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Network neighborhood for query Sequence : ACS2L_MOUSE

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ACS2L_MOUSE
SwissProt Accessions	Q99NB1, Q8K0M6	Gene names	Acss1, Acas2, Acas2l
Domain Architecture
Description	Acetyl-coenzyme A synthetase 2-like, mitochondrial precursor (EC 6.2.1.1) (Acetate--CoA ligase 2) (Acetyl-CoA synthetase 2) (AceCS2) (Acyl-CoA synthetase short-chain family member 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ACS2L_HUMAN
θ value	0 (rank : 1)	NC score	0.997742 (rank : 2)
Query Neighborhood Hits	35	Target Neighborhood Hits	30	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NUB1, Q5TF42, Q8IV99, Q8N234, Q96JI1, Q96JX6, Q9NU28	Gene names	ACSS1, ACAS2L, KIAA1846
Domain Architecture
Description	Acetyl-coenzyme A synthetase 2-like, mitochondrial precursor (EC 6.2.1.1) (Acetate--CoA ligase 2) (Acetyl-CoA synthetase 2) (Acyl- CoA synthetase short-chain family member 1).

ACS2L_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	35	Target Neighborhood Hits	35	Shared Neighborhood Hits	35
SwissProt Accessions	Q99NB1, Q8K0M6	Gene names	Acss1, Acas2, Acas2l
Domain Architecture
Description	Acetyl-coenzyme A synthetase 2-like, mitochondrial precursor (EC 6.2.1.1) (Acetate--CoA ligase 2) (Acetyl-CoA synthetase 2) (AceCS2) (Acyl-CoA synthetase short-chain family member 1).

ACSA_HUMAN
θ value	2.57449e-172 (rank : 3)	NC score	0.967818 (rank : 3)
Query Neighborhood Hits	35	Target Neighborhood Hits	30	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NR19, Q5QPH2, Q96EL0, Q9NQP7, Q9UJ15	Gene names	ACSS2, ACAS2
Domain Architecture
Description	Acetyl-coenzyme A synthetase, cytoplasmic (EC 6.2.1.1) (Acetate--CoA ligase) (Acyl-activating enzyme) (Acetyl-CoA synthetase) (ACS) (AceCS) (Acyl-CoA synthetase short-chain family member 2).

ACSA_MOUSE
θ value	8.57033e-168 (rank : 4)	NC score	0.966652 (rank : 4)
Query Neighborhood Hits	35	Target Neighborhood Hits	27	Shared Neighborhood Hits	20
SwissProt Accessions	Q9QXG4	Gene names	Acss2, Acas2, Acecs1
Domain Architecture
Description	Acetyl-coenzyme A synthetase, cytoplasmic (EC 6.2.1.1) (Acetate--CoA ligase) (Acyl-activating enzyme) (Acetyl-CoA synthetase) (ACS) (AceCS) (Acyl-CoA synthetase short-chain family member 2).

S27A1_HUMAN
θ value	2.60593e-15 (rank : 5)	NC score	0.477921 (rank : 6)
Query Neighborhood Hits	35	Target Neighborhood Hits	27	Shared Neighborhood Hits	23
SwissProt Accessions	Q6PCB7	Gene names	SLC27A1, ACSVL5, FATP1
Domain Architecture	No domain graphic available
Description	Long-chain fatty acid transport protein 1 (EC 6.2.1.-) (Fatty acid transport protein 1) (FATP-1) (Solute carrier family 27 member 1).

S27A1_MOUSE
θ value	2.20605e-14 (rank : 6)	NC score	0.471267 (rank : 8)
Query Neighborhood Hits	35	Target Neighborhood Hits	24	Shared Neighborhood Hits	22
SwissProt Accessions	Q60714	Gene names	Slc27a1, Fatp, Fatp1
Domain Architecture
Description	Long-chain fatty acid transport protein 1 (EC 6.2.1.-) (Fatty acid transport protein 1) (FATP-1) (Solute carrier family 27 member 1).

S27A4_MOUSE
θ value	4.16044e-13 (rank : 7)	NC score	0.474101 (rank : 7)
Query Neighborhood Hits	35	Target Neighborhood Hits	29	Shared Neighborhood Hits	24
SwissProt Accessions	Q91VE0, O88562	Gene names	Slc27a4, Acsvl4, Fatp4
Domain Architecture	No domain graphic available
Description	Long-chain fatty acid transport protein 4 (EC 6.2.1.-) (Fatty acid transport protein 4) (FATP-4) (Solute carrier family 27 member 4).

S27A4_HUMAN
θ value	7.09661e-13 (rank : 8)	NC score	0.479681 (rank : 5)
Query Neighborhood Hits	35	Target Neighborhood Hits	28	Shared Neighborhood Hits	24
SwissProt Accessions	Q6P1M0, O95186	Gene names	SLC27A4, ACSVL4, FATP4
Domain Architecture	No domain graphic available
Description	Long-chain fatty acid transport protein 4 (EC 6.2.1.-) (Fatty acid transport protein 4) (FATP-4) (Solute carrier family 27 member 4).

