Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : EXT2_MOUSE

For an explanation of this page, click here

EXT2_MOUSE
SwissProt Accessions	P70428, P70395, Q923D6	Gene names	Ext2
Domain Architecture
Description	Exostosin-2 (EC 2.4.1.224) (EC 2.4.1.225) (Glucuronosyl-N- acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4- alpha-N-acetylglucosaminyltransferase) (Multiple exostoses protein 2 homolog).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

EXT2_HUMAN
θ value	0 (rank : 1)	NC score	0.999687 (rank : 2)
Query Neighborhood Hits	17	Target Neighborhood Hits	20	Shared Neighborhood Hits	15
SwissProt Accessions	Q93063, O15288	Gene names	EXT2
Domain Architecture
Description	Exostosin-2 (EC 2.4.1.224) (EC 2.4.1.225) (Glucuronosyl-N- acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4- alpha-N-acetylglucosaminyltransferase) (Putative tumor suppressor protein EXT2) (Multiple exostoses protein 2).

EXT2_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	17	Target Neighborhood Hits	17	Shared Neighborhood Hits	17
SwissProt Accessions	P70428, P70395, Q923D6	Gene names	Ext2
Domain Architecture
Description	Exostosin-2 (EC 2.4.1.224) (EC 2.4.1.225) (Glucuronosyl-N- acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4- alpha-N-acetylglucosaminyltransferase) (Multiple exostoses protein 2 homolog).

EXT1_MOUSE
θ value	6.03229e-113 (rank : 3)	NC score	0.947270 (rank : 3)
Query Neighborhood Hits	17	Target Neighborhood Hits	18	Shared Neighborhood Hits	10
SwissProt Accessions	P97464, Q61546	Gene names	Ext1
Domain Architecture
Description	Exostosin-1 (EC 2.4.1.224) (EC 2.4.1.225) (Glucuronosyl-N- acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4- alpha-N-acetylglucosaminyltransferase) (Multiple exostoses protein 1 homolog).

EXT1_HUMAN
θ value	1.02895e-112 (rank : 4)	NC score	0.947188 (rank : 4)
Query Neighborhood Hits	17	Target Neighborhood Hits	17	Shared Neighborhood Hits	10
SwissProt Accessions	Q16394, Q9BVI9	Gene names	EXT1
Domain Architecture
Description	Exostosin-1 (EC 2.4.1.224) (EC 2.4.1.225) (Glucuronosyl-N- acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4- alpha-N-acetylglucosaminyltransferase) (Putative tumor suppressor protein EXT1) (Multiple exostoses protein 1).

EXTL1_HUMAN
θ value	6.52014e-75 (rank : 5)	NC score	0.922791 (rank : 5)
Query Neighborhood Hits	17	Target Neighborhood Hits	18	Shared Neighborhood Hits	10
SwissProt Accessions	Q92935, Q6GSC1	Gene names	EXTL1, EXTL
Domain Architecture
Description	Exostosin-like 1 (EC 2.4.1.224) (Glucuronosyl-N-acetylglucosaminyl- proteoglycan 4-alpha-N-acetylglucosaminyltransferase) (Exostosin-L) (Multiple exostosis-like protein).

EXTL1_MOUSE
θ value	6.10265e-73 (rank : 6)	NC score	0.922116 (rank : 6)
Query Neighborhood Hits	17	Target Neighborhood Hits	26	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JKV7	Gene names	Extl1
Domain Architecture
Description	Exostosin-like 1 (EC 2.4.1.224) (Glucuronosyl-N-acetylglucosaminyl- proteoglycan 4-alpha-N-acetylglucosaminyltransferase) (Exostosin-L) (Multiple exostosis-like protein).

EXTL3_HUMAN
θ value	6.7473e-72 (rank : 7)	NC score	0.880045 (rank : 8)
Query Neighborhood Hits	17	Target Neighborhood Hits	113	Shared Neighborhood Hits	10
SwissProt Accessions	O43909, O00225	Gene names	EXTL3, EXTL1L, EXTR1, KIAA0519
Domain Architecture
Description	Exostosin-like 3 (EC 2.4.1.223) (Glucuronyl-galactosyl-proteoglycan 4- alpha-N-acetylglucosaminyltransferase) (Putative tumor suppressor protein EXTL3) (Multiple exostosis-like protein 3) (Hereditary multiple exostoses gene isolog) (EXT-related protein 1).

