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Network neighborhood for query Sequence : PARP2_HUMAN

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PARP2_HUMAN
SwissProt Accessions	Q9UGN5, Q8TEU4, Q9NUV2, Q9UMR4, Q9Y6C8	Gene names	PARP2, ADPRT2, ADPRTL2
Domain Architecture
Description	Poly [ADP-ribose] polymerase 2 (EC 2.4.2.30) (PARP-2) (NAD(+) ADP- ribosyltransferase 2) (Poly[ADP-ribose] synthetase 2) (pADPRT-2) (hPARP-2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PARP2_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	33	Target Neighborhood Hits	33	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UGN5, Q8TEU4, Q9NUV2, Q9UMR4, Q9Y6C8	Gene names	PARP2, ADPRT2, ADPRTL2
Domain Architecture
Description	Poly [ADP-ribose] polymerase 2 (EC 2.4.2.30) (PARP-2) (NAD(+) ADP- ribosyltransferase 2) (Poly[ADP-ribose] synthetase 2) (pADPRT-2) (hPARP-2).

PARP2_MOUSE
θ value	0 (rank : 2)	NC score	0.991472 (rank : 2)
Query Neighborhood Hits	33	Target Neighborhood Hits	53	Shared Neighborhood Hits	18
SwissProt Accessions	O88554, Q99N29	Gene names	Parp2, Adprt2, Adprtl2, Aspartl2
Domain Architecture
Description	Poly [ADP-ribose] polymerase 2 (EC 2.4.2.30) (PARP-2) (NAD(+) ADP- ribosyltransferase 2) (Poly[ADP-ribose] synthetase 2) (pADPRT-2) (mPARP-2).

PARP1_HUMAN
θ value	8.73085e-104 (rank : 3)	NC score	0.920451 (rank : 4)
Query Neighborhood Hits	33	Target Neighborhood Hits	54	Shared Neighborhood Hits	14
SwissProt Accessions	P09874, Q8IUZ9	Gene names	PARP1, ADPRT, PPOL
Domain Architecture
Description	Poly [ADP-ribose] polymerase 1 (EC 2.4.2.30) (PARP-1) (ADPRT) (NAD(+) ADP-ribosyltransferase 1) (Poly[ADP-ribose] synthetase 1).

PARP1_MOUSE
θ value	2.80862e-102 (rank : 4)	NC score	0.910424 (rank : 5)
Query Neighborhood Hits	33	Target Neighborhood Hits	102	Shared Neighborhood Hits	15
SwissProt Accessions	P11103, Q9JLX4, Q9QVQ3	Gene names	Parp1, Adprp, Adprt, Adprt1
Domain Architecture
Description	Poly [ADP-ribose] polymerase 1 (EC 2.4.2.30) (PARP-1) (ADPRT) (NAD(+) ADP-ribosyltransferase 1) (Poly[ADP-ribose] synthetase 1) (msPARP).

PARP3_HUMAN
θ value	3.70236e-70 (rank : 5)	NC score	0.926769 (rank : 3)
Query Neighborhood Hits	33	Target Neighborhood Hits	30	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y6F1, Q8NER9, Q96CG2, Q9UG81	Gene names	PARP3, ADPRT3, ADPRTL3
Domain Architecture
Description	Poly [ADP-ribose] polymerase 3 (EC 2.4.2.30) (PARP-3) (NAD(+) ADP- ribosyltransferase 3) (Poly[ADP-ribose] synthetase 3) (pADPRT-3) (hPARP-3) (IRT1).

PARP4_HUMAN
θ value	3.75424e-22 (rank : 6)	NC score	0.566220 (rank : 6)
Query Neighborhood Hits	33	Target Neighborhood Hits	93	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UKK3, O75903, Q14682, Q9H1M6	Gene names	PARP4, ADPRTL1, KIAA0177, PARPL
Domain Architecture
Description	Poly [ADP-ribose] polymerase 4 (EC 2.4.2.30) (PARP-4) (Vault poly(ADP- ribose) polymerase) (VPARP) (193 kDa vault protein) (PARP- related/IalphaI-related H5/proline-rich) (PH5P).

