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Network neighborhood for query Sequence : FOLC_MOUSE

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FOLC_MOUSE
SwissProt Accessions	P48760	Gene names	Fpgs
Domain Architecture
Description	Folylpolyglutamate synthase, mitochondrial precursor (EC 6.3.2.17) (Folylpoly-gamma-glutamate synthetase) (FPGS) (Tetrahydrofolate synthase) (Tetrahydrofolylpolyglutamate synthase).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

FOLC_HUMAN
θ value	0 (rank : 1)	NC score	0.995007 (rank : 2)
Query Neighborhood Hits	11	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q05932	Gene names	FPGS
Domain Architecture
Description	Folylpolyglutamate synthase, mitochondrial precursor (EC 6.3.2.17) (Folylpoly-gamma-glutamate synthetase) (FPGS) (Tetrahydrofolate synthase) (Tetrahydrofolylpolyglutamate synthase).

FOLC_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	11	Target Neighborhood Hits	11	Shared Neighborhood Hits	11
SwissProt Accessions	P48760	Gene names	Fpgs
Domain Architecture
Description	Folylpolyglutamate synthase, mitochondrial precursor (EC 6.3.2.17) (Folylpoly-gamma-glutamate synthetase) (FPGS) (Tetrahydrofolate synthase) (Tetrahydrofolylpolyglutamate synthase).

DHX36_MOUSE
θ value	0.47712 (rank : 3)	NC score	0.021883 (rank : 8)
Query Neighborhood Hits	11	Target Neighborhood Hits	114	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VHK9, Q6ZPP7, Q9CSE8	Gene names	Dhx36, Ddx36, Kiaa1488, Mlel1
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX36 (EC 3.6.1.-) (DEAH box protein 36) (MLE-like protein 1) (RNA helicase associated with AU-rich element ARE).

EXTL2_HUMAN
θ value	0.813845 (rank : 4)	NC score	0.037320 (rank : 5)
Query Neighborhood Hits	11	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UBQ6	Gene names	EXTL2, EXTR2
Domain Architecture	No domain graphic available
Description	Exostosin-like 2 (EC 2.4.1.223) (Glucuronyl-galactosyl-proteoglycan 4- alpha-N-acetylglucosaminyltransferase) (Alpha-1,4-N- acetylhexosaminyltransferase EXTL2) (Alpha-GalNAcT EXTL2) (EXT-related protein 2).

DOS_HUMAN
θ value	1.06291 (rank : 5)	NC score	0.059764 (rank : 3)
Query Neighborhood Hits	11	Target Neighborhood Hits	68	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N350, O43385	Gene names	DOS, C19orf26
Domain Architecture	No domain graphic available
Description	Protein Dos.

F8I2_MOUSE
θ value	1.06291 (rank : 6)	NC score	0.049823 (rank : 4)
Query Neighborhood Hits	11	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	Q00558	Gene names	F8a1, F8a
Domain Architecture	No domain graphic available
Description	Factor VIII intron 22 protein (CpG island protein).

WFS1_HUMAN
θ value	4.03905 (rank : 7)	NC score	0.024837 (rank : 7)
Query Neighborhood Hits	11	Target Neighborhood Hits	42	Shared Neighborhood Hits	2
SwissProt Accessions	O76024, Q8N6I3, Q9UNW6	Gene names	WFS1
Domain Architecture	No domain graphic available
Description	Wolframin.

NUAK1_HUMAN
θ value	5.27518 (rank : 8)	NC score	0.001529 (rank : 11)
Query Neighborhood Hits	11	Target Neighborhood Hits	874	Shared Neighborhood Hits	2
SwissProt Accessions	O60285, Q96KA8	Gene names	NUAK1, ARK5, KIAA0537
Domain Architecture	No domain graphic available
Description	NUAK family SNF1-like kinase 1 (EC 2.7.11.1) (AMPK-related protein kinase 5).

SPAT4_MOUSE
θ value	5.27518 (rank : 9)	NC score	0.025704 (rank : 6)
Query Neighborhood Hits	11	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K3V1, Q923U8	Gene names	Spata4, Srg2, Tsarg2
Domain Architecture
Description	Spermatogenesis-associated protein 4 (Testis spermatocyte apoptosis- related gene 2 protein) (Testis and spermatogenesis cell-related protein 2) (Spermatogenesis-related gene 2 protein).

ALMS1_MOUSE
θ value	6.88961 (rank : 10)	NC score	0.016482 (rank : 9)
Query Neighborhood Hits	11	Target Neighborhood Hits	181	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K4E0, Q6A084, Q8C9N9	Gene names	Alms1, Kiaa0328
Domain Architecture	No domain graphic available
Description	Alstrom syndrome protein 1 homolog.

ROBO2_HUMAN
θ value	6.88961 (rank : 11)	NC score	0.004157 (rank : 10)
Query Neighborhood Hits	11	Target Neighborhood Hits	479	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HCK4, O43608	Gene names	ROBO2, KIAA1568
Domain Architecture
Description	Roundabout homolog 2 precursor.