EXTL3_MOUSE
θ value	6.7473e-72 (rank : 8)	NC score	0.883948 (rank : 7)
Query Neighborhood Hits	17	Target Neighborhood Hits	108	Shared Neighborhood Hits	10
SwissProt Accessions	Q9WVL6	Gene names	Extl3
Domain Architecture
Description	Exostosin-like 3 (EC 2.4.1.-) (Multiple exostosis-like protein 3).

EXTL2_MOUSE
θ value	7.29293e-34 (rank : 9)	NC score	0.844420 (rank : 9)
Query Neighborhood Hits	17	Target Neighborhood Hits	11	Shared Neighborhood Hits	10
SwissProt Accessions	Q9ES89, Q505Q8, Q9CX90	Gene names	Extl2, Extr2
Domain Architecture
Description	Exostosin-like 2 (EC 2.4.1.223) (Glucuronyl-galactosyl-proteoglycan 4- alpha-N-acetylglucosaminyltransferase) (Alpha-1,4-N- acetylhexosaminyltransferase EXTL2) (Alpha-GalNAcT EXTL2) (EXT-related protein 2).

EXTL2_HUMAN
θ value	1.79631e-32 (rank : 10)	NC score	0.840704 (rank : 10)
Query Neighborhood Hits	17	Target Neighborhood Hits	15	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UBQ6	Gene names	EXTL2, EXTR2
Domain Architecture	No domain graphic available
Description	Exostosin-like 2 (EC 2.4.1.223) (Glucuronyl-galactosyl-proteoglycan 4- alpha-N-acetylglucosaminyltransferase) (Alpha-1,4-N- acetylhexosaminyltransferase EXTL2) (Alpha-GalNAcT EXTL2) (EXT-related protein 2).

HUG1_HUMAN
θ value	1.81305 (rank : 11)	NC score	0.053685 (rank : 11)
Query Neighborhood Hits	17	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	O75698	Gene names	HUG1, C10orf1
Domain Architecture	No domain graphic available
Description	Protein HUG-1 (HOX11 upstream gene 1 protein).

DEN2C_MOUSE
θ value	3.0926 (rank : 12)	NC score	0.013132 (rank : 14)
Query Neighborhood Hits	17	Target Neighborhood Hits	45	Shared Neighborhood Hits	3
SwissProt Accessions	Q6P9P8, Q3T9X2, Q3UV30, Q80V46	Gene names	Dennd2c
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 2C.

GALM_MOUSE
θ value	6.88961 (rank : 13)	NC score	0.020130 (rank : 12)
Query Neighborhood Hits	17	Target Neighborhood Hits	4	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K157	Gene names	Galm
Domain Architecture	No domain graphic available
Description	Aldose 1-epimerase (EC 5.1.3.3) (Galactose mutarotase).

HPS4_HUMAN
θ value	6.88961 (rank : 14)	NC score	0.018599 (rank : 13)
Query Neighborhood Hits	17	Target Neighborhood Hits	43	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NQG7, Q5H8V6, Q96LX6, Q9BY93, Q9UH37, Q9UH38	Gene names	HPS4, KIAA1667
Domain Architecture	No domain graphic available
Description	Hermansky-Pudlak syndrome 4 protein (Light-ear protein homolog).

ADAM8_HUMAN
θ value	8.99809 (rank : 15)	NC score	0.004930 (rank : 16)
Query Neighborhood Hits	17	Target Neighborhood Hits	327	Shared Neighborhood Hits	4
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

LRP4_MOUSE
θ value	8.99809 (rank : 16)	NC score	0.001673 (rank : 17)
Query Neighborhood Hits	17	Target Neighborhood Hits	351	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).

PI4KA_HUMAN
θ value	8.99809 (rank : 17)	NC score	0.006656 (rank : 15)
Query Neighborhood Hits	17	Target Neighborhood Hits	53	Shared Neighborhood Hits	2
SwissProt Accessions	P42356, Q7Z625, Q9UPG2	Gene names	PIK4CA, PIK4
Domain Architecture
Description	Phosphatidylinositol 4-kinase alpha (EC 2.7.1.67) (PI4-kinase alpha) (PtdIns-4-kinase alpha) (PI4K-alpha).

