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Network neighborhood for query Sequence : ALMS1_MOUSE

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ALMS1_MOUSE
SwissProt Accessions	Q8K4E0, Q6A084, Q8C9N9	Gene names	Alms1, Kiaa0328
Domain Architecture	No domain graphic available
Description	Alstrom syndrome protein 1 homolog.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ALMS1_HUMAN
θ value	0 (rank : 1)	NC score	0.895643 (rank : 2)
Query Neighborhood Hits	181	Target Neighborhood Hits	356	Shared Neighborhood Hits	37
SwissProt Accessions	Q8TCU4, Q53S05, Q580Q8, Q86VP9, Q9Y4G4	Gene names	ALMS1, KIAA0328
Domain Architecture	No domain graphic available
Description	Alstrom syndrome protein 1.

ALMS1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	181	Target Neighborhood Hits	181	Shared Neighborhood Hits	181
SwissProt Accessions	Q8K4E0, Q6A084, Q8C9N9	Gene names	Alms1, Kiaa0328
Domain Architecture	No domain graphic available
Description	Alstrom syndrome protein 1 homolog.

SRRM2_HUMAN
θ value	5.44631e-05 (rank : 3)	NC score	0.128256 (rank : 3)
Query Neighborhood Hits	181	Target Neighborhood Hits	1296	Shared Neighborhood Hits	58
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

NACAM_MOUSE
θ value	9.29e-05 (rank : 4)	NC score	0.123368 (rank : 4)
Query Neighborhood Hits	181	Target Neighborhood Hits	1866	Shared Neighborhood Hits	86
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

AFF4_MOUSE
θ value	0.00509761 (rank : 5)	NC score	0.073329 (rank : 12)
Query Neighborhood Hits	181	Target Neighborhood Hits	581	Shared Neighborhood Hits	32
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

ANK3_HUMAN
θ value	0.00509761 (rank : 6)	NC score	0.027805 (rank : 90)
Query Neighborhood Hits	181	Target Neighborhood Hits	853	Shared Neighborhood Hits	28
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

NFRKB_HUMAN
θ value	0.0148317 (rank : 7)	NC score	0.076643 (rank : 11)
Query Neighborhood Hits	181	Target Neighborhood Hits	211	Shared Neighborhood Hits	19
SwissProt Accessions	Q6P4R8, Q12869, Q15312, Q9H048	Gene names	NFRKB
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

CBP_MOUSE
θ value	0.0431538 (rank : 8)	NC score	0.079699 (rank : 9)
Query Neighborhood Hits	181	Target Neighborhood Hits	1051	Shared Neighborhood Hits	61
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

SSH2_MOUSE
θ value	0.0431538 (rank : 9)	NC score	0.041726 (rank : 48)
Query Neighborhood Hits	181	Target Neighborhood Hits	119	Shared Neighborhood Hits	9
SwissProt Accessions	Q5SW75, Q3TDK8, Q3TYP8, Q3U2K3, Q5F268, Q5SW74, Q69ZC3, Q76I78	Gene names	Ssh2, Kiaa1725, Ssh2l
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 2 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-2L) (mSSH-2L).

KCNQ2_MOUSE
θ value	0.0736092 (rank : 10)	NC score	0.029255 (rank : 85)
Query Neighborhood Hits	181	Target Neighborhood Hits	163	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Z351, Q8R498, Q9QWN9, Q9Z342, Q9Z343, Q9Z344, Q9Z345, Q9Z346, Q9Z347, Q9Z348, Q9Z349, Q9Z350	Gene names	Kcnq2, Kqt2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Potassium channel subunit alpha KvLQT2) (KQT-like 2).

AKA12_HUMAN
θ value	0.0961366 (rank : 11)	NC score	0.069852 (rank : 13)
Query Neighborhood Hits	181	Target Neighborhood Hits	825	Shared Neighborhood Hits	44
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

EP300_HUMAN
θ value	0.163984 (rank : 12)	NC score	0.094940 (rank : 6)
Query Neighborhood Hits	181	Target Neighborhood Hits	821	Shared Neighborhood Hits	45
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

CBP_HUMAN
θ value	0.21417 (rank : 13)	NC score	0.084270 (rank : 8)
Query Neighborhood Hits	181	Target Neighborhood Hits	941	Shared Neighborhood Hits	57
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

MAP4_HUMAN
θ value	0.279714 (rank : 14)	NC score	0.068674 (rank : 14)
Query Neighborhood Hits	181	Target Neighborhood Hits	428	Shared Neighborhood Hits	38
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

PDZD2_HUMAN
θ value	0.279714 (rank : 15)	NC score	0.048744 (rank : 31)
Query Neighborhood Hits	181	Target Neighborhood Hits	772	Shared Neighborhood Hits	48
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

RBMX2_MOUSE
θ value	0.279714 (rank : 16)	NC score	0.030407 (rank : 79)
Query Neighborhood Hits	181	Target Neighborhood Hits	287	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R0F5, Q3TI42	Gene names	Rbmx2
Domain Architecture
Description	RNA-binding motif protein, X-linked 2.

VPS72_HUMAN
θ value	0.279714 (rank : 17)	NC score	0.067696 (rank : 15)
Query Neighborhood Hits	181	Target Neighborhood Hits	274	Shared Neighborhood Hits	17
SwissProt Accessions	Q15906, Q53GJ2, Q5U0R4	Gene names	VPS72, TCFL1, YL1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

VPS72_MOUSE
θ value	0.365318 (rank : 18)	NC score	0.065519 (rank : 17)
Query Neighborhood Hits	181	Target Neighborhood Hits	286	Shared Neighborhood Hits	15
SwissProt Accessions	Q62481, Q3U2N4, Q810A9, Q99K81	Gene names	Vps72, Tcfl1, Yl1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

ARI1A_HUMAN
θ value	0.47712 (rank : 19)	NC score	0.063302 (rank : 19)
Query Neighborhood Hits	181	Target Neighborhood Hits	787	Shared Neighborhood Hits	45
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

K0146_HUMAN
θ value	0.47712 (rank : 20)	NC score	0.044151 (rank : 43)
Query Neighborhood Hits	181	Target Neighborhood Hits	48	Shared Neighborhood Hits	3
SwissProt Accessions	Q14159, Q96BI5	Gene names	KIAA0146
Domain Architecture	No domain graphic available
Description	Protein KIAA0146.

MAGC1_HUMAN
θ value	0.47712 (rank : 21)	NC score	0.038366 (rank : 60)
Query Neighborhood Hits	181	Target Neighborhood Hits	431	Shared Neighborhood Hits	34
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

MAML1_HUMAN
θ value	0.47712 (rank : 22)	NC score	0.045694 (rank : 40)
Query Neighborhood Hits	181	Target Neighborhood Hits	228	Shared Neighborhood Hits	26
SwissProt Accessions	Q92585, Q9NZ12	Gene names	MAML1, KIAA0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

TMUB1_HUMAN
θ value	0.47712 (rank : 23)	NC score	0.050237 (rank : 30)
Query Neighborhood Hits	181	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BVT8	Gene names	TMUB1, C7orf21
Domain Architecture
Description	Transmembrane and ubiquitin-like domain-containing protein 1 (Ubiquitin-like protein SB144).

CJ084_HUMAN
θ value	0.62314 (rank : 24)	NC score	0.054316 (rank : 23)
Query Neighborhood Hits	181	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H8W3, Q9H5V5	Gene names	C10orf84
Domain Architecture	No domain graphic available
Description	Protein C10orf84.

KIF17_MOUSE
θ value	0.62314 (rank : 25)	NC score	0.017469 (rank : 122)
Query Neighborhood Hits	181	Target Neighborhood Hits	452	Shared Neighborhood Hits	16
SwissProt Accessions	Q99PW8	Gene names	Kif17
Domain Architecture
Description	Kinesin-like protein KIF17 (MmKIF17).

SRRM2_MOUSE
θ value	0.62314 (rank : 26)	NC score	0.098836 (rank : 5)
Query Neighborhood Hits	181	Target Neighborhood Hits	1470	Shared Neighborhood Hits	75
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

TPR_HUMAN
θ value	0.62314 (rank : 27)	NC score	0.019198 (rank : 115)
Query Neighborhood Hits	181	Target Neighborhood Hits	1921	Shared Neighborhood Hits	44
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

XKR5_HUMAN
θ value	0.62314 (rank : 28)	NC score	0.043809 (rank : 46)
Query Neighborhood Hits	181	Target Neighborhood Hits	54	Shared Neighborhood Hits	12
SwissProt Accessions	Q6UX68, Q5GH74	Gene names	XKR5, XRG5
Domain Architecture	No domain graphic available
Description	XK-related protein 5.

DSCL1_HUMAN
θ value	0.813845 (rank : 29)	NC score	0.011836 (rank : 150)
Query Neighborhood Hits	181	Target Neighborhood Hits	589	Shared Neighborhood Hits	15
SwissProt Accessions	Q8TD84, Q76MU9, Q8IZY3, Q8IZY4, Q8WXU7, Q9ULT7	Gene names	DSCAML1, DSCAM2, KIAA1132
Domain Architecture	No domain graphic available
Description	Down syndrome cell adhesion molecule-like protein 1 precursor (Down syndrome cell adhesion molecule 2).

FGD1_MOUSE
θ value	0.813845 (rank : 30)	NC score	0.021639 (rank : 107)
Query Neighborhood Hits	181	Target Neighborhood Hits	387	Shared Neighborhood Hits	20
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

TFAM_MOUSE
θ value	0.813845 (rank : 31)	NC score	0.078768 (rank : 10)
Query Neighborhood Hits	181	Target Neighborhood Hits	93	Shared Neighborhood Hits	10
SwissProt Accessions	P40630, P97894, P97906, Q543I8, Q9DBM9	Gene names	Tfam, Hmgts
Domain Architecture
Description	Transcription factor A, mitochondrial precursor (mtTFA) (Testis- specific high mobility group protein) (TS-HMG).

ATX7_HUMAN
θ value	1.06291 (rank : 32)	NC score	0.042162 (rank : 47)
Query Neighborhood Hits	181	Target Neighborhood Hits	351	Shared Neighborhood Hits	24
SwissProt Accessions	O15265, O75328, O75329, Q9Y6P8	Gene names	ATXN7, SCA7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein).

FA21C_HUMAN
θ value	1.06291 (rank : 33)	NC score	0.046981 (rank : 35)
Query Neighborhood Hits	181	Target Neighborhood Hits	194	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y4E1, Q5SQU4, Q5SQU5, Q7L521, Q9UG79	Gene names	FAM21C, KIAA0592
Domain Architecture	No domain graphic available
Description	Protein FAM21C.

HNRPC_MOUSE
θ value	1.06291 (rank : 34)	NC score	0.029638 (rank : 84)
Query Neighborhood Hits	181	Target Neighborhood Hits	190	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Z204, Q3TLB5, Q501Q3, Q8C2G5, Q99KE2, Q9CQT3, Q9CY83	Gene names	Hnrpc, Hnrnpc
Domain Architecture
Description	Heterogeneous nuclear ribonucleoproteins C1/C2 (hnRNP C1 / hnRNP C2).

HXA11_HUMAN
θ value	1.06291 (rank : 35)	NC score	0.018750 (rank : 116)
Query Neighborhood Hits	181	Target Neighborhood Hits	334	Shared Neighborhood Hits	4
SwissProt Accessions	P31270	Gene names	HOXA11, HOX1I
Domain Architecture
Description	Homeobox protein Hox-A11 (Hox-1I).

HXA11_MOUSE
θ value	1.06291 (rank : 36)	NC score	0.014956 (rank : 130)
Query Neighborhood Hits	181	Target Neighborhood Hits	327	Shared Neighborhood Hits	3
SwissProt Accessions	P31311, Q3V026	Gene names	Hoxa11, Hox-1.9, Hoxa-11
Domain Architecture
Description	Homeobox protein Hox-A11 (Hox-1.9).

PENK_HUMAN
θ value	1.06291 (rank : 37)	NC score	0.038849 (rank : 57)
Query Neighborhood Hits	181	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	P01210	Gene names	PENK
Domain Architecture
Description	Proenkephalin A precursor [Contains: Synenkephalin; Met-enkephalin (Opioid growth factor) (OGF); Met-enkephalin-Arg-Gly-Leu; Leu- enkephalin; Met-enkephalin-Arg-Phe].

PRGC1_HUMAN
θ value	1.06291 (rank : 38)	NC score	0.036254 (rank : 64)
Query Neighborhood Hits	181	Target Neighborhood Hits	157	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UBK2, Q9UN32	Gene names	PPARGC1A, LEM6, PGC1, PGC1A, PPARGC1
Domain Architecture
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PPAR gamma coactivator 1-alpha) (PPARGC-1-alpha) (PGC-1-alpha) (Ligand effect modulator 6).

ST5_MOUSE
θ value	1.06291 (rank : 39)	NC score	0.023102 (rank : 102)
Query Neighborhood Hits	181	Target Neighborhood Hits	126	Shared Neighborhood Hits	10
SwissProt Accessions	Q924W7, Q78H54, Q8K2P3, Q924W8	Gene names	St5, Dennd2b
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity 5 (DENN domain-containing protein 2B).