TNKS1_HUMAN
θ value	0.00102713 (rank : 7)	NC score	0.072945 (rank : 12)
Query Neighborhood Hits	33	Target Neighborhood Hits	477	Shared Neighborhood Hits	10
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

PARP8_HUMAN
θ value	0.00390308 (rank : 8)	NC score	0.192209 (rank : 7)
Query Neighborhood Hits	33	Target Neighborhood Hits	22	Shared Neighborhood Hits	11
SwissProt Accessions	Q8N3A8, Q3KRB7, Q6DHZ1, Q9H754	Gene names	PARP8
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 8 (EC 2.4.2.30) (PARP-8).

PARP8_MOUSE
θ value	0.00390308 (rank : 9)	NC score	0.191937 (rank : 8)
Query Neighborhood Hits	33	Target Neighborhood Hits	25	Shared Neighborhood Hits	11
SwissProt Accessions	Q3UD82, Q3UDE4, Q3UDU5, Q8VCB5, Q9CYY3	Gene names	Parp8, D13Ertd275e
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 8 (EC 2.4.2.30) (PARP-8).

TNKS2_HUMAN
θ value	0.00869519 (rank : 10)	NC score	0.068075 (rank : 15)
Query Neighborhood Hits	33	Target Neighborhood Hits	361	Shared Neighborhood Hits	10
SwissProt Accessions	Q9H2K2, Q9H8F2, Q9HAS4	Gene names	TNKS2, PARP5B, TANK2, TNKL
Domain Architecture
Description	Tankyrase-2 (EC 2.4.2.30) (TANK2) (Tankyrase II) (TNKS-2) (TRF1- interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase-like protein) (Tankyrase-related protein).

PARP6_HUMAN
θ value	0.0148317 (rank : 11)	NC score	0.187971 (rank : 9)
Query Neighborhood Hits	33	Target Neighborhood Hits	16	Shared Neighborhood Hits	11
SwissProt Accessions	Q2NL67, Q9H7C5, Q9H9X6, Q9HAF3, Q9NPS6, Q9UFG4	Gene names	PARP6
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 6 (EC 2.4.2.30) (PARP-6).

PARP6_MOUSE
θ value	0.0148317 (rank : 12)	NC score	0.187957 (rank : 10)
Query Neighborhood Hits	33	Target Neighborhood Hits	17	Shared Neighborhood Hits	11
SwissProt Accessions	Q6P6P7, Q8BVW1	Gene names	Parp6
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 6 (EC 2.4.2.30) (PARP-6).

JAD1A_HUMAN
θ value	0.813845 (rank : 13)	NC score	0.021314 (rank : 25)
Query Neighborhood Hits	33	Target Neighborhood Hits	328	Shared Neighborhood Hits	4
SwissProt Accessions	P29375	Gene names	JARID1A, RBBP2, RBP2
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1A (Retinoblastoma-binding protein 2) (RBBP-2).

OSBP1_HUMAN
θ value	1.81305 (rank : 14)	NC score	0.013252 (rank : 29)
Query Neighborhood Hits	33	Target Neighborhood Hits	180	Shared Neighborhood Hits	2
SwissProt Accessions	P22059	Gene names	OSBP, OSBP1
Domain Architecture
Description	Oxysterol-binding protein 1.

PAR16_MOUSE
θ value	1.81305 (rank : 15)	NC score	0.067298 (rank : 16)
Query Neighborhood Hits	33	Target Neighborhood Hits	8	Shared Neighborhood Hits	7
SwissProt Accessions	Q7TMM8, Q3V031, Q8CC71	Gene names	Parp16
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 16 (EC 2.4.2.30) (PARP-16).

PARPT_MOUSE
θ value	1.81305 (rank : 16)	NC score	0.080700 (rank : 11)
Query Neighborhood Hits	33	Target Neighborhood Hits	47	Shared Neighborhood Hits	9
SwissProt Accessions	Q8C1B2, Q3UD50, Q8C032	Gene names	Tiparp
Domain Architecture	No domain graphic available
Description	TCDD-inducible poly [ADP-ribose] polymerase (EC 2.4.2.30).

