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Network neighborhood for query Sequence : DNL4_MOUSE

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DNL4_MOUSE
SwissProt Accessions	Q8BTF7, Q3UG76	Gene names	Lig4
Domain Architecture	No domain graphic available
Description	DNA ligase 4 (EC 6.5.1.1) (DNA ligase IV) (Polydeoxyribonucleotide synthase [ATP] 4).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

DNL4_HUMAN
θ value	0 (rank : 1)	NC score	0.998148 (rank : 2)
Query Neighborhood Hits	17	Target Neighborhood Hits	14	Shared Neighborhood Hits	9
SwissProt Accessions	P49917, Q8IY66, Q8TEU5	Gene names	LIG4
Domain Architecture
Description	DNA ligase 4 (EC 6.5.1.1) (DNA ligase IV) (Polydeoxyribonucleotide synthase [ATP] 4).

DNL4_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	17	Target Neighborhood Hits	17	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BTF7, Q3UG76	Gene names	Lig4
Domain Architecture	No domain graphic available
Description	DNA ligase 4 (EC 6.5.1.1) (DNA ligase IV) (Polydeoxyribonucleotide synthase [ATP] 4).

DNL3_HUMAN
θ value	3.27365e-34 (rank : 3)	NC score	0.716215 (rank : 3)
Query Neighborhood Hits	17	Target Neighborhood Hits	49	Shared Neighborhood Hits	6
SwissProt Accessions	P49916, Q16714	Gene names	LIG3
Domain Architecture
Description	DNA ligase 3 (EC 6.5.1.1) (DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3).

DNL3_MOUSE
θ value	1.52067e-31 (rank : 4)	NC score	0.707095 (rank : 4)
Query Neighborhood Hits	17	Target Neighborhood Hits	37	Shared Neighborhood Hits	6
SwissProt Accessions	P97386, P97385	Gene names	Lig3
Domain Architecture
Description	DNA ligase 3 (EC 6.5.1.1) (DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3).

DNL1_MOUSE
θ value	2.59387e-31 (rank : 5)	NC score	0.683828 (rank : 5)
Query Neighborhood Hits	17	Target Neighborhood Hits	110	Shared Neighborhood Hits	7
SwissProt Accessions	P37913	Gene names	Lig1, Lig-1
Domain Architecture
Description	DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1).

DNL1_HUMAN
θ value	3.74554e-30 (rank : 6)	NC score	0.655516 (rank : 6)
Query Neighborhood Hits	17	Target Neighborhood Hits	216	Shared Neighborhood Hits	6
SwissProt Accessions	P18858	Gene names	LIG1
Domain Architecture
Description	DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1).

SM1L2_HUMAN
θ value	0.279714 (rank : 7)	NC score	0.021916 (rank : 10)
Query Neighborhood Hits	17	Target Neighborhood Hits	1019	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NDV3, Q5TIC3, Q9Y3G5	Gene names	SMC1L2
Domain Architecture
Description	Structural maintenance of chromosome 1-like 2 protein (SMC1beta protein).

DPOLL_MOUSE
θ value	0.813845 (rank : 8)	NC score	0.029301 (rank : 7)
Query Neighborhood Hits	17	Target Neighborhood Hits	71	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QXE2, Q9CTJ1	Gene names	Poll, Polk
Domain Architecture
Description	DNA polymerase lambda (EC 2.7.7.7) (EC 4.2.99.-) (Pol Lambda) (DNA polymerase kappa).

MY18A_HUMAN
θ value	2.36792 (rank : 9)	NC score	0.004917 (rank : 16)
Query Neighborhood Hits	17	Target Neighborhood Hits	1929	Shared Neighborhood Hits	4
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

TRI43_HUMAN
θ value	2.36792 (rank : 10)	NC score	0.013732 (rank : 13)
Query Neighborhood Hits	17	Target Neighborhood Hits	341	Shared Neighborhood Hits	3
SwissProt Accessions	Q96BQ3	Gene names	TRIM43
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 43.

DIAP2_MOUSE
θ value	4.03905 (rank : 11)	NC score	0.020148 (rank : 11)
Query Neighborhood Hits	17	Target Neighborhood Hits	260	Shared Neighborhood Hits	4
SwissProt Accessions	O70566, Q8C2G8	Gene names	Diaph2, Diap2
Domain Architecture
Description	Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2) (mDia3).

DGC14_HUMAN
θ value	5.27518 (rank : 12)	NC score	0.028025 (rank : 9)
Query Neighborhood Hits	17	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	Q96DF8, Q9BTZ4	Gene names	DGCR14, DGSI, ES2
Domain Architecture	No domain graphic available
Description	DGCR14 protein (DiGeorge syndrome critical region 14) (ES2 protein).