S27A6_HUMAN
θ value	1.47974e-10 (rank : 9)	NC score	0.419415 (rank : 9)
Query Neighborhood Hits	35	Target Neighborhood Hits	26	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y2P4, Q6IAM5, Q7Z6E6, Q86YF6	Gene names	SLC27A6, ACSVL2, FACVL2, FATP1
Domain Architecture	No domain graphic available
Description	Long-chain fatty acid transport protein 6 (Fatty acid transport protein 6) (FATP-6) (Very long-chain acyl-CoA synthetase homolog 1) (VLCSH1) (hVLCS-H1) (Fatty-acid-coenzyme A ligase, very long-chain 2) (Solute carrier family 27 member 6).

S27A3_HUMAN
θ value	7.1131e-05 (rank : 10)	NC score	0.390334 (rank : 10)
Query Neighborhood Hits	35	Target Neighborhood Hits	38	Shared Neighborhood Hits	24
SwissProt Accessions	Q5K4L6, Q5VUQ7, Q5VUQ8, Q6ZV16, Q8N2X7, Q96SW5, Q9BTJ5, Q9BTY5	Gene names	SLC27A3, ACSVL3, FATP3
Domain Architecture	No domain graphic available
Description	Long-chain fatty acid transport protein 3 (EC 6.2.1.-) (Fatty acid transport protein 3) (FATP-3) (Very long-chain acyl-CoA synthetase homolog 3) (VLCS-3) (Solute carrier family 27 member 3).

S27A2_MOUSE
θ value	0.000786445 (rank : 11)	NC score	0.374517 (rank : 14)
Query Neighborhood Hits	35	Target Neighborhood Hits	27	Shared Neighborhood Hits	21
SwissProt Accessions	O35488, O70550, O88560	Gene names	Slc27a2, Acsvl1, Facvl1, Fatp2, Vlacs, Vlcs
Domain Architecture
Description	Very-long-chain acyl-CoA synthetase (EC 6.2.1.-) (VLCS) (Very-long- chain-fatty-acid-CoA ligase) (VLACS) (THCA-CoA ligase) (Fatty-acid- coenzyme A ligase, very long-chain 1) (Long-chain-fatty-acid--CoA ligase) (EC 6.2.1.3) (Fatty acid transport protein 2) (FATP-2) (Solute carrier family 27 member 2).

S27A2_HUMAN
θ value	0.00102713 (rank : 12)	NC score	0.362446 (rank : 15)
Query Neighborhood Hits	35	Target Neighborhood Hits	30	Shared Neighborhood Hits	24
SwissProt Accessions	O14975	Gene names	SLC27A2, ACSVL1, FACVL1, FATP2, VLACS
Domain Architecture
Description	Very-long-chain acyl-CoA synthetase (EC 6.2.1.-) (VLCS) (Very-long- chain-fatty-acid-CoA ligase) (VLACS) (THCA-CoA ligase) (Fatty-acid- coenzyme A ligase, very long-chain 1) (Long-chain-fatty-acid--CoA ligase) (EC 6.2.1.3) (Fatty acid transport protein 2) (FATP-2) (Solute carrier family 27 member 2).

ACSL4_MOUSE
θ value	0.00134147 (rank : 13)	NC score	0.185515 (rank : 16)
Query Neighborhood Hits	35	Target Neighborhood Hits	32	Shared Neighborhood Hits	23
SwissProt Accessions	Q9QUJ7, Q9JHT4, Q9R0H3	Gene names	Acsl4, Acs4, Facl4
Domain Architecture
Description	Long-chain-fatty-acid--CoA ligase 4 (EC 6.2.1.3) (Long-chain acyl-CoA synthetase 4) (LACS 4) (mACS4).

S27A5_HUMAN
θ value	0.00228821 (rank : 14)	NC score	0.384055 (rank : 11)
Query Neighborhood Hits	35	Target Neighborhood Hits	28	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y2P5	Gene names	SLC27A5, ACSB, ACSVL6, FACVL3, FATP5
Domain Architecture	No domain graphic available
Description	Bile acyl-CoA synthetase (EC 6.2.1.7) (BACS) (Bile acid CoA ligase) (BA-CoA ligase) (BAL) (Cholate--CoA ligase) (Very long-chain acyl-CoA synthetase homolog 2) (VLCSH2) (VLCS-H2) (Very long chain acyl-CoA synthetase-related protein) (VLACS-related) (VLACSR) (Fatty-acid- coenzyme A ligase, very long-chain 3) (Fatty acid transport protein 5) (FATP-5) (Solute carrier family 27 member 5).

ACSL3_HUMAN
θ value	0.0252991 (rank : 15)	NC score	0.159148 (rank : 18)
Query Neighborhood Hits	35	Target Neighborhood Hits	25	Shared Neighborhood Hits	24
SwissProt Accessions	O95573, Q60I92, Q8IUM9	Gene names	ACSL3, ACS3, FACL3, LACS3
Domain Architecture
Description	Long-chain-fatty-acid--CoA ligase 3 (EC 6.2.1.3) (Long-chain acyl-CoA synthetase 3) (LACS 3).