SYTL2_HUMAN
θ value	1.06291 (rank : 40)	NC score	0.021435 (rank : 108)
Query Neighborhood Hits	181	Target Neighborhood Hits	248	Shared Neighborhood Hits	10
SwissProt Accessions	Q9HCH5, Q2YDA7, Q8ND34, Q96BJ2, Q9H768, Q9NXM1	Gene names	SYTL2, KIAA1597, SLP2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

ZAN_MOUSE
θ value	1.06291 (rank : 41)	NC score	0.041520 (rank : 50)
Query Neighborhood Hits	181	Target Neighborhood Hits	808	Shared Neighborhood Hits	20
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

A4_HUMAN
θ value	1.38821 (rank : 42)	NC score	0.041069 (rank : 52)
Query Neighborhood Hits	181	Target Neighborhood Hits	274	Shared Neighborhood Hits	14
SwissProt Accessions	P05067, P09000, P78438, Q13764, Q13778, Q13793, Q16011, Q16014, Q16019, Q16020, Q9BT38, Q9UCA9, Q9UCB6, Q9UCC8, Q9UCD1, Q9UQ58	Gene names	APP, A4, AD1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 protein precursor (APP) (ABPP) (Alzheimer disease amyloid protein) (Cerebral vascular amyloid peptide) (CVAP) (Protease nexin-II) (PN-II) (APPI) (PreA4) [Contains: Soluble APP-alpha (S-APP- alpha); Soluble APP-beta (S-APP-beta); C99; Beta-amyloid protein 42 (Beta-APP42); Beta-amyloid protein 40 (Beta-APP40); C83; P3(42); P3(40); Gamma-CTF(59) (Gamma-secretase C-terminal fragment 59) (Amyloid intracellular domain 59) (AID(59)); Gamma-CTF(57) (Gamma- secretase C-terminal fragment 57) (Amyloid intracellular domain 57) (AID(57)); Gamma-CTF(50) (Gamma-secretase C-terminal fragment 50) (Amyloid intracellular domain 50) (AID(50)); C31].

APLP2_HUMAN
θ value	1.38821 (rank : 43)	NC score	0.046997 (rank : 34)
Query Neighborhood Hits	181	Target Neighborhood Hits	193	Shared Neighborhood Hits	11
SwissProt Accessions	Q06481	Gene names	APLP2, APPL2
Domain Architecture
Description	Amyloid-like protein 2 precursor (Amyloid protein homolog) (APPH) (CDEI box-binding protein) (CDEBP).

BPAEA_MOUSE
θ value	1.38821 (rank : 44)	NC score	0.013265 (rank : 141)
Query Neighborhood Hits	181	Target Neighborhood Hits	1480	Shared Neighborhood Hits	27
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

ELK3_MOUSE
θ value	1.38821 (rank : 45)	NC score	0.017051 (rank : 125)
Query Neighborhood Hits	181	Target Neighborhood Hits	72	Shared Neighborhood Hits	4
SwissProt Accessions	P41971, P97747, Q62346	Gene names	Elk3, Erp, Net
Domain Architecture
Description	ETS domain-containing protein Elk-3 (ETS-related protein NET) (ETS- related protein ERP).

FMNL_HUMAN
θ value	1.38821 (rank : 46)	NC score	0.028307 (rank : 89)
Query Neighborhood Hits	181	Target Neighborhood Hits	529	Shared Neighborhood Hits	27
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

HUWE1_HUMAN
θ value	1.38821 (rank : 47)	NC score	0.020928 (rank : 110)
Query Neighborhood Hits	181	Target Neighborhood Hits	443	Shared Neighborhood Hits	25
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

MYCB2_HUMAN
θ value	1.38821 (rank : 48)	NC score	0.040286 (rank : 55)
Query Neighborhood Hits	181	Target Neighborhood Hits	390	Shared Neighborhood Hits	19
SwissProt Accessions	O75592, Q5JSX8, Q5VZN6, Q6PIB6, Q9UQ11, Q9Y6E4	Gene names	MYCBP2, KIAA0916, PAM
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

NTHL1_MOUSE
θ value	1.38821 (rank : 49)	NC score	0.045760 (rank : 39)
Query Neighborhood Hits	181	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	O35980	Gene names	Nthl1, Nth1
Domain Architecture
Description	Endonuclease III-like protein 1 (EC 4.2.99.18).

PCLO_MOUSE
θ value	1.38821 (rank : 50)	NC score	0.046922 (rank : 37)
Query Neighborhood Hits	181	Target Neighborhood Hits	2275	Shared Neighborhood Hits	83
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

PDXL2_MOUSE
θ value	1.38821 (rank : 51)	NC score	0.053705 (rank : 26)
Query Neighborhood Hits	181	Target Neighborhood Hits	213	Shared Neighborhood Hits	24
SwissProt Accessions	Q8CAE9, Q8CFW3	Gene names	Podxl2
Domain Architecture	No domain graphic available
Description	Podocalyxin-like protein 2 precursor (Endoglycan).

PHAR2_HUMAN
θ value	1.38821 (rank : 52)	NC score	0.040537 (rank : 54)
Query Neighborhood Hits	181	Target Neighborhood Hits	208	Shared Neighborhood Hits	16
SwissProt Accessions	O75167, Q68DM2	Gene names	PHACTR2, C6orf56, KIAA0680
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 2.

SETB1_MOUSE
θ value	1.38821 (rank : 53)	NC score	0.029786 (rank : 83)
Query Neighborhood Hits	181	Target Neighborhood Hits	150	Shared Neighborhood Hits	13
SwissProt Accessions	O88974, Q922K1	Gene names	Setdb1, Eset
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

TLR2_HUMAN
θ value	1.38821 (rank : 54)	NC score	0.013531 (rank : 139)
Query Neighborhood Hits	181	Target Neighborhood Hits	290	Shared Neighborhood Hits	5
SwissProt Accessions	O60603, O15454, Q8NI00	Gene names	TLR2, TIL4
Domain Architecture
Description	Toll-like receptor 2 precursor (Toll/interleukin 1 receptor-like protein 4) (CD282 antigen).

TREF1_MOUSE
θ value	1.38821 (rank : 55)	NC score	0.023674 (rank : 99)
Query Neighborhood Hits	181	Target Neighborhood Hits	682	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BXJ2, Q6PCQ4, Q80X25, Q810H8, Q8BY31	Gene names	Trerf1
Domain Architecture	No domain graphic available
Description	Transcriptional-regulating factor 1 (Transcriptional-regulating protein 132) (Zinc finger transcription factor TReP-132).

3BP2_MOUSE
θ value	1.81305 (rank : 56)	NC score	0.030837 (rank : 78)
Query Neighborhood Hits	181	Target Neighborhood Hits	142	Shared Neighborhood Hits	9
SwissProt Accessions	Q06649	Gene names	Sh3bp2, 3bp2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

BMP2K_HUMAN
θ value	1.81305 (rank : 57)	NC score	0.010697 (rank : 156)
Query Neighborhood Hits	181	Target Neighborhood Hits	867	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NSY1, O94791, Q8IYF2, Q8N2G7, Q8NHG9, Q9NTG8	Gene names	BMP2K, BIKE
Domain Architecture
Description	BMP-2-inducible protein kinase (EC 2.7.11.1) (BIKe).

CC47_MOUSE
θ value	1.81305 (rank : 58)	NC score	0.030927 (rank : 77)
Query Neighborhood Hits	181	Target Neighborhood Hits	245	Shared Neighborhood Hits	12
SwissProt Accessions	Q9D024, Q3TSB5, Q3V1S7, Q8C5D9, Q920S6	Gene names	Ccdc47, Asp4
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 47 precursor (Adipocyte-specific protein 4).

LR37B_HUMAN
θ value	1.81305 (rank : 59)	NC score	0.025728 (rank : 94)
Query Neighborhood Hits	181	Target Neighborhood Hits	392	Shared Neighborhood Hits	23
SwissProt Accessions	Q96QE4, Q5YKG6	Gene names	LRRC37B
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37B precursor (C66 SLIT-like testicular protein).

MARK2_HUMAN
θ value	1.81305 (rank : 60)	NC score	0.006182 (rank : 178)
Query Neighborhood Hits	181	Target Neighborhood Hits	1056	Shared Neighborhood Hits	26
SwissProt Accessions	Q7KZI7, Q15449, Q15524, Q5XGA3, Q68A18, Q96HB3, Q96RG0	Gene names	MARK2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 2) (ELKL motif kinase) (EMK1) (PAR1 homolog).

PGCA_HUMAN
θ value	1.81305 (rank : 61)	NC score	0.037814 (rank : 61)
Query Neighborhood Hits	181	Target Neighborhood Hits	821	Shared Neighborhood Hits	35
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

PRG4_MOUSE
θ value	1.81305 (rank : 62)	NC score	0.045118 (rank : 42)
Query Neighborhood Hits	181	Target Neighborhood Hits	624	Shared Neighborhood Hits	40
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

T22D2_HUMAN
θ value	1.81305 (rank : 63)	NC score	0.047723 (rank : 32)
Query Neighborhood Hits	181	Target Neighborhood Hits	250	Shared Neighborhood Hits	23
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

ZN551_HUMAN
θ value	1.81305 (rank : 64)	NC score	0.001394 (rank : 187)
Query Neighborhood Hits	181	Target Neighborhood Hits	753	Shared Neighborhood Hits	10
SwissProt Accessions	Q7Z340, P17034, Q8N246, Q9BRY1	Gene names	ZNF551, KOX23
Domain Architecture	No domain graphic available
Description	Zinc finger protein 551 (Zinc finger protein KOX23).

ARID2_HUMAN
θ value	2.36792 (rank : 65)	NC score	0.043830 (rank : 45)
Query Neighborhood Hits	181	Target Neighborhood Hits	302	Shared Neighborhood Hits	29
SwissProt Accessions	Q68CP9, Q5EB51, Q645I3, Q6ZRY5, Q7Z3I5, Q86T28, Q96SJ6, Q9HCL5	Gene names	ARID2, KIAA1557
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 2 (ARID domain- containing protein 2) (BRG1-associated factor 200) (BAF200).

CNOT3_HUMAN
θ value	2.36792 (rank : 66)	NC score	0.038676 (rank : 59)
Query Neighborhood Hits	181	Target Neighborhood Hits	425	Shared Neighborhood Hits	23
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

CO7A1_HUMAN
θ value	2.36792 (rank : 67)	NC score	0.014967 (rank : 129)
Query Neighborhood Hits	181	Target Neighborhood Hits	807	Shared Neighborhood Hits	33
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

DCP1A_MOUSE
θ value	2.36792 (rank : 68)	NC score	0.046809 (rank : 38)
Query Neighborhood Hits	181	Target Neighborhood Hits	103	Shared Neighborhood Hits	13
SwissProt Accessions	Q91YD3, Q6NZE3	Gene names	Dcp1a, Mitc1, Smif
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1A (EC 3.-.-.-) (Transcription factor SMIF) (MAD homolog 4-interacting transcription coactivator 1) (Smad4-interacting transcriptional co-activator).

FXL19_HUMAN
θ value	2.36792 (rank : 69)	NC score	0.023541 (rank : 100)
Query Neighborhood Hits	181	Target Neighborhood Hits	147	Shared Neighborhood Hits	8
SwissProt Accessions	Q6PCT2, Q8N789, Q9NT14	Gene names	FBXL19, FBL19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

K2027_MOUSE
θ value	2.36792 (rank : 70)	NC score	0.036045 (rank : 65)
Query Neighborhood Hits	181	Target Neighborhood Hits	106	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BWS5, Q69Z30	Gene names	Kiaa2027
Domain Architecture	No domain graphic available
Description	Protein KIAA2027.

KI67_HUMAN
θ value	2.36792 (rank : 71)	NC score	0.052716 (rank : 27)
Query Neighborhood Hits	181	Target Neighborhood Hits	581	Shared Neighborhood Hits	33
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

MACF1_MOUSE
θ value	2.36792 (rank : 72)	NC score	0.011517 (rank : 152)
Query Neighborhood Hits	181	Target Neighborhood Hits	1313	Shared Neighborhood Hits	28
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

MAFB_MOUSE
θ value	2.36792 (rank : 73)	NC score	0.021235 (rank : 109)
Query Neighborhood Hits	181	Target Neighborhood Hits	92	Shared Neighborhood Hits	5
SwissProt Accessions	P54841	Gene names	Mafb, Krml, Maf1
Domain Architecture
Description	Transcription factor MafB (V-maf musculoaponeurotic fibrosarcoma oncogene homolog B) (Transcription factor MAF1) (Segmentation protein KR) (Kreisler).

MAGE1_HUMAN
θ value	2.36792 (rank : 74)	NC score	0.040686 (rank : 53)
Query Neighborhood Hits	181	Target Neighborhood Hits	1389	Shared Neighborhood Hits	73
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

NCOAT_MOUSE
θ value	2.36792 (rank : 75)	NC score	0.026709 (rank : 93)
Query Neighborhood Hits	181	Target Neighborhood Hits	43	Shared Neighborhood Hits	3
SwissProt Accessions	Q9EQQ9, Q3ULY7, Q6ZQ71, Q8BK05, Q8BTT2, Q8CFX2, Q9CSJ4, Q9CUR7	Gene names	Mgea5, Hexc, Kiaa0679
Domain Architecture	No domain graphic available
Description	Bifunctional protein NCOAT (Nuclear cytoplasmic O-GlcNAcase and acetyltransferase) (Meningioma-expressed antigen 5) [Includes: Beta- hexosaminidase (EC 3.2.1.52) (N-acetyl-beta-glucosaminidase) (Beta-N- acetylhexosaminidase) (Hexosaminidase C) (N-acetyl-beta-D- glucosaminidase) (O-GlcNAcase); Histone acetyltransferase (EC 2.3.1.48) (HAT)].

