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Network neighborhood for query Sequence : HYAL2_MOUSE

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HYAL2_MOUSE
SwissProt Accessions	O35632, O35631, Q99MS9, Q99MT0	Gene names	Hyal2
Domain Architecture
Description	Hyaluronidase-2 precursor (EC 3.2.1.35) (Hyal-2) (Hyaluronoglucosaminidase-2) (LUCA-2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

HYAL2_HUMAN
θ value	0 (rank : 1)	NC score	0.997381 (rank : 2)
Query Neighborhood Hits	16	Target Neighborhood Hits	24	Shared Neighborhood Hits	10
SwissProt Accessions	Q12891, O15177, Q9BW29	Gene names	HYAL2, LUCA2
Domain Architecture
Description	Hyaluronidase-2 precursor (EC 3.2.1.35) (Hyal-2) (Hyaluronoglucosaminidase-2) (LUCA-2).

HYAL2_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	16	Target Neighborhood Hits	16	Shared Neighborhood Hits	16
SwissProt Accessions	O35632, O35631, Q99MS9, Q99MT0	Gene names	Hyal2
Domain Architecture
Description	Hyaluronidase-2 precursor (EC 3.2.1.35) (Hyal-2) (Hyaluronoglucosaminidase-2) (LUCA-2).

HYAL1_HUMAN
θ value	1.14293e-95 (rank : 3)	NC score	0.970764 (rank : 3)
Query Neighborhood Hits	16	Target Neighborhood Hits	19	Shared Neighborhood Hits	9
SwissProt Accessions	Q12794, Q6FH23, Q6PIZ6, Q7KYU2, Q7LE34, Q8NFK5, Q8NFK6, Q8NFK7, Q8NFK8, Q8NFK9, Q93013, Q9UKD5, Q9UNI8	Gene names	HYAL1, LUCA1
Domain Architecture	No domain graphic available
Description	Hyaluronidase-1 precursor (EC 3.2.1.35) (Hyal-1) (Hyaluronoglucosaminidase-1) (LUCA-1).

HYALP_HUMAN
θ value	8.47616e-91 (rank : 4)	NC score	0.968733 (rank : 4)
Query Neighborhood Hits	16	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	P38567	Gene names	SPAM1, HYAL3, PH20
Domain Architecture
Description	Hyaluronidase PH-20 precursor (EC 3.2.1.35) (Hyal-PH20) (Sperm surface protein PH-20) (Sperm adhesion molecule 1).

HYALP_MOUSE
θ value	8.47616e-91 (rank : 5)	NC score	0.966801 (rank : 6)
Query Neighborhood Hits	16	Target Neighborhood Hits	12	Shared Neighborhood Hits	8
SwissProt Accessions	P48794, Q7TSD6, Q812F4, Q9DAQ1	Gene names	Spam1, Ph20, Spam
Domain Architecture
Description	Hyaluronidase PH-20 precursor (EC 3.2.1.35) (Hyal-PH20) (Sperm surface protein PH-20) (Sperm adhesion molecule 1).

HYAL1_MOUSE
θ value	1.10702e-90 (rank : 6)	NC score	0.968692 (rank : 5)
Query Neighborhood Hits	16	Target Neighborhood Hits	17	Shared Neighborhood Hits	8
SwissProt Accessions	Q91ZJ9, O70229, Q8CE62, Q8QZX3, Q8VBW7, Q8VDK0	Gene names	Hyal1
Domain Architecture	No domain graphic available
Description	Hyaluronidase-1 precursor (EC 3.2.1.35) (Hyal-1) (Hyaluronoglucosaminidase-1).

HYAL3_HUMAN
θ value	1.07224e-85 (rank : 7)	NC score	0.957672 (rank : 7)
Query Neighborhood Hits	16	Target Neighborhood Hits	45	Shared Neighborhood Hits	11
SwissProt Accessions	O43820, O60540, Q8NFK2, Q8NFK3, Q8NFK4, Q96E56, Q9BRW9	Gene names	HYAL3, LUCA3
Domain Architecture	No domain graphic available
Description	Hyaluronidase-3 precursor (EC 3.2.1.35) (Hyal-3) (Hyaluronoglucosaminidase-3) (LUCA-3).

HYAL3_MOUSE
θ value	1.45253e-74 (rank : 8)	NC score	0.949996 (rank : 8)
Query Neighborhood Hits	16	Target Neighborhood Hits	44	Shared Neighborhood Hits	11
SwissProt Accessions	Q8VEI3, Q8VBX7, Q8VI77	Gene names	Hyal3, Hyl3
Domain Architecture	No domain graphic available
Description	Hyaluronidase-3 precursor (EC 3.2.1.35) (Hyal-3) (Hyaluronoglucosaminidase-3).

PON1_HUMAN
θ value	3.0926 (rank : 9)	NC score	0.012852 (rank : 11)
Query Neighborhood Hits	16	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	P27169, Q16052	Gene names	PON1, PON
Domain Architecture
Description	Serum paraoxonase/arylesterase 1 (EC 3.1.1.2) (EC 3.1.8.1) (PON 1) (Serum aryldialkylphosphatase 1) (A-esterase 1) (Aromatic esterase 1) (K-45).