CK5P2_HUMAN
θ value	2.36792 (rank : 17)	NC score	0.007018 (rank : 34)
Query Neighborhood Hits	33	Target Neighborhood Hits	1433	Shared Neighborhood Hits	9
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

DDX46_MOUSE
θ value	2.36792 (rank : 18)	NC score	0.009465 (rank : 31)
Query Neighborhood Hits	33	Target Neighborhood Hits	358	Shared Neighborhood Hits	5
SwissProt Accessions	Q569Z5, Q6ZQ42, Q8R0R6	Gene names	Ddx46, Kiaa0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46).

PARPT_HUMAN
θ value	2.36792 (rank : 19)	NC score	0.064402 (rank : 17)
Query Neighborhood Hits	33	Target Neighborhood Hits	36	Shared Neighborhood Hits	8
SwissProt Accessions	Q7Z3E1, Q68CY9, Q86VP4, Q9Y4P7	Gene names	TIPARP, PARP7
Domain Architecture	No domain graphic available
Description	TCDD-inducible poly [ADP-ribose] polymerase (EC 2.4.2.30) (Poly [ADP- ribose] polymerase 7) (PARP-7).

THUM1_HUMAN
θ value	2.36792 (rank : 20)	NC score	0.026680 (rank : 23)
Query Neighborhood Hits	33	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NXG2, Q9BWC3	Gene names	THUMPD1
Domain Architecture
Description	THUMP domain-containing protein 1.

MYO5C_HUMAN
θ value	3.0926 (rank : 21)	NC score	0.004967 (rank : 35)
Query Neighborhood Hits	33	Target Neighborhood Hits	1206	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

FLOT2_HUMAN
θ value	4.03905 (rank : 22)	NC score	0.032699 (rank : 21)
Query Neighborhood Hits	33	Target Neighborhood Hits	87	Shared Neighborhood Hits	4
SwissProt Accessions	Q14254	Gene names	FLOT2, ESA1, M17S1
Domain Architecture
Description	Flotillin-2 (Epidermal surface antigen) (ESA).

FLOT2_MOUSE
θ value	4.03905 (rank : 23)	NC score	0.032659 (rank : 22)
Query Neighborhood Hits	33	Target Neighborhood Hits	90	Shared Neighborhood Hits	4
SwissProt Accessions	Q60634, Q6NS75	Gene names	Flot2, Esa1, M17s1
Domain Architecture
Description	Flotillin-2 (Epidermal surface antigen) (ESA).

CP007_HUMAN
θ value	5.27518 (rank : 24)	NC score	0.024840 (rank : 24)
Query Neighborhood Hits	33	Target Neighborhood Hits	85	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y2B5	Gene names	C16orf7, ATPBL
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf7 (Protein ATP-BL).

DDX46_HUMAN
θ value	5.27518 (rank : 25)	NC score	0.008296 (rank : 32)
Query Neighborhood Hits	33	Target Neighborhood Hits	357	Shared Neighborhood Hits	5
SwissProt Accessions	Q7L014, O94894, Q96EI0, Q9Y658	Gene names	DDX46, KIAA0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46) (PRP5 homolog).

CAPS1_HUMAN
θ value	6.88961 (rank : 26)	NC score	0.013384 (rank : 28)
Query Neighborhood Hits	33	Target Neighborhood Hits	86	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ULU8, Q13339, Q6GQQ6, Q8N2Z5, Q8N3M7, Q8NFR0, Q96BC2	Gene names	CADPS, CAPS, CAPS1, KIAA1121
Domain Architecture	No domain graphic available
Description	Calcium-dependent secretion activator 1 (Calcium-dependent activator protein for secretion 1) (CAPS-1).

CP007_MOUSE
θ value	6.88961 (rank : 27)	NC score	0.019579 (rank : 26)
Query Neighborhood Hits	33	Target Neighborhood Hits	231	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C190, Q6PFD1	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf7 homolog (5-day ovary-specific transcript 1 protein).

PAR16_HUMAN
θ value	6.88961 (rank : 28)	NC score	0.059217 (rank : 19)
Query Neighborhood Hits	33	Target Neighborhood Hits	9	Shared Neighborhood Hits	7
SwissProt Accessions	Q8N5Y8, Q6PK64, Q9NX03	Gene names	PARP16
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 16 (EC 2.4.2.30) (PARP-16).

