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Network neighborhood for query Sequence : T2EA_HUMAN

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T2EA_HUMAN
SwissProt Accessions	P29083, Q16103	Gene names	GTF2E1, TF2E1
Domain Architecture
Description	Transcription initiation factor IIE subunit alpha (TFIIE-alpha) (General transcription factor IIE 56 kDa subunit).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

T2EA_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	19	Target Neighborhood Hits	19	Shared Neighborhood Hits	19
SwissProt Accessions	P29083, Q16103	Gene names	GTF2E1, TF2E1
Domain Architecture
Description	Transcription initiation factor IIE subunit alpha (TFIIE-alpha) (General transcription factor IIE 56 kDa subunit).

T2EA_MOUSE
θ value	0 (rank : 2)	NC score	0.994206 (rank : 2)
Query Neighborhood Hits	19	Target Neighborhood Hits	18	Shared Neighborhood Hits	11
SwissProt Accessions	Q9D0D5, Q544T0	Gene names	Gtf2e1
Domain Architecture
Description	Transcription initiation factor IIE subunit alpha (TFIIE-alpha) (General transcription factor IIE 56 kDa subunit).

ZN700_HUMAN
θ value	0.0330416 (rank : 3)	NC score	0.011948 (rank : 17)
Query Neighborhood Hits	19	Target Neighborhood Hits	772	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H0M5	Gene names	ZNF700
Domain Architecture	No domain graphic available
Description	Zinc finger protein 700.

ROBO2_MOUSE
θ value	0.0961366 (rank : 4)	NC score	0.019143 (rank : 11)
Query Neighborhood Hits	19	Target Neighborhood Hits	504	Shared Neighborhood Hits	2
SwissProt Accessions	Q7TPD3, Q8BJ59	Gene names	Robo2, Kiaa1568
Domain Architecture
Description	Roundabout homolog 2 precursor.

DSG2_MOUSE
θ value	0.62314 (rank : 5)	NC score	0.013799 (rank : 16)
Query Neighborhood Hits	19	Target Neighborhood Hits	174	Shared Neighborhood Hits	2
SwissProt Accessions	O55111, Q8K069, Q8R517	Gene names	Dsg2
Domain Architecture
Description	Desmoglein-2 precursor.

ANLN_HUMAN
θ value	0.813845 (rank : 6)	NC score	0.051107 (rank : 3)
Query Neighborhood Hits	19	Target Neighborhood Hits	222	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NQW6, Q5CZ78, Q6NSK5, Q9H8Y4, Q9NVN9, Q9NVP0	Gene names	ANLN
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

GAS8_MOUSE
θ value	3.0926 (rank : 7)	NC score	0.017767 (rank : 13)
Query Neighborhood Hits	19	Target Neighborhood Hits	622	Shared Neighborhood Hits	3
SwissProt Accessions	Q60779, Q99L71	Gene names	Gas8, Gas11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

K0460_HUMAN
θ value	3.0926 (rank : 8)	NC score	0.038164 (rank : 4)
Query Neighborhood Hits	19	Target Neighborhood Hits	357	Shared Neighborhood Hits	4
SwissProt Accessions	Q5VT52, O75048, Q5VT53, Q6MZL4, Q86XD2	Gene names	KIAA0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

ZN440_HUMAN
θ value	3.0926 (rank : 9)	NC score	0.006692 (rank : 18)
Query Neighborhood Hits	19	Target Neighborhood Hits	750	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IYI8, Q8N1R9	Gene names	ZNF440
Domain Architecture
Description	Zinc finger protein 440.

LEO1_MOUSE
θ value	4.03905 (rank : 10)	NC score	0.020990 (rank : 9)
Query Neighborhood Hits	19	Target Neighborhood Hits	946	Shared Neighborhood Hits	7
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

PAP2_HUMAN
θ value	4.03905 (rank : 11)	NC score	0.019080 (rank : 12)
Query Neighborhood Hits	19	Target Neighborhood Hits	106	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BXP8, Q96PH7, Q96PH8, Q9H4C9	Gene names	PAPPA2
Domain Architecture	No domain graphic available
Description	Pappalysin-2 precursor (EC 3.4.24.-) (Pregnancy-associated plasma protein-A2) (PAPP-A2) (Pregnancy-associated plasma protein-E1) (PAPP- E).

PICAL_HUMAN
θ value	4.03905 (rank : 12)	NC score	0.032380 (rank : 5)
Query Neighborhood Hits	19	Target Neighborhood Hits	57	Shared Neighborhood Hits	3
SwissProt Accessions	Q13492, O60700, Q86XZ9	Gene names	PICALM, CALM
Domain Architecture
Description	Phosphatidylinositol-binding clathrin assembly protein (Clathrin assembly lymphoid myeloid leukemia protein).