S27A5_MOUSE
θ value	0.0563607 (rank : 16)	NC score	0.382670 (rank : 12)
Query Neighborhood Hits	35	Target Neighborhood Hits	31	Shared Neighborhood Hits	24
SwissProt Accessions	Q4LDG0, O88694, Q91VD5	Gene names	Slc27a5, Acsb, Acsvl6, Fatp5, Vlacsr
Domain Architecture	No domain graphic available
Description	Bile acyl-CoA synthetase (EC 6.2.1.7) (BACS) (Bile acid CoA ligase) (BA-CoA ligase) (BAL) (Cholate--CoA ligase) (Very long chain acyl-CoA synthetase-related protein) (VLACS-related) (VLACSR) (Fatty acid transport protein 5) (FATP-5) (Solute carrier family 27 member 5).

S27A3_MOUSE
θ value	0.0961366 (rank : 17)	NC score	0.375553 (rank : 13)
Query Neighborhood Hits	35	Target Neighborhood Hits	32	Shared Neighborhood Hits	24
SwissProt Accessions	O88561, Q6PAU1, Q8BK70	Gene names	Slc27a3, Acsvl3, Fatp3
Domain Architecture	No domain graphic available
Description	Long-chain fatty acid transport protein 3 (EC 6.2.1.-) (Fatty acid transport protein 3) (FATP-3) (Solute carrier family 27 member 3).

ACSL3_MOUSE
θ value	0.125558 (rank : 18)	NC score	0.141718 (rank : 19)
Query Neighborhood Hits	35	Target Neighborhood Hits	26	Shared Neighborhood Hits	24
SwissProt Accessions	Q9CZW4	Gene names	Acsl3, Acs3, Facl3
Domain Architecture
Description	Long-chain-fatty-acid--CoA ligase 3 (EC 6.2.1.3) (Long-chain acyl-CoA synthetase 3) (LACS 3).

ACSL4_HUMAN
θ value	0.163984 (rank : 19)	NC score	0.165807 (rank : 17)
Query Neighborhood Hits	35	Target Neighborhood Hits	31	Shared Neighborhood Hits	22
SwissProt Accessions	O60488, O60848, O60849	Gene names	ACSL4, ACS4, FACL4, LACS4
Domain Architecture
Description	Long-chain-fatty-acid--CoA ligase 4 (EC 6.2.1.3) (Long-chain acyl-CoA synthetase 4) (LACS 4).

ACSL5_HUMAN
θ value	1.38821 (rank : 20)	NC score	0.108248 (rank : 20)
Query Neighborhood Hits	35	Target Neighborhood Hits	30	Shared Neighborhood Hits	21
SwissProt Accessions	Q9ULC5, Q6UX44, Q9UIU4	Gene names	ACSL5, ACS5, FACL5
Domain Architecture
Description	Long-chain-fatty-acid--CoA ligase 5 (EC 6.2.1.3) (Long-chain acyl-CoA synthetase 5) (LACS 5).

ACSL6_MOUSE
θ value	1.38821 (rank : 21)	NC score	0.096444 (rank : 22)
Query Neighborhood Hits	35	Target Neighborhood Hits	29	Shared Neighborhood Hits	20
SwissProt Accessions	Q91WC3, Q80ZF1	Gene names	Acsl6, Facl6
Domain Architecture
Description	Long-chain-fatty-acid--CoA ligase 6 (EC 6.2.1.3) (Long-chain acyl-CoA synthetase 6) (LACS 6).

KS6A5_MOUSE
θ value	1.81305 (rank : 22)	NC score	0.002598 (rank : 36)
Query Neighborhood Hits	35	Target Neighborhood Hits	854	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C050, Q8CI92	Gene names	Rps6ka5, Msk1
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1) (Nuclear mitogen- and stress-activated protein kinase 1) (90 kDa ribosomal protein S6 kinase 5) (RSK-like protein kinase) (RLSK).

PARG_HUMAN
θ value	3.0926 (rank : 23)	NC score	0.034735 (rank : 27)
Query Neighborhood Hits	35	Target Neighborhood Hits	97	Shared Neighborhood Hits	4
SwissProt Accessions	Q86W56, Q6E4P6, Q6E4P7, Q7Z742, Q9Y4W7	Gene names	PARG
Domain Architecture	No domain graphic available
Description	Poly(ADP-ribose) glycohydrolase (EC 3.2.1.143).

PARG_MOUSE
θ value	3.0926 (rank : 24)	NC score	0.035508 (rank : 26)
Query Neighborhood Hits	35	Target Neighborhood Hits	54	Shared Neighborhood Hits	4
SwissProt Accessions	O88622, Q80YQ6, Q8CB72	Gene names	Parg
Domain Architecture	No domain graphic available
Description	Poly(ADP-ribose) glycohydrolase (EC 3.2.1.143).

