hits	747	Shared Neighborhood Hits	41
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

MCP_MOUSE
θ value	8.99809 (rank : 104)	NC score	0.413439 (rank : 31)
Query Neighborhood Hits	106	Target Neighborhood Hits	79	Shared Neighborhood Hits	57
SwissProt Accessions	O88174, Q9R0R9	Gene names	Cd46, Mcp
Domain Architecture	No domain graphic available
Description	Membrane cofactor protein precursor (CD46 antigen).

TNAP3_HUMAN
θ value	8.99809 (rank : 105)	NC score	0.019710 (rank : 177)
Query Neighborhood Hits	106	Target Neighborhood Hits	58	Shared Neighborhood Hits	5
SwissProt Accessions	P21580, Q5VXQ7, Q9NSR6	Gene names	TNFAIP3
Domain Architecture
Description	Tumor necrosis factor, alpha-induced protein 3 (EC 3.-.-.-) (Putative DNA-binding protein A20) (Zinc finger protein A20).

ZN444_HUMAN
θ value	8.99809 (rank : 106)	NC score	-0.002752 (rank : 187)
Query Neighborhood Hits	106	Target Neighborhood Hits	701	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N0Y2, Q8TEQ9, Q8WU35, Q9NUU1	Gene names	ZNF444, EZF2, ZSCAN17
Domain Architecture
Description	Zinc finger protein 444 (Endothelial zinc finger protein 2) (EZF-2) (Zinc finger and SCAN domain-containing protein 17).

ATRN_HUMAN
θ value	θ > 10 (rank : 107)	NC score	0.060402 (rank : 117)
Query Neighborhood Hits	106	Target Neighborhood Hits	525	Shared Neighborhood Hits	39
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

ATRN_MOUSE
θ value	θ > 10 (rank : 108)	NC score	0.058327 (rank : 124)
Query Neighborhood Hits	106	Target Neighborhood Hits	519	Shared Neighborhood Hits	41
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

BMP1_HUMAN
θ value	θ > 10 (rank : 109)	NC score	0.057467 (rank : 130)
Query Neighborhood Hits	106	Target Neighborhood Hits	233	Shared Neighborhood Hits	30
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

BMP1_MOUSE
θ value	θ > 10 (rank : 110)	NC score	0.057709 (rank : 126)
Query Neighborhood Hits	106	Target Neighborhood Hits	236	Shared Neighborhood Hits	30
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

C1QR1_MOUSE
θ value	θ > 10 (rank : 111)	NC score	0.056270 (rank : 136)
Query Neighborhood Hits	106	Target Neighborhood Hits	342	Shared Neighborhood Hits	38
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

C1RA_MOUSE
θ value	θ > 10 (rank : 112)	NC score	0.074678 (rank : 94)
Query Neighborhood Hits	106	Target Neighborhood Hits	379	Shared Neighborhood Hits	53
SwissProt Accessions	Q8CG16, Q99KI6, Q9ET60	Gene names	C1ra, C1r
Domain Architecture
Description	Complement C1r-A subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-A subcomponent) [Contains: Complement C1r-A subcomponent heavy chain; Complement C1r-A subcomponent light chain].

C1RB_MOUSE
θ value	θ > 10 (rank : 113)	NC score	0.074693 (rank : 93)
Query Neighborhood Hits	106	Target Neighborhood Hits	380	Shared Neighborhood Hits	53
SwissProt Accessions	Q8CFG9	Gene names	C1rb, C1r
Domain Architecture	No domain graphic available
Description	Complement C1r-B subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-B subcomponent) [Contains: Complement C1r-B subcomponent heavy chain; Complement C1r-B subcomponent light chain].

CFAB_HUMAN
θ value	θ > 10 (rank : 114)	NC score	0.207030 (rank : 46)
Query Neighborhood Hits	106	Target Neighborhood Hits	251	Shared Neighborhood Hits	54
SwissProt Accessions	P00751, O15006, Q29944, Q96HX6, Q9BTF5, Q9BX92	Gene names	CFB, BF
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) (Properdin factor B) (Glycine-rich beta glycoprotein) (GBG) (PBF2) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

CO7_HUMAN
θ value	θ > 10 (rank : 115)	NC score	0.174109 (rank : 49)
Query Neighborhood Hits	106	Target Neighborhood Hits	278	Shared Neighborhood Hits	58
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

CRUM1_HUMAN
θ value	θ > 10 (rank : 116)	NC score	0.057237 (rank : 134)
Query Neighborhood Hits	106	Target Neighborhood Hits	457	Shared Neighborhood Hits	44
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

CRUM1_MOUSE
θ value	θ > 10 (rank : 117)	NC score	0.055015 (rank : 143)
Query Neighborhood Hits	106	Target Neighborhood Hits	444	Shared Neighborhood Hits	43
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

CRUM2_HUMAN
θ value	θ > 10 (rank : 118)	NC score	0.055843 (rank : 138)
Query Neighborhood Hits	106	Target Neighborhood Hits	453	Shared Neighborhood Hits	43
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

CSPG2_HUMAN
θ value	θ > 10 (rank : 119)	NC score	0.082258 (rank : 81)
Query Neighborhood Hits	106	Target Neighborhood Hits	681	Shared Neighborhood Hits	60
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

CSPG2_MOUSE
θ value	θ > 10 (rank : 120)	NC score	0.082239 (rank : 82)
Query Neighborhood Hits	106	Target Neighborhood Hits	711	Shared Neighborhood Hits	60
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

CSPG3_HUMAN
θ value	θ > 10 (rank : 121)	NC score	0.093354 (rank : 65)
Query Neighborhood Hits	106	Target Neighborhood Hits	676	Shared Neighborhood Hits	68
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

CSPG3_MOUSE
θ value	θ > 10 (rank : 122)	NC score	0.098295 (rank : 61)
Query Neighborhood Hits	106	Target Neighborhood Hits	657	Shared Neighborhood Hits	67
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

CUBN_HUMAN
θ value	θ > 10 (rank : 123)	NC score	0.085595 (rank : 75)
Query Neighborhood Hits	106	Target Neighborhood Hits	482	Shared Neighborhood Hits	47
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

CUBN_MOUSE
θ value	θ > 10 (rank : 124)	NC score	0.079817 (rank : 88)
Query Neighborhood Hits	106	Target Neighborhood Hits	477	Shared Neighborhood Hits	46
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

DLK_HUMAN
θ value	θ > 10 (rank : 125)	NC score	0.053305 (rank : 149)
Query Neighborhood Hits	106	Target Neighborhood Hits	401	Shared Neighborhood Hits	45
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

DLK_MOUSE
θ value	θ > 10 (rank : 126)	NC score	0.052973 (rank : 151)
Query Neighborhood Hits	106	Target Neighborhood Hits	374	Shared Neighborhood Hits	39
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

DLL1_HUMAN
θ value	θ > 10 (rank : 127)	NC score	0.058905 (rank : 121)
Query Neighborhood Hits	106	Target Neighborhood Hits	455	Shared Neighborhood Hits	40
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

DLL1_MOUSE
θ value	θ > 10 (rank : 128)	NC score	0.058961 (rank : 120)
Query Neighborhood Hits	106	Target Neighborhood Hits	456	Shared Neighborhood Hits	44
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

DLL3_HUMAN
θ value	θ > 10 (rank : 129)	NC score	0.052454 (rank : 154)
Query Neighborhood Hits	106	Target Neighborhood Hits	419	Shared Neighborhood Hits	39
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

DLL3_MOUSE
θ value	θ > 10 (rank : 130)	NC score	0.052779 (rank : 153)
Query Neighborhood Hits	106	Target Neighborhood Hits	399	Shared Neighborhood Hits	40
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

DLL4_HUMAN
θ value	θ > 10 (rank : 131)	NC score	0.051665 (rank : 159)
Query Neighborhood Hits	106	Target Neighborhood Hits	435	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

DLL4_MOUSE
θ value	θ > 10 (rank : 132)	NC score	0.054444 (rank : 144)
Query Neighborhood Hits	106	Target Neighborhood Hits	440	Shared Neighborhood Hits	42
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

DNER_HUMAN
θ value	θ > 10 (rank : 133)	NC score	0.058312 (rank : 125)
Query Neighborhood Hits	106	Target Neighborhood Hits	460	Shared Neighborhood Hits	43
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

DNER_MOUSE
θ value	θ > 10 (rank : 134)	NC score	0.057459 (rank : 131)
Query Neighborhood Hits	106	Target Neighborhood Hits	413	Shared Neighborhood Hits	42
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

EGFL9_HUMAN
θ value	θ > 10 (rank : 135)	NC score	0.053367 (rank : 148)
Query Neighborhood Hits	106	Target Neighborhood Hits	365	Shared Neighborhood Hits	38
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

EGFL9_MOUSE
θ value	θ > 10 (rank : 136)	NC score	0.053014 (rank : 150)
Query Neighborhood Hits	106	Target Neighborhood Hits	379	Shared Neighborhood Hits	37
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

FBLN1_HUMAN
θ value	θ > 10 (rank : 137)	NC score	0.052234 (rank : 155)
Query Neighborhood Hits	106	Target Neighborhood Hits	324	Shared Neighborhood Hits	39
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

FBLN1_MOUSE
θ value	θ > 10 (rank : 138)	NC score	0.057580 (rank : 127)
Query Neighborhood Hits	106	Target Neighborhood Hits	329	Shared Neighborhood Hits	39
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

FBLN2_HUMAN
θ value	θ > 10 (rank : 139)	NC score	0.055476 (rank : 141)
Query Neighborhood Hits	106	Target Neighborhood Hits	392	Shared Neighborhood Hits	40
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

FBLN2_MOUSE
θ value	θ > 10 (rank : 140)	NC score	0.057350 (rank : 132)
Query Neighborhood Hits	106	Target Neighborhood Hits	505	Shared Neighborhood Hits	45
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

FBN1_HUMAN
θ value	θ > 10 (rank : 141)	NC score	0.065292 (rank : 108)
Query Neighborhood Hits	106	Target Neighborhood Hits	557	Shared Neighborhood Hits	49
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

FBN2_HUMAN
θ value	θ > 10 (rank : 142)	NC score	0.061554 (rank : 114)
Query Neighborhood Hits	106	Target Neighborhood Hits	560	Shared Neighborhood Hits	49
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN2_MOUSE
θ value	θ > 10 (rank : 143)	NC score	0.064298 (rank : 109)
Query Neighborhood Hits	106	Target Neighborhood Hits	549	Shared Neighborhood Hits	53
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

