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Network neighborhood for query Sequence : MEP1A_HUMAN

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MEP1A_HUMAN
SwissProt Accessions	Q16819	Gene names	MEP1A
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit alpha) (PABA peptide hydrolase) (PPH alpha).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

MEP1A_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	162	Target Neighborhood Hits	162	Shared Neighborhood Hits	162
SwissProt Accessions	Q16819	Gene names	MEP1A
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit alpha) (PABA peptide hydrolase) (PPH alpha).

MEP1A_MOUSE
θ value	0 (rank : 2)	NC score	0.988926 (rank : 2)
Query Neighborhood Hits	162	Target Neighborhood Hits	166	Shared Neighborhood Hits	150
SwissProt Accessions	P28825	Gene names	Mep1a
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (MEP-1).

MEP1B_HUMAN
θ value	3.06949e-141 (rank : 3)	NC score	0.939359 (rank : 4)
Query Neighborhood Hits	162	Target Neighborhood Hits	98	Shared Neighborhood Hits	76
SwissProt Accessions	Q16820, Q670J1	Gene names	MEP1B
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta) (PABA peptide hydrolase) (PPH beta).

MEP1B_MOUSE
θ value	2.51683e-135 (rank : 4)	NC score	0.944689 (rank : 3)
Query Neighborhood Hits	162	Target Neighborhood Hits	127	Shared Neighborhood Hits	99
SwissProt Accessions	Q61847	Gene names	Mep1b, Mep-1b
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2).

ASTL_MOUSE
θ value	1.57365e-28 (rank : 5)	NC score	0.749189 (rank : 5)
Query Neighborhood Hits	162	Target Neighborhood Hits	20	Shared Neighborhood Hits	14
SwissProt Accessions	Q6HA09, Q8BMA1	Gene names	Astl
Domain Architecture	No domain graphic available
Description	Astacin-like metalloendopeptidase precursor (EC 3.4.-.-) (Oocyte astacin) (Ovastacin).

ASTL_HUMAN
θ value	1.33217e-27 (rank : 6)	NC score	0.705515 (rank : 6)
Query Neighborhood Hits	162	Target Neighborhood Hits	252	Shared Neighborhood Hits	18
SwissProt Accessions	Q6HA08	Gene names	ASTL
Domain Architecture	No domain graphic available
Description	Astacin-like metalloendopeptidase precursor (EC 3.4.-.-) (Oocyte astacin) (Ovastacin).

BMP1_HUMAN
θ value	1.29031e-22 (rank : 7)	NC score	0.465076 (rank : 9)
Query Neighborhood Hits	162	Target Neighborhood Hits	233	Shared Neighborhood Hits	89
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

BMP1_MOUSE
θ value	1.6852e-22 (rank : 8)	NC score	0.463992 (rank : 11)
Query Neighborhood Hits	162	Target Neighborhood Hits	236	Shared Neighborhood Hits	90
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

TLL1_MOUSE
θ value	2.20094e-22 (rank : 9)	NC score	0.465593 (rank : 8)
Query Neighborhood Hits	162	Target Neighborhood Hits	237	Shared Neighborhood Hits	91
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

TLL2_HUMAN
θ value	2.20094e-22 (rank : 10)	NC score	0.466946 (rank : 7)
Query Neighborhood Hits	162	Target Neighborhood Hits	241	Shared Neighborhood Hits	95
SwissProt Accessions	Q9Y6L7, Q6PJN5, Q9UQ00	Gene names	TLL2, KIAA0932
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

TLL2_MOUSE
θ value	2.20094e-22 (rank : 11)	NC score	0.462656 (rank : 12)
Query Neighborhood Hits	162	Target Neighborhood Hits	240	Shared Neighborhood Hits	89
SwissProt Accessions	Q9WVM6	Gene names	Tll2
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

TLL1_HUMAN
θ value	3.75424e-22 (rank : 12)	NC score	0.464024 (rank : 10)
Query Neighborhood Hits	162	Target Neighborhood Hits	236	Shared Neighborhood Hits	89
SwissProt Accessions	O43897, Q96AN3, Q9NQS4	Gene names	TLL1, TLL
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-).

MDGA1_HUMAN
θ value	5.62301e-10 (rank : 13)	NC score	0.200381 (rank : 71)
Query Neighborhood Hits	162	Target Neighborhood Hits	358	Shared Neighborhood Hits	17
SwissProt Accessions	Q8NFP4, Q8NBE3	Gene names	MDGA1, MAMDC3
Domain Architecture
Description	MAM domain-containing glycosylphosphatidylinositol anchor protein 1 precursor (MAM domain-containing protein 3) (GPI and MAM protein) (Glycosylphosphatidylinositol-MAM) (GPIM).

MAMC1_MOUSE
θ value	8.11959e-09 (rank : 14)	NC score	0.185751 (rank : 95)
Query Neighborhood Hits	162	Target Neighborhood Hits	357	Shared Neighborhood Hits	18
SwissProt Accessions	P60755	Gene names	Mamdc1, Mdga2
Domain Architecture
Description	MAM domain-containing protein 1 precursor (MAM domain-containing glycosylphosphatidylinositol anchor protein 2).

MAMC1_HUMAN
θ value	1.38499e-08 (rank : 15)	NC score	0.183785 (rank : 103)
Query Neighborhood Hits	162	Target Neighborhood Hits	357	Shared Neighborhood Hits	18
SwissProt Accessions	Q7Z553	Gene names	MAMDC1, MDGA2
Domain Architecture
Description	MAM domain-containing protein 1 precursor (MAM domain-containing glycosylphosphatidylinositol anchor protein 2).

ENTK_HUMAN
θ value	1.17247e-07 (rank : 16)	NC score	0.145723 (rank : 170)
Query Neighborhood Hits	162	Target Neighborhood Hits	310	Shared Neighborhood Hits	43
SwissProt Accessions	P98073	Gene names	PRSS7, ENTK
Domain Architecture
Description	Enteropeptidase precursor (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

MAMC2_MOUSE
θ value	1.29631e-06 (rank : 17)	NC score	0.327186 (rank : 13)
Query Neighborhood Hits	162	Target Neighborhood Hits	31	Shared Neighborhood Hits	16
SwissProt Accessions	Q8CG85, Q8BM24	Gene names	Mamdc2
Domain Architecture
Description	MAM domain-containing protein 2 precursor.

TRAF4_HUMAN
θ value	1.29631e-06 (rank : 18)	NC score	0.233543 (rank : 25)
Query Neighborhood Hits	162	Target Neighborhood Hits	373	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BUZ4, O75615, Q14848, Q2PJN8	Gene names	TRAF4, CART1, MLN62, RNF83
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich domain associated with RING and Traf domains protein 1) (Malignant 62) (RING finger protein 83).

TRAF4_MOUSE
θ value	2.21117e-06 (rank : 19)	NC score	0.238653 (rank : 23)
Query Neighborhood Hits	162	Target Neighborhood Hits	338	Shared Neighborhood Hits	14
SwissProt Accessions	Q61382	Gene names	Traf4, Cart1
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich motif associated to RING and Traf domains protein 1).

NOTC2_HUMAN
θ value	1.43324e-05 (rank : 20)	NC score	0.225369 (rank : 38)
Query Neighborhood Hits	162	Target Neighborhood Hits	1113	Shared Neighborhood Hits	138
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NRP1_MOUSE
θ value	1.87187e-05 (rank : 21)	NC score	0.279372 (rank : 17)
Query Neighborhood Hits	162	Target Neighborhood Hits	120	Shared Neighborhood Hits	29
SwissProt Accessions	P97333	Gene names	Nrp1, Nrp
Domain Architecture
Description	Neuropilin-1 precursor (A5 protein).

NOTC2_MOUSE
θ value	3.19293e-05 (rank : 22)	NC score	0.225887 (rank : 36)
Query Neighborhood Hits	162	Target Neighborhood Hits	1069	Shared Neighborhood Hits	138
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

ENTK_MOUSE
θ value	4.1701e-05 (rank : 23)	NC score	0.145550 (rank : 171)
Query Neighborhood Hits	162	Target Neighborhood Hits	338	Shared Neighborhood Hits	45
SwissProt Accessions	P97435	Gene names	Prss7, Entk
Domain Architecture
Description	Enteropeptidase (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

TRAF6_HUMAN
θ value	4.1701e-05 (rank : 24)	NC score	0.178401 (rank : 114)
Query Neighborhood Hits	162	Target Neighborhood Hits	267	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y4K3, Q8NEH5	Gene names	TRAF6, RNF85
Domain Architecture
Description	TNF receptor-associated factor 6 (Interleukin 1 signal transducer) (RING finger protein 85).

MAMC2_HUMAN
θ value	5.44631e-05 (rank : 25)	NC score	0.314254 (rank : 14)
Query Neighborhood Hits	162	Target Neighborhood Hits	31	Shared Neighborhood Hits	16
SwissProt Accessions	Q7Z304, Q5VW47, Q8WX43, Q96BM4	Gene names	MAMDC2
Domain Architecture
Description	MAM domain-containing protein 2 precursor.

NRP1_HUMAN
θ value	5.44631e-05 (rank : 26)	NC score	0.277458 (rank : 18)
Query Neighborhood Hits	162	Target Neighborhood Hits	119	Shared Neighborhood Hits	29
SwissProt Accessions	O14786, O60461, Q96IH5	Gene names	NRP1, NRP, VEGF165R
Domain Architecture
Description	Neuropilin-1 precursor (Vascular endothelial cell growth factor 165 receptor) (CD304 antigen).

DLK_HUMAN
θ value	0.000602161 (rank : 27)	NC score	0.244912 (rank : 20)
Query Neighborhood Hits	162	Target Neighborhood Hits	401	Shared Neighborhood Hits	129
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

TRAF2_HUMAN
θ value	0.000602161 (rank : 28)	NC score	0.202520 (rank : 68)
Query Neighborhood Hits	162	Target Neighborhood Hits	402	Shared Neighborhood Hits	16
SwissProt Accessions	Q12933, Q96NT2	Gene names	TRAF2, TRAP3
Domain Architecture
Description	TNF receptor-associated factor 2 (Tumor necrosis factor type 2 receptor-associated protein 3).

HABP2_MOUSE
θ value	0.000786445 (rank : 29)	NC score	0.137435 (rank : 192)
Query Neighborhood Hits	162	Target Neighborhood Hits	445	Shared Neighborhood Hits	121
SwissProt Accessions	Q8K0D2	Gene names	Habp2, Phbp
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

NOTC1_MOUSE
θ value	0.00102713 (rank : 30)	NC score	0.227346 (rank : 33)
Query Neighborhood Hits	162	Target Neighborhood Hits	916	Shared Neighborhood Hits	139
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

CSPG5_HUMAN
θ value	0.00134147 (rank : 31)	NC score	0.149840 (rank : 163)
Query Neighborhood Hits	162	Target Neighborhood Hits	199	Shared Neighborhood Hits	28
SwissProt Accessions	O95196, Q71M39, Q71M40	Gene names	CSPG5, CALEB, NGC
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 5 precursor (Neuroglycan C) (Acidic leucine-rich EGF-like domain-containing brain protein).

DLK_MOUSE
θ value	0.00134147 (rank : 32)	NC score	0.245122 (rank : 19)
Query Neighborhood Hits	162	Target Neighborhood Hits	374	Shared Neighborhood Hits	128
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

TRAF2_MOUSE
θ value	0.00175202 (rank : 33)	NC score	0.199152 (rank : 78)
Query Neighborhood Hits	162	Target Neighborhood Hits	394	Shared Neighborhood Hits	14
SwissProt Accessions	P39429, O54896	Gene names	Traf2
Domain Architecture
Description	TNF receptor-associated factor 2.

TRAF6_MOUSE
θ value	0.00228821 (rank : 34)	NC score	0.155818 (rank : 156)
Query Neighborhood Hits	162	Target Neighborhood Hits	255	Shared Neighborhood Hits	15
SwissProt Accessions	P70196, Q8BLV2	Gene names	Traf6
Domain Architecture
Description	TNF receptor-associated factor 6.

NOTC3_MOUSE
θ value	0.00298849 (rank : 35)	NC score	0.218690 (rank : 49)
Query Neighborhood Hits	162	Target Neighborhood Hits	975	Shared Neighborhood Hits	138
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC4_MOUSE
θ value	0.00390308 (rank : 36)	NC score	0.209864 (rank : 61)
Query Neighborhood Hits	162	Target Neighborhood Hits	872	Shared Neighborhood Hits	137
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

CSPG5_MOUSE
θ value	0.00509761 (rank : 37)	NC score	0.134551 (rank : 199)
Query Neighborhood Hits	162	Target Neighborhood Hits	211	Shared Neighborhood Hits	19
SwissProt Accessions	Q71M36, Q71M37, Q7TNT8, Q8BPJ5, Q9QY32	Gene names	Cspg5, Caleb, Ngc
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 5 precursor (Neuroglycan C) (Acidic leucine-rich EGF-like domain-containing brain protein).

EDIL3_HUMAN
θ value	0.00665767 (rank : 38)	NC score	0.234810 (rank : 24)
Query Neighborhood Hits	162	Target Neighborhood Hits	292	Shared Neighborhood Hits	133
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

NOTC1_HUMAN
θ value	0.00665767 (rank : 39)	NC score	0.221051 (rank : 47)
Query Neighborhood Hits	162	Target Neighborhood Hits	906	Shared Neighborhood Hits	139
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC3_HUMAN
θ value	0.00665767 (rank : 40)	NC score	0.215628 (rank : 55)
Query Neighborhood Hits	162	Target Neighborhood Hits	1062	Shared Neighborhood Hits	137
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

LRP1B_HUMAN
θ value	0.0113563 (rank : 41)	NC score	0.183214 (rank : 105)
Query Neighborhood Hits	162	Target Neighborhood Hits	602	Shared Neighborhood Hits	136
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

FBN1_MOUSE
θ value	0.0148317 (rank : 42)	NC score	0.226704 (rank : 35)
Query Neighborhood Hits	162	Target Neighborhood Hits	563	Shared Neighborhood Hits	128
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

MUC13_HUMAN
θ value	0.0148317 (rank : 43)	NC score	0.141653 (rank : 179)
Query Neighborhood Hits	162	Target Neighborhood Hits	164	Shared Neighborhood Hits	68
SwissProt Accessions	Q9H3R2, Q6UWD9, Q9NXT5	Gene names	MUC13, DRCC1, RECC
Domain Architecture	No domain graphic available
Description	Mucin-13 precursor (Down-regulated in colon cancer 1).

DLL1_HUMAN
θ value	0.0193708 (rank : 44)	NC score	0.231826 (rank : 28)
Query Neighborhood Hits	162	Target Neighborhood Hits	455	Shared Neighborhood Hits	135
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

TRAF1_HUMAN
θ value	0.0193708 (rank : 45)	NC score	0.182525 (rank : 106)
Query Neighborhood Hits	162	Target Neighborhood Hits	65	Shared Neighborhood Hits	13
SwissProt Accessions	Q13077, Q8NF13	Gene names	TRAF1, EBI6
Domain Architecture
Description	TNF receptor-associated factor 1 (Epstein-Barr virus-induced protein 6).

TRAF1_MOUSE
θ value	0.0193708 (rank : 46)	NC score	0.183769 (rank : 104)
Query Neighborhood Hits	162	Target Neighborhood Hits	52	Shared Neighborhood Hits	13
SwissProt Accessions	P39428	Gene names	Traf1
Domain Architecture
Description	TNF receptor-associated factor 1.

CRUM1_HUMAN
θ value	0.0252991 (rank : 47)	NC score	0.242805 (rank : 21)
Query Neighborhood Hits	162	Target Neighborhood Hits	457	Shared Neighborhood Hits	135
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

EDIL3_MOUSE
θ value	0.0252991 (rank : 48)	NC score	0.232314 (rank : 26)
Query Neighborhood Hits	162	Target Neighborhood Hits	317	Shared Neighborhood Hits	130
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

HABP2_HUMAN
θ value	0.0252991 (rank : 49)	NC score	0.131105 (rank : 204)
Query Neighborhood Hits	162	Target Neighborhood Hits	431	Shared Neighborhood Hits	118
SwissProt Accessions	Q14520, O00663	Gene names	HABP2, HGFAL, PHBP
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) (Hepatocyte growth factor activator-like protein) (Factor VII-activating protease) (Factor seven-activating protease) (FSAP) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

NOTC4_HUMAN
θ value	0.0252991 (rank : 50)	NC score	0.207714 (rank : 63)
Query Neighborhood Hits	162	Target Neighborhood Hits	905	Shared Neighborhood Hits	136
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

DLL3_MOUSE
θ value	0.0330416 (rank : 51)	NC score	0.238989 (rank : 22)
Query Neighborhood Hits	162	Target Neighborhood Hits	399	Shared Neighborhood Hits	129
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

MUC13_MOUSE
θ value	0.0330416 (rank : 52)	NC score	0.164414 (rank : 140)
Query Neighborhood Hits	162	Target Neighborhood Hits	447	Shared Neighborhood Hits	94
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

NRP2_HUMAN
θ value	0.0431538 (rank : 53)	NC score	0.229523 (rank : 29)
Query Neighborhood Hits	162	Target Neighborhood Hits	120	Shared Neighborhood Hits	29
SwissProt Accessions	O60462, O14820, O14821	Gene names	NRP2, VEGF165R2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

FATH_HUMAN
θ value	0.0563607 (rank : 54)	NC score	0.133006 (rank : 202)
Query Neighborhood Hits	162	Target Neighborhood Hits	570	Shared Neighborhood Hits	128
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

LTBP3_MOUSE
θ value	0.0563607 (rank : 55)	NC score	0.224145 (rank : 39)
Query Neighborhood Hits	162	Target Neighborhood Hits	475	Shared Neighborhood Hits	122
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

SLIT3_HUMAN
θ value	0.0563607 (rank : 56)	NC score	0.168854 (rank : 129)
Query Neighborhood Hits	162	Target Neighborhood Hits	682	Shared Neighborhood Hits	131
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

CELR3_MOUSE
θ value	0.0961366 (rank : 57)	NC score	0.111072 (rank : 245)
Query Neighborhood Hits	162	Target Neighborhood Hits	687	Shared Neighborhood Hits	128
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

DLL4_MOUSE
θ value	0.0961366 (rank : 58)	NC score	0.225698 (rank : 37)
Query Neighborhood Hits	162	Target Neighborhood Hits	440	Shared Neighborhood Hits	136
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

FA10_HUMAN
θ value	0.0961366 (rank : 59)	NC score	0.123796 (rank : 220)
Query Neighborhood Hits	162	Target Neighborhood Hits	431	Shared Neighborhood Hits	131
SwissProt Accessions	P00742, Q14340	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) (Stuart- Prower factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

FBN1_HUMAN
θ value	0.0961366 (rank : 60)	NC score	0.223085 (rank : 41)
Query Neighborhood Hits	162	Target Neighborhood Hits	557	Shared Neighborhood Hits	127
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

FBN2_MOUSE
θ value	0.0961366 (rank : 61)	NC score	0.221776 (rank : 44)
Query Neighborhood Hits	162	Target Neighborhood Hits	549	Shared Neighborhood Hits	129
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

LRP1B_MOUSE
θ value	0.0961366 (rank : 62)	NC score	0.174458 (rank : 120)
Query Neighborhood Hits	162	Target Neighborhood Hits	606	Shared Neighborhood Hits	134
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

TRAF3_HUMAN
θ value	0.0961366 (rank : 63)	NC score	0.160313 (rank : 151)
Query Neighborhood Hits	162	Target Neighborhood Hits	463	Shared Neighborhood Hits	15
SwissProt Accessions	Q13114, Q12990, Q13076, Q13947, Q6AZX1, Q9UNL1	Gene names	TRAF3, CAP1, CRAF1
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein) (LAP1) (CAP-1).

DLL3_HUMAN
θ value	0.125558 (rank : 64)	NC score	0.229174 (rank : 30)
Query Neighborhood Hits	162	Target Neighborhood Hits	419	Shared Neighborhood Hits	129
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

FBN2_HUMAN
θ value	0.125558 (rank : 65)	NC score	0.220917 (rank : 48)
Query Neighborhood Hits	162	Target Neighborhood Hits	560	Shared Neighborhood Hits	127
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

PGH2_HUMAN
θ value	0.125558 (rank : 66)	NC score	0.116985 (rank : 234)
Query Neighborhood Hits	162	Target Neighborhood Hits	103	Shared Neighborhood Hits	73
SwissProt Accessions	P35354, Q16876	Gene names	PTGS2, COX2
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II).

TRAF3_MOUSE
θ value	0.125558 (rank : 67)	NC score	0.159845 (rank : 153)
Query Neighborhood Hits	162	Target Neighborhood Hits	476	Shared Neighborhood Hits	16
SwissProt Accessions	Q60803, Q62380	Gene names	Traf3, Craf1, Trafamn
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (TRAFAMN).

DNER_MOUSE
θ value	0.163984 (rank : 68)	NC score	0.228854 (rank : 32)
Query Neighborhood Hits	162	Target Neighborhood Hits	413	Shared Neighborhood Hits	131
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

JAG1_HUMAN
θ value	0.163984 (rank : 69)	NC score	0.218676 (rank : 50)
Query Neighborhood Hits	162	Target Neighborhood Hits	514	Shared Neighborhood Hits	136
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

JAG1_MOUSE
θ value	0.163984 (rank : 70)	NC score	0.216807 (rank : 52)
Query Neighborhood Hits	162	Target Neighborhood Hits	518	Shared Neighborhood Hits	134
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

MATN2_HUMAN
θ value	0.163984 (rank : 71)	NC score	0.191228 (rank : 88)
Query Neighborhood Hits	162	Target Neighborhood Hits	365	Shared Neighborhood Hits	108
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

PROZ_MOUSE
θ value	0.163984 (rank : 72)	NC score	0.199400 (rank : 76)
Query Neighborhood Hits	162	Target Neighborhood Hits	410	Shared Neighborhood Hits	132
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

CELR2_HUMAN
θ value	0.21417 (rank : 73)	NC score	0.113262 (rank : 239)
Query Neighborhood Hits	162	Target Neighborhood Hits	657	Shared Neighborhood Hits	132
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

CSPG3_HUMAN
θ value	0.21417 (rank : 74)	NC score	0.164410 (rank : 141)
Query Neighborhood Hits	162	Target Neighborhood Hits	676	Shared Neighborhood Hits	120
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

CSPG3_MOUSE
θ value	0.21417 (rank : 75)	NC score	0.165593 (rank : 137)
Query Neighborhood Hits	162	Target Neighborhood Hits	657	Shared Neighborhood Hits	124
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

LTBP2_MOUSE
θ value	0.21417 (rank : 76)	NC score	0.217286 (rank : 51)
Query Neighborhood Hits	162	Target Neighborhood Hits	617	Shared Neighborhood Hits	129
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

CRUM1_MOUSE
θ value	0.279714 (rank : 77)	NC score	0.232293 (rank : 27)
Query Neighborhood Hits	162	Target Neighborhood Hits	444	Shared Neighborhood Hits	134
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

CSPG2_HUMAN
θ value	0.279714 (rank : 78)	NC score	0.164053 (rank : 142)
Query Neighborhood Hits	162	Target Neighborhood Hits	681	Shared Neighborhood Hits	122
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

CUBN_MOUSE
θ value	0.279714 (rank : 79)	NC score	0.294214 (rank : 15)
Query Neighborhood Hits	162	Target Neighborhood Hits	477	Shared Neighborhood Hits	137
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

DLL4_HUMAN
θ value	0.279714 (rank : 80)	NC score	0.221175 (rank : 46)
Query Neighborhood Hits	162	Target Neighborhood Hits	435	Shared Neighborhood Hits	131
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

DNER_HUMAN
θ value	0.279714 (rank : 81)	NC score	0.227240 (rank : 34)
Query Neighborhood Hits	162	Target Neighborhood Hits	460	Shared Neighborhood Hits	131
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

FA10_MOUSE
θ value	0.279714 (rank : 82)	NC score	0.121622 (rank : 226)
Query Neighborhood Hits	162	Target Neighborhood Hits	435	Shared Neighborhood Hits	132
SwissProt Accessions	O88947, O54740, Q99L32	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

NID1_HUMAN
θ value	0.279714 (rank : 83)	NC score	0.171878 (rank : 122)
Query Neighborhood Hits	162	Target Neighborhood Hits	329	Shared Neighborhood Hits	118
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

SLIT3_MOUSE
θ value	0.279714 (rank : 84)	NC score	0.163963 (rank : 143)
Query Neighborhood Hits	162	Target Neighborhood Hits	700	Shared Neighborhood Hits	130
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

ZAN_HUMAN
θ value	0.279714 (rank : 85)	NC score	0.165854 (rank : 136)
Query Neighborhood Hits	162	Target Neighborhood Hits	679	Shared Neighborhood Hits	134
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

CD97_HUMAN
θ value	0.365318 (rank : 86)	NC score	0.180720 (rank : 109)
Query Neighborhood Hits	162	Target Neighborhood Hits	353	Shared Neighborhood Hits	115
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

CELR1_HUMAN
θ value	0.365318 (rank : 87)	NC score	0.105836 (rank : 254)
Query Neighborhood Hits	162	Target Neighborhood Hits	613	Shared Neighborhood Hits	130
SwissProt Accessions	Q9NYQ6, O95722, Q5TH47, Q9BWQ5, Q9Y506, Q9Y526	Gene names	CELSR1, CDHF9, FMI2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor (Flamingo homolog 2) (hFmi2).

CELR3_HUMAN
θ value	0.365318 (rank : 88)	NC score	0.113138 (rank : 240)
Query Neighborhood Hits	162	Target Neighborhood Hits	680	Shared Neighborhood Hits	130
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

FBN3_HUMAN
θ value	0.365318 (rank : 89)	NC score	0.223367 (rank : 40)
Query Neighborhood Hits	162	Target Neighborhood Hits	543	Shared Neighborhood Hits	128
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

MMRN1_HUMAN
θ value	0.365318 (rank : 90)	NC score	0.106547 (rank : 251)
Query Neighborhood Hits	162	Target Neighborhood Hits	636	Shared Neighborhood Hits	101
SwissProt Accessions	Q13201, Q6P3T8	Gene names	MMRN1, ECM, EMILIN4, MMRN
Domain Architecture
Description	Multimerin-1 precursor (Endothelial cell multimerin 1) (EMILIN-4) (Elastin microfibril interface located protein 4) (Elastin microfibril interfacer 4).

CELR2_MOUSE
θ value	0.47712 (rank : 91)	NC score	0.104045 (rank : 261)
Query Neighborhood Hits	162	Target Neighborhood Hits	584	Shared Neighborhood Hits	126
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

CRUM2_HUMAN
θ value	0.47712 (rank : 92)	NC score	0.228874 (rank : 31)
Query Neighborhood Hits	162	Target Neighborhood Hits	453	Shared Neighborhood Hits	135
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

C1QR1_MOUSE
θ value	0.62314 (rank : 93)	NC score	0.222362 (rank : 43)
Query Neighborhood Hits	162	Target Neighborhood Hits	342	Shared Neighborhood Hits	126
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

EGF_MOUSE
θ value	0.62314 (rank : 94)	NC score	0.193866 (rank : 85)
Query Neighborhood Hits	162	Target Neighborhood Hits	358	Shared Neighborhood Hits	129
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

PGH2_MOUSE
θ value	0.62314 (rank : 95)	NC score	0.119453 (rank : 231)
Query Neighborhood Hits	162	Target Neighborhood Hits	113	Shared Neighborhood Hits	81
SwissProt Accessions	Q05769	Gene names	Ptgs2, Cox-2, Cox2, Pghs-b, Tis10
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II) (Glucocorticoid- regulated inflammatory cyclooxygenase) (Gripghs) (TIS10 protein) (Macrophage activation-associated marker protein P71/73) (PES-2).

SLIT1_MOUSE
θ value	0.62314 (rank : 96)	NC score	0.171374 (rank : 124)
Query Neighborhood Hits	162	Target Neighborhood Hits	715	Shared Neighborhood Hits	136
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

CSPG2_MOUSE
θ value	0.813845 (rank : 97)	NC score	0.164858 (rank : 139)
Query Neighborhood Hits	162	Target Neighborhood Hits	711	Shared Neighborhood Hits	124
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

FA12_HUMAN
θ value	0.813845 (rank : 98)	NC score	0.095254 (rank : 286)
Query Neighborhood Hits	162	Target Neighborhood Hits	425	Shared Neighborhood Hits	107
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

FA9_HUMAN
θ value	0.813845 (rank : 99)	NC score	0.115482 (rank : 236)
Query Neighborhood Hits	162	Target Neighborhood Hits	421	Shared Neighborhood Hits	131
SwissProt Accessions	P00740	Gene names	F9
Domain Architecture
Description	Coagulation factor IX precursor (EC 3.4.21.22) (Christmas factor) (Plasma thromboplastin component) (PTC) [Contains: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain].

FBLN3_MOUSE
θ value	0.813845 (rank : 100)	NC score	0.193313 (rank : 86)
Query Neighborhood Hits	162	Target Neighborhood Hits	279	Shared Neighborhood Hits	113
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

HGFA_HUMAN
θ value	0.813845 (rank : 101)	NC score	0.103578 (rank : 262)
Query Neighborhood Hits	162	Target Neighborhood Hits	436	Shared Neighborhood Hits	116
SwissProt Accessions	Q04756, Q14726	Gene names	HGFAC
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

JAG2_HUMAN
θ value	0.813845 (rank : 102)	NC score	0.211645 (rank : 59)
Query Neighborhood Hits	162	Target Neighborhood Hits	491	Shared Neighborhood Hits	131
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

JAG2_MOUSE
θ value	0.813845 (rank : 103)	NC score	0.212671 (rank : 58)
Query Neighborhood Hits	162	Target Neighborhood Hits	504	Shared Neighborhood Hits	132
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

NID1_MOUSE
θ value	0.813845 (rank : 104)	NC score	0.171555 (rank : 123)
Query Neighborhood Hits	162	Target Neighborhood Hits	335	Shared Neighborhood Hits	118
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

DLL1_MOUSE
θ value	1.06291 (rank : 105)	NC score	0.223013 (rank : 42)
Query Neighborhood Hits	162	Target Neighborhood Hits	456	Shared Neighborhood Hits	135
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

EMR2_HUMAN
θ value	1.06291 (rank : 106)	NC score	0.177463 (rank : 116)
Query Neighborhood Hits	162	Target Neighborhood Hits	345	Shared Neighborhood Hits	115
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

FBLN2_HUMAN
θ value	1.06291 (rank : 107)	NC score	0.194721 (rank : 84)
Query Neighborhood Hits	162	Target Neighborhood Hits	392	Shared Neighborhood Hits	114
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

LRP8_HUMAN
θ value	1.06291 (rank : 108)	NC score	0.148578 (rank : 166)
Query Neighborhood Hits	162	Target Neighborhood Hits	346	Shared Neighborhood Hits	108
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LTBP3_HUMAN
θ value	1.06291 (rank : 109)	NC score	0.210713 (rank : 60)
Query Neighborhood Hits	162	Target Neighborhood Hits	502	Shared Neighborhood Hits	121
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

NID2_MOUSE
θ value	1.06291 (rank : 110)	NC score	0.182251 (rank : 107)
Query Neighborhood Hits	162	Target Neighborhood Hits	338	Shared Neighborhood Hits	120
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

NRG2_MOUSE
θ value	1.06291 (rank : 111)	NC score	0.104079 (rank : 260)
Query Neighborhood Hits	162	Target Neighborhood Hits	392	Shared Neighborhood Hits	83
SwissProt Accessions	P56974	Gene names	Nrg2
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Divergent of neuregulin 1) (DON-1)].

PGCB_MOUSE
θ value	1.06291 (rank : 112)	NC score	0.110105 (rank : 247)
Query Neighborhood Hits	162	Target Neighborhood Hits	459	Shared Neighborhood Hits	110
SwissProt Accessions	Q61361	Gene names	Bcan
Domain Architecture
Description	Brevican core protein precursor.

ZAN_MOUSE
θ value	1.06291 (rank : 113)	NC score	0.183838 (rank : 102)
Query Neighborhood Hits	162	Target Neighborhood Hits	808	Shared Neighborhood Hits	141
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

CELR1_MOUSE
θ value	1.38821 (rank : 114)	NC score	0.105894 (rank : 252)
Query Neighborhood Hits	162	Target Neighborhood Hits	617	Shared Neighborhood Hits	127
SwissProt Accessions	O35161	Gene names	Celsr1
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor.

CO7_HUMAN
θ value	1.38821 (rank : 115)	NC score	0.057039 (rank : 418)
Query Neighborhood Hits	162	Target Neighborhood Hits	278	Shared Neighborhood Hits	66
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

MFGM_HUMAN
θ value	1.38821 (rank : 116)	NC score	0.139277 (rank : 187)
Query Neighborhood Hits	162	Target Neighborhood Hits	150	Shared Neighborhood Hits	96
SwissProt Accessions	Q08431	Gene names	MFGE8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (HMFG) (Breast epithelial antigen BA46) (MFGM) [Contains: Lactadherin short form; Medin].

NRX3A_HUMAN
θ value	1.38821 (rank : 117)	NC score	0.098600 (rank : 273)
Query Neighborhood Hits	162	Target Neighborhood Hits	164	Shared Neighborhood Hits	93
SwissProt Accessions	Q9Y4C0, O95378, Q9NS47, Q9P1V3, Q9P1V6, Q9UIE2, Q9UIE3, Q9ULA5, Q9Y486	Gene names	NRXN3, KIAA0743
Domain Architecture
Description	Neurexin-3-alpha precursor (Neurexin III-alpha).

PROS_MOUSE
θ value	1.38821 (rank : 118)	NC score	0.214392 (rank : 56)
Query Neighborhood Hits	162	Target Neighborhood Hits	330	Shared Neighborhood Hits	124
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

SLIT1_HUMAN
θ value	1.38821 (rank : 119)	NC score	0.166911 (rank : 134)
Query Neighborhood Hits	162	Target Neighborhood Hits	700	Shared Neighborhood Hits	132
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

VASN_HUMAN
θ value	1.38821 (rank : 120)	NC score	0.057092 (rank : 417)
Query Neighborhood Hits	162	Target Neighborhood Hits	449	Shared Neighborhood Hits	84
SwissProt Accessions	Q6EMK4, Q6UXL4, Q6UXL5, Q96CX1	Gene names	VASN, SLITL2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

EGFL9_HUMAN
θ value	1.81305 (rank : 121)	NC score	0.216307 (rank : 54)
Query Neighborhood Hits	162	Target Neighborhood Hits	365	Shared Neighborhood Hits	127
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

EMR1_HUMAN
θ value	1.81305 (rank : 122)	NC score	0.170291 (rank : 128)
Query Neighborhood Hits	162	Target Neighborhood Hits	382	Shared Neighborhood Hits	116
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

PGCB_HUMAN
θ value	1.81305 (rank : 123)	NC score	0.103530 (rank : 263)
Query Neighborhood Hits	162	Target Neighborhood Hits	478	Shared Neighborhood Hits	107
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

SLIT2_HUMAN
θ value	1.81305 (rank : 124)	NC score	0.167113 (rank : 132)
Query Neighborhood Hits	162	Target Neighborhood Hits	708	Shared Neighborhood Hits	134
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

SLIT2_MOUSE
θ value	1.81305 (rank : 125)	NC score	0.163311 (rank : 144)
Query Neighborhood Hits	162	Target Neighborhood Hits	684	Shared Neighborhood Hits	130
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

AGRIN_HUMAN
θ value	2.36792 (rank : 126)	NC score	0.153127 (rank : 159)
Query Neighborhood Hits	162	Target Neighborhood Hits	582	Shared Neighborhood Hits	124
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

CUBN_HUMAN
θ value	2.36792 (rank : 127)	NC score	0.289640 (rank : 16)
Query Neighborhood Hits	162	Target Neighborhood Hits	482	Shared Neighborhood Hits	139
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

EGF_HUMAN
θ value	2.36792 (rank : 128)	NC score	0.177771 (rank : 115)
Query Neighborhood Hits	162	Target Neighborhood Hits	343	Shared Neighborhood Hits	120
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

LTB1L_MOUSE
θ value	2.36792 (rank : 129)	NC score	0.205321 (rank : 66)
Query Neighborhood Hits	162	Target Neighborhood Hits	514	Shared Neighborhood Hits	127
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_MOUSE
θ value	2.36792 (rank : 130)	NC score	0.205544 (rank : 65)
Query Neighborhood Hits	162	Target Neighborhood Hits	479	Shared Neighborhood Hits	123
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTBP2_HUMAN
θ value	2.36792 (rank : 131)	NC score	0.205852 (rank : 64)
Query Neighborhood Hits	162	Target Neighborhood Hits	552	Shared Neighborhood Hits	130
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LYAM3_MOUSE
θ value	3.0926 (rank : 132)	NC score	0.107338 (rank : 248)
Query Neighborhood Hits	162	Target Neighborhood Hits	390	Shared Neighborhood Hits	120
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

MATN2_MOUSE
θ value	3.0926 (rank : 133)	NC score	0.187789 (rank : 92)
Query Neighborhood Hits	162	Target Neighborhood Hits	356	Shared Neighborhood Hits	107
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

MFGM_MOUSE
θ value	3.0926 (rank : 134)	NC score	0.176303 (rank : 117)
Query Neighborhood Hits	162	Target Neighborhood Hits	233	Shared Neighborhood Hits	110
SwissProt Accessions	P21956, P97800, Q3TBN5, Q9R1X9, Q9WTS3	Gene names	Mfge8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (MFGM) (Sperm surface protein SP47) (MP47).