SDK1_HUMAN
θ value	3.0926 (rank : 25)	NC score	0.005939 (rank : 34)
Query Neighborhood Hits	35	Target Neighborhood Hits	511	Shared Neighborhood Hits	3
SwissProt Accessions	Q7Z5N4, Q8TEN9, Q8TEP5, Q96N44	Gene names	SDK1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

SYNE2_HUMAN
θ value	3.0926 (rank : 26)	NC score	0.004955 (rank : 35)
Query Neighborhood Hits	35	Target Neighborhood Hits	1323	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

ACSL6_HUMAN
θ value	4.03905 (rank : 27)	NC score	0.090727 (rank : 24)
Query Neighborhood Hits	35	Target Neighborhood Hits	29	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UKU0, O94924, O95829	Gene names	ACSL6, ACS2, FACL6, KIAA0837, LACS5
Domain Architecture
Description	Long-chain-fatty-acid--CoA ligase 6 (EC 6.2.1.3) (Long-chain acyl-CoA synthetase 6) (LACS 6).

RND1_HUMAN
θ value	4.03905 (rank : 28)	NC score	0.007514 (rank : 30)
Query Neighborhood Hits	35	Target Neighborhood Hits	230	Shared Neighborhood Hits	3
SwissProt Accessions	Q92730	Gene names	RND1, RHO6
Domain Architecture
Description	Rho-related GTP-binding protein Rho6 (Rho family GTPase 1) (Rnd1).

RND1_MOUSE
θ value	4.03905 (rank : 29)	NC score	0.007438 (rank : 31)
Query Neighborhood Hits	35	Target Neighborhood Hits	228	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BLR7, Q3TSQ9, Q80ZR7, Q8BYF2	Gene names	Rnd1, Rho6
Domain Architecture	No domain graphic available
Description	Rho-related GTP-binding protein Rho6 (Rho family GTPase 1) (Rnd1).

ACSL1_HUMAN
θ value	6.88961 (rank : 30)	NC score	0.084434 (rank : 25)
Query Neighborhood Hits	35	Target Neighborhood Hits	24	Shared Neighborhood Hits	19
SwissProt Accessions	P33121, P41215, Q8N8V7, Q8TA99	Gene names	ACSL1, FACL1, FACL2, LACS, LACS1, LACS2
Domain Architecture
Description	Long-chain-fatty-acid--CoA ligase 1 (EC 6.2.1.3) (Long-chain acyl-CoA synthetase 1) (LACS 1) (Palmitoyl-CoA ligase 1) (Long-chain fatty acid CoA ligase 2) (Long-chain acyl-CoA synthetase 2) (LACS 2) (Acyl-CoA synthetase 1) (ACS1) (Palmitoyl-CoA ligase 2).

ACSL1_MOUSE
θ value	6.88961 (rank : 31)	NC score	0.097038 (rank : 21)
Query Neighborhood Hits	35	Target Neighborhood Hits	28	Shared Neighborhood Hits	23
SwissProt Accessions	P41216, Q9DBK5	Gene names	Acsl1, Acsl2, Facl2
Domain Architecture
Description	Long-chain-fatty-acid--CoA ligase 1 (EC 6.2.1.3) (Long-chain acyl-CoA synthetase 1) (LACS 1).

C163A_HUMAN
θ value	6.88961 (rank : 32)	NC score	0.005999 (rank : 33)
Query Neighborhood Hits	35	Target Neighborhood Hits	54	Shared Neighborhood Hits	2
SwissProt Accessions	Q86VB7, Q07898, Q07899, Q07900, Q07901, Q2VLH7	Gene names	CD163, M130
Domain Architecture	No domain graphic available
Description	Scavenger receptor cysteine-rich type 1 protein M130 precursor (CD163 antigen) (Hemoglobin scavenger receptor) [Contains: Soluble CD163 (sCD163)].

MEP1A_HUMAN
θ value	6.88961 (rank : 33)	NC score	0.007809 (rank : 29)
Query Neighborhood Hits	35	Target Neighborhood Hits	162	Shared Neighborhood Hits	2
SwissProt Accessions	Q16819	Gene names	MEP1A
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit alpha) (PABA peptide hydrolase) (PPH alpha).

SDK1_MOUSE
θ value	6.88961 (rank : 34)	NC score	0.007311 (rank : 32)
Query Neighborhood Hits	35	Target Neighborhood Hits	495	Shared Neighborhood Hits	4
SwissProt Accessions	Q3UH53, Q3UFD1, Q6PAL2, Q6V3A4, Q8BMC2, Q8BZI1	Gene names	Sdk1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

SIAE_HUMAN
θ value	6.88961 (rank : 35)	NC score	0.021244 (rank : 28)
Query Neighborhood Hits	35	Target Neighborhood Hits	5	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HAT2, Q8IUT9, Q9HAU7, Q9NT71	Gene names	SIAE, YSG2
Domain Architecture	No domain graphic available
Description	Sialate O-acetylesterase precursor (EC 3.1.1.53) (Sialic acid-specific 9-O-acetylesterase) (H-Lse).

ACSL5_MOUSE
θ value	θ > 10 (rank : 36)	NC score	0.091508 (rank : 23)
Query Neighborhood Hits	35	Target Neighborhood Hits	32	Shared Neighborhood Hits	21
SwissProt Accessions	Q8JZR0	Gene names	Acsl5, Facl5
Domain Architecture
Description	Long-chain-fatty-acid--CoA ligase 5 (EC 6.2.1.3) (Long-chain acyl-CoA synthetase 5) (LACS 5).

