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Network neighborhood for query Sequence : CP007_HUMAN

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CP007_HUMAN
SwissProt Accessions	Q9Y2B5	Gene names	C16orf7, ATPBL
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf7 (Protein ATP-BL).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CP007_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	85	Target Neighborhood Hits	85	Shared Neighborhood Hits	85
SwissProt Accessions	Q9Y2B5	Gene names	C16orf7, ATPBL
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf7 (Protein ATP-BL).

CP007_MOUSE
θ value	1.20704e-137 (rank : 2)	NC score	0.862119 (rank : 2)
Query Neighborhood Hits	85	Target Neighborhood Hits	231	Shared Neighborhood Hits	34
SwissProt Accessions	Q8C190, Q6PFD1	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf7 homolog (5-day ovary-specific transcript 1 protein).

CF182_MOUSE
θ value	0.279714 (rank : 3)	NC score	0.074919 (rank : 6)
Query Neighborhood Hits	85	Target Neighborhood Hits	551	Shared Neighborhood Hits	43
SwissProt Accessions	Q8VDS7, Q9CZE0, Q9D5A1	Gene names
Domain Architecture	No domain graphic available
Description	Protein C6orf182 homolog.

IL4RA_MOUSE
θ value	0.279714 (rank : 4)	NC score	0.060377 (rank : 17)
Query Neighborhood Hits	85	Target Neighborhood Hits	194	Shared Neighborhood Hits	4
SwissProt Accessions	P16382, O54690, Q60583, Q8CBW5	Gene names	Il4r, Il4ra
Domain Architecture
Description	Interleukin-4 receptor alpha chain precursor (IL-4R-alpha) (CD124 antigen) [Contains: Soluble interleukin-4 receptor alpha chain (IL-4- binding protein) (IL4-BP)].

CCHCR_HUMAN
θ value	0.365318 (rank : 5)	NC score	0.068960 (rank : 9)
Query Neighborhood Hits	85	Target Neighborhood Hits	717	Shared Neighborhood Hits	45
SwissProt Accessions	Q8TD31, Q9NRK8, Q9NWY9, Q9NXJ4, Q9NXK3, Q9Y6W1, Q9Y6W2	Gene names	CCHCR1, C6orf18, HCR
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein) (Putative gene 8 protein) (Pg8).

AMOL2_HUMAN
θ value	0.47712 (rank : 6)	NC score	0.081957 (rank : 4)
Query Neighborhood Hits	85	Target Neighborhood Hits	603	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y2J4, Q53EP1, Q96F99, Q9UKB4	Gene names	AMOTL2, KIAA0989
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 2 (Leman coiled-coil protein) (LCCP).

CAF1A_MOUSE
θ value	0.47712 (rank : 7)	NC score	0.071636 (rank : 7)
Query Neighborhood Hits	85	Target Neighborhood Hits	736	Shared Neighborhood Hits	38
SwissProt Accessions	Q9QWF0	Gene names	Chaf1a, Caip150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

G45IP_MOUSE
θ value	0.47712 (rank : 8)	NC score	0.100759 (rank : 3)
Query Neighborhood Hits	85	Target Neighborhood Hits	68	Shared Neighborhood Hits	9
SwissProt Accessions	Q9CR59, Q8BT05	Gene names	Gadd45gip1
Domain Architecture	No domain graphic available
Description	Growth arrest and DNA-damage-inducible proteins-interacting protein 1.

TRHY_HUMAN
θ value	0.47712 (rank : 9)	NC score	0.058967 (rank : 19)
Query Neighborhood Hits	85	Target Neighborhood Hits	1385	Shared Neighborhood Hits	50
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

XE7_HUMAN
θ value	0.62314 (rank : 10)	NC score	0.078501 (rank : 5)
Query Neighborhood Hits	85	Target Neighborhood Hits	738	Shared Neighborhood Hits	42
SwissProt Accessions	Q02040, Q02832	Gene names	CXYorf3, DXYS155E, XE7
Domain Architecture	No domain graphic available
Description	B-lymphocyte antigen precursor (B-lymphocyte surface antigen) (721P) (Protein XE7).

KIF3A_MOUSE
θ value	0.813845 (rank : 11)	NC score	0.041491 (rank : 57)
Query Neighborhood Hits	85	Target Neighborhood Hits	715	Shared Neighborhood Hits	47
SwissProt Accessions	P28741	Gene names	Kif3a, Kif3
Domain Architecture
Description	Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A).

MYPT1_HUMAN
θ value	1.06291 (rank : 12)	NC score	0.034426 (rank : 64)
Query Neighborhood Hits	85	Target Neighborhood Hits	723	Shared Neighborhood Hits	39
SwissProt Accessions	O14974, Q86WU3, Q8NFR6, Q9BYH0	Gene names	PPP1R12A, MBS, MYPT1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit).

SEM6B_HUMAN
θ value	1.06291 (rank : 13)	NC score	0.016307 (rank : 81)
Query Neighborhood Hits	85	Target Neighborhood Hits	187	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H3T3, Q9NRK9	Gene names	SEMA6B, SEMAZ
Domain Architecture
Description	Semaphorin-6B precursor (Semaphorin Z) (Sema Z).

BUB1B_MOUSE
θ value	1.81305 (rank : 14)	NC score	0.035568 (rank : 63)
Query Neighborhood Hits	85	Target Neighborhood Hits	202	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Z1S0	Gene names	Bub1b, Mad3l
Domain Architecture
Description	Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (EC 2.7.11.1) (MAD3/BUB1-related protein kinase) (Mitotic checkpoint kinase MAD3L).

CCD41_MOUSE
θ value	1.81305 (rank : 15)	NC score	0.057223 (rank : 21)
Query Neighborhood Hits	85	Target Neighborhood Hits	1399	Shared Neighborhood Hits	57
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

GOGA4_MOUSE
θ value	1.81305 (rank : 16)	NC score	0.057175 (rank : 22)
Query Neighborhood Hits	85	Target Neighborhood Hits	1939	Shared Neighborhood Hits	62
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

PEPL_HUMAN
θ value	1.81305 (rank : 17)	NC score	0.058705 (rank : 20)
Query Neighborhood Hits	85	Target Neighborhood Hits	1141	Shared Neighborhood Hits	53
SwissProt Accessions	O60437, O60314, O60454	Gene names	PPL, KIAA0568
Domain Architecture
Description	Periplakin (195 kDa cornified envelope precursor protein) (190 kDa paraneoplastic pemphigus antigen).

TBCD1_MOUSE
θ value	1.81305 (rank : 18)	NC score	0.039939 (rank : 60)
Query Neighborhood Hits	85	Target Neighborhood Hits	241	Shared Neighborhood Hits	21
SwissProt Accessions	Q60949, Q80TJ9, Q923F8	Gene names	Tbc1d1, Kiaa1108, Tbc1
Domain Architecture
Description	TBC1 domain family member 1.

CKAP4_HUMAN
θ value	2.36792 (rank : 19)	NC score	0.052137 (rank : 31)
Query Neighborhood Hits	85	Target Neighborhood Hits	592	Shared Neighborhood Hits	38
SwissProt Accessions	Q07065, Q504S5, Q53ES6	Gene names	CKAP4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

DESP_HUMAN
θ value	2.36792 (rank : 20)	NC score	0.054400 (rank : 26)
Query Neighborhood Hits	85	Target Neighborhood Hits	1470	Shared Neighborhood Hits	57
SwissProt Accessions	P15924, O75993, Q14189, Q9UHN4	Gene names	DSP
Domain Architecture
Description	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen).

DYNA_MOUSE
θ value	2.36792 (rank : 21)	NC score	0.049870 (rank : 40)
Query Neighborhood Hits	85	Target Neighborhood Hits	1084	Shared Neighborhood Hits	54
SwissProt Accessions	O08788	Gene names	Dctn1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued).

TMF1_HUMAN
θ value	2.36792 (rank : 22)	NC score	0.054395 (rank : 27)
Query Neighborhood Hits	85	Target Neighborhood Hits	987	Shared Neighborhood Hits	48
SwissProt Accessions	P82094	Gene names	TMF1
Domain Architecture	No domain graphic available
Description	TATA element modulatory factor (TMF).

AATF_HUMAN
θ value	3.0926 (rank : 23)	NC score	0.036859 (rank : 62)
Query Neighborhood Hits	85	Target Neighborhood Hits	38	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NY61, Q9P0A4, Q9UNX5	Gene names	AATF, CHE1, DED
Domain Architecture	No domain graphic available
Description	Protein AATF (Apoptosis-antagonizing transcription factor) (Rb-binding protein Che-1).

HOOK2_HUMAN
θ value	3.0926 (rank : 24)	NC score	0.063316 (rank : 11)
Query Neighborhood Hits	85	Target Neighborhood Hits	714	Shared Neighborhood Hits	50
SwissProt Accessions	Q96ED9, O60562	Gene names	HOOK2
Domain Architecture
Description	Hook homolog 2 (h-hook2) (hHK2).