ITB8_HUMAN
θ value	5.27518 (rank : 10)	NC score	0.013022 (rank : 10)
Query Neighborhood Hits	16	Target Neighborhood Hits	280	Shared Neighborhood Hits	9
SwissProt Accessions	P26012	Gene names	ITGB8
Domain Architecture
Description	Integrin beta-8 precursor.

METH_HUMAN
θ value	5.27518 (rank : 11)	NC score	0.018399 (rank : 9)
Query Neighborhood Hits	16	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q99707, Q99713, Q99723	Gene names	MTR
Domain Architecture
Description	Methionine synthase (EC 2.1.1.13) (5-methyltetrahydrofolate-- homocysteine methyltransferase) (Methionine synthase, vitamin-B12 dependent) (MS).

NOTC1_MOUSE
θ value	5.27518 (rank : 12)	NC score	0.007218 (rank : 13)
Query Neighborhood Hits	16	Target Neighborhood Hits	916	Shared Neighborhood Hits	10
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC4_MOUSE
θ value	5.27518 (rank : 13)	NC score	0.006300 (rank : 14)
Query Neighborhood Hits	16	Target Neighborhood Hits	872	Shared Neighborhood Hits	9
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

WIF1_HUMAN
θ value	5.27518 (rank : 14)	NC score	0.007389 (rank : 12)
Query Neighborhood Hits	16	Target Neighborhood Hits	392	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

CELR2_MOUSE
θ value	6.88961 (rank : 15)	NC score	0.003767 (rank : 15)
Query Neighborhood Hits	16	Target Neighborhood Hits	584	Shared Neighborhood Hits	9
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

LAMA2_MOUSE
θ value	8.99809 (rank : 16)	NC score	0.002541 (rank : 16)
Query Neighborhood Hits	16	Target Neighborhood Hits	1198	Shared Neighborhood Hits	7
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

Hits sorted by NC score

HYAL2_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	16	Target Neighborhood Hits	16	Shared Neighborhood Hits	16
SwissProt Accessions	O35632, O35631, Q99MS9, Q99MT0	Gene names	Hyal2
Domain Architecture
Description	Hyaluronidase-2 precursor (EC 3.2.1.35) (Hyal-2) (Hyaluronoglucosaminidase-2) (LUCA-2).

HYAL2_HUMAN
NC score	0.997381 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	16	Target Neighborhood Hits	24	Shared Neighborhood Hits	10
SwissProt Accessions	Q12891, O15177, Q9BW29	Gene names	HYAL2, LUCA2
Domain Architecture
Description	Hyaluronidase-2 precursor (EC 3.2.1.35) (Hyal-2) (Hyaluronoglucosaminidase-2) (LUCA-2).

HYAL1_HUMAN
NC score	0.970764 (rank : 3)	θ value	1.14293e-95 (rank : 3)
Query Neighborhood Hits	16	Target Neighborhood Hits	19	Shared Neighborhood Hits	9
SwissProt Accessions	Q12794, Q6FH23, Q6PIZ6, Q7KYU2, Q7LE34, Q8NFK5, Q8NFK6, Q8NFK7, Q8NFK8, Q8NFK9, Q93013, Q9UKD5, Q9UNI8	Gene names	HYAL1, LUCA1
Domain Architecture	No domain graphic available
Description	Hyaluronidase-1 precursor (EC 3.2.1.35) (Hyal-1) (Hyaluronoglucosaminidase-1) (LUCA-1).

HYALP_HUMAN
NC score	0.968733 (rank : 4)	θ value	8.47616e-91 (rank : 4)
Query Neighborhood Hits	16	Target Neighborhood Hits	9	Shared Neighborhood Hits	8
SwissProt Accessions	P38567	Gene names	SPAM1, HYAL3, PH20
Domain Architecture
Description	Hyaluronidase PH-20 precursor (EC 3.2.1.35) (Hyal-PH20) (Sperm surface protein PH-20) (Sperm adhesion molecule 1).

HYAL1_MOUSE
NC score	0.968692 (rank : 5)	θ value	1.10702e-90 (rank : 6)
Query Neighborhood Hits	16	Target Neighborhood Hits	17	Shared Neighborhood Hits	8
SwissProt Accessions	Q91ZJ9, O70229, Q8CE62, Q8QZX3, Q8VBW7, Q8VDK0	Gene names	Hyal1
Domain Architecture	No domain graphic available
Description	Hyaluronidase-1 precursor (EC 3.2.1.35) (Hyal-1) (Hyaluronoglucosaminidase-1).