Hits sorted by NC score

ACS2L_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	35	Target Neighborhood Hits	35	Shared Neighborhood Hits	35
SwissProt Accessions	Q99NB1, Q8K0M6	Gene names	Acss1, Acas2, Acas2l
Domain Architecture
Description	Acetyl-coenzyme A synthetase 2-like, mitochondrial precursor (EC 6.2.1.1) (Acetate--CoA ligase 2) (Acetyl-CoA synthetase 2) (AceCS2) (Acyl-CoA synthetase short-chain family member 1).

ACS2L_HUMAN
NC score	0.997742 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	35	Target Neighborhood Hits	30	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NUB1, Q5TF42, Q8IV99, Q8N234, Q96JI1, Q96JX6, Q9NU28	Gene names	ACSS1, ACAS2L, KIAA1846
Domain Architecture
Description	Acetyl-coenzyme A synthetase 2-like, mitochondrial precursor (EC 6.2.1.1) (Acetate--CoA ligase 2) (Acetyl-CoA synthetase 2) (Acyl- CoA synthetase short-chain family member 1).

ACSA_HUMAN
NC score	0.967818 (rank : 3)	θ value	2.57449e-172 (rank : 3)
Query Neighborhood Hits	35	Target Neighborhood Hits	30	Shared Neighborhood Hits	21
SwissProt Accessions	Q9NR19, Q5QPH2, Q96EL0, Q9NQP7, Q9UJ15	Gene names	ACSS2, ACAS2
Domain Architecture
Description	Acetyl-coenzyme A synthetase, cytoplasmic (EC 6.2.1.1) (Acetate--CoA ligase) (Acyl-activating enzyme) (Acetyl-CoA synthetase) (ACS) (AceCS) (Acyl-CoA synthetase short-chain family member 2).

ACSA_MOUSE
NC score	0.966652 (rank : 4)	θ value	8.57033e-168 (rank : 4)
Query Neighborhood Hits	35	Target Neighborhood Hits	27	Shared Neighborhood Hits	20
SwissProt Accessions	Q9QXG4	Gene names	Acss2, Acas2, Acecs1
Domain Architecture
Description	Acetyl-coenzyme A synthetase, cytoplasmic (EC 6.2.1.1) (Acetate--CoA ligase) (Acyl-activating enzyme) (Acetyl-CoA synthetase) (ACS) (AceCS) (Acyl-CoA synthetase short-chain family member 2).

S27A4_HUMAN
NC score	0.479681 (rank : 5)	θ value	7.09661e-13 (rank : 8)
Query Neighborhood Hits	35	Target Neighborhood Hits	28	Shared Neighborhood Hits	24
SwissProt Accessions	Q6P1M0, O95186	Gene names	SLC27A4, ACSVL4, FATP4
Domain Architecture	No domain graphic available
Description	Long-chain fatty acid transport protein 4 (EC 6.2.1.-) (Fatty acid transport protein 4) (FATP-4) (Solute carrier family 27 member 4).

S27A1_HUMAN
NC score	0.477921 (rank : 6)	θ value	2.60593e-15 (rank : 5)
Query Neighborhood Hits	35	Target Neighborhood Hits	27	Shared Neighborhood Hits	23
SwissProt Accessions	Q6PCB7	Gene names	SLC27A1, ACSVL5, FATP1
Domain Architecture	No domain graphic available
Description	Long-chain fatty acid transport protein 1 (EC 6.2.1.-) (Fatty acid transport protein 1) (FATP-1) (Solute carrier family 27 member 1).

S27A4_MOUSE
NC score	0.474101 (rank : 7)	θ value	4.16044e-13 (rank : 7)
Query Neighborhood Hits	35	Target Neighborhood Hits	29	Shared Neighborhood Hits	24
SwissProt Accessions	Q91VE0, O88562	Gene names	Slc27a4, Acsvl4, Fatp4
Domain Architecture	No domain graphic available
Description	Long-chain fatty acid transport protein 4 (EC 6.2.1.-) (Fatty acid transport protein 4) (FATP-4) (Solute carrier family 27 member 4).

S27A1_MOUSE
NC score	0.471267 (rank : 8)	θ value	2.20605e-14 (rank : 6)
Query Neighborhood Hits	35	Target Neighborhood Hits	24	Shared Neighborhood Hits	22
SwissProt Accessions	Q60714	Gene names	Slc27a1, Fatp, Fatp1
Domain Architecture
Description	Long-chain fatty acid transport protein 1 (EC 6.2.1.-) (Fatty acid transport protein 1) (FATP-1) (Solute carrier family 27 member 1).

S27A6_HUMAN
NC score	0.419415 (rank : 9)	θ value	1.47974e-10 (rank : 9)
Query Neighborhood Hits	35	Target Neighborhood Hits	26	Shared Neighborhood Hits	20
SwissProt Accessions	Q9Y2P4, Q6IAM5, Q7Z6E6, Q86YF6	Gene names	SLC27A6, ACSVL2, FACVL2, FATP1
Domain Architecture	No domain graphic available
Description	Long-chain fatty acid transport protein 6 (Fatty acid transport protein 6) (FATP-6) (Very long-chain acyl-CoA synthetase homolog 1) (VLCSH1) (hVLCS-H1) (Fatty-acid-coenzyme A ligase, very long-chain 2) (Solute carrier family 27 member 6).

