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Network neighborhood for query Sequence : PARP8_HUMAN

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PARP8_HUMAN
SwissProt Accessions	Q8N3A8, Q3KRB7, Q6DHZ1, Q9H754	Gene names	PARP8
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 8 (EC 2.4.2.30) (PARP-8).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PARP8_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	22	Target Neighborhood Hits	22	Shared Neighborhood Hits	22
SwissProt Accessions	Q8N3A8, Q3KRB7, Q6DHZ1, Q9H754	Gene names	PARP8
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 8 (EC 2.4.2.30) (PARP-8).

PARP8_MOUSE
θ value	0 (rank : 2)	NC score	0.997757 (rank : 2)
Query Neighborhood Hits	22	Target Neighborhood Hits	25	Shared Neighborhood Hits	16
SwissProt Accessions	Q3UD82, Q3UDE4, Q3UDU5, Q8VCB5, Q9CYY3	Gene names	Parp8, D13Ertd275e
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 8 (EC 2.4.2.30) (PARP-8).

PARP6_HUMAN
θ value	1.62005e-158 (rank : 3)	NC score	0.966588 (rank : 3)
Query Neighborhood Hits	22	Target Neighborhood Hits	16	Shared Neighborhood Hits	11
SwissProt Accessions	Q2NL67, Q9H7C5, Q9H9X6, Q9HAF3, Q9NPS6, Q9UFG4	Gene names	PARP6
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 6 (EC 2.4.2.30) (PARP-6).

PARP6_MOUSE
θ value	8.04023e-158 (rank : 4)	NC score	0.966323 (rank : 4)
Query Neighborhood Hits	22	Target Neighborhood Hits	17	Shared Neighborhood Hits	11
SwissProt Accessions	Q6P6P7, Q8BVW1	Gene names	Parp6
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 6 (EC 2.4.2.30) (PARP-6).

PAR16_MOUSE
θ value	5.26297e-08 (rank : 5)	NC score	0.436592 (rank : 5)
Query Neighborhood Hits	22	Target Neighborhood Hits	8	Shared Neighborhood Hits	7
SwissProt Accessions	Q7TMM8, Q3V031, Q8CC71	Gene names	Parp16
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 16 (EC 2.4.2.30) (PARP-16).

PAR16_HUMAN
θ value	7.59969e-07 (rank : 6)	NC score	0.428649 (rank : 6)
Query Neighborhood Hits	22	Target Neighborhood Hits	9	Shared Neighborhood Hits	7
SwissProt Accessions	Q8N5Y8, Q6PK64, Q9NX03	Gene names	PARP16
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 16 (EC 2.4.2.30) (PARP-16).

PARP2_MOUSE
θ value	0.00228821 (rank : 7)	NC score	0.188001 (rank : 8)
Query Neighborhood Hits	22	Target Neighborhood Hits	53	Shared Neighborhood Hits	9
SwissProt Accessions	O88554, Q99N29	Gene names	Parp2, Adprt2, Adprtl2, Aspartl2
Domain Architecture
Description	Poly [ADP-ribose] polymerase 2 (EC 2.4.2.30) (PARP-2) (NAD(+) ADP- ribosyltransferase 2) (Poly[ADP-ribose] synthetase 2) (pADPRT-2) (mPARP-2).

PARP2_HUMAN
θ value	0.00390308 (rank : 8)	NC score	0.192209 (rank : 7)
Query Neighborhood Hits	22	Target Neighborhood Hits	33	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UGN5, Q8TEU4, Q9NUV2, Q9UMR4, Q9Y6C8	Gene names	PARP2, ADPRT2, ADPRTL2
Domain Architecture
Description	Poly [ADP-ribose] polymerase 2 (EC 2.4.2.30) (PARP-2) (NAD(+) ADP- ribosyltransferase 2) (Poly[ADP-ribose] synthetase 2) (pADPRT-2) (hPARP-2).