FBN3_HUMAN
θ value	θ > 10 (rank : 144)	NC score	0.060443 (rank : 116)
Query Neighborhood Hits	106	Target Neighborhood Hits	543	Shared Neighborhood Hits	46
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

GABR1_HUMAN
θ value	θ > 10 (rank : 145)	NC score	0.130523 (rank : 55)
Query Neighborhood Hits	106	Target Neighborhood Hits	142	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UBS5, O95375, O95468, O95975, O96022, Q86W60, Q9UQQ0	Gene names	GABBR1, GPRC3A
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

GABR1_MOUSE
θ value	θ > 10 (rank : 146)	NC score	0.129719 (rank : 56)
Query Neighborhood Hits	106	Target Neighborhood Hits	139	Shared Neighborhood Hits	42
SwissProt Accessions	Q9WV18, Q9WU48, Q9WV15, Q9WV16, Q9WV17	Gene names	Gabbr1
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

IL2RA_HUMAN
θ value	θ > 10 (rank : 147)	NC score	0.064146 (rank : 110)
Query Neighborhood Hits	106	Target Neighborhood Hits	32	Shared Neighborhood Hits	19
SwissProt Accessions	P01589	Gene names	IL2RA
Domain Architecture
Description	Interleukin-2 receptor alpha chain precursor (IL-2 receptor alpha subunit) (IL-2-RA) (IL2-RA) (p55) (TAC antigen) (CD25 antigen).

JAG2_HUMAN
θ value	θ > 10 (rank : 148)	NC score	0.060647 (rank : 115)
Query Neighborhood Hits	106	Target Neighborhood Hits	491	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

JAG2_MOUSE
θ value	θ > 10 (rank : 149)	NC score	0.061699 (rank : 113)
Query Neighborhood Hits	106	Target Neighborhood Hits	504	Shared Neighborhood Hits	49
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

K0247_HUMAN
θ value	θ > 10 (rank : 150)	NC score	0.134363 (rank : 53)
Query Neighborhood Hits	106	Target Neighborhood Hits	42	Shared Neighborhood Hits	28
SwissProt Accessions	Q92537	Gene names	KIAA0247
Domain Architecture	No domain graphic available
Description	Protein KIAA0247 precursor.

KR101_HUMAN
θ value	θ > 10 (rank : 151)	NC score	0.072800 (rank : 97)
Query Neighborhood Hits	106	Target Neighborhood Hits	261	Shared Neighborhood Hits	31
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

KR102_HUMAN
θ value	θ > 10 (rank : 152)	NC score	0.077774 (rank : 91)
Query Neighborhood Hits	106	Target Neighborhood Hits	264	Shared Neighborhood Hits	31
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

KR104_HUMAN
θ value	θ > 10 (rank : 153)	NC score	0.087772 (rank : 68)
Query Neighborhood Hits	106	Target Neighborhood Hits	313	Shared Neighborhood Hits	32
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

KR106_HUMAN
θ value	θ > 10 (rank : 154)	NC score	0.074028 (rank : 95)
Query Neighborhood Hits	106	Target Neighborhood Hits	347	Shared Neighborhood Hits	36
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

KR107_HUMAN
θ value	θ > 10 (rank : 155)	NC score	0.088714 (rank : 67)
Query Neighborhood Hits	106	Target Neighborhood Hits	330	Shared Neighborhood Hits	33
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

KR108_HUMAN
θ value	θ > 10 (rank : 156)	NC score	0.064121 (rank : 111)
Query Neighborhood Hits	106	Target Neighborhood Hits	226	Shared Neighborhood Hits	30
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

KR109_HUMAN
θ value	θ > 10 (rank : 157)	NC score	0.071850 (rank : 101)
Query Neighborhood Hits	106	Target Neighborhood Hits	226	Shared Neighborhood Hits	27
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

KR10B_HUMAN
θ value	θ > 10 (rank : 158)	NC score	0.072129 (rank : 99)
Query Neighborhood Hits	106	Target Neighborhood Hits	269	Shared Neighborhood Hits	26
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

KR10C_HUMAN
θ value	θ > 10 (rank : 159)	NC score	0.056102 (rank : 137)
Query Neighborhood Hits	106	Target Neighborhood Hits	219	Shared Neighborhood Hits	25
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

LAMA5_HUMAN
θ value	θ > 10 (rank : 160)	NC score	0.052232 (rank : 156)
Query Neighborhood Hits	106	Target Neighborhood Hits	976	Shared Neighborhood Hits	44
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LTB1L_HUMAN
θ value	θ > 10 (rank : 161)	NC score	0.054079 (rank : 146)
Query Neighborhood Hits	106	Target Neighborhood Hits	553	Shared Neighborhood Hits	49
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
θ value	θ > 10 (rank : 162)	NC score	0.053904 (rank : 147)
Query Neighborhood Hits	106	Target Neighborhood Hits	502	Shared Neighborhood Hits	48
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTBP2_HUMAN
θ value	θ > 10 (rank : 163)	NC score	0.066739 (rank : 105)
Query Neighborhood Hits	106	Target Neighborhood Hits	552	Shared Neighborhood Hits	56
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LTBP3_HUMAN
θ value	θ > 10 (rank : 164)	NC score	0.057512 (rank : 129)
Query Neighborhood Hits	106	Target Neighborhood Hits	502	Shared Neighborhood Hits	52
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

LTBP3_MOUSE
θ value	θ > 10 (rank : 165)	NC score	0.059488 (rank : 119)
Query Neighborhood Hits	106	Target Neighborhood Hits	475	Shared Neighborhood Hits	54
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

LTBP4_MOUSE
θ value	θ > 10 (rank : 166)	NC score	0.068738 (rank : 103)
Query Neighborhood Hits	106	Target Neighborhood Hits	607	Shared Neighborhood Hits	47
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

MASP1_HUMAN
θ value	θ > 10 (rank : 167)	NC score	0.092255 (rank : 66)
Query Neighborhood Hits	106	Target Neighborhood Hits	369	Shared Neighborhood Hits	60
SwissProt Accessions	P48740, O95570, Q9UF09	Gene names	MASP1, CRARF, CRARF1, PRSS5
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) (Mannose-binding protein- associated serine protease) (MASP-1) [Contains: Complement-activating component of Ra-reactive factor heavy chain; Complement-activating component of Ra-reactive factor light chain].

MASP1_MOUSE
θ value	θ > 10 (rank : 168)	NC score	0.085035 (rank : 76)
Query Neighborhood Hits	106	Target Neighborhood Hits	364	Shared Neighborhood Hits	59
SwissProt Accessions	P98064	Gene names	Masp1, Crarf
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) [Contains: Complement- activating component of Ra-reactive factor heavy chain; Complement- activating component of Ra-reactive factor light chain].

MASP2_HUMAN
θ value	θ > 10 (rank : 169)	NC score	0.101836 (rank : 60)
Query Neighborhood Hits	106	Target Neighborhood Hits	364	Shared Neighborhood Hits	59
SwissProt Accessions	O00187, O75754, Q5TEQ5, Q5TER0, Q96QG4, Q9BZH0, Q9H498, Q9H499, Q9UBP3, Q9ULC7, Q9UMV3, Q9Y270	Gene names	MASP2
Domain Architecture
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

MCP_HUMAN
θ value	θ > 10 (rank : 170)	NC score	0.402256 (rank : 34)
Query Neighborhood Hits	106	Target Neighborhood Hits	82	Shared Neighborhood Hits	54
SwissProt Accessions	P15529, Q15429, Q53GV9, Q5HY94, Q5VWS6, Q5VWS7, Q5VWS8, Q5VWS9, Q5VWT0, Q5VWT1, Q5VWT2, Q6N0A1, Q7Z3R5, Q9NNW2, Q9NNW3, Q9NNW4	Gene names	CD46, MCP
Domain Architecture
Description	Membrane cofactor protein precursor (Trophoblast leukocyte common antigen) (TLX) (CD46 antigen).

MEGF6_HUMAN
θ value	θ > 10 (rank : 171)	NC score	0.086334 (rank : 72)
Query Neighborhood Hits	106	Target Neighborhood Hits	671	Shared Neighborhood Hits	53
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

PERT_HUMAN
θ value	θ > 10 (rank : 172)	NC score	0.085880 (rank : 73)
Query Neighborhood Hits	106	Target Neighborhood Hits	221	Shared Neighborhood Hits	56
SwissProt Accessions	P07202, P09934, P09935, Q8IUL0, Q8NF94, Q8NF95, Q8NF96, Q8NF97, Q8TCI9	Gene names	TPO
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

PERT_MOUSE
θ value	θ > 10 (rank : 173)	NC score	0.095373 (rank : 63)
Query Neighborhood Hits	106	Target Neighborhood Hits	221	Shared Neighborhood Hits	57
SwissProt Accessions	P35419, Q8C8B1	Gene names	Tpo
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

SCUB3_HUMAN
θ value	θ > 10 (rank : 174)	NC score	0.055653 (rank : 139)
Query Neighborhood Hits	106	Target Neighborhood Hits	428	Shared Neighborhood Hits	43
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SCUB3_MOUSE
θ value	θ > 10 (rank : 175)	NC score	0.054356 (rank : 145)
Query Neighborhood Hits	106	Target Neighborhood Hits	442	Shared Neighborhood Hits	44
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SREC2_HUMAN
θ value	θ > 10 (rank : 176)	NC score	0.065954 (rank : 106)
Query Neighborhood Hits	106	Target Neighborhood Hits	645	Shared Neighborhood Hits	39
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

SREC2_MOUSE
θ value	θ > 10 (rank : 177)	NC score	0.082829 (rank : 80)
Query Neighborhood Hits	106	Target Neighborhood Hits	605	Shared Neighborhood Hits	38
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

SREC_HUMAN
θ value	θ > 10 (rank : 178)	NC score	0.063494 (rank : 112)
Query Neighborhood Hits	106	Target Neighborhood Hits	645	Shared Neighborhood Hits	39
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

STAB2_MOUSE
θ value	θ > 10 (rank : 179)	NC score	0.056654 (rank : 135)
Query Neighborhood Hits	106	Target Neighborhood Hits	528	Shared Neighborhood Hits	47
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

SUSD2_HUMAN
θ value	θ > 10 (rank : 180)	NC score	0.170504 (rank : 50)
Query Neighborhood Hits	106	Target Neighborhood Hits	99	Shared Neighborhood Hits	53
SwissProt Accessions	Q9UGT4, Q9H5Y6	Gene names	SUSD2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

SUSD2_MOUSE
θ value	θ > 10 (rank : 181)	NC score	0.182206 (rank : 48)
Query Neighborhood Hits	106	Target Neighborhood Hits	104	Shared Neighborhood Hits	54
SwissProt Accessions	Q9DBX3, Q8BY19, Q8BYN0, Q8BYZ3, Q8BYZ9, Q8BZQ4, Q8C179	Gene names	Susd2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

SUSD3_HUMAN
θ value	θ > 10 (rank : 182)	NC score	0.087451 (rank : 71)
Query Neighborhood Hits	106	Target Neighborhood Hits	32	Shared Neighborhood Hits	22
SwissProt Accessions	Q96L08, Q49AA6, Q6UXV7	Gene names	SUSD3, UNQ9387/PRO34275
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 3.