PDPN_HUMAN
θ value	2.36792 (rank : 76)	NC score	0.050340 (rank : 29)
Query Neighborhood Hits	181	Target Neighborhood Hits	12	Shared Neighborhood Hits	5
SwissProt Accessions	Q86YL7, O60836, O95128, Q7L375, Q8NBQ8, Q8NBR3	Gene names	PDPN, GP36
Domain Architecture	No domain graphic available
Description	Podoplanin precursor (Glycoprotein 36) (Gp36) (PA2.26 antigen) (T1A) (T1-alpha) (Aggrus).

PPR3A_MOUSE
θ value	2.36792 (rank : 77)	NC score	0.027113 (rank : 92)
Query Neighborhood Hits	181	Target Neighborhood Hits	45	Shared Neighborhood Hits	3
SwissProt Accessions	Q99MR9, Q8BUJ4, Q8BUL0	Gene names	Ppp1r3a, Pp1g
Domain Architecture	No domain graphic available
Description	Protein phosphatase 1 regulatory subunit 3A (Protein phosphatase 1 glycogen-associated regulatory subunit) (Protein phosphatase type-1 glycogen targeting subunit) (RGL).

SKI_MOUSE
θ value	2.36792 (rank : 78)	NC score	0.020610 (rank : 111)
Query Neighborhood Hits	181	Target Neighborhood Hits	423	Shared Neighborhood Hits	14
SwissProt Accessions	Q60698, Q8VIL5	Gene names	Ski
Domain Architecture	No domain graphic available
Description	Ski oncogene (C-ski).

TENS1_HUMAN
θ value	2.36792 (rank : 79)	NC score	0.033912 (rank : 71)
Query Neighborhood Hits	181	Target Neighborhood Hits	400	Shared Neighborhood Hits	22
SwissProt Accessions	Q9HBL0	Gene names	TNS1, TNS
Domain Architecture	No domain graphic available
Description	Tensin-1.

TRI36_HUMAN
θ value	2.36792 (rank : 80)	NC score	0.011832 (rank : 151)
Query Neighborhood Hits	181	Target Neighborhood Hits	282	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NQ86	Gene names	TRIM36, RBCC728, RNF98
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Zinc-binding protein Rbcc728) (RING finger protein 98).

WTAP_MOUSE
θ value	2.36792 (rank : 81)	NC score	0.034381 (rank : 70)
Query Neighborhood Hits	181	Target Neighborhood Hits	250	Shared Neighborhood Hits	8
SwissProt Accessions	Q9ER69	Gene names	Wtap
Domain Architecture	No domain graphic available
Description	Wilms' tumor 1-associating protein (WT1-associated protein) (Putative pre-mRNA-splicing regulator female-lethal(2D) homolog).

APLP2_MOUSE
θ value	3.0926 (rank : 82)	NC score	0.039708 (rank : 56)
Query Neighborhood Hits	181	Target Neighborhood Hits	186	Shared Neighborhood Hits	14
SwissProt Accessions	Q06335	Gene names	Aplp2
Domain Architecture
Description	Amyloid-like protein 2 precursor (CDEI box-binding protein) (CDEBP).

CO3A1_HUMAN
θ value	3.0926 (rank : 83)	NC score	0.017875 (rank : 120)
Query Neighborhood Hits	181	Target Neighborhood Hits	452	Shared Neighborhood Hits	27
SwissProt Accessions	P02461, Q15112, Q16403, Q6LDB3, Q6LDJ2, Q6LDJ3, Q7KZ56	Gene names	COL3A1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

DOCK2_MOUSE
θ value	3.0926 (rank : 84)	NC score	0.012758 (rank : 144)
Query Neighborhood Hits	181	Target Neighborhood Hits	104	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C3J5, Q99M79	Gene names	Dock2
Domain Architecture
Description	Dedicator of cytokinesis protein 2 (Hch protein).

GLI1_MOUSE
θ value	3.0926 (rank : 85)	NC score	0.005442 (rank : 179)
Query Neighborhood Hits	181	Target Neighborhood Hits	785	Shared Neighborhood Hits	17
SwissProt Accessions	P47806, Q9QYK1	Gene names	Gli1, Gli
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI1 (Glioma-associated oncogene homolog).

MUC1_MOUSE
θ value	3.0926 (rank : 86)	NC score	0.090532 (rank : 7)
Query Neighborhood Hits	181	Target Neighborhood Hits	388	Shared Neighborhood Hits	32
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

NOLC1_HUMAN
θ value	3.0926 (rank : 87)	NC score	0.046953 (rank : 36)
Query Neighborhood Hits	181	Target Neighborhood Hits	452	Shared Neighborhood Hits	28
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

RFX1_HUMAN
θ value	3.0926 (rank : 88)	NC score	0.028460 (rank : 88)
Query Neighborhood Hits	181	Target Neighborhood Hits	256	Shared Neighborhood Hits	26
SwissProt Accessions	P22670	Gene names	RFX1
Domain Architecture
Description	MHC class II regulatory factor RFX1 (RFX) (Enhancer factor C) (EF-C).

SSH2_HUMAN
θ value	3.0926 (rank : 89)	NC score	0.031035 (rank : 76)
Query Neighborhood Hits	181	Target Neighborhood Hits	140	Shared Neighborhood Hits	12
SwissProt Accessions	Q76I76, Q8TDB5, Q8WYL1, Q8WYL2, Q96F40, Q96H36, Q9C0D8	Gene names	SSH2, KIAA1725, SSH2L
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 2 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-2L) (hSSH-2L).

STA13_MOUSE
θ value	3.0926 (rank : 90)	NC score	0.012483 (rank : 146)
Query Neighborhood Hits	181	Target Neighborhood Hits	89	Shared Neighborhood Hits	4
SwissProt Accessions	Q923Q2, Q8K369	Gene names	Stard13
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13).

CENPC_HUMAN
θ value	4.03905 (rank : 91)	NC score	0.028543 (rank : 87)
Query Neighborhood Hits	181	Target Neighborhood Hits	147	Shared Neighborhood Hits	8
SwissProt Accessions	Q03188, Q9P0M5	Gene names	CENPC1, CENPC, ICEN7
Domain Architecture	No domain graphic available
Description	Centromere protein C 1 (CENP-C) (Centromere autoantigen C) (Interphase centromere complex protein 7).

CEP63_HUMAN
θ value	4.03905 (rank : 92)	NC score	0.010904 (rank : 155)
Query Neighborhood Hits	181	Target Neighborhood Hits	1005	Shared Neighborhood Hits	21
SwissProt Accessions	Q96MT8, Q96CR0, Q9H8F5, Q9H8N0	Gene names	CEP63
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 63 kDa (Cep63 protein).

CHD8_HUMAN
θ value	4.03905 (rank : 93)	NC score	0.010530 (rank : 159)
Query Neighborhood Hits	181	Target Neighborhood Hits	235	Shared Neighborhood Hits	15
SwissProt Accessions	Q9HCK8, Q68DQ0, Q8N3Z9, Q8NCY4, Q8TBR9, Q96F26	Gene names	CHD8, HELSNF1, KIAA1564
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 8 (EC 3.6.1.-) (ATP- dependent helicase CHD8) (CHD-8) (Helicase with SNF2 domain 1).

CIC_MOUSE
θ value	4.03905 (rank : 94)	NC score	0.032427 (rank : 73)
Query Neighborhood Hits	181	Target Neighborhood Hits	742	Shared Neighborhood Hits	48
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

FGD1_HUMAN
θ value	4.03905 (rank : 95)	NC score	0.017735 (rank : 121)
Query Neighborhood Hits	181	Target Neighborhood Hits	367	Shared Neighborhood Hits	22
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

GAK_MOUSE
θ value	4.03905 (rank : 96)	NC score	0.008422 (rank : 169)
Query Neighborhood Hits	181	Target Neighborhood Hits	964	Shared Neighborhood Hits	21
SwissProt Accessions	Q99KY4, Q6P1I8, Q6P9S5, Q8BM74, Q8K0Q4	Gene names	Gak
Domain Architecture	No domain graphic available
Description	Cyclin G-associated kinase (EC 2.7.11.1).

GLI2_HUMAN
θ value	4.03905 (rank : 97)	NC score	0.006712 (rank : 175)
Query Neighborhood Hits	181	Target Neighborhood Hits	971	Shared Neighborhood Hits	27
SwissProt Accessions	P10070, O60252, O60253, O60254, O60255, Q15590, Q15591	Gene names	GLI2, THP
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI2 (Tax helper protein).

GLIS3_HUMAN
θ value	4.03905 (rank : 98)	NC score	0.004508 (rank : 182)
Query Neighborhood Hits	181	Target Neighborhood Hits	758	Shared Neighborhood Hits	17
SwissProt Accessions	Q8NEA6	Gene names	GLIS3, ZNF515
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLIS3 (GLI-similar 3) (Zinc finger protein 515).

INPP_HUMAN
θ value	4.03905 (rank : 99)	NC score	0.023106 (rank : 101)
Query Neighborhood Hits	181	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	P49441	Gene names	INPP1
Domain Architecture
Description	Inositol polyphosphate 1-phosphatase (EC 3.1.3.57) (IPPase) (IPP).

MAP4_MOUSE
θ value	4.03905 (rank : 100)	NC score	0.059472 (rank : 21)
Query Neighborhood Hits	181	Target Neighborhood Hits	409	Shared Neighborhood Hits	34
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

MBD5_HUMAN
θ value	4.03905 (rank : 101)	NC score	0.035113 (rank : 66)
Query Neighborhood Hits	181	Target Neighborhood Hits	176	Shared Neighborhood Hits	19
SwissProt Accessions	Q9P267, Q9NUV6	Gene names	MBD5, KIAA1461
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 5 (Methyl-CpG-binding protein MBD5).

MK07_MOUSE
θ value	4.03905 (rank : 102)	NC score	0.006222 (rank : 177)
Query Neighborhood Hits	181	Target Neighborhood Hits	1054	Shared Neighborhood Hits	27
SwissProt Accessions	Q9WVS8	Gene names	Mapk7, Erk5
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (BMK1 kinase).

MLL2_HUMAN
θ value	4.03905 (rank : 103)	NC score	0.043965 (rank : 44)
Query Neighborhood Hits	181	Target Neighborhood Hits	1788	Shared Neighborhood Hits	74
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

P73L_HUMAN
θ value	4.03905 (rank : 104)	NC score	0.020056 (rank : 113)
Query Neighborhood Hits	181	Target Neighborhood Hits	102	Shared Neighborhood Hits	14
SwissProt Accessions	Q9H3D4, O75080, O75195, O75922, O76078, Q6VEG2, Q6VEG3, Q6VEG4, Q6VFJ1, Q6VFJ2, Q6VFJ3, Q6VH20, Q7LDI3, Q7LDI4, Q7LDI5, Q96KR0, Q9H3D2, Q9H3D3, Q9H3P8, Q9NPH7, Q9P1B4, Q9P1B5, Q9P1B6, Q9P1B7, Q9UBV9, Q9UE10, Q9UP26, Q9UP27, Q9UP28, Q9UP74	Gene names	TP73L, KET, P63, P73H, P73L
Domain Architecture	No domain graphic available
Description	Tumor protein p73-like (p73L) (p63) (Tumor protein 63) (TP63) (p51) (p40) (Keratinocyte transcription factor KET) (Chronic ulcerative stomatitis protein) (CUSP).

PCDA6_HUMAN
θ value	4.03905 (rank : 105)	NC score	0.002887 (rank : 184)
Query Neighborhood Hits	181	Target Neighborhood Hits	187	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UN73, O75283, Q9NRT8	Gene names	PCDHA6
Domain Architecture
Description	Protocadherin alpha 6 precursor (PCDH-alpha6).

PO121_MOUSE
θ value	4.03905 (rank : 106)	NC score	0.047145 (rank : 33)
Query Neighborhood Hits	181	Target Neighborhood Hits	345	Shared Neighborhood Hits	31
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

WTAP_HUMAN
θ value	4.03905 (rank : 107)	NC score	0.030204 (rank : 81)
Query Neighborhood Hits	181	Target Neighborhood Hits	262	Shared Neighborhood Hits	8
SwissProt Accessions	Q15007, Q96T28, Q9BYJ7, Q9H4E2	Gene names	WTAP, KIAA0105
Domain Architecture	No domain graphic available
Description	Wilms' tumor 1-associating protein (WT1-associated protein) (Putative pre-mRNA-splicing regulator female-lethal(2D) homolog).

ZBT40_HUMAN
θ value	4.03905 (rank : 108)	NC score	0.002845 (rank : 185)
Query Neighborhood Hits	181	Target Neighborhood Hits	949	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NUA8, O75066, Q5TFU5, Q8N1R1	Gene names	ZBTB40, KIAA0478
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 40.

A4_MOUSE
θ value	5.27518 (rank : 109)	NC score	0.034663 (rank : 68)
Query Neighborhood Hits	181	Target Neighborhood Hits	275	Shared Neighborhood Hits	13
SwissProt Accessions	P12023, P97487, P97942, Q99K32	Gene names	App
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 protein precursor (APP) (ABPP) (Alzheimer disease amyloid protein homolog) (Amyloidogenic glycoprotein) (AG) [Contains: Soluble APP-alpha (S-APP-alpha); Soluble APP-beta (S-APP-beta); C99 (APP-C99); Beta-amyloid protein 42 (Beta-APP42); Beta-amyloid protein 40 (Beta-APP40); C83; P3(42); P3(40); Gamma-CTF(59) (Gamma-secretase C-terminal fragment 59) (Amyloid intracellular domain 59) (AID(59)) (APP-C59); Gamma-CTF(57) (Gamma-secretase C-terminal fragment 57) (Amyloid intracellular domain 57) (AID(57)) (APP-C57); Gamma-CTF(50) (Gamma-secretase C-terminal fragment 50) (Amyloid intracellular domain 50) (AID(50)); C31].