PARP1_HUMAN
θ value	0.0961366 (rank : 9)	NC score	0.148056 (rank : 9)
Query Neighborhood Hits	22	Target Neighborhood Hits	54	Shared Neighborhood Hits	9
SwissProt Accessions	P09874, Q8IUZ9	Gene names	PARP1, ADPRT, PPOL
Domain Architecture
Description	Poly [ADP-ribose] polymerase 1 (EC 2.4.2.30) (PARP-1) (ADPRT) (NAD(+) ADP-ribosyltransferase 1) (Poly[ADP-ribose] synthetase 1).

PARP1_MOUSE
θ value	0.163984 (rank : 10)	NC score	0.140123 (rank : 10)
Query Neighborhood Hits	22	Target Neighborhood Hits	102	Shared Neighborhood Hits	10
SwissProt Accessions	P11103, Q9JLX4, Q9QVQ3	Gene names	Parp1, Adprp, Adprt, Adprt1
Domain Architecture
Description	Poly [ADP-ribose] polymerase 1 (EC 2.4.2.30) (PARP-1) (ADPRT) (NAD(+) ADP-ribosyltransferase 1) (Poly[ADP-ribose] synthetase 1) (msPARP).

PARP3_HUMAN
θ value	1.38821 (rank : 11)	NC score	0.138226 (rank : 11)
Query Neighborhood Hits	22	Target Neighborhood Hits	30	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y6F1, Q8NER9, Q96CG2, Q9UG81	Gene names	PARP3, ADPRT3, ADPRTL3
Domain Architecture
Description	Poly [ADP-ribose] polymerase 3 (EC 2.4.2.30) (PARP-3) (NAD(+) ADP- ribosyltransferase 3) (Poly[ADP-ribose] synthetase 3) (pADPRT-3) (hPARP-3) (IRT1).

PENK_MOUSE
θ value	2.36792 (rank : 12)	NC score	0.041139 (rank : 12)
Query Neighborhood Hits	22	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	P22005	Gene names	Penk, Penk1
Domain Architecture
Description	Proenkephalin A precursor [Contains: Synenkephalin; Met-enkephalin (Opioid growth factor) (OGF); Met-enkephalin-Arg-Ser-Leu; Leu- enkephalin; Met-enkephalin-Arg-Phe].

ZBED1_HUMAN
θ value	2.36792 (rank : 13)	NC score	0.030919 (rank : 13)
Query Neighborhood Hits	22	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	O96006, Q96BY4	Gene names	ZBED1, ALTE, DREF, KIAA0785, TRAMP
Domain Architecture
Description	Zinc finger BED domain-containing protein 1 (dREF homolog) (Putative Ac-like transposable element).

LIPB1_HUMAN
θ value	4.03905 (rank : 14)	NC score	0.018868 (rank : 14)
Query Neighborhood Hits	22	Target Neighborhood Hits	640	Shared Neighborhood Hits	4
SwissProt Accessions	Q86W92, O75336, Q86X70, Q9NY03, Q9ULJ0	Gene names	PPFIBP1, KIAA1230
Domain Architecture
Description	Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1) (hSGT2).

ATS17_HUMAN
θ value	5.27518 (rank : 15)	NC score	0.008198 (rank : 20)
Query Neighborhood Hits	22	Target Neighborhood Hits	194	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TE56	Gene names	ADAMTS17
Domain Architecture
Description	ADAMTS-17 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 17) (ADAM-TS 17) (ADAM-TS17).

CTNA2_HUMAN
θ value	5.27518 (rank : 16)	NC score	0.013421 (rank : 19)
Query Neighborhood Hits	22	Target Neighborhood Hits	74	Shared Neighborhood Hits	3
SwissProt Accessions	P26232, Q4ZFW1, Q53R26, Q53R33, Q53T67, Q53T71, Q53TM8, Q7Z3Y0	Gene names	CTNNA2, CAPR
Domain Architecture
Description	Catenin alpha-2 (Alpha-catenin-related protein) (Alpha N-catenin).

CTNA2_MOUSE
θ value	5.27518 (rank : 17)	NC score	0.013430 (rank : 18)
Query Neighborhood Hits	22	Target Neighborhood Hits	75	Shared Neighborhood Hits	3
SwissProt Accessions	Q61301, Q61300, Q6AXD1	Gene names	Ctnna2, Catna2
Domain Architecture
Description	Catenin alpha-2 (Alpha-catenin-related protein) (Alpha N-catenin).