JIP4_HUMAN
θ value	3.0926 (rank : 25)	NC score	0.043089 (rank : 55)
Query Neighborhood Hits	85	Target Neighborhood Hits	585	Shared Neighborhood Hits	36
SwissProt Accessions	O60271, O60905, Q3KQU8, Q3MKM7, Q86WC7, Q86WC8, Q8IZX7, Q96II0, Q9H811	Gene names	SPAG9, HSS, KIAA0516, MAPK8IP4, SYD1
Domain Architecture	No domain graphic available
Description	C-jun-amino-terminal kinase-interacting protein 4 (JNK-interacting protein 4) (JIP-4) (JNK-associated leucine-zipper protein) (JLP) (Sperm-associated antigen 9) (Mitogen-activated protein kinase 8- interacting protein 4) (Human lung cancer protein 6) (HLC-6) (Proliferation-inducing protein 6) (Sperm-specific protein) (Sperm surface protein) (Protein highly expressed in testis) (PHET) (Sunday driver 1).

JIP4_MOUSE
θ value	3.0926 (rank : 26)	NC score	0.040608 (rank : 59)
Query Neighborhood Hits	85	Target Neighborhood Hits	593	Shared Neighborhood Hits	32
SwissProt Accessions	Q58A65, Q3UH77, Q3UHF0, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2	Gene names	Spag9, Jip4, Jsap2, Kiaa0516, Mapk8ip4
Domain Architecture	No domain graphic available
Description	C-jun-amino-terminal kinase-interacting protein 4 (JNK-interacting protein 4) (JIP-4) (JNK-associated leucine-zipper protein) (JLP) (Sperm-associated antigen 9) (Mitogen-activated protein kinase 8- interacting protein 4) (JNK/SAPK-associated protein 2) (JSAP2).

MACF1_HUMAN
θ value	3.0926 (rank : 27)	NC score	0.045577 (rank : 49)
Query Neighborhood Hits	85	Target Neighborhood Hits	1341	Shared Neighborhood Hits	53
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

MACF4_HUMAN
θ value	3.0926 (rank : 28)	NC score	0.046783 (rank : 44)
Query Neighborhood Hits	85	Target Neighborhood Hits	1321	Shared Neighborhood Hits	55
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

MAK_MOUSE
θ value	3.0926 (rank : 29)	NC score	0.003751 (rank : 92)
Query Neighborhood Hits	85	Target Neighborhood Hits	873	Shared Neighborhood Hits	8
SwissProt Accessions	Q04859	Gene names	Mak, Rck
Domain Architecture
Description	Serine/threonine-protein kinase MAK (EC 2.7.11.22) (Male germ cell- associated kinase) (Protein kinase RCK).

MD1L1_HUMAN
θ value	3.0926 (rank : 30)	NC score	0.060945 (rank : 15)
Query Neighborhood Hits	85	Target Neighborhood Hits	893	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Y6D9, Q13312, Q75MI0, Q86UM4, Q9UNH0	Gene names	MAD1L1, MAD1, TXBP181
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1) (Mitotic checkpoint MAD1 protein-homolog) (HsMAD1) (hMAD1) (Tax-binding protein 181).

TNIK_HUMAN
θ value	3.0926 (rank : 31)	NC score	0.011956 (rank : 84)
Query Neighborhood Hits	85	Target Neighborhood Hits	1570	Shared Neighborhood Hits	41
SwissProt Accessions	Q9UKE5, O60298, Q8WUY7, Q9UKD8, Q9UKD9, Q9UKE0, Q9UKE1, Q9UKE2, Q9UKE3, Q9UKE4	Gene names	TNIK, KIAA0551
Domain Architecture
Description	TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1).

TRI37_HUMAN
θ value	3.0926 (rank : 32)	NC score	0.023260 (rank : 77)
Query Neighborhood Hits	85	Target Neighborhood Hits	307	Shared Neighborhood Hits	12
SwissProt Accessions	O94972, Q7Z3E6, Q8IYF7, Q8WYF7	Gene names	TRIM37, KIAA0898, MUL, POB1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37 (Mulibrey nanism protein).

UACA_MOUSE
θ value	3.0926 (rank : 33)	NC score	0.045719 (rank : 46)
Query Neighborhood Hits	85	Target Neighborhood Hits	1620	Shared Neighborhood Hits	52
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

UT14C_HUMAN
θ value	3.0926 (rank : 34)	NC score	0.045030 (rank : 50)
Query Neighborhood Hits	85	Target Neighborhood Hits	217	Shared Neighborhood Hits	25
SwissProt Accessions	Q5TAP6, Q5FWG3, Q92555	Gene names	UTP14C, KIAA0266
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 14 homolog C.

CAF1A_HUMAN
θ value	4.03905 (rank : 35)	NC score	0.069500 (rank : 8)
Query Neighborhood Hits	85	Target Neighborhood Hits	750	Shared Neighborhood Hits	44
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

ENL_HUMAN
θ value	4.03905 (rank : 36)	NC score	0.027626 (rank : 68)
Query Neighborhood Hits	85	Target Neighborhood Hits	305	Shared Neighborhood Hits	9
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

HOOK2_MOUSE
θ value	4.03905 (rank : 37)	NC score	0.060495 (rank : 16)
Query Neighborhood Hits	85	Target Neighborhood Hits	736	Shared Neighborhood Hits	49
SwissProt Accessions	Q7TMK6, Q8BY47, Q8R347, Q8VCN4, Q99LU2	Gene names	Hook2
Domain Architecture
Description	Hook homolog 2.

IF3A_MOUSE
θ value	4.03905 (rank : 38)	NC score	0.045648 (rank : 47)
Query Neighborhood Hits	85	Target Neighborhood Hits	871	Shared Neighborhood Hits	54
SwissProt Accessions	P23116, Q60697, Q62162	Gene names	Eif3s10, Csma, Eif3
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a) (p162 protein) (Centrosomin).

KIF3A_HUMAN
θ value	4.03905 (rank : 39)	NC score	0.037273 (rank : 61)
Query Neighborhood Hits	85	Target Neighborhood Hits	704	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Y496, Q86XE9, Q9Y6V4	Gene names	KIF3A, KIF3
Domain Architecture
Description	Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A).

LIPA2_HUMAN
θ value	4.03905 (rank : 40)	NC score	0.050357 (rank : 38)
Query Neighborhood Hits	85	Target Neighborhood Hits	1044	Shared Neighborhood Hits	53
SwissProt Accessions	O75334	Gene names	PPFIA2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

LRC45_HUMAN
θ value	4.03905 (rank : 41)	NC score	0.067601 (rank : 10)
Query Neighborhood Hits	85	Target Neighborhood Hits	933	Shared Neighborhood Hits	53
SwissProt Accessions	Q96CN5	Gene names	LRRC45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

LRC45_MOUSE
θ value	4.03905 (rank : 42)	NC score	0.061783 (rank : 12)
Query Neighborhood Hits	85	Target Neighborhood Hits	959	Shared Neighborhood Hits	55
SwissProt Accessions	Q8CIM1, Q3U5Z2	Gene names	Lrrc45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

RAI14_MOUSE
θ value	4.03905 (rank : 43)	NC score	0.041241 (rank : 58)
Query Neighborhood Hits	85	Target Neighborhood Hits	1505	Shared Neighborhood Hits	55
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

TPR_HUMAN
θ value	4.03905 (rank : 44)	NC score	0.050910 (rank : 36)
Query Neighborhood Hits	85	Target Neighborhood Hits	1921	Shared Neighborhood Hits	57
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

UBP34_HUMAN
θ value	4.03905 (rank : 45)	NC score	0.026379 (rank : 69)
Query Neighborhood Hits	85	Target Neighborhood Hits	210	Shared Neighborhood Hits	9
SwissProt Accessions	Q70CQ2, O60316, O94834, Q3B777, Q6P6C9, Q7L8P6, Q8N3T9, Q8TBW2, Q9UGA1	Gene names	USP34, KIAA0570, KIAA0729
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

UBP49_HUMAN
θ value	4.03905 (rank : 46)	NC score	0.023432 (rank : 75)
Query Neighborhood Hits	85	Target Neighborhood Hits	100	Shared Neighborhood Hits	5
SwissProt Accessions	Q70CQ1, Q96CK4	Gene names	USP49
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49).