AB1IP_MOUSE
θ value	5.27518 (rank : 110)	NC score	0.018413 (rank : 119)
Query Neighborhood Hits	181	Target Neighborhood Hits	181	Shared Neighborhood Hits	10
SwissProt Accessions	Q8R5A3, O35329, Q8BRU0, Q99KV8	Gene names	Apbb1ip, Prel1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 48).

ABP1_HUMAN
θ value	5.27518 (rank : 111)	NC score	0.012744 (rank : 145)
Query Neighborhood Hits	181	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	P19801, Q16683, Q16684, Q56II4, Q6GU42	Gene names	ABP1, AOC1, DAO1
Domain Architecture
Description	Amiloride-sensitive amine oxidase [copper-containing] precursor (EC 1.4.3.6) (Diamine oxidase) (DAO) (Amiloride-binding protein) (ABP) (Histaminase) (Kidney amine oxidase) (KAO).

AFF2_HUMAN
θ value	5.27518 (rank : 112)	NC score	0.041290 (rank : 51)
Query Neighborhood Hits	181	Target Neighborhood Hits	218	Shared Neighborhood Hits	17
SwissProt Accessions	P51816, O43786, O60215, P78407, Q13521, Q14323, Q9UNA5	Gene names	AFF2, FMR2, OX19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation 2 protein) (Protein FMR-2) (FMR2P) (Protein Ox19) (Fragile X E mental retardation syndrome protein).

ANR35_HUMAN
θ value	5.27518 (rank : 113)	NC score	0.010109 (rank : 162)
Query Neighborhood Hits	181	Target Neighborhood Hits	784	Shared Neighborhood Hits	14
SwissProt Accessions	Q8N283, Q3MJ10, Q96LS3	Gene names	ANKRD35
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 35.

BMP2K_MOUSE
θ value	5.27518 (rank : 114)	NC score	0.009471 (rank : 166)
Query Neighborhood Hits	181	Target Neighborhood Hits	874	Shared Neighborhood Hits	18
SwissProt Accessions	Q91Z96, Q8C8L7	Gene names	Bmp2k, Bike
Domain Architecture
Description	BMP-2-inducible protein kinase (EC 2.7.11.1) (BIKe).

CD2L2_HUMAN
θ value	5.27518 (rank : 115)	NC score	0.005305 (rank : 180)
Query Neighborhood Hits	181	Target Neighborhood Hits	1439	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UQ88, O95227, O95228, O96012, Q12821, Q12853, Q12854, Q5QPR0, Q5QPR1, Q5QPR2, Q9UBC4, Q9UBI3, Q9UEI1, Q9UEI2, Q9UP53, Q9UP54, Q9UP55, Q9UP56, Q9UQ86, Q9UQ87, Q9UQ89	Gene names	CDC2L2, PITSLREB
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L2 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 2) (CDK11).

CG1_HUMAN
θ value	5.27518 (rank : 116)	NC score	0.045226 (rank : 41)
Query Neighborhood Hits	181	Target Neighborhood Hits	222	Shared Neighborhood Hits	21
SwissProt Accessions	Q13495	Gene names	CXorf6, CG1
Domain Architecture	No domain graphic available
Description	CG1 protein (F18).

COHA1_HUMAN
θ value	5.27518 (rank : 117)	NC score	0.023878 (rank : 98)
Query Neighborhood Hits	181	Target Neighborhood Hits	400	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UMD9, Q02802, Q99018, Q9NQK9, Q9UC14	Gene names	COL17A1, BP180, BPAG2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

FXL19_MOUSE
θ value	5.27518 (rank : 118)	NC score	0.020030 (rank : 114)
Query Neighborhood Hits	181	Target Neighborhood Hits	217	Shared Neighborhood Hits	10
SwissProt Accessions	Q6PB97, Q7TSH0, Q8BIB4	Gene names	Fbxl19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

NFH_MOUSE
θ value	5.27518 (rank : 119)	NC score	0.034777 (rank : 67)
Query Neighborhood Hits	181	Target Neighborhood Hits	2247	Shared Neighborhood Hits	93
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

OSTP_HUMAN
θ value	5.27518 (rank : 120)	NC score	0.038791 (rank : 58)
Query Neighborhood Hits	181	Target Neighborhood Hits	36	Shared Neighborhood Hits	7
SwissProt Accessions	P10451, Q15681, Q15682, Q15683, Q8NBK2, Q96IZ1	Gene names	SPP1, OPN
Domain Architecture
Description	Osteopontin precursor (Bone sialoprotein-1) (Secreted phosphoprotein 1) (SPP-1) (Urinary stone protein) (Nephropontin) (Uropontin).

PIWL1_HUMAN
θ value	5.27518 (rank : 121)	NC score	0.013709 (rank : 136)
Query Neighborhood Hits	181	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	Q96J94, O95404, Q8NA60, Q8TBY5, Q96JD5	Gene names	PIWIL1, HIWI
Domain Architecture	No domain graphic available
Description	Piwi-like protein 1.

PIWL1_MOUSE
θ value	5.27518 (rank : 122)	NC score	0.013779 (rank : 135)
Query Neighborhood Hits	181	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JMB7	Gene names	Piwil1, Miwi
Domain Architecture	No domain graphic available
Description	Piwi-like protein 1.

PLK4_MOUSE
θ value	5.27518 (rank : 123)	NC score	0.001687 (rank : 186)
Query Neighborhood Hits	181	Target Neighborhood Hits	879	Shared Neighborhood Hits	11
SwissProt Accessions	Q64702, Q6PEP6, Q78EG6, Q8R0I5, Q9CVR6, Q9CVU6	Gene names	Plk4, Sak, Stk18
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase Sak) (Serine/threonine- protein kinase 18).

RTN1_MOUSE
θ value	5.27518 (rank : 124)	NC score	0.017207 (rank : 123)
Query Neighborhood Hits	181	Target Neighborhood Hits	189	Shared Neighborhood Hits	13
SwissProt Accessions	Q8K0T0, Q8K4S4	Gene names	Rtn1, Nsp
Domain Architecture	No domain graphic available
Description	Reticulon-1 (Neuroendocrine-specific protein).

TACC3_HUMAN
θ value	5.27518 (rank : 125)	NC score	0.022726 (rank : 103)
Query Neighborhood Hits	181	Target Neighborhood Hits	779	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

AFF1_HUMAN
θ value	6.88961 (rank : 126)	NC score	0.066754 (rank : 16)
Query Neighborhood Hits	181	Target Neighborhood Hits	506	Shared Neighborhood Hits	34
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

ATF7_MOUSE
θ value	6.88961 (rank : 127)	NC score	0.013660 (rank : 137)
Query Neighborhood Hits	181	Target Neighborhood Hits	286	Shared Neighborhood Hits	10
SwissProt Accessions	Q8R0S1	Gene names	Atf7
Domain Architecture	No domain graphic available
Description	Cyclic AMP-dependent transcription factor ATF-7 (Activating transcription factor 7) (Transcription factor ATF-A).

BRD4_HUMAN
θ value	6.88961 (rank : 128)	NC score	0.034580 (rank : 69)
Query Neighborhood Hits	181	Target Neighborhood Hits	851	Shared Neighborhood Hits	40
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

CCD60_HUMAN
θ value	6.88961 (rank : 129)	NC score	0.017180 (rank : 124)
Query Neighborhood Hits	181	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IWA6	Gene names	CCDC60
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 60.

CIC_HUMAN
θ value	6.88961 (rank : 130)	NC score	0.032486 (rank : 72)
Query Neighborhood Hits	181	Target Neighborhood Hits	992	Shared Neighborhood Hits	53
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CN044_HUMAN
θ value	6.88961 (rank : 131)	NC score	0.020337 (rank : 112)
Query Neighborhood Hits	181	Target Neighborhood Hits	227	Shared Neighborhood Hits	8
SwissProt Accessions	Q96MY7	Gene names	C14orf44
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf44.

CO039_MOUSE
θ value	6.88961 (rank : 132)	NC score	0.030100 (rank : 82)
Query Neighborhood Hits	181	Target Neighborhood Hits	445	Shared Neighborhood Hits	33
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

COHA1_MOUSE
θ value	6.88961 (rank : 133)	NC score	0.024602 (rank : 97)
Query Neighborhood Hits	181	Target Neighborhood Hits	414	Shared Neighborhood Hits	28
SwissProt Accessions	Q07563, Q99LK8	Gene names	Col17a1, Bp180, Bpag2
Domain Architecture
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

CP135_HUMAN
θ value	6.88961 (rank : 134)	NC score	0.008081 (rank : 171)
Query Neighborhood Hits	181	Target Neighborhood Hits	1290	Shared Neighborhood Hits	23
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

EYA3_HUMAN
θ value	6.88961 (rank : 135)	NC score	0.013572 (rank : 138)
Query Neighborhood Hits	181	Target Neighborhood Hits	45	Shared Neighborhood Hits	5
SwissProt Accessions	Q99504, O95463, Q99813	Gene names	EYA3
Domain Architecture
Description	Eyes absent homolog 3 (EC 3.1.3.48).

EYA3_MOUSE
θ value	6.88961 (rank : 136)	NC score	0.013291 (rank : 140)
Query Neighborhood Hits	181	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	P97480, P97768	Gene names	Eya3
Domain Architecture
Description	Eyes absent homolog 3 (EC 3.1.3.48).

FOLC_MOUSE
θ value	6.88961 (rank : 137)	NC score	0.016482 (rank : 126)
Query Neighborhood Hits	181	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	P48760	Gene names	Fpgs
Domain Architecture
Description	Folylpolyglutamate synthase, mitochondrial precursor (EC 6.3.2.17) (Folylpoly-gamma-glutamate synthetase) (FPGS) (Tetrahydrofolate synthase) (Tetrahydrofolylpolyglutamate synthase).

GRIP1_MOUSE
θ value	6.88961 (rank : 138)	NC score	0.009710 (rank : 165)
Query Neighborhood Hits	181	Target Neighborhood Hits	241	Shared Neighborhood Hits	4
SwissProt Accessions	Q925T6, Q8BLQ3, Q8C0T3, Q925T5, Q925T7	Gene names	Grip1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

GTSE1_MOUSE
θ value	6.88961 (rank : 139)	NC score	0.029193 (rank : 86)
Query Neighborhood Hits	181	Target Neighborhood Hits	245	Shared Neighborhood Hits	16
SwissProt Accessions	Q8R080, O89015, Q9CSG9	Gene names	Gtse1, B99
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (Gtse-1) (B99 protein).

ITB4_HUMAN
θ value	6.88961 (rank : 140)	NC score	0.006923 (rank : 173)
Query Neighborhood Hits	181	Target Neighborhood Hits	458	Shared Neighborhood Hits	12
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

KI13B_HUMAN
θ value	6.88961 (rank : 141)	NC score	0.012382 (rank : 147)
Query Neighborhood Hits	181	Target Neighborhood Hits	492	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NQT8, O75134, Q9BYJ6	Gene names	KIF13B, GAKIN, KIAA0639
Domain Architecture
Description	Kinesin-like protein KIF13B (Kinesin-like protein GAKIN).

KIF1C_HUMAN
θ value	6.88961 (rank : 142)	NC score	0.011112 (rank : 153)
Query Neighborhood Hits	181	Target Neighborhood Hits	128	Shared Neighborhood Hits	6
SwissProt Accessions	O43896, O75186	Gene names	KIF1C, KIAA0706
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF1C.

KIF1C_MOUSE
θ value	6.88961 (rank : 143)	NC score	0.010955 (rank : 154)
Query Neighborhood Hits	181	Target Neighborhood Hits	171	Shared Neighborhood Hits	8
SwissProt Accessions	O35071, Q5SX62	Gene names	Kif1c
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF1C.

MTSS1_MOUSE
θ value	6.88961 (rank : 144)	NC score	0.027395 (rank : 91)
Query Neighborhood Hits	181	Target Neighborhood Hits	592	Shared Neighborhood Hits	36
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

MUC5B_HUMAN
θ value	6.88961 (rank : 145)	NC score	0.041718 (rank : 49)
Query Neighborhood Hits	181	Target Neighborhood Hits	1020	Shared Neighborhood Hits	43
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

MYPC3_MOUSE
θ value	6.88961 (rank : 146)	NC score	0.007822 (rank : 172)
Query Neighborhood Hits	181	Target Neighborhood Hits	310	Shared Neighborhood Hits	6
SwissProt Accessions	O70468, O88997	Gene names	Mybpc3
Domain Architecture
Description	Myosin-binding protein C, cardiac-type (Cardiac MyBP-C) (C-protein, cardiac muscle isoform).

NCOA3_HUMAN
θ value	6.88961 (rank : 147)	NC score	0.011913 (rank : 149)
Query Neighborhood Hits	181	Target Neighborhood Hits	171	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y6Q9, Q5JYD9, Q5JYE0, Q9BR49, Q9UPC9, Q9UPG4, Q9UPG7	Gene names	NCOA3, AIB1, RAC3, TRAM1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP-interacting protein) (pCIP).