PROS_HUMAN
θ value	3.0926 (rank : 135)	NC score	0.221646 (rank : 45)
Query Neighborhood Hits	162	Target Neighborhood Hits	340	Shared Neighborhood Hits	124
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

EMR1_MOUSE
θ value	4.03905 (rank : 136)	NC score	0.160559 (rank : 149)
Query Neighborhood Hits	162	Target Neighborhood Hits	349	Shared Neighborhood Hits	113
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

NID2_HUMAN
θ value	4.03905 (rank : 137)	NC score	0.179039 (rank : 113)
Query Neighborhood Hits	162	Target Neighborhood Hits	456	Shared Neighborhood Hits	122
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

NRX1A_HUMAN
θ value	4.03905 (rank : 138)	NC score	0.096762 (rank : 279)
Query Neighborhood Hits	162	Target Neighborhood Hits	170	Shared Neighborhood Hits	86
SwissProt Accessions	Q9ULB1, O60323, Q53TJ9, Q53TQ1, Q9C079, Q9C080, Q9C081, Q9H3M2, Q9UDM6	Gene names	NRXN1, KIAA0578
Domain Architecture
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

CATW_MOUSE
θ value	5.27518 (rank : 139)	NC score	0.006899 (rank : 436)
Query Neighborhood Hits	162	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	P56203	Gene names	Ctsw
Domain Architecture
Description	Cathepsin W precursor (EC 3.4.22.-) (Lymphopain).

FAT2_HUMAN
θ value	5.27518 (rank : 140)	NC score	0.094479 (rank : 287)
Query Neighborhood Hits	162	Target Neighborhood Hits	507	Shared Neighborhood Hits	110
SwissProt Accessions	Q9NYQ8, O75091, Q9NSR7	Gene names	FAT2, CDHF8, KIAA0811, MEGF1
Domain Architecture
Description	Protocadherin Fat 2 precursor (hFat2) (Multiple epidermal growth factor-like domains 1).

FBLN3_HUMAN
θ value	5.27518 (rank : 141)	NC score	0.189016 (rank : 89)
Query Neighborhood Hits	162	Target Neighborhood Hits	293	Shared Neighborhood Hits	113
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

GAS6_MOUSE
θ value	5.27518 (rank : 142)	NC score	0.201620 (rank : 70)
Query Neighborhood Hits	162	Target Neighborhood Hits	343	Shared Neighborhood Hits	125
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

NRX1A_MOUSE
θ value	5.27518 (rank : 143)	NC score	0.096002 (rank : 281)
Query Neighborhood Hits	162	Target Neighborhood Hits	164	Shared Neighborhood Hits	86
SwissProt Accessions	Q9CS84, O88722, Q80Y87, Q8CHE6	Gene names	Nrxn1, Kiaa0578
Domain Architecture	No domain graphic available
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

RECK_HUMAN
θ value	5.27518 (rank : 144)	NC score	0.060230 (rank : 403)
Query Neighborhood Hits	162	Target Neighborhood Hits	189	Shared Neighborhood Hits	51
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

ACS2L_MOUSE
θ value	6.88961 (rank : 145)	NC score	0.007809 (rank : 435)
Query Neighborhood Hits	162	Target Neighborhood Hits	35	Shared Neighborhood Hits	2
SwissProt Accessions	Q99NB1, Q8K0M6	Gene names	Acss1, Acas2, Acas2l
Domain Architecture
Description	Acetyl-coenzyme A synthetase 2-like, mitochondrial precursor (EC 6.2.1.1) (Acetate--CoA ligase 2) (Acetyl-CoA synthetase 2) (AceCS2) (Acyl-CoA synthetase short-chain family member 1).

CNTP3_HUMAN
θ value	6.88961 (rank : 146)	NC score	0.087201 (rank : 307)
Query Neighborhood Hits	162	Target Neighborhood Hits	195	Shared Neighborhood Hits	97
SwissProt Accessions	Q9BZ76, Q9C0E9	Gene names	CNTNAP3, CASPR3, KIAA1714
Domain Architecture
Description	Contactin-associated protein-like 3 precursor (Cell recognition molecule Caspr3).

HGFA_MOUSE
θ value	6.88961 (rank : 147)	NC score	0.100873 (rank : 268)
Query Neighborhood Hits	162	Target Neighborhood Hits	419	Shared Neighborhood Hits	117
SwissProt Accessions	Q9R098, Q9JKV4	Gene names	Hgfac
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

LRP8_MOUSE
θ value	6.88961 (rank : 148)	NC score	0.144064 (rank : 177)
Query Neighborhood Hits	162	Target Neighborhood Hits	385	Shared Neighborhood Hits	108
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

PROZ_HUMAN
θ value	6.88961 (rank : 149)	NC score	0.185629 (rank : 96)
Query Neighborhood Hits	162	Target Neighborhood Hits	422	Shared Neighborhood Hits	129
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

WIF1_HUMAN
θ value	6.88961 (rank : 150)	NC score	0.180252 (rank : 111)
Query Neighborhood Hits	162	Target Neighborhood Hits	392	Shared Neighborhood Hits	120
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

CD248_HUMAN
θ value	8.99809 (rank : 151)	NC score	0.152921 (rank : 160)
Query Neighborhood Hits	162	Target Neighborhood Hits	679	Shared Neighborhood Hits	110
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

EGFL9_MOUSE
θ value	8.99809 (rank : 152)	NC score	0.212903 (rank : 57)
Query Neighborhood Hits	162	Target Neighborhood Hits	379	Shared Neighborhood Hits	127
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

FA7_MOUSE
θ value	8.99809 (rank : 153)	NC score	0.098177 (rank : 275)
Query Neighborhood Hits	162	Target Neighborhood Hits	374	Shared Neighborhood Hits	124
SwissProt Accessions	P70375, Q61109	Gene names	F7, Cf7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) [Contains: Factor VII light chain; Factor VII heavy chain].

FBLN5_HUMAN
θ value	8.99809 (rank : 154)	NC score	0.195900 (rank : 82)
Query Neighborhood Hits	162	Target Neighborhood Hits	329	Shared Neighborhood Hits	116
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

LTB1L_HUMAN
θ value	8.99809 (rank : 155)	NC score	0.199618 (rank : 74)
Query Neighborhood Hits	162	Target Neighborhood Hits	553	Shared Neighborhood Hits	126
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1S_HUMAN
θ value	8.99809 (rank : 156)	NC score	0.199659 (rank : 73)
Query Neighborhood Hits	162	Target Neighborhood Hits	502	Shared Neighborhood Hits	126
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

NTNG2_HUMAN
θ value	8.99809 (rank : 157)	NC score	0.097237 (rank : 277)
Query Neighborhood Hits	162	Target Neighborhood Hits	276	Shared Neighborhood Hits	101
SwissProt Accessions	Q96CW9, Q6UXY0, Q96JH0	Gene names	NTNG2, KIAA1857, LMNT2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

PGH1_MOUSE
θ value	8.99809 (rank : 158)	NC score	0.090237 (rank : 298)
Query Neighborhood Hits	162	Target Neighborhood Hits	100	Shared Neighborhood Hits	67
SwissProt Accessions	P22437	Gene names	Ptgs1, Cox-1, Cox1
Domain Architecture
Description	Prostaglandin G/H synthase 1 precursor (EC 1.14.99.1) (Cyclooxygenase- 1) (COX-1) (Prostaglandin-endoperoxide synthase 1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1).

STAB2_HUMAN
θ value	8.99809 (rank : 159)	NC score	0.144924 (rank : 172)
Query Neighborhood Hits	162	Target Neighborhood Hits	534	Shared Neighborhood Hits	123
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

VLDLR_HUMAN
θ value	8.99809 (rank : 160)	NC score	0.140421 (rank : 184)
Query Neighborhood Hits	162	Target Neighborhood Hits	383	Shared Neighborhood Hits	109
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

VLDLR_MOUSE
θ value	8.99809 (rank : 161)	NC score	0.141031 (rank : 182)
Query Neighborhood Hits	162	Target Neighborhood Hits	360	Shared Neighborhood Hits	108
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

WIF1_MOUSE
θ value	8.99809 (rank : 162)	NC score	0.181938 (rank : 108)
Query Neighborhood Hits	162	Target Neighborhood Hits	393	Shared Neighborhood Hits	118
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

ASTN_HUMAN
θ value	θ > 10 (rank : 163)	NC score	0.052815 (rank : 430)
Query Neighborhood Hits	162	Target Neighborhood Hits	105	Shared Neighborhood Hits	44
SwissProt Accessions	O14525, O60799, Q5W0V7, Q5W0V8	Gene names	ASTN, ASTN1, KIAA0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor.

ATRN_HUMAN
θ value	θ > 10 (rank : 164)	NC score	0.159676 (rank : 154)
Query Neighborhood Hits	162	Target Neighborhood Hits	525	Shared Neighborhood Hits	105
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

ATRN_MOUSE
θ value	θ > 10 (rank : 165)	NC score	0.157983 (rank : 155)
Query Neighborhood Hits	162	Target Neighborhood Hits	519	Shared Neighborhood Hits	106
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

C1QR1_HUMAN
θ value	θ > 10 (rank : 166)	NC score	0.195606 (rank : 83)
Query Neighborhood Hits	162	Target Neighborhood Hits	493	Shared Neighborhood Hits	122
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

C1RA_MOUSE
θ value	θ > 10 (rank : 167)	NC score	0.128653 (rank : 208)
Query Neighborhood Hits	162	Target Neighborhood Hits	379	Shared Neighborhood Hits	90
SwissProt Accessions	Q8CG16, Q99KI6, Q9ET60	Gene names	C1ra, C1r
Domain Architecture
Description	Complement C1r-A subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-A subcomponent) [Contains: Complement C1r-A subcomponent heavy chain; Complement C1r-A subcomponent light chain].

C1RB_MOUSE
θ value	θ > 10 (rank : 168)	NC score	0.126763 (rank : 212)
Query Neighborhood Hits	162	Target Neighborhood Hits	380	Shared Neighborhood Hits	89
SwissProt Accessions	Q8CFG9	Gene names	C1rb, C1r
Domain Architecture	No domain graphic available
Description	Complement C1r-B subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-B subcomponent) [Contains: Complement C1r-B subcomponent heavy chain; Complement C1r-B subcomponent light chain].

C1R_HUMAN
θ value	θ > 10 (rank : 169)	NC score	0.126285 (rank : 214)
Query Neighborhood Hits	162	Target Neighborhood Hits	364	Shared Neighborhood Hits	80
SwissProt Accessions	P00736, Q8J012	Gene names	C1R
Domain Architecture
Description	Complement C1r subcomponent precursor (EC 3.4.21.41) (Complement component 1, r subcomponent) [Contains: Complement C1r subcomponent heavy chain; Complement C1r subcomponent light chain].

C1S_HUMAN
θ value	θ > 10 (rank : 170)	NC score	0.122581 (rank : 222)
Query Neighborhood Hits	162	Target Neighborhood Hits	359	Shared Neighborhood Hits	89
SwissProt Accessions	P09871, Q9UCU7, Q9UCU8, Q9UCU9, Q9UCV0, Q9UCV1, Q9UCV2, Q9UCV3, Q9UCV4, Q9UCV5, Q9UM14	Gene names	C1S
Domain Architecture
Description	Complement C1s subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s subcomponent heavy chain; Complement C1s subcomponent light chain].

CD248_MOUSE
θ value	θ > 10 (rank : 171)	NC score	0.153928 (rank : 157)
Query Neighborhood Hits	162	Target Neighborhood Hits	578	Shared Neighborhood Hits	108
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

CD97_MOUSE
θ value	θ > 10 (rank : 172)	NC score	0.138892 (rank : 189)
Query Neighborhood Hits	162	Target Neighborhood Hits	295	Shared Neighborhood Hits	106
SwissProt Accessions	Q9Z0M6, Q923A1, Q9CVI5, Q9JLQ8	Gene names	Cd97
Domain Architecture
Description	CD97 antigen precursor.

CFC1_HUMAN
θ value	θ > 10 (rank : 173)	NC score	0.104888 (rank : 257)
Query Neighborhood Hits	162	Target Neighborhood Hits	148	Shared Neighborhood Hits	81
SwissProt Accessions	Q9GZR3, Q53T05	Gene names	CFC1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

CFC1_MOUSE
θ value	θ > 10 (rank : 174)	NC score	0.101756 (rank : 266)
Query Neighborhood Hits	162	Target Neighborhood Hits	125	Shared Neighborhood Hits	78
SwissProt Accessions	P97766, Q496U5, Q9JIB7	Gene names	Cfc1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

CLC14_HUMAN
θ value	θ > 10 (rank : 175)	NC score	0.089714 (rank : 300)
Query Neighborhood Hits	162	Target Neighborhood Hits	143	Shared Neighborhood Hits	70
SwissProt Accessions	Q86T13, Q6PWT6, Q8N5V5	Gene names	CLEC14A, C14orf27, EGFR5
Domain Architecture
Description	C-type lectin domain family 14 member A precursor (Epidermal growth factor receptor 5) (EGFR-5).

CLC14_MOUSE
θ value	θ > 10 (rank : 176)	NC score	0.092251 (rank : 293)
Query Neighborhood Hits	162	Target Neighborhood Hits	120	Shared Neighborhood Hits	67
SwissProt Accessions	Q8VCP9, Q3TP72, Q9CXA8, Q9D624, Q9DC55	Gene names	Clec14a
Domain Architecture
Description	C-type lectin domain family 14 member A precursor.

CNTP1_HUMAN
θ value	θ > 10 (rank : 177)	NC score	0.075528 (rank : 355)
Query Neighborhood Hits	162	Target Neighborhood Hits	196	Shared Neighborhood Hits	91
SwissProt Accessions	P78357	Gene names	CNTNAP1, CASPR, NRXN4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (p190).

CNTP1_MOUSE
θ value	θ > 10 (rank : 178)	NC score	0.073534 (rank : 363)
Query Neighborhood Hits	162	Target Neighborhood Hits	183	Shared Neighborhood Hits	89
SwissProt Accessions	O54991	Gene names	Cntnap1, Nrxn4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (Paranodin) (NCP1) (MHDNIV).

CNTP2_HUMAN
θ value	θ > 10 (rank : 179)	NC score	0.086829 (rank : 309)
Query Neighborhood Hits	162	Target Neighborhood Hits	199	Shared Neighborhood Hits	103
SwissProt Accessions	Q9UHC6, Q52LV1, Q5H9Q7, Q9UQ12	Gene names	CNTNAP2, CASPR2, KIAA0868
Domain Architecture
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

CNTP2_MOUSE
θ value	θ > 10 (rank : 180)	NC score	0.086534 (rank : 311)
Query Neighborhood Hits	162	Target Neighborhood Hits	194	Shared Neighborhood Hits	100
SwissProt Accessions	Q9CPW0, Q6P2K4, Q6ZQ31	Gene names	Cntnap2, Kiaa0868
Domain Architecture	No domain graphic available
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

CNTP4_HUMAN
θ value	θ > 10 (rank : 181)	NC score	0.082178 (rank : 324)
Query Neighborhood Hits	162	Target Neighborhood Hits	187	Shared Neighborhood Hits	91
SwissProt Accessions	Q9C0A0	Gene names	CNTNAP4, CASPR4, KIAA1763
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

CNTP4_MOUSE
θ value	θ > 10 (rank : 182)	NC score	0.084423 (rank : 316)
Query Neighborhood Hits	162	Target Neighborhood Hits	193	Shared Neighborhood Hits	94
SwissProt Accessions	Q99P47	Gene names	Cntnap4, Caspr4
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

CO8B_MOUSE
θ value	θ > 10 (rank : 183)	NC score	0.059077 (rank : 409)
Query Neighborhood Hits	162	Target Neighborhood Hits	224	Shared Neighborhood Hits	62
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

COMP_HUMAN
θ value	θ > 10 (rank : 184)	NC score	0.116152 (rank : 235)
Query Neighborhood Hits	162	Target Neighborhood Hits	258	Shared Neighborhood Hits	101
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

COMP_MOUSE
θ value	θ > 10 (rank : 185)	NC score	0.124595 (rank : 219)
Query Neighborhood Hits	162	Target Neighborhood Hits	290	Shared Neighborhood Hits	104
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

CORIN_HUMAN
θ value	θ > 10 (rank : 186)	NC score	0.058346 (rank : 412)
Query Neighborhood Hits	162	Target Neighborhood Hits	453	Shared Neighborhood Hits	75
SwissProt Accessions	Q9Y5Q5, Q9UHY2	Gene names	CORIN, CRN, TMPRSS10
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Heart-specific serine proteinase ATC2) (Transmembrane protease, serine 10).

CORIN_MOUSE
θ value	θ > 10 (rank : 187)	NC score	0.052537 (rank : 433)
Query Neighborhood Hits	162	Target Neighborhood Hits	451	Shared Neighborhood Hits	76
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

CRAC1_HUMAN
θ value	θ > 10 (rank : 188)	NC score	0.072739 (rank : 371)
Query Neighborhood Hits	162	Target Neighborhood Hits	111	Shared Neighborhood Hits	51
SwissProt Accessions	Q9NQ79, Q8N4H6, Q8TE52, Q9NQ78, Q9NQ80, Q9NW46	Gene names	CRTAC1, ASPIC1, CEP68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

CRAC1_MOUSE
θ value	θ > 10 (rank : 189)	NC score	0.073159 (rank : 367)
Query Neighborhood Hits	162	Target Neighborhood Hits	112	Shared Neighborhood Hits	52
SwissProt Accessions	Q8R555, Q3UF32, Q8BMF1, Q8R3V8	Gene names	Crtac1, Aspic1, Cep68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (CRTAC1-B protein) (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

CREL1_HUMAN
θ value	θ > 10 (rank : 190)	NC score	0.146827 (rank : 167)
Query Neighborhood Hits	162	Target Neighborhood Hits	441	Shared Neighborhood Hits	105
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

CREL1_MOUSE
θ value	θ > 10 (rank : 191)	NC score	0.141248 (rank : 181)
Query Neighborhood Hits	162	Target Neighborhood Hits	524	Shared Neighborhood Hits	106
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

CRIM1_HUMAN
θ value	θ > 10 (rank : 192)	NC score	0.071303 (rank : 377)
Query Neighborhood Hits	162	Target Neighborhood Hits	362	Shared Neighborhood Hits	68
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

CS1A_MOUSE
θ value	θ > 10 (rank : 193)	NC score	0.125851 (rank : 218)
Query Neighborhood Hits	162	Target Neighborhood Hits	360	Shared Neighborhood Hits	86
SwissProt Accessions	Q8CG14, Q8BJC4, Q8CH28, Q8VBY4	Gene names	C1sa, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-A subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-A subcomponent heavy chain; Complement C1s-A subcomponent light chain].

CS1B_MOUSE
θ value	θ > 10 (rank : 194)	NC score	0.125907 (rank : 216)
Query Neighborhood Hits	162	Target Neighborhood Hits	361	Shared Neighborhood Hits	86
SwissProt Accessions	Q8CFG8	Gene names	C1sb, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-B subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-B subcomponent heavy chain; Complement C1s-B subcomponent light chain].

CSMD1_HUMAN
θ value	θ > 10 (rank : 195)	NC score	0.136461 (rank : 194)
Query Neighborhood Hits	162	Target Neighborhood Hits	176	Shared Neighborhood Hits	30
SwissProt Accessions	Q96PZ7, Q96QU9, Q96RM4	Gene names	CSMD1, KIAA1890
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

CSMD1_MOUSE
θ value	θ > 10 (rank : 196)	NC score	0.134001 (rank : 200)
Query Neighborhood Hits	162	Target Neighborhood Hits	193	Shared Neighborhood Hits	32
SwissProt Accessions	Q923L3, Q8BUV1, Q8BYQ3	Gene names	Csmd1
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

CSMD2_HUMAN
θ value	θ > 10 (rank : 197)	NC score	0.138355 (rank : 190)
Query Neighborhood Hits	162	Target Neighborhood Hits	188	Shared Neighborhood Hits	30
SwissProt Accessions	Q7Z408, Q5VT59, Q8N963, Q96Q03, Q9H4V7, Q9H4V8, Q9H4V9, Q9H4W0, Q9H4W1, Q9H4W2, Q9H4W3, Q9H4W4, Q9HCY5, Q9HCY6, Q9HCY7	Gene names	CSMD2, KIAA1884
Domain Architecture
Description	CUB and sushi domain-containing protein 2 (CUB and sushi multiple domains protein 2).

CSMD3_HUMAN
θ value	θ > 10 (rank : 198)	NC score	0.135662 (rank : 196)
Query Neighborhood Hits	162	Target Neighborhood Hits	199	Shared Neighborhood Hits	36
SwissProt Accessions	Q7Z407, Q96PZ3	Gene names	CSMD3, KIAA1894
Domain Architecture
Description	CUB and sushi domain-containing protein 3 precursor (CUB and sushi multiple domains protein 3).

CUZD1_HUMAN
θ value	θ > 10 (rank : 199)	NC score	0.149228 (rank : 164)
Query Neighborhood Hits	162	Target Neighborhood Hits	89	Shared Neighborhood Hits	13
SwissProt Accessions	Q86UP6, Q7Z660, Q7Z661, Q86SG1, Q86UP5, Q9HAR7	Gene names	CUZD1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Transmembrane protein UO-44).

CUZD1_MOUSE
θ value	θ > 10 (rank : 200)	NC score	0.144873 (rank : 173)
Query Neighborhood Hits	162	Target Neighborhood Hits	91	Shared Neighborhood Hits	13
SwissProt Accessions	P70412, Q9CTZ7	Gene names	Cuzd1, Itmap1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Integral membrane-associated protein 1).

DCBD1_HUMAN
θ value	θ > 10 (rank : 201)	NC score	0.117240 (rank : 232)
Query Neighborhood Hits	162	Target Neighborhood Hits	110	Shared Neighborhood Hits	18
SwissProt Accessions	Q8N8Z6, Q5H992, Q8IYK5, Q8N7L9, Q96NH2	Gene names	DCBLD1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

DCBD1_MOUSE
θ value	θ > 10 (rank : 202)	NC score	0.106772 (rank : 250)
Query Neighborhood Hits	162	Target Neighborhood Hits	89	Shared Neighborhood Hits	13
SwissProt Accessions	Q9D4J3, Q8R327, Q9D696	Gene names	Dcbld1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

DCBD2_HUMAN
θ value	θ > 10 (rank : 203)	NC score	0.130064 (rank : 206)
Query Neighborhood Hits	162	Target Neighborhood Hits	118	Shared Neighborhood Hits	18
SwissProt Accessions	Q96PD2, Q8N6M4, Q8TDX2	Gene names	DCBLD2, CLCP1, ESDN
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein) (CUB, LCCL and coagulation factor V/VIII-homology domains protein 1).

DCBD2_MOUSE
θ value	θ > 10 (rank : 204)	NC score	0.128028 (rank : 209)
Query Neighborhood Hits	162	Target Neighborhood Hits	113	Shared Neighborhood Hits	18
SwissProt Accessions	Q91ZV3, Q8BKI4	Gene names	Dcbld2, Esdn
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein).

DMBT1_HUMAN
θ value	θ > 10 (rank : 205)	NC score	0.117098 (rank : 233)
Query Neighborhood Hits	162	Target Neighborhood Hits	152	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UGM3, Q59EX0, Q5JR26, Q6MZN4, Q96DU4, Q9UGM2, Q9UJ57, Q9UKJ4, Q9Y211, Q9Y4V9	Gene names	DMBT1, GP340
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (Glycoprotein 340) (Gp-340) (Surfactant pulmonary-associated D-binding protein).

DMBT1_MOUSE
θ value	θ > 10 (rank : 206)	NC score	0.145771 (rank : 169)
Query Neighborhood Hits	162	Target Neighborhood Hits	134	Shared Neighborhood Hits	13
SwissProt Accessions	Q60997, Q80YC6, Q9JMJ9	Gene names	Dmbt1, Crpd
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (CRP-ductin) (Vomeroglandin).

EGFL7_HUMAN
θ value	θ > 10 (rank : 207)	NC score	0.216728 (rank : 53)
Query Neighborhood Hits	162	Target Neighborhood Hits	325	Shared Neighborhood Hits	118
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

EGFL7_MOUSE
θ value	θ > 10 (rank : 208)	NC score	0.196614 (rank : 81)
Query Neighborhood Hits	162	Target Neighborhood Hits	287	Shared Neighborhood Hits	116
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

EGFL8_HUMAN
θ value	θ > 10 (rank : 209)	NC score	0.196745 (rank : 80)
Query Neighborhood Hits	162	Target Neighborhood Hits	270	Shared Neighborhood Hits	116
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

EGFL8_MOUSE
θ value	θ > 10 (rank : 210)	NC score	0.202270 (rank : 69)
Query Neighborhood Hits	162	Target Neighborhood Hits	266	Shared Neighborhood Hits	118
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

ELTD1_HUMAN
θ value	θ > 10 (rank : 211)	NC score	0.104210 (rank : 259)
Query Neighborhood Hits	162	Target Neighborhood Hits	269	Shared Neighborhood Hits	105
SwissProt Accessions	Q9HBW9	Gene names	ELTD1, ETL
Domain Architecture
Description	EGF, latrophilin and seven transmembrane domain-containing protein 1 precursor (EGF-TM7-latrophilin-related protein) (ETL protein).

ELTD1_MOUSE
θ value	θ > 10 (rank : 212)	NC score	0.129469 (rank : 207)
Query Neighborhood Hits	162	Target Neighborhood Hits	288	Shared Neighborhood Hits	110
SwissProt Accessions	Q923X1, Q91W44	Gene names	Eltd1
Domain Architecture
Description	EGF, latrophilin seven transmembrane domain-containing protein 1 precursor.

EMR3_HUMAN
θ value	θ > 10 (rank : 213)	NC score	0.082911 (rank : 320)
Query Neighborhood Hits	162	Target Neighborhood Hits	245	Shared Neighborhood Hits	90
SwissProt Accessions	Q9BY15	Gene names	EMR3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 3 precursor (EGF-like module-containing mucin-like receptor EMR3).

EMR4_MOUSE
θ value	θ > 10 (rank : 214)	NC score	0.059436 (rank : 407)
Query Neighborhood Hits	162	Target Neighborhood Hits	191	Shared Neighborhood Hits	68
SwissProt Accessions	Q91ZE5, Q3U1I7, Q8BYX0, Q8VIM3	Gene names	Emr4
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 4 precursor (EGF-like module-containing mucin-like receptor EMR4) (F4/80-like-receptor) (Seven-span membrane protein FIRE).

FA7_HUMAN
θ value	θ > 10 (rank : 215)	NC score	0.104902 (rank : 256)
Query Neighborhood Hits	162	Target Neighborhood Hits	404	Shared Neighborhood Hits	129
SwissProt Accessions	P08709, Q14339, Q5JVF2	Gene names	F7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) (SPCA) (Proconvertin) (Eptacog alfa) [Contains: Factor VII light chain; Factor VII heavy chain].

FBLN1_HUMAN
θ value	θ > 10 (rank : 216)	NC score	0.185284 (rank : 97)
Query Neighborhood Hits	162	Target Neighborhood Hits	324	Shared Neighborhood Hits	111
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

FBLN1_MOUSE
θ value	θ > 10 (rank : 217)	NC score	0.183914 (rank : 101)
Query Neighborhood Hits	162	Target Neighborhood Hits	329	Shared Neighborhood Hits	109
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

FBLN2_MOUSE
θ value	θ > 10 (rank : 218)	NC score	0.188334 (rank : 90)
Query Neighborhood Hits	162	Target Neighborhood Hits	505	Shared Neighborhood Hits	115
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

FBLN4_HUMAN
θ value	θ > 10 (rank : 219)	NC score	0.186705 (rank : 93)
Query Neighborhood Hits	162	Target Neighborhood Hits	278	Shared Neighborhood Hits	113
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

FBLN4_MOUSE
θ value	θ > 10 (rank : 220)	NC score	0.184686 (rank : 98)
Query Neighborhood Hits	162	Target Neighborhood Hits	270	Shared Neighborhood Hits	112
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

FBLN5_MOUSE
θ value	θ > 10 (rank : 221)	NC score	0.192927 (rank : 87)
Query Neighborhood Hits	162	Target Neighborhood Hits	317	Shared Neighborhood Hits	113
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

FRAS1_HUMAN
θ value	θ > 10 (rank : 222)	NC score	0.056930 (rank : 419)
Query Neighborhood Hits	162	Target Neighborhood Hits	759	Shared Neighborhood Hits	85
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

FRAS1_MOUSE
θ value	θ > 10 (rank : 223)	NC score	0.055020 (rank : 421)
Query Neighborhood Hits	162	Target Neighborhood Hits	747	Shared Neighborhood Hits	82
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

GAS6_HUMAN
θ value	θ > 10 (rank : 224)	NC score	0.199351 (rank : 77)
Query Neighborhood Hits	162	Target Neighborhood Hits	348	Shared Neighborhood Hits	121
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

GP126_HUMAN
θ value	θ > 10 (rank : 225)	NC score	0.111383 (rank : 243)
Query Neighborhood Hits	162	Target Neighborhood Hits	187	Shared Neighborhood Hits	23
SwissProt Accessions	Q86SQ4, Q6MZU7, Q8NC14, Q96JW0	Gene names	GPR126
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 126 precursor.

GRN_HUMAN
θ value	θ > 10 (rank : 226)	NC score	0.095746 (rank : 284)
Query Neighborhood Hits	162	Target Neighborhood Hits	268	Shared Neighborhood Hits	73
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

GRN_MOUSE
θ value	θ > 10 (rank : 227)	NC score	0.098556 (rank : 274)
Query Neighborhood Hits	162	Target Neighborhood Hits	248	Shared Neighborhood Hits	71
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

HHIP_HUMAN
θ value	θ > 10 (rank : 228)	NC score	0.112888 (rank : 241)
Query Neighborhood Hits	162	Target Neighborhood Hits	249	Shared Neighborhood Hits	76
SwissProt Accessions	Q96QV1, Q6PK09, Q8NCI7, Q9BXK3, Q9H1J4, Q9H7E7	Gene names	HHIP, HIP
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

HHIP_MOUSE
θ value	θ > 10 (rank : 229)	NC score	0.110727 (rank : 246)
Query Neighborhood Hits	162	Target Neighborhood Hits	219	Shared Neighborhood Hits	76
SwissProt Accessions	Q7TN16, Q8C0B0, Q9WU59	Gene names	Hhip, Hip
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

HMCN1_HUMAN
θ value	θ > 10 (rank : 230)	NC score	0.127147 (rank : 211)
Query Neighborhood Hits	162	Target Neighborhood Hits	983	Shared Neighborhood Hits	119
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

ITB1_HUMAN
θ value	θ > 10 (rank : 231)	NC score	0.070628 (rank : 380)
Query Neighborhood Hits	162	Target Neighborhood Hits	298	Shared Neighborhood Hits	82
SwissProt Accessions	P05556, P78466, P78467, Q13089, Q13090, Q13091, Q13212, Q14622, Q14647	Gene names	ITGB1, FNRB
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

ITB1_MOUSE
θ value	θ > 10 (rank : 232)	NC score	0.073128 (rank : 368)
Query Neighborhood Hits	162	Target Neighborhood Hits	283	Shared Neighborhood Hits	83
SwissProt Accessions	P09055	Gene names	Itgb1
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

ITB2_HUMAN
θ value	θ > 10 (rank : 233)	NC score	0.068414 (rank : 389)
Query Neighborhood Hits	162	Target Neighborhood Hits	282	Shared Neighborhood Hits	87
SwissProt Accessions	P05107, Q16418	Gene names	ITGB2, CD18
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

ITB2_MOUSE
θ value	θ > 10 (rank : 234)	NC score	0.068894 (rank : 388)
Query Neighborhood Hits	162	Target Neighborhood Hits	326	Shared Neighborhood Hits	94
SwissProt Accessions	P11835, Q64482	Gene names	Itgb2
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/P150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

ITB3_HUMAN
θ value	θ > 10 (rank : 235)	NC score	0.071323 (rank : 376)
Query Neighborhood Hits	162	Target Neighborhood Hits	325	Shared Neighborhood Hits	94
SwissProt Accessions	P05106, O15495, Q13413, Q14648, Q16499	Gene names	ITGB3, GP3A
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

ITB3_MOUSE
θ value	θ > 10 (rank : 236)	NC score	0.066183 (rank : 394)
Query Neighborhood Hits	162	Target Neighborhood Hits	319	Shared Neighborhood Hits	86
SwissProt Accessions	O54890	Gene names	Itgb3
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

ITB4_HUMAN
θ value	θ > 10 (rank : 237)	NC score	0.074524 (rank : 359)
Query Neighborhood Hits	162	Target Neighborhood Hits	458	Shared Neighborhood Hits	95
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

ITB5_HUMAN
θ value	θ > 10 (rank : 238)	NC score	0.075191 (rank : 357)
Query Neighborhood Hits	162	Target Neighborhood Hits	310	Shared Neighborhood Hits	96
SwissProt Accessions	P18084	Gene names	ITGB5
Domain Architecture
Description	Integrin beta-5 precursor.

ITB5_MOUSE
θ value	θ > 10 (rank : 239)	NC score	0.078536 (rank : 337)
Query Neighborhood Hits	162	Target Neighborhood Hits	329	Shared Neighborhood Hits	98
SwissProt Accessions	O70309, O70308, O88347	Gene names	Itgb5
Domain Architecture
Description	Integrin beta-5 precursor.

ITB6_HUMAN
θ value	θ > 10 (rank : 240)	NC score	0.079841 (rank : 333)
Query Neighborhood Hits	162	Target Neighborhood Hits	318	Shared Neighborhood Hits	87
SwissProt Accessions	P18564, Q16500	Gene names	ITGB6
Domain Architecture
Description	Integrin beta-6 precursor.

ITB6_MOUSE
θ value	θ > 10 (rank : 241)	NC score	0.082874 (rank : 321)
Query Neighborhood Hits	162	Target Neighborhood Hits	341	Shared Neighborhood Hits	96
SwissProt Accessions	Q9Z0T9	Gene names	Itgb6
Domain Architecture
Description	Integrin beta-6 precursor.

ITB7_HUMAN
θ value	θ > 10 (rank : 242)	NC score	0.079917 (rank : 332)
Query Neighborhood Hits	162	Target Neighborhood Hits	290	Shared Neighborhood Hits	95
SwissProt Accessions	P26010	Gene names	ITGB7
Domain Architecture
Description	Integrin beta-7 precursor.

ITB7_MOUSE
θ value	θ > 10 (rank : 243)	NC score	0.074456 (rank : 360)
Query Neighborhood Hits	162	Target Neighborhood Hits	277	Shared Neighborhood Hits	86
SwissProt Accessions	P26011, Q3U2M1, Q64656	Gene names	Itgb7
Domain Architecture
Description	Integrin beta-7 precursor (Integrin beta-P) (M290 IEL antigen).

ITB8_HUMAN
θ value	θ > 10 (rank : 244)	NC score	0.053870 (rank : 424)
Query Neighborhood Hits	162	Target Neighborhood Hits	280	Shared Neighborhood Hits	78
SwissProt Accessions	P26012	Gene names	ITGB8
Domain Architecture
Description	Integrin beta-8 precursor.

KR101_HUMAN
θ value	θ > 10 (rank : 245)	NC score	0.095690 (rank : 285)
Query Neighborhood Hits	162	Target Neighborhood Hits	261	Shared Neighborhood Hits	62
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

KR102_HUMAN
θ value	θ > 10 (rank : 246)	NC score	0.087177 (rank : 308)
Query Neighborhood Hits	162	Target Neighborhood Hits	264	Shared Neighborhood Hits	61
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

KR103_HUMAN
θ value	θ > 10 (rank : 247)	NC score	0.057902 (rank : 413)
Query Neighborhood Hits	162	Target Neighborhood Hits	212	Shared Neighborhood Hits	51
SwissProt Accessions	P60369, Q70LJ4	Gene names	KRTAP10-3, KAP10.3, KAP18-3, KRTAP10.3, KRTAP18-3, KRTAP18.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-3 (Keratin-associated protein 10.3) (High sulfur keratin-associated protein 10.3) (Keratin-associated protein 18-3) (Keratin-associated protein 18.3).