DGC14_MOUSE
θ value	5.27518 (rank : 13)	NC score	0.028064 (rank : 8)
Query Neighborhood Hits	17	Target Neighborhood Hits	35	Shared Neighborhood Hits	3
SwissProt Accessions	O70279, Q91YX1	Gene names	Dgcr14, Dgsi, Es2, Es2el
Domain Architecture	No domain graphic available
Description	DGCR14 protein (DiGeorge syndrome critical region 14 homolog) (ES2 protein) (Expressed sequence 2 embryonic lethal).

RBL2_HUMAN
θ value	6.88961 (rank : 14)	NC score	0.010355 (rank : 15)
Query Neighborhood Hits	17	Target Neighborhood Hits	44	Shared Neighborhood Hits	2
SwissProt Accessions	Q08999, Q15073, Q16084, Q92812	Gene names	RBL2, RB2
Domain Architecture
Description	Retinoblastoma-like protein 2 (130 kDa retinoblastoma-associated protein) (PRB2) (P130) (RBR-2).

SENP6_HUMAN
θ value	6.88961 (rank : 15)	NC score	0.016384 (rank : 12)
Query Neighborhood Hits	17	Target Neighborhood Hits	69	Shared Neighborhood Hits	2
SwissProt Accessions	Q9GZR1, O94891, Q8TBY4, Q9UJV5	Gene names	SENP6, KIAA0797, SSP1, SUSP1
Domain Architecture
Description	Sentrin-specific protease 6 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP6) (SUMO-1-specific protease 1).

AMGO1_MOUSE
θ value	8.99809 (rank : 16)	NC score	0.003820 (rank : 17)
Query Neighborhood Hits	17	Target Neighborhood Hits	325	Shared Neighborhood Hits	2
SwissProt Accessions	Q80ZD8, Q69ZQ0, Q8R5D4, Q921U9	Gene names	Amigo1, Ali2, Amigo, Kiaa1163
Domain Architecture	No domain graphic available
Description	Amphoterin-induced protein 1 precursor (AMIGO-1) (Alivin-2).

DIAP2_HUMAN
θ value	8.99809 (rank : 17)	NC score	0.011276 (rank : 14)
Query Neighborhood Hits	17	Target Neighborhood Hits	342	Shared Neighborhood Hits	4
SwissProt Accessions	O60879, O60878, Q8WX06, Q8WX48, Q9UJL2	Gene names	DIAPH2, DIA
Domain Architecture
Description	Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2).

Hits sorted by NC score

DNL4_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	17	Target Neighborhood Hits	17	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BTF7, Q3UG76	Gene names	Lig4
Domain Architecture	No domain graphic available
Description	DNA ligase 4 (EC 6.5.1.1) (DNA ligase IV) (Polydeoxyribonucleotide synthase [ATP] 4).

DNL4_HUMAN
NC score	0.998148 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	17	Target Neighborhood Hits	14	Shared Neighborhood Hits	9
SwissProt Accessions	P49917, Q8IY66, Q8TEU5	Gene names	LIG4
Domain Architecture
Description	DNA ligase 4 (EC 6.5.1.1) (DNA ligase IV) (Polydeoxyribonucleotide synthase [ATP] 4).

DNL3_HUMAN
NC score	0.716215 (rank : 3)	θ value	3.27365e-34 (rank : 3)
Query Neighborhood Hits	17	Target Neighborhood Hits	49	Shared Neighborhood Hits	6
SwissProt Accessions	P49916, Q16714	Gene names	LIG3
Domain Architecture
Description	DNA ligase 3 (EC 6.5.1.1) (DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3).

DNL3_MOUSE
NC score	0.707095 (rank : 4)	θ value	1.52067e-31 (rank : 4)
Query Neighborhood Hits	17	Target Neighborhood Hits	37	Shared Neighborhood Hits	6
SwissProt Accessions	P97386, P97385	Gene names	Lig3
Domain Architecture
Description	DNA ligase 3 (EC 6.5.1.1) (DNA ligase III) (Polydeoxyribonucleotide synthase [ATP] 3).

DNL1_MOUSE
NC score	0.683828 (rank : 5)	θ value	2.59387e-31 (rank : 5)
Query Neighborhood Hits	17	Target Neighborhood Hits	110	Shared Neighborhood Hits	7
SwissProt Accessions	P37913	Gene names	Lig1, Lig-1
Domain Architecture
Description	DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1).

DNL1_HUMAN
NC score	0.655516 (rank : 6)	θ value	3.74554e-30 (rank : 6)
Query Neighborhood Hits	17	Target Neighborhood Hits	216	Shared Neighborhood Hits	6
SwissProt Accessions	P18858	Gene names	LIG1
Domain Architecture
Description	DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1).