NTHL1_HUMAN
θ value	6.88961 (rank : 148)	NC score	0.031790 (rank : 75)
Query Neighborhood Hits	181	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	P78549, Q99566, Q99794, Q9BPX2	Gene names	NTHL1, NTH1, OCTS3
Domain Architecture
Description	Endonuclease III-like protein 1 (EC 4.2.99.18).

OBFC1_MOUSE
θ value	6.88961 (rank : 149)	NC score	0.018467 (rank : 118)
Query Neighborhood Hits	181	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K2X3, Q8C6I6	Gene names	Obfc1
Domain Architecture	No domain graphic available
Description	Oligonucleotide/oligosaccharide-binding fold-containing protein 1.

PCX1_HUMAN
θ value	6.88961 (rank : 150)	NC score	0.025167 (rank : 96)
Query Neighborhood Hits	181	Target Neighborhood Hits	102	Shared Neighborhood Hits	9
SwissProt Accessions	Q96RV3, O94897, Q96AI7, Q9Y2J9	Gene names	PCNX, KIAA0805, KIAA0995, PCNXL1
Domain Architecture
Description	Pecanex-like protein 1 (Pecanex homolog).

PER3_MOUSE
θ value	6.88961 (rank : 151)	NC score	0.009930 (rank : 163)
Query Neighborhood Hits	181	Target Neighborhood Hits	85	Shared Neighborhood Hits	3
SwissProt Accessions	O70361	Gene names	Per3
Domain Architecture
Description	Period circadian protein 3 (mPER3).

PHLPP_HUMAN
θ value	6.88961 (rank : 152)	NC score	0.010621 (rank : 158)
Query Neighborhood Hits	181	Target Neighborhood Hits	604	Shared Neighborhood Hits	18
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

PHLPP_MOUSE
θ value	6.88961 (rank : 153)	NC score	0.008948 (rank : 167)
Query Neighborhood Hits	181	Target Neighborhood Hits	394	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CHE4, Q6PCN0, Q8QZU8, Q8R5E5, Q99KL6	Gene names	Phlpp, Kiaa0606, Plekhe1, Scop
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein).

PKHA3_HUMAN
θ value	6.88961 (rank : 154)	NC score	0.014156 (rank : 133)
Query Neighborhood Hits	181	Target Neighborhood Hits	66	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HB20, Q86TQ1, Q9NXT3	Gene names	PLEKHA3, FAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 3 (Phosphoinositol 4-phosphate adaptor protein 1) (FAPP-1).

PPRB_HUMAN
θ value	6.88961 (rank : 155)	NC score	0.037490 (rank : 62)
Query Neighborhood Hits	181	Target Neighborhood Hits	311	Shared Neighborhood Hits	28
SwissProt Accessions	Q15648, O43810, O75447, Q9HD39	Gene names	PPARBP, ARC205, DRIP205, TRAP220, TRIP2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2) (p53 regulatory protein RB18A) (Vitamin D receptor-interacting protein complex component DRIP205) (Activator- recruited cofactor 205 kDa component) (ARC205).

SOS1_MOUSE
θ value	6.88961 (rank : 156)	NC score	0.012920 (rank : 143)
Query Neighborhood Hits	181	Target Neighborhood Hits	281	Shared Neighborhood Hits	12
SwissProt Accessions	Q62245, Q62244	Gene names	Sos1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1) (mSOS-1).

TAU_HUMAN
θ value	6.88961 (rank : 157)	NC score	0.037254 (rank : 63)
Query Neighborhood Hits	181	Target Neighborhood Hits	448	Shared Neighborhood Hits	35
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

TF3C2_MOUSE
θ value	6.88961 (rank : 158)	NC score	0.016059 (rank : 128)
Query Neighborhood Hits	181	Target Neighborhood Hits	165	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BL74, Q3U7Z9, Q80XQ7, Q8BJJ4, Q8BLP3, Q8K1J1, Q9CSS0, Q9CVE6, Q9DBK6	Gene names	Gtf3c2, Kiaa0011
Domain Architecture
Description	General transcription factor 3C polypeptide 2 (Transcription factor IIIC-subunit beta) (TF3C-beta) (TFIIIC 110 kDa subunit) (TFIIIC110).

THB1_MOUSE
θ value	6.88961 (rank : 159)	NC score	0.003631 (rank : 183)
Query Neighborhood Hits	181	Target Neighborhood Hits	105	Shared Neighborhood Hits	2
SwissProt Accessions	P37242	Gene names	Thrb, C-erba-beta, Nr1a2
Domain Architecture
Description	Thyroid hormone receptor beta-1.

AGGF1_HUMAN
θ value	8.99809 (rank : 160)	NC score	0.013116 (rank : 142)
Query Neighborhood Hits	181	Target Neighborhood Hits	271	Shared Neighborhood Hits	10
SwissProt Accessions	Q8N302, O00581, Q53YS3, Q9BU84, Q9NW66	Gene names	AGGF1, VG5Q
Domain Architecture
Description	Angiogenic factor with G patch and FHA domains 1 (Angiogenic factor VG5Q) (Vasculogenesis gene on 5q protein) (hVG5Q).

ARI4A_HUMAN
θ value	8.99809 (rank : 161)	NC score	0.022331 (rank : 105)
Query Neighborhood Hits	181	Target Neighborhood Hits	434	Shared Neighborhood Hits	22
SwissProt Accessions	P29374, Q15991, Q15992, Q15993	Gene names	ARID4A, RBBP1, RBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 4A (ARID domain- containing protein 4A) (Retinoblastoma-binding protein 1) (RBBP-1).

BSND_MOUSE
θ value	8.99809 (rank : 162)	NC score	0.016260 (rank : 127)
Query Neighborhood Hits	181	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VIM4, Q8C740, Q8CHY0	Gene names	Bsnd
Domain Architecture	No domain graphic available
Description	Barttin.

CB013_MOUSE
θ value	8.99809 (rank : 163)	NC score	0.014700 (rank : 131)
Query Neighborhood Hits	181	Target Neighborhood Hits	43	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D842, Q8BZL5, Q99LX6	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C2orf13 homolog.

CENPC_MOUSE
θ value	8.99809 (rank : 164)	NC score	0.025172 (rank : 95)
Query Neighborhood Hits	181	Target Neighborhood Hits	154	Shared Neighborhood Hits	12
SwissProt Accessions	P49452	Gene names	Cenpc1, Cenpc
Domain Architecture	No domain graphic available
Description	Centromere protein C 1 (CENP-C) (Centromere autoantigen C).

CJ047_MOUSE
θ value	8.99809 (rank : 165)	NC score	0.021827 (rank : 106)
Query Neighborhood Hits	181	Target Neighborhood Hits	76	Shared Neighborhood Hits	7
SwissProt Accessions	Q8C5R2, Q8R017, Q8R2Z9	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf47 homolog.

CN044_MOUSE
θ value	8.99809 (rank : 166)	NC score	0.022531 (rank : 104)
Query Neighborhood Hits	181	Target Neighborhood Hits	57	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CB59, Q8BQX8, Q8BSL9, Q8CBZ3	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf44 homolog.

ELL_HUMAN
θ value	8.99809 (rank : 167)	NC score	0.014357 (rank : 132)
Query Neighborhood Hits	181	Target Neighborhood Hits	183	Shared Neighborhood Hits	13
SwissProt Accessions	P55199	Gene names	ELL, C19orf17
Domain Architecture
Description	RNA polymerase II elongation factor ELL (Eleven-nineteen lysine-rich leukemia protein).

FOXP4_MOUSE
θ value	8.99809 (rank : 168)	NC score	0.006348 (rank : 176)
Query Neighborhood Hits	181	Target Neighborhood Hits	211	Shared Neighborhood Hits	11
SwissProt Accessions	Q9DBY0, Q80V92, Q8CG10, Q8CIS1	Gene names	Foxp4
Domain Architecture	No domain graphic available
Description	Forkhead box protein P4 (Fork head-related protein like A) (mFKHLA).

LIMA1_HUMAN
θ value	8.99809 (rank : 169)	NC score	0.010638 (rank : 157)
Query Neighborhood Hits	181	Target Neighborhood Hits	309	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UHB6, Q2TAN7, Q9BVF2, Q9H8J1, Q9HBN5, Q9NX96, Q9NXC3, Q9NXU6, Q9P0H8, Q9UHB5	Gene names	LIMA1, EPLIN, SREBP3
Domain Architecture
Description	LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm).

MAP1A_HUMAN
θ value	8.99809 (rank : 170)	NC score	0.030383 (rank : 80)
Query Neighborhood Hits	181	Target Neighborhood Hits	1626	Shared Neighborhood Hits	62
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

MLL3_MOUSE
θ value	8.99809 (rank : 171)	NC score	0.032075 (rank : 74)
Query Neighborhood Hits	181	Target Neighborhood Hits	1399	Shared Neighborhood Hits	67
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

MYLK_MOUSE
θ value	8.99809 (rank : 172)	NC score	0.004654 (rank : 181)
Query Neighborhood Hits	181	Target Neighborhood Hits	1489	Shared Neighborhood Hits	40
SwissProt Accessions	Q6PDN3, Q3TSJ7, Q80UX0, Q80YN7, Q80YN8, Q8K026, Q924D2, Q9ERD3	Gene names	Mylk
Domain Architecture	No domain graphic available
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

NFIB_HUMAN
θ value	8.99809 (rank : 173)	NC score	0.008189 (rank : 170)
Query Neighborhood Hits	181	Target Neighborhood Hits	66	Shared Neighborhood Hits	5
SwissProt Accessions	O00712, O00166, Q12858, Q96J45	Gene names	NFIB
Domain Architecture
Description	Nuclear factor 1 B-type (Nuclear factor 1/B) (NF1-B) (NFI-B) (NF-I/B) (CCAAT-box-binding transcription factor) (CTF) (TGGCA-binding protein).

PPE2_MOUSE
θ value	8.99809 (rank : 174)	NC score	0.006908 (rank : 174)
Query Neighborhood Hits	181	Target Neighborhood Hits	112	Shared Neighborhood Hits	2
SwissProt Accessions	O35385	Gene names	Ppef2
Domain Architecture
Description	Serine/threonine-protein phosphatase with EF-hands 2 (EC 3.1.3.16) (PPEF-2).

PPGB_HUMAN
θ value	8.99809 (rank : 175)	NC score	0.012033 (rank : 148)
Query Neighborhood Hits	181	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	P10619, Q5JZH1, Q96KJ2, Q9BR08, Q9BW68	Gene names	PPGB
Domain Architecture
Description	Lysosomal protective protein precursor (EC 3.4.16.5) (Cathepsin A) (Carboxypeptidase C) (Protective protein for beta-galactosidase) [Contains: Lysosomal protective protein 32 kDa chain; Lysosomal protective protein 20 kDa chain].

PRDM2_HUMAN
θ value	8.99809 (rank : 176)	NC score	0.008436 (rank : 168)
Query Neighborhood Hits	181	Target Neighborhood Hits	1135	Shared Neighborhood Hits	34
SwissProt Accessions	Q13029, Q13149, Q14550, Q5VUL9	Gene names	PRDM2, RIZ
Domain Architecture
Description	PR domain zinc finger protein 2 (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc-finger protein) (Zinc finger protein RIZ) (MTE-binding protein) (MTB-ZF) (GATA-3-binding protein G3B).

SAMD4_HUMAN
θ value	8.99809 (rank : 177)	NC score	0.013862 (rank : 134)
Query Neighborhood Hits	181	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UPU9	Gene names	SAMD4, KIAA1053
Domain Architecture
Description	Sterile alpha motif domain-containing protein 4.

SMC3_HUMAN
θ value	8.99809 (rank : 178)	NC score	0.010387 (rank : 161)
Query Neighborhood Hits	181	Target Neighborhood Hits	1186	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

SMC3_MOUSE
θ value	8.99809 (rank : 179)	NC score	0.010432 (rank : 160)
Query Neighborhood Hits	181	Target Neighborhood Hits	1187	Shared Neighborhood Hits	23
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

TCAL5_HUMAN
θ value	8.99809 (rank : 180)	NC score	0.018504 (rank : 117)
Query Neighborhood Hits	181	Target Neighborhood Hits	806	Shared Neighborhood Hits	37
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

TTLL4_HUMAN
θ value	8.99809 (rank : 181)	NC score	0.009917 (rank : 164)
Query Neighborhood Hits	181	Target Neighborhood Hits	79	Shared Neighborhood Hits	9
SwissProt Accessions	Q14679, Q8WW29	Gene names	TTLL4, KIAA0173
Domain Architecture
Description	Tubulin--tyrosine ligase-like protein 4.

MAML3_HUMAN
θ value	θ > 10 (rank : 182)	NC score	0.060989 (rank : 20)
Query Neighborhood Hits	181	Target Neighborhood Hits	323	Shared Neighborhood Hits	28
SwissProt Accessions	Q96JK9	Gene names	MAML3, KIAA1816
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 3 (Mam-3).

PCLO_HUMAN
θ value	θ > 10 (rank : 183)	NC score	0.053964 (rank : 25)
Query Neighborhood Hits	181	Target Neighborhood Hits	2046	Shared Neighborhood Hits	83
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PRG4_HUMAN
θ value	θ > 10 (rank : 184)	NC score	0.064257 (rank : 18)
Query Neighborhood Hits	181	Target Neighborhood Hits	764	Shared Neighborhood Hits	43
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

SELPL_MOUSE
θ value	θ > 10 (rank : 185)	NC score	0.054104 (rank : 24)
Query Neighborhood Hits	181	Target Neighborhood Hits	588	Shared Neighborhood Hits	45
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

VCX3_HUMAN
θ value	θ > 10 (rank : 186)	NC score	0.052211 (rank : 28)
Query Neighborhood Hits	181	Target Neighborhood Hits	105	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NNX9, Q9P0H4	Gene names	VCX3A, VCX3, VCX8R, VCXA
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 3 (VCX-A protein) (Variably charged protein X-A) (Variable charge protein on X with eight repeats) (VCX- 8r).