KR104_HUMAN
θ value	θ > 10 (rank : 248)	NC score	0.112414 (rank : 242)
Query Neighborhood Hits	162	Target Neighborhood Hits	313	Shared Neighborhood Hits	77
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

KR105_HUMAN
θ value	θ > 10 (rank : 249)	NC score	0.080647 (rank : 330)
Query Neighborhood Hits	162	Target Neighborhood Hits	271	Shared Neighborhood Hits	66
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

KR106_HUMAN
θ value	θ > 10 (rank : 250)	NC score	0.113326 (rank : 238)
Query Neighborhood Hits	162	Target Neighborhood Hits	347	Shared Neighborhood Hits	78
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

KR107_HUMAN
θ value	θ > 10 (rank : 251)	NC score	0.114512 (rank : 237)
Query Neighborhood Hits	162	Target Neighborhood Hits	330	Shared Neighborhood Hits	79
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

KR108_HUMAN
θ value	θ > 10 (rank : 252)	NC score	0.078378 (rank : 338)
Query Neighborhood Hits	162	Target Neighborhood Hits	226	Shared Neighborhood Hits	57
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

KR109_HUMAN
θ value	θ > 10 (rank : 253)	NC score	0.084304 (rank : 318)
Query Neighborhood Hits	162	Target Neighborhood Hits	226	Shared Neighborhood Hits	64
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

KR10A_HUMAN
θ value	θ > 10 (rank : 254)	NC score	0.057430 (rank : 416)
Query Neighborhood Hits	162	Target Neighborhood Hits	232	Shared Neighborhood Hits	53
SwissProt Accessions	P60014	Gene names	KRTAP10-10, KAP10.10, KAP18-10, KRTAP10.10, KRTAP18-1, KRTAP18.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-10 (Keratin-associated protein 10.10) (High sulfur keratin-associated protein 10.10) (Keratin-associated protein 18-10) (Keratin-associated protein 18.10).

KR10B_HUMAN
θ value	θ > 10 (rank : 255)	NC score	0.069796 (rank : 383)
Query Neighborhood Hits	162	Target Neighborhood Hits	269	Shared Neighborhood Hits	59
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

KR10C_HUMAN
θ value	θ > 10 (rank : 256)	NC score	0.075656 (rank : 354)
Query Neighborhood Hits	162	Target Neighborhood Hits	219	Shared Neighborhood Hits	57
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

KR171_HUMAN
θ value	θ > 10 (rank : 257)	NC score	0.073867 (rank : 362)
Query Neighborhood Hits	162	Target Neighborhood Hits	144	Shared Neighborhood Hits	40
SwissProt Accessions	Q9BYP8	Gene names	KRTAP17-1, KAP17.1, KRTAP16.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 17-1 (Keratin-associated protein 16.1).

KR412_HUMAN
θ value	θ > 10 (rank : 258)	NC score	0.054972 (rank : 422)
Query Neighborhood Hits	162	Target Neighborhood Hits	178	Shared Neighborhood Hits	32
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

KR414_HUMAN
θ value	θ > 10 (rank : 259)	NC score	0.061994 (rank : 401)
Query Neighborhood Hits	162	Target Neighborhood Hits	199	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

KR511_HUMAN
θ value	θ > 10 (rank : 260)	NC score	0.059867 (rank : 406)
Query Neighborhood Hits	162	Target Neighborhood Hits	231	Shared Neighborhood Hits	43
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

KRA11_HUMAN
θ value	θ > 10 (rank : 261)	NC score	0.054922 (rank : 423)
Query Neighborhood Hits	162	Target Neighborhood Hits	155	Shared Neighborhood Hits	36
SwissProt Accessions	Q07627, Q96S60, Q96S67	Gene names	KRTAP1-1, B2A, KAP1.1, KAP1.6, KAP1.7, KRTAP1.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-1 (Keratin-associated protein 1.1) (High sulfur keratin-associated protein 1.1) (Keratin-associated protein 1.6) (Keratin-associated protein 1.7).

KRA13_HUMAN
θ value	θ > 10 (rank : 262)	NC score	0.064984 (rank : 396)
Query Neighborhood Hits	162	Target Neighborhood Hits	144	Shared Neighborhood Hits	37
SwissProt Accessions	Q8IUG1, Q07628, Q8IUG0, Q9BYS2	Gene names	KRTAP1-3, B2B, KAP1.2, KAP1.3, KAP1.8, KAP1.9, KRATP1.9, KRTAP1.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-3 (Keratin-associated protein 1.8) (Keratin-associated protein 1.9).

KRA15_HUMAN
θ value	θ > 10 (rank : 263)	NC score	0.057568 (rank : 415)
Query Neighborhood Hits	162	Target Neighborhood Hits	126	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BYS1, Q52LP6	Gene names	KRTAP1-5, KAP1.5, KRTAP1.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-5 (Keratin-associated protein 1.5) (High sulfur keratin-associated protein 1.5).

KRA44_HUMAN
θ value	θ > 10 (rank : 264)	NC score	0.070267 (rank : 381)
Query Neighborhood Hits	162	Target Neighborhood Hits	162	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BYR3	Gene names	KRTAP4-4, KAP4.4, KRTAP4.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-4 (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.4).

KRA45_HUMAN
θ value	θ > 10 (rank : 265)	NC score	0.059926 (rank : 405)
Query Neighborhood Hits	162	Target Neighborhood Hits	194	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BYR2	Gene names	KRTAP4-5, KAP4.5, KRTAP4.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-5 (Keratin-associated protein 4.5) (Ultrahigh sulfur keratin-associated protein 4.5).

KRA47_HUMAN
θ value	θ > 10 (rank : 266)	NC score	0.053209 (rank : 428)
Query Neighborhood Hits	162	Target Neighborhood Hits	204	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BYR0	Gene names	KRTAP4-7, KAP4.7, KRTAP4.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-7 (Keratin-associated protein 4.7) (Ultrahigh sulfur keratin-associated protein 4.7).

KRA51_HUMAN
θ value	θ > 10 (rank : 267)	NC score	0.096608 (rank : 280)
Query Neighborhood Hits	162	Target Neighborhood Hits	288	Shared Neighborhood Hits	64
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

KRA52_HUMAN
θ value	θ > 10 (rank : 268)	NC score	0.052621 (rank : 432)
Query Neighborhood Hits	162	Target Neighborhood Hits	236	Shared Neighborhood Hits	43
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

KRA53_HUMAN
θ value	θ > 10 (rank : 269)	NC score	0.097602 (rank : 276)
Query Neighborhood Hits	162	Target Neighborhood Hits	331	Shared Neighborhood Hits	74
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

KRA54_HUMAN
θ value	θ > 10 (rank : 270)	NC score	0.070940 (rank : 378)
Query Neighborhood Hits	162	Target Neighborhood Hits	270	Shared Neighborhood Hits	53
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

KRA55_HUMAN
θ value	θ > 10 (rank : 271)	NC score	0.074667 (rank : 358)
Query Neighborhood Hits	162	Target Neighborhood Hits	257	Shared Neighborhood Hits	55
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

KRA57_HUMAN
θ value	θ > 10 (rank : 272)	NC score	0.077245 (rank : 345)
Query Neighborhood Hits	162	Target Neighborhood Hits	269	Shared Neighborhood Hits	54
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

KRA58_HUMAN
θ value	θ > 10 (rank : 273)	NC score	0.091903 (rank : 294)
Query Neighborhood Hits	162	Target Neighborhood Hits	324	Shared Neighborhood Hits	64
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

KRA59_HUMAN
θ value	θ > 10 (rank : 274)	NC score	0.081898 (rank : 325)
Query Neighborhood Hits	162	Target Neighborhood Hits	310	Shared Neighborhood Hits	54
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

KRA92_HUMAN
θ value	θ > 10 (rank : 275)	NC score	0.057840 (rank : 414)
Query Neighborhood Hits	162	Target Neighborhood Hits	198	Shared Neighborhood Hits	37
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

KRA93_HUMAN
θ value	θ > 10 (rank : 276)	NC score	0.070807 (rank : 379)
Query Neighborhood Hits	162	Target Neighborhood Hits	203	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

KRA94_HUMAN
θ value	θ > 10 (rank : 277)	NC score	0.071898 (rank : 374)
Query Neighborhood Hits	162	Target Neighborhood Hits	204	Shared Neighborhood Hits	43
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

KRA98_HUMAN
θ value	θ > 10 (rank : 278)	NC score	0.068969 (rank : 387)
Query Neighborhood Hits	162	Target Neighborhood Hits	185	Shared Neighborhood Hits	42
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

KRA99_HUMAN
θ value	θ > 10 (rank : 279)	NC score	0.058813 (rank : 410)
Query Neighborhood Hits	162	Target Neighborhood Hits	173	Shared Neighborhood Hits	43
SwissProt Accessions	Q9BYP9	Gene names	KRTAP9-9, KAP9.9, KRTAP9.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-9 (Keratin-associated protein 9.9) (Ultrahigh sulfur keratin-associated protein 9.9).

KREM1_HUMAN
θ value	θ > 10 (rank : 280)	NC score	0.101345 (rank : 267)
Query Neighborhood Hits	162	Target Neighborhood Hits	90	Shared Neighborhood Hits	18
SwissProt Accessions	Q96MU8, Q5TIB9, Q6P3X6, Q9BY70, Q9UGS5, Q9UGU1	Gene names	KREMEN1, KREMEN, KRM1
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

KREM1_MOUSE
θ value	θ > 10 (rank : 281)	NC score	0.091631 (rank : 295)
Query Neighborhood Hits	162	Target Neighborhood Hits	92	Shared Neighborhood Hits	19
SwissProt Accessions	Q99N43	Gene names	Kremen1, Kremen
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

KREM2_HUMAN
θ value	θ > 10 (rank : 282)	NC score	0.111294 (rank : 244)
Query Neighborhood Hits	162	Target Neighborhood Hits	93	Shared Neighborhood Hits	19
SwissProt Accessions	Q8NCW0, Q8N2J4, Q8NCW1, Q96GL8, Q9BTP9	Gene names	KREMEN2, KRM2
Domain Architecture
Description	Kremen protein 2 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 2) (Dickkopf receptor 2).

KREM2_MOUSE
θ value	θ > 10 (rank : 283)	NC score	0.105892 (rank : 253)
Query Neighborhood Hits	162	Target Neighborhood Hits	90	Shared Neighborhood Hits	18
SwissProt Accessions	Q8K1S7	Gene names	Kremen2
Domain Architecture
Description	Kremen protein 2 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 2) (Dickkopf receptor 2).

LAMA1_HUMAN
θ value	θ > 10 (rank : 284)	NC score	0.088536 (rank : 304)
Query Neighborhood Hits	162	Target Neighborhood Hits	804	Shared Neighborhood Hits	106
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMA1_MOUSE
θ value	θ > 10 (rank : 285)	NC score	0.089247 (rank : 302)
Query Neighborhood Hits	162	Target Neighborhood Hits	838	Shared Neighborhood Hits	114
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMA2_HUMAN
θ value	θ > 10 (rank : 286)	NC score	0.082208 (rank : 323)
Query Neighborhood Hits	162	Target Neighborhood Hits	1092	Shared Neighborhood Hits	112
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMA2_MOUSE
θ value	θ > 10 (rank : 287)	NC score	0.078032 (rank : 339)
Query Neighborhood Hits	162	Target Neighborhood Hits	1198	Shared Neighborhood Hits	112
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMA3_HUMAN
θ value	θ > 10 (rank : 288)	NC score	0.067221 (rank : 391)
Query Neighborhood Hits	162	Target Neighborhood Hits	760	Shared Neighborhood Hits	100
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

LAMA3_MOUSE
θ value	θ > 10 (rank : 289)	NC score	0.072134 (rank : 373)
Query Neighborhood Hits	162	Target Neighborhood Hits	859	Shared Neighborhood Hits	107
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

LAMA4_HUMAN
θ value	θ > 10 (rank : 290)	NC score	0.062518 (rank : 400)
Query Neighborhood Hits	162	Target Neighborhood Hits	708	Shared Neighborhood Hits	96
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

LAMA4_MOUSE
θ value	θ > 10 (rank : 291)	NC score	0.063628 (rank : 399)
Query Neighborhood Hits	162	Target Neighborhood Hits	584	Shared Neighborhood Hits	93
SwissProt Accessions	P97927, O88785, P70409	Gene names	Lama4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

LAMA5_HUMAN
θ value	θ > 10 (rank : 292)	NC score	0.094195 (rank : 288)
Query Neighborhood Hits	162	Target Neighborhood Hits	976	Shared Neighborhood Hits	114
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LAMA5_MOUSE
θ value	θ > 10 (rank : 293)	NC score	0.098646 (rank : 272)
Query Neighborhood Hits	162	Target Neighborhood Hits	828	Shared Neighborhood Hits	120
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

LAMB1_HUMAN
θ value	θ > 10 (rank : 294)	NC score	0.084326 (rank : 317)
Query Neighborhood Hits	162	Target Neighborhood Hits	1018	Shared Neighborhood Hits	108
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

LAMB1_MOUSE
θ value	θ > 10 (rank : 295)	NC score	0.090781 (rank : 297)
Query Neighborhood Hits	162	Target Neighborhood Hits	919	Shared Neighborhood Hits	112
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

LAMB2_HUMAN
θ value	θ > 10 (rank : 296)	NC score	0.092850 (rank : 290)
Query Neighborhood Hits	162	Target Neighborhood Hits	692	Shared Neighborhood Hits	109
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

LAMB2_MOUSE
θ value	θ > 10 (rank : 297)	NC score	0.090133 (rank : 299)
Query Neighborhood Hits	162	Target Neighborhood Hits	722	Shared Neighborhood Hits	104
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

LAMB3_HUMAN
θ value	θ > 10 (rank : 298)	NC score	0.069403 (rank : 384)
Query Neighborhood Hits	162	Target Neighborhood Hits	461	Shared Neighborhood Hits	77
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

LAMB3_MOUSE
θ value	θ > 10 (rank : 299)	NC score	0.077580 (rank : 343)
Query Neighborhood Hits	162	Target Neighborhood Hits	444	Shared Neighborhood Hits	85
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

LAMC1_HUMAN
θ value	θ > 10 (rank : 300)	NC score	0.077994 (rank : 340)
Query Neighborhood Hits	162	Target Neighborhood Hits	922	Shared Neighborhood Hits	105
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LAMC1_MOUSE
θ value	θ > 10 (rank : 301)	NC score	0.079698 (rank : 334)
Query Neighborhood Hits	162	Target Neighborhood Hits	856	Shared Neighborhood Hits	103
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

LAMC2_HUMAN
θ value	θ > 10 (rank : 302)	NC score	0.086562 (rank : 310)
Query Neighborhood Hits	162	Target Neighborhood Hits	715	Shared Neighborhood Hits	97
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

LAMC2_MOUSE
θ value	θ > 10 (rank : 303)	NC score	0.089681 (rank : 301)
Query Neighborhood Hits	162	Target Neighborhood Hits	614	Shared Neighborhood Hits	102
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

LAMC3_HUMAN
θ value	θ > 10 (rank : 304)	NC score	0.087271 (rank : 306)
Query Neighborhood Hits	162	Target Neighborhood Hits	588	Shared Neighborhood Hits	106
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LAMC3_MOUSE
θ value	θ > 10 (rank : 305)	NC score	0.088849 (rank : 303)
Query Neighborhood Hits	162	Target Neighborhood Hits	624	Shared Neighborhood Hits	105
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LCE1B_HUMAN
θ value	θ > 10 (rank : 306)	NC score	0.066889 (rank : 393)
Query Neighborhood Hits	162	Target Neighborhood Hits	58	Shared Neighborhood Hits	17
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

LCE1C_HUMAN
θ value	θ > 10 (rank : 307)	NC score	0.059222 (rank : 408)
Query Neighborhood Hits	162	Target Neighborhood Hits	65	Shared Neighborhood Hits	14
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

LCE1E_HUMAN
θ value	θ > 10 (rank : 308)	NC score	0.052681 (rank : 431)
Query Neighborhood Hits	162	Target Neighborhood Hits	53	Shared Neighborhood Hits	10
SwissProt Accessions	Q5T753	Gene names	LCE1E, LEP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1E (Late envelope protein 5).

LDLR_HUMAN
θ value	θ > 10 (rank : 309)	NC score	0.144077 (rank : 176)
Query Neighborhood Hits	162	Target Neighborhood Hits	375	Shared Neighborhood Hits	108
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LDLR_MOUSE
θ value	θ > 10 (rank : 310)	NC score	0.136246 (rank : 195)
Query Neighborhood Hits	162	Target Neighborhood Hits	382	Shared Neighborhood Hits	104
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LRP10_HUMAN
θ value	θ > 10 (rank : 311)	NC score	0.053696 (rank : 425)
Query Neighborhood Hits	162	Target Neighborhood Hits	197	Shared Neighborhood Hits	28
SwissProt Accessions	Q7Z4F1, O95882, Q86T02, Q8NCZ4, Q9HC42, Q9UG33	Gene names	LRP10
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

LRP10_MOUSE
θ value	θ > 10 (rank : 312)	NC score	0.061261 (rank : 402)
Query Neighborhood Hits	162	Target Neighborhood Hits	169	Shared Neighborhood Hits	31
SwissProt Accessions	Q7TQH7, Q7TS95, Q921T0, Q9EPE8	Gene names	Lrp10, Lrp9
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

LRP12_HUMAN
θ value	θ > 10 (rank : 313)	NC score	0.143878 (rank : 178)
Query Neighborhood Hits	162	Target Neighborhood Hits	205	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

LRP12_MOUSE
θ value	θ > 10 (rank : 314)	NC score	0.144440 (rank : 174)
Query Neighborhood Hits	162	Target Neighborhood Hits	180	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BUJ9, Q8BWM9	Gene names	Lrp12
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor.

LRP1_HUMAN
θ value	θ > 10 (rank : 315)	NC score	0.161494 (rank : 148)
Query Neighborhood Hits	162	Target Neighborhood Hits	617	Shared Neighborhood Hits	128
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

LRP2_HUMAN
θ value	θ > 10 (rank : 316)	NC score	0.144130 (rank : 175)
Query Neighborhood Hits	162	Target Neighborhood Hits	573	Shared Neighborhood Hits	124
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

LRP3_HUMAN
θ value	θ > 10 (rank : 317)	NC score	0.119909 (rank : 229)
Query Neighborhood Hits	162	Target Neighborhood Hits	280	Shared Neighborhood Hits	53
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

LRP4_HUMAN
θ value	θ > 10 (rank : 318)	NC score	0.126393 (rank : 213)
Query Neighborhood Hits	162	Target Neighborhood Hits	355	Shared Neighborhood Hits	102
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

LRP4_MOUSE
θ value	θ > 10 (rank : 319)	NC score	0.127483 (rank : 210)
Query Neighborhood Hits	162	Target Neighborhood Hits	351	Shared Neighborhood Hits	100
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

LRP5_HUMAN
θ value	θ > 10 (rank : 320)	NC score	0.076193 (rank : 350)
Query Neighborhood Hits	162	Target Neighborhood Hits	224	Shared Neighborhood Hits	65
SwissProt Accessions	O75197, Q96TD6, Q9UP66	Gene names	LRP5, LRP7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor.

LRP5_MOUSE
θ value	θ > 10 (rank : 321)	NC score	0.073963 (rank : 361)
Query Neighborhood Hits	162	Target Neighborhood Hits	236	Shared Neighborhood Hits	69
SwissProt Accessions	Q91VN0, O88883, Q9R208	Gene names	Lrp5, Lrp7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor (LRP7) (Lr3).

LRP6_HUMAN
θ value	θ > 10 (rank : 322)	NC score	0.073371 (rank : 364)
Query Neighborhood Hits	162	Target Neighborhood Hits	235	Shared Neighborhood Hits	70
SwissProt Accessions	O75581	Gene names	LRP6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

LRP6_MOUSE
θ value	θ > 10 (rank : 323)	NC score	0.072618 (rank : 372)
Query Neighborhood Hits	162	Target Neighborhood Hits	232	Shared Neighborhood Hits	70
SwissProt Accessions	O88572	Gene names	Lrp6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

LTBP4_MOUSE
θ value	θ > 10 (rank : 324)	NC score	0.202780 (rank : 67)
Query Neighborhood Hits	162	Target Neighborhood Hits	607	Shared Neighborhood Hits	121
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

LYAM1_HUMAN
θ value	θ > 10 (rank : 325)	NC score	0.071632 (rank : 375)
Query Neighborhood Hits	162	Target Neighborhood Hits	315	Shared Neighborhood Hits	101
SwissProt Accessions	P14151, P15023	Gene names	SELL, LNHR, LYAM1
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte surface antigen Leu-8) (TQ1) (gp90-MEL) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

LYAM1_MOUSE
θ value	θ > 10 (rank : 326)	NC score	0.075454 (rank : 356)
Query Neighborhood Hits	162	Target Neighborhood Hits	332	Shared Neighborhood Hits	102
SwissProt Accessions	P18337	Gene names	Sell, Lnhr, Ly-22
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Lymphocyte antigen 22) (Ly-22) (Lymphocyte surface MEL-14 antigen) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

LYAM2_HUMAN
θ value	θ > 10 (rank : 327)	NC score	0.091474 (rank : 296)
Query Neighborhood Hits	162	Target Neighborhood Hits	394	Shared Neighborhood Hits	117
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

LYAM2_MOUSE
θ value	θ > 10 (rank : 328)	NC score	0.092454 (rank : 292)
Query Neighborhood Hits	162	Target Neighborhood Hits	420	Shared Neighborhood Hits	114
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

LYAM3_HUMAN
θ value	θ > 10 (rank : 329)	NC score	0.087625 (rank : 305)
Query Neighborhood Hits	162	Target Neighborhood Hits	378	Shared Neighborhood Hits	114
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

MASP1_HUMAN
θ value	θ > 10 (rank : 330)	NC score	0.122708 (rank : 221)
Query Neighborhood Hits	162	Target Neighborhood Hits	369	Shared Neighborhood Hits	77
SwissProt Accessions	P48740, O95570, Q9UF09	Gene names	MASP1, CRARF, CRARF1, PRSS5
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) (Mannose-binding protein- associated serine protease) (MASP-1) [Contains: Complement-activating component of Ra-reactive factor heavy chain; Complement-activating component of Ra-reactive factor light chain].

MASP1_MOUSE
θ value	θ > 10 (rank : 331)	NC score	0.120510 (rank : 228)
Query Neighborhood Hits	162	Target Neighborhood Hits	364	Shared Neighborhood Hits	78
SwissProt Accessions	P98064	Gene names	Masp1, Crarf
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) [Contains: Complement- activating component of Ra-reactive factor heavy chain; Complement- activating component of Ra-reactive factor light chain].

MASP2_HUMAN
θ value	θ > 10 (rank : 332)	NC score	0.121909 (rank : 225)
Query Neighborhood Hits	162	Target Neighborhood Hits	364	Shared Neighborhood Hits	77
SwissProt Accessions	O00187, O75754, Q5TEQ5, Q5TER0, Q96QG4, Q9BZH0, Q9H498, Q9H499, Q9UBP3, Q9ULC7, Q9UMV3, Q9Y270	Gene names	MASP2
Domain Architecture
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

MASP2_MOUSE
θ value	θ > 10 (rank : 333)	NC score	0.122236 (rank : 223)
Query Neighborhood Hits	162	Target Neighborhood Hits	382	Shared Neighborhood Hits	84
SwissProt Accessions	Q91WP0, Q9QXA4, Q9QXD2, Q9QXD5, Q9Z338	Gene names	Masp2
Domain Architecture	No domain graphic available
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

MATN1_HUMAN
θ value	θ > 10 (rank : 334)	NC score	0.077401 (rank : 344)
Query Neighborhood Hits	162	Target Neighborhood Hits	191	Shared Neighborhood Hits	70
SwissProt Accessions	P21941	Gene names	MATN1, CMP, CRTM
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

MATN1_MOUSE
θ value	θ > 10 (rank : 335)	NC score	0.077899 (rank : 341)
Query Neighborhood Hits	162	Target Neighborhood Hits	186	Shared Neighborhood Hits	68
SwissProt Accessions	P51942	Gene names	Matn1, Cmp, Crtm
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

MATN3_HUMAN
θ value	θ > 10 (rank : 336)	NC score	0.140169 (rank : 185)
Query Neighborhood Hits	162	Target Neighborhood Hits	268	Shared Neighborhood Hits	97
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

MATN3_MOUSE
θ value	θ > 10 (rank : 337)	NC score	0.140423 (rank : 183)
Query Neighborhood Hits	162	Target Neighborhood Hits	261	Shared Neighborhood Hits	95
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

MATN4_HUMAN
θ value	θ > 10 (rank : 338)	NC score	0.151370 (rank : 161)
Query Neighborhood Hits	162	Target Neighborhood Hits	287	Shared Neighborhood Hits	103
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

MATN4_MOUSE
θ value	θ > 10 (rank : 339)	NC score	0.136629 (rank : 193)
Query Neighborhood Hits	162	Target Neighborhood Hits	277	Shared Neighborhood Hits	97
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

MEGF6_HUMAN
θ value	θ > 10 (rank : 340)	NC score	0.197378 (rank : 79)
Query Neighborhood Hits	162	Target Neighborhood Hits	671	Shared Neighborhood Hits	128
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

MEGF8_HUMAN
θ value	θ > 10 (rank : 341)	NC score	0.126186 (rank : 215)
Query Neighborhood Hits	162	Target Neighborhood Hits	528	Shared Neighborhood Hits	115
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MEGF8_MOUSE
θ value	θ > 10 (rank : 342)	NC score	0.125860 (rank : 217)
Query Neighborhood Hits	162	Target Neighborhood Hits	520	Shared Neighborhood Hits	114
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

MEGF9_HUMAN
θ value	θ > 10 (rank : 343)	NC score	0.092701 (rank : 291)
Query Neighborhood Hits	162	Target Neighborhood Hits	557	Shared Neighborhood Hits	96
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MEGF9_MOUSE
θ value	θ > 10 (rank : 344)	NC score	0.085959 (rank : 313)
Query Neighborhood Hits	162	Target Neighborhood Hits	896	Shared Neighborhood Hits	91
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

MFRP_HUMAN
θ value	θ > 10 (rank : 345)	NC score	0.165120 (rank : 138)
Query Neighborhood Hits	162	Target Neighborhood Hits	165	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

MFRP_MOUSE
θ value	θ > 10 (rank : 346)	NC score	0.160471 (rank : 150)
Query Neighborhood Hits	162	Target Neighborhood Hits	166	Shared Neighborhood Hits	20
SwissProt Accessions	Q8K480, Q8BPP4	Gene names	Mfrp
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

MUC5B_HUMAN
θ value	θ > 10 (rank : 347)	NC score	0.051161 (rank : 434)
Query Neighborhood Hits	162	Target Neighborhood Hits	1020	Shared Neighborhood Hits	90
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

NAGPA_HUMAN
θ value	θ > 10 (rank : 348)	NC score	0.104656 (rank : 258)
Query Neighborhood Hits	162	Target Neighborhood Hits	282	Shared Neighborhood Hits	79
SwissProt Accessions	Q9UK23, Q96EJ8	Gene names	NAGPA
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

NAGPA_MOUSE
θ value	θ > 10 (rank : 349)	NC score	0.102482 (rank : 265)
Query Neighborhood Hits	162	Target Neighborhood Hits	308	Shared Neighborhood Hits	91
SwissProt Accessions	Q8BJ48, Q3UUT5, Q8CHQ8, Q9QZE6	Gene names	Nagpa
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

NELL1_HUMAN
θ value	θ > 10 (rank : 350)	NC score	0.175735 (rank : 118)
Query Neighborhood Hits	162	Target Neighborhood Hits	451	Shared Neighborhood Hits	120
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

NELL2_HUMAN
θ value	θ > 10 (rank : 351)	NC score	0.180533 (rank : 110)
Query Neighborhood Hits	162	Target Neighborhood Hits	449	Shared Neighborhood Hits	125
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

NELL2_MOUSE
θ value	θ > 10 (rank : 352)	NC score	0.179103 (rank : 112)
Query Neighborhood Hits	162	Target Neighborhood Hits	436	Shared Neighborhood Hits	123
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

NETO1_HUMAN
θ value	θ > 10 (rank : 353)	NC score	0.168610 (rank : 131)
Query Neighborhood Hits	162	Target Neighborhood Hits	110	Shared Neighborhood Hits	22
SwissProt Accessions	Q8TDF5, Q86W85, Q8ND78, Q8TDF4	Gene names	NETO1, BTCL1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

NETO1_MOUSE
θ value	θ > 10 (rank : 354)	NC score	0.168842 (rank : 130)
Query Neighborhood Hits	162	Target Neighborhood Hits	109	Shared Neighborhood Hits	22
SwissProt Accessions	Q8R4I7, Q80X39, Q8C4S3, Q8CCM2	Gene names	Neto1, Btcl1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

NETO2_HUMAN
θ value	θ > 10 (rank : 355)	NC score	0.170574 (rank : 125)
Query Neighborhood Hits	162	Target Neighborhood Hits	109	Shared Neighborhood Hits	19
SwissProt Accessions	Q8NC67, Q7Z381, Q8ND51, Q96SP4, Q9NVY8	Gene names	NETO2, BTCL2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

NETO2_MOUSE
θ value	θ > 10 (rank : 356)	NC score	0.170396 (rank : 127)
Query Neighborhood Hits	162	Target Neighborhood Hits	113	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BNJ6, Q5VM49, Q8C4Q8	Gene names	Neto2, Btcl2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

NFX1_HUMAN
θ value	θ > 10 (rank : 357)	NC score	0.053284 (rank : 427)
Query Neighborhood Hits	162	Target Neighborhood Hits	405	Shared Neighborhood Hits	52
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

NRG1_HUMAN
θ value	θ > 10 (rank : 358)	NC score	0.064739 (rank : 397)
Query Neighborhood Hits	162	Target Neighborhood Hits	285	Shared Neighborhood Hits	63
SwissProt Accessions	Q02297, O14667, P98202, Q02298, Q02299, Q07110, Q07111, Q12779, Q12780, Q12781, Q12782, Q12783, Q12784, Q7RTV9, Q7RTW0, Q7RTW1, Q7RTW2, Q8NFN1, Q8NFN2, Q8NFN3, Q9UPE3	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture
Description	Pro-neuregulin-1, membrane-bound isoform precursor (Pro-NRG1) [Contains: Neuregulin-1 (Neu differentiation factor) (Heregulin) (HRG) (Breast cancer cell differentiation factor p45) (Acetylcholine receptor-inducing activity) (ARIA) (Sensory and motor neuron-derived factor) (Glial growth factor)].

NRG2_HUMAN
θ value	θ > 10 (rank : 359)	NC score	0.083093 (rank : 319)
Query Neighborhood Hits	162	Target Neighborhood Hits	419	Shared Neighborhood Hits	67
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

NRG4_HUMAN
θ value	θ > 10 (rank : 360)	NC score	0.075682 (rank : 353)
Query Neighborhood Hits	162	Target Neighborhood Hits	85	Shared Neighborhood Hits	54
SwissProt Accessions	Q8WWG1	Gene names	NRG4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

NRG4_MOUSE
θ value	θ > 10 (rank : 361)	NC score	0.072783 (rank : 370)
Query Neighborhood Hits	162	Target Neighborhood Hits	79	Shared Neighborhood Hits	50
SwissProt Accessions	Q9WTX4	Gene names	Nrg4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

NRP2_MOUSE
θ value	θ > 10 (rank : 362)	NC score	0.209626 (rank : 62)
Query Neighborhood Hits	162	Target Neighborhood Hits	113	Shared Neighborhood Hits	26
SwissProt Accessions	O35375, O35373, O35374, O35376, O35377, O35378	Gene names	Nrp2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

NRX2A_HUMAN
θ value	θ > 10 (rank : 363)	NC score	0.077086 (rank : 346)
Query Neighborhood Hits	162	Target Neighborhood Hits	614	Shared Neighborhood Hits	88
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

NTNG1_HUMAN
θ value	θ > 10 (rank : 364)	NC score	0.081806 (rank : 326)
Query Neighborhood Hits	162	Target Neighborhood Hits	247	Shared Neighborhood Hits	90
SwissProt Accessions	Q9Y2I2, Q5VU86, Q5VU87, Q5VU89, Q5VU90, Q5VU91, Q7Z2Y3, Q8N633	Gene names	NTNG1, KIAA0976, LMNT1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

NTNG1_MOUSE
θ value	θ > 10 (rank : 365)	NC score	0.081241 (rank : 328)
Query Neighborhood Hits	162	Target Neighborhood Hits	246	Shared Neighborhood Hits	88
SwissProt Accessions	Q8R4G0, Q68FE5, Q69ZU3, Q8R4F3, Q8R4F4, Q8R4F5, Q8R4F6, Q8R4F7, Q8R4F8, Q8R4F9, Q9ESR3, Q9ESR4, Q9ESR5, Q9ESR6, Q9ESR7, Q9ESR8	Gene names	Ntng1, Kiaa0976, Lmnt1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

NTNG2_MOUSE
θ value	θ > 10 (rank : 366)	NC score	0.095822 (rank : 283)
Query Neighborhood Hits	162	Target Neighborhood Hits	276	Shared Neighborhood Hits	99
SwissProt Accessions	Q8R4F1, Q8R4F2, Q8VIP6, Q8VIP7, Q8VIP8	Gene names	Ntng2, Lmnt2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

PCOC1_HUMAN
θ value	θ > 10 (rank : 367)	NC score	0.183996 (rank : 100)
Query Neighborhood Hits	162	Target Neighborhood Hits	146	Shared Neighborhood Hits	13
SwissProt Accessions	Q15113, O14550	Gene names	PCOLCE, PCPE1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein).

PCOC1_MOUSE
θ value	θ > 10 (rank : 368)	NC score	0.184637 (rank : 99)
Query Neighborhood Hits	162	Target Neighborhood Hits	100	Shared Neighborhood Hits	13
SwissProt Accessions	Q61398, O35113	Gene names	Pcolce, Pcpe1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein) (P14).

PCOC2_HUMAN
θ value	θ > 10 (rank : 369)	NC score	0.186138 (rank : 94)
Query Neighborhood Hits	162	Target Neighborhood Hits	73	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UKZ9, Q9BRH3	Gene names	PCOLCE2, PCPE2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

PCOC2_MOUSE
θ value	θ > 10 (rank : 370)	NC score	0.188112 (rank : 91)
Query Neighborhood Hits	162	Target Neighborhood Hits	73	Shared Neighborhood Hits	13
SwissProt Accessions	Q8R4W6, Q3V1K6, Q9CX06	Gene names	Pcolce2, Pcpe2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

PCSK5_MOUSE
θ value	θ > 10 (rank : 371)	NC score	0.075976 (rank : 351)
Query Neighborhood Hits	162	Target Neighborhood Hits	613	Shared Neighborhood Hits	100
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

PDGFD_HUMAN
θ value	θ > 10 (rank : 372)	NC score	0.162912 (rank : 146)
Query Neighborhood Hits	162	Target Neighborhood Hits	74	Shared Neighborhood Hits	13
SwissProt Accessions	Q9GZP0, Q9BWV5	Gene names	PDGFD, IEGF, SCDGFB
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor D precursor (PDGF D) (Iris-expressed growth factor) (Spinal cord-derived growth factor B) (SCDGF-B).

PDGFD_MOUSE
θ value	θ > 10 (rank : 373)	NC score	0.166950 (rank : 133)
Query Neighborhood Hits	162	Target Neighborhood Hits	72	Shared Neighborhood Hits	13
SwissProt Accessions	Q925I7, Q3URF6, Q8K2L3, Q9D1L8	Gene names	Pdgfd, Scdgfb
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor chain precursor (PDGF D) (Spinal cord- derived growth factor B) (SCDGF-B).

PERT_HUMAN
θ value	θ > 10 (rank : 374)	NC score	0.093501 (rank : 289)
Query Neighborhood Hits	162	Target Neighborhood Hits	221	Shared Neighborhood Hits	91
SwissProt Accessions	P07202, P09934, P09935, Q8IUL0, Q8NF94, Q8NF95, Q8NF96, Q8NF97, Q8TCI9	Gene names	TPO
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

PERT_MOUSE
θ value	θ > 10 (rank : 375)	NC score	0.086528 (rank : 312)
Query Neighborhood Hits	162	Target Neighborhood Hits	221	Shared Neighborhood Hits	82
SwissProt Accessions	P35419, Q8C8B1	Gene names	Tpo
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

PGBM_HUMAN
θ value	θ > 10 (rank : 376)	NC score	0.105696 (rank : 255)
Query Neighborhood Hits	162	Target Neighborhood Hits	1113	Shared Neighborhood Hits	129
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

PGBM_MOUSE
θ value	θ > 10 (rank : 377)	NC score	0.103429 (rank : 264)
Query Neighborhood Hits	162	Target Neighborhood Hits	1073	Shared Neighborhood Hits	129
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

PGCA_HUMAN
θ value	θ > 10 (rank : 378)	NC score	0.067684 (rank : 390)
Query Neighborhood Hits	162	Target Neighborhood Hits	821	Shared Neighborhood Hits	104
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

PGH1_HUMAN
θ value	θ > 10 (rank : 379)	NC score	0.076226 (rank : 349)
Query Neighborhood Hits	162	Target Neighborhood Hits	91	Shared Neighborhood Hits	61
SwissProt Accessions	P23219, Q15122	Gene names	PTGS1, COX1
Domain Architecture
Description	Prostaglandin G/H synthase 1 precursor (EC 1.14.99.1) (Cyclooxygenase- 1) (COX-1) (Prostaglandin-endoperoxide synthase 1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1).