ZN396_HUMAN
θ value	6.88961 (rank : 29)	NC score	-0.000648 (rank : 37)
Query Neighborhood Hits	33	Target Neighborhood Hits	703	Shared Neighborhood Hits	2
SwissProt Accessions	Q96N95, Q8NF98, Q8TD80	Gene names	ZNF396, ZSCAN14
Domain Architecture
Description	Zinc finger protein 396 (Zinc finger and SCAN domain-containing protein 14).

ZNFX1_HUMAN
θ value	6.88961 (rank : 30)	NC score	0.007930 (rank : 33)
Query Neighborhood Hits	33	Target Neighborhood Hits	308	Shared Neighborhood Hits	2
SwissProt Accessions	Q9P2E3, Q9BQM7, Q9BQM8, Q9H8C1, Q9H9S2, Q9NUM1, Q9NWW1	Gene names	ZNFX1, KIAA1404
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

41_HUMAN
θ value	8.99809 (rank : 31)	NC score	0.003776 (rank : 36)
Query Neighborhood Hits	33	Target Neighborhood Hits	157	Shared Neighborhood Hits	3
SwissProt Accessions	P11171, P11176, Q14245, Q5TB35, Q5VXN8, Q8IXV9, Q9Y578, Q9Y579	Gene names	EPB41, E41P
Domain Architecture
Description	Protein 4.1 (Band 4.1) (P4.1) (EPB4.1) (4.1R).

CAPS1_MOUSE
θ value	8.99809 (rank : 32)	NC score	0.012582 (rank : 30)
Query Neighborhood Hits	33	Target Neighborhood Hits	93	Shared Neighborhood Hits	4
SwissProt Accessions	Q80TJ1, Q3TSP2, Q61374, Q6AXB4, Q6PGF0	Gene names	Cadps, Caps, Caps1, Kiaa1121
Domain Architecture	No domain graphic available
Description	Calcium-dependent secretion activator 1 (Calcium-dependent activator protein for secretion 1) (CAPS-1).

CIP1_HUMAN
θ value	8.99809 (rank : 33)	NC score	0.017094 (rank : 27)
Query Neighborhood Hits	33	Target Neighborhood Hits	83	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NPC3	Gene names	CCNB1IP1, C14orf18, HEI10
Domain Architecture	No domain graphic available
Description	Cyclin-B1-interacting protein 1 (EC 6.3.2.-) (Human enhancer of invasion 10) (E3 ubiquitin-protein ligase HEI10).

DNL3_HUMAN
θ value	θ > 10 (rank : 34)	NC score	0.071019 (rank : 13)
Query Neighborhood Hits	33	Target Neighborhood Hits	49	Shared Neighborhood Hits	2
SwissProt Accessions	P49916, Q16714	Gene names	LIG3
Domain Architecture
Description	DNA ligase 3 (EC 6.5.1.1) (DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3).

DNL3_MOUSE
θ value	θ > 10 (rank : 35)	NC score	0.069124 (rank : 14)
Query Neighborhood Hits	33	Target Neighborhood Hits	37	Shared Neighborhood Hits	2
SwissProt Accessions	P97386, P97385	Gene names	Lig3
Domain Architecture
Description	DNA ligase 3 (EC 6.5.1.1) (DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3).

LHR2A_HUMAN
θ value	θ > 10 (rank : 36)	NC score	0.055724 (rank : 20)
Query Neighborhood Hits	33	Target Neighborhood Hits	16	Shared Neighborhood Hits	1
SwissProt Accessions	O00534, Q6UN19, Q6UN20, Q9BVF8	Gene names	LOH11CR2A, BCSC1
Domain Architecture
Description	Loss of heterozygosity 11 chromosomal region 2 gene A protein (Breast cancer suppressor candidate 1) (BCSC-1).

LHR2A_MOUSE
θ value	θ > 10 (rank : 37)	NC score	0.059303 (rank : 18)
Query Neighborhood Hits	33	Target Neighborhood Hits	16	Shared Neighborhood Hits	1
SwissProt Accessions	Q99KC8, Q3TTU2, Q6UN22, Q8BHA8, Q9CTV9	Gene names	Loh11cr2a
Domain Architecture
Description	Loss of heterozygosity 11 chromosomal region 2 gene A protein homolog.