S27A3_HUMAN
NC score	0.390334 (rank : 10)	θ value	7.1131e-05 (rank : 10)
Query Neighborhood Hits	35	Target Neighborhood Hits	38	Shared Neighborhood Hits	24
SwissProt Accessions	Q5K4L6, Q5VUQ7, Q5VUQ8, Q6ZV16, Q8N2X7, Q96SW5, Q9BTJ5, Q9BTY5	Gene names	SLC27A3, ACSVL3, FATP3
Domain Architecture	No domain graphic available
Description	Long-chain fatty acid transport protein 3 (EC 6.2.1.-) (Fatty acid transport protein 3) (FATP-3) (Very long-chain acyl-CoA synthetase homolog 3) (VLCS-3) (Solute carrier family 27 member 3).

S27A5_HUMAN
NC score	0.384055 (rank : 11)	θ value	0.00228821 (rank : 14)
Query Neighborhood Hits	35	Target Neighborhood Hits	28	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y2P5	Gene names	SLC27A5, ACSB, ACSVL6, FACVL3, FATP5
Domain Architecture	No domain graphic available
Description	Bile acyl-CoA synthetase (EC 6.2.1.7) (BACS) (Bile acid CoA ligase) (BA-CoA ligase) (BAL) (Cholate--CoA ligase) (Very long-chain acyl-CoA synthetase homolog 2) (VLCSH2) (VLCS-H2) (Very long chain acyl-CoA synthetase-related protein) (VLACS-related) (VLACSR) (Fatty-acid- coenzyme A ligase, very long-chain 3) (Fatty acid transport protein 5) (FATP-5) (Solute carrier family 27 member 5).

S27A5_MOUSE
NC score	0.382670 (rank : 12)	θ value	0.0563607 (rank : 16)
Query Neighborhood Hits	35	Target Neighborhood Hits	31	Shared Neighborhood Hits	24
SwissProt Accessions	Q4LDG0, O88694, Q91VD5	Gene names	Slc27a5, Acsb, Acsvl6, Fatp5, Vlacsr
Domain Architecture	No domain graphic available
Description	Bile acyl-CoA synthetase (EC 6.2.1.7) (BACS) (Bile acid CoA ligase) (BA-CoA ligase) (BAL) (Cholate--CoA ligase) (Very long chain acyl-CoA synthetase-related protein) (VLACS-related) (VLACSR) (Fatty acid transport protein 5) (FATP-5) (Solute carrier family 27 member 5).

S27A3_MOUSE
NC score	0.375553 (rank : 13)	θ value	0.0961366 (rank : 17)
Query Neighborhood Hits	35	Target Neighborhood Hits	32	Shared Neighborhood Hits	24
SwissProt Accessions	O88561, Q6PAU1, Q8BK70	Gene names	Slc27a3, Acsvl3, Fatp3
Domain Architecture	No domain graphic available
Description	Long-chain fatty acid transport protein 3 (EC 6.2.1.-) (Fatty acid transport protein 3) (FATP-3) (Solute carrier family 27 member 3).

S27A2_MOUSE
NC score	0.374517 (rank : 14)	θ value	0.000786445 (rank : 11)
Query Neighborhood Hits	35	Target Neighborhood Hits	27	Shared Neighborhood Hits	21
SwissProt Accessions	O35488, O70550, O88560	Gene names	Slc27a2, Acsvl1, Facvl1, Fatp2, Vlacs, Vlcs
Domain Architecture
Description	Very-long-chain acyl-CoA synthetase (EC 6.2.1.-) (VLCS) (Very-long- chain-fatty-acid-CoA ligase) (VLACS) (THCA-CoA ligase) (Fatty-acid- coenzyme A ligase, very long-chain 1) (Long-chain-fatty-acid--CoA ligase) (EC 6.2.1.3) (Fatty acid transport protein 2) (FATP-2) (Solute carrier family 27 member 2).

S27A2_HUMAN
NC score	0.362446 (rank : 15)	θ value	0.00102713 (rank : 12)
Query Neighborhood Hits	35	Target Neighborhood Hits	30	Shared Neighborhood Hits	24
SwissProt Accessions	O14975	Gene names	SLC27A2, ACSVL1, FACVL1, FATP2, VLACS
Domain Architecture
Description	Very-long-chain acyl-CoA synthetase (EC 6.2.1.-) (VLCS) (Very-long- chain-fatty-acid-CoA ligase) (VLACS) (THCA-CoA ligase) (Fatty-acid- coenzyme A ligase, very long-chain 1) (Long-chain-fatty-acid--CoA ligase) (EC 6.2.1.3) (Fatty acid transport protein 2) (FATP-2) (Solute carrier family 27 member 2).

