Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : EXTL2_HUMAN

For an explanation of this page, click here

EXTL2_HUMAN
SwissProt Accessions	Q9UBQ6	Gene names	EXTL2, EXTR2
Domain Architecture	No domain graphic available
Description	Exostosin-like 2 (EC 2.4.1.223) (Glucuronyl-galactosyl-proteoglycan 4- alpha-N-acetylglucosaminyltransferase) (Alpha-1,4-N- acetylhexosaminyltransferase EXTL2) (Alpha-GalNAcT EXTL2) (EXT-related protein 2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

EXTL2_HUMAN
θ value	6.99473e-178 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	15	Target Neighborhood Hits	15	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UBQ6	Gene names	EXTL2, EXTR2
Domain Architecture	No domain graphic available
Description	Exostosin-like 2 (EC 2.4.1.223) (Glucuronyl-galactosyl-proteoglycan 4- alpha-N-acetylglucosaminyltransferase) (Alpha-1,4-N- acetylhexosaminyltransferase EXTL2) (Alpha-GalNAcT EXTL2) (EXT-related protein 2).

EXTL2_MOUSE
θ value	1.16101e-156 (rank : 2)	NC score	0.998839 (rank : 2)
Query Neighborhood Hits	15	Target Neighborhood Hits	11	Shared Neighborhood Hits	11
SwissProt Accessions	Q9ES89, Q505Q8, Q9CX90	Gene names	Extl2, Extr2
Domain Architecture
Description	Exostosin-like 2 (EC 2.4.1.223) (Glucuronyl-galactosyl-proteoglycan 4- alpha-N-acetylglucosaminyltransferase) (Alpha-1,4-N- acetylhexosaminyltransferase EXTL2) (Alpha-GalNAcT EXTL2) (EXT-related protein 2).

EXT2_MOUSE
θ value	1.79631e-32 (rank : 3)	NC score	0.840704 (rank : 3)
Query Neighborhood Hits	15	Target Neighborhood Hits	17	Shared Neighborhood Hits	10
SwissProt Accessions	P70428, P70395, Q923D6	Gene names	Ext2
Domain Architecture
Description	Exostosin-2 (EC 2.4.1.224) (EC 2.4.1.225) (Glucuronosyl-N- acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4- alpha-N-acetylglucosaminyltransferase) (Multiple exostoses protein 2 homolog).

EXT2_HUMAN
θ value	2.34606e-32 (rank : 4)	NC score	0.840059 (rank : 4)
Query Neighborhood Hits	15	Target Neighborhood Hits	20	Shared Neighborhood Hits	10
SwissProt Accessions	Q93063, O15288	Gene names	EXT2
Domain Architecture
Description	Exostosin-2 (EC 2.4.1.224) (EC 2.4.1.225) (Glucuronosyl-N- acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4- alpha-N-acetylglucosaminyltransferase) (Putative tumor suppressor protein EXT2) (Multiple exostoses protein 2).

EXTL3_HUMAN
θ value	3.06405e-32 (rank : 5)	NC score	0.821771 (rank : 6)
Query Neighborhood Hits	15	Target Neighborhood Hits	113	Shared Neighborhood Hits	10
SwissProt Accessions	O43909, O00225	Gene names	EXTL3, EXTL1L, EXTR1, KIAA0519
Domain Architecture
Description	Exostosin-like 3 (EC 2.4.1.223) (Glucuronyl-galactosyl-proteoglycan 4- alpha-N-acetylglucosaminyltransferase) (Putative tumor suppressor protein EXTL3) (Multiple exostosis-like protein 3) (Hereditary multiple exostoses gene isolog) (EXT-related protein 1).

EXTL3_MOUSE
θ value	5.22648e-32 (rank : 6)	NC score	0.822059 (rank : 5)
Query Neighborhood Hits	15	Target Neighborhood Hits	108	Shared Neighborhood Hits	10
SwissProt Accessions	Q9WVL6	Gene names	Extl3
Domain Architecture
Description	Exostosin-like 3 (EC 2.4.1.-) (Multiple exostosis-like protein 3).