SUSD3_MOUSE
θ value	θ > 10 (rank : 183)	NC score	0.155971 (rank : 52)
Query Neighborhood Hits	106	Target Neighborhood Hits	39	Shared Neighborhood Hits	28
SwissProt Accessions	Q9D176, Q80XL5, Q9CYV1, Q9DA86	Gene names	Susd3
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 3.

TLL1_HUMAN
θ value	θ > 10 (rank : 184)	NC score	0.057298 (rank : 133)
Query Neighborhood Hits	106	Target Neighborhood Hits	236	Shared Neighborhood Hits	29
SwissProt Accessions	O43897, Q96AN3, Q9NQS4	Gene names	TLL1, TLL
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-).

TLL1_MOUSE
θ value	θ > 10 (rank : 185)	NC score	0.059691 (rank : 118)
Query Neighborhood Hits	106	Target Neighborhood Hits	237	Shared Neighborhood Hits	30
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

TLL2_HUMAN
θ value	θ > 10 (rank : 186)	NC score	0.057522 (rank : 128)
Query Neighborhood Hits	106	Target Neighborhood Hits	241	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Y6L7, Q6PJN5, Q9UQ00	Gene names	TLL2, KIAA0932
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

TLL2_MOUSE
θ value	θ > 10 (rank : 187)	NC score	0.058641 (rank : 123)
Query Neighborhood Hits	106	Target Neighborhood Hits	240	Shared Neighborhood Hits	32
SwissProt Accessions	Q9WVM6	Gene names	Tll2
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

ZAN_MOUSE
θ value	θ > 10 (rank : 188)	NC score	0.080228 (rank : 85)
Query Neighborhood Hits	106	Target Neighborhood Hits	808	Shared Neighborhood Hits	53
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

Hits sorted by NC score

PAP2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	106	Target Neighborhood Hits	106	Shared Neighborhood Hits	106
SwissProt Accessions	Q9BXP8, Q96PH7, Q96PH8, Q9H4C9	Gene names	PAPPA2
Domain Architecture	No domain graphic available
Description	Pappalysin-2 precursor (EC 3.4.24.-) (Pregnancy-associated plasma protein-A2) (PAPP-A2) (Pregnancy-associated plasma protein-E1) (PAPP- E).

PAPPA_MOUSE
NC score	0.951476 (rank : 2)	θ value	0 (rank : 3)
Query Neighborhood Hits	106	Target Neighborhood Hits	153	Shared Neighborhood Hits	69
SwissProt Accessions	Q8R4K8, Q80VW3, Q80YY1, Q8K423, Q8R4K7, Q9ES06, Q9JK57	Gene names	Pappa
Domain Architecture	No domain graphic available
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

PAPPA_HUMAN
NC score	0.947119 (rank : 3)	θ value	0 (rank : 2)
Query Neighborhood Hits	106	Target Neighborhood Hits	161	Shared Neighborhood Hits	73
SwissProt Accessions	Q13219, Q08371, Q68G52, Q9UDK7	Gene names	PAPPA
Domain Architecture
Description	Pappalysin-1 precursor (EC 3.4.24.79) (Pregnancy-associated plasma protein-A) (PAPP-A) (Insulin-like growth factor-dependent IGF-binding protein 4 protease) (IGF-dependent IGFBP-4 protease) (IGFBP-4ase).

DAF2_MOUSE
NC score	0.574623 (rank : 4)	θ value	5.8054e-15 (rank : 4)
Query Neighborhood Hits	106	Target Neighborhood Hits	114	Shared Neighborhood Hits	55
SwissProt Accessions	Q61476	Gene names	Cd55b, Daf2
Domain Architecture
Description	Complement decay-accelerating factor transmembrane isoform precursor (DAF-TM) (CD55 antigen).

DAF1_MOUSE
NC score	0.567521 (rank : 5)	θ value	2.20605e-14 (rank : 5)
Query Neighborhood Hits	106	Target Neighborhood Hits	204	Shared Neighborhood Hits	58
SwissProt Accessions	Q61475, P97732, Q61397	Gene names	Cd55a, Daf1
Domain Architecture
Description	Complement decay-accelerating factor, GPI-anchored precursor (DAF-GPI) (CD55 antigen).

DAF_HUMAN
NC score	0.555361 (rank : 6)	θ value	1.58096e-12 (rank : 7)
Query Neighborhood Hits	106	Target Neighborhood Hits	97	Shared Neighborhood Hits	54
SwissProt Accessions	P08174, P09679, P78361	Gene names	CD55, CR, DAF
Domain Architecture
Description	Complement decay-accelerating factor precursor (CD55 antigen).

CR1_HUMAN
NC score	0.513192 (rank : 7)	θ value	5.62301e-10 (rank : 11)
Query Neighborhood Hits	106	Target Neighborhood Hits	108	Shared Neighborhood Hits	58
SwissProt Accessions	P17927, Q16745, Q9UQV2	Gene names	CR1, C3BR
Domain Architecture
Description	Complement receptor type 1 precursor (C3b/C4b receptor) (CD35 antigen).

CR2_HUMAN
NC score	0.505508 (rank : 8)	θ value	1.80886e-08 (rank : 16)
Query Neighborhood Hits	106	Target Neighborhood Hits	89	Shared Neighborhood Hits	57
SwissProt Accessions	P20023, Q13866, Q14212	Gene names	CR2, C3DR
Domain Architecture
Description	Complement receptor type 2 precursor (Cr2) (Complement C3d receptor) (Epstein-Barr virus receptor) (EBV receptor) (CD21 antigen).

ZP3R_MOUSE
NC score	0.504948 (rank : 9)	θ value	7.59969e-07 (rank : 18)
Query Neighborhood Hits	106	Target Neighborhood Hits	81	Shared Neighborhood Hits	55
SwissProt Accessions	Q60736	Gene names	Zp3r, Sp56
Domain Architecture
Description	Zona pellucida sperm-binding protein 3 receptor precursor (Sperm fertilization protein 56) (sp56).

CR2_MOUSE
NC score	0.504306 (rank : 10)	θ value	2.79066e-09 (rank : 15)
Query Neighborhood Hits	106	Target Neighborhood Hits	101	Shared Neighborhood Hits	56
SwissProt Accessions	P19070	Gene names	Cr2
Domain Architecture
Description	Complement receptor type 2 precursor (Cr2) (Complement C3d receptor) (CD21 antigen).

C4BP_HUMAN
NC score	0.495982 (rank : 11)	θ value	4.1701e-05 (rank : 25)
Query Neighborhood Hits	106	Target Neighborhood Hits	92	Shared Neighborhood Hits	58
SwissProt Accessions	P04003	Gene names	C4BPA, C4BP
Domain Architecture
Description	C4b-binding protein alpha chain precursor (C4bp) (Proline-rich protein) (PRP).

CFAH_MOUSE
NC score	0.495166 (rank : 12)	θ value	2.13673e-09 (rank : 14)
Query Neighborhood Hits	106	Target Neighborhood Hits	112	Shared Neighborhood Hits	59
SwissProt Accessions	P06909	Gene names	Cfh, Hf1
Domain Architecture
Description	Complement factor H precursor (Protein beta-1-H).

LYAM3_HUMAN
NC score	0.494863 (rank : 13)	θ value	1.86753e-13 (rank : 6)
Query Neighborhood Hits	106	Target Neighborhood Hits	378	Shared Neighborhood Hits	76
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

APOH_MOUSE
NC score	0.490783 (rank : 14)	θ value	0.00020696 (rank : 32)
Query Neighborhood Hits	106	Target Neighborhood Hits	74	Shared Neighborhood Hits	53
SwissProt Accessions	Q01339	Gene names	Apoh, B2gp1
Domain Architecture
Description	Beta-2-glycoprotein 1 precursor (Beta-2-glycoprotein I) (Apolipoprotein H) (Apo-H) (B2GPI) (Beta(2)GPI) (Activated protein C- binding protein) (APC inhibitor).

CRRY_MOUSE
NC score	0.484449 (rank : 15)	θ value	0.125558 (rank : 54)
Query Neighborhood Hits	106	Target Neighborhood Hits	84	Shared Neighborhood Hits	55
SwissProt Accessions	Q64735, Q3TV30, Q58E68, Q61447, Q61449, Q8CF59, Q8K328	Gene names	Crry, Cry
Domain Architecture	No domain graphic available
Description	Complement regulatory protein Crry precursor (Protein p65).

C4BP_MOUSE
NC score	0.483562 (rank : 16)	θ value	5.44631e-05 (rank : 29)
Query Neighborhood Hits	106	Target Neighborhood Hits	91	Shared Neighborhood Hits	55
SwissProt Accessions	P08607	Gene names	C4bpa, C4bp
Domain Architecture
Description	C4b-binding protein precursor (C4bp).

LYAM3_MOUSE
NC score	0.482755 (rank : 17)	θ value	3.89403e-11 (rank : 10)
Query Neighborhood Hits	106	Target Neighborhood Hits	390	Shared Neighborhood Hits	78
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

LYAM2_HUMAN
NC score	0.481532 (rank : 18)	θ value	3.52202e-12 (rank : 8)
Query Neighborhood Hits	106	Target Neighborhood Hits	394	Shared Neighborhood Hits	77
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

SRPX_HUMAN
NC score	0.480382 (rank : 19)	θ value	1.09739e-05 (rank : 23)
Query Neighborhood Hits	106	Target Neighborhood Hits	69	Shared Neighborhood Hits	44
SwissProt Accessions	P78539, Q99652, Q99913	Gene names	SRPX, ETX1
Domain Architecture
Description	Sushi repeat-containing protein SRPX precursor.