PICA_MOUSE
θ value	4.03905 (rank : 13)	NC score	0.032332 (rank : 6)
Query Neighborhood Hits	19	Target Neighborhood Hits	63	Shared Neighborhood Hits	3
SwissProt Accessions	Q7M6Y3, Q3TS04, Q811P1, Q8BUF6, Q8CIH8, Q8R0A9, Q8R3E1, Q8VDN5, Q921L0	Gene names	Picalm, Calm, Fit1
Domain Architecture
Description	Phosphatidylinositol-binding clathrin assembly protein (Clathrin assembly lymphoid myeloid leukemia) (CALM).

XPC_MOUSE
θ value	4.03905 (rank : 14)	NC score	0.026265 (rank : 7)
Query Neighborhood Hits	19	Target Neighborhood Hits	75	Shared Neighborhood Hits	2
SwissProt Accessions	P51612, P54732, Q3TKI2, Q920M1, Q9DBW7	Gene names	Xpc
Domain Architecture
Description	DNA-repair protein complementing XP-C cells homolog (Xeroderma pigmentosum group C-complementing protein homolog) (p125).

CHD1_HUMAN
θ value	5.27518 (rank : 15)	NC score	0.021193 (rank : 8)
Query Neighborhood Hits	19	Target Neighborhood Hits	337	Shared Neighborhood Hits	7
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

CHD1_MOUSE
θ value	5.27518 (rank : 16)	NC score	0.020977 (rank : 10)
Query Neighborhood Hits	19	Target Neighborhood Hits	266	Shared Neighborhood Hits	6
SwissProt Accessions	P40201	Gene names	Chd1, Chd-1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

NALP5_MOUSE
θ value	5.27518 (rank : 17)	NC score	0.017265 (rank : 14)
Query Neighborhood Hits	19	Target Neighborhood Hits	560	Shared Neighborhood Hits	7
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

ZN611_HUMAN
θ value	5.27518 (rank : 18)	NC score	0.005193 (rank : 19)
Query Neighborhood Hits	19	Target Neighborhood Hits	769	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N823, Q69YG9	Gene names	ZNF611
Domain Architecture	No domain graphic available
Description	Zinc finger protein 611.

IWS1_MOUSE
θ value	8.99809 (rank : 19)	NC score	0.014615 (rank : 15)
Query Neighborhood Hits	19	Target Neighborhood Hits	1258	Shared Neighborhood Hits	8
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

Hits sorted by NC score

T2EA_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	19	Target Neighborhood Hits	19	Shared Neighborhood Hits	19
SwissProt Accessions	P29083, Q16103	Gene names	GTF2E1, TF2E1
Domain Architecture
Description	Transcription initiation factor IIE subunit alpha (TFIIE-alpha) (General transcription factor IIE 56 kDa subunit).

T2EA_MOUSE
NC score	0.994206 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	19	Target Neighborhood Hits	18	Shared Neighborhood Hits	11
SwissProt Accessions	Q9D0D5, Q544T0	Gene names	Gtf2e1
Domain Architecture
Description	Transcription initiation factor IIE subunit alpha (TFIIE-alpha) (General transcription factor IIE 56 kDa subunit).

ANLN_HUMAN
NC score	0.051107 (rank : 3)	θ value	0.813845 (rank : 6)
Query Neighborhood Hits	19	Target Neighborhood Hits	222	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NQW6, Q5CZ78, Q6NSK5, Q9H8Y4, Q9NVN9, Q9NVP0	Gene names	ANLN
Domain Architecture	No domain graphic available
Description	Actin-binding protein anillin.

K0460_HUMAN
NC score	0.038164 (rank : 4)	θ value	3.0926 (rank : 8)
Query Neighborhood Hits	19	Target Neighborhood Hits	357	Shared Neighborhood Hits	4
SwissProt Accessions	Q5VT52, O75048, Q5VT53, Q6MZL4, Q86XD2	Gene names	KIAA0460
Domain Architecture	No domain graphic available
Description	Protein KIAA0460.

PICAL_HUMAN
NC score	0.032380 (rank : 5)	θ value	4.03905 (rank : 12)
Query Neighborhood Hits	19	Target Neighborhood Hits	57	Shared Neighborhood Hits	3
SwissProt Accessions	Q13492, O60700, Q86XZ9	Gene names	PICALM, CALM
Domain Architecture
Description	Phosphatidylinositol-binding clathrin assembly protein (Clathrin assembly lymphoid myeloid leukemia protein).

PICA_MOUSE
NC score	0.032332 (rank : 6)	θ value	4.03905 (rank : 13)
Query Neighborhood Hits	19	Target Neighborhood Hits	63	Shared Neighborhood Hits	3
SwissProt Accessions	Q7M6Y3, Q3TS04, Q811P1, Q8BUF6, Q8CIH8, Q8R0A9, Q8R3E1, Q8VDN5, Q921L0	Gene names	Picalm, Calm, Fit1
Domain Architecture
Description	Phosphatidylinositol-binding clathrin assembly protein (Clathrin assembly lymphoid myeloid leukemia) (CALM).