YLPM1_HUMAN
θ value	θ > 10 (rank : 187)	NC score	0.056483 (rank : 22)
Query Neighborhood Hits	181	Target Neighborhood Hits	670	Shared Neighborhood Hits	32
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

Hits sorted by NC score

ALMS1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	181	Target Neighborhood Hits	181	Shared Neighborhood Hits	181
SwissProt Accessions	Q8K4E0, Q6A084, Q8C9N9	Gene names	Alms1, Kiaa0328
Domain Architecture	No domain graphic available
Description	Alstrom syndrome protein 1 homolog.

ALMS1_HUMAN
NC score	0.895643 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	181	Target Neighborhood Hits	356	Shared Neighborhood Hits	37
SwissProt Accessions	Q8TCU4, Q53S05, Q580Q8, Q86VP9, Q9Y4G4	Gene names	ALMS1, KIAA0328
Domain Architecture	No domain graphic available
Description	Alstrom syndrome protein 1.

SRRM2_HUMAN
NC score	0.128256 (rank : 3)	θ value	5.44631e-05 (rank : 3)
Query Neighborhood Hits	181	Target Neighborhood Hits	1296	Shared Neighborhood Hits	58
SwissProt Accessions	Q9UQ35, O15038, O94803, Q6NSL3, Q6PIM3, Q6PK40, Q8IW17, Q96GY7, Q9P0G1, Q9UHA8, Q9UQ36, Q9UQ37, Q9UQ38, Q9UQ40	Gene names	SRRM2, KIAA0324, SRL300, SRM300
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2 (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (300 kDa nuclear matrix antigen).

NACAM_MOUSE
NC score	0.123368 (rank : 4)	θ value	9.29e-05 (rank : 4)
Query Neighborhood Hits	181	Target Neighborhood Hits	1866	Shared Neighborhood Hits	86
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

SRRM2_MOUSE
NC score	0.098836 (rank : 5)	θ value	0.62314 (rank : 26)
Query Neighborhood Hits	181	Target Neighborhood Hits	1470	Shared Neighborhood Hits	75
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

EP300_HUMAN
NC score	0.094940 (rank : 6)	θ value	0.163984 (rank : 12)
Query Neighborhood Hits	181	Target Neighborhood Hits	821	Shared Neighborhood Hits	45
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

MUC1_MOUSE
NC score	0.090532 (rank : 7)	θ value	3.0926 (rank : 86)
Query Neighborhood Hits	181	Target Neighborhood Hits	388	Shared Neighborhood Hits	32
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

CBP_HUMAN
NC score	0.084270 (rank : 8)	θ value	0.21417 (rank : 13)
Query Neighborhood Hits	181	Target Neighborhood Hits	941	Shared Neighborhood Hits	57
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CBP_MOUSE
NC score	0.079699 (rank : 9)	θ value	0.0431538 (rank : 8)
Query Neighborhood Hits	181	Target Neighborhood Hits	1051	Shared Neighborhood Hits	61
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

TFAM_MOUSE
NC score	0.078768 (rank : 10)	θ value	0.813845 (rank : 31)
Query Neighborhood Hits	181	Target Neighborhood Hits	93	Shared Neighborhood Hits	10
SwissProt Accessions	P40630, P97894, P97906, Q543I8, Q9DBM9	Gene names	Tfam, Hmgts
Domain Architecture
Description	Transcription factor A, mitochondrial precursor (mtTFA) (Testis- specific high mobility group protein) (TS-HMG).

NFRKB_HUMAN
NC score	0.076643 (rank : 11)	θ value	0.0148317 (rank : 7)
Query Neighborhood Hits	181	Target Neighborhood Hits	211	Shared Neighborhood Hits	19
SwissProt Accessions	Q6P4R8, Q12869, Q15312, Q9H048	Gene names	NFRKB
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

AFF4_MOUSE
NC score	0.073329 (rank : 12)	θ value	0.00509761 (rank : 5)
Query Neighborhood Hits	181	Target Neighborhood Hits	581	Shared Neighborhood Hits	32
SwissProt Accessions	Q9ESC8, Q8C6K4, Q8C6W3, Q8CCH3	Gene names	Aff4, Alf4
Domain Architecture	No domain graphic available
Description	AF4/FMR2 family member 4.

AKA12_HUMAN
NC score	0.069852 (rank : 13)	θ value	0.0961366 (rank : 11)
Query Neighborhood Hits	181	Target Neighborhood Hits	825	Shared Neighborhood Hits	44
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

MAP4_HUMAN
NC score	0.068674 (rank : 14)	θ value	0.279714 (rank : 14)
Query Neighborhood Hits	181	Target Neighborhood Hits	428	Shared Neighborhood Hits	38
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

VPS72_HUMAN
NC score	0.067696 (rank : 15)	θ value	0.279714 (rank : 17)
Query Neighborhood Hits	181	Target Neighborhood Hits	274	Shared Neighborhood Hits	17
SwissProt Accessions	Q15906, Q53GJ2, Q5U0R4	Gene names	VPS72, TCFL1, YL1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

AFF1_HUMAN
NC score	0.066754 (rank : 16)	θ value	6.88961 (rank : 126)
Query Neighborhood Hits	181	Target Neighborhood Hits	506	Shared Neighborhood Hits	34
SwissProt Accessions	P51825	Gene names	AFF1, AF4, FEL, MLLT2
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4) (Protein FEL).

VPS72_MOUSE
NC score	0.065519 (rank : 17)	θ value	0.365318 (rank : 18)
Query Neighborhood Hits	181	Target Neighborhood Hits	286	Shared Neighborhood Hits	15
SwissProt Accessions	Q62481, Q3U2N4, Q810A9, Q99K81	Gene names	Vps72, Tcfl1, Yl1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

PRG4_HUMAN
NC score	0.064257 (rank : 18)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	181	Target Neighborhood Hits	764	Shared Neighborhood Hits	43
SwissProt Accessions	Q92954, Q6DNC4, Q6DNC5, Q6ZMZ5, Q9BX49	Gene names	PRG4, MSF, SZP
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

ARI1A_HUMAN
NC score	0.063302 (rank : 19)	θ value	0.47712 (rank : 19)
Query Neighborhood Hits	181	Target Neighborhood Hits	787	Shared Neighborhood Hits	45
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

MAML3_HUMAN
NC score	0.060989 (rank : 20)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	181	Target Neighborhood Hits	323	Shared Neighborhood Hits	28
SwissProt Accessions	Q96JK9	Gene names	MAML3, KIAA1816
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 3 (Mam-3).

MAP4_MOUSE
NC score	0.059472 (rank : 21)	θ value	4.03905 (rank : 100)
Query Neighborhood Hits	181	Target Neighborhood Hits	409	Shared Neighborhood Hits	34
SwissProt Accessions	P27546	Gene names	Map4, Mtap4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

YLPM1_HUMAN
NC score	0.056483 (rank : 22)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	181	Target Neighborhood Hits	670	Shared Neighborhood Hits	32
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

CJ084_HUMAN
NC score	0.054316 (rank : 23)	θ value	0.62314 (rank : 24)
Query Neighborhood Hits	181	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H8W3, Q9H5V5	Gene names	C10orf84
Domain Architecture	No domain graphic available
Description	Protein C10orf84.

SELPL_MOUSE
NC score	0.054104 (rank : 24)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	181	Target Neighborhood Hits	588	Shared Neighborhood Hits	45
SwissProt Accessions	Q62170	Gene names	Selplg, Selp1, Selpl
Domain Architecture	No domain graphic available
Description	P-selectin glycoprotein ligand 1 precursor (PSGL-1) (Selectin P ligand).

PCLO_HUMAN
NC score	0.053964 (rank : 25)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	181	Target Neighborhood Hits	2046	Shared Neighborhood Hits	83
SwissProt Accessions	Q9Y6V0, O43373, O60305, Q9BVC8, Q9UIV2, Q9Y6U9	Gene names	PCLO, ACZ, KIAA0559
Domain Architecture
Description	Protein piccolo (Aczonin).

PDXL2_MOUSE
NC score	0.053705 (rank : 26)	θ value	1.38821 (rank : 51)
Query Neighborhood Hits	181	Target Neighborhood Hits	213	Shared Neighborhood Hits	24
SwissProt Accessions	Q8CAE9, Q8CFW3	Gene names	Podxl2
Domain Architecture	No domain graphic available
Description	Podocalyxin-like protein 2 precursor (Endoglycan).

KI67_HUMAN
NC score	0.052716 (rank : 27)	θ value	2.36792 (rank : 71)
Query Neighborhood Hits	181	Target Neighborhood Hits	581	Shared Neighborhood Hits	33
SwissProt Accessions	P46013	Gene names	MKI67
Domain Architecture
Description	Antigen KI-67.

VCX3_HUMAN
NC score	0.052211 (rank : 28)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	181	Target Neighborhood Hits	105	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NNX9, Q9P0H4	Gene names	VCX3A, VCX3, VCX8R, VCXA
Domain Architecture	No domain graphic available
Description	Variable charge X-linked protein 3 (VCX-A protein) (Variably charged protein X-A) (Variable charge protein on X with eight repeats) (VCX- 8r).

PDPN_HUMAN
NC score	0.050340 (rank : 29)	θ value	2.36792 (rank : 76)
Query Neighborhood Hits	181	Target Neighborhood Hits	12	Shared Neighborhood Hits	5
SwissProt Accessions	Q86YL7, O60836, O95128, Q7L375, Q8NBQ8, Q8NBR3	Gene names	PDPN, GP36
Domain Architecture	No domain graphic available
Description	Podoplanin precursor (Glycoprotein 36) (Gp36) (PA2.26 antigen) (T1A) (T1-alpha) (Aggrus).

TMUB1_HUMAN
NC score	0.050237 (rank : 30)	θ value	0.47712 (rank : 23)
Query Neighborhood Hits	181	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BVT8	Gene names	TMUB1, C7orf21
Domain Architecture
Description	Transmembrane and ubiquitin-like domain-containing protein 1 (Ubiquitin-like protein SB144).

PDZD2_HUMAN
NC score	0.048744 (rank : 31)	θ value	0.279714 (rank : 15)
Query Neighborhood Hits	181	Target Neighborhood Hits	772	Shared Neighborhood Hits	48
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

T22D2_HUMAN
NC score	0.047723 (rank : 32)	θ value	1.81305 (rank : 63)
Query Neighborhood Hits	181	Target Neighborhood Hits	250	Shared Neighborhood Hits	23
SwissProt Accessions	O75157, Q6PI50, Q9H2Z6, Q9H2Z7, Q9H2Z8	Gene names	TSC22D2, KIAA0669, TILZ4
Domain Architecture	No domain graphic available
Description	TSC22 domain family protein 2 (TSC22-related-inducible leucine zipper protein 4).

PO121_MOUSE
NC score	0.047145 (rank : 33)	θ value	4.03905 (rank : 106)
Query Neighborhood Hits	181	Target Neighborhood Hits	345	Shared Neighborhood Hits	31
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

APLP2_HUMAN
NC score	0.046997 (rank : 34)	θ value	1.38821 (rank : 43)
Query Neighborhood Hits	181	Target Neighborhood Hits	193	Shared Neighborhood Hits	11
SwissProt Accessions	Q06481	Gene names	APLP2, APPL2
Domain Architecture
Description	Amyloid-like protein 2 precursor (Amyloid protein homolog) (APPH) (CDEI box-binding protein) (CDEBP).

FA21C_HUMAN
NC score	0.046981 (rank : 35)	θ value	1.06291 (rank : 33)
Query Neighborhood Hits	181	Target Neighborhood Hits	194	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y4E1, Q5SQU4, Q5SQU5, Q7L521, Q9UG79	Gene names	FAM21C, KIAA0592
Domain Architecture	No domain graphic available
Description	Protein FAM21C.

NOLC1_HUMAN
NC score	0.046953 (rank : 36)	θ value	3.0926 (rank : 87)
Query Neighborhood Hits	181	Target Neighborhood Hits	452	Shared Neighborhood Hits	28
SwissProt Accessions	Q14978, Q15030	Gene names	NOLC1, KIAA0035
Domain Architecture
Description	Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body phosphoprotein 1).

PCLO_MOUSE
NC score	0.046922 (rank : 37)	θ value	1.38821 (rank : 50)
Query Neighborhood Hits	181	Target Neighborhood Hits	2275	Shared Neighborhood Hits	83
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

DCP1A_MOUSE
NC score	0.046809 (rank : 38)	θ value	2.36792 (rank : 68)
Query Neighborhood Hits	181	Target Neighborhood Hits	103	Shared Neighborhood Hits	13
SwissProt Accessions	Q91YD3, Q6NZE3	Gene names	Dcp1a, Mitc1, Smif
Domain Architecture	No domain graphic available
Description	mRNA decapping enzyme 1A (EC 3.-.-.-) (Transcription factor SMIF) (MAD homolog 4-interacting transcription coactivator 1) (Smad4-interacting transcriptional co-activator).