SYNC_HUMAN
θ value	5.27518 (rank : 18)	NC score	0.013446 (rank : 17)
Query Neighborhood Hits	22	Target Neighborhood Hits	47	Shared Neighborhood Hits	2
SwissProt Accessions	O43776	Gene names	NARS, ASNS
Domain Architecture
Description	Asparaginyl-tRNA synthetase, cytoplasmic (EC 6.1.1.22) (Asparagine-- tRNA ligase) (AsnRS).

CF170_HUMAN
θ value	6.88961 (rank : 19)	NC score	0.017979 (rank : 15)
Query Neighborhood Hits	22	Target Neighborhood Hits	39	Shared Neighborhood Hits	2
SwissProt Accessions	Q96NH3, Q6ZMY4, Q6ZUR7, Q8NB47	Gene names	C6orf170
Domain Architecture	No domain graphic available
Description	Protein C6orf170.

DACH1_HUMAN
θ value	6.88961 (rank : 20)	NC score	0.016049 (rank : 16)
Query Neighborhood Hits	22	Target Neighborhood Hits	214	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UI36, O75523, O75687, Q5VYY3, Q5VYY4, Q96SG3, Q96SG4, Q9H524, Q9UMH4	Gene names	DACH1, DACH
Domain Architecture
Description	Dachshund homolog 1 (Dach1).

DHX37_HUMAN
θ value	6.88961 (rank : 21)	NC score	0.007724 (rank : 21)
Query Neighborhood Hits	22	Target Neighborhood Hits	133	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IY37, Q9BUI7, Q9P211	Gene names	DHX37, DDX37, KIAA1517
Domain Architecture
Description	Probable ATP-dependent RNA helicase DHX37 (EC 3.6.1.-) (DEAH box protein 37).

CF060_HUMAN
θ value	8.99809 (rank : 22)	NC score	0.003060 (rank : 22)
Query Neighborhood Hits	22	Target Neighborhood Hits	1270	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NB25, Q96GY8, Q9H851	Gene names	C6orf60
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf60.

Hits sorted by NC score

PARP8_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	22	Target Neighborhood Hits	22	Shared Neighborhood Hits	22
SwissProt Accessions	Q8N3A8, Q3KRB7, Q6DHZ1, Q9H754	Gene names	PARP8
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 8 (EC 2.4.2.30) (PARP-8).

PARP8_MOUSE
NC score	0.997757 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	22	Target Neighborhood Hits	25	Shared Neighborhood Hits	16
SwissProt Accessions	Q3UD82, Q3UDE4, Q3UDU5, Q8VCB5, Q9CYY3	Gene names	Parp8, D13Ertd275e
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 8 (EC 2.4.2.30) (PARP-8).

PARP6_HUMAN
NC score	0.966588 (rank : 3)	θ value	1.62005e-158 (rank : 3)
Query Neighborhood Hits	22	Target Neighborhood Hits	16	Shared Neighborhood Hits	11
SwissProt Accessions	Q2NL67, Q9H7C5, Q9H9X6, Q9HAF3, Q9NPS6, Q9UFG4	Gene names	PARP6
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 6 (EC 2.4.2.30) (PARP-6).

PARP6_MOUSE
NC score	0.966323 (rank : 4)	θ value	8.04023e-158 (rank : 4)
Query Neighborhood Hits	22	Target Neighborhood Hits	17	Shared Neighborhood Hits	11
SwissProt Accessions	Q6P6P7, Q8BVW1	Gene names	Parp6
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 6 (EC 2.4.2.30) (PARP-6).

PAR16_MOUSE
NC score	0.436592 (rank : 5)	θ value	5.26297e-08 (rank : 5)
Query Neighborhood Hits	22	Target Neighborhood Hits	8	Shared Neighborhood Hits	7
SwissProt Accessions	Q7TMM8, Q3V031, Q8CC71	Gene names	Parp16
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 16 (EC 2.4.2.30) (PARP-16).