Hits sorted by NC score

EXT2_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	17	Target Neighborhood Hits	17	Shared Neighborhood Hits	17
SwissProt Accessions	P70428, P70395, Q923D6	Gene names	Ext2
Domain Architecture
Description	Exostosin-2 (EC 2.4.1.224) (EC 2.4.1.225) (Glucuronosyl-N- acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4- alpha-N-acetylglucosaminyltransferase) (Multiple exostoses protein 2 homolog).

EXT2_HUMAN
NC score	0.999687 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	17	Target Neighborhood Hits	20	Shared Neighborhood Hits	15
SwissProt Accessions	Q93063, O15288	Gene names	EXT2
Domain Architecture
Description	Exostosin-2 (EC 2.4.1.224) (EC 2.4.1.225) (Glucuronosyl-N- acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4- alpha-N-acetylglucosaminyltransferase) (Putative tumor suppressor protein EXT2) (Multiple exostoses protein 2).

EXT1_MOUSE
NC score	0.947270 (rank : 3)	θ value	6.03229e-113 (rank : 3)
Query Neighborhood Hits	17	Target Neighborhood Hits	18	Shared Neighborhood Hits	10
SwissProt Accessions	P97464, Q61546	Gene names	Ext1
Domain Architecture
Description	Exostosin-1 (EC 2.4.1.224) (EC 2.4.1.225) (Glucuronosyl-N- acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4- alpha-N-acetylglucosaminyltransferase) (Multiple exostoses protein 1 homolog).

EXT1_HUMAN
NC score	0.947188 (rank : 4)	θ value	1.02895e-112 (rank : 4)
Query Neighborhood Hits	17	Target Neighborhood Hits	17	Shared Neighborhood Hits	10
SwissProt Accessions	Q16394, Q9BVI9	Gene names	EXT1
Domain Architecture
Description	Exostosin-1 (EC 2.4.1.224) (EC 2.4.1.225) (Glucuronosyl-N- acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4- alpha-N-acetylglucosaminyltransferase) (Putative tumor suppressor protein EXT1) (Multiple exostoses protein 1).

EXTL1_HUMAN
NC score	0.922791 (rank : 5)	θ value	6.52014e-75 (rank : 5)
Query Neighborhood Hits	17	Target Neighborhood Hits	18	Shared Neighborhood Hits	10
SwissProt Accessions	Q92935, Q6GSC1	Gene names	EXTL1, EXTL
Domain Architecture
Description	Exostosin-like 1 (EC 2.4.1.224) (Glucuronosyl-N-acetylglucosaminyl- proteoglycan 4-alpha-N-acetylglucosaminyltransferase) (Exostosin-L) (Multiple exostosis-like protein).

EXTL1_MOUSE
NC score	0.922116 (rank : 6)	θ value	6.10265e-73 (rank : 6)
Query Neighborhood Hits	17	Target Neighborhood Hits	26	Shared Neighborhood Hits	10
SwissProt Accessions	Q9JKV7	Gene names	Extl1
Domain Architecture
Description	Exostosin-like 1 (EC 2.4.1.224) (Glucuronosyl-N-acetylglucosaminyl- proteoglycan 4-alpha-N-acetylglucosaminyltransferase) (Exostosin-L) (Multiple exostosis-like protein).

EXTL3_MOUSE
NC score	0.883948 (rank : 7)	θ value	6.7473e-72 (rank : 8)
Query Neighborhood Hits	17	Target Neighborhood Hits	108	Shared Neighborhood Hits	10
SwissProt Accessions	Q9WVL6	Gene names	Extl3
Domain Architecture
Description	Exostosin-like 3 (EC 2.4.1.-) (Multiple exostosis-like protein 3).

EXTL3_HUMAN
NC score	0.880045 (rank : 8)	θ value	6.7473e-72 (rank : 7)
Query Neighborhood Hits	17	Target Neighborhood Hits	113	Shared Neighborhood Hits	10
SwissProt Accessions	O43909, O00225	Gene names	EXTL3, EXTL1L, EXTR1, KIAA0519
Domain Architecture
Description	Exostosin-like 3 (EC 2.4.1.223) (Glucuronyl-galactosyl-proteoglycan 4- alpha-N-acetylglucosaminyltransferase) (Putative tumor suppressor protein EXTL3) (Multiple exostosis-like protein 3) (Hereditary multiple exostoses gene isolog) (EXT-related protein 1).