Hits sorted by NC score

FOLC_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	11	Target Neighborhood Hits	11	Shared Neighborhood Hits	11
SwissProt Accessions	P48760	Gene names	Fpgs
Domain Architecture
Description	Folylpolyglutamate synthase, mitochondrial precursor (EC 6.3.2.17) (Folylpoly-gamma-glutamate synthetase) (FPGS) (Tetrahydrofolate synthase) (Tetrahydrofolylpolyglutamate synthase).

FOLC_HUMAN
NC score	0.995007 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	11	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q05932	Gene names	FPGS
Domain Architecture
Description	Folylpolyglutamate synthase, mitochondrial precursor (EC 6.3.2.17) (Folylpoly-gamma-glutamate synthetase) (FPGS) (Tetrahydrofolate synthase) (Tetrahydrofolylpolyglutamate synthase).

DOS_HUMAN
NC score	0.059764 (rank : 3)	θ value	1.06291 (rank : 5)
Query Neighborhood Hits	11	Target Neighborhood Hits	68	Shared Neighborhood Hits	2
SwissProt Accessions	Q8N350, O43385	Gene names	DOS, C19orf26
Domain Architecture	No domain graphic available
Description	Protein Dos.

F8I2_MOUSE
NC score	0.049823 (rank : 4)	θ value	1.06291 (rank : 6)
Query Neighborhood Hits	11	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	Q00558	Gene names	F8a1, F8a
Domain Architecture	No domain graphic available
Description	Factor VIII intron 22 protein (CpG island protein).

EXTL2_HUMAN
NC score	0.037320 (rank : 5)	θ value	0.813845 (rank : 4)
Query Neighborhood Hits	11	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UBQ6	Gene names	EXTL2, EXTR2
Domain Architecture	No domain graphic available
Description	Exostosin-like 2 (EC 2.4.1.223) (Glucuronyl-galactosyl-proteoglycan 4- alpha-N-acetylglucosaminyltransferase) (Alpha-1,4-N- acetylhexosaminyltransferase EXTL2) (Alpha-GalNAcT EXTL2) (EXT-related protein 2).

SPAT4_MOUSE
NC score	0.025704 (rank : 6)	θ value	5.27518 (rank : 9)
Query Neighborhood Hits	11	Target Neighborhood Hits	6	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K3V1, Q923U8	Gene names	Spata4, Srg2, Tsarg2
Domain Architecture
Description	Spermatogenesis-associated protein 4 (Testis spermatocyte apoptosis- related gene 2 protein) (Testis and spermatogenesis cell-related protein 2) (Spermatogenesis-related gene 2 protein).

WFS1_HUMAN
NC score	0.024837 (rank : 7)	θ value	4.03905 (rank : 7)
Query Neighborhood Hits	11	Target Neighborhood Hits	42	Shared Neighborhood Hits	2
SwissProt Accessions	O76024, Q8N6I3, Q9UNW6	Gene names	WFS1
Domain Architecture	No domain graphic available
Description	Wolframin.

DHX36_MOUSE
NC score	0.021883 (rank : 8)	θ value	0.47712 (rank : 3)
Query Neighborhood Hits	11	Target Neighborhood Hits	114	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VHK9, Q6ZPP7, Q9CSE8	Gene names	Dhx36, Ddx36, Kiaa1488, Mlel1
Domain Architecture	No domain graphic available
Description	Probable ATP-dependent RNA helicase DHX36 (EC 3.6.1.-) (DEAH box protein 36) (MLE-like protein 1) (RNA helicase associated with AU-rich element ARE).

ALMS1_MOUSE
NC score	0.016482 (rank : 9)	θ value	6.88961 (rank : 10)
Query Neighborhood Hits	11	Target Neighborhood Hits	181	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K4E0, Q6A084, Q8C9N9	Gene names	Alms1, Kiaa0328
Domain Architecture	No domain graphic available
Description	Alstrom syndrome protein 1 homolog.

ROBO2_HUMAN
NC score	0.004157 (rank : 10)	θ value	6.88961 (rank : 11)
Query Neighborhood Hits	11	Target Neighborhood Hits	479	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HCK4, O43608	Gene names	ROBO2, KIAA1568
Domain Architecture
Description	Roundabout homolog 2 precursor.

NUAK1_HUMAN
NC score	0.001529 (rank : 11)	θ value	5.27518 (rank : 8)
Query Neighborhood Hits	11	Target Neighborhood Hits	874	Shared Neighborhood Hits	2
SwissProt Accessions	O60285, Q96KA8	Gene names	NUAK1, ARK5, KIAA0537
Domain Architecture	No domain graphic available
Description	NUAK family SNF1-like kinase 1 (EC 2.7.11.1) (AMPK-related protein kinase 5).