PAR16_HUMAN
NC score	0.428649 (rank : 6)	θ value	7.59969e-07 (rank : 6)
Query Neighborhood Hits	22	Target Neighborhood Hits	9	Shared Neighborhood Hits	7
SwissProt Accessions	Q8N5Y8, Q6PK64, Q9NX03	Gene names	PARP16
Domain Architecture	No domain graphic available
Description	Poly [ADP-ribose] polymerase 16 (EC 2.4.2.30) (PARP-16).

PARP2_HUMAN
NC score	0.192209 (rank : 7)	θ value	0.00390308 (rank : 8)
Query Neighborhood Hits	22	Target Neighborhood Hits	33	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UGN5, Q8TEU4, Q9NUV2, Q9UMR4, Q9Y6C8	Gene names	PARP2, ADPRT2, ADPRTL2
Domain Architecture
Description	Poly [ADP-ribose] polymerase 2 (EC 2.4.2.30) (PARP-2) (NAD(+) ADP- ribosyltransferase 2) (Poly[ADP-ribose] synthetase 2) (pADPRT-2) (hPARP-2).

PARP2_MOUSE
NC score	0.188001 (rank : 8)	θ value	0.00228821 (rank : 7)
Query Neighborhood Hits	22	Target Neighborhood Hits	53	Shared Neighborhood Hits	9
SwissProt Accessions	O88554, Q99N29	Gene names	Parp2, Adprt2, Adprtl2, Aspartl2
Domain Architecture
Description	Poly [ADP-ribose] polymerase 2 (EC 2.4.2.30) (PARP-2) (NAD(+) ADP- ribosyltransferase 2) (Poly[ADP-ribose] synthetase 2) (pADPRT-2) (mPARP-2).

PARP1_HUMAN
NC score	0.148056 (rank : 9)	θ value	0.0961366 (rank : 9)
Query Neighborhood Hits	22	Target Neighborhood Hits	54	Shared Neighborhood Hits	9
SwissProt Accessions	P09874, Q8IUZ9	Gene names	PARP1, ADPRT, PPOL
Domain Architecture
Description	Poly [ADP-ribose] polymerase 1 (EC 2.4.2.30) (PARP-1) (ADPRT) (NAD(+) ADP-ribosyltransferase 1) (Poly[ADP-ribose] synthetase 1).

PARP1_MOUSE
NC score	0.140123 (rank : 10)	θ value	0.163984 (rank : 10)
Query Neighborhood Hits	22	Target Neighborhood Hits	102	Shared Neighborhood Hits	10
SwissProt Accessions	P11103, Q9JLX4, Q9QVQ3	Gene names	Parp1, Adprp, Adprt, Adprt1
Domain Architecture
Description	Poly [ADP-ribose] polymerase 1 (EC 2.4.2.30) (PARP-1) (ADPRT) (NAD(+) ADP-ribosyltransferase 1) (Poly[ADP-ribose] synthetase 1) (msPARP).

PARP3_HUMAN
NC score	0.138226 (rank : 11)	θ value	1.38821 (rank : 11)
Query Neighborhood Hits	22	Target Neighborhood Hits	30	Shared Neighborhood Hits	9
SwissProt Accessions	Q9Y6F1, Q8NER9, Q96CG2, Q9UG81	Gene names	PARP3, ADPRT3, ADPRTL3
Domain Architecture
Description	Poly [ADP-ribose] polymerase 3 (EC 2.4.2.30) (PARP-3) (NAD(+) ADP- ribosyltransferase 3) (Poly[ADP-ribose] synthetase 3) (pADPRT-3) (hPARP-3) (IRT1).

PENK_MOUSE
NC score	0.041139 (rank : 12)	θ value	2.36792 (rank : 12)
Query Neighborhood Hits	22	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	P22005	Gene names	Penk, Penk1
Domain Architecture
Description	Proenkephalin A precursor [Contains: Synenkephalin; Met-enkephalin (Opioid growth factor) (OGF); Met-enkephalin-Arg-Ser-Leu; Leu- enkephalin; Met-enkephalin-Arg-Phe].