BCL9_MOUSE
θ value	5.27518 (rank : 47)	NC score	0.022563 (rank : 78)
Query Neighborhood Hits	85	Target Neighborhood Hits	770	Shared Neighborhood Hits	11
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

DAB2P_HUMAN
θ value	5.27518 (rank : 48)	NC score	0.029314 (rank : 66)
Query Neighborhood Hits	85	Target Neighborhood Hits	303	Shared Neighborhood Hits	22
SwissProt Accessions	Q5VWQ8, Q8TDL2, Q96SE1, Q9C0C0	Gene names	DAB2IP, AF9Q34, AIP1, KIAA1743
Domain Architecture	No domain graphic available
Description	Disabled homolog 2-interacting protein (DAB2-interacting protein) (DAB2 interaction protein) (ASK-interacting protein 1).

DAB2P_MOUSE
θ value	5.27518 (rank : 49)	NC score	0.028876 (rank : 67)
Query Neighborhood Hits	85	Target Neighborhood Hits	284	Shared Neighborhood Hits	19
SwissProt Accessions	Q3UHC7, Q3TPD5, Q3UH44, Q6JTV1, Q80T97	Gene names	Dab2ip, Kiaa1743
Domain Architecture	No domain graphic available
Description	Disabled homolog 2-interacting protein (DAB2-interacting protein).

GRAP1_HUMAN
θ value	5.27518 (rank : 50)	NC score	0.045627 (rank : 48)
Query Neighborhood Hits	85	Target Neighborhood Hits	944	Shared Neighborhood Hits	50
SwissProt Accessions	Q4V328, Q4V327, Q4V330, Q5HYG1, Q6N046, Q96DH8, Q9NQ43, Q9ULQ3	Gene names	GRIPAP1, KIAA1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1).

HMMR_HUMAN
θ value	5.27518 (rank : 51)	NC score	0.049669 (rank : 41)
Query Neighborhood Hits	85	Target Neighborhood Hits	1082	Shared Neighborhood Hits	55
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

LIPA2_MOUSE
θ value	5.27518 (rank : 52)	NC score	0.051511 (rank : 33)
Query Neighborhood Hits	85	Target Neighborhood Hits	1282	Shared Neighborhood Hits	52
SwissProt Accessions	Q8BSS9, Q8BN73	Gene names	Ppfia2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

PARP2_HUMAN
θ value	5.27518 (rank : 53)	NC score	0.024840 (rank : 72)
Query Neighborhood Hits	85	Target Neighborhood Hits	33	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UGN5, Q8TEU4, Q9NUV2, Q9UMR4, Q9Y6C8	Gene names	PARP2, ADPRT2, ADPRTL2
Domain Architecture
Description	Poly [ADP-ribose] polymerase 2 (EC 2.4.2.30) (PARP-2) (NAD(+) ADP- ribosyltransferase 2) (Poly[ADP-ribose] synthetase 2) (pADPRT-2) (hPARP-2).

PEPL_MOUSE
θ value	5.27518 (rank : 54)	NC score	0.056655 (rank : 23)
Query Neighborhood Hits	85	Target Neighborhood Hits	1105	Shared Neighborhood Hits	55
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

RIMB1_MOUSE
θ value	5.27518 (rank : 55)	NC score	0.056346 (rank : 24)
Query Neighborhood Hits	85	Target Neighborhood Hits	1376	Shared Neighborhood Hits	56
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

RNF25_HUMAN
θ value	5.27518 (rank : 56)	NC score	0.023291 (rank : 76)
Query Neighborhood Hits	85	Target Neighborhood Hits	163	Shared Neighborhood Hits	4
SwissProt Accessions	Q96BH1, Q9H874	Gene names	RNF25
Domain Architecture
Description	RING finger protein 25 (EC 6.3.2.-).

RRBP1_MOUSE
θ value	5.27518 (rank : 57)	NC score	0.043370 (rank : 53)
Query Neighborhood Hits	85	Target Neighborhood Hits	1650	Shared Neighborhood Hits	58
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

SEPT8_MOUSE
θ value	5.27518 (rank : 58)	NC score	0.016565 (rank : 80)
Query Neighborhood Hits	85	Target Neighborhood Hits	251	Shared Neighborhood Hits	20
SwissProt Accessions	Q8CHH9, Q80YC7, Q9ESF7	Gene names	Sept8, Kiaa0202
Domain Architecture
Description	Septin-8.

UBP34_MOUSE
θ value	5.27518 (rank : 59)	NC score	0.025177 (rank : 70)
Query Neighborhood Hits	85	Target Neighborhood Hits	189	Shared Neighborhood Hits	7
SwissProt Accessions	Q6ZQ93, Q3UPN0, Q6P563, Q7TMJ6, Q8CCH0	Gene names	Usp34, Kiaa0570
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

FOXN1_MOUSE
θ value	6.88961 (rank : 60)	NC score	0.008736 (rank : 88)
Query Neighborhood Hits	85	Target Neighborhood Hits	300	Shared Neighborhood Hits	4
SwissProt Accessions	Q61575	Gene names	Foxn1, Fkh19, Hfh11, Whn
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude) (Hepatocyte nuclear factor 3 forkhead homolog 11) (HNF-3/forkhead homolog 11) (HFH-11).

GOGA4_HUMAN
θ value	6.88961 (rank : 61)	NC score	0.054044 (rank : 28)
Query Neighborhood Hits	85	Target Neighborhood Hits	2034	Shared Neighborhood Hits	61
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

INCE_MOUSE
θ value	6.88961 (rank : 62)	NC score	0.048094 (rank : 43)
Query Neighborhood Hits	85	Target Neighborhood Hits	903	Shared Neighborhood Hits	45
SwissProt Accessions	Q9WU62, Q7TN28, Q8BGN4, Q8CGI4	Gene names	Incenp
Domain Architecture
Description	Inner centromere protein.

MERL_MOUSE
θ value	6.88961 (rank : 63)	NC score	0.024989 (rank : 71)
Query Neighborhood Hits	85	Target Neighborhood Hits	524	Shared Neighborhood Hits	40
SwissProt Accessions	P46662, Q8BR03	Gene names	Nf2, Nf-2
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin).

PB1_HUMAN
θ value	6.88961 (rank : 64)	NC score	0.018183 (rank : 79)
Query Neighborhood Hits	85	Target Neighborhood Hits	261	Shared Neighborhood Hits	6
SwissProt Accessions	Q86U86, Q9H2T3, Q9H2T4, Q9H2T5, Q9H301, Q9H314	Gene names	PB1
Domain Architecture	No domain graphic available
Description	Protein polybromo-1 (hPB1) (Polybromo-1D) (BRG1-associated factor 180) (BAF180).

PLEC1_HUMAN
θ value	6.88961 (rank : 65)	NC score	0.044245 (rank : 52)
Query Neighborhood Hits	85	Target Neighborhood Hits	1326	Shared Neighborhood Hits	47
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

PRRT3_HUMAN
θ value	6.88961 (rank : 66)	NC score	0.014917 (rank : 82)
Query Neighborhood Hits	85	Target Neighborhood Hits	998	Shared Neighborhood Hits	15
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

SMCA2_HUMAN
θ value	6.88961 (rank : 67)	NC score	0.011106 (rank : 85)
Query Neighborhood Hits	85	Target Neighborhood Hits	503	Shared Neighborhood Hits	16
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

UACA_HUMAN
θ value	6.88961 (rank : 68)	NC score	0.041599 (rank : 56)
Query Neighborhood Hits	85	Target Neighborhood Hits	1622	Shared Neighborhood Hits	53
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

WDR67_HUMAN
θ value	6.88961 (rank : 69)	NC score	0.048953 (rank : 42)
Query Neighborhood Hits	85	Target Neighborhood Hits	782	Shared Neighborhood Hits	50
SwissProt Accessions	Q96DN5, Q3MIR6, Q8TBP9	Gene names	WDR67
Domain Architecture	No domain graphic available
Description	WD repeat protein 67.

AMOT_HUMAN
θ value	8.99809 (rank : 70)	NC score	0.043240 (rank : 54)
Query Neighborhood Hits	85	Target Neighborhood Hits	712	Shared Neighborhood Hits	36
SwissProt Accessions	Q4VCS5, Q504X5, Q9HD27, Q9UPT1	Gene names	AMOT, KIAA1071
Domain Architecture	No domain graphic available
Description	Angiomotin.

ARHGC_HUMAN
θ value	8.99809 (rank : 71)	NC score	0.008881 (rank : 87)
Query Neighborhood Hits	85	Target Neighborhood Hits	351	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

BCL9_HUMAN
θ value	8.99809 (rank : 72)	NC score	0.024774 (rank : 73)
Query Neighborhood Hits	85	Target Neighborhood Hits	1008	Shared Neighborhood Hits	13
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

CCHCR_MOUSE
θ value	8.99809 (rank : 73)	NC score	0.059096 (rank : 18)
Query Neighborhood Hits	85	Target Neighborhood Hits	932	Shared Neighborhood Hits	50
SwissProt Accessions	Q8K2I2	Gene names	Cchcr1, Hcr
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein).