EXT1_MOUSE
θ value	5.79196e-23 (rank : 7)	NC score	0.790558 (rank : 7)
Query Neighborhood Hits	15	Target Neighborhood Hits	18	Shared Neighborhood Hits	10
SwissProt Accessions	P97464, Q61546	Gene names	Ext1
Domain Architecture
Description	Exostosin-1 (EC 2.4.1.224) (EC 2.4.1.225) (Glucuronosyl-N- acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4- alpha-N-acetylglucosaminyltransferase) (Multiple exostoses protein 1 homolog).

EXT1_HUMAN
θ value	7.56453e-23 (rank : 8)	NC score	0.790240 (rank : 8)
Query Neighborhood Hits	15	Target Neighborhood Hits	17	Shared Neighborhood Hits	10
SwissProt Accessions	Q16394, Q9BVI9	Gene names	EXT1
Domain Architecture
Description	Exostosin-1 (EC 2.4.1.224) (EC 2.4.1.225) (Glucuronosyl-N- acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4- alpha-N-acetylglucosaminyltransferase) (Putative tumor suppressor protein EXT1) (Multiple exostoses protein 1).

EXTL1_MOUSE
θ value	5.07402e-19 (rank : 9)	NC score	0.770914 (rank : 9)
Query Neighborhood Hits	15	Target Neighborhood Hits	26	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JKV7	Gene names	Extl1
Domain Architecture
Description	Exostosin-like 1 (EC 2.4.1.224) (Glucuronosyl-N-acetylglucosaminyl- proteoglycan 4-alpha-N-acetylglucosaminyltransferase) (Exostosin-L) (Multiple exostosis-like protein).

EXTL1_HUMAN
θ value	3.40345e-15 (rank : 10)	NC score	0.756634 (rank : 10)
Query Neighborhood Hits	15	Target Neighborhood Hits	18	Shared Neighborhood Hits	10
SwissProt Accessions	Q92935, Q6GSC1	Gene names	EXTL1, EXTL
Domain Architecture
Description	Exostosin-like 1 (EC 2.4.1.224) (Glucuronosyl-N-acetylglucosaminyl- proteoglycan 4-alpha-N-acetylglucosaminyltransferase) (Exostosin-L) (Multiple exostosis-like protein).

FOLC_MOUSE
θ value	0.813845 (rank : 11)	NC score	0.037320 (rank : 11)
Query Neighborhood Hits	15	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	P48760	Gene names	Fpgs
Domain Architecture
Description	Folylpolyglutamate synthase, mitochondrial precursor (EC 6.3.2.17) (Folylpoly-gamma-glutamate synthetase) (FPGS) (Tetrahydrofolate synthase) (Tetrahydrofolylpolyglutamate synthase).

SPB9_HUMAN
θ value	4.03905 (rank : 12)	NC score	0.004799 (rank : 15)
Query Neighborhood Hits	15	Target Neighborhood Hits	81	Shared Neighborhood Hits	2
SwissProt Accessions	P50453	Gene names	SERPINB9, PI9
Domain Architecture
Description	Serpin B9 (Cytoplasmic antiproteinase 3) (CAP-3) (CAP3) (Protease inhibitor 9).

PADI3_MOUSE
θ value	6.88961 (rank : 13)	NC score	0.015018 (rank : 12)
Query Neighborhood Hits	15	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z184	Gene names	Padi3, Pdi3
Domain Architecture
Description	Protein-arginine deiminase type-3 (EC 3.5.3.15) (Protein-arginine deiminase type III) (Peptidylarginine deiminase III).

UBP10_HUMAN
θ value	6.88961 (rank : 14)	NC score	0.009469 (rank : 14)
Query Neighborhood Hits	15	Target Neighborhood Hits	153	Shared Neighborhood Hits	2
SwissProt Accessions	Q14694, Q9BWG7, Q9NSL7	Gene names	USP10, KIAA0190
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

PADI2_MOUSE
θ value	8.99809 (rank : 15)	NC score	0.009685 (rank : 13)
Query Neighborhood Hits	15	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q08642	Gene names	Padi2, Pdi, Pdi2
Domain Architecture
Description	Protein-arginine deiminase type-2 (EC 3.5.3.15) (Protein-arginine deiminase type II) (Peptidylarginine deiminase II).