Hits sorted by NC score

PARP2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	33	Target Neighborhood Hits	33	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UGN5, Q8TEU4, Q9NUV2, Q9UMR4, Q9Y6C8	Gene names	PARP2, ADPRT2, ADPRTL2
Domain Architecture
Description	Poly [ADP-ribose] polymerase 2 (EC 2.4.2.30) (PARP-2) (NAD(+) ADP- ribosyltransferase 2) (Poly[ADP-ribose] synthetase 2) (pADPRT-2) (hPARP-2).

PARP2_MOUSE
NC score	0.991472 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	33	Target Neighborhood Hits	53	Shared Neighborhood Hits	18
SwissProt Accessions	O88554, Q99N29	Gene names	Parp2, Adprt2, Adprtl2, Aspartl2
Domain Architecture
Description	Poly [ADP-ribose] polymerase 2 (EC 2.4.2.30) (PARP-2) (NAD(+) ADP- ribosyltransferase 2) (Poly[ADP-ribose] synthetase 2) (pADPRT-2) (mPARP-2).

PARP3_HUMAN
NC score	0.926769 (rank : 3)	θ value	3.70236e-70 (rank : 5)
Query Neighborhood Hits	33	Target Neighborhood Hits	30	Shared Neighborhood Hits	13
SwissProt Accessions	Q9Y6F1, Q8NER9, Q96CG2, Q9UG81	Gene names	PARP3, ADPRT3, ADPRTL3
Domain Architecture
Description	Poly [ADP-ribose] polymerase 3 (EC 2.4.2.30) (PARP-3) (NAD(+) ADP- ribosyltransferase 3) (Poly[ADP-ribose] synthetase 3) (pADPRT-3) (hPARP-3) (IRT1).

PARP1_HUMAN
NC score	0.920451 (rank : 4)	θ value	8.73085e-104 (rank : 3)
Query Neighborhood Hits	33	Target Neighborhood Hits	54	Shared Neighborhood Hits	14
SwissProt Accessions	P09874, Q8IUZ9	Gene names	PARP1, ADPRT, PPOL
Domain Architecture
Description	Poly [ADP-ribose] polymerase 1 (EC 2.4.2.30) (PARP-1) (ADPRT) (NAD(+) ADP-ribosyltransferase 1) (Poly[ADP-ribose] synthetase 1).

PARP1_MOUSE
NC score	0.910424 (rank : 5)	θ value	2.80862e-102 (rank : 4)
Query Neighborhood Hits	33	Target Neighborhood Hits	102	Shared Neighborhood Hits	15
SwissProt Accessions	P11103, Q9JLX4, Q9QVQ3	Gene names	Parp1, Adprp, Adprt, Adprt1
Domain Architecture
Description	Poly [ADP-ribose] polymerase 1 (EC 2.4.2.30) (PARP-1) (ADPRT) (NAD(+) ADP-ribosyltransferase 1) (Poly[ADP-ribose] synthetase 1) (msPARP).

PARP4_HUMAN
NC score	0.566220 (rank : 6)	θ value	3.75424e-22 (rank : 6)
Query Neighborhood Hits	33	Target Neighborhood Hits	93	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UKK3, O75903, Q14682, Q9H1M6	Gene names	PARP4, ADPRTL1, KIAA0177, PARPL
Domain Architecture
Description	Poly [ADP-ribose] polymerase 4 (EC 2.4.2.30) (PARP-4) (Vault poly(ADP- ribose) polymerase) (VPARP) (193 kDa vault protein) (PARP- related/IalphaI-related H5/proline-rich) (PH5P).

PARP8_HUMAN
NC score	0.192209 (rank : 7)	θ value	0.00390308 (rank : 8)
Query Neighborhood Hits	33	Target Neighborhood Hits	22	Shared Neighborhood Hits	11
SwissProt Accessions	Q8N3A8, Q3KRB7, Q6DHZ1, Q9H754	Gene names	PARP8
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 8 (EC 2.4.2.30) (PARP-8).

PARP8_MOUSE
NC score	0.191937 (rank : 8)	θ value	0.00390308 (rank : 9)
Query Neighborhood Hits	33	Target Neighborhood Hits	25	Shared Neighborhood Hits	11
SwissProt Accessions	Q3UD82, Q3UDE4, Q3UDU5, Q8VCB5, Q9CYY3	Gene names	Parp8, D13Ertd275e
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 8 (EC 2.4.2.30) (PARP-8).