CE290_HUMAN
θ value	8.99809 (rank : 74)	NC score	0.046517 (rank : 45)
Query Neighborhood Hits	85	Target Neighborhood Hits	1553	Shared Neighborhood Hits	55
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

CENPE_HUMAN
θ value	8.99809 (rank : 75)	NC score	0.044810 (rank : 51)
Query Neighborhood Hits	85	Target Neighborhood Hits	2060	Shared Neighborhood Hits	65
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

CREB3_HUMAN
θ value	8.99809 (rank : 76)	NC score	0.024435 (rank : 74)
Query Neighborhood Hits	85	Target Neighborhood Hits	138	Shared Neighborhood Hits	15
SwissProt Accessions	O43889, O14671, O14919, Q96GK8, Q9H2W3, Q9UE77	Gene names	CREB3, LZIP
Domain Architecture	No domain graphic available
Description	Cyclic AMP-responsive element-binding protein 3 (Luman protein) (Transcription factor LZIP-alpha).

IF4G1_HUMAN
θ value	8.99809 (rank : 77)	NC score	0.012545 (rank : 83)
Query Neighborhood Hits	85	Target Neighborhood Hits	347	Shared Neighborhood Hits	10
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

INCE_HUMAN
θ value	8.99809 (rank : 78)	NC score	0.052488 (rank : 30)
Query Neighborhood Hits	85	Target Neighborhood Hits	978	Shared Neighborhood Hits	50
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

NSD1_HUMAN
θ value	8.99809 (rank : 79)	NC score	0.009737 (rank : 86)
Query Neighborhood Hits	85	Target Neighborhood Hits	427	Shared Neighborhood Hits	5
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

OBSCN_HUMAN
θ value	8.99809 (rank : 80)	NC score	0.002890 (rank : 93)
Query Neighborhood Hits	85	Target Neighborhood Hits	1931	Shared Neighborhood Hits	12
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

PAX9_HUMAN
θ value	8.99809 (rank : 81)	NC score	0.008386 (rank : 89)
Query Neighborhood Hits	85	Target Neighborhood Hits	92	Shared Neighborhood Hits	3
SwissProt Accessions	P55771, Q99582, Q9UQR4	Gene names	PAX9
Domain Architecture
Description	Paired box protein Pax-9.

PLXB1_HUMAN
θ value	8.99809 (rank : 82)	NC score	0.008114 (rank : 90)
Query Neighborhood Hits	85	Target Neighborhood Hits	360	Shared Neighborhood Hits	9
SwissProt Accessions	O43157, Q6NY20, Q9UIV7, Q9UJ92, Q9UJ93	Gene names	PLXNB1, KIAA0407, SEP
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor (Semaphorin receptor SEP).

PRD16_HUMAN
θ value	8.99809 (rank : 83)	NC score	0.001523 (rank : 94)
Query Neighborhood Hits	85	Target Neighborhood Hits	832	Shared Neighborhood Hits	4
SwissProt Accessions	Q9HAZ2, Q8WYJ9, Q9C0I8	Gene names	PRDM16, KIAA1675, MEL1, PFM13
Domain Architecture
Description	PR domain zinc finger protein 16 (PR domain-containing protein 16) (Transcription factor MEL1).

TITIN_HUMAN
θ value	8.99809 (rank : 84)	NC score	0.006605 (rank : 91)
Query Neighborhood Hits	85	Target Neighborhood Hits	2923	Shared Neighborhood Hits	47
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

UT14B_MOUSE
θ value	8.99809 (rank : 85)	NC score	0.029651 (rank : 65)
Query Neighborhood Hits	85	Target Neighborhood Hits	226	Shared Neighborhood Hits	17
SwissProt Accessions	Q6EJB6, Q6EJB5, Q8BL60	Gene names	Utp14b, Jsd
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 14 homolog B (Juvenile spermatogonial depletion protein).

AKTS1_HUMAN
θ value	θ > 10 (rank : 86)	NC score	0.061202 (rank : 13)
Query Neighborhood Hits	85	Target Neighborhood Hits	40	Shared Neighborhood Hits	1
SwissProt Accessions	Q96B36, Q96BI4, Q96IK7, Q96NG2, Q9BWR5	Gene names	AKT1S1, PRAS40
Domain Architecture	No domain graphic available
Description	Proline-rich AKT1 substrate 1 (40 kDa proline-rich AKT substrate).

AMOL2_MOUSE
θ value	θ > 10 (rank : 87)	NC score	0.051420 (rank : 34)
Query Neighborhood Hits	85	Target Neighborhood Hits	591	Shared Neighborhood Hits	46
SwissProt Accessions	Q8K371, Q3TPM1, Q7TPE4, Q8BP84, Q8BS08, Q9QUS0	Gene names	Amotl2
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 2.

CCD46_MOUSE
θ value	θ > 10 (rank : 88)	NC score	0.050665 (rank : 37)
Query Neighborhood Hits	85	Target Neighborhood Hits	1405	Shared Neighborhood Hits	57
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

CP250_HUMAN
θ value	θ > 10 (rank : 89)	NC score	0.050321 (rank : 39)
Query Neighborhood Hits	85	Target Neighborhood Hits	1805	Shared Neighborhood Hits	61
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

MD1L1_MOUSE
θ value	θ > 10 (rank : 90)	NC score	0.053251 (rank : 29)
Query Neighborhood Hits	85	Target Neighborhood Hits	1001	Shared Neighborhood Hits	53
SwissProt Accessions	Q9WTX8, Q9WTX9	Gene names	Mad1l1, Mad1
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1).

RABX5_HUMAN
θ value	θ > 10 (rank : 91)	NC score	0.051304 (rank : 35)
Query Neighborhood Hits	85	Target Neighborhood Hits	68	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UJ41	Gene names	RABGEF1, RABEX5
Domain Architecture
Description	Rab5 GDP/GTP exchange factor (Rabex-5) (Rabaptin-5-associated exchange factor for Rab5).

RABX5_MOUSE
θ value	θ > 10 (rank : 92)	NC score	0.061199 (rank : 14)
Query Neighborhood Hits	85	Target Neighborhood Hits	39	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JM13, Q3UIW0	Gene names	Rabgef1, Rabex5
Domain Architecture
Description	Rab5 GDP/GTP exchange factor (Rabex-5).

RIN1_HUMAN
θ value	θ > 10 (rank : 93)	NC score	0.051542 (rank : 32)
Query Neighborhood Hits	85	Target Neighborhood Hits	52	Shared Neighborhood Hits	1
SwissProt Accessions	Q13671, O15010, Q00427, Q96CC8	Gene names	RIN1
Domain Architecture
Description	Ras and Rab interactor 1 (Ras interaction/interference protein 1) (Ras inhibitor JC99).

RIN1_MOUSE
θ value	θ > 10 (rank : 94)	NC score	0.055948 (rank : 25)
Query Neighborhood Hits	85	Target Neighborhood Hits	45	Shared Neighborhood Hits	1
SwissProt Accessions	Q921Q7	Gene names	Rin1
Domain Architecture
Description	Ras and Rab interactor 1 (Ras interaction/interference protein 1).

Hits sorted by NC score

CP007_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	85	Target Neighborhood Hits	85	Shared Neighborhood Hits	85
SwissProt Accessions	Q9Y2B5	Gene names	C16orf7, ATPBL
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf7 (Protein ATP-BL).

CP007_MOUSE
NC score	0.862119 (rank : 2)	θ value	1.20704e-137 (rank : 2)
Query Neighborhood Hits	85	Target Neighborhood Hits	231	Shared Neighborhood Hits	34
SwissProt Accessions	Q8C190, Q6PFD1	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C16orf7 homolog (5-day ovary-specific transcript 1 protein).

G45IP_MOUSE
NC score	0.100759 (rank : 3)	θ value	0.47712 (rank : 8)
Query Neighborhood Hits	85	Target Neighborhood Hits	68	Shared Neighborhood Hits	9
SwissProt Accessions	Q9CR59, Q8BT05	Gene names	Gadd45gip1
Domain Architecture	No domain graphic available
Description	Growth arrest and DNA-damage-inducible proteins-interacting protein 1.

AMOL2_HUMAN
NC score	0.081957 (rank : 4)	θ value	0.47712 (rank : 6)
Query Neighborhood Hits	85	Target Neighborhood Hits	603	Shared Neighborhood Hits	50
SwissProt Accessions	Q9Y2J4, Q53EP1, Q96F99, Q9UKB4	Gene names	AMOTL2, KIAA0989
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 2 (Leman coiled-coil protein) (LCCP).

XE7_HUMAN
NC score	0.078501 (rank : 5)	θ value	0.62314 (rank : 10)
Query Neighborhood Hits	85	Target Neighborhood Hits	738	Shared Neighborhood Hits	42
SwissProt Accessions	Q02040, Q02832	Gene names	CXYorf3, DXYS155E, XE7
Domain Architecture	No domain graphic available
Description	B-lymphocyte antigen precursor (B-lymphocyte surface antigen) (721P) (Protein XE7).