ZBED1_HUMAN
NC score	0.030919 (rank : 13)	θ value	2.36792 (rank : 13)
Query Neighborhood Hits	22	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	O96006, Q96BY4	Gene names	ZBED1, ALTE, DREF, KIAA0785, TRAMP
Domain Architecture
Description	Zinc finger BED domain-containing protein 1 (dREF homolog) (Putative Ac-like transposable element).

LIPB1_HUMAN
NC score	0.018868 (rank : 14)	θ value	4.03905 (rank : 14)
Query Neighborhood Hits	22	Target Neighborhood Hits	640	Shared Neighborhood Hits	4
SwissProt Accessions	Q86W92, O75336, Q86X70, Q9NY03, Q9ULJ0	Gene names	PPFIBP1, KIAA1230
Domain Architecture
Description	Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1) (hSGT2).

CF170_HUMAN
NC score	0.017979 (rank : 15)	θ value	6.88961 (rank : 19)
Query Neighborhood Hits	22	Target Neighborhood Hits	39	Shared Neighborhood Hits	2
SwissProt Accessions	Q96NH3, Q6ZMY4, Q6ZUR7, Q8NB47	Gene names	C6orf170
Domain Architecture	No domain graphic available
Description	Protein C6orf170.

DACH1_HUMAN
NC score	0.016049 (rank : 16)	θ value	6.88961 (rank : 20)
Query Neighborhood Hits	22	Target Neighborhood Hits	214	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UI36, O75523, O75687, Q5VYY3, Q5VYY4, Q96SG3, Q96SG4, Q9H524, Q9UMH4	Gene names	DACH1, DACH
Domain Architecture
Description	Dachshund homolog 1 (Dach1).

SYNC_HUMAN
NC score	0.013446 (rank : 17)	θ value	5.27518 (rank : 18)
Query Neighborhood Hits	22	Target Neighborhood Hits	47	Shared Neighborhood Hits	2
SwissProt Accessions	O43776	Gene names	NARS, ASNS
Domain Architecture
Description	Asparaginyl-tRNA synthetase, cytoplasmic (EC 6.1.1.22) (Asparagine-- tRNA ligase) (AsnRS).

CTNA2_MOUSE
NC score	0.013430 (rank : 18)	θ value	5.27518 (rank : 17)
Query Neighborhood Hits	22	Target Neighborhood Hits	75	Shared Neighborhood Hits	3
SwissProt Accessions	Q61301, Q61300, Q6AXD1	Gene names	Ctnna2, Catna2
Domain Architecture
Description	Catenin alpha-2 (Alpha-catenin-related protein) (Alpha N-catenin).

CTNA2_HUMAN
NC score	0.013421 (rank : 19)	θ value	5.27518 (rank : 16)
Query Neighborhood Hits	22	Target Neighborhood Hits	74	Shared Neighborhood Hits	3
SwissProt Accessions	P26232, Q4ZFW1, Q53R26, Q53R33, Q53T67, Q53T71, Q53TM8, Q7Z3Y0	Gene names	CTNNA2, CAPR
Domain Architecture
Description	Catenin alpha-2 (Alpha-catenin-related protein) (Alpha N-catenin).

ATS17_HUMAN
NC score	0.008198 (rank : 20)	θ value	5.27518 (rank : 15)
Query Neighborhood Hits	22	Target Neighborhood Hits	194	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TE56	Gene names	ADAMTS17
Domain Architecture
Description	ADAMTS-17 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase with thrombospondin motifs 17) (ADAM-TS 17) (ADAM-TS17).

DHX37_HUMAN
NC score	0.007724 (rank : 21)	θ value	6.88961 (rank : 21)
Query Neighborhood Hits	22	Target Neighborhood Hits	133	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IY37, Q9BUI7, Q9P211	Gene names	DHX37, DDX37, KIAA1517
Domain Architecture
Description	Probable ATP-dependent RNA helicase DHX37 (EC 3.6.1.-) (DEAH box protein 37).

CF060_HUMAN
NC score	0.003060 (rank : 22)	θ value	8.99809 (rank : 22)
Query Neighborhood Hits	22	Target Neighborhood Hits	1270	Shared Neighborhood Hits	4
SwissProt Accessions	Q8NB25, Q96GY8, Q9H851	Gene names	C6orf60
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf60.