PHXR5_MOUSE
θ value	θ > 10 (rank : 380)	NC score	0.072848 (rank : 369)
Query Neighborhood Hits	162	Target Neighborhood Hits	102	Shared Neighborhood Hits	40
SwissProt Accessions	P08399	Gene names	Phxr5, Per
Domain Architecture	No domain graphic available
Description	Per-hexamer repeat protein 5.

PROC_HUMAN
θ value	θ > 10 (rank : 381)	NC score	0.098898 (rank : 271)
Query Neighborhood Hits	162	Target Neighborhood Hits	406	Shared Neighborhood Hits	119
SwissProt Accessions	P04070, Q15189, Q15190, Q16001	Gene names	PROC
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

PROC_MOUSE
θ value	θ > 10 (rank : 382)	NC score	0.106848 (rank : 249)
Query Neighborhood Hits	162	Target Neighborhood Hits	426	Shared Neighborhood Hits	124
SwissProt Accessions	P33587, O35498, Q91WN8, Q99PC6	Gene names	Proc
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

SCUB3_HUMAN
θ value	θ > 10 (rank : 383)	NC score	0.199421 (rank : 75)
Query Neighborhood Hits	162	Target Neighborhood Hits	428	Shared Neighborhood Hits	115
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SCUB3_MOUSE
θ value	θ > 10 (rank : 384)	NC score	0.199855 (rank : 72)
Query Neighborhood Hits	162	Target Neighborhood Hits	442	Shared Neighborhood Hits	116
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

SEZ6L_HUMAN
θ value	θ > 10 (rank : 385)	NC score	0.138275 (rank : 191)
Query Neighborhood Hits	162	Target Neighborhood Hits	289	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

SMDF_HUMAN
θ value	θ > 10 (rank : 386)	NC score	0.069024 (rank : 386)
Query Neighborhood Hits	162	Target Neighborhood Hits	117	Shared Neighborhood Hits	53
SwissProt Accessions	Q15491	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture	No domain graphic available
Description	Neuregulin-1, sensory and motor neuron-derived factor isoform.

SORL_HUMAN
θ value	θ > 10 (rank : 387)	NC score	0.073191 (rank : 365)
Query Neighborhood Hits	162	Target Neighborhood Hits	440	Shared Neighborhood Hits	77
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

SORL_MOUSE
θ value	θ > 10 (rank : 388)	NC score	0.076748 (rank : 347)
Query Neighborhood Hits	162	Target Neighborhood Hits	439	Shared Neighborhood Hits	81
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

SREC2_HUMAN
θ value	θ > 10 (rank : 389)	NC score	0.134678 (rank : 198)
Query Neighborhood Hits	162	Target Neighborhood Hits	645	Shared Neighborhood Hits	109
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

SREC2_MOUSE
θ value	θ > 10 (rank : 390)	NC score	0.135061 (rank : 197)
Query Neighborhood Hits	162	Target Neighborhood Hits	605	Shared Neighborhood Hits	111
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

SREC_HUMAN
θ value	θ > 10 (rank : 391)	NC score	0.139391 (rank : 186)
Query Neighborhood Hits	162	Target Neighborhood Hits	645	Shared Neighborhood Hits	113
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

SSPO_MOUSE
θ value	θ > 10 (rank : 392)	NC score	0.076478 (rank : 348)
Query Neighborhood Hits	162	Target Neighborhood Hits	800	Shared Neighborhood Hits	107
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

ST14_HUMAN
θ value	θ > 10 (rank : 393)	NC score	0.099430 (rank : 270)
Query Neighborhood Hits	162	Target Neighborhood Hits	409	Shared Neighborhood Hits	79
SwissProt Accessions	Q9Y5Y6, Q9BS01, Q9H3S0, Q9HB36, Q9HCA3	Gene names	ST14, PRSS14, SNC19, TADG15
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein).

ST14_MOUSE
θ value	θ > 10 (rank : 394)	NC score	0.100620 (rank : 269)
Query Neighborhood Hits	162	Target Neighborhood Hits	419	Shared Neighborhood Hits	89
SwissProt Accessions	P56677	Gene names	St14, Prss14
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Epithin).

STAB1_HUMAN
θ value	θ > 10 (rank : 395)	NC score	0.150101 (rank : 162)
Query Neighborhood Hits	162	Target Neighborhood Hits	546	Shared Neighborhood Hits	129
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

STAB1_MOUSE
θ value	θ > 10 (rank : 396)	NC score	0.153585 (rank : 158)
Query Neighborhood Hits	162	Target Neighborhood Hits	566	Shared Neighborhood Hits	129
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

STAB2_MOUSE
θ value	θ > 10 (rank : 397)	NC score	0.141576 (rank : 180)
Query Neighborhood Hits	162	Target Neighborhood Hits	528	Shared Neighborhood Hits	122
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

SUSD1_HUMAN
θ value	θ > 10 (rank : 398)	NC score	0.170513 (rank : 126)
Query Neighborhood Hits	162	Target Neighborhood Hits	285	Shared Neighborhood Hits	112
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

TDGF1_HUMAN
θ value	θ > 10 (rank : 399)	NC score	0.085570 (rank : 314)
Query Neighborhood Hits	162	Target Neighborhood Hits	132	Shared Neighborhood Hits	78
SwissProt Accessions	P13385	Gene names	TDGF1, CRIPTO
Domain Architecture
Description	Teratocarcinoma-derived growth factor 1 precursor (Epidermal growth factor-like cripto protein CR1) (Cripto-1 growth factor) (CRGF).

TDGF1_MOUSE
θ value	θ > 10 (rank : 400)	NC score	0.097139 (rank : 278)
Query Neighborhood Hits	162	Target Neighborhood Hits	146	Shared Neighborhood Hits	81
SwissProt Accessions	P51865	Gene names	Tdgf1, Cripto
Domain Architecture
Description	Teratocarcinoma-derived growth factor precursor (Epidermal growth factor-like Cripto protein) (Cripto growth factor).

TDGF2_HUMAN
θ value	θ > 10 (rank : 401)	NC score	0.081763 (rank : 327)
Query Neighborhood Hits	162	Target Neighborhood Hits	131	Shared Neighborhood Hits	77
SwissProt Accessions	P51864	Gene names	TDGF3, TDGF2
Domain Architecture
Description	Teratocarcinoma-derived growth factor 2 (Epidermal growth factor-like cripto protein CR3) (Cripto-3 growth factor).

TECTA_MOUSE
θ value	θ > 10 (rank : 402)	NC score	0.058381 (rank : 411)
Query Neighborhood Hits	162	Target Neighborhood Hits	244	Shared Neighborhood Hits	76
SwissProt Accessions	O08523	Gene names	Tecta
Domain Architecture
Description	Alpha-tectorin precursor.

TEFF2_HUMAN
θ value	θ > 10 (rank : 403)	NC score	0.080803 (rank : 329)
Query Neighborhood Hits	162	Target Neighborhood Hits	211	Shared Neighborhood Hits	68
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

TEFF2_MOUSE
θ value	θ > 10 (rank : 404)	NC score	0.080582 (rank : 331)
Query Neighborhood Hits	162	Target Neighborhood Hits	214	Shared Neighborhood Hits	71
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

TENA_HUMAN
θ value	θ > 10 (rank : 405)	NC score	0.122001 (rank : 224)
Query Neighborhood Hits	162	Target Neighborhood Hits	631	Shared Neighborhood Hits	116
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

TENA_MOUSE
θ value	θ > 10 (rank : 406)	NC score	0.119670 (rank : 230)
Query Neighborhood Hits	162	Target Neighborhood Hits	596	Shared Neighborhood Hits	111
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

TENN_HUMAN
θ value	θ > 10 (rank : 407)	NC score	0.060065 (rank : 404)
Query Neighborhood Hits	162	Target Neighborhood Hits	453	Shared Neighborhood Hits	84
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

TENN_MOUSE
θ value	θ > 10 (rank : 408)	NC score	0.065197 (rank : 395)
Query Neighborhood Hits	162	Target Neighborhood Hits	484	Shared Neighborhood Hits	83
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

TENR_HUMAN
θ value	θ > 10 (rank : 409)	NC score	0.078602 (rank : 336)
Query Neighborhood Hits	162	Target Neighborhood Hits	526	Shared Neighborhood Hits	100
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

TENR_MOUSE
θ value	θ > 10 (rank : 410)	NC score	0.079101 (rank : 335)
Query Neighborhood Hits	162	Target Neighborhood Hits	531	Shared Neighborhood Hits	101
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

TENX_HUMAN
θ value	θ > 10 (rank : 411)	NC score	0.121127 (rank : 227)
Query Neighborhood Hits	162	Target Neighborhood Hits	789	Shared Neighborhood Hits	116
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

TMPS6_HUMAN
θ value	θ > 10 (rank : 412)	NC score	0.056507 (rank : 420)
Query Neighborhood Hits	162	Target Neighborhood Hits	338	Shared Neighborhood Hits	63
SwissProt Accessions	Q8IU80, Q5TI06, Q6UXD8, Q8IUE2, Q8IXV8	Gene names	TMPRSS6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

TMPS6_MOUSE
θ value	θ > 10 (rank : 413)	NC score	0.052926 (rank : 429)
Query Neighborhood Hits	162	Target Neighborhood Hits	341	Shared Neighborhood Hits	64
SwissProt Accessions	Q9DBI0, Q6PF94	Gene names	Tmprss6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

TPA_HUMAN
θ value	θ > 10 (rank : 414)	NC score	0.064330 (rank : 398)
Query Neighborhood Hits	162	Target Neighborhood Hits	324	Shared Neighborhood Hits	93
SwissProt Accessions	P00750, Q15103, Q7Z7N2, Q86YK8, Q9BU99	Gene names	PLAT
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) (Alteplase) (Reteplase) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

TPA_MOUSE
θ value	θ > 10 (rank : 415)	NC score	0.066904 (rank : 392)
Query Neighborhood Hits	162	Target Neighborhood Hits	335	Shared Neighborhood Hits	95
SwissProt Accessions	P11214, Q91VP2	Gene names	Plat
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

TRAF5_HUMAN
θ value	θ > 10 (rank : 416)	NC score	0.130625 (rank : 205)
Query Neighborhood Hits	162	Target Neighborhood Hits	396	Shared Neighborhood Hits	14
SwissProt Accessions	O00463	Gene names	TRAF5, RNF84
Domain Architecture
Description	TNF receptor-associated factor 5 (RING finger protein 84).

TRAF5_MOUSE
θ value	θ > 10 (rank : 417)	NC score	0.139181 (rank : 188)
Query Neighborhood Hits	162	Target Neighborhood Hits	355	Shared Neighborhood Hits	13
SwissProt Accessions	P70191, Q61480	Gene names	Traf5
Domain Architecture
Description	TNF receptor-associated factor 5.

TRBM_HUMAN
θ value	θ > 10 (rank : 418)	NC score	0.175470 (rank : 119)
Query Neighborhood Hits	162	Target Neighborhood Hits	339	Shared Neighborhood Hits	109
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

TRBM_MOUSE
θ value	θ > 10 (rank : 419)	NC score	0.172131 (rank : 121)
Query Neighborhood Hits	162	Target Neighborhood Hits	361	Shared Neighborhood Hits	107
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

TSG6_HUMAN
θ value	θ > 10 (rank : 420)	NC score	0.163003 (rank : 145)
Query Neighborhood Hits	162	Target Neighborhood Hits	91	Shared Neighborhood Hits	21
SwissProt Accessions	P98066, Q8WWI9	Gene names	TNFAIP6, TSG6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein) (Hyaluronate-binding protein).

TSG6_MOUSE
θ value	θ > 10 (rank : 421)	NC score	0.161927 (rank : 147)
Query Neighborhood Hits	162	Target Neighborhood Hits	91	Shared Neighborhood Hits	20
SwissProt Accessions	O08859	Gene names	Tnfaip6, Tnfip6, Tsg6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein).

TSP1_HUMAN
θ value	θ > 10 (rank : 422)	NC score	0.082599 (rank : 322)
Query Neighborhood Hits	162	Target Neighborhood Hits	389	Shared Neighborhood Hits	97
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

TSP1_MOUSE
θ value	θ > 10 (rank : 423)	NC score	0.084752 (rank : 315)
Query Neighborhood Hits	162	Target Neighborhood Hits	396	Shared Neighborhood Hits	99
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

TSP2_HUMAN
θ value	θ > 10 (rank : 424)	NC score	0.075897 (rank : 352)
Query Neighborhood Hits	162	Target Neighborhood Hits	359	Shared Neighborhood Hits	95
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

TSP2_MOUSE
θ value	θ > 10 (rank : 425)	NC score	0.073184 (rank : 366)
Query Neighborhood Hits	162	Target Neighborhood Hits	352	Shared Neighborhood Hits	96
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

TSP3_HUMAN
θ value	θ > 10 (rank : 426)	NC score	0.132796 (rank : 203)
Query Neighborhood Hits	162	Target Neighborhood Hits	250	Shared Neighborhood Hits	110
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

TSP3_MOUSE
θ value	θ > 10 (rank : 427)	NC score	0.133190 (rank : 201)
Query Neighborhood Hits	162	Target Neighborhood Hits	247	Shared Neighborhood Hits	108
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

TSP4_HUMAN
θ value	θ > 10 (rank : 428)	NC score	0.146423 (rank : 168)
Query Neighborhood Hits	162	Target Neighborhood Hits	277	Shared Neighborhood Hits	115
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

TSP4_MOUSE
θ value	θ > 10 (rank : 429)	NC score	0.149074 (rank : 165)
Query Neighborhood Hits	162	Target Neighborhood Hits	276	Shared Neighborhood Hits	115
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

UROL1_HUMAN
θ value	θ > 10 (rank : 430)	NC score	0.077804 (rank : 342)
Query Neighborhood Hits	162	Target Neighborhood Hits	213	Shared Neighborhood Hits	71
SwissProt Accessions	Q5DID0, Q5DIC9, Q6LA40, Q6LA41, Q8N216	Gene names	UMODL1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

UROL1_MOUSE
θ value	θ > 10 (rank : 431)	NC score	0.095923 (rank : 282)
Query Neighborhood Hits	162	Target Neighborhood Hits	235	Shared Neighborhood Hits	79
SwissProt Accessions	Q5DID3, Q5DID1, Q5DID2	Gene names	Umodl1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

UROM_HUMAN
θ value	θ > 10 (rank : 432)	NC score	0.160231 (rank : 152)
Query Neighborhood Hits	162	Target Neighborhood Hits	284	Shared Neighborhood Hits	116
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

UROM_MOUSE
θ value	θ > 10 (rank : 433)	NC score	0.166453 (rank : 135)
Query Neighborhood Hits	162	Target Neighborhood Hits	276	Shared Neighborhood Hits	118
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

USH2A_HUMAN
θ value	θ > 10 (rank : 434)	NC score	0.069121 (rank : 385)
Query Neighborhood Hits	162	Target Neighborhood Hits	600	Shared Neighborhood Hits	89
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

USH2A_MOUSE
θ value	θ > 10 (rank : 435)	NC score	0.070160 (rank : 382)
Query Neighborhood Hits	162	Target Neighborhood Hits	626	Shared Neighborhood Hits	92
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

VWF_HUMAN
θ value	θ > 10 (rank : 436)	NC score	0.053287 (rank : 426)
Query Neighborhood Hits	162	Target Neighborhood Hits	396	Shared Neighborhood Hits	71
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

Hits sorted by NC score

MEP1A_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	162	Target Neighborhood Hits	162	Shared Neighborhood Hits	162
SwissProt Accessions	Q16819	Gene names	MEP1A
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit alpha) (PABA peptide hydrolase) (PPH alpha).

MEP1A_MOUSE
NC score	0.988926 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	162	Target Neighborhood Hits	166	Shared Neighborhood Hits	150
SwissProt Accessions	P28825	Gene names	Mep1a
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (MEP-1).

MEP1B_MOUSE
NC score	0.944689 (rank : 3)	θ value	2.51683e-135 (rank : 4)
Query Neighborhood Hits	162	Target Neighborhood Hits	127	Shared Neighborhood Hits	99
SwissProt Accessions	Q61847	Gene names	Mep1b, Mep-1b
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2).

MEP1B_HUMAN
NC score	0.939359 (rank : 4)	θ value	3.06949e-141 (rank : 3)
Query Neighborhood Hits	162	Target Neighborhood Hits	98	Shared Neighborhood Hits	76
SwissProt Accessions	Q16820, Q670J1	Gene names	MEP1B
Domain Architecture
Description	Meprin A subunit beta precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit beta) (PABA peptide hydrolase) (PPH beta).

ASTL_MOUSE
NC score	0.749189 (rank : 5)	θ value	1.57365e-28 (rank : 5)
Query Neighborhood Hits	162	Target Neighborhood Hits	20	Shared Neighborhood Hits	14
SwissProt Accessions	Q6HA09, Q8BMA1	Gene names	Astl
Domain Architecture	No domain graphic available
Description	Astacin-like metalloendopeptidase precursor (EC 3.4.-.-) (Oocyte astacin) (Ovastacin).

ASTL_HUMAN
NC score	0.705515 (rank : 6)	θ value	1.33217e-27 (rank : 6)
Query Neighborhood Hits	162	Target Neighborhood Hits	252	Shared Neighborhood Hits	18
SwissProt Accessions	Q6HA08	Gene names	ASTL
Domain Architecture	No domain graphic available
Description	Astacin-like metalloendopeptidase precursor (EC 3.4.-.-) (Oocyte astacin) (Ovastacin).

TLL2_HUMAN
NC score	0.466946 (rank : 7)	θ value	2.20094e-22 (rank : 10)
Query Neighborhood Hits	162	Target Neighborhood Hits	241	Shared Neighborhood Hits	95
SwissProt Accessions	Q9Y6L7, Q6PJN5, Q9UQ00	Gene names	TLL2, KIAA0932
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

TLL1_MOUSE
NC score	0.465593 (rank : 8)	θ value	2.20094e-22 (rank : 9)
Query Neighborhood Hits	162	Target Neighborhood Hits	237	Shared Neighborhood Hits	91
SwissProt Accessions	Q62381, Q3UTT9, Q8BNP5	Gene names	Tll1, Tll
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-) (mTll).

BMP1_HUMAN
NC score	0.465076 (rank : 9)	θ value	1.29031e-22 (rank : 7)
Query Neighborhood Hits	162	Target Neighborhood Hits	233	Shared Neighborhood Hits	89
SwissProt Accessions	P13497, Q13292, Q13872, Q14874, Q99421, Q99422, Q99423, Q9UL38	Gene names	BMP1, PCOLC
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

TLL1_HUMAN
NC score	0.464024 (rank : 10)	θ value	3.75424e-22 (rank : 12)
Query Neighborhood Hits	162	Target Neighborhood Hits	236	Shared Neighborhood Hits	89
SwissProt Accessions	O43897, Q96AN3, Q9NQS4	Gene names	TLL1, TLL
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 1 precursor (EC 3.4.24.-).

BMP1_MOUSE
NC score	0.463992 (rank : 11)	θ value	1.6852e-22 (rank : 8)
Query Neighborhood Hits	162	Target Neighborhood Hits	236	Shared Neighborhood Hits	90
SwissProt Accessions	P98063	Gene names	Bmp1
Domain Architecture
Description	Bone morphogenetic protein 1 precursor (EC 3.4.24.19) (BMP-1) (Procollagen C-proteinase) (PCP) (Mammalian tolloid protein) (mTld).

TLL2_MOUSE
NC score	0.462656 (rank : 12)	θ value	2.20094e-22 (rank : 11)
Query Neighborhood Hits	162	Target Neighborhood Hits	240	Shared Neighborhood Hits	89
SwissProt Accessions	Q9WVM6	Gene names	Tll2
Domain Architecture	No domain graphic available
Description	Tolloid-like protein 2 precursor (EC 3.4.24.-).

MAMC2_MOUSE
NC score	0.327186 (rank : 13)	θ value	1.29631e-06 (rank : 17)
Query Neighborhood Hits	162	Target Neighborhood Hits	31	Shared Neighborhood Hits	16
SwissProt Accessions	Q8CG85, Q8BM24	Gene names	Mamdc2
Domain Architecture
Description	MAM domain-containing protein 2 precursor.

MAMC2_HUMAN
NC score	0.314254 (rank : 14)	θ value	5.44631e-05 (rank : 25)
Query Neighborhood Hits	162	Target Neighborhood Hits	31	Shared Neighborhood Hits	16
SwissProt Accessions	Q7Z304, Q5VW47, Q8WX43, Q96BM4	Gene names	MAMDC2
Domain Architecture
Description	MAM domain-containing protein 2 precursor.

CUBN_MOUSE
NC score	0.294214 (rank : 15)	θ value	0.279714 (rank : 79)
Query Neighborhood Hits	162	Target Neighborhood Hits	477	Shared Neighborhood Hits	137
SwissProt Accessions	Q9JLB4	Gene names	Cubn, Ifcr
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor).

CUBN_HUMAN
NC score	0.289640 (rank : 16)	θ value	2.36792 (rank : 127)
Query Neighborhood Hits	162	Target Neighborhood Hits	482	Shared Neighborhood Hits	139
SwissProt Accessions	O60494, Q5VTA6, Q96RU9	Gene names	CUBN, IFCR
Domain Architecture	No domain graphic available
Description	Cubilin precursor (Intrinsic factor-cobalamin receptor) (Intrinsic factor-vitamin B12 receptor) (460 kDa receptor) (Intestinal intrinsic factor receptor).

NRP1_MOUSE
NC score	0.279372 (rank : 17)	θ value	1.87187e-05 (rank : 21)
Query Neighborhood Hits	162	Target Neighborhood Hits	120	Shared Neighborhood Hits	29
SwissProt Accessions	P97333	Gene names	Nrp1, Nrp
Domain Architecture
Description	Neuropilin-1 precursor (A5 protein).

NRP1_HUMAN
NC score	0.277458 (rank : 18)	θ value	5.44631e-05 (rank : 26)
Query Neighborhood Hits	162	Target Neighborhood Hits	119	Shared Neighborhood Hits	29
SwissProt Accessions	O14786, O60461, Q96IH5	Gene names	NRP1, NRP, VEGF165R
Domain Architecture
Description	Neuropilin-1 precursor (Vascular endothelial cell growth factor 165 receptor) (CD304 antigen).

DLK_MOUSE
NC score	0.245122 (rank : 19)	θ value	0.00134147 (rank : 32)
Query Neighborhood Hits	162	Target Neighborhood Hits	374	Shared Neighborhood Hits	128
SwissProt Accessions	Q09163, Q07645, Q62208	Gene names	Dlk1, Dlk, Pref1, Scp-1
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (Preadipocyte factor 1) (Pref-1) (Adipocyte differentiation inhibitor protein) [Contains: Fetal antigen 1 (FA1)].

DLK_HUMAN
NC score	0.244912 (rank : 20)	θ value	0.000602161 (rank : 27)
Query Neighborhood Hits	162	Target Neighborhood Hits	401	Shared Neighborhood Hits	129
SwissProt Accessions	P80370, P15803, Q96DW5	Gene names	DLK1, DLK
Domain Architecture	No domain graphic available
Description	Delta-like protein precursor (DLK) (pG2) [Contains: Fetal antigen 1 (FA1)].

CRUM1_HUMAN
NC score	0.242805 (rank : 21)	θ value	0.0252991 (rank : 47)
Query Neighborhood Hits	162	Target Neighborhood Hits	457	Shared Neighborhood Hits	135
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

DLL3_MOUSE
NC score	0.238989 (rank : 22)	θ value	0.0330416 (rank : 51)
Query Neighborhood Hits	162	Target Neighborhood Hits	399	Shared Neighborhood Hits	129
SwissProt Accessions	O88516, O35675, Q80W06, Q9QWL9, Q9QWZ7	Gene names	Dll3
Domain Architecture	No domain graphic available
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3) (M-Delta- 3).

TRAF4_MOUSE
NC score	0.238653 (rank : 23)	θ value	2.21117e-06 (rank : 19)
Query Neighborhood Hits	162	Target Neighborhood Hits	338	Shared Neighborhood Hits	14
SwissProt Accessions	Q61382	Gene names	Traf4, Cart1
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich motif associated to RING and Traf domains protein 1).

EDIL3_HUMAN
NC score	0.234810 (rank : 24)	θ value	0.00665767 (rank : 38)
Query Neighborhood Hits	162	Target Neighborhood Hits	292	Shared Neighborhood Hits	133
SwissProt Accessions	O43854, O43855	Gene names	EDIL3, DEL1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

TRAF4_HUMAN
NC score	0.233543 (rank : 25)	θ value	1.29631e-06 (rank : 18)
Query Neighborhood Hits	162	Target Neighborhood Hits	373	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BUZ4, O75615, Q14848, Q2PJN8	Gene names	TRAF4, CART1, MLN62, RNF83
Domain Architecture
Description	TNF receptor-associated factor 4 (Cysteine-rich domain associated with RING and Traf domains protein 1) (Malignant 62) (RING finger protein 83).

EDIL3_MOUSE
NC score	0.232314 (rank : 26)	θ value	0.0252991 (rank : 48)
Query Neighborhood Hits	162	Target Neighborhood Hits	317	Shared Neighborhood Hits	130
SwissProt Accessions	O35474, O35475	Gene names	Edil3, Del1
Domain Architecture
Description	EGF-like repeat and discoidin I-like domain-containing protein 3 precursor (EGF-like repeats and discoidin I-like domains protein 3) (Developmentally-regulated endothelial cell locus 1 protein) (Integrin-binding protein DEL1).

CRUM1_MOUSE
NC score	0.232293 (rank : 27)	θ value	0.279714 (rank : 77)
Query Neighborhood Hits	162	Target Neighborhood Hits	444	Shared Neighborhood Hits	134
SwissProt Accessions	Q8VHS2, Q6ST50, Q71JF2, Q8BGR4	Gene names	Crb1
Domain Architecture	No domain graphic available
Description	Crumbs homolog 1 precursor.

DLL1_HUMAN
NC score	0.231826 (rank : 28)	θ value	0.0193708 (rank : 44)
Query Neighborhood Hits	162	Target Neighborhood Hits	455	Shared Neighborhood Hits	135
SwissProt Accessions	O00548, Q9NU41, Q9UJV2	Gene names	DLL1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1) (H-Delta-1).

NRP2_HUMAN
NC score	0.229523 (rank : 29)	θ value	0.0431538 (rank : 53)
Query Neighborhood Hits	162	Target Neighborhood Hits	120	Shared Neighborhood Hits	29
SwissProt Accessions	O60462, O14820, O14821	Gene names	NRP2, VEGF165R2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

DLL3_HUMAN
NC score	0.229174 (rank : 30)	θ value	0.125558 (rank : 64)
Query Neighborhood Hits	162	Target Neighborhood Hits	419	Shared Neighborhood Hits	129
SwissProt Accessions	Q9NYJ7	Gene names	DLL3
Domain Architecture
Description	Delta-like protein 3 precursor (Drosophila Delta homolog 3).

CRUM2_HUMAN
NC score	0.228874 (rank : 31)	θ value	0.47712 (rank : 92)
Query Neighborhood Hits	162	Target Neighborhood Hits	453	Shared Neighborhood Hits	135
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

DNER_MOUSE
NC score	0.228854 (rank : 32)	θ value	0.163984 (rank : 68)
Query Neighborhood Hits	162	Target Neighborhood Hits	413	Shared Neighborhood Hits	131
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

NOTC1_MOUSE
NC score	0.227346 (rank : 33)	θ value	0.00102713 (rank : 30)
Query Neighborhood Hits	162	Target Neighborhood Hits	916	Shared Neighborhood Hits	139
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

DNER_HUMAN
NC score	0.227240 (rank : 34)	θ value	0.279714 (rank : 81)
Query Neighborhood Hits	162	Target Neighborhood Hits	460	Shared Neighborhood Hits	131
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

FBN1_MOUSE
NC score	0.226704 (rank : 35)	θ value	0.0148317 (rank : 42)
Query Neighborhood Hits	162	Target Neighborhood Hits	563	Shared Neighborhood Hits	128
SwissProt Accessions	Q61554, Q60826	Gene names	Fbn1, Fbn-1
Domain Architecture
Description	Fibrillin-1 precursor.

NOTC2_MOUSE
NC score	0.225887 (rank : 36)	θ value	3.19293e-05 (rank : 22)
Query Neighborhood Hits	162	Target Neighborhood Hits	1069	Shared Neighborhood Hits	138
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

DLL4_MOUSE
NC score	0.225698 (rank : 37)	θ value	0.0961366 (rank : 58)
Query Neighborhood Hits	162	Target Neighborhood Hits	440	Shared Neighborhood Hits	136
SwissProt Accessions	Q9JI71, Q9JHZ7	Gene names	Dll4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

NOTC2_HUMAN
NC score	0.225369 (rank : 38)	θ value	1.43324e-05 (rank : 20)
Query Neighborhood Hits	162	Target Neighborhood Hits	1113	Shared Neighborhood Hits	138
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

LTBP3_MOUSE
NC score	0.224145 (rank : 39)	θ value	0.0563607 (rank : 55)
Query Neighborhood Hits	162	Target Neighborhood Hits	475	Shared Neighborhood Hits	122
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

FBN3_HUMAN
NC score	0.223367 (rank : 40)	θ value	0.365318 (rank : 89)
Query Neighborhood Hits	162	Target Neighborhood Hits	543	Shared Neighborhood Hits	128
SwissProt Accessions	Q75N90, Q75N91, Q75N92, Q75N93, Q86SJ5, Q96JP8	Gene names	FBN3, KIAA1776
Domain Architecture	No domain graphic available
Description	Fibrillin-3 precursor.

FBN1_HUMAN
NC score	0.223085 (rank : 41)	θ value	0.0961366 (rank : 60)
Query Neighborhood Hits	162	Target Neighborhood Hits	557	Shared Neighborhood Hits	127
SwissProt Accessions	P35555, Q15972, Q75N87	Gene names	FBN1, FBN
Domain Architecture
Description	Fibrillin-1 precursor.

DLL1_MOUSE
NC score	0.223013 (rank : 42)	θ value	1.06291 (rank : 105)
Query Neighborhood Hits	162	Target Neighborhood Hits	456	Shared Neighborhood Hits	135
SwissProt Accessions	Q61483	Gene names	Dll1
Domain Architecture
Description	Delta-like protein 1 precursor (Drosophila Delta homolog 1) (Delta1).

C1QR1_MOUSE
NC score	0.222362 (rank : 43)	θ value	0.62314 (rank : 93)
Query Neighborhood Hits	162	Target Neighborhood Hits	342	Shared Neighborhood Hits	126
SwissProt Accessions	O89103, Q3U2X0	Gene names	Cd93, Aa4, C1qr1, C1qrp, Ly68
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (Cell surface antigen AA4) (Lymphocyte antigen 68).

FBN2_MOUSE
NC score	0.221776 (rank : 44)	θ value	0.0961366 (rank : 61)
Query Neighborhood Hits	162	Target Neighborhood Hits	549	Shared Neighborhood Hits	129
SwissProt Accessions	Q61555, Q63957	Gene names	Fbn2, Fbn-2
Domain Architecture
Description	Fibrillin-2 precursor.

PROS_HUMAN
NC score	0.221646 (rank : 45)	θ value	3.0926 (rank : 135)
Query Neighborhood Hits	162	Target Neighborhood Hits	340	Shared Neighborhood Hits	124
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

DLL4_HUMAN
NC score	0.221175 (rank : 46)	θ value	0.279714 (rank : 80)
Query Neighborhood Hits	162	Target Neighborhood Hits	435	Shared Neighborhood Hits	131
SwissProt Accessions	Q9NR61, Q9NQT9	Gene names	DLL4
Domain Architecture
Description	Delta-like protein 4 precursor (Drosophila Delta homolog 4).

NOTC1_HUMAN
NC score	0.221051 (rank : 47)	θ value	0.00665767 (rank : 39)
Query Neighborhood Hits	162	Target Neighborhood Hits	906	Shared Neighborhood Hits	139
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

FBN2_HUMAN
NC score	0.220917 (rank : 48)	θ value	0.125558 (rank : 65)
Query Neighborhood Hits	162	Target Neighborhood Hits	560	Shared Neighborhood Hits	127
SwissProt Accessions	P35556	Gene names	FBN2
Domain Architecture
Description	Fibrillin-2 precursor.

NOTC3_MOUSE
NC score	0.218690 (rank : 49)	θ value	0.00298849 (rank : 35)
Query Neighborhood Hits	162	Target Neighborhood Hits	975	Shared Neighborhood Hits	138
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

JAG1_HUMAN
NC score	0.218676 (rank : 50)	θ value	0.163984 (rank : 69)
Query Neighborhood Hits	162	Target Neighborhood Hits	514	Shared Neighborhood Hits	136
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

LTBP2_MOUSE
NC score	0.217286 (rank : 51)	θ value	0.21417 (rank : 76)
Query Neighborhood Hits	162	Target Neighborhood Hits	617	Shared Neighborhood Hits	129
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

JAG1_MOUSE
NC score	0.216807 (rank : 52)	θ value	0.163984 (rank : 70)
Query Neighborhood Hits	162	Target Neighborhood Hits	518	Shared Neighborhood Hits	134
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

EGFL7_HUMAN
NC score	0.216728 (rank : 53)	θ value	θ > 10 (rank : 207)
Query Neighborhood Hits	162	Target Neighborhood Hits	325	Shared Neighborhood Hits	118
SwissProt Accessions	Q9UHF1, Q5M7Y5, Q5VUD5, Q96EG0	Gene names	EGFL7, MEGF7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (ZNEU1).

EGFL9_HUMAN
NC score	0.216307 (rank : 54)	θ value	1.81305 (rank : 121)
Query Neighborhood Hits	162	Target Neighborhood Hits	365	Shared Neighborhood Hits	127
SwissProt Accessions	Q6UY11, Q9BQ54	Gene names	EGFL9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9).

NOTC3_HUMAN
NC score	0.215628 (rank : 55)	θ value	0.00665767 (rank : 40)
Query Neighborhood Hits	162	Target Neighborhood Hits	1062	Shared Neighborhood Hits	137
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

PROS_MOUSE
NC score	0.214392 (rank : 56)	θ value	1.38821 (rank : 118)
Query Neighborhood Hits	162	Target Neighborhood Hits	330	Shared Neighborhood Hits	124
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

EGFL9_MOUSE
NC score	0.212903 (rank : 57)	θ value	8.99809 (rank : 152)
Query Neighborhood Hits	162	Target Neighborhood Hits	379	Shared Neighborhood Hits	127
SwissProt Accessions	Q8K1E3, Q9QYP3	Gene names	Egfl9
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 9 precursor (Multiple EGF-like domain protein 9) (Endothelial cell-specific protein S-1).

JAG2_MOUSE
NC score	0.212671 (rank : 58)	θ value	0.813845 (rank : 103)
Query Neighborhood Hits	162	Target Neighborhood Hits	504	Shared Neighborhood Hits	132
SwissProt Accessions	Q9QYE5, O55139, O70219	Gene names	Jag2
Domain Architecture
Description	Jagged-2 precursor (Jagged2).

JAG2_HUMAN
NC score	0.211645 (rank : 59)	θ value	0.813845 (rank : 102)
Query Neighborhood Hits	162	Target Neighborhood Hits	491	Shared Neighborhood Hits	131
SwissProt Accessions	Q9Y219, Q9UE17, Q9UE99, Q9UNK8, Q9Y6P9, Q9Y6Q0	Gene names	JAG2
Domain Architecture
Description	Jagged-2 precursor (Jagged2) (HJ2).

LTBP3_HUMAN
NC score	0.210713 (rank : 60)	θ value	1.06291 (rank : 109)
Query Neighborhood Hits	162	Target Neighborhood Hits	502	Shared Neighborhood Hits	121
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

NOTC4_MOUSE
NC score	0.209864 (rank : 61)	θ value	0.00390308 (rank : 36)
Query Neighborhood Hits	162	Target Neighborhood Hits	872	Shared Neighborhood Hits	137
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

NRP2_MOUSE
NC score	0.209626 (rank : 62)	θ value	θ > 10 (rank : 362)
Query Neighborhood Hits	162	Target Neighborhood Hits	113	Shared Neighborhood Hits	26
SwissProt Accessions	O35375, O35373, O35374, O35376, O35377, O35378	Gene names	Nrp2
Domain Architecture
Description	Neuropilin-2 precursor (Vascular endothelial cell growth factor 165 receptor 2).