CFAH_HUMAN
NC score	0.480086 (rank : 20)	θ value	2.13673e-09 (rank : 13)
Query Neighborhood Hits	106	Target Neighborhood Hits	101	Shared Neighborhood Hits	58
SwissProt Accessions	P08603, P78435, Q14570, Q38G77, Q5TFM3, Q8N708, Q9NU86	Gene names	CFH, HF, HF1
Domain Architecture
Description	Complement factor H precursor (H factor 1).

SRPX_MOUSE
NC score	0.480026 (rank : 21)	θ value	9.29e-05 (rank : 31)
Query Neighborhood Hits	106	Target Neighborhood Hits	75	Shared Neighborhood Hits	46
SwissProt Accessions	Q9R0M3, Q9R0M2	Gene names	Srpx
Domain Architecture	No domain graphic available
Description	Sushi-repeat-containing protein SRPX precursor (DRS protein).

C4BB_HUMAN
NC score	0.472784 (rank : 22)	θ value	5.44631e-05 (rank : 28)
Query Neighborhood Hits	106	Target Neighborhood Hits	77	Shared Neighborhood Hits	51
SwissProt Accessions	P20851	Gene names	C4BPB
Domain Architecture
Description	C4b-binding protein beta chain precursor.

F13B_MOUSE
NC score	0.472587 (rank : 23)	θ value	2.21117e-06 (rank : 21)
Query Neighborhood Hits	106	Target Neighborhood Hits	93	Shared Neighborhood Hits	58
SwissProt Accessions	Q07968	Gene names	F13b, Cf13b
Domain Architecture
Description	Coagulation factor XIII B chain precursor (Protein-glutamine gamma- glutamyltransferase B chain) (Transglutaminase B chain).

LYAM2_MOUSE
NC score	0.471087 (rank : 24)	θ value	1.74796e-11 (rank : 9)
Query Neighborhood Hits	106	Target Neighborhood Hits	420	Shared Neighborhood Hits	78
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

F13B_HUMAN
NC score	0.470038 (rank : 25)	θ value	4.1701e-05 (rank : 26)
Query Neighborhood Hits	106	Target Neighborhood Hits	84	Shared Neighborhood Hits	51
SwissProt Accessions	P05160	Gene names	F13B
Domain Architecture
Description	Coagulation factor XIII B chain precursor (Protein-glutamine gamma- glutamyltransferase B chain) (Transglutaminase B chain) (Fibrin- stabilizing factor B subunit).

SUSD4_HUMAN
NC score	0.449588 (rank : 26)	θ value	4.1701e-05 (rank : 27)
Query Neighborhood Hits	106	Target Neighborhood Hits	88	Shared Neighborhood Hits	49
SwissProt Accessions	Q5VX71, Q6UX62, Q9BSR0, Q9NWG0	Gene names	SUSD4
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 4 precursor.

APOH_HUMAN
NC score	0.442473 (rank : 27)	θ value	0.163984 (rank : 56)
Query Neighborhood Hits	106	Target Neighborhood Hits	75	Shared Neighborhood Hits	53
SwissProt Accessions	P02749, Q9UCN7	Gene names	APOH, B2G1
Domain Architecture
Description	Beta-2-glycoprotein 1 precursor (Beta-2-glycoprotein I) (Apolipoprotein H) (Apo-H) (B2GPI) (Beta(2)GPI) (Activated protein C- binding protein) (APC inhibitor) (Anticardiolipin cofactor).

FHR5_HUMAN
NC score	0.432495 (rank : 28)	θ value	0.0736092 (rank : 44)
Query Neighborhood Hits	106	Target Neighborhood Hits	77	Shared Neighborhood Hits	52
SwissProt Accessions	Q9BXR6	Gene names	CFHL5, FHR5
Domain Architecture
Description	Complement factor H-related protein 5 precursor (FHR-5).

FHR1_HUMAN
NC score	0.430880 (rank : 29)	θ value	0.0563607 (rank : 42)
Query Neighborhood Hits	106	Target Neighborhood Hits	80	Shared Neighborhood Hits	53
SwissProt Accessions	Q03591, Q9UJ17	Gene names	CFHL1, CFHL, FHR1, HFL1
Domain Architecture
Description	Complement factor H-related protein 1 precursor (FHR-1) (H factor-like protein 1) (H-factor-like 1) (H36).

SUSD4_MOUSE
NC score	0.425952 (rank : 30)	θ value	0.00035302 (rank : 33)
Query Neighborhood Hits	106	Target Neighborhood Hits	122	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BH32, Q8VC43	Gene names	Susd4
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 4 precursor.

MCP_MOUSE
NC score	0.413439 (rank : 31)	θ value	8.99809 (rank : 104)
Query Neighborhood Hits	106	Target Neighborhood Hits	79	Shared Neighborhood Hits	57
SwissProt Accessions	O88174, Q9R0R9	Gene names	Cd46, Mcp
Domain Architecture	No domain graphic available
Description	Membrane cofactor protein precursor (CD46 antigen).

FHR2_HUMAN
NC score	0.413320 (rank : 32)	θ value	0.00869519 (rank : 37)
Query Neighborhood Hits	106	Target Neighborhood Hits	63	Shared Neighborhood Hits	47
SwissProt Accessions	P36980, Q14310	Gene names	CFHL2, FHR2, HFL3
Domain Architecture
Description	Complement factor H-related protein 2 precursor (FHR-2) (H factor-like protein 2) (H factor-like 3) (DDESK59).

FHR3_HUMAN
NC score	0.410973 (rank : 33)	θ value	3.19293e-05 (rank : 24)
Query Neighborhood Hits	106	Target Neighborhood Hits	74	Shared Neighborhood Hits	50
SwissProt Accessions	Q02985, Q9UJ16	Gene names	CFHL3, FHR3
Domain Architecture
Description	Complement factor H-related protein 3 precursor (FHR-3) (H factor-like protein 3) (DOWN16).

MCP_HUMAN
NC score	0.402256 (rank : 34)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	106	Target Neighborhood Hits	82	Shared Neighborhood Hits	54
SwissProt Accessions	P15529, Q15429, Q53GV9, Q5HY94, Q5VWS6, Q5VWS7, Q5VWS8, Q5VWS9, Q5VWT0, Q5VWT1, Q5VWT2, Q6N0A1, Q7Z3R5, Q9NNW2, Q9NNW3, Q9NNW4	Gene names	CD46, MCP
Domain Architecture
Description	Membrane cofactor protein precursor (Trophoblast leukocyte common antigen) (TLX) (CD46 antigen).

FHR4_HUMAN
NC score	0.401258 (rank : 35)	θ value	4.92598e-06 (rank : 22)
Query Neighborhood Hits	106	Target Neighborhood Hits	75	Shared Neighborhood Hits	52
SwissProt Accessions	Q92496, Q9UJY6	Gene names	CFHL4, FHR4
Domain Architecture
Description	Complement factor H-related protein 4 precursor (FHR-4).

CSMD1_MOUSE
NC score	0.400338 (rank : 36)	θ value	1.63604e-09 (rank : 12)
Query Neighborhood Hits	106	Target Neighborhood Hits	193	Shared Neighborhood Hits	61
SwissProt Accessions	Q923L3, Q8BUV1, Q8BYQ3	Gene names	Csmd1
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

CSMD1_HUMAN
NC score	0.396419 (rank : 37)	θ value	2.21117e-06 (rank : 20)
Query Neighborhood Hits	106	Target Neighborhood Hits	176	Shared Neighborhood Hits	61
SwissProt Accessions	Q96PZ7, Q96QU9, Q96RM4	Gene names	CSMD1, KIAA1890
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

CSMD3_HUMAN
NC score	0.395823 (rank : 38)	θ value	3.41135e-07 (rank : 17)
Query Neighborhood Hits	106	Target Neighborhood Hits	199	Shared Neighborhood Hits	62
SwissProt Accessions	Q7Z407, Q96PZ3	Gene names	CSMD3, KIAA1894
Domain Architecture
Description	CUB and sushi domain-containing protein 3 precursor (CUB and sushi multiple domains protein 3).

CSMD2_HUMAN
NC score	0.386791 (rank : 39)	θ value	9.92553e-07 (rank : 19)
Query Neighborhood Hits	106	Target Neighborhood Hits	188	Shared Neighborhood Hits	59
SwissProt Accessions	Q7Z408, Q5VT59, Q8N963, Q96Q03, Q9H4V7, Q9H4V8, Q9H4V9, Q9H4W0, Q9H4W1, Q9H4W2, Q9H4W3, Q9H4W4, Q9HCY5, Q9HCY6, Q9HCY7	Gene names	CSMD2, KIAA1884
Domain Architecture
Description	CUB and sushi domain-containing protein 2 (CUB and sushi multiple domains protein 2).

LYAM1_MOUSE
NC score	0.370350 (rank : 40)	θ value	0.00228821 (rank : 35)
Query Neighborhood Hits	106	Target Neighborhood Hits	332	Shared Neighborhood Hits	64
SwissProt Accessions	P18337	Gene names	Sell, Lnhr, Ly-22
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Lymphocyte antigen 22) (Ly-22) (Lymphocyte surface MEL-14 antigen) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

LYAM1_HUMAN
NC score	0.355973 (rank : 41)	θ value	0.0961366 (rank : 52)
Query Neighborhood Hits	106	Target Neighborhood Hits	315	Shared Neighborhood Hits	64
SwissProt Accessions	P14151, P15023	Gene names	SELL, LNHR, LYAM1
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte surface antigen Leu-8) (TQ1) (gp90-MEL) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

SEZ6L_HUMAN
NC score	0.324446 (rank : 42)	θ value	5.27518 (rank : 90)
Query Neighborhood Hits	106	Target Neighborhood Hits	289	Shared Neighborhood Hits	55
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

CO2_HUMAN
NC score	0.252878 (rank : 43)	θ value	0.000786445 (rank : 34)
Query Neighborhood Hits	106	Target Neighborhood Hits	258	Shared Neighborhood Hits	53
SwissProt Accessions	P06681, O19694, Q13904	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

SUSD1_HUMAN
NC score	0.240918 (rank : 44)	θ value	5.44631e-05 (rank : 30)
Query Neighborhood Hits	106	Target Neighborhood Hits	285	Shared Neighborhood Hits	62
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

CFAB_MOUSE
NC score	0.211648 (rank : 45)	θ value	5.27518 (rank : 88)
Query Neighborhood Hits	106	Target Neighborhood Hits	262	Shared Neighborhood Hits	54
SwissProt Accessions	P04186	Gene names	Cfb, Bf, H2-Bf
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

CFAB_HUMAN
NC score	0.207030 (rank : 46)	θ value	θ > 10 (rank : 114)
Query Neighborhood Hits	106	Target Neighborhood Hits	251	Shared Neighborhood Hits	54
SwissProt Accessions	P00751, O15006, Q29944, Q96HX6, Q9BTF5, Q9BX92	Gene names	CFB, BF
Domain Architecture
Description	Complement factor B precursor (EC 3.4.21.47) (C3/C5 convertase) (Properdin factor B) (Glycine-rich beta glycoprotein) (GBG) (PBF2) [Contains: Complement factor B Ba fragment; Complement factor B Bb fragment].