NTHL1_MOUSE
NC score	0.045760 (rank : 39)	θ value	1.38821 (rank : 49)
Query Neighborhood Hits	181	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	O35980	Gene names	Nthl1, Nth1
Domain Architecture
Description	Endonuclease III-like protein 1 (EC 4.2.99.18).

MAML1_HUMAN
NC score	0.045694 (rank : 40)	θ value	0.47712 (rank : 22)
Query Neighborhood Hits	181	Target Neighborhood Hits	228	Shared Neighborhood Hits	26
SwissProt Accessions	Q92585, Q9NZ12	Gene names	MAML1, KIAA0200
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 1 (Mam-1).

CG1_HUMAN
NC score	0.045226 (rank : 41)	θ value	5.27518 (rank : 116)
Query Neighborhood Hits	181	Target Neighborhood Hits	222	Shared Neighborhood Hits	21
SwissProt Accessions	Q13495	Gene names	CXorf6, CG1
Domain Architecture	No domain graphic available
Description	CG1 protein (F18).

PRG4_MOUSE
NC score	0.045118 (rank : 42)	θ value	1.81305 (rank : 62)
Query Neighborhood Hits	181	Target Neighborhood Hits	624	Shared Neighborhood Hits	40
SwissProt Accessions	Q9JM99, Q3UEL1, Q3V198	Gene names	Prg4, Msf, Szp
Domain Architecture	No domain graphic available
Description	Proteoglycan-4 precursor (Lubricin) (Megakaryocyte-stimulating factor) (Superficial zone proteoglycan) [Contains: Proteoglycan-4 C-terminal part].

K0146_HUMAN
NC score	0.044151 (rank : 43)	θ value	0.47712 (rank : 20)
Query Neighborhood Hits	181	Target Neighborhood Hits	48	Shared Neighborhood Hits	3
SwissProt Accessions	Q14159, Q96BI5	Gene names	KIAA0146
Domain Architecture	No domain graphic available
Description	Protein KIAA0146.

MLL2_HUMAN
NC score	0.043965 (rank : 44)	θ value	4.03905 (rank : 103)
Query Neighborhood Hits	181	Target Neighborhood Hits	1788	Shared Neighborhood Hits	74
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

ARID2_HUMAN
NC score	0.043830 (rank : 45)	θ value	2.36792 (rank : 65)
Query Neighborhood Hits	181	Target Neighborhood Hits	302	Shared Neighborhood Hits	29
SwissProt Accessions	Q68CP9, Q5EB51, Q645I3, Q6ZRY5, Q7Z3I5, Q86T28, Q96SJ6, Q9HCL5	Gene names	ARID2, KIAA1557
Domain Architecture	No domain graphic available
Description	AT-rich interactive domain-containing protein 2 (ARID domain- containing protein 2) (BRG1-associated factor 200) (BAF200).

XKR5_HUMAN
NC score	0.043809 (rank : 46)	θ value	0.62314 (rank : 28)
Query Neighborhood Hits	181	Target Neighborhood Hits	54	Shared Neighborhood Hits	12
SwissProt Accessions	Q6UX68, Q5GH74	Gene names	XKR5, XRG5
Domain Architecture	No domain graphic available
Description	XK-related protein 5.

ATX7_HUMAN
NC score	0.042162 (rank : 47)	θ value	1.06291 (rank : 32)
Query Neighborhood Hits	181	Target Neighborhood Hits	351	Shared Neighborhood Hits	24
SwissProt Accessions	O15265, O75328, O75329, Q9Y6P8	Gene names	ATXN7, SCA7
Domain Architecture	No domain graphic available
Description	Ataxin-7 (Spinocerebellar ataxia type 7 protein).

SSH2_MOUSE
NC score	0.041726 (rank : 48)	θ value	0.0431538 (rank : 9)
Query Neighborhood Hits	181	Target Neighborhood Hits	119	Shared Neighborhood Hits	9
SwissProt Accessions	Q5SW75, Q3TDK8, Q3TYP8, Q3U2K3, Q5F268, Q5SW74, Q69ZC3, Q76I78	Gene names	Ssh2, Kiaa1725, Ssh2l
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 2 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-2L) (mSSH-2L).

MUC5B_HUMAN
NC score	0.041718 (rank : 49)	θ value	6.88961 (rank : 145)
Query Neighborhood Hits	181	Target Neighborhood Hits	1020	Shared Neighborhood Hits	43
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

ZAN_MOUSE
NC score	0.041520 (rank : 50)	θ value	1.06291 (rank : 41)
Query Neighborhood Hits	181	Target Neighborhood Hits	808	Shared Neighborhood Hits	20
SwissProt Accessions	O88799, O08647	Gene names	Zan
Domain Architecture
Description	Zonadhesin precursor.

AFF2_HUMAN
NC score	0.041290 (rank : 51)	θ value	5.27518 (rank : 112)
Query Neighborhood Hits	181	Target Neighborhood Hits	218	Shared Neighborhood Hits	17
SwissProt Accessions	P51816, O43786, O60215, P78407, Q13521, Q14323, Q9UNA5	Gene names	AFF2, FMR2, OX19
Domain Architecture
Description	AF4/FMR2 family member 2 (Fragile X mental retardation 2 protein) (Protein FMR-2) (FMR2P) (Protein Ox19) (Fragile X E mental retardation syndrome protein).

A4_HUMAN
NC score	0.041069 (rank : 52)	θ value	1.38821 (rank : 42)
Query Neighborhood Hits	181	Target Neighborhood Hits	274	Shared Neighborhood Hits	14
SwissProt Accessions	P05067, P09000, P78438, Q13764, Q13778, Q13793, Q16011, Q16014, Q16019, Q16020, Q9BT38, Q9UCA9, Q9UCB6, Q9UCC8, Q9UCD1, Q9UQ58	Gene names	APP, A4, AD1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 protein precursor (APP) (ABPP) (Alzheimer disease amyloid protein) (Cerebral vascular amyloid peptide) (CVAP) (Protease nexin-II) (PN-II) (APPI) (PreA4) [Contains: Soluble APP-alpha (S-APP- alpha); Soluble APP-beta (S-APP-beta); C99; Beta-amyloid protein 42 (Beta-APP42); Beta-amyloid protein 40 (Beta-APP40); C83; P3(42); P3(40); Gamma-CTF(59) (Gamma-secretase C-terminal fragment 59) (Amyloid intracellular domain 59) (AID(59)); Gamma-CTF(57) (Gamma- secretase C-terminal fragment 57) (Amyloid intracellular domain 57) (AID(57)); Gamma-CTF(50) (Gamma-secretase C-terminal fragment 50) (Amyloid intracellular domain 50) (AID(50)); C31].

MAGE1_HUMAN
NC score	0.040686 (rank : 53)	θ value	2.36792 (rank : 74)
Query Neighborhood Hits	181	Target Neighborhood Hits	1389	Shared Neighborhood Hits	73
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

PHAR2_HUMAN
NC score	0.040537 (rank : 54)	θ value	1.38821 (rank : 52)
Query Neighborhood Hits	181	Target Neighborhood Hits	208	Shared Neighborhood Hits	16
SwissProt Accessions	O75167, Q68DM2	Gene names	PHACTR2, C6orf56, KIAA0680
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 2.

MYCB2_HUMAN
NC score	0.040286 (rank : 55)	θ value	1.38821 (rank : 48)
Query Neighborhood Hits	181	Target Neighborhood Hits	390	Shared Neighborhood Hits	19
SwissProt Accessions	O75592, Q5JSX8, Q5VZN6, Q6PIB6, Q9UQ11, Q9Y6E4	Gene names	MYCBP2, KIAA0916, PAM
Domain Architecture	No domain graphic available
Description	Probable ubiquitin ligase protein MYCBP2 (EC 6.3.2.-) (Myc-binding protein 2) (Protein associated with Myc) (Pam/highwire/rpm-1 protein).

APLP2_MOUSE
NC score	0.039708 (rank : 56)	θ value	3.0926 (rank : 82)
Query Neighborhood Hits	181	Target Neighborhood Hits	186	Shared Neighborhood Hits	14
SwissProt Accessions	Q06335	Gene names	Aplp2
Domain Architecture
Description	Amyloid-like protein 2 precursor (CDEI box-binding protein) (CDEBP).

PENK_HUMAN
NC score	0.038849 (rank : 57)	θ value	1.06291 (rank : 37)
Query Neighborhood Hits	181	Target Neighborhood Hits	29	Shared Neighborhood Hits	2
SwissProt Accessions	P01210	Gene names	PENK
Domain Architecture
Description	Proenkephalin A precursor [Contains: Synenkephalin; Met-enkephalin (Opioid growth factor) (OGF); Met-enkephalin-Arg-Gly-Leu; Leu- enkephalin; Met-enkephalin-Arg-Phe].

OSTP_HUMAN
NC score	0.038791 (rank : 58)	θ value	5.27518 (rank : 120)
Query Neighborhood Hits	181	Target Neighborhood Hits	36	Shared Neighborhood Hits	7
SwissProt Accessions	P10451, Q15681, Q15682, Q15683, Q8NBK2, Q96IZ1	Gene names	SPP1, OPN
Domain Architecture
Description	Osteopontin precursor (Bone sialoprotein-1) (Secreted phosphoprotein 1) (SPP-1) (Urinary stone protein) (Nephropontin) (Uropontin).

CNOT3_HUMAN
NC score	0.038676 (rank : 59)	θ value	2.36792 (rank : 66)
Query Neighborhood Hits	181	Target Neighborhood Hits	425	Shared Neighborhood Hits	23
SwissProt Accessions	O75175, Q9NZN7, Q9UF76	Gene names	CNOT3, KIAA0691, NOT3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

MAGC1_HUMAN
NC score	0.038366 (rank : 60)	θ value	0.47712 (rank : 21)
Query Neighborhood Hits	181	Target Neighborhood Hits	431	Shared Neighborhood Hits	34
SwissProt Accessions	O60732, O75451, Q8TCV4	Gene names	MAGEC1
Domain Architecture
Description	Melanoma-associated antigen C1 (MAGE-C1 antigen) (Cancer-testis antigen CT7).

PGCA_HUMAN
NC score	0.037814 (rank : 61)	θ value	1.81305 (rank : 61)
Query Neighborhood Hits	181	Target Neighborhood Hits	821	Shared Neighborhood Hits	35
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

PPRB_HUMAN
NC score	0.037490 (rank : 62)	θ value	6.88961 (rank : 155)
Query Neighborhood Hits	181	Target Neighborhood Hits	311	Shared Neighborhood Hits	28
SwissProt Accessions	Q15648, O43810, O75447, Q9HD39	Gene names	PPARBP, ARC205, DRIP205, TRAP220, TRIP2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2) (p53 regulatory protein RB18A) (Vitamin D receptor-interacting protein complex component DRIP205) (Activator- recruited cofactor 205 kDa component) (ARC205).

TAU_HUMAN
NC score	0.037254 (rank : 63)	θ value	6.88961 (rank : 157)
Query Neighborhood Hits	181	Target Neighborhood Hits	448	Shared Neighborhood Hits	35
SwissProt Accessions	P10636, P18518, Q14799, Q15549, Q15550, Q15551, Q9UDJ3, Q9UMH0, Q9UQ96	Gene names	MAPT, MTBT1, TAU
Domain Architecture
Description	Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau).

PRGC1_HUMAN
NC score	0.036254 (rank : 64)	θ value	1.06291 (rank : 38)
Query Neighborhood Hits	181	Target Neighborhood Hits	157	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UBK2, Q9UN32	Gene names	PPARGC1A, LEM6, PGC1, PGC1A, PPARGC1
Domain Architecture
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PPAR gamma coactivator 1-alpha) (PPARGC-1-alpha) (PGC-1-alpha) (Ligand effect modulator 6).

K2027_MOUSE
NC score	0.036045 (rank : 65)	θ value	2.36792 (rank : 70)
Query Neighborhood Hits	181	Target Neighborhood Hits	106	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BWS5, Q69Z30	Gene names	Kiaa2027
Domain Architecture	No domain graphic available
Description	Protein KIAA2027.

MBD5_HUMAN
NC score	0.035113 (rank : 66)	θ value	4.03905 (rank : 101)
Query Neighborhood Hits	181	Target Neighborhood Hits	176	Shared Neighborhood Hits	19
SwissProt Accessions	Q9P267, Q9NUV6	Gene names	MBD5, KIAA1461
Domain Architecture	No domain graphic available
Description	Methyl-CpG-binding domain protein 5 (Methyl-CpG-binding protein MBD5).

NFH_MOUSE
NC score	0.034777 (rank : 67)	θ value	5.27518 (rank : 119)
Query Neighborhood Hits	181	Target Neighborhood Hits	2247	Shared Neighborhood Hits	93
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

A4_MOUSE
NC score	0.034663 (rank : 68)	θ value	5.27518 (rank : 109)
Query Neighborhood Hits	181	Target Neighborhood Hits	275	Shared Neighborhood Hits	13
SwissProt Accessions	P12023, P97487, P97942, Q99K32	Gene names	App
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 protein precursor (APP) (ABPP) (Alzheimer disease amyloid protein homolog) (Amyloidogenic glycoprotein) (AG) [Contains: Soluble APP-alpha (S-APP-alpha); Soluble APP-beta (S-APP-beta); C99 (APP-C99); Beta-amyloid protein 42 (Beta-APP42); Beta-amyloid protein 40 (Beta-APP40); C83; P3(42); P3(40); Gamma-CTF(59) (Gamma-secretase C-terminal fragment 59) (Amyloid intracellular domain 59) (AID(59)) (APP-C59); Gamma-CTF(57) (Gamma-secretase C-terminal fragment 57) (Amyloid intracellular domain 57) (AID(57)) (APP-C57); Gamma-CTF(50) (Gamma-secretase C-terminal fragment 50) (Amyloid intracellular domain 50) (AID(50)); C31].