EXTL2_MOUSE
NC score	0.844420 (rank : 9)	θ value	7.29293e-34 (rank : 9)
Query Neighborhood Hits	17	Target Neighborhood Hits	11	Shared Neighborhood Hits	10
SwissProt Accessions	Q9ES89, Q505Q8, Q9CX90	Gene names	Extl2, Extr2
Domain Architecture
Description	Exostosin-like 2 (EC 2.4.1.223) (Glucuronyl-galactosyl-proteoglycan 4- alpha-N-acetylglucosaminyltransferase) (Alpha-1,4-N- acetylhexosaminyltransferase EXTL2) (Alpha-GalNAcT EXTL2) (EXT-related protein 2).

EXTL2_HUMAN
NC score	0.840704 (rank : 10)	θ value	1.79631e-32 (rank : 10)
Query Neighborhood Hits	17	Target Neighborhood Hits	15	Shared Neighborhood Hits	10
SwissProt Accessions	Q9UBQ6	Gene names	EXTL2, EXTR2
Domain Architecture	No domain graphic available
Description	Exostosin-like 2 (EC 2.4.1.223) (Glucuronyl-galactosyl-proteoglycan 4- alpha-N-acetylglucosaminyltransferase) (Alpha-1,4-N- acetylhexosaminyltransferase EXTL2) (Alpha-GalNAcT EXTL2) (EXT-related protein 2).

HUG1_HUMAN
NC score	0.053685 (rank : 11)	θ value	1.81305 (rank : 11)
Query Neighborhood Hits	17	Target Neighborhood Hits	11	Shared Neighborhood Hits	3
SwissProt Accessions	O75698	Gene names	HUG1, C10orf1
Domain Architecture	No domain graphic available
Description	Protein HUG-1 (HOX11 upstream gene 1 protein).

GALM_MOUSE
NC score	0.020130 (rank : 12)	θ value	6.88961 (rank : 13)
Query Neighborhood Hits	17	Target Neighborhood Hits	4	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K157	Gene names	Galm
Domain Architecture	No domain graphic available
Description	Aldose 1-epimerase (EC 5.1.3.3) (Galactose mutarotase).

HPS4_HUMAN
NC score	0.018599 (rank : 13)	θ value	6.88961 (rank : 14)
Query Neighborhood Hits	17	Target Neighborhood Hits	43	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NQG7, Q5H8V6, Q96LX6, Q9BY93, Q9UH37, Q9UH38	Gene names	HPS4, KIAA1667
Domain Architecture	No domain graphic available
Description	Hermansky-Pudlak syndrome 4 protein (Light-ear protein homolog).

DEN2C_MOUSE
NC score	0.013132 (rank : 14)	θ value	3.0926 (rank : 12)
Query Neighborhood Hits	17	Target Neighborhood Hits	45	Shared Neighborhood Hits	3
SwissProt Accessions	Q6P9P8, Q3T9X2, Q3UV30, Q80V46	Gene names	Dennd2c
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 2C.

PI4KA_HUMAN
NC score	0.006656 (rank : 15)	θ value	8.99809 (rank : 17)
Query Neighborhood Hits	17	Target Neighborhood Hits	53	Shared Neighborhood Hits	2
SwissProt Accessions	P42356, Q7Z625, Q9UPG2	Gene names	PIK4CA, PIK4
Domain Architecture
Description	Phosphatidylinositol 4-kinase alpha (EC 2.7.1.67) (PI4-kinase alpha) (PtdIns-4-kinase alpha) (PI4K-alpha).

ADAM8_HUMAN
NC score	0.004930 (rank : 16)	θ value	8.99809 (rank : 15)
Query Neighborhood Hits	17	Target Neighborhood Hits	327	Shared Neighborhood Hits	4
SwissProt Accessions	P78325	Gene names	ADAM8, MS2
Domain Architecture
Description	ADAM 8 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 8) (Cell surface antigen MS2) (CD156a antigen) (CD156).

LRP4_MOUSE
NC score	0.001673 (rank : 17)	θ value	8.99809 (rank : 16)
Query Neighborhood Hits	17	Target Neighborhood Hits	351	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VI56, Q8BPX5, Q8CBB3, Q8CCP5	Gene names	Lrp4, Kiaa0816
Domain Architecture
Description	Low-density lipoprotein receptor-related protein 4 precursor (LDLR dan).