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Network neighborhood for query Sequence : EXT1_HUMAN

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EXT1_HUMAN
SwissProt Accessions	Q16394, Q9BVI9	Gene names	EXT1
Domain Architecture
Description	Exostosin-1 (EC 2.4.1.224) (EC 2.4.1.225) (Glucuronosyl-N- acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4- alpha-N-acetylglucosaminyltransferase) (Putative tumor suppressor protein EXT1) (Multiple exostoses protein 1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

EXT1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	17	Target Neighborhood Hits	17	Shared Neighborhood Hits	17
SwissProt Accessions	Q16394, Q9BVI9	Gene names	EXT1
Domain Architecture
Description	Exostosin-1 (EC 2.4.1.224) (EC 2.4.1.225) (Glucuronosyl-N- acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4- alpha-N-acetylglucosaminyltransferase) (Putative tumor suppressor protein EXT1) (Multiple exostoses protein 1).

EXT1_MOUSE
θ value	0 (rank : 2)	NC score	0.999916 (rank : 2)
Query Neighborhood Hits	17	Target Neighborhood Hits	18	Shared Neighborhood Hits	17
SwissProt Accessions	P97464, Q61546	Gene names	Ext1
Domain Architecture
Description	Exostosin-1 (EC 2.4.1.224) (EC 2.4.1.225) (Glucuronosyl-N- acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4- alpha-N-acetylglucosaminyltransferase) (Multiple exostoses protein 1 homolog).

EXTL1_HUMAN
θ value	7.04359e-154 (rank : 3)	NC score	0.975747 (rank : 3)
Query Neighborhood Hits	17	Target Neighborhood Hits	18	Shared Neighborhood Hits	10
SwissProt Accessions	Q92935, Q6GSC1	Gene names	EXTL1, EXTL
Domain Architecture
Description	Exostosin-like 1 (EC 2.4.1.224) (Glucuronosyl-N-acetylglucosaminyl- proteoglycan 4-alpha-N-acetylglucosaminyltransferase) (Exostosin-L) (Multiple exostosis-like protein).

EXTL1_MOUSE
θ value	1.62381e-150 (rank : 4)	NC score	0.973938 (rank : 4)
Query Neighborhood Hits	17	Target Neighborhood Hits	26	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JKV7	Gene names	Extl1
Domain Architecture
Description	Exostosin-like 1 (EC 2.4.1.224) (Glucuronosyl-N-acetylglucosaminyl- proteoglycan 4-alpha-N-acetylglucosaminyltransferase) (Exostosin-L) (Multiple exostosis-like protein).

EXT2_HUMAN
θ value	1.8752e-114 (rank : 5)	NC score	0.947409 (rank : 5)
Query Neighborhood Hits	17	Target Neighborhood Hits	20	Shared Neighborhood Hits	10
SwissProt Accessions	Q93063, O15288	Gene names	EXT2
Domain Architecture
Description	Exostosin-2 (EC 2.4.1.224) (EC 2.4.1.225) (Glucuronosyl-N- acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4- alpha-N-acetylglucosaminyltransferase) (Putative tumor suppressor protein EXT2) (Multiple exostoses protein 2).

EXT2_MOUSE
θ value	1.02895e-112 (rank : 6)	NC score	0.947188 (rank : 6)
Query Neighborhood Hits	17	Target Neighborhood Hits	17	Shared Neighborhood Hits	10
SwissProt Accessions	P70428, P70395, Q923D6	Gene names	Ext2
Domain Architecture
Description	Exostosin-2 (EC 2.4.1.224) (EC 2.4.1.225) (Glucuronosyl-N- acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4- alpha-N-acetylglucosaminyltransferase) (Multiple exostoses protein 2 homolog).

EXTL3_HUMAN
θ value	1.41344e-53 (rank : 7)	NC score	0.841000 (rank : 8)
Query Neighborhood Hits	17	Target Neighborhood Hits	113	Shared Neighborhood Hits	10
SwissProt Accessions	O43909, O00225	Gene names	EXTL3, EXTL1L, EXTR1, KIAA0519
Domain Architecture
Description	Exostosin-like 3 (EC 2.4.1.223) (Glucuronyl-galactosyl-proteoglycan 4- alpha-N-acetylglucosaminyltransferase) (Putative tumor suppressor protein EXTL3) (Multiple exostosis-like protein 3) (Hereditary multiple exostoses gene isolog) (EXT-related protein 1).