Hits sorted by NC score

EXTL2_HUMAN
NC score	0.999962 (rank : 1)	θ value	6.99473e-178 (rank : 1)
Query Neighborhood Hits	15	Target Neighborhood Hits	15	Shared Neighborhood Hits	15
SwissProt Accessions	Q9UBQ6	Gene names	EXTL2, EXTR2
Domain Architecture	No domain graphic available
Description	Exostosin-like 2 (EC 2.4.1.223) (Glucuronyl-galactosyl-proteoglycan 4- alpha-N-acetylglucosaminyltransferase) (Alpha-1,4-N- acetylhexosaminyltransferase EXTL2) (Alpha-GalNAcT EXTL2) (EXT-related protein 2).

EXTL2_MOUSE
NC score	0.998839 (rank : 2)	θ value	1.16101e-156 (rank : 2)
Query Neighborhood Hits	15	Target Neighborhood Hits	11	Shared Neighborhood Hits	11
SwissProt Accessions	Q9ES89, Q505Q8, Q9CX90	Gene names	Extl2, Extr2
Domain Architecture
Description	Exostosin-like 2 (EC 2.4.1.223) (Glucuronyl-galactosyl-proteoglycan 4- alpha-N-acetylglucosaminyltransferase) (Alpha-1,4-N- acetylhexosaminyltransferase EXTL2) (Alpha-GalNAcT EXTL2) (EXT-related protein 2).

EXT2_MOUSE
NC score	0.840704 (rank : 3)	θ value	1.79631e-32 (rank : 3)
Query Neighborhood Hits	15	Target Neighborhood Hits	17	Shared Neighborhood Hits	10
SwissProt Accessions	P70428, P70395, Q923D6	Gene names	Ext2
Domain Architecture
Description	Exostosin-2 (EC 2.4.1.224) (EC 2.4.1.225) (Glucuronosyl-N- acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4- alpha-N-acetylglucosaminyltransferase) (Multiple exostoses protein 2 homolog).

EXT2_HUMAN
NC score	0.840059 (rank : 4)	θ value	2.34606e-32 (rank : 4)
Query Neighborhood Hits	15	Target Neighborhood Hits	20	Shared Neighborhood Hits	10
SwissProt Accessions	Q93063, O15288	Gene names	EXT2
Domain Architecture
Description	Exostosin-2 (EC 2.4.1.224) (EC 2.4.1.225) (Glucuronosyl-N- acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4- alpha-N-acetylglucosaminyltransferase) (Putative tumor suppressor protein EXT2) (Multiple exostoses protein 2).

EXTL3_MOUSE
NC score	0.822059 (rank : 5)	θ value	5.22648e-32 (rank : 6)
Query Neighborhood Hits	15	Target Neighborhood Hits	108	Shared Neighborhood Hits	10
SwissProt Accessions	Q9WVL6	Gene names	Extl3
Domain Architecture
Description	Exostosin-like 3 (EC 2.4.1.-) (Multiple exostosis-like protein 3).

EXTL3_HUMAN
NC score	0.821771 (rank : 6)	θ value	3.06405e-32 (rank : 5)
Query Neighborhood Hits	15	Target Neighborhood Hits	113	Shared Neighborhood Hits	10
SwissProt Accessions	O43909, O00225	Gene names	EXTL3, EXTL1L, EXTR1, KIAA0519
Domain Architecture
Description	Exostosin-like 3 (EC 2.4.1.223) (Glucuronyl-galactosyl-proteoglycan 4- alpha-N-acetylglucosaminyltransferase) (Putative tumor suppressor protein EXTL3) (Multiple exostosis-like protein 3) (Hereditary multiple exostoses gene isolog) (EXT-related protein 1).