NOTC4_HUMAN
NC score	0.207714 (rank : 63)	θ value	0.0252991 (rank : 50)
Query Neighborhood Hits	162	Target Neighborhood Hits	905	Shared Neighborhood Hits	136
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

LTBP2_HUMAN
NC score	0.205852 (rank : 64)	θ value	2.36792 (rank : 131)
Query Neighborhood Hits	162	Target Neighborhood Hits	552	Shared Neighborhood Hits	130
SwissProt Accessions	Q14767, Q99907, Q9NS51	Gene names	LTBP2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

LTB1S_MOUSE
NC score	0.205544 (rank : 65)	θ value	2.36792 (rank : 130)
Query Neighborhood Hits	162	Target Neighborhood Hits	479	Shared Neighborhood Hits	123
SwissProt Accessions	Q8CG18, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1L_MOUSE
NC score	0.205321 (rank : 66)	θ value	2.36792 (rank : 129)
Query Neighborhood Hits	162	Target Neighborhood Hits	514	Shared Neighborhood Hits	127
SwissProt Accessions	Q8CG19, O88349, Q8BNW7, Q8C7F5, Q8CIR0	Gene names	Ltbp1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTBP4_MOUSE
NC score	0.202780 (rank : 67)	θ value	θ > 10 (rank : 324)
Query Neighborhood Hits	162	Target Neighborhood Hits	607	Shared Neighborhood Hits	121
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

TRAF2_HUMAN
NC score	0.202520 (rank : 68)	θ value	0.000602161 (rank : 28)
Query Neighborhood Hits	162	Target Neighborhood Hits	402	Shared Neighborhood Hits	16
SwissProt Accessions	Q12933, Q96NT2	Gene names	TRAF2, TRAP3
Domain Architecture
Description	TNF receptor-associated factor 2 (Tumor necrosis factor type 2 receptor-associated protein 3).

EGFL8_MOUSE
NC score	0.202270 (rank : 69)	θ value	θ > 10 (rank : 210)
Query Neighborhood Hits	162	Target Neighborhood Hits	266	Shared Neighborhood Hits	118
SwissProt Accessions	Q6GUQ1, O35447	Gene names	Egfl8, Ng3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8).

GAS6_MOUSE
NC score	0.201620 (rank : 70)	θ value	5.27518 (rank : 142)
Query Neighborhood Hits	162	Target Neighborhood Hits	343	Shared Neighborhood Hits	125
SwissProt Accessions	Q61592, Q99K57	Gene names	Gas6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

MDGA1_HUMAN
NC score	0.200381 (rank : 71)	θ value	5.62301e-10 (rank : 13)
Query Neighborhood Hits	162	Target Neighborhood Hits	358	Shared Neighborhood Hits	17
SwissProt Accessions	Q8NFP4, Q8NBE3	Gene names	MDGA1, MAMDC3
Domain Architecture
Description	MAM domain-containing glycosylphosphatidylinositol anchor protein 1 precursor (MAM domain-containing protein 3) (GPI and MAM protein) (Glycosylphosphatidylinositol-MAM) (GPIM).

SCUB3_MOUSE
NC score	0.199855 (rank : 72)	θ value	θ > 10 (rank : 384)
Query Neighborhood Hits	162	Target Neighborhood Hits	442	Shared Neighborhood Hits	116
SwissProt Accessions	Q66PY1, Q68FG9	Gene names	Scube3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

LTB1S_HUMAN
NC score	0.199659 (rank : 73)	θ value	8.99809 (rank : 156)
Query Neighborhood Hits	162	Target Neighborhood Hits	502	Shared Neighborhood Hits	126
SwissProt Accessions	P22064, Q8TD95	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1S precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

LTB1L_HUMAN
NC score	0.199618 (rank : 74)	θ value	8.99809 (rank : 155)
Query Neighborhood Hits	162	Target Neighborhood Hits	553	Shared Neighborhood Hits	126
SwissProt Accessions	Q14766	Gene names	LTBP1
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein, isoform 1L precursor (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1).

SCUB3_HUMAN
NC score	0.199421 (rank : 75)	θ value	θ > 10 (rank : 383)
Query Neighborhood Hits	162	Target Neighborhood Hits	428	Shared Neighborhood Hits	115
SwissProt Accessions	Q8IX30, Q5CZB3, Q86UZ9, Q8NAU9	Gene names	SCUBE3, CEGF3
Domain Architecture	No domain graphic available
Description	Signal peptide, CUB and EGF-like domain-containing protein 3 precursor.

PROZ_MOUSE
NC score	0.199400 (rank : 76)	θ value	0.163984 (rank : 72)
Query Neighborhood Hits	162	Target Neighborhood Hits	410	Shared Neighborhood Hits	132
SwissProt Accessions	Q9CQW3	Gene names	Proz
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

GAS6_HUMAN
NC score	0.199351 (rank : 77)	θ value	θ > 10 (rank : 224)
Query Neighborhood Hits	162	Target Neighborhood Hits	348	Shared Neighborhood Hits	121
SwissProt Accessions	Q14393, Q7Z7N3	Gene names	GAS6
Domain Architecture
Description	Growth-arrest-specific protein 6 precursor (GAS-6).

TRAF2_MOUSE
NC score	0.199152 (rank : 78)	θ value	0.00175202 (rank : 33)
Query Neighborhood Hits	162	Target Neighborhood Hits	394	Shared Neighborhood Hits	14
SwissProt Accessions	P39429, O54896	Gene names	Traf2
Domain Architecture
Description	TNF receptor-associated factor 2.

MEGF6_HUMAN
NC score	0.197378 (rank : 79)	θ value	θ > 10 (rank : 340)
Query Neighborhood Hits	162	Target Neighborhood Hits	671	Shared Neighborhood Hits	128
SwissProt Accessions	O75095, Q5VV39	Gene names	MEGF6, EGFL3, KIAA0815
Domain Architecture	No domain graphic available
Description	Multiple epidermal growth factor-like domains 6 precursor (EGF-like domain-containing protein 3) (Multiple EGF-like domain protein 3).

EGFL8_HUMAN
NC score	0.196745 (rank : 80)	θ value	θ > 10 (rank : 209)
Query Neighborhood Hits	162	Target Neighborhood Hits	270	Shared Neighborhood Hits	116
SwissProt Accessions	Q99944, Q8IV30	Gene names	EGFL8, C6orf8, NG3
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 8 precursor (Epidermal growth factor-like protein 8) (Multiple EGF-like domain protein 8) (Vascular endothelial-statin 2) (VE-statin-2).

EGFL7_MOUSE
NC score	0.196614 (rank : 81)	θ value	θ > 10 (rank : 208)
Query Neighborhood Hits	162	Target Neighborhood Hits	287	Shared Neighborhood Hits	116
SwissProt Accessions	Q9QXT5, Q6XD35, Q9DCP5	Gene names	Egfl7, Megf7
Domain Architecture	No domain graphic available
Description	EGF-like domain-containing protein 7 precursor (Multiple EGF-like domain protein 7) (Multiple epidermal growth factor-like domain protein 7) (Vascular endothelial statin) (VE-statin) (NOTCH4-like protein) (Zneu1).

FBLN5_HUMAN
NC score	0.195900 (rank : 82)	θ value	8.99809 (rank : 154)
Query Neighborhood Hits	162	Target Neighborhood Hits	329	Shared Neighborhood Hits	116
SwissProt Accessions	Q9UBX5, O75966, Q6UWA3	Gene names	FBLN5, DANCE
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance) (Urine p50 protein) (UP50).

C1QR1_HUMAN
NC score	0.195606 (rank : 83)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	162	Target Neighborhood Hits	493	Shared Neighborhood Hits	122
SwissProt Accessions	Q9NPY3, O00274	Gene names	CD93, C1QR1, MXRA4
Domain Architecture
Description	Complement component C1q receptor precursor (Complement component 1 q subcomponent receptor 1) (C1qR) (C1qRp) (C1qR(p)) (C1q/MBL/SPA receptor) (CD93 antigen) (CDw93).

FBLN2_HUMAN
NC score	0.194721 (rank : 84)	θ value	1.06291 (rank : 107)
Query Neighborhood Hits	162	Target Neighborhood Hits	392	Shared Neighborhood Hits	114
SwissProt Accessions	P98095	Gene names	FBLN2
Domain Architecture
Description	Fibulin-2 precursor.

EGF_MOUSE
NC score	0.193866 (rank : 85)	θ value	0.62314 (rank : 94)
Query Neighborhood Hits	162	Target Neighborhood Hits	358	Shared Neighborhood Hits	129
SwissProt Accessions	P01132, Q6P9J2	Gene names	Egf
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor].

FBLN3_MOUSE
NC score	0.193313 (rank : 86)	θ value	0.813845 (rank : 100)
Query Neighborhood Hits	162	Target Neighborhood Hits	279	Shared Neighborhood Hits	113
SwissProt Accessions	Q8BPB5, Q6Y3N6	Gene names	Efemp1, Fbln3
Domain Architecture	No domain graphic available
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3).

FBLN5_MOUSE
NC score	0.192927 (rank : 87)	θ value	θ > 10 (rank : 221)
Query Neighborhood Hits	162	Target Neighborhood Hits	317	Shared Neighborhood Hits	113
SwissProt Accessions	Q9WVH9, Q541Z7	Gene names	Fbln5, Dance
Domain Architecture
Description	Fibulin-5 precursor (FIBL-5) (Developmental arteries and neural crest EGF-like protein) (Dance).

MATN2_HUMAN
NC score	0.191228 (rank : 88)	θ value	0.163984 (rank : 71)
Query Neighborhood Hits	162	Target Neighborhood Hits	365	Shared Neighborhood Hits	108
SwissProt Accessions	O00339, Q6UWA5, Q7Z5X1, Q8NDE6, Q96FT5, Q9NSZ1	Gene names	MATN2
Domain Architecture
Description	Matrilin-2 precursor.

FBLN3_HUMAN
NC score	0.189016 (rank : 89)	θ value	5.27518 (rank : 141)
Query Neighborhood Hits	162	Target Neighborhood Hits	293	Shared Neighborhood Hits	113
SwissProt Accessions	Q12805	Gene names	EFEMP1, FBLN3, FBNL
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 1 precursor (Fibulin-3) (FIBL-3) (Fibrillin-like protein) (Extracellular protein S1-5).

FBLN2_MOUSE
NC score	0.188334 (rank : 90)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	162	Target Neighborhood Hits	505	Shared Neighborhood Hits	115
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

PCOC2_MOUSE
NC score	0.188112 (rank : 91)	θ value	θ > 10 (rank : 370)
Query Neighborhood Hits	162	Target Neighborhood Hits	73	Shared Neighborhood Hits	13
SwissProt Accessions	Q8R4W6, Q3V1K6, Q9CX06	Gene names	Pcolce2, Pcpe2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

MATN2_MOUSE
NC score	0.187789 (rank : 92)	θ value	3.0926 (rank : 133)
Query Neighborhood Hits	162	Target Neighborhood Hits	356	Shared Neighborhood Hits	107
SwissProt Accessions	O08746	Gene names	Matn2
Domain Architecture
Description	Matrilin-2 precursor.

FBLN4_HUMAN
NC score	0.186705 (rank : 93)	θ value	θ > 10 (rank : 219)
Query Neighborhood Hits	162	Target Neighborhood Hits	278	Shared Neighborhood Hits	113
SwissProt Accessions	O95967, O75967	Gene names	EFEMP2, FBLN4
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (UPH1 protein).

PCOC2_HUMAN
NC score	0.186138 (rank : 94)	θ value	θ > 10 (rank : 369)
Query Neighborhood Hits	162	Target Neighborhood Hits	73	Shared Neighborhood Hits	13
SwissProt Accessions	Q9UKZ9, Q9BRH3	Gene names	PCOLCE2, PCPE2
Domain Architecture	No domain graphic available
Description	Procollagen C-endopeptidase enhancer 2 precursor (Procollagen COOH- terminal proteinase enhancer 2) (Procollagen C-proteinase enhancer 2) (PCPE-2).

MAMC1_MOUSE
NC score	0.185751 (rank : 95)	θ value	8.11959e-09 (rank : 14)
Query Neighborhood Hits	162	Target Neighborhood Hits	357	Shared Neighborhood Hits	18
SwissProt Accessions	P60755	Gene names	Mamdc1, Mdga2
Domain Architecture
Description	MAM domain-containing protein 1 precursor (MAM domain-containing glycosylphosphatidylinositol anchor protein 2).

PROZ_HUMAN
NC score	0.185629 (rank : 96)	θ value	6.88961 (rank : 149)
Query Neighborhood Hits	162	Target Neighborhood Hits	422	Shared Neighborhood Hits	129
SwissProt Accessions	P22891, Q15213	Gene names	PROZ
Domain Architecture
Description	Vitamin K-dependent protein Z precursor.

FBLN1_HUMAN
NC score	0.185284 (rank : 97)	θ value	θ > 10 (rank : 216)
Query Neighborhood Hits	162	Target Neighborhood Hits	324	Shared Neighborhood Hits	111
SwissProt Accessions	P23142, P23143, P23144, P37888, Q5TIC4, Q8TBH8, Q9HBQ5, Q9UC21, Q9UGR4, Q9UH41	Gene names	FBLN1
Domain Architecture
Description	Fibulin-1 precursor.

FBLN4_MOUSE
NC score	0.184686 (rank : 98)	θ value	θ > 10 (rank : 220)
Query Neighborhood Hits	162	Target Neighborhood Hits	270	Shared Neighborhood Hits	112
SwissProt Accessions	Q9WVJ9	Gene names	Efemp2, Fbln4, Mbp1
Domain Architecture
Description	EGF-containing fibulin-like extracellular matrix protein 2 precursor (Fibulin-4) (FIBL-4) (Mutant p53-binding protein 1).

PCOC1_MOUSE
NC score	0.184637 (rank : 99)	θ value	θ > 10 (rank : 368)
Query Neighborhood Hits	162	Target Neighborhood Hits	100	Shared Neighborhood Hits	13
SwissProt Accessions	Q61398, O35113	Gene names	Pcolce, Pcpe1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein) (P14).

PCOC1_HUMAN
NC score	0.183996 (rank : 100)	θ value	θ > 10 (rank : 367)
Query Neighborhood Hits	162	Target Neighborhood Hits	146	Shared Neighborhood Hits	13
SwissProt Accessions	Q15113, O14550	Gene names	PCOLCE, PCPE1
Domain Architecture
Description	Procollagen C-endopeptidase enhancer 1 precursor (Procollagen COOH- terminal proteinase enhancer 1) (Procollagen C-proteinase enhancer 1) (PCPE-1) (Type I procollagen COOH-terminal proteinase enhancer) (Type 1 procollagen C-proteinase enhancer protein).

FBLN1_MOUSE
NC score	0.183914 (rank : 101)	θ value	θ > 10 (rank : 217)
Query Neighborhood Hits	162	Target Neighborhood Hits	329	Shared Neighborhood Hits	109
SwissProt Accessions	Q08879, Q08878, Q8C3B1, Q91ZC9, Q922K8	Gene names	Fbln1
Domain Architecture
Description	Fibulin-1 precursor (Basement-membrane protein 90) (BM-90).

ZAN_MOUSE
NC score	0.183838 (rank : 102)	θ value	1.06291 (rank : 113)
Query Neighborhood Hits	162	Target Neighborhood Hits	808	Shared Neighborhood Hits	141
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

MAMC1_HUMAN
NC score	0.183785 (rank : 103)	θ value	1.38499e-08 (rank : 15)
Query Neighborhood Hits	162	Target Neighborhood Hits	357	Shared Neighborhood Hits	18
SwissProt Accessions	Q7Z553	Gene names	MAMDC1, MDGA2
Domain Architecture
Description	MAM domain-containing protein 1 precursor (MAM domain-containing glycosylphosphatidylinositol anchor protein 2).

TRAF1_MOUSE
NC score	0.183769 (rank : 104)	θ value	0.0193708 (rank : 46)
Query Neighborhood Hits	162	Target Neighborhood Hits	52	Shared Neighborhood Hits	13
SwissProt Accessions	P39428	Gene names	Traf1
Domain Architecture
Description	TNF receptor-associated factor 1.

LRP1B_HUMAN
NC score	0.183214 (rank : 105)	θ value	0.0113563 (rank : 41)
Query Neighborhood Hits	162	Target Neighborhood Hits	602	Shared Neighborhood Hits	136
SwissProt Accessions	Q9NZR2, Q8WY29, Q8WY30, Q8WY31	Gene names	LRP1B, LRPDIT
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

TRAF1_HUMAN
NC score	0.182525 (rank : 106)	θ value	0.0193708 (rank : 45)
Query Neighborhood Hits	162	Target Neighborhood Hits	65	Shared Neighborhood Hits	13
SwissProt Accessions	Q13077, Q8NF13	Gene names	TRAF1, EBI6
Domain Architecture
Description	TNF receptor-associated factor 1 (Epstein-Barr virus-induced protein 6).

NID2_MOUSE
NC score	0.182251 (rank : 107)	θ value	1.06291 (rank : 110)
Query Neighborhood Hits	162	Target Neighborhood Hits	338	Shared Neighborhood Hits	120
SwissProt Accessions	O88322	Gene names	Nid2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Entactin-2).

WIF1_MOUSE
NC score	0.181938 (rank : 108)	θ value	8.99809 (rank : 162)
Query Neighborhood Hits	162	Target Neighborhood Hits	393	Shared Neighborhood Hits	118
SwissProt Accessions	Q9WUA1	Gene names	Wif1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

CD97_HUMAN
NC score	0.180720 (rank : 109)	θ value	0.365318 (rank : 86)
Query Neighborhood Hits	162	Target Neighborhood Hits	353	Shared Neighborhood Hits	115
SwissProt Accessions	P48960, O00718, O76101, Q8NG72, Q8TBQ7	Gene names	CD97
Domain Architecture
Description	CD97 antigen precursor (Leukocyte antigen CD97).

NELL2_HUMAN
NC score	0.180533 (rank : 110)	θ value	θ > 10 (rank : 351)
Query Neighborhood Hits	162	Target Neighborhood Hits	449	Shared Neighborhood Hits	125
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

WIF1_HUMAN
NC score	0.180252 (rank : 111)	θ value	6.88961 (rank : 150)
Query Neighborhood Hits	162	Target Neighborhood Hits	392	Shared Neighborhood Hits	120
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

NELL2_MOUSE
NC score	0.179103 (rank : 112)	θ value	θ > 10 (rank : 352)
Query Neighborhood Hits	162	Target Neighborhood Hits	436	Shared Neighborhood Hits	123
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

NID2_HUMAN
NC score	0.179039 (rank : 113)	θ value	4.03905 (rank : 137)
Query Neighborhood Hits	162	Target Neighborhood Hits	456	Shared Neighborhood Hits	122
SwissProt Accessions	Q14112, O43710	Gene names	NID2
Domain Architecture
Description	Nidogen-2 precursor (NID-2) (Osteonidogen).

TRAF6_HUMAN
NC score	0.178401 (rank : 114)	θ value	4.1701e-05 (rank : 24)
Query Neighborhood Hits	162	Target Neighborhood Hits	267	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y4K3, Q8NEH5	Gene names	TRAF6, RNF85
Domain Architecture
Description	TNF receptor-associated factor 6 (Interleukin 1 signal transducer) (RING finger protein 85).

EGF_HUMAN
NC score	0.177771 (rank : 115)	θ value	2.36792 (rank : 128)
Query Neighborhood Hits	162	Target Neighborhood Hits	343	Shared Neighborhood Hits	120
SwissProt Accessions	P01133	Gene names	EGF
Domain Architecture
Description	Pro-epidermal growth factor precursor (EGF) [Contains: Epidermal growth factor (Urogastrone)].

EMR2_HUMAN
NC score	0.177463 (rank : 116)	θ value	1.06291 (rank : 106)
Query Neighborhood Hits	162	Target Neighborhood Hits	345	Shared Neighborhood Hits	115
SwissProt Accessions	Q9UHX3, Q8NG96, Q9Y4B1	Gene names	EMR2
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 2 precursor (EGF-like module EMR2) (CD312 antigen).

MFGM_MOUSE
NC score	0.176303 (rank : 117)	θ value	3.0926 (rank : 134)
Query Neighborhood Hits	162	Target Neighborhood Hits	233	Shared Neighborhood Hits	110
SwissProt Accessions	P21956, P97800, Q3TBN5, Q9R1X9, Q9WTS3	Gene names	Mfge8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (MFGM) (Sperm surface protein SP47) (MP47).

NELL1_HUMAN
NC score	0.175735 (rank : 118)	θ value	θ > 10 (rank : 350)
Query Neighborhood Hits	162	Target Neighborhood Hits	451	Shared Neighborhood Hits	120
SwissProt Accessions	Q92832, Q9Y472	Gene names	NELL1, NRP1
Domain Architecture
Description	Protein kinase C-binding protein NELL1 precursor (NEL-like protein 1) (Nel-related protein 1).

TRBM_HUMAN
NC score	0.175470 (rank : 119)	θ value	θ > 10 (rank : 418)
Query Neighborhood Hits	162	Target Neighborhood Hits	339	Shared Neighborhood Hits	109
SwissProt Accessions	P07204, Q9UC32	Gene names	THBD, THRM
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

LRP1B_MOUSE
NC score	0.174458 (rank : 120)	θ value	0.0961366 (rank : 62)
Query Neighborhood Hits	162	Target Neighborhood Hits	606	Shared Neighborhood Hits	134
SwissProt Accessions	Q9JI18, Q8BZD3, Q8BZM7	Gene names	Lrp1b, Lrpdit
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1B precursor (Low- density lipoprotein receptor-related protein-deleted in tumor) (LRP- DIT).

TRBM_MOUSE
NC score	0.172131 (rank : 121)	θ value	θ > 10 (rank : 419)
Query Neighborhood Hits	162	Target Neighborhood Hits	361	Shared Neighborhood Hits	107
SwissProt Accessions	P15306	Gene names	Thbd
Domain Architecture
Description	Thrombomodulin precursor (TM) (Fetomodulin) (CD141 antigen).

NID1_HUMAN
NC score	0.171878 (rank : 122)	θ value	0.279714 (rank : 83)
Query Neighborhood Hits	162	Target Neighborhood Hits	329	Shared Neighborhood Hits	118
SwissProt Accessions	P14543, Q14942, Q59FL2, Q5TAF2, Q5TAF3, Q86XD7	Gene names	NID1, NID
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

NID1_MOUSE
NC score	0.171555 (rank : 123)	θ value	0.813845 (rank : 104)
Query Neighborhood Hits	162	Target Neighborhood Hits	335	Shared Neighborhood Hits	118
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

SLIT1_MOUSE
NC score	0.171374 (rank : 124)	θ value	0.62314 (rank : 96)
Query Neighborhood Hits	162	Target Neighborhood Hits	715	Shared Neighborhood Hits	136
SwissProt Accessions	Q80TR4, Q9WVB5	Gene names	Slit1, Kiaa0813
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1).

NETO2_HUMAN
NC score	0.170574 (rank : 125)	θ value	θ > 10 (rank : 355)
Query Neighborhood Hits	162	Target Neighborhood Hits	109	Shared Neighborhood Hits	19
SwissProt Accessions	Q8NC67, Q7Z381, Q8ND51, Q96SP4, Q9NVY8	Gene names	NETO2, BTCL2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

SUSD1_HUMAN
NC score	0.170513 (rank : 126)	θ value	θ > 10 (rank : 398)
Query Neighborhood Hits	162	Target Neighborhood Hits	285	Shared Neighborhood Hits	112
SwissProt Accessions	Q6UWL2, Q5T8V7, Q6P9G7, Q8WU83, Q9H6V2, Q9NTA7	Gene names	SUSD1
Domain Architecture	No domain graphic available
Description	Sushi domain-containing protein 1 precursor.

NETO2_MOUSE
NC score	0.170396 (rank : 127)	θ value	θ > 10 (rank : 356)
Query Neighborhood Hits	162	Target Neighborhood Hits	113	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BNJ6, Q5VM49, Q8C4Q8	Gene names	Neto2, Btcl2
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 2 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2).

EMR1_HUMAN
NC score	0.170291 (rank : 128)	θ value	1.81305 (rank : 122)
Query Neighborhood Hits	162	Target Neighborhood Hits	382	Shared Neighborhood Hits	116
SwissProt Accessions	Q14246, Q8NGA7	Gene names	EMR1, TM7LN3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor).

SLIT3_HUMAN
NC score	0.168854 (rank : 129)	θ value	0.0563607 (rank : 56)
Query Neighborhood Hits	162	Target Neighborhood Hits	682	Shared Neighborhood Hits	131
SwissProt Accessions	O75094, O95804, Q9UFH5	Gene names	SLIT3, KIAA0814, MEGF5, SLIL2
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Multiple epidermal growth factor-like domains 5).

NETO1_MOUSE
NC score	0.168842 (rank : 130)	θ value	θ > 10 (rank : 354)
Query Neighborhood Hits	162	Target Neighborhood Hits	109	Shared Neighborhood Hits	22
SwissProt Accessions	Q8R4I7, Q80X39, Q8C4S3, Q8CCM2	Gene names	Neto1, Btcl1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

NETO1_HUMAN
NC score	0.168610 (rank : 131)	θ value	θ > 10 (rank : 353)
Query Neighborhood Hits	162	Target Neighborhood Hits	110	Shared Neighborhood Hits	22
SwissProt Accessions	Q8TDF5, Q86W85, Q8ND78, Q8TDF4	Gene names	NETO1, BTCL1
Domain Architecture	No domain graphic available
Description	Neuropilin and tolloid-like protein 1 precursor (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1).

SLIT2_HUMAN
NC score	0.167113 (rank : 132)	θ value	1.81305 (rank : 124)
Query Neighborhood Hits	162	Target Neighborhood Hits	708	Shared Neighborhood Hits	134
SwissProt Accessions	O94813, O95710, Q9Y5Q7	Gene names	SLIT2, SLIL3
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

PDGFD_MOUSE
NC score	0.166950 (rank : 133)	θ value	θ > 10 (rank : 373)
Query Neighborhood Hits	162	Target Neighborhood Hits	72	Shared Neighborhood Hits	13
SwissProt Accessions	Q925I7, Q3URF6, Q8K2L3, Q9D1L8	Gene names	Pdgfd, Scdgfb
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor chain precursor (PDGF D) (Spinal cord- derived growth factor B) (SCDGF-B).

SLIT1_HUMAN
NC score	0.166911 (rank : 134)	θ value	1.38821 (rank : 119)
Query Neighborhood Hits	162	Target Neighborhood Hits	700	Shared Neighborhood Hits	132
SwissProt Accessions	O75093, Q8WWZ2, Q9UIL7	Gene names	SLIT1, KIAA0813, MEGF4, SLIL1
Domain Architecture
Description	Slit homolog 1 protein precursor (Slit-1) (Multiple epidermal growth factor-like domains 4).

UROM_MOUSE
NC score	0.166453 (rank : 135)	θ value	θ > 10 (rank : 433)
Query Neighborhood Hits	162	Target Neighborhood Hits	276	Shared Neighborhood Hits	118
SwissProt Accessions	Q91X17, Q3TN64, Q3TP60, Q62285	Gene names	Umod
Domain Architecture	No domain graphic available
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

ZAN_HUMAN
NC score	0.165854 (rank : 136)	θ value	0.279714 (rank : 85)
Query Neighborhood Hits	162	Target Neighborhood Hits	679	Shared Neighborhood Hits	134
SwissProt Accessions	Q9Y493, O00218, Q96L85, Q96L86, Q96L87, Q96L88, Q96L89, Q96L90, Q9BXN9, Q9BZ83, Q9BZ84, Q9BZ85, Q9BZ86, Q9BZ87, Q9BZ88	Gene names	ZAN
Domain Architecture
Description	Zonadhesin precursor.

CSPG3_MOUSE
NC score	0.165593 (rank : 137)	θ value	0.21417 (rank : 75)
Query Neighborhood Hits	162	Target Neighborhood Hits	657	Shared Neighborhood Hits	124
SwissProt Accessions	P55066, Q6P1E3, Q8C4F8	Gene names	Cspg3, Ncan
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

MFRP_HUMAN
NC score	0.165120 (rank : 138)	θ value	θ > 10 (rank : 345)
Query Neighborhood Hits	162	Target Neighborhood Hits	165	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BY79, Q335M3, Q96DQ9	Gene names	MFRP
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

CSPG2_MOUSE
NC score	0.164858 (rank : 139)	θ value	0.813845 (rank : 97)
Query Neighborhood Hits	162	Target Neighborhood Hits	711	Shared Neighborhood Hits	124
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

MUC13_MOUSE
NC score	0.164414 (rank : 140)	θ value	0.0330416 (rank : 52)
Query Neighborhood Hits	162	Target Neighborhood Hits	447	Shared Neighborhood Hits	94
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

CSPG3_HUMAN
NC score	0.164410 (rank : 141)	θ value	0.21417 (rank : 74)
Query Neighborhood Hits	162	Target Neighborhood Hits	676	Shared Neighborhood Hits	120
SwissProt Accessions	O14594, Q9UPK6	Gene names	CSPG3, NCAN, NEUR
Domain Architecture
Description	Neurocan core protein precursor (Chondroitin sulfate proteoglycan 3).

CSPG2_HUMAN
NC score	0.164053 (rank : 142)	θ value	0.279714 (rank : 78)
Query Neighborhood Hits	162	Target Neighborhood Hits	681	Shared Neighborhood Hits	122
SwissProt Accessions	P13611, P20754, Q13010, Q13189, Q15123, Q9UCL9, Q9UNW5	Gene names	CSPG2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M) (Glial hyaluronate-binding protein) (GHAP).

SLIT3_MOUSE
NC score	0.163963 (rank : 143)	θ value	0.279714 (rank : 84)
Query Neighborhood Hits	162	Target Neighborhood Hits	700	Shared Neighborhood Hits	130
SwissProt Accessions	Q9WVB4	Gene names	Slit3
Domain Architecture
Description	Slit homolog 3 protein precursor (Slit-3) (Slit3).

SLIT2_MOUSE
NC score	0.163311 (rank : 144)	θ value	1.81305 (rank : 125)
Query Neighborhood Hits	162	Target Neighborhood Hits	684	Shared Neighborhood Hits	130
SwissProt Accessions	Q9R1B9, Q9Z166	Gene names	Slit2
Domain Architecture
Description	Slit homolog 2 protein precursor (Slit-2) [Contains: Slit homolog 2 protein N-product; Slit homolog 2 protein C-product].

TSG6_HUMAN
NC score	0.163003 (rank : 145)	θ value	θ > 10 (rank : 420)
Query Neighborhood Hits	162	Target Neighborhood Hits	91	Shared Neighborhood Hits	21
SwissProt Accessions	P98066, Q8WWI9	Gene names	TNFAIP6, TSG6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein) (Hyaluronate-binding protein).

PDGFD_HUMAN
NC score	0.162912 (rank : 146)	θ value	θ > 10 (rank : 372)
Query Neighborhood Hits	162	Target Neighborhood Hits	74	Shared Neighborhood Hits	13
SwissProt Accessions	Q9GZP0, Q9BWV5	Gene names	PDGFD, IEGF, SCDGFB
Domain Architecture	No domain graphic available
Description	Platelet-derived growth factor D precursor (PDGF D) (Iris-expressed growth factor) (Spinal cord-derived growth factor B) (SCDGF-B).

TSG6_MOUSE
NC score	0.161927 (rank : 147)	θ value	θ > 10 (rank : 421)
Query Neighborhood Hits	162	Target Neighborhood Hits	91	Shared Neighborhood Hits	20
SwissProt Accessions	O08859	Gene names	Tnfaip6, Tnfip6, Tsg6
Domain Architecture
Description	Tumor necrosis factor-inducible protein TSG-6 precursor (TNF- stimulated gene 6 protein).

LRP1_HUMAN
NC score	0.161494 (rank : 148)	θ value	θ > 10 (rank : 315)
Query Neighborhood Hits	162	Target Neighborhood Hits	617	Shared Neighborhood Hits	128
SwissProt Accessions	Q07954, Q2PP12, Q8IVG8	Gene names	LRP1, A2MR
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 1 precursor (LRP) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD91 antigen).

EMR1_MOUSE
NC score	0.160559 (rank : 149)	θ value	4.03905 (rank : 136)
Query Neighborhood Hits	162	Target Neighborhood Hits	349	Shared Neighborhood Hits	113
SwissProt Accessions	Q61549	Gene names	Emr1, Gpf480
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 1 precursor (Cell surface glycoprotein EMR1) (EMR1 hormone receptor) (Cell surface glycoprotein F4/80).

MFRP_MOUSE
NC score	0.160471 (rank : 150)	θ value	θ > 10 (rank : 346)
Query Neighborhood Hits	162	Target Neighborhood Hits	166	Shared Neighborhood Hits	20
SwissProt Accessions	Q8K480, Q8BPP4	Gene names	Mfrp
Domain Architecture	No domain graphic available
Description	Membrane frizzled-related protein (Membrane-type frizzled-related protein).

TRAF3_HUMAN
NC score	0.160313 (rank : 151)	θ value	0.0961366 (rank : 63)
Query Neighborhood Hits	162	Target Neighborhood Hits	463	Shared Neighborhood Hits	15
SwissProt Accessions	Q13114, Q12990, Q13076, Q13947, Q6AZX1, Q9UNL1	Gene names	TRAF3, CAP1, CRAF1
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (CD40-binding protein) (CD40BP) (LMP1-associated protein) (LAP1) (CAP-1).

UROM_HUMAN
NC score	0.160231 (rank : 152)	θ value	θ > 10 (rank : 432)
Query Neighborhood Hits	162	Target Neighborhood Hits	284	Shared Neighborhood Hits	116
SwissProt Accessions	P07911, Q540J6, Q6ZS84, Q8IYG0	Gene names	UMOD
Domain Architecture
Description	Uromodulin precursor (Tamm-Horsfall urinary glycoprotein) (THP).

TRAF3_MOUSE
NC score	0.159845 (rank : 153)	θ value	0.125558 (rank : 67)
Query Neighborhood Hits	162	Target Neighborhood Hits	476	Shared Neighborhood Hits	16
SwissProt Accessions	Q60803, Q62380	Gene names	Traf3, Craf1, Trafamn
Domain Architecture
Description	TNF receptor-associated factor 3 (CD40 receptor-associated factor 1) (CRAF1) (TRAFAMN).

ATRN_HUMAN
NC score	0.159676 (rank : 154)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	162	Target Neighborhood Hits	525	Shared Neighborhood Hits	105
SwissProt Accessions	O75882, O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3, Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, Q9NZ58	Gene names	ATRN, KIAA0548, MGCA
Domain Architecture
Description	Attractin precursor (Mahogany homolog) (DPPT-L).

ATRN_MOUSE
NC score	0.157983 (rank : 155)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	162	Target Neighborhood Hits	519	Shared Neighborhood Hits	106
SwissProt Accessions	Q9WU60, Q9R263, Q9WU77	Gene names	Atrn, mg, Mgca
Domain Architecture
Description	Attractin precursor (Mahogany protein).

TRAF6_MOUSE
NC score	0.155818 (rank : 156)	θ value	0.00228821 (rank : 34)
Query Neighborhood Hits	162	Target Neighborhood Hits	255	Shared Neighborhood Hits	15
SwissProt Accessions	P70196, Q8BLV2	Gene names	Traf6
Domain Architecture
Description	TNF receptor-associated factor 6.

CD248_MOUSE
NC score	0.153928 (rank : 157)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	162	Target Neighborhood Hits	578	Shared Neighborhood Hits	108
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

STAB1_MOUSE
NC score	0.153585 (rank : 158)	θ value	θ > 10 (rank : 396)
Query Neighborhood Hits	162	Target Neighborhood Hits	566	Shared Neighborhood Hits	129
SwissProt Accessions	Q8R4Y4, Q8K0K6, Q8VC09	Gene names	Stab1, Feel1
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein).

AGRIN_HUMAN
NC score	0.153127 (rank : 159)	θ value	2.36792 (rank : 126)
Query Neighborhood Hits	162	Target Neighborhood Hits	582	Shared Neighborhood Hits	124
SwissProt Accessions	O00468, Q5SVA2, Q60FE1, Q7KYS8, Q8N4J5, Q96IC1, Q9BTD4	Gene names	AGRIN, AGRN
Domain Architecture	No domain graphic available
Description	Agrin precursor.

CD248_HUMAN
NC score	0.152921 (rank : 160)	θ value	8.99809 (rank : 151)
Query Neighborhood Hits	162	Target Neighborhood Hits	679	Shared Neighborhood Hits	110
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

MATN4_HUMAN
NC score	0.151370 (rank : 161)	θ value	θ > 10 (rank : 338)
Query Neighborhood Hits	162	Target Neighborhood Hits	287	Shared Neighborhood Hits	103
SwissProt Accessions	O95460, Q5QPU2, Q5QPU3, Q5QPU4, Q8N2M5, Q8N2M7, Q9H1F8, Q9H1F9	Gene names	MATN4
Domain Architecture
Description	Matrilin-4 precursor.

STAB1_HUMAN
NC score	0.150101 (rank : 162)	θ value	θ > 10 (rank : 395)
Query Neighborhood Hits	162	Target Neighborhood Hits	546	Shared Neighborhood Hits	129
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

CSPG5_HUMAN
NC score	0.149840 (rank : 163)	θ value	0.00134147 (rank : 31)
Query Neighborhood Hits	162	Target Neighborhood Hits	199	Shared Neighborhood Hits	28
SwissProt Accessions	O95196, Q71M39, Q71M40	Gene names	CSPG5, CALEB, NGC
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 5 precursor (Neuroglycan C) (Acidic leucine-rich EGF-like domain-containing brain protein).