CO2_MOUSE
NC score	0.192992 (rank : 47)	θ value	1.38821 (rank : 70)
Query Neighborhood Hits	106	Target Neighborhood Hits	250	Shared Neighborhood Hits	53
SwissProt Accessions	P21180	Gene names	C2
Domain Architecture
Description	Complement C2 precursor (EC 3.4.21.43) (C3/C5 convertase) [Contains: Complement C2b fragment; Complement C2a fragment].

SUSD2_MOUSE
NC score	0.182206 (rank : 48)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	106	Target Neighborhood Hits	104	Shared Neighborhood Hits	54
SwissProt Accessions	Q9DBX3, Q8BY19, Q8BYN0, Q8BYZ3, Q8BYZ9, Q8BZQ4, Q8C179	Gene names	Susd2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

CO7_HUMAN
NC score	0.174109 (rank : 49)	θ value	θ > 10 (rank : 115)
Query Neighborhood Hits	106	Target Neighborhood Hits	278	Shared Neighborhood Hits	58
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

SUSD2_HUMAN
NC score	0.170504 (rank : 50)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	106	Target Neighborhood Hits	99	Shared Neighborhood Hits	53
SwissProt Accessions	Q9UGT4, Q9H5Y6	Gene names	SUSD2
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 2 precursor.

CO6_HUMAN
NC score	0.166071 (rank : 51)	θ value	8.99809 (rank : 102)
Query Neighborhood Hits	106	Target Neighborhood Hits	331	Shared Neighborhood Hits	66
SwissProt Accessions	P13671	Gene names	C6
Domain Architecture
Description	Complement component C6 precursor.

SUSD3_MOUSE
NC score	0.155971 (rank : 52)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	106	Target Neighborhood Hits	39	Shared Neighborhood Hits	28
SwissProt Accessions	Q9D176, Q80XL5, Q9CYV1, Q9DA86	Gene names	Susd3
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 3.

K0247_HUMAN
NC score	0.134363 (rank : 53)	θ value	θ > 10 (rank : 150)
Query Neighborhood Hits	106	Target Neighborhood Hits	42	Shared Neighborhood Hits	28
SwissProt Accessions	Q92537	Gene names	KIAA0247
Domain Architecture	No domain graphic available
Description	Protein KIAA0247 precursor.

GNPTA_MOUSE
NC score	0.132298 (rank : 54)	θ value	0.0736092 (rank : 45)
Query Neighborhood Hits	106	Target Neighborhood Hits	47	Shared Neighborhood Hits	13
SwissProt Accessions	Q69ZN6, Q3U3K6, Q3US34	Gene names	Gnptab, Gnpta, Kiaa1208
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphotransferase subunits alpha/beta precursor (EC 2.7.8.17) (GlcNAc-1-phosphotransferase alpha/beta subunits) (UDP- N-acetylglucosamine-1-phosphotransferase alpha/beta subunits) (Stealth protein GNPTAB) [Contains: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta].

GABR1_HUMAN
NC score	0.130523 (rank : 55)	θ value	θ > 10 (rank : 145)
Query Neighborhood Hits	106	Target Neighborhood Hits	142	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UBS5, O95375, O95468, O95975, O96022, Q86W60, Q9UQQ0	Gene names	GABBR1, GPRC3A
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

GABR1_MOUSE
NC score	0.129719 (rank : 56)	θ value	θ > 10 (rank : 146)
Query Neighborhood Hits	106	Target Neighborhood Hits	139	Shared Neighborhood Hits	42
SwissProt Accessions	Q9WV18, Q9WU48, Q9WV15, Q9WV16, Q9WV17	Gene names	Gabbr1
Domain Architecture
Description	Gamma-aminobutyric acid type B receptor, subunit 1 precursor (GABA-B receptor 1) (GABA-B-R1) (Gb1).

GNPTA_HUMAN
NC score	0.123810 (rank : 57)	θ value	0.21417 (rank : 58)
Query Neighborhood Hits	106	Target Neighborhood Hits	43	Shared Neighborhood Hits	13
SwissProt Accessions	Q3T906, Q3ZQK2, Q6IPW5, Q86TQ2, Q96N13, Q9ULL2	Gene names	GNPTAB, GNPTA, KIAA1208
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphotransferase subunits alpha/beta precursor (EC 2.7.8.17) (GlcNAc-1-phosphotransferase alpha/beta subunits) (UDP- N-acetylglucosamine-1-phosphotransferase alpha/beta subunits) (Stealth protein GNPTAB) [Contains: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta].

MASP2_MOUSE
NC score	0.122173 (rank : 58)	θ value	0.365318 (rank : 62)
Query Neighborhood Hits	106	Target Neighborhood Hits	382	Shared Neighborhood Hits	61
SwissProt Accessions	Q91WP0, Q9QXA4, Q9QXD2, Q9QXD5, Q9Z338	Gene names	Masp2
Domain Architecture	No domain graphic available
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

C1S_HUMAN
NC score	0.111049 (rank : 59)	θ value	6.88961 (rank : 93)
Query Neighborhood Hits	106	Target Neighborhood Hits	359	Shared Neighborhood Hits	57
SwissProt Accessions	P09871, Q9UCU7, Q9UCU8, Q9UCU9, Q9UCV0, Q9UCV1, Q9UCV2, Q9UCV3, Q9UCV4, Q9UCV5, Q9UM14	Gene names	C1S
Domain Architecture
Description	Complement C1s subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s subcomponent heavy chain; Complement C1s subcomponent light chain].

MASP2_HUMAN
NC score	0.101836 (rank : 60)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	106	Target Neighborhood Hits	364	Shared Neighborhood Hits	59
SwissProt Accessions	O00187, O75754, Q5TEQ5, Q5TER0, Q96QG4, Q9BZH0, Q9H498, Q9H499, Q9UBP3, Q9ULC7, Q9UMV3, Q9Y270	Gene names	MASP2
Domain Architecture
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

CSPG3_MOUSE
NC score	0.098295 (rank : 61)	θ value	θ > 10 (rank : 122)
Query Neighborhood Hits	106	Target Neighborhood Hits	657	Shared Neighborhood Hits	67
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

CS1B_MOUSE
NC score	0.095836 (rank : 62)	θ value	1.38821 (rank : 72)
Query Neighborhood Hits	106	Target Neighborhood Hits	361	Shared Neighborhood Hits	58
SwissProt Accessions	Q8CFG8	Gene names	C1sb, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-B subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-B subcomponent heavy chain; Complement C1s-B subcomponent light chain].

PERT_MOUSE
NC score	0.095373 (rank : 63)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	106	Target Neighborhood Hits	221	Shared Neighborhood Hits	57
SwissProt Accessions	P35419, Q8C8B1	Gene names	Tpo
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

CS1A_MOUSE
NC score	0.094178 (rank : 64)	θ value	1.38821 (rank : 71)
Query Neighborhood Hits	106	Target Neighborhood Hits	360	Shared Neighborhood Hits	58
SwissProt Accessions	Q8CG14, Q8BJC4, Q8CH28, Q8VBY4	Gene names	C1sa, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-A subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-A subcomponent heavy chain; Complement C1s-A subcomponent light chain].

CSPG3_HUMAN
NC score	0.093354 (rank : 65)	θ value	θ > 10 (rank : 121)
Query Neighborhood Hits	106	Target Neighborhood Hits	676	Shared Neighborhood Hits	68
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

MASP1_HUMAN
NC score	0.092255 (rank : 66)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	106	Target Neighborhood Hits	369	Shared Neighborhood Hits	60
SwissProt Accessions	P48740, O95570, Q9UF09	Gene names	MASP1, CRARF, CRARF1, PRSS5
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) (Mannose-binding protein- associated serine protease) (MASP-1) [Contains: Complement-activating component of Ra-reactive factor heavy chain; Complement-activating component of Ra-reactive factor light chain].

KR107_HUMAN
NC score	0.088714 (rank : 67)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	106	Target Neighborhood Hits	330	Shared Neighborhood Hits	33
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

KR104_HUMAN
NC score	0.087772 (rank : 68)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	106	Target Neighborhood Hits	313	Shared Neighborhood Hits	32
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

NOTC1_MOUSE
NC score	0.087771 (rank : 69)	θ value	0.0563607 (rank : 43)
Query Neighborhood Hits	106	Target Neighborhood Hits	916	Shared Neighborhood Hits	58
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

PGCB_HUMAN
NC score	0.087502 (rank : 70)	θ value	1.06291 (rank : 68)
Query Neighborhood Hits	106	Target Neighborhood Hits	478	Shared Neighborhood Hits	57
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

SUSD3_HUMAN
NC score	0.087451 (rank : 71)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	106	Target Neighborhood Hits	32	Shared Neighborhood Hits	22
SwissProt Accessions	Q96L08, Q49AA6, Q6UXV7	Gene names	SUSD3, UNQ9387/PRO34275
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 3.