EXTL3_MOUSE
θ value	1.84601e-53 (rank : 8)	NC score	0.848502 (rank : 7)
Query Neighborhood Hits	17	Target Neighborhood Hits	108	Shared Neighborhood Hits	10
SwissProt Accessions	Q9WVL6	Gene names	Extl3
Domain Architecture
Description	Exostosin-like 3 (EC 2.4.1.-) (Multiple exostosis-like protein 3).

EXTL2_MOUSE
θ value	1.99067e-23 (rank : 9)	NC score	0.792929 (rank : 9)
Query Neighborhood Hits	17	Target Neighborhood Hits	11	Shared Neighborhood Hits	10
SwissProt Accessions	Q9ES89, Q505Q8, Q9CX90	Gene names	Extl2, Extr2
Domain Architecture
Description	Exostosin-like 2 (EC 2.4.1.223) (Glucuronyl-galactosyl-proteoglycan 4- alpha-N-acetylglucosaminyltransferase) (Alpha-1,4-N- acetylhexosaminyltransferase EXTL2) (Alpha-GalNAcT EXTL2) (EXT-related protein 2).

EXTL2_HUMAN
θ value	7.56453e-23 (rank : 10)	NC score	0.790240 (rank : 10)
Query Neighborhood Hits	17	Target Neighborhood Hits	15	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UBQ6	Gene names	EXTL2, EXTR2
Domain Architecture	No domain graphic available
Description	Exostosin-like 2 (EC 2.4.1.223) (Glucuronyl-galactosyl-proteoglycan 4- alpha-N-acetylglucosaminyltransferase) (Alpha-1,4-N- acetylhexosaminyltransferase EXTL2) (Alpha-GalNAcT EXTL2) (EXT-related protein 2).

CBPA1_HUMAN
θ value	1.81305 (rank : 11)	NC score	0.016064 (rank : 15)
Query Neighborhood Hits	17	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	P15085, Q9BS67	Gene names	CPA1, CPA
Domain Architecture
Description	Carboxypeptidase A1 precursor (EC 3.4.17.1).

ABCA3_MOUSE
θ value	8.99809 (rank : 12)	NC score	0.004406 (rank : 17)
Query Neighborhood Hits	17	Target Neighborhood Hits	107	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R420	Gene names	Abca3
Domain Architecture
Description	ATP-binding cassette sub-family A member 3.

AMZ2_HUMAN
θ value	8.99809 (rank : 13)	NC score	0.013532 (rank : 16)
Query Neighborhood Hits	17	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q86W34, Q5XKF1, Q9NZE2	Gene names	AMZ2
Domain Architecture	No domain graphic available
Description	Archaemetzincin-2 (EC 3.-.-.-) (Archeobacterial metalloproteinase-like protein 2).

DCTN4_HUMAN
θ value	8.99809 (rank : 14)	NC score	0.019407 (rank : 12)
Query Neighborhood Hits	17	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UJW0, Q8TAN8	Gene names	DCTN4
Domain Architecture	No domain graphic available
Description	Dynactin subunit 4 (Dynactin subunit p62).

DCTN4_MOUSE
θ value	8.99809 (rank : 15)	NC score	0.019414 (rank : 11)
Query Neighborhood Hits	17	Target Neighborhood Hits	20	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CBY8, Q923A0, Q9D4X0	Gene names	Dctn4
Domain Architecture	No domain graphic available
Description	Dynactin subunit 4 (Dynactin subunit p62).

K0196_HUMAN
θ value	8.99809 (rank : 16)	NC score	0.017351 (rank : 13)
Query Neighborhood Hits	17	Target Neighborhood Hits	28	Shared Neighborhood Hits	4
SwissProt Accessions	Q12768, Q3KQX5, Q8TBQ2	Gene names	KIAA0196
Domain Architecture	No domain graphic available
Description	Protein KIAA0196.