CUZD1_HUMAN
NC score	0.149228 (rank : 164)	θ value	θ > 10 (rank : 199)
Query Neighborhood Hits	162	Target Neighborhood Hits	89	Shared Neighborhood Hits	13
SwissProt Accessions	Q86UP6, Q7Z660, Q7Z661, Q86SG1, Q86UP5, Q9HAR7	Gene names	CUZD1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Transmembrane protein UO-44).

TSP4_MOUSE
NC score	0.149074 (rank : 165)	θ value	θ > 10 (rank : 429)
Query Neighborhood Hits	162	Target Neighborhood Hits	276	Shared Neighborhood Hits	115
SwissProt Accessions	Q9Z1T2, Q9QYS3, Q9WUE0	Gene names	Thbs4, Tsp4
Domain Architecture
Description	Thrombospondin-4 precursor.

LRP8_HUMAN
NC score	0.148578 (rank : 166)	θ value	1.06291 (rank : 108)
Query Neighborhood Hits	162	Target Neighborhood Hits	346	Shared Neighborhood Hits	108
SwissProt Accessions	Q14114, O14968, Q86V27, Q99876, Q9BR78	Gene names	LRP8, APOER2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

CREL1_HUMAN
NC score	0.146827 (rank : 167)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	162	Target Neighborhood Hits	441	Shared Neighborhood Hits	105
SwissProt Accessions	Q96HD1, Q6I9X5, Q8NFT4, Q9Y409	Gene names	CRELD1, CIRRIN
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

TSP4_HUMAN
NC score	0.146423 (rank : 168)	θ value	θ > 10 (rank : 428)
Query Neighborhood Hits	162	Target Neighborhood Hits	277	Shared Neighborhood Hits	115
SwissProt Accessions	P35443, Q86TG2	Gene names	THBS4, TSP4
Domain Architecture
Description	Thrombospondin-4 precursor.

DMBT1_MOUSE
NC score	0.145771 (rank : 169)	θ value	θ > 10 (rank : 206)
Query Neighborhood Hits	162	Target Neighborhood Hits	134	Shared Neighborhood Hits	13
SwissProt Accessions	Q60997, Q80YC6, Q9JMJ9	Gene names	Dmbt1, Crpd
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (CRP-ductin) (Vomeroglandin).

ENTK_HUMAN
NC score	0.145723 (rank : 170)	θ value	1.17247e-07 (rank : 16)
Query Neighborhood Hits	162	Target Neighborhood Hits	310	Shared Neighborhood Hits	43
SwissProt Accessions	P98073	Gene names	PRSS7, ENTK
Domain Architecture
Description	Enteropeptidase precursor (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

ENTK_MOUSE
NC score	0.145550 (rank : 171)	θ value	4.1701e-05 (rank : 23)
Query Neighborhood Hits	162	Target Neighborhood Hits	338	Shared Neighborhood Hits	45
SwissProt Accessions	P97435	Gene names	Prss7, Entk
Domain Architecture
Description	Enteropeptidase (EC 3.4.21.9) (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain].

STAB2_HUMAN
NC score	0.144924 (rank : 172)	θ value	8.99809 (rank : 159)
Query Neighborhood Hits	162	Target Neighborhood Hits	534	Shared Neighborhood Hits	123
SwissProt Accessions	Q8WWQ8, Q6ZMK2, Q7Z5N9, Q86UR4, Q8IUG9, Q8TES1, Q9H7H7, Q9NRY3	Gene names	STAB2, FEEL2, FELL, FEX2, HARE
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor (FEEL-2 protein) (Fasciclin EGF-like laminin-type EGF-like and link domain-containing scavenger receptor 1) (FAS1 EGF- like and X-link domain-containing adhesion molecule 2) (Hyaluronan receptor for endocytosis) [Contains: 190 kDa form stabilin-2 (190 kDa hyaluronan receptor for endocytosis)].

CUZD1_MOUSE
NC score	0.144873 (rank : 173)	θ value	θ > 10 (rank : 200)
Query Neighborhood Hits	162	Target Neighborhood Hits	91	Shared Neighborhood Hits	13
SwissProt Accessions	P70412, Q9CTZ7	Gene names	Cuzd1, Itmap1
Domain Architecture	No domain graphic available
Description	CUB and zona pellucida-like domain-containing protein 1 precursor (Integral membrane-associated protein 1).

LRP12_MOUSE
NC score	0.144440 (rank : 174)	θ value	θ > 10 (rank : 314)
Query Neighborhood Hits	162	Target Neighborhood Hits	180	Shared Neighborhood Hits	37
SwissProt Accessions	Q8BUJ9, Q8BWM9	Gene names	Lrp12
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor.

LRP2_HUMAN
NC score	0.144130 (rank : 175)	θ value	θ > 10 (rank : 316)
Query Neighborhood Hits	162	Target Neighborhood Hits	573	Shared Neighborhood Hits	124
SwissProt Accessions	P98164, O00711, Q16215	Gene names	LRP2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330).

LDLR_HUMAN
NC score	0.144077 (rank : 176)	θ value	θ > 10 (rank : 309)
Query Neighborhood Hits	162	Target Neighborhood Hits	375	Shared Neighborhood Hits	108
SwissProt Accessions	P01130, Q53ZD9	Gene names	LDLR
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

LRP8_MOUSE
NC score	0.144064 (rank : 177)	θ value	6.88961 (rank : 148)
Query Neighborhood Hits	162	Target Neighborhood Hits	385	Shared Neighborhood Hits	108
SwissProt Accessions	Q924X6, Q8CAK9, Q8CDF5, Q921B6	Gene names	Lrp8, Apoer2
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 8 precursor (Apolipoprotein E receptor 2).

LRP12_HUMAN
NC score	0.143878 (rank : 178)	θ value	θ > 10 (rank : 313)
Query Neighborhood Hits	162	Target Neighborhood Hits	205	Shared Neighborhood Hits	38
SwissProt Accessions	Q9Y561	Gene names	LRP12, ST7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 12 precursor (Suppressor of tumorigenicity protein 7).

MUC13_HUMAN
NC score	0.141653 (rank : 179)	θ value	0.0148317 (rank : 43)
Query Neighborhood Hits	162	Target Neighborhood Hits	164	Shared Neighborhood Hits	68
SwissProt Accessions	Q9H3R2, Q6UWD9, Q9NXT5	Gene names	MUC13, DRCC1, RECC
Domain Architecture	No domain graphic available
Description	Mucin-13 precursor (Down-regulated in colon cancer 1).

STAB2_MOUSE
NC score	0.141576 (rank : 180)	θ value	θ > 10 (rank : 397)
Query Neighborhood Hits	162	Target Neighborhood Hits	528	Shared Neighborhood Hits	122
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

CREL1_MOUSE
NC score	0.141248 (rank : 181)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	162	Target Neighborhood Hits	524	Shared Neighborhood Hits	106
SwissProt Accessions	Q91XD7, Q8BGJ8	Gene names	Creld1
Domain Architecture	No domain graphic available
Description	Cysteine-rich with EGF-like domain protein 1 precursor.

VLDLR_MOUSE
NC score	0.141031 (rank : 182)	θ value	8.99809 (rank : 161)
Query Neighborhood Hits	162	Target Neighborhood Hits	360	Shared Neighborhood Hits	108
SwissProt Accessions	P98156, Q64022	Gene names	Vldlr
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

MATN3_MOUSE
NC score	0.140423 (rank : 183)	θ value	θ > 10 (rank : 337)
Query Neighborhood Hits	162	Target Neighborhood Hits	261	Shared Neighborhood Hits	95
SwissProt Accessions	O35701, Q9JHM0	Gene names	Matn3
Domain Architecture
Description	Matrilin-3 precursor.

VLDLR_HUMAN
NC score	0.140421 (rank : 184)	θ value	8.99809 (rank : 160)
Query Neighborhood Hits	162	Target Neighborhood Hits	383	Shared Neighborhood Hits	109
SwissProt Accessions	P98155, Q5VVF6	Gene names	VLDLR
Domain Architecture
Description	Very low-density lipoprotein receptor precursor (VLDL receptor) (VLDL- R).

MATN3_HUMAN
NC score	0.140169 (rank : 185)	θ value	θ > 10 (rank : 336)
Query Neighborhood Hits	162	Target Neighborhood Hits	268	Shared Neighborhood Hits	97
SwissProt Accessions	O15232	Gene names	MATN3
Domain Architecture
Description	Matrilin-3 precursor.

SREC_HUMAN
NC score	0.139391 (rank : 186)	θ value	θ > 10 (rank : 391)
Query Neighborhood Hits	162	Target Neighborhood Hits	645	Shared Neighborhood Hits	113
SwissProt Accessions	Q14162, O43701	Gene names	SCARF1, KIAA0149, SREC
Domain Architecture	No domain graphic available
Description	Endothelial cells scavenger receptor precursor (Acetyl LDL receptor) (Scavenger receptor class F member 1).

MFGM_HUMAN
NC score	0.139277 (rank : 187)	θ value	1.38821 (rank : 116)
Query Neighborhood Hits	162	Target Neighborhood Hits	150	Shared Neighborhood Hits	96
SwissProt Accessions	Q08431	Gene names	MFGE8
Domain Architecture
Description	Lactadherin precursor (Milk fat globule-EGF factor 8) (MFG-E8) (HMFG) (Breast epithelial antigen BA46) (MFGM) [Contains: Lactadherin short form; Medin].

TRAF5_MOUSE
NC score	0.139181 (rank : 188)	θ value	θ > 10 (rank : 417)
Query Neighborhood Hits	162	Target Neighborhood Hits	355	Shared Neighborhood Hits	13
SwissProt Accessions	P70191, Q61480	Gene names	Traf5
Domain Architecture
Description	TNF receptor-associated factor 5.

CD97_MOUSE
NC score	0.138892 (rank : 189)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	162	Target Neighborhood Hits	295	Shared Neighborhood Hits	106
SwissProt Accessions	Q9Z0M6, Q923A1, Q9CVI5, Q9JLQ8	Gene names	Cd97
Domain Architecture
Description	CD97 antigen precursor.

CSMD2_HUMAN
NC score	0.138355 (rank : 190)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	162	Target Neighborhood Hits	188	Shared Neighborhood Hits	30
SwissProt Accessions	Q7Z408, Q5VT59, Q8N963, Q96Q03, Q9H4V7, Q9H4V8, Q9H4V9, Q9H4W0, Q9H4W1, Q9H4W2, Q9H4W3, Q9H4W4, Q9HCY5, Q9HCY6, Q9HCY7	Gene names	CSMD2, KIAA1884
Domain Architecture
Description	CUB and sushi domain-containing protein 2 (CUB and sushi multiple domains protein 2).

SEZ6L_HUMAN
NC score	0.138275 (rank : 191)	θ value	θ > 10 (rank : 385)
Query Neighborhood Hits	162	Target Neighborhood Hits	289	Shared Neighborhood Hits	20
SwissProt Accessions	Q9BYH1, O95917, Q5THY5, Q6IBZ4, Q6UXD4, Q9NUI3, Q9NUI4, Q9NUI5, Q9Y2E1, Q9Y3J6	Gene names	SEZ6L, KIAA0927
Domain Architecture
Description	Seizure 6-like protein precursor.

HABP2_MOUSE
NC score	0.137435 (rank : 192)	θ value	0.000786445 (rank : 29)
Query Neighborhood Hits	162	Target Neighborhood Hits	445	Shared Neighborhood Hits	121
SwissProt Accessions	Q8K0D2	Gene names	Habp2, Phbp
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

MATN4_MOUSE
NC score	0.136629 (rank : 193)	θ value	θ > 10 (rank : 339)
Query Neighborhood Hits	162	Target Neighborhood Hits	277	Shared Neighborhood Hits	97
SwissProt Accessions	O89029, O89030, Q9QWS3	Gene names	Matn4
Domain Architecture
Description	Matrilin-4 precursor (MAT-4).

CSMD1_HUMAN
NC score	0.136461 (rank : 194)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	162	Target Neighborhood Hits	176	Shared Neighborhood Hits	30
SwissProt Accessions	Q96PZ7, Q96QU9, Q96RM4	Gene names	CSMD1, KIAA1890
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

LDLR_MOUSE
NC score	0.136246 (rank : 195)	θ value	θ > 10 (rank : 310)
Query Neighborhood Hits	162	Target Neighborhood Hits	382	Shared Neighborhood Hits	104
SwissProt Accessions	P35951	Gene names	Ldlr
Domain Architecture
Description	Low-density lipoprotein receptor precursor (LDL receptor).

CSMD3_HUMAN
NC score	0.135662 (rank : 196)	θ value	θ > 10 (rank : 198)
Query Neighborhood Hits	162	Target Neighborhood Hits	199	Shared Neighborhood Hits	36
SwissProt Accessions	Q7Z407, Q96PZ3	Gene names	CSMD3, KIAA1894
Domain Architecture
Description	CUB and sushi domain-containing protein 3 precursor (CUB and sushi multiple domains protein 3).

SREC2_MOUSE
NC score	0.135061 (rank : 197)	θ value	θ > 10 (rank : 390)
Query Neighborhood Hits	162	Target Neighborhood Hits	605	Shared Neighborhood Hits	111
SwissProt Accessions	P59222	Gene names	Scarf2, Srec2
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II).

SREC2_HUMAN
NC score	0.134678 (rank : 198)	θ value	θ > 10 (rank : 389)
Query Neighborhood Hits	162	Target Neighborhood Hits	645	Shared Neighborhood Hits	109
SwissProt Accessions	Q96GP6, Q8IXF3, Q9BW74	Gene names	SCARF2, SREC2, SREPCR
Domain Architecture	No domain graphic available
Description	Scavenger receptor class F member 2 precursor (Scavenger receptor expressed by endothelial cells 2 protein) (SREC-II) (SRECRP-1).

CSPG5_MOUSE
NC score	0.134551 (rank : 199)	θ value	0.00509761 (rank : 37)
Query Neighborhood Hits	162	Target Neighborhood Hits	211	Shared Neighborhood Hits	19
SwissProt Accessions	Q71M36, Q71M37, Q7TNT8, Q8BPJ5, Q9QY32	Gene names	Cspg5, Caleb, Ngc
Domain Architecture	No domain graphic available
Description	Chondroitin sulfate proteoglycan 5 precursor (Neuroglycan C) (Acidic leucine-rich EGF-like domain-containing brain protein).

CSMD1_MOUSE
NC score	0.134001 (rank : 200)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	162	Target Neighborhood Hits	193	Shared Neighborhood Hits	32
SwissProt Accessions	Q923L3, Q8BUV1, Q8BYQ3	Gene names	Csmd1
Domain Architecture
Description	CUB and sushi domain-containing protein 1 precursor (CUB and sushi multiple domains protein 1).

TSP3_MOUSE
NC score	0.133190 (rank : 201)	θ value	θ > 10 (rank : 427)
Query Neighborhood Hits	162	Target Neighborhood Hits	247	Shared Neighborhood Hits	108
SwissProt Accessions	Q05895, Q6LCE0	Gene names	Thbs3, Tsp3
Domain Architecture
Description	Thrombospondin-3 precursor.

FATH_HUMAN
NC score	0.133006 (rank : 202)	θ value	0.0563607 (rank : 54)
Query Neighborhood Hits	162	Target Neighborhood Hits	570	Shared Neighborhood Hits	128
SwissProt Accessions	Q14517	Gene names	FAT
Domain Architecture
Description	Cadherin-related tumor suppressor homolog precursor (Protein fat homolog).

TSP3_HUMAN
NC score	0.132796 (rank : 203)	θ value	θ > 10 (rank : 426)
Query Neighborhood Hits	162	Target Neighborhood Hits	250	Shared Neighborhood Hits	110
SwissProt Accessions	P49746, Q8WV34	Gene names	THBS3, TSP3
Domain Architecture
Description	Thrombospondin-3 precursor.

HABP2_HUMAN
NC score	0.131105 (rank : 204)	θ value	0.0252991 (rank : 49)
Query Neighborhood Hits	162	Target Neighborhood Hits	431	Shared Neighborhood Hits	118
SwissProt Accessions	Q14520, O00663	Gene names	HABP2, HGFAL, PHBP
Domain Architecture	No domain graphic available
Description	Hyaluronan-binding protein 2 precursor (EC 3.4.21.-) (Plasma hyaluronan-binding protein) (Hepatocyte growth factor activator-like protein) (Factor VII-activating protease) (Factor seven-activating protease) (FSAP) [Contains: Hyaluronan-binding protein 2 50 kDa heavy chain; Hyaluronan-binding protein 2 50 kDa heavy chain alternate form; Hyaluronan-binding protein 2 27 kDa light chain; Hyaluronan-binding protein 2 27 kDa light chain alternate form].

TRAF5_HUMAN
NC score	0.130625 (rank : 205)	θ value	θ > 10 (rank : 416)
Query Neighborhood Hits	162	Target Neighborhood Hits	396	Shared Neighborhood Hits	14
SwissProt Accessions	O00463	Gene names	TRAF5, RNF84
Domain Architecture
Description	TNF receptor-associated factor 5 (RING finger protein 84).

DCBD2_HUMAN
NC score	0.130064 (rank : 206)	θ value	θ > 10 (rank : 203)
Query Neighborhood Hits	162	Target Neighborhood Hits	118	Shared Neighborhood Hits	18
SwissProt Accessions	Q96PD2, Q8N6M4, Q8TDX2	Gene names	DCBLD2, CLCP1, ESDN
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein) (CUB, LCCL and coagulation factor V/VIII-homology domains protein 1).

ELTD1_MOUSE
NC score	0.129469 (rank : 207)	θ value	θ > 10 (rank : 212)
Query Neighborhood Hits	162	Target Neighborhood Hits	288	Shared Neighborhood Hits	110
SwissProt Accessions	Q923X1, Q91W44	Gene names	Eltd1
Domain Architecture
Description	EGF, latrophilin seven transmembrane domain-containing protein 1 precursor.

C1RA_MOUSE
NC score	0.128653 (rank : 208)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	162	Target Neighborhood Hits	379	Shared Neighborhood Hits	90
SwissProt Accessions	Q8CG16, Q99KI6, Q9ET60	Gene names	C1ra, C1r
Domain Architecture
Description	Complement C1r-A subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-A subcomponent) [Contains: Complement C1r-A subcomponent heavy chain; Complement C1r-A subcomponent light chain].

DCBD2_MOUSE
NC score	0.128028 (rank : 209)	θ value	θ > 10 (rank : 204)
Query Neighborhood Hits	162	Target Neighborhood Hits	113	Shared Neighborhood Hits	18
SwissProt Accessions	Q91ZV3, Q8BKI4	Gene names	Dcbld2, Esdn
Domain Architecture
Description	Discoidin, CUB and LCCL domain-containing protein 2 precursor (Endothelial and smooth muscle cell-derived neuropilin-like protein).

LRP4_MOUSE
NC score	0.127483 (rank : 210)	θ value	θ > 10 (rank : 319)
Query Neighborhood Hits	162	Target Neighborhood Hits	351	Shared Neighborhood Hits	100
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

HMCN1_HUMAN
NC score	0.127147 (rank : 211)	θ value	θ > 10 (rank : 230)
Query Neighborhood Hits	162	Target Neighborhood Hits	983	Shared Neighborhood Hits	119
SwissProt Accessions	Q96RW7, Q5TYR7, Q96DN3, Q96DN8, Q96SC3	Gene names	HMCN1, FIBL6
Domain Architecture	No domain graphic available
Description	Hemicentin-1 precursor (Fibulin-6) (FIBL-6).

C1RB_MOUSE
NC score	0.126763 (rank : 212)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	162	Target Neighborhood Hits	380	Shared Neighborhood Hits	89
SwissProt Accessions	Q8CFG9	Gene names	C1rb, C1r
Domain Architecture	No domain graphic available
Description	Complement C1r-B subcomponent precursor (EC 3.4.21.41) (Complement component 1, r-B subcomponent) [Contains: Complement C1r-B subcomponent heavy chain; Complement C1r-B subcomponent light chain].

LRP4_HUMAN
NC score	0.126393 (rank : 213)	θ value	θ > 10 (rank : 318)
Query Neighborhood Hits	162	Target Neighborhood Hits	355	Shared Neighborhood Hits	102
SwissProt Accessions	O75096	Gene names	LRP4, KIAA0816, MEGF7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (Multiple epidermal growth factor-like domains 7).

C1R_HUMAN
NC score	0.126285 (rank : 214)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	162	Target Neighborhood Hits	364	Shared Neighborhood Hits	80
SwissProt Accessions	P00736, Q8J012	Gene names	C1R
Domain Architecture
Description	Complement C1r subcomponent precursor (EC 3.4.21.41) (Complement component 1, r subcomponent) [Contains: Complement C1r subcomponent heavy chain; Complement C1r subcomponent light chain].

MEGF8_HUMAN
NC score	0.126186 (rank : 215)	θ value	θ > 10 (rank : 341)
Query Neighborhood Hits	162	Target Neighborhood Hits	528	Shared Neighborhood Hits	115
SwissProt Accessions	Q7Z7M0, O75097	Gene names	MEGF8, EGFL4, KIAA0817
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

CS1B_MOUSE
NC score	0.125907 (rank : 216)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	162	Target Neighborhood Hits	361	Shared Neighborhood Hits	86
SwissProt Accessions	Q8CFG8	Gene names	C1sb, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-B subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-B subcomponent heavy chain; Complement C1s-B subcomponent light chain].

MEGF8_MOUSE
NC score	0.125860 (rank : 217)	θ value	θ > 10 (rank : 342)
Query Neighborhood Hits	162	Target Neighborhood Hits	520	Shared Neighborhood Hits	114
SwissProt Accessions	P60882, Q80TR3, Q80V41, Q8BMN9, Q8JZW7, Q8K0J3	Gene names	Megf8, Egfl4
Domain Architecture
Description	Multiple epidermal growth factor-like domains 8 (EGF-like domain- containing protein 4) (Multiple EGF-like domain protein 4).

CS1A_MOUSE
NC score	0.125851 (rank : 218)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	162	Target Neighborhood Hits	360	Shared Neighborhood Hits	86
SwissProt Accessions	Q8CG14, Q8BJC4, Q8CH28, Q8VBY4	Gene names	C1sa, C1s
Domain Architecture	No domain graphic available
Description	Complement C1s-A subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s-A subcomponent heavy chain; Complement C1s-A subcomponent light chain].

COMP_MOUSE
NC score	0.124595 (rank : 219)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	162	Target Neighborhood Hits	290	Shared Neighborhood Hits	104
SwissProt Accessions	Q9R0G6	Gene names	Comp
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

FA10_HUMAN
NC score	0.123796 (rank : 220)	θ value	0.0961366 (rank : 59)
Query Neighborhood Hits	162	Target Neighborhood Hits	431	Shared Neighborhood Hits	131
SwissProt Accessions	P00742, Q14340	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) (Stuart- Prower factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

MASP1_HUMAN
NC score	0.122708 (rank : 221)	θ value	θ > 10 (rank : 330)
Query Neighborhood Hits	162	Target Neighborhood Hits	369	Shared Neighborhood Hits	77
SwissProt Accessions	P48740, O95570, Q9UF09	Gene names	MASP1, CRARF, CRARF1, PRSS5
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) (Mannose-binding protein- associated serine protease) (MASP-1) [Contains: Complement-activating component of Ra-reactive factor heavy chain; Complement-activating component of Ra-reactive factor light chain].

C1S_HUMAN
NC score	0.122581 (rank : 222)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	162	Target Neighborhood Hits	359	Shared Neighborhood Hits	89
SwissProt Accessions	P09871, Q9UCU7, Q9UCU8, Q9UCU9, Q9UCV0, Q9UCV1, Q9UCV2, Q9UCV3, Q9UCV4, Q9UCV5, Q9UM14	Gene names	C1S
Domain Architecture
Description	Complement C1s subcomponent precursor (EC 3.4.21.42) (C1 esterase) [Contains: Complement C1s subcomponent heavy chain; Complement C1s subcomponent light chain].

MASP2_MOUSE
NC score	0.122236 (rank : 223)	θ value	θ > 10 (rank : 333)
Query Neighborhood Hits	162	Target Neighborhood Hits	382	Shared Neighborhood Hits	84
SwissProt Accessions	Q91WP0, Q9QXA4, Q9QXD2, Q9QXD5, Q9Z338	Gene names	Masp2
Domain Architecture	No domain graphic available
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

TENA_HUMAN
NC score	0.122001 (rank : 224)	θ value	θ > 10 (rank : 405)
Query Neighborhood Hits	162	Target Neighborhood Hits	631	Shared Neighborhood Hits	116
SwissProt Accessions	P24821, Q14583, Q15567	Gene names	TNC, HXB
Domain Architecture
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion) (Cytotactin) (Neuronectin) (GMEM) (JI) (Myotendinous antigen) (Glioma- associated-extracellular matrix antigen) (GP 150-225).

MASP2_HUMAN
NC score	0.121909 (rank : 225)	θ value	θ > 10 (rank : 332)
Query Neighborhood Hits	162	Target Neighborhood Hits	364	Shared Neighborhood Hits	77
SwissProt Accessions	O00187, O75754, Q5TEQ5, Q5TER0, Q96QG4, Q9BZH0, Q9H498, Q9H499, Q9UBP3, Q9ULC7, Q9UMV3, Q9Y270	Gene names	MASP2
Domain Architecture
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

FA10_MOUSE
NC score	0.121622 (rank : 226)	θ value	0.279714 (rank : 82)
Query Neighborhood Hits	162	Target Neighborhood Hits	435	Shared Neighborhood Hits	132
SwissProt Accessions	O88947, O54740, Q99L32	Gene names	F10
Domain Architecture
Description	Coagulation factor X precursor (EC 3.4.21.6) (Stuart factor) [Contains: Factor X light chain; Factor X heavy chain; Activated factor Xa heavy chain].

TENX_HUMAN
NC score	0.121127 (rank : 227)	θ value	θ > 10 (rank : 411)
Query Neighborhood Hits	162	Target Neighborhood Hits	789	Shared Neighborhood Hits	116
SwissProt Accessions	P22105, P78530, P78531, Q08424, Q9UMG7	Gene names	TNXB, HXBL, TNX, XB
Domain Architecture
Description	Tenascin-X precursor (TN-X) (Hexabrachion-like protein).

MASP1_MOUSE
NC score	0.120510 (rank : 228)	θ value	θ > 10 (rank : 331)
Query Neighborhood Hits	162	Target Neighborhood Hits	364	Shared Neighborhood Hits	78
SwissProt Accessions	P98064	Gene names	Masp1, Crarf
Domain Architecture
Description	Complement-activating component of Ra-reactive factor precursor (EC 3.4.21.-) (Ra-reactive factor serine protease p100) (RaRF) (Mannan-binding lectin serine protease 1) [Contains: Complement- activating component of Ra-reactive factor heavy chain; Complement- activating component of Ra-reactive factor light chain].

LRP3_HUMAN
NC score	0.119909 (rank : 229)	θ value	θ > 10 (rank : 317)
Query Neighborhood Hits	162	Target Neighborhood Hits	280	Shared Neighborhood Hits	53
SwissProt Accessions	O75074	Gene names	LRP3
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 3 precursor (hLRp105).

TENA_MOUSE
NC score	0.119670 (rank : 230)	θ value	θ > 10 (rank : 406)
Query Neighborhood Hits	162	Target Neighborhood Hits	596	Shared Neighborhood Hits	111
SwissProt Accessions	Q80YX1, Q64706, Q80YX2	Gene names	Tnc, Hxb
Domain Architecture	No domain graphic available
Description	Tenascin precursor (TN) (Tenascin-C) (TN-C) (Hexabrachion).

PGH2_MOUSE
NC score	0.119453 (rank : 231)	θ value	0.62314 (rank : 95)
Query Neighborhood Hits	162	Target Neighborhood Hits	113	Shared Neighborhood Hits	81
SwissProt Accessions	Q05769	Gene names	Ptgs2, Cox-2, Cox2, Pghs-b, Tis10
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II) (Glucocorticoid- regulated inflammatory cyclooxygenase) (Gripghs) (TIS10 protein) (Macrophage activation-associated marker protein P71/73) (PES-2).

DCBD1_HUMAN
NC score	0.117240 (rank : 232)	θ value	θ > 10 (rank : 201)
Query Neighborhood Hits	162	Target Neighborhood Hits	110	Shared Neighborhood Hits	18
SwissProt Accessions	Q8N8Z6, Q5H992, Q8IYK5, Q8N7L9, Q96NH2	Gene names	DCBLD1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

DMBT1_HUMAN
NC score	0.117098 (rank : 233)	θ value	θ > 10 (rank : 205)
Query Neighborhood Hits	162	Target Neighborhood Hits	152	Shared Neighborhood Hits	16
SwissProt Accessions	Q9UGM3, Q59EX0, Q5JR26, Q6MZN4, Q96DU4, Q9UGM2, Q9UJ57, Q9UKJ4, Q9Y211, Q9Y4V9	Gene names	DMBT1, GP340
Domain Architecture	No domain graphic available
Description	Deleted in malignant brain tumors 1 protein precursor (Glycoprotein 340) (Gp-340) (Surfactant pulmonary-associated D-binding protein).

PGH2_HUMAN
NC score	0.116985 (rank : 234)	θ value	0.125558 (rank : 66)
Query Neighborhood Hits	162	Target Neighborhood Hits	103	Shared Neighborhood Hits	73
SwissProt Accessions	P35354, Q16876	Gene names	PTGS2, COX2
Domain Architecture
Description	Prostaglandin G/H synthase 2 precursor (EC 1.14.99.1) (Cyclooxygenase- 2) (COX-2) (Prostaglandin-endoperoxide synthase 2) (Prostaglandin H2 synthase 2) (PGH synthase 2) (PGHS-2) (PHS II).

COMP_HUMAN
NC score	0.116152 (rank : 235)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	162	Target Neighborhood Hits	258	Shared Neighborhood Hits	101
SwissProt Accessions	P49747, O14592, Q16388, Q16389, Q8N4T2	Gene names	COMP
Domain Architecture
Description	Cartilage oligomeric matrix protein precursor (COMP).

FA9_HUMAN
NC score	0.115482 (rank : 236)	θ value	0.813845 (rank : 99)
Query Neighborhood Hits	162	Target Neighborhood Hits	421	Shared Neighborhood Hits	131
SwissProt Accessions	P00740	Gene names	F9
Domain Architecture
Description	Coagulation factor IX precursor (EC 3.4.21.22) (Christmas factor) (Plasma thromboplastin component) (PTC) [Contains: Coagulation factor IXa light chain; Coagulation factor IXa heavy chain].

KR107_HUMAN
NC score	0.114512 (rank : 237)	θ value	θ > 10 (rank : 251)
Query Neighborhood Hits	162	Target Neighborhood Hits	330	Shared Neighborhood Hits	79
SwissProt Accessions	P60409, Q70LJ2	Gene names	KRTAP10-7, KAP10.7, KAP18-7, KRTAP10.7, KRTAP18-7, KRTAP18.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-7 (Keratin-associated protein 10.7) (High sulfur keratin-associated protein 10.7) (Keratin-associated protein 18-7) (Keratin-associated protein 18.7).

KR106_HUMAN
NC score	0.113326 (rank : 238)	θ value	θ > 10 (rank : 250)
Query Neighborhood Hits	162	Target Neighborhood Hits	347	Shared Neighborhood Hits	78
SwissProt Accessions	P60371	Gene names	KRTAP10-6, KAP10.6, KAP18-6, KRTAP10.6, KRTAP18-6, KRTAP18.6
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-6 (Keratin-associated protein 10.6) (High sulfur keratin-associated protein 10.6) (Keratin-associated protein 18-6) (Keratin-associated protein 18.6).

CELR2_HUMAN
NC score	0.113262 (rank : 239)	θ value	0.21417 (rank : 73)
Query Neighborhood Hits	162	Target Neighborhood Hits	657	Shared Neighborhood Hits	132
SwissProt Accessions	Q9HCU4, Q92566	Gene names	CELSR2, CDHF10, EGFL2, KIAA0279, MEGF3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Epidermal growth factor-like 2) (Multiple epidermal growth factor-like domains 3) (Flamingo 1).

CELR3_HUMAN
NC score	0.113138 (rank : 240)	θ value	0.365318 (rank : 88)
Query Neighborhood Hits	162	Target Neighborhood Hits	680	Shared Neighborhood Hits	130
SwissProt Accessions	Q9NYQ7, O75092	Gene names	CELSR3, CDHF11, EGFL1, FMI1, KIAA0812, MEGF2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor (Flamingo homolog 1) (hFmi1) (Multiple epidermal growth factor-like domains 2) (Epidermal growth factor-like 1).

HHIP_HUMAN
NC score	0.112888 (rank : 241)	θ value	θ > 10 (rank : 228)
Query Neighborhood Hits	162	Target Neighborhood Hits	249	Shared Neighborhood Hits	76
SwissProt Accessions	Q96QV1, Q6PK09, Q8NCI7, Q9BXK3, Q9H1J4, Q9H7E7	Gene names	HHIP, HIP
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

KR104_HUMAN
NC score	0.112414 (rank : 242)	θ value	θ > 10 (rank : 248)
Query Neighborhood Hits	162	Target Neighborhood Hits	313	Shared Neighborhood Hits	77
SwissProt Accessions	P60372	Gene names	KRTAP10-4, KAP10.4, KAP18-4, KRTAP10.4, KRTAP18-4, KRTAP18.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-4 (Keratin-associated protein 10.4) (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4).

GP126_HUMAN
NC score	0.111383 (rank : 243)	θ value	θ > 10 (rank : 225)
Query Neighborhood Hits	162	Target Neighborhood Hits	187	Shared Neighborhood Hits	23
SwissProt Accessions	Q86SQ4, Q6MZU7, Q8NC14, Q96JW0	Gene names	GPR126
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 126 precursor.

KREM2_HUMAN
NC score	0.111294 (rank : 244)	θ value	θ > 10 (rank : 282)
Query Neighborhood Hits	162	Target Neighborhood Hits	93	Shared Neighborhood Hits	19
SwissProt Accessions	Q8NCW0, Q8N2J4, Q8NCW1, Q96GL8, Q9BTP9	Gene names	KREMEN2, KRM2
Domain Architecture
Description	Kremen protein 2 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 2) (Dickkopf receptor 2).

CELR3_MOUSE
NC score	0.111072 (rank : 245)	θ value	0.0961366 (rank : 57)
Query Neighborhood Hits	162	Target Neighborhood Hits	687	Shared Neighborhood Hits	128
SwissProt Accessions	Q91ZI0, Q9ESD0	Gene names	Celsr3
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 3 precursor.

HHIP_MOUSE
NC score	0.110727 (rank : 246)	θ value	θ > 10 (rank : 229)
Query Neighborhood Hits	162	Target Neighborhood Hits	219	Shared Neighborhood Hits	76
SwissProt Accessions	Q7TN16, Q8C0B0, Q9WU59	Gene names	Hhip, Hip
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

PGCB_MOUSE
NC score	0.110105 (rank : 247)	θ value	1.06291 (rank : 112)
Query Neighborhood Hits	162	Target Neighborhood Hits	459	Shared Neighborhood Hits	110
SwissProt Accessions	Q61361	Gene names	Bcan
Domain Architecture
Description	Brevican core protein precursor.

LYAM3_MOUSE
NC score	0.107338 (rank : 248)	θ value	3.0926 (rank : 132)
Query Neighborhood Hits	162	Target Neighborhood Hits	390	Shared Neighborhood Hits	120
SwissProt Accessions	Q01102	Gene names	Selp, Grmp
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

PROC_MOUSE
NC score	0.106848 (rank : 249)	θ value	θ > 10 (rank : 382)
Query Neighborhood Hits	162	Target Neighborhood Hits	426	Shared Neighborhood Hits	124
SwissProt Accessions	P33587, O35498, Q91WN8, Q99PC6	Gene names	Proc
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

DCBD1_MOUSE
NC score	0.106772 (rank : 250)	θ value	θ > 10 (rank : 202)
Query Neighborhood Hits	162	Target Neighborhood Hits	89	Shared Neighborhood Hits	13
SwissProt Accessions	Q9D4J3, Q8R327, Q9D696	Gene names	Dcbld1
Domain Architecture	No domain graphic available
Description	Discoidin, CUB and LCCL domain-containing protein 1 precursor.

MMRN1_HUMAN
NC score	0.106547 (rank : 251)	θ value	0.365318 (rank : 90)
Query Neighborhood Hits	162	Target Neighborhood Hits	636	Shared Neighborhood Hits	101
SwissProt Accessions	Q13201, Q6P3T8	Gene names	MMRN1, ECM, EMILIN4, MMRN
Domain Architecture
Description	Multimerin-1 precursor (Endothelial cell multimerin 1) (EMILIN-4) (Elastin microfibril interface located protein 4) (Elastin microfibril interfacer 4).