MEGF6_HUMAN
NC score	0.086334 (rank : 72)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	106	Target Neighborhood Hits	671	Shared Neighborhood Hits	53
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

PERT_HUMAN
NC score	0.085880 (rank : 73)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	106	Target Neighborhood Hits	221	Shared Neighborhood Hits	56
SwissProt Accessions	P07202, P09934, P09935, Q8IUL0, Q8NF94, Q8NF95, Q8NF96, Q8NF97, Q8TCI9	Gene names	TPO
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

NOTC3_MOUSE
NC score	0.085692 (rank : 74)	θ value	0.0736092 (rank : 48)
Query Neighborhood Hits	106	Target Neighborhood Hits	975	Shared Neighborhood Hits	55
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

CUBN_HUMAN
NC score	0.085595 (rank : 75)	θ value	θ > 10 (rank : 123)
Query Neighborhood Hits	106	Target Neighborhood Hits	482	Shared Neighborhood Hits	47
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

MASP1_MOUSE
NC score	0.085035 (rank : 76)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	106	Target Neighborhood Hits	364	Shared Neighborhood Hits	59
SwissProt Accessions	P98064	Gene names	Masp1, Crarf
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) [Contains: Complement- activating component of Ra-reactive factor heavy chain; Complement- activating component of Ra-reactive factor light chain].

NOTC3_HUMAN
NC score	0.084779 (rank : 77)	θ value	0.0736092 (rank : 47)
Query Neighborhood Hits	106	Target Neighborhood Hits	1062	Shared Neighborhood Hits	58
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

TNR14_HUMAN
NC score	0.083923 (rank : 78)	θ value	0.0431538 (rank : 41)
Query Neighborhood Hits	106	Target Neighborhood Hits	149	Shared Neighborhood Hits	22
SwissProt Accessions	Q92956, Q8WXR1, Q96J31, Q9UM65	Gene names	TNFRSF14, HVEA, HVEM
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 14 precursor (Herpesvirus entry mediator A) (Tumor necrosis factor receptor-like 2) (TR2).

NOTC1_HUMAN
NC score	0.083642 (rank : 79)	θ value	0.0736092 (rank : 46)
Query Neighborhood Hits	106	Target Neighborhood Hits	906	Shared Neighborhood Hits	60
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

SREC2_MOUSE
NC score	0.082829 (rank : 80)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	106	Target Neighborhood Hits	605	Shared Neighborhood Hits	38
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

CSPG2_HUMAN
NC score	0.082258 (rank : 81)	θ value	θ > 10 (rank : 119)
Query Neighborhood Hits	106	Target Neighborhood Hits	681	Shared Neighborhood Hits	60
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

CSPG2_MOUSE
NC score	0.082239 (rank : 82)	θ value	θ > 10 (rank : 120)
Query Neighborhood Hits	106	Target Neighborhood Hits	711	Shared Neighborhood Hits	60
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

NOTC2_HUMAN
NC score	0.081247 (rank : 83)	θ value	0.0961366 (rank : 53)
Query Neighborhood Hits	106	Target Neighborhood Hits	1113	Shared Neighborhood Hits	58
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC4_HUMAN
NC score	0.080892 (rank : 84)	θ value	0.00228821 (rank : 36)
Query Neighborhood Hits	106	Target Neighborhood Hits	905	Shared Neighborhood Hits	55
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

ZAN_MOUSE
NC score	0.080228 (rank : 85)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	106	Target Neighborhood Hits	808	Shared Neighborhood Hits	53
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

NOTC2_MOUSE
NC score	0.080203 (rank : 86)	θ value	0.0431538 (rank : 40)
Query Neighborhood Hits	106	Target Neighborhood Hits	1069	Shared Neighborhood Hits	55
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

PGCB_MOUSE
NC score	0.079946 (rank : 87)	θ value	1.38821 (rank : 74)
Query Neighborhood Hits	106	Target Neighborhood Hits	459	Shared Neighborhood Hits	57
SwissProt Accessions	Q61361	Gene names	Bcan
Domain Architecture
Description	Brevican core protein precursor.

CUBN_MOUSE
NC score	0.079817 (rank : 88)	θ value	θ > 10 (rank : 124)
Query Neighborhood Hits	106	Target Neighborhood Hits	477	Shared Neighborhood Hits	46
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

C1R_HUMAN
NC score	0.078958 (rank : 89)	θ value	0.163984 (rank : 57)
Query Neighborhood Hits	106	Target Neighborhood Hits	364	Shared Neighborhood Hits	56
SwissProt Accessions	P00736, Q8J012	Gene names	C1R
Domain Architecture
Description	Complement C1r subcomponent precursor (EC 3.4.21.41) (Complement component 1, r subcomponent) [Contains: Complement C1r subcomponent heavy chain; Complement C1r subcomponent light chain].

NOTC4_MOUSE
NC score	0.078017 (rank : 90)	θ value	0.0330416 (rank : 39)
Query Neighborhood Hits	106	Target Neighborhood Hits	872	Shared Neighborhood Hits	55
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

KR102_HUMAN
NC score	0.077774 (rank : 91)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	106	Target Neighborhood Hits	264	Shared Neighborhood Hits	31
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

PCSK5_MOUSE
NC score	0.075479 (rank : 92)	θ value	0.0736092 (rank : 49)
Query Neighborhood Hits	106	Target Neighborhood Hits	613	Shared Neighborhood Hits	43
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

C1RB_MOUSE
NC score	0.074693 (rank : 93)	θ value	θ > 10 (rank : 113)
Query Neighborhood Hits	106	Target Neighborhood Hits	380	Shared Neighborhood Hits	53
SwissProt Accessions	Q8CFG9	Gene names	C1rb, C1r
Domain Architecture	No domain graphic available
Description	Complement C1r-B subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-B subcomponent) [Contains: Complement C1r-B subcomponent heavy chain; Complement C1r-B subcomponent light chain].

C1RA_MOUSE
NC score	0.074678 (rank : 94)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	106	Target Neighborhood Hits	379	Shared Neighborhood Hits	53
SwissProt Accessions	Q8CG16, Q99KI6, Q9ET60	Gene names	C1ra, C1r
Domain Architecture
Description	Complement C1r-A subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-A subcomponent) [Contains: Complement C1r-A subcomponent heavy chain; Complement C1r-A subcomponent light chain].

KR106_HUMAN
NC score	0.074028 (rank : 95)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	106	Target Neighborhood Hits	347	Shared Neighborhood Hits	36
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

PGCA_HUMAN
NC score	0.072967 (rank : 96)	θ value	5.27518 (rank : 89)
Query Neighborhood Hits	106	Target Neighborhood Hits	821	Shared Neighborhood Hits	59
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

KR101_HUMAN
NC score	0.072800 (rank : 97)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	106	Target Neighborhood Hits	261	Shared Neighborhood Hits	31
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

JAG1_HUMAN
NC score	0.072386 (rank : 98)	θ value	1.06291 (rank : 66)
Query Neighborhood Hits	106	Target Neighborhood Hits	514	Shared Neighborhood Hits	51
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

KR10B_HUMAN
NC score	0.072129 (rank : 99)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	106	Target Neighborhood Hits	269	Shared Neighborhood Hits	26
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

LTBP2_MOUSE
NC score	0.072053 (rank : 100)	θ value	1.06291 (rank : 67)
Query Neighborhood Hits	106	Target Neighborhood Hits	617	Shared Neighborhood Hits	52
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

KR109_HUMAN
NC score	0.071850 (rank : 101)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	106	Target Neighborhood Hits	226	Shared Neighborhood Hits	27
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

JAG1_MOUSE
NC score	0.071647 (rank : 102)	θ value	6.88961 (rank : 100)
Query Neighborhood Hits	106	Target Neighborhood Hits	518	Shared Neighborhood Hits	50
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

LTBP4_MOUSE
NC score	0.068738 (rank : 103)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	106	Target Neighborhood Hits	607	Shared Neighborhood Hits	47
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

PGCA_MOUSE
NC score	0.068369 (rank : 104)	θ value	3.0926 (rank : 81)
Query Neighborhood Hits	106	Target Neighborhood Hits	643	Shared Neighborhood Hits	42
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

LTBP2_HUMAN
NC score	0.066739 (rank : 105)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	106	Target Neighborhood Hits	552	Shared Neighborhood Hits	56
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

SREC2_HUMAN
NC score	0.065954 (rank : 106)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	106	Target Neighborhood Hits	645	Shared Neighborhood Hits	39
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

FBN1_MOUSE
NC score	0.065547 (rank : 107)	θ value	6.88961 (rank : 96)
Query Neighborhood Hits	106	Target Neighborhood Hits	563	Shared Neighborhood Hits	50
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

FBN1_HUMAN
NC score	0.065292 (rank : 108)	θ value	θ > 10 (rank : 141)
Query Neighborhood Hits	106	Target Neighborhood Hits	557	Shared Neighborhood Hits	49
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

FBN2_MOUSE
NC score	0.064298 (rank : 109)	θ value	θ > 10 (rank : 143)
Query Neighborhood Hits	106	Target Neighborhood Hits	549	Shared Neighborhood Hits	53
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

IL2RA_HUMAN
NC score	0.064146 (rank : 110)	θ value	θ > 10 (rank : 147)
Query Neighborhood Hits	106	Target Neighborhood Hits	32	Shared Neighborhood Hits	19
SwissProt Accessions	P01589	Gene names	IL2RA
Domain Architecture
Description	Interleukin-2 receptor alpha chain precursor (IL-2 receptor alpha subunit) (IL-2-RA) (IL2-RA) (p55) (TAC antigen) (CD25 antigen).