PARP6_HUMAN
NC score	0.187971 (rank : 9)	θ value	0.0148317 (rank : 11)
Query Neighborhood Hits	33	Target Neighborhood Hits	16	Shared Neighborhood Hits	11
SwissProt Accessions	Q2NL67, Q9H7C5, Q9H9X6, Q9HAF3, Q9NPS6, Q9UFG4	Gene names	PARP6
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 6 (EC 2.4.2.30) (PARP-6).

PARP6_MOUSE
NC score	0.187957 (rank : 10)	θ value	0.0148317 (rank : 12)
Query Neighborhood Hits	33	Target Neighborhood Hits	17	Shared Neighborhood Hits	11
SwissProt Accessions	Q6P6P7, Q8BVW1	Gene names	Parp6
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 6 (EC 2.4.2.30) (PARP-6).

PARPT_MOUSE
NC score	0.080700 (rank : 11)	θ value	1.81305 (rank : 16)
Query Neighborhood Hits	33	Target Neighborhood Hits	47	Shared Neighborhood Hits	9
SwissProt Accessions	Q8C1B2, Q3UD50, Q8C032	Gene names	Tiparp
Domain Architecture	No domain graphic available
Description	TCDD-inducible poly [ADP-ribose] polymerase (EC 2.4.2.30).

TNKS1_HUMAN
NC score	0.072945 (rank : 12)	θ value	0.00102713 (rank : 7)
Query Neighborhood Hits	33	Target Neighborhood Hits	477	Shared Neighborhood Hits	10
SwissProt Accessions	O95271, O95272	Gene names	TNKS, PARP5A, PARPL, TIN1, TINF1, TNKS1
Domain Architecture
Description	Tankyrase-1 (EC 2.4.2.30) (TANK1) (Tankyrase I) (TNKS-1) (TRF1- interacting ankyrin-related ADP-ribose polymerase).

DNL3_HUMAN
NC score	0.071019 (rank : 13)	θ value	θ > 10 (rank : 34)
Query Neighborhood Hits	33	Target Neighborhood Hits	49	Shared Neighborhood Hits	2
SwissProt Accessions	P49916, Q16714	Gene names	LIG3
Domain Architecture
Description	DNA ligase 3 (EC 6.5.1.1) (DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3).

DNL3_MOUSE
NC score	0.069124 (rank : 14)	θ value	θ > 10 (rank : 35)
Query Neighborhood Hits	33	Target Neighborhood Hits	37	Shared Neighborhood Hits	2
SwissProt Accessions	P97386, P97385	Gene names	Lig3
Domain Architecture
Description	DNA ligase 3 (EC 6.5.1.1) (DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3).

TNKS2_HUMAN
NC score	0.068075 (rank : 15)	θ value	0.00869519 (rank : 10)
Query Neighborhood Hits	33	Target Neighborhood Hits	361	Shared Neighborhood Hits	10
SwissProt Accessions	Q9H2K2, Q9H8F2, Q9HAS4	Gene names	TNKS2, PARP5B, TANK2, TNKL
Domain Architecture
Description	Tankyrase-2 (EC 2.4.2.30) (TANK2) (Tankyrase II) (TNKS-2) (TRF1- interacting ankyrin-related ADP-ribose polymerase 2) (Tankyrase-like protein) (Tankyrase-related protein).

PAR16_MOUSE
NC score	0.067298 (rank : 16)	θ value	1.81305 (rank : 15)
Query Neighborhood Hits	33	Target Neighborhood Hits	8	Shared Neighborhood Hits	7
SwissProt Accessions	Q7TMM8, Q3V031, Q8CC71	Gene names	Parp16
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 16 (EC 2.4.2.30) (PARP-16).

PARPT_HUMAN
NC score	0.064402 (rank : 17)	θ value	2.36792 (rank : 19)
Query Neighborhood Hits	33	Target Neighborhood Hits	36	Shared Neighborhood Hits	8
SwissProt Accessions	Q7Z3E1, Q68CY9, Q86VP4, Q9Y4P7	Gene names	TIPARP, PARP7
Domain Architecture	No domain graphic available
Description	TCDD-inducible poly [ADP-ribose] polymerase (EC 2.4.2.30) (Poly [ADP- ribose] polymerase 7) (PARP-7).