CELR1_MOUSE
NC score	0.105894 (rank : 252)	θ value	1.38821 (rank : 114)
Query Neighborhood Hits	162	Target Neighborhood Hits	617	Shared Neighborhood Hits	127
SwissProt Accessions	O35161	Gene names	Celsr1
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor.

KREM2_MOUSE
NC score	0.105892 (rank : 253)	θ value	θ > 10 (rank : 283)
Query Neighborhood Hits	162	Target Neighborhood Hits	90	Shared Neighborhood Hits	18
SwissProt Accessions	Q8K1S7	Gene names	Kremen2
Domain Architecture
Description	Kremen protein 2 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 2) (Dickkopf receptor 2).

CELR1_HUMAN
NC score	0.105836 (rank : 254)	θ value	0.365318 (rank : 87)
Query Neighborhood Hits	162	Target Neighborhood Hits	613	Shared Neighborhood Hits	130
SwissProt Accessions	Q9NYQ6, O95722, Q5TH47, Q9BWQ5, Q9Y506, Q9Y526	Gene names	CELSR1, CDHF9, FMI2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 1 precursor (Flamingo homolog 2) (hFmi2).

PGBM_HUMAN
NC score	0.105696 (rank : 255)	θ value	θ > 10 (rank : 376)
Query Neighborhood Hits	162	Target Neighborhood Hits	1113	Shared Neighborhood Hits	129
SwissProt Accessions	P98160, Q16287, Q9H3V5	Gene names	HSPG2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

FA7_HUMAN
NC score	0.104902 (rank : 256)	θ value	θ > 10 (rank : 215)
Query Neighborhood Hits	162	Target Neighborhood Hits	404	Shared Neighborhood Hits	129
SwissProt Accessions	P08709, Q14339, Q5JVF2	Gene names	F7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) (SPCA) (Proconvertin) (Eptacog alfa) [Contains: Factor VII light chain; Factor VII heavy chain].

CFC1_HUMAN
NC score	0.104888 (rank : 257)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	162	Target Neighborhood Hits	148	Shared Neighborhood Hits	81
SwissProt Accessions	Q9GZR3, Q53T05	Gene names	CFC1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

NAGPA_HUMAN
NC score	0.104656 (rank : 258)	θ value	θ > 10 (rank : 348)
Query Neighborhood Hits	162	Target Neighborhood Hits	282	Shared Neighborhood Hits	79
SwissProt Accessions	Q9UK23, Q96EJ8	Gene names	NAGPA
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

ELTD1_HUMAN
NC score	0.104210 (rank : 259)	θ value	θ > 10 (rank : 211)
Query Neighborhood Hits	162	Target Neighborhood Hits	269	Shared Neighborhood Hits	105
SwissProt Accessions	Q9HBW9	Gene names	ELTD1, ETL
Domain Architecture
Description	EGF, latrophilin and seven transmembrane domain-containing protein 1 precursor (EGF-TM7-latrophilin-related protein) (ETL protein).

NRG2_MOUSE
NC score	0.104079 (rank : 260)	θ value	1.06291 (rank : 111)
Query Neighborhood Hits	162	Target Neighborhood Hits	392	Shared Neighborhood Hits	83
SwissProt Accessions	P56974	Gene names	Nrg2
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Divergent of neuregulin 1) (DON-1)].

CELR2_MOUSE
NC score	0.104045 (rank : 261)	θ value	0.47712 (rank : 91)
Query Neighborhood Hits	162	Target Neighborhood Hits	584	Shared Neighborhood Hits	126
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

HGFA_HUMAN
NC score	0.103578 (rank : 262)	θ value	0.813845 (rank : 101)
Query Neighborhood Hits	162	Target Neighborhood Hits	436	Shared Neighborhood Hits	116
SwissProt Accessions	Q04756, Q14726	Gene names	HGFAC
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

PGCB_HUMAN
NC score	0.103530 (rank : 263)	θ value	1.81305 (rank : 123)
Query Neighborhood Hits	162	Target Neighborhood Hits	478	Shared Neighborhood Hits	107
SwissProt Accessions	Q96GW7, Q8TBB9, Q9HBK1, Q9HBK4	Gene names	BCAN, BEHAB, CSPG7
Domain Architecture	No domain graphic available
Description	Brevican core protein precursor (Brain-enriched hyaluronan-binding protein) (Protein BEHAB).

PGBM_MOUSE
NC score	0.103429 (rank : 264)	θ value	θ > 10 (rank : 377)
Query Neighborhood Hits	162	Target Neighborhood Hits	1073	Shared Neighborhood Hits	129
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

NAGPA_MOUSE
NC score	0.102482 (rank : 265)	θ value	θ > 10 (rank : 349)
Query Neighborhood Hits	162	Target Neighborhood Hits	308	Shared Neighborhood Hits	91
SwissProt Accessions	Q8BJ48, Q3UUT5, Q8CHQ8, Q9QZE6	Gene names	Nagpa
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase precursor (EC 3.1.4.45) (Phosphodiester alpha-GlcNAcase) (Mannose 6- phosphate-uncovering enzyme).

CFC1_MOUSE
NC score	0.101756 (rank : 266)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	162	Target Neighborhood Hits	125	Shared Neighborhood Hits	78
SwissProt Accessions	P97766, Q496U5, Q9JIB7	Gene names	Cfc1
Domain Architecture	No domain graphic available
Description	Cryptic protein precursor.

KREM1_HUMAN
NC score	0.101345 (rank : 267)	θ value	θ > 10 (rank : 280)
Query Neighborhood Hits	162	Target Neighborhood Hits	90	Shared Neighborhood Hits	18
SwissProt Accessions	Q96MU8, Q5TIB9, Q6P3X6, Q9BY70, Q9UGS5, Q9UGU1	Gene names	KREMEN1, KREMEN, KRM1
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

HGFA_MOUSE
NC score	0.100873 (rank : 268)	θ value	6.88961 (rank : 147)
Query Neighborhood Hits	162	Target Neighborhood Hits	419	Shared Neighborhood Hits	117
SwissProt Accessions	Q9R098, Q9JKV4	Gene names	Hgfac
Domain Architecture
Description	Hepatocyte growth factor activator precursor (EC 3.4.21.-) (HGF activator) (HGFA) [Contains: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain].

ST14_MOUSE
NC score	0.100620 (rank : 269)	θ value	θ > 10 (rank : 394)
Query Neighborhood Hits	162	Target Neighborhood Hits	419	Shared Neighborhood Hits	89
SwissProt Accessions	P56677	Gene names	St14, Prss14
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Epithin).

ST14_HUMAN
NC score	0.099430 (rank : 270)	θ value	θ > 10 (rank : 393)
Query Neighborhood Hits	162	Target Neighborhood Hits	409	Shared Neighborhood Hits	79
SwissProt Accessions	Q9Y5Y6, Q9BS01, Q9H3S0, Q9HB36, Q9HCA3	Gene names	ST14, PRSS14, SNC19, TADG15
Domain Architecture
Description	Suppressor of tumorigenicity protein 14 (EC 3.4.21.-) (Serine protease 14) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein).

PROC_HUMAN
NC score	0.098898 (rank : 271)	θ value	θ > 10 (rank : 381)
Query Neighborhood Hits	162	Target Neighborhood Hits	406	Shared Neighborhood Hits	119
SwissProt Accessions	P04070, Q15189, Q15190, Q16001	Gene names	PROC
Domain Architecture
Description	Vitamin K-dependent protein C precursor (EC 3.4.21.69) (Autoprothrombin IIA) (Anticoagulant protein C) (Blood coagulation factor XIV) [Contains: Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide].

LAMA5_MOUSE
NC score	0.098646 (rank : 272)	θ value	θ > 10 (rank : 293)
Query Neighborhood Hits	162	Target Neighborhood Hits	828	Shared Neighborhood Hits	120
SwissProt Accessions	Q61001, Q9JHQ6	Gene names	Lama5
Domain Architecture
Description	Laminin alpha-5 chain precursor.

NRX3A_HUMAN
NC score	0.098600 (rank : 273)	θ value	1.38821 (rank : 117)
Query Neighborhood Hits	162	Target Neighborhood Hits	164	Shared Neighborhood Hits	93
SwissProt Accessions	Q9Y4C0, O95378, Q9NS47, Q9P1V3, Q9P1V6, Q9UIE2, Q9UIE3, Q9ULA5, Q9Y486	Gene names	NRXN3, KIAA0743
Domain Architecture
Description	Neurexin-3-alpha precursor (Neurexin III-alpha).

GRN_MOUSE
NC score	0.098556 (rank : 274)	θ value	θ > 10 (rank : 227)
Query Neighborhood Hits	162	Target Neighborhood Hits	248	Shared Neighborhood Hits	71
SwissProt Accessions	P28798	Gene names	Grn
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) (PC cell-derived growth factor) (PCDGF) [Contains: Acrogranin; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7].

FA7_MOUSE
NC score	0.098177 (rank : 275)	θ value	8.99809 (rank : 153)
Query Neighborhood Hits	162	Target Neighborhood Hits	374	Shared Neighborhood Hits	124
SwissProt Accessions	P70375, Q61109	Gene names	F7, Cf7
Domain Architecture
Description	Coagulation factor VII precursor (EC 3.4.21.21) (Serum prothrombin conversion accelerator) [Contains: Factor VII light chain; Factor VII heavy chain].

KRA53_HUMAN
NC score	0.097602 (rank : 276)	θ value	θ > 10 (rank : 269)
Query Neighborhood Hits	162	Target Neighborhood Hits	331	Shared Neighborhood Hits	74
SwissProt Accessions	Q6L8H2, Q6PL44, Q701N3	Gene names	KRTAP5-3, KAP5-9, KAP5.3, KRTAP5-9, KRTAP5.3, KRTAP5.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-3 (Keratin-associated protein 5.3) (Ultrahigh sulfur keratin-associated protein 5.3) (Keratin-associated protein 5-9) (Keratin-associated protein 5.9) (UHS KerB-like).

NTNG2_HUMAN
NC score	0.097237 (rank : 277)	θ value	8.99809 (rank : 157)
Query Neighborhood Hits	162	Target Neighborhood Hits	276	Shared Neighborhood Hits	101
SwissProt Accessions	Q96CW9, Q6UXY0, Q96JH0	Gene names	NTNG2, KIAA1857, LMNT2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

TDGF1_MOUSE
NC score	0.097139 (rank : 278)	θ value	θ > 10 (rank : 400)
Query Neighborhood Hits	162	Target Neighborhood Hits	146	Shared Neighborhood Hits	81
SwissProt Accessions	P51865	Gene names	Tdgf1, Cripto
Domain Architecture
Description	Teratocarcinoma-derived growth factor precursor (Epidermal growth factor-like Cripto protein) (Cripto growth factor).

NRX1A_HUMAN
NC score	0.096762 (rank : 279)	θ value	4.03905 (rank : 138)
Query Neighborhood Hits	162	Target Neighborhood Hits	170	Shared Neighborhood Hits	86
SwissProt Accessions	Q9ULB1, O60323, Q53TJ9, Q53TQ1, Q9C079, Q9C080, Q9C081, Q9H3M2, Q9UDM6	Gene names	NRXN1, KIAA0578
Domain Architecture
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

KRA51_HUMAN
NC score	0.096608 (rank : 280)	θ value	θ > 10 (rank : 267)
Query Neighborhood Hits	162	Target Neighborhood Hits	288	Shared Neighborhood Hits	64
SwissProt Accessions	Q6L8H4	Gene names	KRTAP5-1, KAP5.1, KRTAP5.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-1 (Keratin-associated protein 5.1) (Ultrahigh sulfur keratin-associated protein 5.1).

NRX1A_MOUSE
NC score	0.096002 (rank : 281)	θ value	5.27518 (rank : 143)
Query Neighborhood Hits	162	Target Neighborhood Hits	164	Shared Neighborhood Hits	86
SwissProt Accessions	Q9CS84, O88722, Q80Y87, Q8CHE6	Gene names	Nrxn1, Kiaa0578
Domain Architecture	No domain graphic available
Description	Neurexin-1-alpha precursor (Neurexin I-alpha).

UROL1_MOUSE
NC score	0.095923 (rank : 282)	θ value	θ > 10 (rank : 431)
Query Neighborhood Hits	162	Target Neighborhood Hits	235	Shared Neighborhood Hits	79
SwissProt Accessions	Q5DID3, Q5DID1, Q5DID2	Gene names	Umodl1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

NTNG2_MOUSE
NC score	0.095822 (rank : 283)	θ value	θ > 10 (rank : 366)
Query Neighborhood Hits	162	Target Neighborhood Hits	276	Shared Neighborhood Hits	99
SwissProt Accessions	Q8R4F1, Q8R4F2, Q8VIP6, Q8VIP7, Q8VIP8	Gene names	Ntng2, Lmnt2
Domain Architecture
Description	Netrin G2 precursor (Laminet-2).

GRN_HUMAN
NC score	0.095746 (rank : 284)	θ value	θ > 10 (rank : 226)
Query Neighborhood Hits	162	Target Neighborhood Hits	268	Shared Neighborhood Hits	73
SwissProt Accessions	P28799, P23781, P23782, P23783, P23784, Q9BWE7, Q9UCH0	Gene names	GRN
Domain Architecture
Description	Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin; Paragranulin; Granulin-1 (Granulin G); Granulin-2 (Granulin F); Granulin-3 (Granulin B); Granulin-4 (Granulin A); Granulin-5 (Granulin C); Granulin-6 (Granulin D); Granulin-7 (Granulin E)].

KR101_HUMAN
NC score	0.095690 (rank : 285)	θ value	θ > 10 (rank : 245)
Query Neighborhood Hits	162	Target Neighborhood Hits	261	Shared Neighborhood Hits	62
SwissProt Accessions	P60331	Gene names	KRTAP10-1, KAP10.1, KAP18-1, KRTAP10.1, KRTAP18-1, KRTAP18.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-1 (Keratin-associated protein 10.1) (High sulfur keratin-associated protein 10.1) (Keratin-associated protein 18-1) (Keratin-associated protein 18.1).

FA12_HUMAN
NC score	0.095254 (rank : 286)	θ value	0.813845 (rank : 98)
Query Neighborhood Hits	162	Target Neighborhood Hits	425	Shared Neighborhood Hits	107
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

FAT2_HUMAN
NC score	0.094479 (rank : 287)	θ value	5.27518 (rank : 140)
Query Neighborhood Hits	162	Target Neighborhood Hits	507	Shared Neighborhood Hits	110
SwissProt Accessions	Q9NYQ8, O75091, Q9NSR7	Gene names	FAT2, CDHF8, KIAA0811, MEGF1
Domain Architecture
Description	Protocadherin Fat 2 precursor (hFat2) (Multiple epidermal growth factor-like domains 1).

LAMA5_HUMAN
NC score	0.094195 (rank : 288)	θ value	θ > 10 (rank : 292)
Query Neighborhood Hits	162	Target Neighborhood Hits	976	Shared Neighborhood Hits	114
SwissProt Accessions	O15230, Q8WZA7, Q9H1P1	Gene names	LAMA5, KIAA0533, KIAA1907
Domain Architecture
Description	Laminin alpha-5 chain precursor.

PERT_HUMAN
NC score	0.093501 (rank : 289)	θ value	θ > 10 (rank : 374)
Query Neighborhood Hits	162	Target Neighborhood Hits	221	Shared Neighborhood Hits	91
SwissProt Accessions	P07202, P09934, P09935, Q8IUL0, Q8NF94, Q8NF95, Q8NF96, Q8NF97, Q8TCI9	Gene names	TPO
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

LAMB2_HUMAN
NC score	0.092850 (rank : 290)	θ value	θ > 10 (rank : 296)
Query Neighborhood Hits	162	Target Neighborhood Hits	692	Shared Neighborhood Hits	109
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

MEGF9_HUMAN
NC score	0.092701 (rank : 291)	θ value	θ > 10 (rank : 343)
Query Neighborhood Hits	162	Target Neighborhood Hits	557	Shared Neighborhood Hits	96
SwissProt Accessions	Q9H1U4, O75098	Gene names	MEGF9, EGFL5, KIAA0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

LYAM2_MOUSE
NC score	0.092454 (rank : 292)	θ value	θ > 10 (rank : 328)
Query Neighborhood Hits	162	Target Neighborhood Hits	420	Shared Neighborhood Hits	114
SwissProt Accessions	Q00690	Gene names	Sele, Elam-1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

CLC14_MOUSE
NC score	0.092251 (rank : 293)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	162	Target Neighborhood Hits	120	Shared Neighborhood Hits	67
SwissProt Accessions	Q8VCP9, Q3TP72, Q9CXA8, Q9D624, Q9DC55	Gene names	Clec14a
Domain Architecture
Description	C-type lectin domain family 14 member A precursor.

KRA58_HUMAN
NC score	0.091903 (rank : 294)	θ value	θ > 10 (rank : 273)
Query Neighborhood Hits	162	Target Neighborhood Hits	324	Shared Neighborhood Hits	64
SwissProt Accessions	O75690, Q6L8G7, Q6UTX6	Gene names	KRTAP5-8, KAP5.8, KRTAP5.8, UHSKB
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-8 (Keratin-associated protein 5.8) (Ultrahigh sulfur keratin-associated protein 5.8) (Keratin, ultra high-sulfur matrix protein B) (UHS keratin B) (UHS KerB).

KREM1_MOUSE
NC score	0.091631 (rank : 295)	θ value	θ > 10 (rank : 281)
Query Neighborhood Hits	162	Target Neighborhood Hits	92	Shared Neighborhood Hits	19
SwissProt Accessions	Q99N43	Gene names	Kremen1, Kremen
Domain Architecture
Description	Kremen protein 1 precursor (Kringle-containing protein marking the eye and the nose) (Kringle domain-containing transmembrane protein 1) (Dickkopf receptor).

LYAM2_HUMAN
NC score	0.091474 (rank : 296)	θ value	θ > 10 (rank : 327)
Query Neighborhood Hits	162	Target Neighborhood Hits	394	Shared Neighborhood Hits	117
SwissProt Accessions	P16581, P16111	Gene names	SELE, ELAM1
Domain Architecture
Description	E-selectin precursor (Endothelial leukocyte adhesion molecule 1) (ELAM-1) (Leukocyte-endothelial cell adhesion molecule 2) (LECAM2) (CD62E antigen).

LAMB1_MOUSE
NC score	0.090781 (rank : 297)	θ value	θ > 10 (rank : 295)
Query Neighborhood Hits	162	Target Neighborhood Hits	919	Shared Neighborhood Hits	112
SwissProt Accessions	P02469	Gene names	Lamb1-1, Lamb-1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

PGH1_MOUSE
NC score	0.090237 (rank : 298)	θ value	8.99809 (rank : 158)
Query Neighborhood Hits	162	Target Neighborhood Hits	100	Shared Neighborhood Hits	67
SwissProt Accessions	P22437	Gene names	Ptgs1, Cox-1, Cox1
Domain Architecture
Description	Prostaglandin G/H synthase 1 precursor (EC 1.14.99.1) (Cyclooxygenase- 1) (COX-1) (Prostaglandin-endoperoxide synthase 1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1).

LAMB2_MOUSE
NC score	0.090133 (rank : 299)	θ value	θ > 10 (rank : 297)
Query Neighborhood Hits	162	Target Neighborhood Hits	722	Shared Neighborhood Hits	104
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

CLC14_HUMAN
NC score	0.089714 (rank : 300)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	162	Target Neighborhood Hits	143	Shared Neighborhood Hits	70
SwissProt Accessions	Q86T13, Q6PWT6, Q8N5V5	Gene names	CLEC14A, C14orf27, EGFR5
Domain Architecture
Description	C-type lectin domain family 14 member A precursor (Epidermal growth factor receptor 5) (EGFR-5).

LAMC2_MOUSE
NC score	0.089681 (rank : 301)	θ value	θ > 10 (rank : 303)
Query Neighborhood Hits	162	Target Neighborhood Hits	614	Shared Neighborhood Hits	102
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

LAMA1_MOUSE
NC score	0.089247 (rank : 302)	θ value	θ > 10 (rank : 285)
Query Neighborhood Hits	162	Target Neighborhood Hits	838	Shared Neighborhood Hits	114
SwissProt Accessions	P19137	Gene names	Lama1, Lama, Lama-1
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LAMC3_MOUSE
NC score	0.088849 (rank : 303)	θ value	θ > 10 (rank : 305)
Query Neighborhood Hits	162	Target Neighborhood Hits	624	Shared Neighborhood Hits	105
SwissProt Accessions	Q9R0B6, Q9WTW6	Gene names	Lamc3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

LAMA1_HUMAN
NC score	0.088536 (rank : 304)	θ value	θ > 10 (rank : 284)
Query Neighborhood Hits	162	Target Neighborhood Hits	804	Shared Neighborhood Hits	106
SwissProt Accessions	P25391	Gene names	LAMA1, LAMA
Domain Architecture
Description	Laminin alpha-1 chain precursor (Laminin A chain).

LYAM3_HUMAN
NC score	0.087625 (rank : 305)	θ value	θ > 10 (rank : 329)
Query Neighborhood Hits	162	Target Neighborhood Hits	378	Shared Neighborhood Hits	114
SwissProt Accessions	P16109, Q8IVD1	Gene names	SELP, GMRP
Domain Architecture
Description	P-selectin precursor (Granule membrane protein 140) (GMP-140) (PADGEM) (Leukocyte-endothelial cell adhesion molecule 3) (LECAM3) (CD62P antigen).

LAMC3_HUMAN
NC score	0.087271 (rank : 306)	θ value	θ > 10 (rank : 304)
Query Neighborhood Hits	162	Target Neighborhood Hits	588	Shared Neighborhood Hits	106
SwissProt Accessions	Q9Y6N6	Gene names	LAMC3
Domain Architecture
Description	Laminin gamma-3 chain precursor (Laminin 12 gamma 3 subunit).

CNTP3_HUMAN
NC score	0.087201 (rank : 307)	θ value	6.88961 (rank : 146)
Query Neighborhood Hits	162	Target Neighborhood Hits	195	Shared Neighborhood Hits	97
SwissProt Accessions	Q9BZ76, Q9C0E9	Gene names	CNTNAP3, CASPR3, KIAA1714
Domain Architecture
Description	Contactin-associated protein-like 3 precursor (Cell recognition molecule Caspr3).

KR102_HUMAN
NC score	0.087177 (rank : 308)	θ value	θ > 10 (rank : 246)
Query Neighborhood Hits	162	Target Neighborhood Hits	264	Shared Neighborhood Hits	61
SwissProt Accessions	P60368, Q70LJ5	Gene names	KRTAP10-2, KAP10.2, KAP18-2, KRTAP10.2, KRTAP18-2, KRTAP18.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-2 (Keratin-associated protein 10.2) (High sulfur keratin-associated protein 10.2) (Keratin-associated protein 18-2) (Keratin-associated protein 18.2).

CNTP2_HUMAN
NC score	0.086829 (rank : 309)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	162	Target Neighborhood Hits	199	Shared Neighborhood Hits	103
SwissProt Accessions	Q9UHC6, Q52LV1, Q5H9Q7, Q9UQ12	Gene names	CNTNAP2, CASPR2, KIAA0868
Domain Architecture
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

LAMC2_HUMAN
NC score	0.086562 (rank : 310)	θ value	θ > 10 (rank : 302)
Query Neighborhood Hits	162	Target Neighborhood Hits	715	Shared Neighborhood Hits	97
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

CNTP2_MOUSE
NC score	0.086534 (rank : 311)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	162	Target Neighborhood Hits	194	Shared Neighborhood Hits	100
SwissProt Accessions	Q9CPW0, Q6P2K4, Q6ZQ31	Gene names	Cntnap2, Kiaa0868
Domain Architecture	No domain graphic available
Description	Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2).

PERT_MOUSE
NC score	0.086528 (rank : 312)	θ value	θ > 10 (rank : 375)
Query Neighborhood Hits	162	Target Neighborhood Hits	221	Shared Neighborhood Hits	82
SwissProt Accessions	P35419, Q8C8B1	Gene names	Tpo
Domain Architecture
Description	Thyroid peroxidase precursor (EC 1.11.1.8) (TPO).

MEGF9_MOUSE
NC score	0.085959 (rank : 313)	θ value	θ > 10 (rank : 344)
Query Neighborhood Hits	162	Target Neighborhood Hits	896	Shared Neighborhood Hits	91
SwissProt Accessions	Q8BH27, Q8BWI4	Gene names	Megf9, Egfl5, Kiaa0818
Domain Architecture
Description	Multiple epidermal growth factor-like domains 9 precursor (EGF-like domain-containing protein 5) (Multiple EGF-like domain protein 5).

TDGF1_HUMAN
NC score	0.085570 (rank : 314)	θ value	θ > 10 (rank : 399)
Query Neighborhood Hits	162	Target Neighborhood Hits	132	Shared Neighborhood Hits	78
SwissProt Accessions	P13385	Gene names	TDGF1, CRIPTO
Domain Architecture
Description	Teratocarcinoma-derived growth factor 1 precursor (Epidermal growth factor-like cripto protein CR1) (Cripto-1 growth factor) (CRGF).

TSP1_MOUSE
NC score	0.084752 (rank : 315)	θ value	θ > 10 (rank : 423)
Query Neighborhood Hits	162	Target Neighborhood Hits	396	Shared Neighborhood Hits	99
SwissProt Accessions	P35441	Gene names	Thbs1, Tsp1
Domain Architecture
Description	Thrombospondin-1 precursor.

CNTP4_MOUSE
NC score	0.084423 (rank : 316)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	162	Target Neighborhood Hits	193	Shared Neighborhood Hits	94
SwissProt Accessions	Q99P47	Gene names	Cntnap4, Caspr4
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

LAMB1_HUMAN
NC score	0.084326 (rank : 317)	θ value	θ > 10 (rank : 294)
Query Neighborhood Hits	162	Target Neighborhood Hits	1018	Shared Neighborhood Hits	108
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

KR109_HUMAN
NC score	0.084304 (rank : 318)	θ value	θ > 10 (rank : 253)
Query Neighborhood Hits	162	Target Neighborhood Hits	226	Shared Neighborhood Hits	64
SwissProt Accessions	P60411, Q70LJ1	Gene names	KRTAP10-9, KAP10.9, KAP18-9, KRTAP10.9, KRTAP18-9, KRTAP18.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-9 (Keratin-associated protein 10.9) (High sulfur keratin-associated protein 10.9) (Keratin-associated protein 18-9) (Keratin-associated protein 18.9).

NRG2_HUMAN
NC score	0.083093 (rank : 319)	θ value	θ > 10 (rank : 359)
Query Neighborhood Hits	162	Target Neighborhood Hits	419	Shared Neighborhood Hits	67
SwissProt Accessions	O14511	Gene names	NRG2, NTAK
Domain Architecture
Description	Pro-neuregulin-2, membrane-bound isoform precursor (Pro-NRG2) [Contains: Neuregulin-2 (NRG-2) (Neural- and thymus-derived activator for ERBB kinases) (NTAK) (Divergent of neuregulin-1) (DON-1)].

EMR3_HUMAN
NC score	0.082911 (rank : 320)	θ value	θ > 10 (rank : 213)
Query Neighborhood Hits	162	Target Neighborhood Hits	245	Shared Neighborhood Hits	90
SwissProt Accessions	Q9BY15	Gene names	EMR3
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 3 precursor (EGF-like module-containing mucin-like receptor EMR3).

ITB6_MOUSE
NC score	0.082874 (rank : 321)	θ value	θ > 10 (rank : 241)
Query Neighborhood Hits	162	Target Neighborhood Hits	341	Shared Neighborhood Hits	96
SwissProt Accessions	Q9Z0T9	Gene names	Itgb6
Domain Architecture
Description	Integrin beta-6 precursor.

TSP1_HUMAN
NC score	0.082599 (rank : 322)	θ value	θ > 10 (rank : 422)
Query Neighborhood Hits	162	Target Neighborhood Hits	389	Shared Neighborhood Hits	97
SwissProt Accessions	P07996, Q15667	Gene names	THBS1, TSP, TSP1
Domain Architecture
Description	Thrombospondin-1 precursor.

LAMA2_HUMAN
NC score	0.082208 (rank : 323)	θ value	θ > 10 (rank : 286)
Query Neighborhood Hits	162	Target Neighborhood Hits	1092	Shared Neighborhood Hits	112
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

CNTP4_HUMAN
NC score	0.082178 (rank : 324)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	162	Target Neighborhood Hits	187	Shared Neighborhood Hits	91
SwissProt Accessions	Q9C0A0	Gene names	CNTNAP4, CASPR4, KIAA1763
Domain Architecture
Description	Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4).

KRA59_HUMAN
NC score	0.081898 (rank : 325)	θ value	θ > 10 (rank : 274)
Query Neighborhood Hits	162	Target Neighborhood Hits	310	Shared Neighborhood Hits	54
SwissProt Accessions	P26371, Q14564	Gene names	KRTAP5-9, KAP5.9, KRN1, KRTAP5.9, UHSK1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-9 (Keratin-associated protein 5.9) (Ultrahigh sulfur keratin-associated protein 5.9) (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (UHS keratin A) (UHS KerA).

NTNG1_HUMAN
NC score	0.081806 (rank : 326)	θ value	θ > 10 (rank : 364)
Query Neighborhood Hits	162	Target Neighborhood Hits	247	Shared Neighborhood Hits	90
SwissProt Accessions	Q9Y2I2, Q5VU86, Q5VU87, Q5VU89, Q5VU90, Q5VU91, Q7Z2Y3, Q8N633	Gene names	NTNG1, KIAA0976, LMNT1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

TDGF2_HUMAN
NC score	0.081763 (rank : 327)	θ value	θ > 10 (rank : 401)
Query Neighborhood Hits	162	Target Neighborhood Hits	131	Shared Neighborhood Hits	77
SwissProt Accessions	P51864	Gene names	TDGF3, TDGF2
Domain Architecture
Description	Teratocarcinoma-derived growth factor 2 (Epidermal growth factor-like cripto protein CR3) (Cripto-3 growth factor).

NTNG1_MOUSE
NC score	0.081241 (rank : 328)	θ value	θ > 10 (rank : 365)
Query Neighborhood Hits	162	Target Neighborhood Hits	246	Shared Neighborhood Hits	88
SwissProt Accessions	Q8R4G0, Q68FE5, Q69ZU3, Q8R4F3, Q8R4F4, Q8R4F5, Q8R4F6, Q8R4F7, Q8R4F8, Q8R4F9, Q9ESR3, Q9ESR4, Q9ESR5, Q9ESR6, Q9ESR7, Q9ESR8	Gene names	Ntng1, Kiaa0976, Lmnt1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

TEFF2_HUMAN
NC score	0.080803 (rank : 329)	θ value	θ > 10 (rank : 403)
Query Neighborhood Hits	162	Target Neighborhood Hits	211	Shared Neighborhood Hits	68
SwissProt Accessions	Q9UIK5, Q4ZFW4, Q53H90, Q53RE1, Q8N2R5, Q9NR15, Q9NSS5, Q9P2Y9, Q9UK65	Gene names	TMEFF2, HPP1, TENB2, TPEF
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Transmembrane protein containing epidermal growth factor and follistatin domains) (Tomoregulin) (TR) (Hyperplastic polyposis protein 1).

KR105_HUMAN
NC score	0.080647 (rank : 330)	θ value	θ > 10 (rank : 249)
Query Neighborhood Hits	162	Target Neighborhood Hits	271	Shared Neighborhood Hits	66
SwissProt Accessions	P60370, Q70LJ3	Gene names	KRTAP10-5, KAP10.5, KAP18-5, KRTAP10.5, KRTAP18-5, KRTAP18.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-5 (Keratin-associated protein 10.5) (High sulfur keratin-associated protein 10.5) (Keratin-associated protein 18-5) (Keratin-associated protein 18.5).

TEFF2_MOUSE
NC score	0.080582 (rank : 331)	θ value	θ > 10 (rank : 404)
Query Neighborhood Hits	162	Target Neighborhood Hits	214	Shared Neighborhood Hits	71
SwissProt Accessions	Q9QYM9, Q3UY20, Q8CDH1, Q9JJE3	Gene names	Tmeff2
Domain Architecture	No domain graphic available
Description	Transmembrane protein with EGF-like and two follistatin-like domains 2 precursor (Tomoregulin) (TR).

ITB7_HUMAN
NC score	0.079917 (rank : 332)	θ value	θ > 10 (rank : 242)
Query Neighborhood Hits	162	Target Neighborhood Hits	290	Shared Neighborhood Hits	95
SwissProt Accessions	P26010	Gene names	ITGB7
Domain Architecture
Description	Integrin beta-7 precursor.

ITB6_HUMAN
NC score	0.079841 (rank : 333)	θ value	θ > 10 (rank : 240)
Query Neighborhood Hits	162	Target Neighborhood Hits	318	Shared Neighborhood Hits	87
SwissProt Accessions	P18564, Q16500	Gene names	ITGB6
Domain Architecture
Description	Integrin beta-6 precursor.

LAMC1_MOUSE
NC score	0.079698 (rank : 334)	θ value	θ > 10 (rank : 301)
Query Neighborhood Hits	162	Target Neighborhood Hits	856	Shared Neighborhood Hits	103
SwissProt Accessions	P02468	Gene names	Lamc1, Lamb-2, Lamc-1
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

TENR_MOUSE
NC score	0.079101 (rank : 335)	θ value	θ > 10 (rank : 410)
Query Neighborhood Hits	162	Target Neighborhood Hits	531	Shared Neighborhood Hits	101
SwissProt Accessions	Q8BYI9, O88717	Gene names	Tnr
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin) (Neural recognition molecule J1-160/180).

TENR_HUMAN
NC score	0.078602 (rank : 336)	θ value	θ > 10 (rank : 409)
Query Neighborhood Hits	162	Target Neighborhood Hits	526	Shared Neighborhood Hits	100
SwissProt Accessions	Q92752, Q15568, Q5R3G0	Gene names	TNR
Domain Architecture	No domain graphic available
Description	Tenascin-R precursor (TN-R) (Restrictin) (Janusin).

ITB5_MOUSE
NC score	0.078536 (rank : 337)	θ value	θ > 10 (rank : 239)
Query Neighborhood Hits	162	Target Neighborhood Hits	329	Shared Neighborhood Hits	98
SwissProt Accessions	O70309, O70308, O88347	Gene names	Itgb5
Domain Architecture
Description	Integrin beta-5 precursor.

KR108_HUMAN
NC score	0.078378 (rank : 338)	θ value	θ > 10 (rank : 252)
Query Neighborhood Hits	162	Target Neighborhood Hits	226	Shared Neighborhood Hits	57
SwissProt Accessions	P60410	Gene names	KRTAP10-8, KAP10.8, KAP18-8, KRTAP10.8, KRTAP18-8, KRTAP18.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-8 (Keratin-associated protein 10.8) (High sulfur keratin-associated protein 10.8) (Keratin-associated protein 18-8) (Keratin-associated protein 18.8).

LAMA2_MOUSE
NC score	0.078032 (rank : 339)	θ value	θ > 10 (rank : 287)
Query Neighborhood Hits	162	Target Neighborhood Hits	1198	Shared Neighborhood Hits	112
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMC1_HUMAN
NC score	0.077994 (rank : 340)	θ value	θ > 10 (rank : 300)
Query Neighborhood Hits	162	Target Neighborhood Hits	922	Shared Neighborhood Hits	105
SwissProt Accessions	P11047	Gene names	LAMC1, LAMB2
Domain Architecture
Description	Laminin gamma-1 chain precursor (Laminin B2 chain).

MATN1_MOUSE
NC score	0.077899 (rank : 341)	θ value	θ > 10 (rank : 335)
Query Neighborhood Hits	162	Target Neighborhood Hits	186	Shared Neighborhood Hits	68
SwissProt Accessions	P51942	Gene names	Matn1, Cmp, Crtm
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

UROL1_HUMAN
NC score	0.077804 (rank : 342)	θ value	θ > 10 (rank : 430)
Query Neighborhood Hits	162	Target Neighborhood Hits	213	Shared Neighborhood Hits	71
SwissProt Accessions	Q5DID0, Q5DIC9, Q6LA40, Q6LA41, Q8N216	Gene names	UMODL1
Domain Architecture	No domain graphic available
Description	Uromodulin-like 1 precursor (Olfactorin).

LAMB3_MOUSE
NC score	0.077580 (rank : 343)	θ value	θ > 10 (rank : 299)
Query Neighborhood Hits	162	Target Neighborhood Hits	444	Shared Neighborhood Hits	85
SwissProt Accessions	Q61087	Gene names	Lamb3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Kalinin B1 chain).

MATN1_HUMAN
NC score	0.077401 (rank : 344)	θ value	θ > 10 (rank : 334)
Query Neighborhood Hits	162	Target Neighborhood Hits	191	Shared Neighborhood Hits	70
SwissProt Accessions	P21941	Gene names	MATN1, CMP, CRTM
Domain Architecture
Description	Cartilage matrix protein precursor (Matrilin-1).