KR108_HUMAN
NC score	0.064121 (rank : 111)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	106	Target Neighborhood Hits	226	Shared Neighborhood Hits	30
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

SREC_HUMAN
NC score	0.063494 (rank : 112)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	106	Target Neighborhood Hits	645	Shared Neighborhood Hits	39
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

JAG2_MOUSE
NC score	0.061699 (rank : 113)	θ value	θ > 10 (rank : 149)
Query Neighborhood Hits	106	Target Neighborhood Hits	504	Shared Neighborhood Hits	49
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

FBN2_HUMAN
NC score	0.061554 (rank : 114)	θ value	θ > 10 (rank : 142)
Query Neighborhood Hits	106	Target Neighborhood Hits	560	Shared Neighborhood Hits	49
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

JAG2_HUMAN
NC score	0.060647 (rank : 115)	θ value	θ > 10 (rank : 148)
Query Neighborhood Hits	106	Target Neighborhood Hits	491	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

FBN3_HUMAN
NC score	0.060443 (rank : 116)	θ value	θ > 10 (rank : 144)
Query Neighborhood Hits	106	Target Neighborhood Hits	543	Shared Neighborhood Hits	46
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

ATRN_HUMAN
NC score	0.060402 (rank : 117)	θ value	θ > 10 (rank : 107)
Query Neighborhood Hits	106	Target Neighborhood Hits	525	Shared Neighborhood Hits	39
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

TLL1_MOUSE
NC score	0.059691 (rank : 118)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	106	Target Neighborhood Hits	237	Shared Neighborhood Hits	30
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

LTBP3_MOUSE
NC score	0.059488 (rank : 119)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	106	Target Neighborhood Hits	475	Shared Neighborhood Hits	54
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

DLL1_MOUSE
NC score	0.058961 (rank : 120)	θ value	θ > 10 (rank : 128)
Query Neighborhood Hits	106	Target Neighborhood Hits	456	Shared Neighborhood Hits	44
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

DLL1_HUMAN
NC score	0.058905 (rank : 121)	θ value	θ > 10 (rank : 127)
Query Neighborhood Hits	106	Target Neighborhood Hits	455	Shared Neighborhood Hits	40
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

TNR8_MOUSE
NC score	0.058785 (rank : 122)	θ value	0.0736092 (rank : 51)
Query Neighborhood Hits	106	Target Neighborhood Hits	208	Shared Neighborhood Hits	16
SwissProt Accessions	Q60846	Gene names	Tnfrsf8
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 8 precursor (CD30L receptor) (Lymphocyte activation antigen CD30).

TLL2_MOUSE
NC score	0.058641 (rank : 123)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	106	Target Neighborhood Hits	240	Shared Neighborhood Hits	32
SwissProt Accessions	Q9WVM6	Gene names	Tll2
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

ATRN_MOUSE
NC score	0.058327 (rank : 124)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	106	Target Neighborhood Hits	519	Shared Neighborhood Hits	41
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

DNER_HUMAN
NC score	0.058312 (rank : 125)	θ value	θ > 10 (rank : 133)
Query Neighborhood Hits	106	Target Neighborhood Hits	460	Shared Neighborhood Hits	43
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

BMP1_MOUSE
NC score	0.057709 (rank : 126)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	106	Target Neighborhood Hits	236	Shared Neighborhood Hits	30
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

FBLN1_MOUSE
NC score	0.057580 (rank : 127)	θ value	θ > 10 (rank : 138)
Query Neighborhood Hits	106	Target Neighborhood Hits	329	Shared Neighborhood Hits	39
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

TLL2_HUMAN
NC score	0.057522 (rank : 128)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	106	Target Neighborhood Hits	241	Shared Neighborhood Hits	28
SwissProt Accessions	Q9Y6L7, Q6PJN5, Q9UQ00	Gene names	TLL2, KIAA0932
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

LTBP3_HUMAN
NC score	0.057512 (rank : 129)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	106	Target Neighborhood Hits	502	Shared Neighborhood Hits	52
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

BMP1_HUMAN
NC score	0.057467 (rank : 130)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	106	Target Neighborhood Hits	233	Shared Neighborhood Hits	30
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

DNER_MOUSE
NC score	0.057459 (rank : 131)	θ value	θ > 10 (rank : 134)
Query Neighborhood Hits	106	Target Neighborhood Hits	413	Shared Neighborhood Hits	42
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

FBLN2_MOUSE
NC score	0.057350 (rank : 132)	θ value	θ > 10 (rank : 140)
Query Neighborhood Hits	106	Target Neighborhood Hits	505	Shared Neighborhood Hits	45
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

TLL1_HUMAN
NC score	0.057298 (rank : 133)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	106	Target Neighborhood Hits	236	Shared Neighborhood Hits	29
SwissProt Accessions	O43897, Q96AN3, Q9NQS4	Gene names	TLL1, TLL
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-).

CRUM1_HUMAN
NC score	0.057237 (rank : 134)	θ value	θ > 10 (rank : 116)
Query Neighborhood Hits	106	Target Neighborhood Hits	457	Shared Neighborhood Hits	44
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

STAB2_MOUSE
NC score	0.056654 (rank : 135)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	106	Target Neighborhood Hits	528	Shared Neighborhood Hits	47
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

C1QR1_MOUSE
NC score	0.056270 (rank : 136)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	106	Target Neighborhood Hits	342	Shared Neighborhood Hits	38
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

KR10C_HUMAN
NC score	0.056102 (rank : 137)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	106	Target Neighborhood Hits	219	Shared Neighborhood Hits	25
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

CRUM2_HUMAN
NC score	0.055843 (rank : 138)	θ value	θ > 10 (rank : 118)
Query Neighborhood Hits	106	Target Neighborhood Hits	453	Shared Neighborhood Hits	43
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

SCUB3_HUMAN
NC score	0.055653 (rank : 139)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	106	Target Neighborhood Hits	428	Shared Neighborhood Hits	43
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

STAB1_MOUSE
NC score	0.055622 (rank : 140)	θ value	5.27518 (rank : 91)
Query Neighborhood Hits	106	Target Neighborhood Hits	566	Shared Neighborhood Hits	48
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

FBLN2_HUMAN
NC score	0.055476 (rank : 141)	θ value	θ > 10 (rank : 139)
Query Neighborhood Hits	106	Target Neighborhood Hits	392	Shared Neighborhood Hits	40
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

SSPO_MOUSE
NC score	0.055235 (rank : 142)	θ value	0.0736092 (rank : 50)
Query Neighborhood Hits	106	Target Neighborhood Hits	800	Shared Neighborhood Hits	46
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

CRUM1_MOUSE
NC score	0.055015 (rank : 143)	θ value	θ > 10 (rank : 117)
Query Neighborhood Hits	106	Target Neighborhood Hits	444	Shared Neighborhood Hits	43
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

DLL4_MOUSE
NC score	0.054444 (rank : 144)	θ value	θ > 10 (rank : 132)
Query Neighborhood Hits	106	Target Neighborhood Hits	440	Shared Neighborhood Hits	42
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

SCUB3_MOUSE
NC score	0.054356 (rank : 145)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	106	Target Neighborhood Hits	442	Shared Neighborhood Hits	44
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

LTB1L_HUMAN
NC score	0.054079 (rank : 146)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	106	Target Neighborhood Hits	553	Shared Neighborhood Hits	49
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
NC score	0.053904 (rank : 147)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	106	Target Neighborhood Hits	502	Shared Neighborhood Hits	48
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

EGFL9_HUMAN
NC score	0.053367 (rank : 148)	θ value	θ > 10 (rank : 135)
Query Neighborhood Hits	106	Target Neighborhood Hits	365	Shared Neighborhood Hits	38
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

DLK_HUMAN
NC score	0.053305 (rank : 149)	θ value	θ > 10 (rank : 125)
Query Neighborhood Hits	106	Target Neighborhood Hits	401	Shared Neighborhood Hits	45
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

EGFL9_MOUSE
NC score	0.053014 (rank : 150)	θ value	θ > 10 (rank : 136)
Query Neighborhood Hits	106	Target Neighborhood Hits	379	Shared Neighborhood Hits	37
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

DLK_MOUSE
NC score	0.052973 (rank : 151)	θ value	θ > 10 (rank : 126)
Query Neighborhood Hits	106	Target Neighborhood Hits	374	Shared Neighborhood Hits	39
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

FRAS1_MOUSE
NC score	0.052949 (rank : 152)	θ value	8.99809 (rank : 103)
Query Neighborhood Hits	106	Target Neighborhood Hits	747	Shared Neighborhood Hits	41
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

DLL3_MOUSE
NC score	0.052779 (rank : 153)	θ value	θ > 10 (rank : 130)
Query Neighborhood Hits	106	Target Neighborhood Hits	399	Shared Neighborhood Hits	40
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

DLL3_HUMAN
NC score	0.052454 (rank : 154)	θ value	θ > 10 (rank : 129)
Query Neighborhood Hits	106	Target Neighborhood Hits	419	Shared Neighborhood Hits	39
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

FBLN1_HUMAN
NC score	0.052234 (rank : 155)	θ value	θ > 10 (rank : 137)
Query Neighborhood Hits	106	Target Neighborhood Hits	324	Shared Neighborhood Hits	39
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

LAMA5_HUMAN
NC score	0.052232 (rank : 156)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	106	Target Neighborhood Hits	976	Shared Neighborhood Hits	44
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

FRAS1_HUMAN
NC score	0.051916 (rank : 157)	θ value	6.88961 (rank : 97)
Query Neighborhood Hits	106	Target Neighborhood Hits	759	Shared Neighborhood Hits	42
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

LAMC3_HUMAN
NC score	0.051823 (rank : 158)	θ value	0.47712 (rank : 63)
Query Neighborhood Hits	106	Target Neighborhood Hits	588	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

DLL4_HUMAN
NC score	0.051665 (rank : 159)	θ value	θ > 10 (rank : 131)
Query Neighborhood Hits	106	Target Neighborhood Hits	435	Shared Neighborhood Hits	40
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

NELL2_MOUSE
NC score	0.051543 (rank : 160)	θ value	3.0926 (rank : 80)
Query Neighborhood Hits	106	Target Neighborhood Hits	436	Shared Neighborhood Hits	43
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

PCSK5_HUMAN
NC score	0.050669 (rank : 161)	θ value	0.125558 (rank : 55)
Query Neighborhood Hits	106	Target Neighborhood Hits	291	Shared Neighborhood Hits	33
SwissProt Accessions	Q92824, Q13527	Gene names	PCSK5, PC5, PC6
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (hPC6).

LAMA5_MOUSE
NC score	0.045538 (rank : 162)	θ value	1.38821 (rank : 73)
Query Neighborhood Hits	106	Target Neighborhood Hits	828	Shared Neighborhood Hits	41
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

ADA17_HUMAN
NC score	0.041074 (rank : 163)	θ value	0.365318 (rank : 60)
Query Neighborhood Hits	106	Target Neighborhood Hits	223	Shared Neighborhood Hits	26
SwissProt Accessions	P78536, O60226	Gene names	ADAM17, CSVP, TACE
Domain Architecture
Description	ADAM 17 precursor (EC 3.4.24.86) (A disintegrin and metalloproteinase domain 17) (TNF-alpha-converting enzyme) (TNF-alpha convertase) (Snake venom-like protease) (CD156b antigen).