ACSL4_MOUSE
NC score	0.185515 (rank : 16)	θ value	0.00134147 (rank : 13)
Query Neighborhood Hits	35	Target Neighborhood Hits	32	Shared Neighborhood Hits	23
SwissProt Accessions	Q9QUJ7, Q9JHT4, Q9R0H3	Gene names	Acsl4, Acs4, Facl4
Domain Architecture
Description	Long-chain-fatty-acid--CoA ligase 4 (EC 6.2.1.3) (Long-chain acyl-CoA synthetase 4) (LACS 4) (mACS4).

ACSL4_HUMAN
NC score	0.165807 (rank : 17)	θ value	0.163984 (rank : 19)
Query Neighborhood Hits	35	Target Neighborhood Hits	31	Shared Neighborhood Hits	22
SwissProt Accessions	O60488, O60848, O60849	Gene names	ACSL4, ACS4, FACL4, LACS4
Domain Architecture
Description	Long-chain-fatty-acid--CoA ligase 4 (EC 6.2.1.3) (Long-chain acyl-CoA synthetase 4) (LACS 4).

ACSL3_HUMAN
NC score	0.159148 (rank : 18)	θ value	0.0252991 (rank : 15)
Query Neighborhood Hits	35	Target Neighborhood Hits	25	Shared Neighborhood Hits	24
SwissProt Accessions	O95573, Q60I92, Q8IUM9	Gene names	ACSL3, ACS3, FACL3, LACS3
Domain Architecture
Description	Long-chain-fatty-acid--CoA ligase 3 (EC 6.2.1.3) (Long-chain acyl-CoA synthetase 3) (LACS 3).

ACSL3_MOUSE
NC score	0.141718 (rank : 19)	θ value	0.125558 (rank : 18)
Query Neighborhood Hits	35	Target Neighborhood Hits	26	Shared Neighborhood Hits	24
SwissProt Accessions	Q9CZW4	Gene names	Acsl3, Acs3, Facl3
Domain Architecture
Description	Long-chain-fatty-acid--CoA ligase 3 (EC 6.2.1.3) (Long-chain acyl-CoA synthetase 3) (LACS 3).

ACSL5_HUMAN
NC score	0.108248 (rank : 20)	θ value	1.38821 (rank : 20)
Query Neighborhood Hits	35	Target Neighborhood Hits	30	Shared Neighborhood Hits	21
SwissProt Accessions	Q9ULC5, Q6UX44, Q9UIU4	Gene names	ACSL5, ACS5, FACL5
Domain Architecture
Description	Long-chain-fatty-acid--CoA ligase 5 (EC 6.2.1.3) (Long-chain acyl-CoA synthetase 5) (LACS 5).

ACSL1_MOUSE
NC score	0.097038 (rank : 21)	θ value	6.88961 (rank : 31)
Query Neighborhood Hits	35	Target Neighborhood Hits	28	Shared Neighborhood Hits	23
SwissProt Accessions	P41216, Q9DBK5	Gene names	Acsl1, Acsl2, Facl2
Domain Architecture
Description	Long-chain-fatty-acid--CoA ligase 1 (EC 6.2.1.3) (Long-chain acyl-CoA synthetase 1) (LACS 1).

ACSL6_MOUSE
NC score	0.096444 (rank : 22)	θ value	1.38821 (rank : 21)
Query Neighborhood Hits	35	Target Neighborhood Hits	29	Shared Neighborhood Hits	20
SwissProt Accessions	Q91WC3, Q80ZF1	Gene names	Acsl6, Facl6
Domain Architecture
Description	Long-chain-fatty-acid--CoA ligase 6 (EC 6.2.1.3) (Long-chain acyl-CoA synthetase 6) (LACS 6).

ACSL5_MOUSE
NC score	0.091508 (rank : 23)	θ value	θ > 10 (rank : 36)
Query Neighborhood Hits	35	Target Neighborhood Hits	32	Shared Neighborhood Hits	21
SwissProt Accessions	Q8JZR0	Gene names	Acsl5, Facl5
Domain Architecture
Description	Long-chain-fatty-acid--CoA ligase 5 (EC 6.2.1.3) (Long-chain acyl-CoA synthetase 5) (LACS 5).

ACSL6_HUMAN
NC score	0.090727 (rank : 24)	θ value	4.03905 (rank : 27)
Query Neighborhood Hits	35	Target Neighborhood Hits	29	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UKU0, O94924, O95829	Gene names	ACSL6, ACS2, FACL6, KIAA0837, LACS5
Domain Architecture
Description	Long-chain-fatty-acid--CoA ligase 6 (EC 6.2.1.3) (Long-chain acyl-CoA synthetase 6) (LACS 6).

ACSL1_HUMAN
NC score	0.084434 (rank : 25)	θ value	6.88961 (rank : 30)
Query Neighborhood Hits	35	Target Neighborhood Hits	24	Shared Neighborhood Hits	19
SwissProt Accessions	P33121, P41215, Q8N8V7, Q8TA99	Gene names	ACSL1, FACL1, FACL2, LACS, LACS1, LACS2
Domain Architecture
Description	Long-chain-fatty-acid--CoA ligase 1 (EC 6.2.1.3) (Long-chain acyl-CoA synthetase 1) (LACS 1) (Palmitoyl-CoA ligase 1) (Long-chain fatty acid CoA ligase 2) (Long-chain acyl-CoA synthetase 2) (LACS 2) (Acyl-CoA synthetase 1) (ACS1) (Palmitoyl-CoA ligase 2).