HYALP_MOUSE
NC score	0.966801 (rank : 6)	θ value	8.47616e-91 (rank : 5)
Query Neighborhood Hits	16	Target Neighborhood Hits	12	Shared Neighborhood Hits	8
SwissProt Accessions	P48794, Q7TSD6, Q812F4, Q9DAQ1	Gene names	Spam1, Ph20, Spam
Domain Architecture
Description	Hyaluronidase PH-20 precursor (EC 3.2.1.35) (Hyal-PH20) (Sperm surface protein PH-20) (Sperm adhesion molecule 1).

HYAL3_HUMAN
NC score	0.957672 (rank : 7)	θ value	1.07224e-85 (rank : 7)
Query Neighborhood Hits	16	Target Neighborhood Hits	45	Shared Neighborhood Hits	11
SwissProt Accessions	O43820, O60540, Q8NFK2, Q8NFK3, Q8NFK4, Q96E56, Q9BRW9	Gene names	HYAL3, LUCA3
Domain Architecture	No domain graphic available
Description	Hyaluronidase-3 precursor (EC 3.2.1.35) (Hyal-3) (Hyaluronoglucosaminidase-3) (LUCA-3).

HYAL3_MOUSE
NC score	0.949996 (rank : 8)	θ value	1.45253e-74 (rank : 8)
Query Neighborhood Hits	16	Target Neighborhood Hits	44	Shared Neighborhood Hits	11
SwissProt Accessions	Q8VEI3, Q8VBX7, Q8VI77	Gene names	Hyal3, Hyl3
Domain Architecture	No domain graphic available
Description	Hyaluronidase-3 precursor (EC 3.2.1.35) (Hyal-3) (Hyaluronoglucosaminidase-3).

METH_HUMAN
NC score	0.018399 (rank : 9)	θ value	5.27518 (rank : 11)
Query Neighborhood Hits	16	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q99707, Q99713, Q99723	Gene names	MTR
Domain Architecture
Description	Methionine synthase (EC 2.1.1.13) (5-methyltetrahydrofolate-- homocysteine methyltransferase) (Methionine synthase, vitamin-B12 dependent) (MS).

ITB8_HUMAN
NC score	0.013022 (rank : 10)	θ value	5.27518 (rank : 10)
Query Neighborhood Hits	16	Target Neighborhood Hits	280	Shared Neighborhood Hits	9
SwissProt Accessions	P26012	Gene names	ITGB8
Domain Architecture
Description	Integrin beta-8 precursor.

PON1_HUMAN
NC score	0.012852 (rank : 11)	θ value	3.0926 (rank : 9)
Query Neighborhood Hits	16	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	P27169, Q16052	Gene names	PON1, PON
Domain Architecture
Description	Serum paraoxonase/arylesterase 1 (EC 3.1.1.2) (EC 3.1.8.1) (PON 1) (Serum aryldialkylphosphatase 1) (A-esterase 1) (Aromatic esterase 1) (K-45).

WIF1_HUMAN
NC score	0.007389 (rank : 12)	θ value	5.27518 (rank : 14)
Query Neighborhood Hits	16	Target Neighborhood Hits	392	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y5W5, Q6UXI1, Q8WVG4	Gene names	WIF1
Domain Architecture
Description	Wnt inhibitory factor 1 precursor (WIF-1).

NOTC1_MOUSE
NC score	0.007218 (rank : 13)	θ value	5.27518 (rank : 12)
Query Neighborhood Hits	16	Target Neighborhood Hits	916	Shared Neighborhood Hits	10
SwissProt Accessions	Q01705, Q06007, Q61905, Q99JC2, Q9QW58, Q9R0X7	Gene names	Notch1, Motch
Domain Architecture
Description	Neurogenic locus notch homolog protein 1 precursor (Notch 1) (Motch A) (mT14) (p300) [Contains: Notch 1 extracellular truncation; Notch 1 intracellular domain].

NOTC4_MOUSE
NC score	0.006300 (rank : 14)	θ value	5.27518 (rank : 13)
Query Neighborhood Hits	16	Target Neighborhood Hits	872	Shared Neighborhood Hits	9
SwissProt Accessions	P31695, O35442, O88314, O88316, Q62389, Q62390, Q9R1W9, Q9R1X0	Gene names	Notch4, Int-3, Int3
Domain Architecture
Description	Neurogenic locus notch homolog protein 4 precursor (Notch 4) [Contains: Transforming protein Int-3; Notch 4 extracellular truncation; Notch 4 intracellular domain].

CELR2_MOUSE
NC score	0.003767 (rank : 15)	θ value	6.88961 (rank : 15)
Query Neighborhood Hits	16	Target Neighborhood Hits	584	Shared Neighborhood Hits	9
SwissProt Accessions	Q9R0M0, Q99K26, Q9Z2R4	Gene names	Celsr2
Domain Architecture
Description	Cadherin EGF LAG seven-pass G-type receptor 2 precursor (Flamingo 1) (mFmi1).

LAMA2_MOUSE
NC score	0.002541 (rank : 16)	θ value	8.99809 (rank : 16)
Query Neighborhood Hits	16	Target Neighborhood Hits	1198	Shared Neighborhood Hits	7
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).