APR3_MOUSE
NC score	0.040036 (rank : 164)	θ value	4.03905 (rank : 83)
Query Neighborhood Hits	106	Target Neighborhood Hits	61	Shared Neighborhood Hits	13
SwissProt Accessions	Q6PGD0, Q3UAH4, Q810Q3, Q9DD14	Gene names	Apr3
Domain Architecture	No domain graphic available
Description	Apoptosis-related protein 3 precursor (APR-3).

USH2A_HUMAN
NC score	0.039285 (rank : 165)	θ value	1.38821 (rank : 75)
Query Neighborhood Hits	106	Target Neighborhood Hits	600	Shared Neighborhood Hits	34
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

ADA10_MOUSE
NC score	0.037239 (rank : 166)	θ value	0.813845 (rank : 65)
Query Neighborhood Hits	106	Target Neighborhood Hits	194	Shared Neighborhood Hits	18
SwissProt Accessions	O35598	Gene names	Adam10, Kuz, Madm
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog).

ADAM8_HUMAN
NC score	0.033103 (rank : 167)	θ value	0.62314 (rank : 64)
Query Neighborhood Hits	106	Target Neighborhood Hits	327	Shared Neighborhood Hits	31
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

ADAM7_MOUSE
NC score	0.032987 (rank : 168)	θ value	0.0330416 (rank : 38)
Query Neighborhood Hits	106	Target Neighborhood Hits	200	Shared Neighborhood Hits	24
SwissProt Accessions	O35227	Gene names	Adam7
Domain Architecture
Description	ADAM 7 precursor (A disintegrin and metalloproteinase domain 7).

ADA10_HUMAN
NC score	0.032665 (rank : 169)	θ value	8.99809 (rank : 101)
Query Neighborhood Hits	106	Target Neighborhood Hits	189	Shared Neighborhood Hits	18
SwissProt Accessions	O14672, Q10742, Q92650	Gene names	ADAM10, KUZ, MADM
Domain Architecture
Description	ADAM 10 precursor (EC 3.4.24.81) (A disintegrin and metalloproteinase domain 10) (Mammalian disintegrin-metalloprotease) (Kuzbanian protein homolog) (CDw156c antigen).

COLQ_HUMAN
NC score	0.032592 (rank : 170)	θ value	2.36792 (rank : 78)
Query Neighborhood Hits	106	Target Neighborhood Hits	193	Shared Neighborhood Hits	8
SwissProt Accessions	Q9Y215, Q6DK18, Q6YH18, Q6YH19, Q6YH20, Q6YH21, Q9NP18, Q9NP19, Q9NP20, Q9NP21, Q9NP22, Q9NP23, Q9NP24, Q9UP88	Gene names	COLQ
Domain Architecture	No domain graphic available
Description	Acetylcholinesterase collagenic tail peptide precursor (AChE Q subunit) (Acetylcholinesterase-associated collagen).

ITB6_MOUSE
NC score	0.030997 (rank : 171)	θ value	6.88961 (rank : 99)
Query Neighborhood Hits	106	Target Neighborhood Hits	341	Shared Neighborhood Hits	30
SwissProt Accessions	Q9Z0T9	Gene names	Itgb6
Domain Architecture
Description	Integrin beta-6 precursor.

ADM1A_MOUSE
NC score	0.030983 (rank : 172)	θ value	0.279714 (rank : 59)
Query Neighborhood Hits	106	Target Neighborhood Hits	230	Shared Neighborhood Hits	29
SwissProt Accessions	Q60813, Q60617, Q80WR7, Q8R533	Gene names	Adam1a, Adam1, Ftna
Domain Architecture
Description	ADAM 1a precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 1a) (Fertilin alpha 1a subunit).

TNAP3_MOUSE
NC score	0.028335 (rank : 173)	θ value	1.06291 (rank : 69)
Query Neighborhood Hits	106	Target Neighborhood Hits	35	Shared Neighborhood Hits	6
SwissProt Accessions	Q60769	Gene names	Tnfaip3, Tnfip3
Domain Architecture
Description	Tumor necrosis factor, alpha-induced protein 3 (EC 3.-.-.-) (Putative DNA-binding protein A20) (Zinc finger protein A20).

ADA25_MOUSE
NC score	0.027184 (rank : 174)	θ value	3.0926 (rank : 79)
Query Neighborhood Hits	106	Target Neighborhood Hits	213	Shared Neighborhood Hits	23
SwissProt Accessions	Q9R159, Q9D4E4	Gene names	Adam25
Domain Architecture
Description	ADAM 25 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 25) (Testase 2).

FAAA_MOUSE
NC score	0.026272 (rank : 175)	θ value	1.81305 (rank : 76)
Query Neighborhood Hits	106	Target Neighborhood Hits	8	Shared Neighborhood Hits	2
SwissProt Accessions	P35505	Gene names	Fah
Domain Architecture
Description	Fumarylacetoacetase (EC 3.7.1.2) (Fumarylacetoacetate hydrolase) (Beta-diketonase) (FAA).

ATS7_HUMAN
NC score	0.019955 (rank : 176)	θ value	0.365318 (rank : 61)
Query Neighborhood Hits	106	Target Neighborhood Hits	169	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UKP4	Gene names	ADAMTS7
Domain Architecture
Description	ADAMTS-7 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 7) (ADAM-TS 7) (ADAM-TS7).

TNAP3_HUMAN
NC score	0.019710 (rank : 177)	θ value	8.99809 (rank : 105)
Query Neighborhood Hits	106	Target Neighborhood Hits	58	Shared Neighborhood Hits	5
SwissProt Accessions	P21580, Q5VXQ7, Q9NSR6	Gene names	TNFAIP3
Domain Architecture
Description	Tumor necrosis factor, alpha-induced protein 3 (EC 3.-.-.-) (Putative DNA-binding protein A20) (Zinc finger protein A20).

T2EA_HUMAN
NC score	0.019080 (rank : 178)	θ value	4.03905 (rank : 87)
Query Neighborhood Hits	106	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	P29083, Q16103	Gene names	GTF2E1, TF2E1
Domain Architecture
Description	Transcription initiation factor IIE subunit alpha (TFIIE-alpha) (General transcription factor IIE 56 kDa subunit).

CO8A_HUMAN
NC score	0.015467 (rank : 179)	θ value	6.88961 (rank : 94)
Query Neighborhood Hits	106	Target Neighborhood Hits	200	Shared Neighborhood Hits	17
SwissProt Accessions	P07357, Q13668, Q9H130	Gene names	C8A
Domain Architecture
Description	Complement component C8 alpha chain precursor (Complement component 8 subunit alpha).

BAT2_MOUSE
NC score	0.011406 (rank : 180)	θ value	4.03905 (rank : 84)
Query Neighborhood Hits	106	Target Neighborhood Hits	947	Shared Neighborhood Hits	11
SwissProt Accessions	Q7TSC1, Q923A9, Q9Z1R1	Gene names	Bat2
Domain Architecture	No domain graphic available
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

MYT1_HUMAN
NC score	0.008754 (rank : 181)	θ value	4.03905 (rank : 86)
Query Neighborhood Hits	106	Target Neighborhood Hits	475	Shared Neighborhood Hits	3
SwissProt Accessions	Q01538, O94922, Q9UPV2	Gene names	MYT1, KIAA0835, KIAA1050, MTF1, MYTI, PLPB1
Domain Architecture
Description	Myelin transcription factor 1 (MyT1) (MyTI) (Proteolipid protein- binding protein) (PLPB1).

HXA5_MOUSE
NC score	0.006494 (rank : 182)	θ value	1.81305 (rank : 77)
Query Neighborhood Hits	106	Target Neighborhood Hits	338	Shared Neighborhood Hits	4
SwissProt Accessions	P09021, Q91VQ5	Gene names	Hoxa5, Hox-1.3, Hoxa-5
Domain Architecture
Description	Homeobox protein Hox-A5 (Hox-1.3) (M2).

HXA5_HUMAN
NC score	0.005175 (rank : 183)	θ value	4.03905 (rank : 85)
Query Neighborhood Hits	106	Target Neighborhood Hits	336	Shared Neighborhood Hits	4
SwissProt Accessions	P20719, O43367, Q96CY6	Gene names	HOXA5, HOX1C
Domain Architecture
Description	Homeobox protein Hox-A5 (Hox-1C).

COIA1_MOUSE
NC score	0.004958 (rank : 184)	θ value	6.88961 (rank : 95)
Query Neighborhood Hits	106	Target Neighborhood Hits	481	Shared Neighborhood Hits	10
SwissProt Accessions	P39061, Q60672, Q61437, Q62001, Q62002, Q9JK63	Gene names	Col18a1
Domain Architecture
Description	Collagen alpha-1(XVIII) chain precursor [Contains: Endostatin].

GALT6_MOUSE
NC score	0.003157 (rank : 185)	θ value	6.88961 (rank : 98)
Query Neighborhood Hits	106	Target Neighborhood Hits	57	Shared Neighborhood Hits	2
SwissProt Accessions	Q8C7U7, Q3TWF0, Q8CED2, Q9QZ16	Gene names	Galnt6
Domain Architecture	No domain graphic available
Description	Polypeptide N-acetylgalactosaminyltransferase 6 (EC 2.4.1.41) (Protein-UDP acetylgalactosaminyltransferase 6) (UDP- GalNAc:polypeptide N-acetylgalactosaminyltransferase 6) (Polypeptide GalNAc transferase 6) (GalNAc-T6) (pp-GaNTase 6).

TITIN_HUMAN
NC score	-0.002290 (rank : 186)	θ value	5.27518 (rank : 92)
Query Neighborhood Hits	106	Target Neighborhood Hits	2923	Shared Neighborhood Hits	17
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

ZN444_HUMAN
NC score	-0.002752 (rank : 187)	θ value	8.99809 (rank : 106)
Query Neighborhood Hits	106	Target Neighborhood Hits	701	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N0Y2, Q8TEQ9, Q8WU35, Q9NUU1	Gene names	ZNF444, EZF2, ZSCAN17
Domain Architecture
Description	Zinc finger protein 444 (Endothelial zinc finger protein 2) (EZF-2) (Zinc finger and SCAN domain-containing protein 17).

ZN548_HUMAN
NC score	-0.002822 (rank : 188)	θ value	3.0926 (rank : 82)
Query Neighborhood Hits	106	Target Neighborhood Hits	739	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NEK5, Q96M05	Gene names	ZNF548
Domain Architecture	No domain graphic available
Description	Zinc finger protein 548.