CF182_MOUSE
NC score	0.074919 (rank : 6)	θ value	0.279714 (rank : 3)
Query Neighborhood Hits	85	Target Neighborhood Hits	551	Shared Neighborhood Hits	43
SwissProt Accessions	Q8VDS7, Q9CZE0, Q9D5A1	Gene names
Domain Architecture	No domain graphic available
Description	Protein C6orf182 homolog.

CAF1A_MOUSE
NC score	0.071636 (rank : 7)	θ value	0.47712 (rank : 7)
Query Neighborhood Hits	85	Target Neighborhood Hits	736	Shared Neighborhood Hits	38
SwissProt Accessions	Q9QWF0	Gene names	Chaf1a, Caip150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

CAF1A_HUMAN
NC score	0.069500 (rank : 8)	θ value	4.03905 (rank : 35)
Query Neighborhood Hits	85	Target Neighborhood Hits	750	Shared Neighborhood Hits	44
SwissProt Accessions	Q13111, Q7Z7K3, Q9UJY8	Gene names	CHAF1A, CAF, CAF1P150
Domain Architecture	No domain graphic available
Description	Chromatin assembly factor 1 subunit A (CAF-1 subunit A) (Chromatin assembly factor I p150 subunit) (CAF-I 150 kDa subunit) (CAF-Ip150).

CCHCR_HUMAN
NC score	0.068960 (rank : 9)	θ value	0.365318 (rank : 5)
Query Neighborhood Hits	85	Target Neighborhood Hits	717	Shared Neighborhood Hits	45
SwissProt Accessions	Q8TD31, Q9NRK8, Q9NWY9, Q9NXJ4, Q9NXK3, Q9Y6W1, Q9Y6W2	Gene names	CCHCR1, C6orf18, HCR
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein) (Putative gene 8 protein) (Pg8).

LRC45_HUMAN
NC score	0.067601 (rank : 10)	θ value	4.03905 (rank : 41)
Query Neighborhood Hits	85	Target Neighborhood Hits	933	Shared Neighborhood Hits	53
SwissProt Accessions	Q96CN5	Gene names	LRRC45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

HOOK2_HUMAN
NC score	0.063316 (rank : 11)	θ value	3.0926 (rank : 24)
Query Neighborhood Hits	85	Target Neighborhood Hits	714	Shared Neighborhood Hits	50
SwissProt Accessions	Q96ED9, O60562	Gene names	HOOK2
Domain Architecture
Description	Hook homolog 2 (h-hook2) (hHK2).

LRC45_MOUSE
NC score	0.061783 (rank : 12)	θ value	4.03905 (rank : 42)
Query Neighborhood Hits	85	Target Neighborhood Hits	959	Shared Neighborhood Hits	55
SwissProt Accessions	Q8CIM1, Q3U5Z2	Gene names	Lrrc45
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 45.

AKTS1_HUMAN
NC score	0.061202 (rank : 13)	θ value	θ > 10 (rank : 86)
Query Neighborhood Hits	85	Target Neighborhood Hits	40	Shared Neighborhood Hits	1
SwissProt Accessions	Q96B36, Q96BI4, Q96IK7, Q96NG2, Q9BWR5	Gene names	AKT1S1, PRAS40
Domain Architecture	No domain graphic available
Description	Proline-rich AKT1 substrate 1 (40 kDa proline-rich AKT substrate).

RABX5_MOUSE
NC score	0.061199 (rank : 14)	θ value	θ > 10 (rank : 92)
Query Neighborhood Hits	85	Target Neighborhood Hits	39	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JM13, Q3UIW0	Gene names	Rabgef1, Rabex5
Domain Architecture
Description	Rab5 GDP/GTP exchange factor (Rabex-5).

MD1L1_HUMAN
NC score	0.060945 (rank : 15)	θ value	3.0926 (rank : 30)
Query Neighborhood Hits	85	Target Neighborhood Hits	893	Shared Neighborhood Hits	51
SwissProt Accessions	Q9Y6D9, Q13312, Q75MI0, Q86UM4, Q9UNH0	Gene names	MAD1L1, MAD1, TXBP181
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1) (Mitotic checkpoint MAD1 protein-homolog) (HsMAD1) (hMAD1) (Tax-binding protein 181).

HOOK2_MOUSE
NC score	0.060495 (rank : 16)	θ value	4.03905 (rank : 37)
Query Neighborhood Hits	85	Target Neighborhood Hits	736	Shared Neighborhood Hits	49
SwissProt Accessions	Q7TMK6, Q8BY47, Q8R347, Q8VCN4, Q99LU2	Gene names	Hook2
Domain Architecture
Description	Hook homolog 2.

IL4RA_MOUSE
NC score	0.060377 (rank : 17)	θ value	0.279714 (rank : 4)
Query Neighborhood Hits	85	Target Neighborhood Hits	194	Shared Neighborhood Hits	4
SwissProt Accessions	P16382, O54690, Q60583, Q8CBW5	Gene names	Il4r, Il4ra
Domain Architecture
Description	Interleukin-4 receptor alpha chain precursor (IL-4R-alpha) (CD124 antigen) [Contains: Soluble interleukin-4 receptor alpha chain (IL-4- binding protein) (IL4-BP)].

CCHCR_MOUSE
NC score	0.059096 (rank : 18)	θ value	8.99809 (rank : 73)
Query Neighborhood Hits	85	Target Neighborhood Hits	932	Shared Neighborhood Hits	50
SwissProt Accessions	Q8K2I2	Gene names	Cchcr1, Hcr
Domain Architecture
Description	Coiled-coil alpha-helical rod protein 1 (Alpha helical coiled-coil rod protein).

TRHY_HUMAN
NC score	0.058967 (rank : 19)	θ value	0.47712 (rank : 9)
Query Neighborhood Hits	85	Target Neighborhood Hits	1385	Shared Neighborhood Hits	50
SwissProt Accessions	Q07283	Gene names	THH, THL, TRHY
Domain Architecture
Description	Trichohyalin.

PEPL_HUMAN
NC score	0.058705 (rank : 20)	θ value	1.81305 (rank : 17)
Query Neighborhood Hits	85	Target Neighborhood Hits	1141	Shared Neighborhood Hits	53
SwissProt Accessions	O60437, O60314, O60454	Gene names	PPL, KIAA0568
Domain Architecture
Description	Periplakin (195 kDa cornified envelope precursor protein) (190 kDa paraneoplastic pemphigus antigen).

CCD41_MOUSE
NC score	0.057223 (rank : 21)	θ value	1.81305 (rank : 15)
Query Neighborhood Hits	85	Target Neighborhood Hits	1399	Shared Neighborhood Hits	57
SwissProt Accessions	Q9D5R3, Q3U7X7, Q3UX57, Q80VF0	Gene names	Ccdc41
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 41.

GOGA4_MOUSE
NC score	0.057175 (rank : 22)	θ value	1.81305 (rank : 16)
Query Neighborhood Hits	85	Target Neighborhood Hits	1939	Shared Neighborhood Hits	62
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

PEPL_MOUSE
NC score	0.056655 (rank : 23)	θ value	5.27518 (rank : 54)
Query Neighborhood Hits	85	Target Neighborhood Hits	1105	Shared Neighborhood Hits	55
SwissProt Accessions	Q9R269, O70231, Q9CUT1, Q9JLZ7	Gene names	Ppl
Domain Architecture
Description	Periplakin.

RIMB1_MOUSE
NC score	0.056346 (rank : 24)	θ value	5.27518 (rank : 55)
Query Neighborhood Hits	85	Target Neighborhood Hits	1376	Shared Neighborhood Hits	56
SwissProt Accessions	Q7TNF8, Q5NCP7, Q80TV9, Q8BIH5	Gene names	Bzrap1, Kiaa0612, Rbp1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

RIN1_MOUSE
NC score	0.055948 (rank : 25)	θ value	θ > 10 (rank : 94)
Query Neighborhood Hits	85	Target Neighborhood Hits	45	Shared Neighborhood Hits	1
SwissProt Accessions	Q921Q7	Gene names	Rin1
Domain Architecture
Description	Ras and Rab interactor 1 (Ras interaction/interference protein 1).

DESP_HUMAN
NC score	0.054400 (rank : 26)	θ value	2.36792 (rank : 20)
Query Neighborhood Hits	85	Target Neighborhood Hits	1470	Shared Neighborhood Hits	57
SwissProt Accessions	P15924, O75993, Q14189, Q9UHN4	Gene names	DSP
Domain Architecture
Description	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen).

TMF1_HUMAN
NC score	0.054395 (rank : 27)	θ value	2.36792 (rank : 22)
Query Neighborhood Hits	85	Target Neighborhood Hits	987	Shared Neighborhood Hits	48
SwissProt Accessions	P82094	Gene names	TMF1
Domain Architecture	No domain graphic available
Description	TATA element modulatory factor (TMF).