LHR2A_MOUSE
NC score	0.059303 (rank : 18)	θ value	θ > 10 (rank : 37)
Query Neighborhood Hits	33	Target Neighborhood Hits	16	Shared Neighborhood Hits	1
SwissProt Accessions	Q99KC8, Q3TTU2, Q6UN22, Q8BHA8, Q9CTV9	Gene names	Loh11cr2a
Domain Architecture
Description	Loss of heterozygosity 11 chromosomal region 2 gene A protein homolog.

PAR16_HUMAN
NC score	0.059217 (rank : 19)	θ value	6.88961 (rank : 28)
Query Neighborhood Hits	33	Target Neighborhood Hits	9	Shared Neighborhood Hits	7
SwissProt Accessions	Q8N5Y8, Q6PK64, Q9NX03	Gene names	PARP16
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 16 (EC 2.4.2.30) (PARP-16).

LHR2A_HUMAN
NC score	0.055724 (rank : 20)	θ value	θ > 10 (rank : 36)
Query Neighborhood Hits	33	Target Neighborhood Hits	16	Shared Neighborhood Hits	1
SwissProt Accessions	O00534, Q6UN19, Q6UN20, Q9BVF8	Gene names	LOH11CR2A, BCSC1
Domain Architecture
Description	Loss of heterozygosity 11 chromosomal region 2 gene A protein (Breast cancer suppressor candidate 1) (BCSC-1).

FLOT2_HUMAN
NC score	0.032699 (rank : 21)	θ value	4.03905 (rank : 22)
Query Neighborhood Hits	33	Target Neighborhood Hits	87	Shared Neighborhood Hits	4
SwissProt Accessions	Q14254	Gene names	FLOT2, ESA1, M17S1
Domain Architecture
Description	Flotillin-2 (Epidermal surface antigen) (ESA).

FLOT2_MOUSE
NC score	0.032659 (rank : 22)	θ value	4.03905 (rank : 23)
Query Neighborhood Hits	33	Target Neighborhood Hits	90	Shared Neighborhood Hits	4
SwissProt Accessions	Q60634, Q6NS75	Gene names	Flot2, Esa1, M17s1
Domain Architecture
Description	Flotillin-2 (Epidermal surface antigen) (ESA).

THUM1_HUMAN
NC score	0.026680 (rank : 23)	θ value	2.36792 (rank : 20)
Query Neighborhood Hits	33	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NXG2, Q9BWC3	Gene names	THUMPD1
Domain Architecture
Description	THUMP domain-containing protein 1.

CP007_HUMAN
NC score	0.024840 (rank : 24)	θ value	5.27518 (rank : 24)
Query Neighborhood Hits	33	Target Neighborhood Hits	85	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y2B5	Gene names	C16orf7, ATPBL
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf7 (Protein ATP-BL).

JAD1A_HUMAN
NC score	0.021314 (rank : 25)	θ value	0.813845 (rank : 13)
Query Neighborhood Hits	33	Target Neighborhood Hits	328	Shared Neighborhood Hits	4
SwissProt Accessions	P29375	Gene names	JARID1A, RBBP2, RBP2
Domain Architecture
Description	Jumonji/ARID domain-containing protein 1A (Retinoblastoma-binding protein 2) (RBBP-2).

CP007_MOUSE
NC score	0.019579 (rank : 26)	θ value	6.88961 (rank : 27)
Query Neighborhood Hits	33	Target Neighborhood Hits	231	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C190, Q6PFD1	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf7 homolog (5-day ovary-specific transcript 1 protein).

CIP1_HUMAN
NC score	0.017094 (rank : 27)	θ value	8.99809 (rank : 33)
Query Neighborhood Hits	33	Target Neighborhood Hits	83	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NPC3	Gene names	CCNB1IP1, C14orf18, HEI10
Domain Architecture	No domain graphic available
Description	Cyclin-B1-interacting protein 1 (EC 6.3.2.-) (Human enhancer of invasion 10) (E3 ubiquitin-protein ligase HEI10).