K0196_MOUSE
θ value	8.99809 (rank : 17)	NC score	0.017272 (rank : 14)
Query Neighborhood Hits	17	Target Neighborhood Hits	36	Shared Neighborhood Hits	4
SwissProt Accessions	Q8C2E7, Q8BGY1, Q8K2J2	Gene names	Kiaa0196
Domain Architecture	No domain graphic available
Description	Protein KIAA0196.

Hits sorted by NC score

EXT1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	17	Target Neighborhood Hits	17	Shared Neighborhood Hits	17
SwissProt Accessions	Q16394, Q9BVI9	Gene names	EXT1
Domain Architecture
Description	Exostosin-1 (EC 2.4.1.224) (EC 2.4.1.225) (Glucuronosyl-N- acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4- alpha-N-acetylglucosaminyltransferase) (Putative tumor suppressor protein EXT1) (Multiple exostoses protein 1).

EXT1_MOUSE
NC score	0.999916 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	17	Target Neighborhood Hits	18	Shared Neighborhood Hits	17
SwissProt Accessions	P97464, Q61546	Gene names	Ext1
Domain Architecture
Description	Exostosin-1 (EC 2.4.1.224) (EC 2.4.1.225) (Glucuronosyl-N- acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4- alpha-N-acetylglucosaminyltransferase) (Multiple exostoses protein 1 homolog).

EXTL1_HUMAN
NC score	0.975747 (rank : 3)	θ value	7.04359e-154 (rank : 3)
Query Neighborhood Hits	17	Target Neighborhood Hits	18	Shared Neighborhood Hits	10
SwissProt Accessions	Q92935, Q6GSC1	Gene names	EXTL1, EXTL
Domain Architecture
Description	Exostosin-like 1 (EC 2.4.1.224) (Glucuronosyl-N-acetylglucosaminyl- proteoglycan 4-alpha-N-acetylglucosaminyltransferase) (Exostosin-L) (Multiple exostosis-like protein).

EXTL1_MOUSE
NC score	0.973938 (rank : 4)	θ value	1.62381e-150 (rank : 4)
Query Neighborhood Hits	17	Target Neighborhood Hits	26	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JKV7	Gene names	Extl1
Domain Architecture
Description	Exostosin-like 1 (EC 2.4.1.224) (Glucuronosyl-N-acetylglucosaminyl- proteoglycan 4-alpha-N-acetylglucosaminyltransferase) (Exostosin-L) (Multiple exostosis-like protein).

EXT2_HUMAN
NC score	0.947409 (rank : 5)	θ value	1.8752e-114 (rank : 5)
Query Neighborhood Hits	17	Target Neighborhood Hits	20	Shared Neighborhood Hits	10
SwissProt Accessions	Q93063, O15288	Gene names	EXT2
Domain Architecture
Description	Exostosin-2 (EC 2.4.1.224) (EC 2.4.1.225) (Glucuronosyl-N- acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4- alpha-N-acetylglucosaminyltransferase) (Putative tumor suppressor protein EXT2) (Multiple exostoses protein 2).

EXT2_MOUSE
NC score	0.947188 (rank : 6)	θ value	1.02895e-112 (rank : 6)
Query Neighborhood Hits	17	Target Neighborhood Hits	17	Shared Neighborhood Hits	10
SwissProt Accessions	P70428, P70395, Q923D6	Gene names	Ext2
Domain Architecture
Description	Exostosin-2 (EC 2.4.1.224) (EC 2.4.1.225) (Glucuronosyl-N- acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4- alpha-N-acetylglucosaminyltransferase) (Multiple exostoses protein 2 homolog).

EXTL3_MOUSE
NC score	0.848502 (rank : 7)	θ value	1.84601e-53 (rank : 8)
Query Neighborhood Hits	17	Target Neighborhood Hits	108	Shared Neighborhood Hits	10
SwissProt Accessions	Q9WVL6	Gene names	Extl3
Domain Architecture
Description	Exostosin-like 3 (EC 2.4.1.-) (Multiple exostosis-like protein 3).

