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Network neighborhood for query Sequence : HYAL2_HUMAN

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HYAL2_HUMAN
SwissProt Accessions	Q12891, O15177, Q9BW29	Gene names	HYAL2, LUCA2
Domain Architecture
Description	Hyaluronidase-2 precursor (EC 3.2.1.35) (Hyal-2) (Hyaluronoglucosaminidase-2) (LUCA-2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

HYAL2_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	24	Target Neighborhood Hits	24	Shared Neighborhood Hits	24
SwissProt Accessions	Q12891, O15177, Q9BW29	Gene names	HYAL2, LUCA2
Domain Architecture
Description	Hyaluronidase-2 precursor (EC 3.2.1.35) (Hyal-2) (Hyaluronoglucosaminidase-2) (LUCA-2).

HYAL2_MOUSE
θ value	0 (rank : 2)	NC score	0.997381 (rank : 2)
Query Neighborhood Hits	24	Target Neighborhood Hits	16	Shared Neighborhood Hits	10
SwissProt Accessions	O35632, O35631, Q99MS9, Q99MT0	Gene names	Hyal2
Domain Architecture
Description	Hyaluronidase-2 precursor (EC 3.2.1.35) (Hyal-2) (Hyaluronoglucosaminidase-2) (LUCA-2).

HYALP_HUMAN
θ value	7.17548e-90 (rank : 3)	NC score	0.967943 (rank : 4)
Query Neighborhood Hits	24	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	P38567	Gene names	SPAM1, HYAL3, PH20
Domain Architecture
Description	Hyaluronidase PH-20 precursor (EC 3.2.1.35) (Hyal-PH20) (Sperm surface protein PH-20) (Sperm adhesion molecule 1).

HYAL1_HUMAN
θ value	3.0147e-88 (rank : 4)	NC score	0.968939 (rank : 3)
Query Neighborhood Hits	24	Target Neighborhood Hits	19	Shared Neighborhood Hits	13
SwissProt Accessions	Q12794, Q6FH23, Q6PIZ6, Q7KYU2, Q7LE34, Q8NFK5, Q8NFK6, Q8NFK7, Q8NFK8, Q8NFK9, Q93013, Q9UKD5, Q9UNI8	Gene names	HYAL1, LUCA1
Domain Architecture	No domain graphic available
Description	Hyaluronidase-1 precursor (EC 3.2.1.35) (Hyal-1) (Hyaluronoglucosaminidase-1) (LUCA-1).

HYALP_MOUSE
θ value	3.93732e-88 (rank : 5)	NC score	0.965819 (rank : 6)
Query Neighborhood Hits	24	Target Neighborhood Hits	12	Shared Neighborhood Hits	8
SwissProt Accessions	P48794, Q7TSD6, Q812F4, Q9DAQ1	Gene names	Spam1, Ph20, Spam
Domain Architecture
Description	Hyaluronidase PH-20 precursor (EC 3.2.1.35) (Hyal-PH20) (Sperm surface protein PH-20) (Sperm adhesion molecule 1).

HYAL1_MOUSE
θ value	1.07224e-85 (rank : 6)	NC score	0.966870 (rank : 5)
Query Neighborhood Hits	24	Target Neighborhood Hits	17	Shared Neighborhood Hits	10
SwissProt Accessions	Q91ZJ9, O70229, Q8CE62, Q8QZX3, Q8VBW7, Q8VDK0	Gene names	Hyal1
Domain Architecture	No domain graphic available
Description	Hyaluronidase-1 precursor (EC 3.2.1.35) (Hyal-1) (Hyaluronoglucosaminidase-1).

HYAL3_HUMAN
θ value	3.22841e-82 (rank : 7)	NC score	0.957724 (rank : 7)
Query Neighborhood Hits	24	Target Neighborhood Hits	45	Shared Neighborhood Hits	14
SwissProt Accessions	O43820, O60540, Q8NFK2, Q8NFK3, Q8NFK4, Q96E56, Q9BRW9	Gene names	HYAL3, LUCA3
Domain Architecture	No domain graphic available
Description	Hyaluronidase-3 precursor (EC 3.2.1.35) (Hyal-3) (Hyaluronoglucosaminidase-3) (LUCA-3).

HYAL3_MOUSE
θ value	3.12697e-77 (rank : 8)	NC score	0.951003 (rank : 8)
Query Neighborhood Hits	24	Target Neighborhood Hits	44	Shared Neighborhood Hits	15
SwissProt Accessions	Q8VEI3, Q8VBX7, Q8VI77	Gene names	Hyal3, Hyl3
Domain Architecture	No domain graphic available
Description	Hyaluronidase-3 precursor (EC 3.2.1.35) (Hyal-3) (Hyaluronoglucosaminidase-3).