EXT1_MOUSE
NC score	0.790558 (rank : 7)	θ value	5.79196e-23 (rank : 7)
Query Neighborhood Hits	15	Target Neighborhood Hits	18	Shared Neighborhood Hits	10
SwissProt Accessions	P97464, Q61546	Gene names	Ext1
Domain Architecture
Description	Exostosin-1 (EC 2.4.1.224) (EC 2.4.1.225) (Glucuronosyl-N- acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4- alpha-N-acetylglucosaminyltransferase) (Multiple exostoses protein 1 homolog).

EXT1_HUMAN
NC score	0.790240 (rank : 8)	θ value	7.56453e-23 (rank : 8)
Query Neighborhood Hits	15	Target Neighborhood Hits	17	Shared Neighborhood Hits	10
SwissProt Accessions	Q16394, Q9BVI9	Gene names	EXT1
Domain Architecture
Description	Exostosin-1 (EC 2.4.1.224) (EC 2.4.1.225) (Glucuronosyl-N- acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4- alpha-N-acetylglucosaminyltransferase) (Putative tumor suppressor protein EXT1) (Multiple exostoses protein 1).

EXTL1_MOUSE
NC score	0.770914 (rank : 9)	θ value	5.07402e-19 (rank : 9)
Query Neighborhood Hits	15	Target Neighborhood Hits	26	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JKV7	Gene names	Extl1
Domain Architecture
Description	Exostosin-like 1 (EC 2.4.1.224) (Glucuronosyl-N-acetylglucosaminyl- proteoglycan 4-alpha-N-acetylglucosaminyltransferase) (Exostosin-L) (Multiple exostosis-like protein).

EXTL1_HUMAN
NC score	0.756634 (rank : 10)	θ value	3.40345e-15 (rank : 10)
Query Neighborhood Hits	15	Target Neighborhood Hits	18	Shared Neighborhood Hits	10
SwissProt Accessions	Q92935, Q6GSC1	Gene names	EXTL1, EXTL
Domain Architecture
Description	Exostosin-like 1 (EC 2.4.1.224) (Glucuronosyl-N-acetylglucosaminyl- proteoglycan 4-alpha-N-acetylglucosaminyltransferase) (Exostosin-L) (Multiple exostosis-like protein).

FOLC_MOUSE
NC score	0.037320 (rank : 11)	θ value	0.813845 (rank : 11)
Query Neighborhood Hits	15	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	P48760	Gene names	Fpgs
Domain Architecture
Description	Folylpolyglutamate synthase, mitochondrial precursor (EC 6.3.2.17) (Folylpoly-gamma-glutamate synthetase) (FPGS) (Tetrahydrofolate synthase) (Tetrahydrofolylpolyglutamate synthase).

PADI3_MOUSE
NC score	0.015018 (rank : 12)	θ value	6.88961 (rank : 13)
Query Neighborhood Hits	15	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z184	Gene names	Padi3, Pdi3
Domain Architecture
Description	Protein-arginine deiminase type-3 (EC 3.5.3.15) (Protein-arginine deiminase type III) (Peptidylarginine deiminase III).

PADI2_MOUSE
NC score	0.009685 (rank : 13)	θ value	8.99809 (rank : 15)
Query Neighborhood Hits	15	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q08642	Gene names	Padi2, Pdi, Pdi2
Domain Architecture
Description	Protein-arginine deiminase type-2 (EC 3.5.3.15) (Protein-arginine deiminase type II) (Peptidylarginine deiminase II).

UBP10_HUMAN
NC score	0.009469 (rank : 14)	θ value	6.88961 (rank : 14)
Query Neighborhood Hits	15	Target Neighborhood Hits	153	Shared Neighborhood Hits	2
SwissProt Accessions	Q14694, Q9BWG7, Q9NSL7	Gene names	USP10, KIAA0190
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.1.2.15) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10) (Deubiquitinating enzyme 10).

SPB9_HUMAN
NC score	0.004799 (rank : 15)	θ value	4.03905 (rank : 12)
Query Neighborhood Hits	15	Target Neighborhood Hits	81	Shared Neighborhood Hits	2
SwissProt Accessions	P50453	Gene names	SERPINB9, PI9
Domain Architecture
Description	Serpin B9 (Cytoplasmic antiproteinase 3) (CAP-3) (CAP3) (Protease inhibitor 9).