EXTL3_HUMAN
NC score	0.841000 (rank : 8)	θ value	1.41344e-53 (rank : 7)
Query Neighborhood Hits	17	Target Neighborhood Hits	113	Shared Neighborhood Hits	10
SwissProt Accessions	O43909, O00225	Gene names	EXTL3, EXTL1L, EXTR1, KIAA0519
Domain Architecture
Description	Exostosin-like 3 (EC 2.4.1.223) (Glucuronyl-galactosyl-proteoglycan 4- alpha-N-acetylglucosaminyltransferase) (Putative tumor suppressor protein EXTL3) (Multiple exostosis-like protein 3) (Hereditary multiple exostoses gene isolog) (EXT-related protein 1).

EXTL2_MOUSE
NC score	0.792929 (rank : 9)	θ value	1.99067e-23 (rank : 9)
Query Neighborhood Hits	17	Target Neighborhood Hits	11	Shared Neighborhood Hits	10
SwissProt Accessions	Q9ES89, Q505Q8, Q9CX90	Gene names	Extl2, Extr2
Domain Architecture
Description	Exostosin-like 2 (EC 2.4.1.223) (Glucuronyl-galactosyl-proteoglycan 4- alpha-N-acetylglucosaminyltransferase) (Alpha-1,4-N- acetylhexosaminyltransferase EXTL2) (Alpha-GalNAcT EXTL2) (EXT-related protein 2).

EXTL2_HUMAN
NC score	0.790240 (rank : 10)	θ value	7.56453e-23 (rank : 10)
Query Neighborhood Hits	17	Target Neighborhood Hits	15	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UBQ6	Gene names	EXTL2, EXTR2
Domain Architecture	No domain graphic available
Description	Exostosin-like 2 (EC 2.4.1.223) (Glucuronyl-galactosyl-proteoglycan 4- alpha-N-acetylglucosaminyltransferase) (Alpha-1,4-N- acetylhexosaminyltransferase EXTL2) (Alpha-GalNAcT EXTL2) (EXT-related protein 2).

DCTN4_MOUSE
NC score	0.019414 (rank : 11)	θ value	8.99809 (rank : 15)
Query Neighborhood Hits	17	Target Neighborhood Hits	20	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CBY8, Q923A0, Q9D4X0	Gene names	Dctn4
Domain Architecture	No domain graphic available
Description	Dynactin subunit 4 (Dynactin subunit p62).

DCTN4_HUMAN
NC score	0.019407 (rank : 12)	θ value	8.99809 (rank : 14)
Query Neighborhood Hits	17	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UJW0, Q8TAN8	Gene names	DCTN4
Domain Architecture	No domain graphic available
Description	Dynactin subunit 4 (Dynactin subunit p62).

K0196_HUMAN
NC score	0.017351 (rank : 13)	θ value	8.99809 (rank : 16)
Query Neighborhood Hits	17	Target Neighborhood Hits	28	Shared Neighborhood Hits	4
SwissProt Accessions	Q12768, Q3KQX5, Q8TBQ2	Gene names	KIAA0196
Domain Architecture	No domain graphic available
Description	Protein KIAA0196.

K0196_MOUSE
NC score	0.017272 (rank : 14)	θ value	8.99809 (rank : 17)
Query Neighborhood Hits	17	Target Neighborhood Hits	36	Shared Neighborhood Hits	4
SwissProt Accessions	Q8C2E7, Q8BGY1, Q8K2J2	Gene names	Kiaa0196
Domain Architecture	No domain graphic available
Description	Protein KIAA0196.

CBPA1_HUMAN
NC score	0.016064 (rank : 15)	θ value	1.81305 (rank : 11)
Query Neighborhood Hits	17	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	P15085, Q9BS67	Gene names	CPA1, CPA
Domain Architecture
Description	Carboxypeptidase A1 precursor (EC 3.4.17.1).

AMZ2_HUMAN
NC score	0.013532 (rank : 16)	θ value	8.99809 (rank : 13)
Query Neighborhood Hits	17	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q86W34, Q5XKF1, Q9NZE2	Gene names	AMZ2
Domain Architecture	No domain graphic available
Description	Archaemetzincin-2 (EC 3.-.-.-) (Archeobacterial metalloproteinase-like protein 2).

ABCA3_MOUSE
NC score	0.004406 (rank : 17)	θ value	8.99809 (rank : 12)
Query Neighborhood Hits	17	Target Neighborhood Hits	107	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R420	Gene names	Abca3
Domain Architecture
Description	ATP-binding cassette sub-family A member 3.