DPOLL_MOUSE
NC score	0.029301 (rank : 7)	θ value	0.813845 (rank : 8)
Query Neighborhood Hits	17	Target Neighborhood Hits	71	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QXE2, Q9CTJ1	Gene names	Poll, Polk
Domain Architecture
Description	DNA polymerase lambda (EC 2.7.7.7) (EC 4.2.99.-) (Pol Lambda) (DNA polymerase kappa).

DGC14_MOUSE
NC score	0.028064 (rank : 8)	θ value	5.27518 (rank : 13)
Query Neighborhood Hits	17	Target Neighborhood Hits	35	Shared Neighborhood Hits	3
SwissProt Accessions	O70279, Q91YX1	Gene names	Dgcr14, Dgsi, Es2, Es2el
Domain Architecture	No domain graphic available
Description	DGCR14 protein (DiGeorge syndrome critical region 14 homolog) (ES2 protein) (Expressed sequence 2 embryonic lethal).

DGC14_HUMAN
NC score	0.028025 (rank : 9)	θ value	5.27518 (rank : 12)
Query Neighborhood Hits	17	Target Neighborhood Hits	36	Shared Neighborhood Hits	3
SwissProt Accessions	Q96DF8, Q9BTZ4	Gene names	DGCR14, DGSI, ES2
Domain Architecture	No domain graphic available
Description	DGCR14 protein (DiGeorge syndrome critical region 14) (ES2 protein).

SM1L2_HUMAN
NC score	0.021916 (rank : 10)	θ value	0.279714 (rank : 7)
Query Neighborhood Hits	17	Target Neighborhood Hits	1019	Shared Neighborhood Hits	5
SwissProt Accessions	Q8NDV3, Q5TIC3, Q9Y3G5	Gene names	SMC1L2
Domain Architecture
Description	Structural maintenance of chromosome 1-like 2 protein (SMC1beta protein).

DIAP2_MOUSE
NC score	0.020148 (rank : 11)	θ value	4.03905 (rank : 11)
Query Neighborhood Hits	17	Target Neighborhood Hits	260	Shared Neighborhood Hits	4
SwissProt Accessions	O70566, Q8C2G8	Gene names	Diaph2, Diap2
Domain Architecture
Description	Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2) (mDia3).

SENP6_HUMAN
NC score	0.016384 (rank : 12)	θ value	6.88961 (rank : 15)
Query Neighborhood Hits	17	Target Neighborhood Hits	69	Shared Neighborhood Hits	2
SwissProt Accessions	Q9GZR1, O94891, Q8TBY4, Q9UJV5	Gene names	SENP6, KIAA0797, SSP1, SUSP1
Domain Architecture
Description	Sentrin-specific protease 6 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP6) (SUMO-1-specific protease 1).

TRI43_HUMAN
NC score	0.013732 (rank : 13)	θ value	2.36792 (rank : 10)
Query Neighborhood Hits	17	Target Neighborhood Hits	341	Shared Neighborhood Hits	3
SwissProt Accessions	Q96BQ3	Gene names	TRIM43
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 43.

DIAP2_HUMAN
NC score	0.011276 (rank : 14)	θ value	8.99809 (rank : 17)
Query Neighborhood Hits	17	Target Neighborhood Hits	342	Shared Neighborhood Hits	4
SwissProt Accessions	O60879, O60878, Q8WX06, Q8WX48, Q9UJL2	Gene names	DIAPH2, DIA
Domain Architecture
Description	Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2).

RBL2_HUMAN
NC score	0.010355 (rank : 15)	θ value	6.88961 (rank : 14)
Query Neighborhood Hits	17	Target Neighborhood Hits	44	Shared Neighborhood Hits	2
SwissProt Accessions	Q08999, Q15073, Q16084, Q92812	Gene names	RBL2, RB2
Domain Architecture
Description	Retinoblastoma-like protein 2 (130 kDa retinoblastoma-associated protein) (PRB2) (P130) (RBR-2).

MY18A_HUMAN
NC score	0.004917 (rank : 16)	θ value	2.36792 (rank : 9)
Query Neighborhood Hits	17	Target Neighborhood Hits	1929	Shared Neighborhood Hits	4
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

AMGO1_MOUSE
NC score	0.003820 (rank : 17)	θ value	8.99809 (rank : 16)
Query Neighborhood Hits	17	Target Neighborhood Hits	325	Shared Neighborhood Hits	2
SwissProt Accessions	Q80ZD8, Q69ZQ0, Q8R5D4, Q921U9	Gene names	Amigo1, Ali2, Amigo, Kiaa1163
Domain Architecture	No domain graphic available
Description	Amphoterin-induced protein 1 precursor (AMIGO-1) (Alivin-2).