GOGA4_HUMAN
NC score	0.054044 (rank : 28)	θ value	6.88961 (rank : 61)
Query Neighborhood Hits	85	Target Neighborhood Hits	2034	Shared Neighborhood Hits	61
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

MD1L1_MOUSE
NC score	0.053251 (rank : 29)	θ value	θ > 10 (rank : 90)
Query Neighborhood Hits	85	Target Neighborhood Hits	1001	Shared Neighborhood Hits	53
SwissProt Accessions	Q9WTX8, Q9WTX9	Gene names	Mad1l1, Mad1
Domain Architecture	No domain graphic available
Description	Mitotic spindle assembly checkpoint protein MAD1 (Mitotic arrest deficient-like protein 1) (MAD1-like 1).

INCE_HUMAN
NC score	0.052488 (rank : 30)	θ value	8.99809 (rank : 78)
Query Neighborhood Hits	85	Target Neighborhood Hits	978	Shared Neighborhood Hits	50
SwissProt Accessions	Q9NQS7, Q5Y192	Gene names	INCENP
Domain Architecture
Description	Inner centromere protein.

CKAP4_HUMAN
NC score	0.052137 (rank : 31)	θ value	2.36792 (rank : 19)
Query Neighborhood Hits	85	Target Neighborhood Hits	592	Shared Neighborhood Hits	38
SwissProt Accessions	Q07065, Q504S5, Q53ES6	Gene names	CKAP4
Domain Architecture	No domain graphic available
Description	Cytoskeleton-associated protein 4 (63 kDa membrane protein) (p63).

RIN1_HUMAN
NC score	0.051542 (rank : 32)	θ value	θ > 10 (rank : 93)
Query Neighborhood Hits	85	Target Neighborhood Hits	52	Shared Neighborhood Hits	1
SwissProt Accessions	Q13671, O15010, Q00427, Q96CC8	Gene names	RIN1
Domain Architecture
Description	Ras and Rab interactor 1 (Ras interaction/interference protein 1) (Ras inhibitor JC99).

LIPA2_MOUSE
NC score	0.051511 (rank : 33)	θ value	5.27518 (rank : 52)
Query Neighborhood Hits	85	Target Neighborhood Hits	1282	Shared Neighborhood Hits	52
SwissProt Accessions	Q8BSS9, Q8BN73	Gene names	Ppfia2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

AMOL2_MOUSE
NC score	0.051420 (rank : 34)	θ value	θ > 10 (rank : 87)
Query Neighborhood Hits	85	Target Neighborhood Hits	591	Shared Neighborhood Hits	46
SwissProt Accessions	Q8K371, Q3TPM1, Q7TPE4, Q8BP84, Q8BS08, Q9QUS0	Gene names	Amotl2
Domain Architecture	No domain graphic available
Description	Angiomotin-like protein 2.

RABX5_HUMAN
NC score	0.051304 (rank : 35)	θ value	θ > 10 (rank : 91)
Query Neighborhood Hits	85	Target Neighborhood Hits	68	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UJ41	Gene names	RABGEF1, RABEX5
Domain Architecture
Description	Rab5 GDP/GTP exchange factor (Rabex-5) (Rabaptin-5-associated exchange factor for Rab5).

TPR_HUMAN
NC score	0.050910 (rank : 36)	θ value	4.03905 (rank : 44)
Query Neighborhood Hits	85	Target Neighborhood Hits	1921	Shared Neighborhood Hits	57
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

CCD46_MOUSE
NC score	0.050665 (rank : 37)	θ value	θ > 10 (rank : 88)
Query Neighborhood Hits	85	Target Neighborhood Hits	1405	Shared Neighborhood Hits	57
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

LIPA2_HUMAN
NC score	0.050357 (rank : 38)	θ value	4.03905 (rank : 40)
Query Neighborhood Hits	85	Target Neighborhood Hits	1044	Shared Neighborhood Hits	53
SwissProt Accessions	O75334	Gene names	PPFIA2
Domain Architecture
Description	Liprin-alpha-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2) (PTPRF-interacting protein alpha-2).

CP250_HUMAN
NC score	0.050321 (rank : 39)	θ value	θ > 10 (rank : 89)
Query Neighborhood Hits	85	Target Neighborhood Hits	1805	Shared Neighborhood Hits	61
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

DYNA_MOUSE
NC score	0.049870 (rank : 40)	θ value	2.36792 (rank : 21)
Query Neighborhood Hits	85	Target Neighborhood Hits	1084	Shared Neighborhood Hits	54
SwissProt Accessions	O08788	Gene names	Dctn1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued).

HMMR_HUMAN
NC score	0.049669 (rank : 41)	θ value	5.27518 (rank : 51)
Query Neighborhood Hits	85	Target Neighborhood Hits	1082	Shared Neighborhood Hits	55
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

WDR67_HUMAN
NC score	0.048953 (rank : 42)	θ value	6.88961 (rank : 69)
Query Neighborhood Hits	85	Target Neighborhood Hits	782	Shared Neighborhood Hits	50
SwissProt Accessions	Q96DN5, Q3MIR6, Q8TBP9	Gene names	WDR67
Domain Architecture	No domain graphic available
Description	WD repeat protein 67.

INCE_MOUSE
NC score	0.048094 (rank : 43)	θ value	6.88961 (rank : 62)
Query Neighborhood Hits	85	Target Neighborhood Hits	903	Shared Neighborhood Hits	45
SwissProt Accessions	Q9WU62, Q7TN28, Q8BGN4, Q8CGI4	Gene names	Incenp
Domain Architecture
Description	Inner centromere protein.

MACF4_HUMAN
NC score	0.046783 (rank : 44)	θ value	3.0926 (rank : 28)
Query Neighborhood Hits	85	Target Neighborhood Hits	1321	Shared Neighborhood Hits	55
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

CE290_HUMAN
NC score	0.046517 (rank : 45)	θ value	8.99809 (rank : 74)
Query Neighborhood Hits	85	Target Neighborhood Hits	1553	Shared Neighborhood Hits	55
SwissProt Accessions	O15078, Q1PSK5, Q66GS8, Q9H2G6, Q9H6Q7, Q9H8I0	Gene names	CEP290, KIAA0373, NPHP6
Domain Architecture	No domain graphic available
Description	Centrosomal protein Cep290 (Nephrocystin-6) (Tumor antigen se2-2).

UACA_MOUSE
NC score	0.045719 (rank : 46)	θ value	3.0926 (rank : 33)
Query Neighborhood Hits	85	Target Neighborhood Hits	1620	Shared Neighborhood Hits	52
SwissProt Accessions	Q8CGB3, Q69ZG3, Q7TN77, Q8BJC8	Gene names	Uaca, Kiaa1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein (Nucling) (Nuclear membrane-binding protein).

IF3A_MOUSE
NC score	0.045648 (rank : 47)	θ value	4.03905 (rank : 38)
Query Neighborhood Hits	85	Target Neighborhood Hits	871	Shared Neighborhood Hits	54
SwissProt Accessions	P23116, Q60697, Q62162	Gene names	Eif3s10, Csma, Eif3
Domain Architecture
Description	Eukaryotic translation initiation factor 3 subunit 10 (eIF-3 theta) (eIF3 p167) (eIF3 p180) (eIF3 p185) (eIF3a) (p162 protein) (Centrosomin).

GRAP1_HUMAN
NC score	0.045627 (rank : 48)	θ value	5.27518 (rank : 50)
Query Neighborhood Hits	85	Target Neighborhood Hits	944	Shared Neighborhood Hits	50
SwissProt Accessions	Q4V328, Q4V327, Q4V330, Q5HYG1, Q6N046, Q96DH8, Q9NQ43, Q9ULQ3	Gene names	GRIPAP1, KIAA1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1).

MACF1_HUMAN
NC score	0.045577 (rank : 49)	θ value	3.0926 (rank : 27)
Query Neighborhood Hits	85	Target Neighborhood Hits	1341	Shared Neighborhood Hits	53
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

UT14C_HUMAN
NC score	0.045030 (rank : 50)	θ value	3.0926 (rank : 34)
Query Neighborhood Hits	85	Target Neighborhood Hits	217	Shared Neighborhood Hits	25
SwissProt Accessions	Q5TAP6, Q5FWG3, Q92555	Gene names	UTP14C, KIAA0266
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 14 homolog C.

CENPE_HUMAN
NC score	0.044810 (rank : 51)	θ value	8.99809 (rank : 75)
Query Neighborhood Hits	85	Target Neighborhood Hits	2060	Shared Neighborhood Hits	65
SwissProt Accessions	Q02224	Gene names	CENPE
Domain Architecture
Description	Centromeric protein E (CENP-E).