KRA57_HUMAN
NC score	0.077245 (rank : 345)	θ value	θ > 10 (rank : 272)
Query Neighborhood Hits	162	Target Neighborhood Hits	269	Shared Neighborhood Hits	54
SwissProt Accessions	Q6L8G8, Q701N5	Gene names	KRTAP5-7, KAP5-7, KAP5.3, KRTAP5.3, KRTAP5.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-7 (Keratin-associated protein 5.7) (Ultrahigh sulfur keratin-associated protein 5.7) (Keratin-associated protein 5-3) (Keratin-associated protein 5.3).

NRX2A_HUMAN
NC score	0.077086 (rank : 346)	θ value	θ > 10 (rank : 363)
Query Neighborhood Hits	162	Target Neighborhood Hits	614	Shared Neighborhood Hits	88
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

SORL_MOUSE
NC score	0.076748 (rank : 347)	θ value	θ > 10 (rank : 388)
Query Neighborhood Hits	162	Target Neighborhood Hits	439	Shared Neighborhood Hits	81
SwissProt Accessions	O88307, O54711, O70581	Gene names	Sorl1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (Gp250).

SSPO_MOUSE
NC score	0.076478 (rank : 348)	θ value	θ > 10 (rank : 392)
Query Neighborhood Hits	162	Target Neighborhood Hits	800	Shared Neighborhood Hits	107
SwissProt Accessions	Q8CG65	Gene names	Sspo
Domain Architecture	No domain graphic available
Description	SCO-spondin precursor.

PGH1_HUMAN
NC score	0.076226 (rank : 349)	θ value	θ > 10 (rank : 379)
Query Neighborhood Hits	162	Target Neighborhood Hits	91	Shared Neighborhood Hits	61
SwissProt Accessions	P23219, Q15122	Gene names	PTGS1, COX1
Domain Architecture
Description	Prostaglandin G/H synthase 1 precursor (EC 1.14.99.1) (Cyclooxygenase- 1) (COX-1) (Prostaglandin-endoperoxide synthase 1) (Prostaglandin H2 synthase 1) (PGH synthase 1) (PGHS-1) (PHS 1).

LRP5_HUMAN
NC score	0.076193 (rank : 350)	θ value	θ > 10 (rank : 320)
Query Neighborhood Hits	162	Target Neighborhood Hits	224	Shared Neighborhood Hits	65
SwissProt Accessions	O75197, Q96TD6, Q9UP66	Gene names	LRP5, LRP7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor.

PCSK5_MOUSE
NC score	0.075976 (rank : 351)	θ value	θ > 10 (rank : 371)
Query Neighborhood Hits	162	Target Neighborhood Hits	613	Shared Neighborhood Hits	100
SwissProt Accessions	Q04592, Q62040	Gene names	Pcsk5
Domain Architecture
Description	Proprotein convertase subtilisin/kexin type 5 precursor (EC 3.4.21.-) (Proprotein convertase PC5) (Subtilisin/kexin-like protease PC5) (PC6) (Subtilisin-like proprotein convertase 6) (SPC6).

TSP2_HUMAN
NC score	0.075897 (rank : 352)	θ value	θ > 10 (rank : 424)
Query Neighborhood Hits	162	Target Neighborhood Hits	359	Shared Neighborhood Hits	95
SwissProt Accessions	P35442	Gene names	THBS2, TSP2
Domain Architecture
Description	Thrombospondin-2 precursor.

NRG4_HUMAN
NC score	0.075682 (rank : 353)	θ value	θ > 10 (rank : 360)
Query Neighborhood Hits	162	Target Neighborhood Hits	85	Shared Neighborhood Hits	54
SwissProt Accessions	Q8WWG1	Gene names	NRG4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

KR10C_HUMAN
NC score	0.075656 (rank : 354)	θ value	θ > 10 (rank : 256)
Query Neighborhood Hits	162	Target Neighborhood Hits	219	Shared Neighborhood Hits	57
SwissProt Accessions	P60413	Gene names	KRTAP10-12, KAP10.12, KAP18-12, KRTAP10.12, KRTAP18-12, KRTAP18.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-12 (Keratin-associated protein 10.12) (High sulfur keratin-associated protein 10.12) (Keratin-associated protein 18-12) (Keratin-associated protein 18.12).

CNTP1_HUMAN
NC score	0.075528 (rank : 355)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	162	Target Neighborhood Hits	196	Shared Neighborhood Hits	91
SwissProt Accessions	P78357	Gene names	CNTNAP1, CASPR, NRXN4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (p190).

LYAM1_MOUSE
NC score	0.075454 (rank : 356)	θ value	θ > 10 (rank : 326)
Query Neighborhood Hits	162	Target Neighborhood Hits	332	Shared Neighborhood Hits	102
SwissProt Accessions	P18337	Gene names	Sell, Lnhr, Ly-22
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Lymphocyte antigen 22) (Ly-22) (Lymphocyte surface MEL-14 antigen) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

ITB5_HUMAN
NC score	0.075191 (rank : 357)	θ value	θ > 10 (rank : 238)
Query Neighborhood Hits	162	Target Neighborhood Hits	310	Shared Neighborhood Hits	96
SwissProt Accessions	P18084	Gene names	ITGB5
Domain Architecture
Description	Integrin beta-5 precursor.

KRA55_HUMAN
NC score	0.074667 (rank : 358)	θ value	θ > 10 (rank : 271)
Query Neighborhood Hits	162	Target Neighborhood Hits	257	Shared Neighborhood Hits	55
SwissProt Accessions	Q701N2	Gene names	KRTAP5-5, KAP5-11, KAP5.5, KRTAP5-11, KRTAP5.11, KRTAP5.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-5 (Keratin-associated protein 5.5) (Ultrahigh sulfur keratin-associated protein 5.5) (Keratin-associated protein 5-11) (Keratin-associated protein 5.11).

ITB4_HUMAN
NC score	0.074524 (rank : 359)	θ value	θ > 10 (rank : 237)
Query Neighborhood Hits	162	Target Neighborhood Hits	458	Shared Neighborhood Hits	95
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

ITB7_MOUSE
NC score	0.074456 (rank : 360)	θ value	θ > 10 (rank : 243)
Query Neighborhood Hits	162	Target Neighborhood Hits	277	Shared Neighborhood Hits	86
SwissProt Accessions	P26011, Q3U2M1, Q64656	Gene names	Itgb7
Domain Architecture
Description	Integrin beta-7 precursor (Integrin beta-P) (M290 IEL antigen).

LRP5_MOUSE
NC score	0.073963 (rank : 361)	θ value	θ > 10 (rank : 321)
Query Neighborhood Hits	162	Target Neighborhood Hits	236	Shared Neighborhood Hits	69
SwissProt Accessions	Q91VN0, O88883, Q9R208	Gene names	Lrp5, Lrp7
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 5 precursor (LRP7) (Lr3).

KR171_HUMAN
NC score	0.073867 (rank : 362)	θ value	θ > 10 (rank : 257)
Query Neighborhood Hits	162	Target Neighborhood Hits	144	Shared Neighborhood Hits	40
SwissProt Accessions	Q9BYP8	Gene names	KRTAP17-1, KAP17.1, KRTAP16.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 17-1 (Keratin-associated protein 16.1).

CNTP1_MOUSE
NC score	0.073534 (rank : 363)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	162	Target Neighborhood Hits	183	Shared Neighborhood Hits	89
SwissProt Accessions	O54991	Gene names	Cntnap1, Nrxn4
Domain Architecture
Description	Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (Paranodin) (NCP1) (MHDNIV).

LRP6_HUMAN
NC score	0.073371 (rank : 364)	θ value	θ > 10 (rank : 322)
Query Neighborhood Hits	162	Target Neighborhood Hits	235	Shared Neighborhood Hits	70
SwissProt Accessions	O75581	Gene names	LRP6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

SORL_HUMAN
NC score	0.073191 (rank : 365)	θ value	θ > 10 (rank : 387)
Query Neighborhood Hits	162	Target Neighborhood Hits	440	Shared Neighborhood Hits	77
SwissProt Accessions	Q92673, Q92856	Gene names	SORL1
Domain Architecture
Description	Sortilin-related receptor precursor (Sorting protein-related receptor containing LDLR class A repeats) (SorLA) (SorLA-1) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11).

TSP2_MOUSE
NC score	0.073184 (rank : 366)	θ value	θ > 10 (rank : 425)
Query Neighborhood Hits	162	Target Neighborhood Hits	352	Shared Neighborhood Hits	96
SwissProt Accessions	Q03350	Gene names	Thbs2, Tsp2
Domain Architecture
Description	Thrombospondin-2 precursor.

CRAC1_MOUSE
NC score	0.073159 (rank : 367)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	162	Target Neighborhood Hits	112	Shared Neighborhood Hits	52
SwissProt Accessions	Q8R555, Q3UF32, Q8BMF1, Q8R3V8	Gene names	Crtac1, Aspic1, Cep68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (CRTAC1-B protein) (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

ITB1_MOUSE
NC score	0.073128 (rank : 368)	θ value	θ > 10 (rank : 232)
Query Neighborhood Hits	162	Target Neighborhood Hits	283	Shared Neighborhood Hits	83
SwissProt Accessions	P09055	Gene names	Itgb1
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

PHXR5_MOUSE
NC score	0.072848 (rank : 369)	θ value	θ > 10 (rank : 380)
Query Neighborhood Hits	162	Target Neighborhood Hits	102	Shared Neighborhood Hits	40
SwissProt Accessions	P08399	Gene names	Phxr5, Per
Domain Architecture	No domain graphic available
Description	Per-hexamer repeat protein 5.

NRG4_MOUSE
NC score	0.072783 (rank : 370)	θ value	θ > 10 (rank : 361)
Query Neighborhood Hits	162	Target Neighborhood Hits	79	Shared Neighborhood Hits	50
SwissProt Accessions	Q9WTX4	Gene names	Nrg4
Domain Architecture	No domain graphic available
Description	Pro-neuregulin-4, membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)].

CRAC1_HUMAN
NC score	0.072739 (rank : 371)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	162	Target Neighborhood Hits	111	Shared Neighborhood Hits	51
SwissProt Accessions	Q9NQ79, Q8N4H6, Q8TE52, Q9NQ78, Q9NQ80, Q9NW46	Gene names	CRTAC1, ASPIC1, CEP68
Domain Architecture	No domain graphic available
Description	Cartilage acidic protein 1 precursor (Chondrocyte expressed protein 68 kDa) (CEP-68) (ASPIC).

LRP6_MOUSE
NC score	0.072618 (rank : 372)	θ value	θ > 10 (rank : 323)
Query Neighborhood Hits	162	Target Neighborhood Hits	232	Shared Neighborhood Hits	70
SwissProt Accessions	O88572	Gene names	Lrp6
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 6 precursor.

LAMA3_MOUSE
NC score	0.072134 (rank : 373)	θ value	θ > 10 (rank : 289)
Query Neighborhood Hits	162	Target Neighborhood Hits	859	Shared Neighborhood Hits	107
SwissProt Accessions	Q61789, O08751, Q61788, Q61966, Q9JHQ7	Gene names	Lama3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Nicein subunit alpha).

KRA94_HUMAN
NC score	0.071898 (rank : 374)	θ value	θ > 10 (rank : 277)
Query Neighborhood Hits	162	Target Neighborhood Hits	204	Shared Neighborhood Hits	43
SwissProt Accessions	Q9BYQ2	Gene names	KRTAP9-4, KAP9.4, KRTAP9.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4).

LYAM1_HUMAN
NC score	0.071632 (rank : 375)	θ value	θ > 10 (rank : 325)
Query Neighborhood Hits	162	Target Neighborhood Hits	315	Shared Neighborhood Hits	101
SwissProt Accessions	P14151, P15023	Gene names	SELL, LNHR, LYAM1
Domain Architecture
Description	L-selectin precursor (Lymph node homing receptor) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte surface antigen Leu-8) (TQ1) (gp90-MEL) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (CD62L antigen).

ITB3_HUMAN
NC score	0.071323 (rank : 376)	θ value	θ > 10 (rank : 235)
Query Neighborhood Hits	162	Target Neighborhood Hits	325	Shared Neighborhood Hits	94
SwissProt Accessions	P05106, O15495, Q13413, Q14648, Q16499	Gene names	ITGB3, GP3A
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

CRIM1_HUMAN
NC score	0.071303 (rank : 377)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	162	Target Neighborhood Hits	362	Shared Neighborhood Hits	68
SwissProt Accessions	Q9NZV1, Q59GH0, Q7LCQ5, Q9H318	Gene names	CRIM1
Domain Architecture	No domain graphic available
Description	Cysteine-rich motor neuron 1 protein precursor (CRIM-1) (Cysteine-rich repeat-containing protein S52).

KRA54_HUMAN
NC score	0.070940 (rank : 378)	θ value	θ > 10 (rank : 270)
Query Neighborhood Hits	162	Target Neighborhood Hits	270	Shared Neighborhood Hits	53
SwissProt Accessions	Q6L8H1	Gene names	KRTAP5-4, KAP5.4, KRTAP5.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-4 (Keratin-associated protein 5.4) (Ultrahigh sulfur keratin-associated protein 5.4).

KRA93_HUMAN
NC score	0.070807 (rank : 379)	θ value	θ > 10 (rank : 276)
Query Neighborhood Hits	162	Target Neighborhood Hits	203	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BYQ3	Gene names	KRTAP9-3, KAP9.3, KRTAP9.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-3 (Keratin-associated protein 9.3) (Ultrahigh sulfur keratin-associated protein 9.3).

ITB1_HUMAN
NC score	0.070628 (rank : 380)	θ value	θ > 10 (rank : 231)
Query Neighborhood Hits	162	Target Neighborhood Hits	298	Shared Neighborhood Hits	82
SwissProt Accessions	P05556, P78466, P78467, Q13089, Q13090, Q13091, Q13212, Q14622, Q14647	Gene names	ITGB1, FNRB
Domain Architecture
Description	Integrin beta-1 precursor (Fibronectin receptor subunit beta) (Integrin VLA-4 subunit beta) (CD29 antigen).

KRA44_HUMAN
NC score	0.070267 (rank : 381)	θ value	θ > 10 (rank : 264)
Query Neighborhood Hits	162	Target Neighborhood Hits	162	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BYR3	Gene names	KRTAP4-4, KAP4.4, KRTAP4.4
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-4 (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.4).

USH2A_MOUSE
NC score	0.070160 (rank : 382)	θ value	θ > 10 (rank : 435)
Query Neighborhood Hits	162	Target Neighborhood Hits	626	Shared Neighborhood Hits	92
SwissProt Accessions	Q2QI47, Q9JLP3	Gene names	Ush2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein homolog) (Usher syndrome type IIa protein homolog).

KR10B_HUMAN
NC score	0.069796 (rank : 383)	θ value	θ > 10 (rank : 255)
Query Neighborhood Hits	162	Target Neighborhood Hits	269	Shared Neighborhood Hits	59
SwissProt Accessions	P60412	Gene names	KRTAP10-11, KAP10.11, KAP18-11, KRTAP10.11, KRTAP18-11, KRTAP18.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-11 (Keratin-associated protein 10.11) (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11).

LAMB3_HUMAN
NC score	0.069403 (rank : 384)	θ value	θ > 10 (rank : 298)
Query Neighborhood Hits	162	Target Neighborhood Hits	461	Shared Neighborhood Hits	77
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

USH2A_HUMAN
NC score	0.069121 (rank : 385)	θ value	θ > 10 (rank : 434)
Query Neighborhood Hits	162	Target Neighborhood Hits	600	Shared Neighborhood Hits	89
SwissProt Accessions	O75445, Q5VVM9, Q6S362, Q9NS27	Gene names	USH2A
Domain Architecture	No domain graphic available
Description	Usherin precursor (Usher syndrome type-2A protein) (Usher syndrome type IIa protein).

SMDF_HUMAN
NC score	0.069024 (rank : 386)	θ value	θ > 10 (rank : 386)
Query Neighborhood Hits	162	Target Neighborhood Hits	117	Shared Neighborhood Hits	53
SwissProt Accessions	Q15491	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture	No domain graphic available
Description	Neuregulin-1, sensory and motor neuron-derived factor isoform.

KRA98_HUMAN
NC score	0.068969 (rank : 387)	θ value	θ > 10 (rank : 278)
Query Neighborhood Hits	162	Target Neighborhood Hits	185	Shared Neighborhood Hits	42
SwissProt Accessions	Q9BYQ0	Gene names	KRTAP9-8, KAP9.8, KRTAP9.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-8 (Keratin-associated protein 9.8) (Ultrahigh sulfur keratin-associated protein 9.8).

ITB2_MOUSE
NC score	0.068894 (rank : 388)	θ value	θ > 10 (rank : 234)
Query Neighborhood Hits	162	Target Neighborhood Hits	326	Shared Neighborhood Hits	94
SwissProt Accessions	P11835, Q64482	Gene names	Itgb2
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/P150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

ITB2_HUMAN
NC score	0.068414 (rank : 389)	θ value	θ > 10 (rank : 233)
Query Neighborhood Hits	162	Target Neighborhood Hits	282	Shared Neighborhood Hits	87
SwissProt Accessions	P05107, Q16418	Gene names	ITGB2, CD18
Domain Architecture
Description	Integrin beta-2 precursor (Cell surface adhesion glycoproteins LFA- 1/CR3/p150,95 subunit beta) (Complement receptor C3 subunit beta) (CD18 antigen).

PGCA_HUMAN
NC score	0.067684 (rank : 390)	θ value	θ > 10 (rank : 378)
Query Neighborhood Hits	162	Target Neighborhood Hits	821	Shared Neighborhood Hits	104
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

LAMA3_HUMAN
NC score	0.067221 (rank : 391)	θ value	θ > 10 (rank : 288)
Query Neighborhood Hits	162	Target Neighborhood Hits	760	Shared Neighborhood Hits	100
SwissProt Accessions	Q16787, Q13679, Q13680, Q96TG0	Gene names	LAMA3
Domain Architecture
Description	Laminin alpha-3 chain precursor (Epiligrin 170 kDa subunit) (E170) (Nicein subunit alpha).

TPA_MOUSE
NC score	0.066904 (rank : 392)	θ value	θ > 10 (rank : 415)
Query Neighborhood Hits	162	Target Neighborhood Hits	335	Shared Neighborhood Hits	95
SwissProt Accessions	P11214, Q91VP2	Gene names	Plat
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

LCE1B_HUMAN
NC score	0.066889 (rank : 393)	θ value	θ > 10 (rank : 306)
Query Neighborhood Hits	162	Target Neighborhood Hits	58	Shared Neighborhood Hits	17
SwissProt Accessions	Q5T7P3	Gene names	LCE1B, LEP2, SPRL2A
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1B (Late envelope protein 2) (Small proline-rich-like epidermal differentiation complex protein 2A).

ITB3_MOUSE
NC score	0.066183 (rank : 394)	θ value	θ > 10 (rank : 236)
Query Neighborhood Hits	162	Target Neighborhood Hits	319	Shared Neighborhood Hits	86
SwissProt Accessions	O54890	Gene names	Itgb3
Domain Architecture
Description	Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD61 antigen).

TENN_MOUSE
NC score	0.065197 (rank : 395)	θ value	θ > 10 (rank : 408)
Query Neighborhood Hits	162	Target Neighborhood Hits	484	Shared Neighborhood Hits	83
SwissProt Accessions	Q80Z71	Gene names	Tnn
Domain Architecture
Description	Tenascin-N precursor (TN-N).

KRA13_HUMAN
NC score	0.064984 (rank : 396)	θ value	θ > 10 (rank : 262)
Query Neighborhood Hits	162	Target Neighborhood Hits	144	Shared Neighborhood Hits	37
SwissProt Accessions	Q8IUG1, Q07628, Q8IUG0, Q9BYS2	Gene names	KRTAP1-3, B2B, KAP1.2, KAP1.3, KAP1.8, KAP1.9, KRATP1.9, KRTAP1.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-3 (Keratin-associated protein 1.8) (Keratin-associated protein 1.9).

NRG1_HUMAN
NC score	0.064739 (rank : 397)	θ value	θ > 10 (rank : 358)
Query Neighborhood Hits	162	Target Neighborhood Hits	285	Shared Neighborhood Hits	63
SwissProt Accessions	Q02297, O14667, P98202, Q02298, Q02299, Q07110, Q07111, Q12779, Q12780, Q12781, Q12782, Q12783, Q12784, Q7RTV9, Q7RTW0, Q7RTW1, Q7RTW2, Q8NFN1, Q8NFN2, Q8NFN3, Q9UPE3	Gene names	NRG1, GGF, HGL, HRGA, NDF, SMDF
Domain Architecture
Description	Pro-neuregulin-1, membrane-bound isoform precursor (Pro-NRG1) [Contains: Neuregulin-1 (Neu differentiation factor) (Heregulin) (HRG) (Breast cancer cell differentiation factor p45) (Acetylcholine receptor-inducing activity) (ARIA) (Sensory and motor neuron-derived factor) (Glial growth factor)].

TPA_HUMAN
NC score	0.064330 (rank : 398)	θ value	θ > 10 (rank : 414)
Query Neighborhood Hits	162	Target Neighborhood Hits	324	Shared Neighborhood Hits	93
SwissProt Accessions	P00750, Q15103, Q7Z7N2, Q86YK8, Q9BU99	Gene names	PLAT
Domain Architecture
Description	Tissue-type plasminogen activator precursor (EC 3.4.21.68) (tPA) (t- PA) (t-plasminogen activator) (Alteplase) (Reteplase) [Contains: Tissue-type plasminogen activator chain A; Tissue-type plasminogen activator chain B].

LAMA4_MOUSE
NC score	0.063628 (rank : 399)	θ value	θ > 10 (rank : 291)
Query Neighborhood Hits	162	Target Neighborhood Hits	584	Shared Neighborhood Hits	93
SwissProt Accessions	P97927, O88785, P70409	Gene names	Lama4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

LAMA4_HUMAN
NC score	0.062518 (rank : 400)	θ value	θ > 10 (rank : 290)
Query Neighborhood Hits	162	Target Neighborhood Hits	708	Shared Neighborhood Hits	96
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

KR414_HUMAN
NC score	0.061994 (rank : 401)	θ value	θ > 10 (rank : 259)
Query Neighborhood Hits	162	Target Neighborhood Hits	199	Shared Neighborhood Hits	41
SwissProt Accessions	Q9BYQ6	Gene names	KRTAP4-14, KAP4.14, KRTAP4.14
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-14 (Keratin-associated protein 4.14) (Ultrahigh sulfur keratin-associated protein 4.14).

LRP10_MOUSE
NC score	0.061261 (rank : 402)	θ value	θ > 10 (rank : 312)
Query Neighborhood Hits	162	Target Neighborhood Hits	169	Shared Neighborhood Hits	31
SwissProt Accessions	Q7TQH7, Q7TS95, Q921T0, Q9EPE8	Gene names	Lrp10, Lrp9
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

RECK_HUMAN
NC score	0.060230 (rank : 403)	θ value	5.27518 (rank : 144)
Query Neighborhood Hits	162	Target Neighborhood Hits	189	Shared Neighborhood Hits	51
SwissProt Accessions	O95980, Q8WX37	Gene names	RECK
Domain Architecture
Description	Reversion-inducing cysteine-rich protein with Kazal motifs precursor (hRECK) (Suppressor of tumorigenicity 15) (ST15).

TENN_HUMAN
NC score	0.060065 (rank : 404)	θ value	θ > 10 (rank : 407)
Query Neighborhood Hits	162	Target Neighborhood Hits	453	Shared Neighborhood Hits	84
SwissProt Accessions	Q9UQP3, Q5R360	Gene names	TNN
Domain Architecture
Description	Tenascin-N precursor (TN-N).

KRA45_HUMAN
NC score	0.059926 (rank : 405)	θ value	θ > 10 (rank : 265)
Query Neighborhood Hits	162	Target Neighborhood Hits	194	Shared Neighborhood Hits	39
SwissProt Accessions	Q9BYR2	Gene names	KRTAP4-5, KAP4.5, KRTAP4.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-5 (Keratin-associated protein 4.5) (Ultrahigh sulfur keratin-associated protein 4.5).

KR511_HUMAN
NC score	0.059867 (rank : 406)	θ value	θ > 10 (rank : 260)
Query Neighborhood Hits	162	Target Neighborhood Hits	231	Shared Neighborhood Hits	43
SwissProt Accessions	Q6L8G4	Gene names	KRTAP5-11, KAP5.11, KRTAP5.11
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-11 (Keratin-associated protein 5.11) (Ultrahigh sulfur keratin-associated protein 5.11).

EMR4_MOUSE
NC score	0.059436 (rank : 407)	θ value	θ > 10 (rank : 214)
Query Neighborhood Hits	162	Target Neighborhood Hits	191	Shared Neighborhood Hits	68
SwissProt Accessions	Q91ZE5, Q3U1I7, Q8BYX0, Q8VIM3	Gene names	Emr4
Domain Architecture
Description	EGF-like module-containing mucin-like hormone receptor-like 4 precursor (EGF-like module-containing mucin-like receptor EMR4) (F4/80-like-receptor) (Seven-span membrane protein FIRE).

LCE1C_HUMAN
NC score	0.059222 (rank : 408)	θ value	θ > 10 (rank : 307)
Query Neighborhood Hits	162	Target Neighborhood Hits	65	Shared Neighborhood Hits	14
SwissProt Accessions	Q5T751	Gene names	LCE1C, LEP3
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1C (Late envelope protein 3).

CO8B_MOUSE
NC score	0.059077 (rank : 409)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	162	Target Neighborhood Hits	224	Shared Neighborhood Hits	62
SwissProt Accessions	Q8BH35, Q4VAH1, Q8CHJ5, Q8CHJ6, Q8VC14	Gene names	C8b
Domain Architecture	No domain graphic available
Description	Complement component C8 beta chain precursor (Complement component 8 subunit beta).

KRA99_HUMAN
NC score	0.058813 (rank : 410)	θ value	θ > 10 (rank : 279)
Query Neighborhood Hits	162	Target Neighborhood Hits	173	Shared Neighborhood Hits	43
SwissProt Accessions	Q9BYP9	Gene names	KRTAP9-9, KAP9.9, KRTAP9.9
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-9 (Keratin-associated protein 9.9) (Ultrahigh sulfur keratin-associated protein 9.9).

TECTA_MOUSE
NC score	0.058381 (rank : 411)	θ value	θ > 10 (rank : 402)
Query Neighborhood Hits	162	Target Neighborhood Hits	244	Shared Neighborhood Hits	76
SwissProt Accessions	O08523	Gene names	Tecta
Domain Architecture
Description	Alpha-tectorin precursor.

CORIN_HUMAN
NC score	0.058346 (rank : 412)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	162	Target Neighborhood Hits	453	Shared Neighborhood Hits	75
SwissProt Accessions	Q9Y5Q5, Q9UHY2	Gene names	CORIN, CRN, TMPRSS10
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Heart-specific serine proteinase ATC2) (Transmembrane protease, serine 10).

KR103_HUMAN
NC score	0.057902 (rank : 413)	θ value	θ > 10 (rank : 247)
Query Neighborhood Hits	162	Target Neighborhood Hits	212	Shared Neighborhood Hits	51
SwissProt Accessions	P60369, Q70LJ4	Gene names	KRTAP10-3, KAP10.3, KAP18-3, KRTAP10.3, KRTAP18-3, KRTAP18.3
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-3 (Keratin-associated protein 10.3) (High sulfur keratin-associated protein 10.3) (Keratin-associated protein 18-3) (Keratin-associated protein 18.3).

KRA92_HUMAN
NC score	0.057840 (rank : 414)	θ value	θ > 10 (rank : 275)
Query Neighborhood Hits	162	Target Neighborhood Hits	198	Shared Neighborhood Hits	37
SwissProt Accessions	Q9BYQ4	Gene names	KRTAP9-2, KAP9.2, KRTAP9.2
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 9-2 (Keratin-associated protein 9.2) (Ultrahigh sulfur keratin-associated protein 9.2).

KRA15_HUMAN
NC score	0.057568 (rank : 415)	θ value	θ > 10 (rank : 263)
Query Neighborhood Hits	162	Target Neighborhood Hits	126	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BYS1, Q52LP6	Gene names	KRTAP1-5, KAP1.5, KRTAP1.5
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-5 (Keratin-associated protein 1.5) (High sulfur keratin-associated protein 1.5).

KR10A_HUMAN
NC score	0.057430 (rank : 416)	θ value	θ > 10 (rank : 254)
Query Neighborhood Hits	162	Target Neighborhood Hits	232	Shared Neighborhood Hits	53
SwissProt Accessions	P60014	Gene names	KRTAP10-10, KAP10.10, KAP18-10, KRTAP10.10, KRTAP18-1, KRTAP18.10
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 10-10 (Keratin-associated protein 10.10) (High sulfur keratin-associated protein 10.10) (Keratin-associated protein 18-10) (Keratin-associated protein 18.10).

VASN_HUMAN
NC score	0.057092 (rank : 417)	θ value	1.38821 (rank : 120)
Query Neighborhood Hits	162	Target Neighborhood Hits	449	Shared Neighborhood Hits	84
SwissProt Accessions	Q6EMK4, Q6UXL4, Q6UXL5, Q96CX1	Gene names	VASN, SLITL2
Domain Architecture	No domain graphic available
Description	Vasorin precursor (Protein Slit-like 2).

CO7_HUMAN
NC score	0.057039 (rank : 418)	θ value	1.38821 (rank : 115)
Query Neighborhood Hits	162	Target Neighborhood Hits	278	Shared Neighborhood Hits	66
SwissProt Accessions	P10643, Q6P3T5, Q92489	Gene names	C7
Domain Architecture
Description	Complement component C7 precursor.

FRAS1_HUMAN
NC score	0.056930 (rank : 419)	θ value	θ > 10 (rank : 222)
Query Neighborhood Hits	162	Target Neighborhood Hits	759	Shared Neighborhood Hits	85
SwissProt Accessions	Q86XX4, Q86UZ4, Q8N3U9, Q8NAU7, Q96JW7, Q9H6N9, Q9P228	Gene names	FRAS1, KIAA1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

TMPS6_HUMAN
NC score	0.056507 (rank : 420)	θ value	θ > 10 (rank : 412)
Query Neighborhood Hits	162	Target Neighborhood Hits	338	Shared Neighborhood Hits	63
SwissProt Accessions	Q8IU80, Q5TI06, Q6UXD8, Q8IUE2, Q8IXV8	Gene names	TMPRSS6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

FRAS1_MOUSE
NC score	0.055020 (rank : 421)	θ value	θ > 10 (rank : 223)
Query Neighborhood Hits	162	Target Neighborhood Hits	747	Shared Neighborhood Hits	82
SwissProt Accessions	Q80T14, Q80TC7, Q811H8, Q8BPZ4	Gene names	Fras1, Kiaa1500
Domain Architecture	No domain graphic available
Description	Extracellular matrix protein FRAS1 precursor.

KR412_HUMAN
NC score	0.054972 (rank : 422)	θ value	θ > 10 (rank : 258)
Query Neighborhood Hits	162	Target Neighborhood Hits	178	Shared Neighborhood Hits	32
SwissProt Accessions	Q9BQ66, Q495I0	Gene names	KRTAP4-12, KAP4.12, KRTAP4.12
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-12 (Keratin-associated protein 4.12) (Ultrahigh sulfur keratin-associated protein 4.12).

KRA11_HUMAN
NC score	0.054922 (rank : 423)	θ value	θ > 10 (rank : 261)
Query Neighborhood Hits	162	Target Neighborhood Hits	155	Shared Neighborhood Hits	36
SwissProt Accessions	Q07627, Q96S60, Q96S67	Gene names	KRTAP1-1, B2A, KAP1.1, KAP1.6, KAP1.7, KRTAP1.1
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 1-1 (Keratin-associated protein 1.1) (High sulfur keratin-associated protein 1.1) (Keratin-associated protein 1.6) (Keratin-associated protein 1.7).

ITB8_HUMAN
NC score	0.053870 (rank : 424)	θ value	θ > 10 (rank : 244)
Query Neighborhood Hits	162	Target Neighborhood Hits	280	Shared Neighborhood Hits	78
SwissProt Accessions	P26012	Gene names	ITGB8
Domain Architecture
Description	Integrin beta-8 precursor.

LRP10_HUMAN
NC score	0.053696 (rank : 425)	θ value	θ > 10 (rank : 311)
Query Neighborhood Hits	162	Target Neighborhood Hits	197	Shared Neighborhood Hits	28
SwissProt Accessions	Q7Z4F1, O95882, Q86T02, Q8NCZ4, Q9HC42, Q9UG33	Gene names	LRP10
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 10 precursor.

VWF_HUMAN
NC score	0.053287 (rank : 426)	θ value	θ > 10 (rank : 436)
Query Neighborhood Hits	162	Target Neighborhood Hits	396	Shared Neighborhood Hits	71
SwissProt Accessions	P04275	Gene names	VWF, F8VWF
Domain Architecture
Description	von Willebrand factor precursor (vWF) [Contains: von Willebrand antigen 2 (von Willebrand antigen II)].

NFX1_HUMAN
NC score	0.053284 (rank : 427)	θ value	θ > 10 (rank : 357)
Query Neighborhood Hits	162	Target Neighborhood Hits	405	Shared Neighborhood Hits	52
SwissProt Accessions	Q12986	Gene names	NFX1
Domain Architecture
Description	Transcriptional repressor NF-X1 (EC 6.3.2.-) (Nuclear transcription factor, X box-binding, 1).

KRA47_HUMAN
NC score	0.053209 (rank : 428)	θ value	θ > 10 (rank : 266)
Query Neighborhood Hits	162	Target Neighborhood Hits	204	Shared Neighborhood Hits	38
SwissProt Accessions	Q9BYR0	Gene names	KRTAP4-7, KAP4.7, KRTAP4.7
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 4-7 (Keratin-associated protein 4.7) (Ultrahigh sulfur keratin-associated protein 4.7).

TMPS6_MOUSE
NC score	0.052926 (rank : 429)	θ value	θ > 10 (rank : 413)
Query Neighborhood Hits	162	Target Neighborhood Hits	341	Shared Neighborhood Hits	64
SwissProt Accessions	Q9DBI0, Q6PF94	Gene names	Tmprss6
Domain Architecture
Description	Transmembrane protease, serine 6 (EC 3.4.21.-) (Matriptase-2).

ASTN_HUMAN
NC score	0.052815 (rank : 430)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	162	Target Neighborhood Hits	105	Shared Neighborhood Hits	44
SwissProt Accessions	O14525, O60799, Q5W0V7, Q5W0V8	Gene names	ASTN, ASTN1, KIAA0289
Domain Architecture	No domain graphic available
Description	Astrotactin-1 precursor.

LCE1E_HUMAN
NC score	0.052681 (rank : 431)	θ value	θ > 10 (rank : 308)
Query Neighborhood Hits	162	Target Neighborhood Hits	53	Shared Neighborhood Hits	10
SwissProt Accessions	Q5T753	Gene names	LCE1E, LEP5
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 1E (Late envelope protein 5).

KRA52_HUMAN
NC score	0.052621 (rank : 432)	θ value	θ > 10 (rank : 268)
Query Neighborhood Hits	162	Target Neighborhood Hits	236	Shared Neighborhood Hits	43
SwissProt Accessions	Q701N4	Gene names	KRTAP5-2, KAP5-8, KAP5.2, KRTAP5-8, KRTAP5.2, KRTAP5.8
Domain Architecture	No domain graphic available
Description	Keratin-associated protein 5-2 (Keratin-associated protein 5.2) (Ultrahigh sulfur keratin-associated protein 5.2) (Keratin-associated protein 5-8) (Keratin-associated protein 5.8).

CORIN_MOUSE
NC score	0.052537 (rank : 433)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	162	Target Neighborhood Hits	451	Shared Neighborhood Hits	76
SwissProt Accessions	Q9Z319	Gene names	Corin, Crn, Lrp4
Domain Architecture
Description	Atrial natriuteric peptide-converting enzyme (EC 3.4.21.-) (pro-ANP- converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4).

MUC5B_HUMAN
NC score	0.051161 (rank : 434)	θ value	θ > 10 (rank : 347)
Query Neighborhood Hits	162	Target Neighborhood Hits	1020	Shared Neighborhood Hits	90
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

ACS2L_MOUSE
NC score	0.007809 (rank : 435)	θ value	6.88961 (rank : 145)
Query Neighborhood Hits	162	Target Neighborhood Hits	35	Shared Neighborhood Hits	2
SwissProt Accessions	Q99NB1, Q8K0M6	Gene names	Acss1, Acas2, Acas2l
Domain Architecture
Description	Acetyl-coenzyme A synthetase 2-like, mitochondrial precursor (EC 6.2.1.1) (Acetate--CoA ligase 2) (Acetyl-CoA synthetase 2) (AceCS2) (Acyl-CoA synthetase short-chain family member 1).

CATW_MOUSE
NC score	0.006899 (rank : 436)	θ value	5.27518 (rank : 139)
Query Neighborhood Hits	162	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	P56203	Gene names	Ctsw
Domain Architecture
Description	Cathepsin W precursor (EC 3.4.22.-) (Lymphopain).