XPC_MOUSE
NC score	0.026265 (rank : 7)	θ value	4.03905 (rank : 14)
Query Neighborhood Hits	19	Target Neighborhood Hits	75	Shared Neighborhood Hits	2
SwissProt Accessions	P51612, P54732, Q3TKI2, Q920M1, Q9DBW7	Gene names	Xpc
Domain Architecture
Description	DNA-repair protein complementing XP-C cells homolog (Xeroderma pigmentosum group C-complementing protein homolog) (p125).

CHD1_HUMAN
NC score	0.021193 (rank : 8)	θ value	5.27518 (rank : 15)
Query Neighborhood Hits	19	Target Neighborhood Hits	337	Shared Neighborhood Hits	7
SwissProt Accessions	O14646	Gene names	CHD1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

LEO1_MOUSE
NC score	0.020990 (rank : 9)	θ value	4.03905 (rank : 10)
Query Neighborhood Hits	19	Target Neighborhood Hits	946	Shared Neighborhood Hits	7
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

CHD1_MOUSE
NC score	0.020977 (rank : 10)	θ value	5.27518 (rank : 16)
Query Neighborhood Hits	19	Target Neighborhood Hits	266	Shared Neighborhood Hits	6
SwissProt Accessions	P40201	Gene names	Chd1, Chd-1
Domain Architecture
Description	Chromodomain-helicase-DNA-binding protein 1 (EC 3.6.1.-) (ATP- dependent helicase CHD1) (CHD-1).

ROBO2_MOUSE
NC score	0.019143 (rank : 11)	θ value	0.0961366 (rank : 4)
Query Neighborhood Hits	19	Target Neighborhood Hits	504	Shared Neighborhood Hits	2
SwissProt Accessions	Q7TPD3, Q8BJ59	Gene names	Robo2, Kiaa1568
Domain Architecture
Description	Roundabout homolog 2 precursor.

PAP2_HUMAN
NC score	0.019080 (rank : 12)	θ value	4.03905 (rank : 11)
Query Neighborhood Hits	19	Target Neighborhood Hits	106	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BXP8, Q96PH7, Q96PH8, Q9H4C9	Gene names	PAPPA2
Domain Architecture	No domain graphic available
Description	Pappalysin-2 precursor (EC 3.4.24.-) (Pregnancy-associated plasma protein-A2) (PAPP-A2) (Pregnancy-associated plasma protein-E1) (PAPP- E).

GAS8_MOUSE
NC score	0.017767 (rank : 13)	θ value	3.0926 (rank : 7)
Query Neighborhood Hits	19	Target Neighborhood Hits	622	Shared Neighborhood Hits	3
SwissProt Accessions	Q60779, Q99L71	Gene names	Gas8, Gas11
Domain Architecture	No domain graphic available
Description	Growth-arrest-specific protein 8 (Growth arrest-specific 11).

NALP5_MOUSE
NC score	0.017265 (rank : 14)	θ value	5.27518 (rank : 17)
Query Neighborhood Hits	19	Target Neighborhood Hits	560	Shared Neighborhood Hits	7
SwissProt Accessions	Q9R1M5, Q9JLR2	Gene names	Nalp5, Mater
Domain Architecture
Description	NACHT, LRR and PYD-containing protein 5 (Maternal antigen that embryos require) (Mater protein) (Ooplasm-specific protein 1) (OP1).

IWS1_MOUSE
NC score	0.014615 (rank : 15)	θ value	8.99809 (rank : 19)
Query Neighborhood Hits	19	Target Neighborhood Hits	1258	Shared Neighborhood Hits	8
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

DSG2_MOUSE
NC score	0.013799 (rank : 16)	θ value	0.62314 (rank : 5)
Query Neighborhood Hits	19	Target Neighborhood Hits	174	Shared Neighborhood Hits	2
SwissProt Accessions	O55111, Q8K069, Q8R517	Gene names	Dsg2
Domain Architecture
Description	Desmoglein-2 precursor.

ZN700_HUMAN
NC score	0.011948 (rank : 17)	θ value	0.0330416 (rank : 3)
Query Neighborhood Hits	19	Target Neighborhood Hits	772	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H0M5	Gene names	ZNF700
Domain Architecture	No domain graphic available
Description	Zinc finger protein 700.

ZN440_HUMAN
NC score	0.006692 (rank : 18)	θ value	3.0926 (rank : 9)
Query Neighborhood Hits	19	Target Neighborhood Hits	750	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IYI8, Q8N1R9	Gene names	ZNF440
Domain Architecture
Description	Zinc finger protein 440.

ZN611_HUMAN
NC score	0.005193 (rank : 19)	θ value	5.27518 (rank : 18)
Query Neighborhood Hits	19	Target Neighborhood Hits	769	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N823, Q69YG9	Gene names	ZNF611
Domain Architecture	No domain graphic available
Description	Zinc finger protein 611.