PARG_MOUSE
NC score	0.035508 (rank : 26)	θ value	3.0926 (rank : 24)
Query Neighborhood Hits	35	Target Neighborhood Hits	54	Shared Neighborhood Hits	4
SwissProt Accessions	O88622, Q80YQ6, Q8CB72	Gene names	Parg
Domain Architecture	No domain graphic available
Description	Poly(ADP-ribose) glycohydrolase (EC 3.2.1.143).

PARG_HUMAN
NC score	0.034735 (rank : 27)	θ value	3.0926 (rank : 23)
Query Neighborhood Hits	35	Target Neighborhood Hits	97	Shared Neighborhood Hits	4
SwissProt Accessions	Q86W56, Q6E4P6, Q6E4P7, Q7Z742, Q9Y4W7	Gene names	PARG
Domain Architecture	No domain graphic available
Description	Poly(ADP-ribose) glycohydrolase (EC 3.2.1.143).

SIAE_HUMAN
NC score	0.021244 (rank : 28)	θ value	6.88961 (rank : 35)
Query Neighborhood Hits	35	Target Neighborhood Hits	5	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HAT2, Q8IUT9, Q9HAU7, Q9NT71	Gene names	SIAE, YSG2
Domain Architecture	No domain graphic available
Description	Sialate O-acetylesterase precursor (EC 3.1.1.53) (Sialic acid-specific 9-O-acetylesterase) (H-Lse).

MEP1A_HUMAN
NC score	0.007809 (rank : 29)	θ value	6.88961 (rank : 33)
Query Neighborhood Hits	35	Target Neighborhood Hits	162	Shared Neighborhood Hits	2
SwissProt Accessions	Q16819	Gene names	MEP1A
Domain Architecture
Description	Meprin A subunit alpha precursor (EC 3.4.24.18) (Endopeptidase-2) (N- benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit alpha) (PABA peptide hydrolase) (PPH alpha).

RND1_HUMAN
NC score	0.007514 (rank : 30)	θ value	4.03905 (rank : 28)
Query Neighborhood Hits	35	Target Neighborhood Hits	230	Shared Neighborhood Hits	3
SwissProt Accessions	Q92730	Gene names	RND1, RHO6
Domain Architecture
Description	Rho-related GTP-binding protein Rho6 (Rho family GTPase 1) (Rnd1).

RND1_MOUSE
NC score	0.007438 (rank : 31)	θ value	4.03905 (rank : 29)
Query Neighborhood Hits	35	Target Neighborhood Hits	228	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BLR7, Q3TSQ9, Q80ZR7, Q8BYF2	Gene names	Rnd1, Rho6
Domain Architecture	No domain graphic available
Description	Rho-related GTP-binding protein Rho6 (Rho family GTPase 1) (Rnd1).

SDK1_MOUSE
NC score	0.007311 (rank : 32)	θ value	6.88961 (rank : 34)
Query Neighborhood Hits	35	Target Neighborhood Hits	495	Shared Neighborhood Hits	4
SwissProt Accessions	Q3UH53, Q3UFD1, Q6PAL2, Q6V3A4, Q8BMC2, Q8BZI1	Gene names	Sdk1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

C163A_HUMAN
NC score	0.005999 (rank : 33)	θ value	6.88961 (rank : 32)
Query Neighborhood Hits	35	Target Neighborhood Hits	54	Shared Neighborhood Hits	2
SwissProt Accessions	Q86VB7, Q07898, Q07899, Q07900, Q07901, Q2VLH7	Gene names	CD163, M130
Domain Architecture	No domain graphic available
Description	Scavenger receptor cysteine-rich type 1 protein M130 precursor (CD163 antigen) (Hemoglobin scavenger receptor) [Contains: Soluble CD163 (sCD163)].

SDK1_HUMAN
NC score	0.005939 (rank : 34)	θ value	3.0926 (rank : 25)
Query Neighborhood Hits	35	Target Neighborhood Hits	511	Shared Neighborhood Hits	3
SwissProt Accessions	Q7Z5N4, Q8TEN9, Q8TEP5, Q96N44	Gene names	SDK1
Domain Architecture	No domain graphic available
Description	Protein sidekick-1 precursor.

SYNE2_HUMAN
NC score	0.004955 (rank : 35)	θ value	3.0926 (rank : 26)
Query Neighborhood Hits	35	Target Neighborhood Hits	1323	Shared Neighborhood Hits	2
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

KS6A5_MOUSE
NC score	0.002598 (rank : 36)	θ value	1.81305 (rank : 22)
Query Neighborhood Hits	35	Target Neighborhood Hits	854	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C050, Q8CI92	Gene names	Rps6ka5, Msk1
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1) (Nuclear mitogen- and stress-activated protein kinase 1) (90 kDa ribosomal protein S6 kinase 5) (RSK-like protein kinase) (RLSK).