PLEC1_HUMAN
NC score	0.044245 (rank : 52)	θ value	6.88961 (rank : 65)
Query Neighborhood Hits	85	Target Neighborhood Hits	1326	Shared Neighborhood Hits	47
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

RRBP1_MOUSE
NC score	0.043370 (rank : 53)	θ value	5.27518 (rank : 57)
Query Neighborhood Hits	85	Target Neighborhood Hits	1650	Shared Neighborhood Hits	58
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

AMOT_HUMAN
NC score	0.043240 (rank : 54)	θ value	8.99809 (rank : 70)
Query Neighborhood Hits	85	Target Neighborhood Hits	712	Shared Neighborhood Hits	36
SwissProt Accessions	Q4VCS5, Q504X5, Q9HD27, Q9UPT1	Gene names	AMOT, KIAA1071
Domain Architecture	No domain graphic available
Description	Angiomotin.

JIP4_HUMAN
NC score	0.043089 (rank : 55)	θ value	3.0926 (rank : 25)
Query Neighborhood Hits	85	Target Neighborhood Hits	585	Shared Neighborhood Hits	36
SwissProt Accessions	O60271, O60905, Q3KQU8, Q3MKM7, Q86WC7, Q86WC8, Q8IZX7, Q96II0, Q9H811	Gene names	SPAG9, HSS, KIAA0516, MAPK8IP4, SYD1
Domain Architecture	No domain graphic available
Description	C-jun-amino-terminal kinase-interacting protein 4 (JNK-interacting protein 4) (JIP-4) (JNK-associated leucine-zipper protein) (JLP) (Sperm-associated antigen 9) (Mitogen-activated protein kinase 8- interacting protein 4) (Human lung cancer protein 6) (HLC-6) (Proliferation-inducing protein 6) (Sperm-specific protein) (Sperm surface protein) (Protein highly expressed in testis) (PHET) (Sunday driver 1).

UACA_HUMAN
NC score	0.041599 (rank : 56)	θ value	6.88961 (rank : 68)
Query Neighborhood Hits	85	Target Neighborhood Hits	1622	Shared Neighborhood Hits	53
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

KIF3A_MOUSE
NC score	0.041491 (rank : 57)	θ value	0.813845 (rank : 11)
Query Neighborhood Hits	85	Target Neighborhood Hits	715	Shared Neighborhood Hits	47
SwissProt Accessions	P28741	Gene names	Kif3a, Kif3
Domain Architecture
Description	Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A).

RAI14_MOUSE
NC score	0.041241 (rank : 58)	θ value	4.03905 (rank : 43)
Query Neighborhood Hits	85	Target Neighborhood Hits	1505	Shared Neighborhood Hits	55
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

JIP4_MOUSE
NC score	0.040608 (rank : 59)	θ value	3.0926 (rank : 26)
Query Neighborhood Hits	85	Target Neighborhood Hits	593	Shared Neighborhood Hits	32
SwissProt Accessions	Q58A65, Q3UH77, Q3UHF0, Q58VQ4, Q5NC70, Q5NC78, Q6A057, Q6PAS3, Q8CJC2	Gene names	Spag9, Jip4, Jsap2, Kiaa0516, Mapk8ip4
Domain Architecture	No domain graphic available
Description	C-jun-amino-terminal kinase-interacting protein 4 (JNK-interacting protein 4) (JIP-4) (JNK-associated leucine-zipper protein) (JLP) (Sperm-associated antigen 9) (Mitogen-activated protein kinase 8- interacting protein 4) (JNK/SAPK-associated protein 2) (JSAP2).

TBCD1_MOUSE
NC score	0.039939 (rank : 60)	θ value	1.81305 (rank : 18)
Query Neighborhood Hits	85	Target Neighborhood Hits	241	Shared Neighborhood Hits	21
SwissProt Accessions	Q60949, Q80TJ9, Q923F8	Gene names	Tbc1d1, Kiaa1108, Tbc1
Domain Architecture
Description	TBC1 domain family member 1.

KIF3A_HUMAN
NC score	0.037273 (rank : 61)	θ value	4.03905 (rank : 39)
Query Neighborhood Hits	85	Target Neighborhood Hits	704	Shared Neighborhood Hits	45
SwissProt Accessions	Q9Y496, Q86XE9, Q9Y6V4	Gene names	KIF3A, KIF3
Domain Architecture
Description	Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A).

AATF_HUMAN
NC score	0.036859 (rank : 62)	θ value	3.0926 (rank : 23)
Query Neighborhood Hits	85	Target Neighborhood Hits	38	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NY61, Q9P0A4, Q9UNX5	Gene names	AATF, CHE1, DED
Domain Architecture	No domain graphic available
Description	Protein AATF (Apoptosis-antagonizing transcription factor) (Rb-binding protein Che-1).

BUB1B_MOUSE
NC score	0.035568 (rank : 63)	θ value	1.81305 (rank : 14)
Query Neighborhood Hits	85	Target Neighborhood Hits	202	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Z1S0	Gene names	Bub1b, Mad3l
Domain Architecture
Description	Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (EC 2.7.11.1) (MAD3/BUB1-related protein kinase) (Mitotic checkpoint kinase MAD3L).

MYPT1_HUMAN
NC score	0.034426 (rank : 64)	θ value	1.06291 (rank : 12)
Query Neighborhood Hits	85	Target Neighborhood Hits	723	Shared Neighborhood Hits	39
SwissProt Accessions	O14974, Q86WU3, Q8NFR6, Q9BYH0	Gene names	PPP1R12A, MBS, MYPT1
Domain Architecture
Description	Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase- targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit).

UT14B_MOUSE
NC score	0.029651 (rank : 65)	θ value	8.99809 (rank : 85)
Query Neighborhood Hits	85	Target Neighborhood Hits	226	Shared Neighborhood Hits	17
SwissProt Accessions	Q6EJB6, Q6EJB5, Q8BL60	Gene names	Utp14b, Jsd
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 14 homolog B (Juvenile spermatogonial depletion protein).

DAB2P_HUMAN
NC score	0.029314 (rank : 66)	θ value	5.27518 (rank : 48)
Query Neighborhood Hits	85	Target Neighborhood Hits	303	Shared Neighborhood Hits	22
SwissProt Accessions	Q5VWQ8, Q8TDL2, Q96SE1, Q9C0C0	Gene names	DAB2IP, AF9Q34, AIP1, KIAA1743
Domain Architecture	No domain graphic available
Description	Disabled homolog 2-interacting protein (DAB2-interacting protein) (DAB2 interaction protein) (ASK-interacting protein 1).

DAB2P_MOUSE
NC score	0.028876 (rank : 67)	θ value	5.27518 (rank : 49)
Query Neighborhood Hits	85	Target Neighborhood Hits	284	Shared Neighborhood Hits	19
SwissProt Accessions	Q3UHC7, Q3TPD5, Q3UH44, Q6JTV1, Q80T97	Gene names	Dab2ip, Kiaa1743
Domain Architecture	No domain graphic available
Description	Disabled homolog 2-interacting protein (DAB2-interacting protein).

ENL_HUMAN
NC score	0.027626 (rank : 68)	θ value	4.03905 (rank : 36)
Query Neighborhood Hits	85	Target Neighborhood Hits	305	Shared Neighborhood Hits	9
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

UBP34_HUMAN
NC score	0.026379 (rank : 69)	θ value	4.03905 (rank : 45)
Query Neighborhood Hits	85	Target Neighborhood Hits	210	Shared Neighborhood Hits	9
SwissProt Accessions	Q70CQ2, O60316, O94834, Q3B777, Q6P6C9, Q7L8P6, Q8N3T9, Q8TBW2, Q9UGA1	Gene names	USP34, KIAA0570, KIAA0729
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

UBP34_MOUSE
NC score	0.025177 (rank : 70)	θ value	5.27518 (rank : 59)
Query Neighborhood Hits	85	Target Neighborhood Hits	189	Shared Neighborhood Hits	7
SwissProt Accessions	Q6ZQ93, Q3UPN0, Q6P563, Q7TMJ6, Q8CCH0	Gene names	Usp34, Kiaa0570
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.1.2.15) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) (Deubiquitinating enzyme 34).

MERL_MOUSE
NC score	0.024989 (rank : 71)	θ value	6.88961 (rank : 63)
Query Neighborhood Hits	85	Target Neighborhood Hits	524	Shared Neighborhood Hits	40
SwissProt Accessions	P46662, Q8BR03	Gene names	Nf2, Nf-2
Domain Architecture
Description	Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin).

PARP2_HUMAN
NC score	0.024840 (rank : 72)	θ value	5.27518 (rank : 53)
Query Neighborhood Hits	85	Target Neighborhood Hits	33	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UGN5, Q8TEU4, Q9NUV2, Q9UMR4, Q9Y6C8	Gene names	PARP2, ADPRT2, ADPRTL2
Domain Architecture
Description	Poly [ADP-ribose] polymerase 2 (EC 2.4.2.30) (PARP-2) (NAD(+) ADP- ribosyltransferase 2) (Poly[ADP-ribose] synthetase 2) (pADPRT-2) (hPARP-2).