DNER_HUMAN
θ value	0.0736092 (rank : 9)	NC score	0.032136 (rank : 9)
Query Neighborhood Hits	24	Target Neighborhood Hits	460	Shared Neighborhood Hits	16
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

DNER_MOUSE
θ value	0.47712 (rank : 10)	NC score	0.030501 (rank : 10)
Query Neighborhood Hits	24	Target Neighborhood Hits	413	Shared Neighborhood Hits	16
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

NOTC4_HUMAN
θ value	0.62314 (rank : 11)	NC score	0.023880 (rank : 14)
Query Neighborhood Hits	24	Target Neighborhood Hits	905	Shared Neighborhood Hits	19
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

CRUM1_HUMAN
θ value	1.81305 (rank : 12)	NC score	0.028881 (rank : 11)
Query Neighborhood Hits	24	Target Neighborhood Hits	457	Shared Neighborhood Hits	20
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

NOTC2_MOUSE
θ value	2.36792 (rank : 13)	NC score	0.021056 (rank : 17)
Query Neighborhood Hits	24	Target Neighborhood Hits	1069	Shared Neighborhood Hits	16
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

ZN409_HUMAN
θ value	2.36792 (rank : 14)	NC score	0.009147 (rank : 24)
Query Neighborhood Hits	24	Target Neighborhood Hits	842	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UPU6	Gene names	ZNF409, KIAA1056
Domain Architecture	No domain graphic available
Description	Zinc finger protein 409.

ITB8_HUMAN
θ value	3.0926 (rank : 15)	NC score	0.019064 (rank : 21)
Query Neighborhood Hits	24	Target Neighborhood Hits	280	Shared Neighborhood Hits	17
SwissProt Accessions	P26012	Gene names	ITGB8
Domain Architecture
Description	Integrin beta-8 precursor.

NOTC2_HUMAN
θ value	5.27518 (rank : 16)	NC score	0.020340 (rank : 19)
Query Neighborhood Hits	24	Target Neighborhood Hits	1113	Shared Neighborhood Hits	16
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

PROS_HUMAN
θ value	5.27518 (rank : 17)	NC score	0.017102 (rank : 23)
Query Neighborhood Hits	24	Target Neighborhood Hits	340	Shared Neighborhood Hits	15
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

NOTC1_MOUSE
θ value	6.88961 (rank : 18)	NC score	0.023933 (rank : 13)
Query Neighborhood Hits	24	Target Neighborhood Hits	916	Shared Neighborhood Hits	19
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

PROS_MOUSE
θ value	6.88961 (rank : 19)	NC score	0.017155 (rank : 22)
Query Neighborhood Hits	24	Target Neighborhood Hits	330	Shared Neighborhood Hits	16
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

STAB1_HUMAN
θ value	6.88961 (rank : 20)	NC score	0.019462 (rank : 20)
Query Neighborhood Hits	24	Target Neighborhood Hits	546	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

CRUM2_HUMAN
θ value	8.99809 (rank : 21)	NC score	0.027142 (rank : 12)
Query Neighborhood Hits	24	Target Neighborhood Hits	453	Shared Neighborhood Hits	18
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

NOTC1_HUMAN
θ value	8.99809 (rank : 22)	NC score	0.020362 (rank : 18)
Query Neighborhood Hits	24	Target Neighborhood Hits	906	Shared Neighborhood Hits	17
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC3_HUMAN
θ value	8.99809 (rank : 23)	NC score	0.021411 (rank : 16)
Query Neighborhood Hits	24	Target Neighborhood Hits	1062	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC3_MOUSE
θ value	8.99809 (rank : 24)	NC score	0.022426 (rank : 15)
Query Neighborhood Hits	24	Target Neighborhood Hits	975	Shared Neighborhood Hits	19
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

Hits sorted by NC score

HYAL2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	24	Target Neighborhood Hits	24	Shared Neighborhood Hits	24
SwissProt Accessions	Q12891, O15177, Q9BW29	Gene names	HYAL2, LUCA2
Domain Architecture
Description	Hyaluronidase-2 precursor (EC 3.2.1.35) (Hyal-2) (Hyaluronoglucosaminidase-2) (LUCA-2).

HYAL2_MOUSE
NC score	0.997381 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	24	Target Neighborhood Hits	16	Shared Neighborhood Hits	10
SwissProt Accessions	O35632, O35631, Q99MS9, Q99MT0	Gene names	Hyal2
Domain Architecture
Description	Hyaluronidase-2 precursor (EC 3.2.1.35) (Hyal-2) (Hyaluronoglucosaminidase-2) (LUCA-2).