CAPS1_HUMAN
NC score	0.013384 (rank : 28)	θ value	6.88961 (rank : 26)
Query Neighborhood Hits	33	Target Neighborhood Hits	86	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ULU8, Q13339, Q6GQQ6, Q8N2Z5, Q8N3M7, Q8NFR0, Q96BC2	Gene names	CADPS, CAPS, CAPS1, KIAA1121
Domain Architecture	No domain graphic available
Description	Calcium-dependent secretion activator 1 (Calcium-dependent activator protein for secretion 1) (CAPS-1).

OSBP1_HUMAN
NC score	0.013252 (rank : 29)	θ value	1.81305 (rank : 14)
Query Neighborhood Hits	33	Target Neighborhood Hits	180	Shared Neighborhood Hits	2
SwissProt Accessions	P22059	Gene names	OSBP, OSBP1
Domain Architecture
Description	Oxysterol-binding protein 1.

CAPS1_MOUSE
NC score	0.012582 (rank : 30)	θ value	8.99809 (rank : 32)
Query Neighborhood Hits	33	Target Neighborhood Hits	93	Shared Neighborhood Hits	4
SwissProt Accessions	Q80TJ1, Q3TSP2, Q61374, Q6AXB4, Q6PGF0	Gene names	Cadps, Caps, Caps1, Kiaa1121
Domain Architecture	No domain graphic available
Description	Calcium-dependent secretion activator 1 (Calcium-dependent activator protein for secretion 1) (CAPS-1).

DDX46_MOUSE
NC score	0.009465 (rank : 31)	θ value	2.36792 (rank : 18)
Query Neighborhood Hits	33	Target Neighborhood Hits	358	Shared Neighborhood Hits	5
SwissProt Accessions	Q569Z5, Q6ZQ42, Q8R0R6	Gene names	Ddx46, Kiaa0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46).

DDX46_HUMAN
NC score	0.008296 (rank : 32)	θ value	5.27518 (rank : 25)
Query Neighborhood Hits	33	Target Neighborhood Hits	357	Shared Neighborhood Hits	5
SwissProt Accessions	Q7L014, O94894, Q96EI0, Q9Y658	Gene names	DDX46, KIAA0801
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DDX46 (EC 3.6.1.-) (DEAD box protein 46) (PRP5 homolog).

ZNFX1_HUMAN
NC score	0.007930 (rank : 33)	θ value	6.88961 (rank : 30)
Query Neighborhood Hits	33	Target Neighborhood Hits	308	Shared Neighborhood Hits	2
SwissProt Accessions	Q9P2E3, Q9BQM7, Q9BQM8, Q9H8C1, Q9H9S2, Q9NUM1, Q9NWW1	Gene names	ZNFX1, KIAA1404
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

CK5P2_HUMAN
NC score	0.007018 (rank : 34)	θ value	2.36792 (rank : 17)
Query Neighborhood Hits	33	Target Neighborhood Hits	1433	Shared Neighborhood Hits	9
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

MYO5C_HUMAN
NC score	0.004967 (rank : 35)	θ value	3.0926 (rank : 21)
Query Neighborhood Hits	33	Target Neighborhood Hits	1206	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

41_HUMAN
NC score	0.003776 (rank : 36)	θ value	8.99809 (rank : 31)
Query Neighborhood Hits	33	Target Neighborhood Hits	157	Shared Neighborhood Hits	3
SwissProt Accessions	P11171, P11176, Q14245, Q5TB35, Q5VXN8, Q8IXV9, Q9Y578, Q9Y579	Gene names	EPB41, E41P
Domain Architecture
Description	Protein 4.1 (Band 4.1) (P4.1) (EPB4.1) (4.1R).

ZN396_HUMAN
NC score	-0.000648 (rank : 37)	θ value	6.88961 (rank : 29)
Query Neighborhood Hits	33	Target Neighborhood Hits	703	Shared Neighborhood Hits	2
SwissProt Accessions	Q96N95, Q8NF98, Q8TD80	Gene names	ZNF396, ZSCAN14
Domain Architecture
Description	Zinc finger protein 396 (Zinc finger and SCAN domain-containing protein 14).