BCL9_HUMAN
NC score	0.024774 (rank : 73)	θ value	8.99809 (rank : 72)
Query Neighborhood Hits	85	Target Neighborhood Hits	1008	Shared Neighborhood Hits	13
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

CREB3_HUMAN
NC score	0.024435 (rank : 74)	θ value	8.99809 (rank : 76)
Query Neighborhood Hits	85	Target Neighborhood Hits	138	Shared Neighborhood Hits	15
SwissProt Accessions	O43889, O14671, O14919, Q96GK8, Q9H2W3, Q9UE77	Gene names	CREB3, LZIP
Domain Architecture	No domain graphic available
Description	Cyclic AMP-responsive element-binding protein 3 (Luman protein) (Transcription factor LZIP-alpha).

UBP49_HUMAN
NC score	0.023432 (rank : 75)	θ value	4.03905 (rank : 46)
Query Neighborhood Hits	85	Target Neighborhood Hits	100	Shared Neighborhood Hits	5
SwissProt Accessions	Q70CQ1, Q96CK4	Gene names	USP49
Domain Architecture	No domain graphic available
Description	Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.1.2.15) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49) (Deubiquitinating enzyme 49).

RNF25_HUMAN
NC score	0.023291 (rank : 76)	θ value	5.27518 (rank : 56)
Query Neighborhood Hits	85	Target Neighborhood Hits	163	Shared Neighborhood Hits	4
SwissProt Accessions	Q96BH1, Q9H874	Gene names	RNF25
Domain Architecture
Description	RING finger protein 25 (EC 6.3.2.-).

TRI37_HUMAN
NC score	0.023260 (rank : 77)	θ value	3.0926 (rank : 32)
Query Neighborhood Hits	85	Target Neighborhood Hits	307	Shared Neighborhood Hits	12
SwissProt Accessions	O94972, Q7Z3E6, Q8IYF7, Q8WYF7	Gene names	TRIM37, KIAA0898, MUL, POB1
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 37 (Mulibrey nanism protein).

BCL9_MOUSE
NC score	0.022563 (rank : 78)	θ value	5.27518 (rank : 47)
Query Neighborhood Hits	85	Target Neighborhood Hits	770	Shared Neighborhood Hits	11
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

PB1_HUMAN
NC score	0.018183 (rank : 79)	θ value	6.88961 (rank : 64)
Query Neighborhood Hits	85	Target Neighborhood Hits	261	Shared Neighborhood Hits	6
SwissProt Accessions	Q86U86, Q9H2T3, Q9H2T4, Q9H2T5, Q9H301, Q9H314	Gene names	PB1
Domain Architecture	No domain graphic available
Description	Protein polybromo-1 (hPB1) (Polybromo-1D) (BRG1-associated factor 180) (BAF180).

SEPT8_MOUSE
NC score	0.016565 (rank : 80)	θ value	5.27518 (rank : 58)
Query Neighborhood Hits	85	Target Neighborhood Hits	251	Shared Neighborhood Hits	20
SwissProt Accessions	Q8CHH9, Q80YC7, Q9ESF7	Gene names	Sept8, Kiaa0202
Domain Architecture
Description	Septin-8.

SEM6B_HUMAN
NC score	0.016307 (rank : 81)	θ value	1.06291 (rank : 13)
Query Neighborhood Hits	85	Target Neighborhood Hits	187	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H3T3, Q9NRK9	Gene names	SEMA6B, SEMAZ
Domain Architecture
Description	Semaphorin-6B precursor (Semaphorin Z) (Sema Z).

PRRT3_HUMAN
NC score	0.014917 (rank : 82)	θ value	6.88961 (rank : 66)
Query Neighborhood Hits	85	Target Neighborhood Hits	998	Shared Neighborhood Hits	15
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

IF4G1_HUMAN
NC score	0.012545 (rank : 83)	θ value	8.99809 (rank : 77)
Query Neighborhood Hits	85	Target Neighborhood Hits	347	Shared Neighborhood Hits	10
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

TNIK_HUMAN
NC score	0.011956 (rank : 84)	θ value	3.0926 (rank : 31)
Query Neighborhood Hits	85	Target Neighborhood Hits	1570	Shared Neighborhood Hits	41
SwissProt Accessions	Q9UKE5, O60298, Q8WUY7, Q9UKD8, Q9UKD9, Q9UKE0, Q9UKE1, Q9UKE2, Q9UKE3, Q9UKE4	Gene names	TNIK, KIAA0551
Domain Architecture
Description	TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1).

SMCA2_HUMAN
NC score	0.011106 (rank : 85)	θ value	6.88961 (rank : 67)
Query Neighborhood Hits	85	Target Neighborhood Hits	503	Shared Neighborhood Hits	16
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

NSD1_HUMAN
NC score	0.009737 (rank : 86)	θ value	8.99809 (rank : 79)
Query Neighborhood Hits	85	Target Neighborhood Hits	427	Shared Neighborhood Hits	5
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

ARHGC_HUMAN
NC score	0.008881 (rank : 87)	θ value	8.99809 (rank : 71)
Query Neighborhood Hits	85	Target Neighborhood Hits	351	Shared Neighborhood Hits	12
SwissProt Accessions	Q9NZN5, O15086	Gene names	ARHGEF12, KIAA0382, LARG
Domain Architecture
Description	Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF).

FOXN1_MOUSE
NC score	0.008736 (rank : 88)	θ value	6.88961 (rank : 60)
Query Neighborhood Hits	85	Target Neighborhood Hits	300	Shared Neighborhood Hits	4
SwissProt Accessions	Q61575	Gene names	Foxn1, Fkh19, Hfh11, Whn
Domain Architecture
Description	Forkhead box protein N1 (Transcription factor winged-helix nude) (Hepatocyte nuclear factor 3 forkhead homolog 11) (HNF-3/forkhead homolog 11) (HFH-11).

PAX9_HUMAN
NC score	0.008386 (rank : 89)	θ value	8.99809 (rank : 81)
Query Neighborhood Hits	85	Target Neighborhood Hits	92	Shared Neighborhood Hits	3
SwissProt Accessions	P55771, Q99582, Q9UQR4	Gene names	PAX9
Domain Architecture
Description	Paired box protein Pax-9.

PLXB1_HUMAN
NC score	0.008114 (rank : 90)	θ value	8.99809 (rank : 82)
Query Neighborhood Hits	85	Target Neighborhood Hits	360	Shared Neighborhood Hits	9
SwissProt Accessions	O43157, Q6NY20, Q9UIV7, Q9UJ92, Q9UJ93	Gene names	PLXNB1, KIAA0407, SEP
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor (Semaphorin receptor SEP).

TITIN_HUMAN
NC score	0.006605 (rank : 91)	θ value	8.99809 (rank : 84)
Query Neighborhood Hits	85	Target Neighborhood Hits	2923	Shared Neighborhood Hits	47
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

MAK_MOUSE
NC score	0.003751 (rank : 92)	θ value	3.0926 (rank : 29)
Query Neighborhood Hits	85	Target Neighborhood Hits	873	Shared Neighborhood Hits	8
SwissProt Accessions	Q04859	Gene names	Mak, Rck
Domain Architecture
Description	Serine/threonine-protein kinase MAK (EC 2.7.11.22) (Male germ cell- associated kinase) (Protein kinase RCK).

OBSCN_HUMAN
NC score	0.002890 (rank : 93)	θ value	8.99809 (rank : 80)
Query Neighborhood Hits	85	Target Neighborhood Hits	1931	Shared Neighborhood Hits	12
SwissProt Accessions	Q5VST9, Q2A664, Q5T7G8, Q5T7G9, Q5VSU2, Q86YC7, Q8NHN0, Q8NHN1, Q8NHN2, Q8NHN4, Q8NHN5, Q8NHN6, Q8NHN7, Q8NHN8, Q8NHN9, Q96AA2, Q9HCD3, Q9HCL6	Gene names	OBSCN, KIAA1556, KIAA1639
Domain Architecture	No domain graphic available
Description	Obscurin (Obscurin-myosin light chain kinase) (Obscurin-MLCK) (Obscurin-RhoGEF).

PRD16_HUMAN
NC score	0.001523 (rank : 94)	θ value	8.99809 (rank : 83)
Query Neighborhood Hits	85	Target Neighborhood Hits	832	Shared Neighborhood Hits	4
SwissProt Accessions	Q9HAZ2, Q8WYJ9, Q9C0I8	Gene names	PRDM16, KIAA1675, MEL1, PFM13
Domain Architecture
Description	PR domain zinc finger protein 16 (PR domain-containing protein 16) (Transcription factor MEL1).