HYAL1_HUMAN
NC score	0.968939 (rank : 3)	θ value	3.0147e-88 (rank : 4)
Query Neighborhood Hits	24	Target Neighborhood Hits	19	Shared Neighborhood Hits	13
SwissProt Accessions	Q12794, Q6FH23, Q6PIZ6, Q7KYU2, Q7LE34, Q8NFK5, Q8NFK6, Q8NFK7, Q8NFK8, Q8NFK9, Q93013, Q9UKD5, Q9UNI8	Gene names	HYAL1, LUCA1
Domain Architecture	No domain graphic available
Description	Hyaluronidase-1 precursor (EC 3.2.1.35) (Hyal-1) (Hyaluronoglucosaminidase-1) (LUCA-1).

HYALP_HUMAN
NC score	0.967943 (rank : 4)	θ value	7.17548e-90 (rank : 3)
Query Neighborhood Hits	24	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	P38567	Gene names	SPAM1, HYAL3, PH20
Domain Architecture
Description	Hyaluronidase PH-20 precursor (EC 3.2.1.35) (Hyal-PH20) (Sperm surface protein PH-20) (Sperm adhesion molecule 1).

HYAL1_MOUSE
NC score	0.966870 (rank : 5)	θ value	1.07224e-85 (rank : 6)
Query Neighborhood Hits	24	Target Neighborhood Hits	17	Shared Neighborhood Hits	10
SwissProt Accessions	Q91ZJ9, O70229, Q8CE62, Q8QZX3, Q8VBW7, Q8VDK0	Gene names	Hyal1
Domain Architecture	No domain graphic available
Description	Hyaluronidase-1 precursor (EC 3.2.1.35) (Hyal-1) (Hyaluronoglucosaminidase-1).

HYALP_MOUSE
NC score	0.965819 (rank : 6)	θ value	3.93732e-88 (rank : 5)
Query Neighborhood Hits	24	Target Neighborhood Hits	12	Shared Neighborhood Hits	8
SwissProt Accessions	P48794, Q7TSD6, Q812F4, Q9DAQ1	Gene names	Spam1, Ph20, Spam
Domain Architecture
Description	Hyaluronidase PH-20 precursor (EC 3.2.1.35) (Hyal-PH20) (Sperm surface protein PH-20) (Sperm adhesion molecule 1).

HYAL3_HUMAN
NC score	0.957724 (rank : 7)	θ value	3.22841e-82 (rank : 7)
Query Neighborhood Hits	24	Target Neighborhood Hits	45	Shared Neighborhood Hits	14
SwissProt Accessions	O43820, O60540, Q8NFK2, Q8NFK3, Q8NFK4, Q96E56, Q9BRW9	Gene names	HYAL3, LUCA3
Domain Architecture	No domain graphic available
Description	Hyaluronidase-3 precursor (EC 3.2.1.35) (Hyal-3) (Hyaluronoglucosaminidase-3) (LUCA-3).

HYAL3_MOUSE
NC score	0.951003 (rank : 8)	θ value	3.12697e-77 (rank : 8)
Query Neighborhood Hits	24	Target Neighborhood Hits	44	Shared Neighborhood Hits	15
SwissProt Accessions	Q8VEI3, Q8VBX7, Q8VI77	Gene names	Hyal3, Hyl3
Domain Architecture	No domain graphic available
Description	Hyaluronidase-3 precursor (EC 3.2.1.35) (Hyal-3) (Hyaluronoglucosaminidase-3).

DNER_HUMAN
NC score	0.032136 (rank : 9)	θ value	0.0736092 (rank : 9)
Query Neighborhood Hits	24	Target Neighborhood Hits	460	Shared Neighborhood Hits	16
SwissProt Accessions	Q8NFT8, Q53R88, Q53TP7, Q53TQ5, Q8IYT0, Q8TB42, Q9NTF1, Q9UDM2	Gene names	DNER, BET
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor.

DNER_MOUSE
NC score	0.030501 (rank : 10)	θ value	0.47712 (rank : 10)
Query Neighborhood Hits	24	Target Neighborhood Hits	413	Shared Neighborhood Hits	16
SwissProt Accessions	Q8JZM4, Q3U697, Q8R226, Q8R4T6, Q8VD97	Gene names	Dner, Bet, Bret
Domain Architecture	No domain graphic available
Description	Delta and Notch-like epidermal growth factor-related receptor precursor (Brain EGF repeat-containing transmembrane protein).

CRUM1_HUMAN
NC score	0.028881 (rank : 11)	θ value	1.81305 (rank : 12)
Query Neighborhood Hits	24	Target Neighborhood Hits	457	Shared Neighborhood Hits	20
SwissProt Accessions	P82279, Q5K3A6, Q5TC28, Q5VUT1, Q6N027, Q8WWY0	Gene names	CRB1
Domain Architecture
Description	Crumbs homolog 1 precursor.

CRUM2_HUMAN
NC score	0.027142 (rank : 12)	θ value	8.99809 (rank : 21)
Query Neighborhood Hits	24	Target Neighborhood Hits	453	Shared Neighborhood Hits	18
SwissProt Accessions	Q5IJ48, Q5JS41, Q5JS43, Q6ZTA9, Q6ZWI6	Gene names	CRB2
Domain Architecture	No domain graphic available
Description	Crumbs homolog 2 precursor (Crumbs-like protein 2).

NOTC1_MOUSE
NC score	0.023933 (rank : 13)	θ value	6.88961 (rank : 18)
Query Neighborhood Hits	24	Target Neighborhood Hits	916	Shared Neighborhood Hits	19
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC4_HUMAN
NC score	0.023880 (rank : 14)	θ value	0.62314 (rank : 11)
Query Neighborhood Hits	24	Target Neighborhood Hits	905	Shared Neighborhood Hits	19
SwissProt Accessions	Q99466, O00306, Q99458, Q99940, Q9H3S8, Q9UII9, Q9UIJ0	Gene names	NOTCH4
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) (hNotch4) [Contains: Notch 4 extracellular truncation; Notch 4 intracellular domain].

NOTC3_MOUSE
NC score	0.022426 (rank : 15)	θ value	8.99809 (rank : 24)
Query Neighborhood Hits	24	Target Neighborhood Hits	975	Shared Neighborhood Hits	19
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC3_HUMAN
NC score	0.021411 (rank : 16)	θ value	8.99809 (rank : 23)
Query Neighborhood Hits	24	Target Neighborhood Hits	1062	Shared Neighborhood Hits	18
SwissProt Accessions	Q9UM47, Q9UEB3, Q9UPL3, Q9Y6L8	Gene names	NOTCH3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

NOTC2_MOUSE
NC score	0.021056 (rank : 17)	θ value	2.36792 (rank : 13)
Query Neighborhood Hits	24	Target Neighborhood Hits	1069	Shared Neighborhood Hits	16
SwissProt Accessions	O35516, Q06008, Q60941	Gene names	Notch2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (Motch B) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

NOTC1_HUMAN
NC score	0.020362 (rank : 18)	θ value	8.99809 (rank : 22)
Query Neighborhood Hits	24	Target Neighborhood Hits	906	Shared Neighborhood Hits	17
SwissProt Accessions	P46531	Gene names	NOTCH1, TAN1
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC2_HUMAN
NC score	0.020340 (rank : 19)	θ value	5.27518 (rank : 16)
Query Neighborhood Hits	24	Target Neighborhood Hits	1113	Shared Neighborhood Hits	16
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

STAB1_HUMAN
NC score	0.019462 (rank : 20)	θ value	6.88961 (rank : 20)
Query Neighborhood Hits	24	Target Neighborhood Hits	546	Shared Neighborhood Hits	18
SwissProt Accessions	Q9NY15, Q8IUH0, Q8IUH1, Q93072	Gene names	STAB1, FEEL1, KIAA0246
Domain Architecture
Description	Stabilin-1 precursor (FEEL-1 protein) (MS-1 antigen).

ITB8_HUMAN
NC score	0.019064 (rank : 21)	θ value	3.0926 (rank : 15)
Query Neighborhood Hits	24	Target Neighborhood Hits	280	Shared Neighborhood Hits	17
SwissProt Accessions	P26012	Gene names	ITGB8
Domain Architecture
Description	Integrin beta-8 precursor.

PROS_MOUSE
NC score	0.017155 (rank : 22)	θ value	6.88961 (rank : 19)
Query Neighborhood Hits	24	Target Neighborhood Hits	330	Shared Neighborhood Hits	16
SwissProt Accessions	Q08761, P43483	Gene names	Pros1, Pros
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

PROS_HUMAN
NC score	0.017102 (rank : 23)	θ value	5.27518 (rank : 17)
Query Neighborhood Hits	24	Target Neighborhood Hits	340	Shared Neighborhood Hits	15
SwissProt Accessions	P07225, Q15518, Q7Z715	Gene names	PROS1, PROS
Domain Architecture
Description	Vitamin K-dependent protein S precursor.

ZN409_HUMAN
NC score	0.009147 (rank : 24)	θ value	2.36792 (rank : 14)
Query Neighborhood Hits	24	Target Neighborhood Hits	842	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UPU6	Gene names	ZNF409, KIAA1056
Domain Architecture	No domain graphic available
Description	Zinc finger protein 409.