BRD4_HUMAN
NC score	0.034580 (rank : 69)	θ value	6.88961 (rank : 128)
Query Neighborhood Hits	181	Target Neighborhood Hits	851	Shared Neighborhood Hits	40
SwissProt Accessions	O60885, O60433, Q96PD3	Gene names	BRD4, HUNK1
Domain Architecture
Description	Bromodomain-containing protein 4 (HUNK1 protein).

WTAP_MOUSE
NC score	0.034381 (rank : 70)	θ value	2.36792 (rank : 81)
Query Neighborhood Hits	181	Target Neighborhood Hits	250	Shared Neighborhood Hits	8
SwissProt Accessions	Q9ER69	Gene names	Wtap
Domain Architecture	No domain graphic available
Description	Wilms' tumor 1-associating protein (WT1-associated protein) (Putative pre-mRNA-splicing regulator female-lethal(2D) homolog).

TENS1_HUMAN
NC score	0.033912 (rank : 71)	θ value	2.36792 (rank : 79)
Query Neighborhood Hits	181	Target Neighborhood Hits	400	Shared Neighborhood Hits	22
SwissProt Accessions	Q9HBL0	Gene names	TNS1, TNS
Domain Architecture	No domain graphic available
Description	Tensin-1.

CIC_HUMAN
NC score	0.032486 (rank : 72)	θ value	6.88961 (rank : 130)
Query Neighborhood Hits	181	Target Neighborhood Hits	992	Shared Neighborhood Hits	53
SwissProt Accessions	Q96RK0, Q7LGI1, Q9UEG5, Q9Y6T1	Gene names	CIC, KIAA0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CIC_MOUSE
NC score	0.032427 (rank : 73)	θ value	4.03905 (rank : 94)
Query Neighborhood Hits	181	Target Neighborhood Hits	742	Shared Neighborhood Hits	48
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

MLL3_MOUSE
NC score	0.032075 (rank : 74)	θ value	8.99809 (rank : 171)
Query Neighborhood Hits	181	Target Neighborhood Hits	1399	Shared Neighborhood Hits	67
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

NTHL1_HUMAN
NC score	0.031790 (rank : 75)	θ value	6.88961 (rank : 148)
Query Neighborhood Hits	181	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	P78549, Q99566, Q99794, Q9BPX2	Gene names	NTHL1, NTH1, OCTS3
Domain Architecture
Description	Endonuclease III-like protein 1 (EC 4.2.99.18).

SSH2_HUMAN
NC score	0.031035 (rank : 76)	θ value	3.0926 (rank : 89)
Query Neighborhood Hits	181	Target Neighborhood Hits	140	Shared Neighborhood Hits	12
SwissProt Accessions	Q76I76, Q8TDB5, Q8WYL1, Q8WYL2, Q96F40, Q96H36, Q9C0D8	Gene names	SSH2, KIAA1725, SSH2L
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 2 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-2L) (hSSH-2L).

CC47_MOUSE
NC score	0.030927 (rank : 77)	θ value	1.81305 (rank : 58)
Query Neighborhood Hits	181	Target Neighborhood Hits	245	Shared Neighborhood Hits	12
SwissProt Accessions	Q9D024, Q3TSB5, Q3V1S7, Q8C5D9, Q920S6	Gene names	Ccdc47, Asp4
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 47 precursor (Adipocyte-specific protein 4).

3BP2_MOUSE
NC score	0.030837 (rank : 78)	θ value	1.81305 (rank : 56)
Query Neighborhood Hits	181	Target Neighborhood Hits	142	Shared Neighborhood Hits	9
SwissProt Accessions	Q06649	Gene names	Sh3bp2, 3bp2
Domain Architecture
Description	SH3 domain-binding protein 2 (3BP-2).

RBMX2_MOUSE
NC score	0.030407 (rank : 79)	θ value	0.279714 (rank : 16)
Query Neighborhood Hits	181	Target Neighborhood Hits	287	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R0F5, Q3TI42	Gene names	Rbmx2
Domain Architecture
Description	RNA-binding motif protein, X-linked 2.

MAP1A_HUMAN
NC score	0.030383 (rank : 80)	θ value	8.99809 (rank : 170)
Query Neighborhood Hits	181	Target Neighborhood Hits	1626	Shared Neighborhood Hits	62
SwissProt Accessions	P78559, O95643, Q12973, Q15882, Q9UJT4	Gene names	MAP1A
Domain Architecture
Description	Microtubule-associated protein 1A (MAP 1A) (Proliferation-related protein p80) [Contains: MAP1 light chain LC2].

WTAP_HUMAN
NC score	0.030204 (rank : 81)	θ value	4.03905 (rank : 107)
Query Neighborhood Hits	181	Target Neighborhood Hits	262	Shared Neighborhood Hits	8
SwissProt Accessions	Q15007, Q96T28, Q9BYJ7, Q9H4E2	Gene names	WTAP, KIAA0105
Domain Architecture	No domain graphic available
Description	Wilms' tumor 1-associating protein (WT1-associated protein) (Putative pre-mRNA-splicing regulator female-lethal(2D) homolog).

CO039_MOUSE
NC score	0.030100 (rank : 82)	θ value	6.88961 (rank : 132)
Query Neighborhood Hits	181	Target Neighborhood Hits	445	Shared Neighborhood Hits	33
SwissProt Accessions	Q3TEI4, Q3TMF2, Q3U253, Q3UM75, Q9DA93	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf39 homolog.

SETB1_MOUSE
NC score	0.029786 (rank : 83)	θ value	1.38821 (rank : 53)
Query Neighborhood Hits	181	Target Neighborhood Hits	150	Shared Neighborhood Hits	13
SwissProt Accessions	O88974, Q922K1	Gene names	Setdb1, Eset
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

HNRPC_MOUSE
NC score	0.029638 (rank : 84)	θ value	1.06291 (rank : 34)
Query Neighborhood Hits	181	Target Neighborhood Hits	190	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Z204, Q3TLB5, Q501Q3, Q8C2G5, Q99KE2, Q9CQT3, Q9CY83	Gene names	Hnrpc, Hnrnpc
Domain Architecture
Description	Heterogeneous nuclear ribonucleoproteins C1/C2 (hnRNP C1 / hnRNP C2).

KCNQ2_MOUSE
NC score	0.029255 (rank : 85)	θ value	0.0736092 (rank : 10)
Query Neighborhood Hits	181	Target Neighborhood Hits	163	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Z351, Q8R498, Q9QWN9, Q9Z342, Q9Z343, Q9Z344, Q9Z345, Q9Z346, Q9Z347, Q9Z348, Q9Z349, Q9Z350	Gene names	Kcnq2, Kqt2
Domain Architecture
Description	Potassium voltage-gated channel subfamily KQT member 2 (Voltage-gated potassium channel subunit Kv7.2) (Potassium channel subunit alpha KvLQT2) (KQT-like 2).

GTSE1_MOUSE
NC score	0.029193 (rank : 86)	θ value	6.88961 (rank : 139)
Query Neighborhood Hits	181	Target Neighborhood Hits	245	Shared Neighborhood Hits	16
SwissProt Accessions	Q8R080, O89015, Q9CSG9	Gene names	Gtse1, B99
Domain Architecture	No domain graphic available
Description	G2 and S phase expressed protein 1 (Gtse-1) (B99 protein).

CENPC_HUMAN
NC score	0.028543 (rank : 87)	θ value	4.03905 (rank : 91)
Query Neighborhood Hits	181	Target Neighborhood Hits	147	Shared Neighborhood Hits	8
SwissProt Accessions	Q03188, Q9P0M5	Gene names	CENPC1, CENPC, ICEN7
Domain Architecture	No domain graphic available
Description	Centromere protein C 1 (CENP-C) (Centromere autoantigen C) (Interphase centromere complex protein 7).

RFX1_HUMAN
NC score	0.028460 (rank : 88)	θ value	3.0926 (rank : 88)
Query Neighborhood Hits	181	Target Neighborhood Hits	256	Shared Neighborhood Hits	26
SwissProt Accessions	P22670	Gene names	RFX1
Domain Architecture
Description	MHC class II regulatory factor RFX1 (RFX) (Enhancer factor C) (EF-C).

FMNL_HUMAN
NC score	0.028307 (rank : 89)	θ value	1.38821 (rank : 46)
Query Neighborhood Hits	181	Target Neighborhood Hits	529	Shared Neighborhood Hits	27
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

ANK3_HUMAN
NC score	0.027805 (rank : 90)	θ value	0.00509761 (rank : 6)
Query Neighborhood Hits	181	Target Neighborhood Hits	853	Shared Neighborhood Hits	28
SwissProt Accessions	Q12955	Gene names	ANK3
Domain Architecture
Description	Ankyrin-3 (ANK-3) (Ankyrin-G).

MTSS1_MOUSE
NC score	0.027395 (rank : 91)	θ value	6.88961 (rank : 144)
Query Neighborhood Hits	181	Target Neighborhood Hits	592	Shared Neighborhood Hits	36
SwissProt Accessions	Q8R1S4, Q8BMM3, Q99LB3	Gene names	Mtss1, Mim
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein).

PPR3A_MOUSE
NC score	0.027113 (rank : 92)	θ value	2.36792 (rank : 77)
Query Neighborhood Hits	181	Target Neighborhood Hits	45	Shared Neighborhood Hits	3
SwissProt Accessions	Q99MR9, Q8BUJ4, Q8BUL0	Gene names	Ppp1r3a, Pp1g
Domain Architecture	No domain graphic available
Description	Protein phosphatase 1 regulatory subunit 3A (Protein phosphatase 1 glycogen-associated regulatory subunit) (Protein phosphatase type-1 glycogen targeting subunit) (RGL).

NCOAT_MOUSE
NC score	0.026709 (rank : 93)	θ value	2.36792 (rank : 75)
Query Neighborhood Hits	181	Target Neighborhood Hits	43	Shared Neighborhood Hits	3
SwissProt Accessions	Q9EQQ9, Q3ULY7, Q6ZQ71, Q8BK05, Q8BTT2, Q8CFX2, Q9CSJ4, Q9CUR7	Gene names	Mgea5, Hexc, Kiaa0679
Domain Architecture	No domain graphic available
Description	Bifunctional protein NCOAT (Nuclear cytoplasmic O-GlcNAcase and acetyltransferase) (Meningioma-expressed antigen 5) [Includes: Beta- hexosaminidase (EC 3.2.1.52) (N-acetyl-beta-glucosaminidase) (Beta-N- acetylhexosaminidase) (Hexosaminidase C) (N-acetyl-beta-D- glucosaminidase) (O-GlcNAcase); Histone acetyltransferase (EC 2.3.1.48) (HAT)].

LR37B_HUMAN
NC score	0.025728 (rank : 94)	θ value	1.81305 (rank : 59)
Query Neighborhood Hits	181	Target Neighborhood Hits	392	Shared Neighborhood Hits	23
SwissProt Accessions	Q96QE4, Q5YKG6	Gene names	LRRC37B
Domain Architecture	No domain graphic available
Description	Leucine-rich repeat-containing protein 37B precursor (C66 SLIT-like testicular protein).

CENPC_MOUSE
NC score	0.025172 (rank : 95)	θ value	8.99809 (rank : 164)
Query Neighborhood Hits	181	Target Neighborhood Hits	154	Shared Neighborhood Hits	12
SwissProt Accessions	P49452	Gene names	Cenpc1, Cenpc
Domain Architecture	No domain graphic available
Description	Centromere protein C 1 (CENP-C) (Centromere autoantigen C).

PCX1_HUMAN
NC score	0.025167 (rank : 96)	θ value	6.88961 (rank : 150)
Query Neighborhood Hits	181	Target Neighborhood Hits	102	Shared Neighborhood Hits	9
SwissProt Accessions	Q96RV3, O94897, Q96AI7, Q9Y2J9	Gene names	PCNX, KIAA0805, KIAA0995, PCNXL1
Domain Architecture
Description	Pecanex-like protein 1 (Pecanex homolog).

COHA1_MOUSE
NC score	0.024602 (rank : 97)	θ value	6.88961 (rank : 133)
Query Neighborhood Hits	181	Target Neighborhood Hits	414	Shared Neighborhood Hits	28
SwissProt Accessions	Q07563, Q99LK8	Gene names	Col17a1, Bp180, Bpag2
Domain Architecture
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

COHA1_HUMAN
NC score	0.023878 (rank : 98)	θ value	5.27518 (rank : 117)
Query Neighborhood Hits	181	Target Neighborhood Hits	400	Shared Neighborhood Hits	31
SwissProt Accessions	Q9UMD9, Q02802, Q99018, Q9NQK9, Q9UC14	Gene names	COL17A1, BP180, BPAG2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

TREF1_MOUSE
NC score	0.023674 (rank : 99)	θ value	1.38821 (rank : 55)
Query Neighborhood Hits	181	Target Neighborhood Hits	682	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BXJ2, Q6PCQ4, Q80X25, Q810H8, Q8BY31	Gene names	Trerf1
Domain Architecture	No domain graphic available
Description	Transcriptional-regulating factor 1 (Transcriptional-regulating protein 132) (Zinc finger transcription factor TReP-132).

FXL19_HUMAN
NC score	0.023541 (rank : 100)	θ value	2.36792 (rank : 69)
Query Neighborhood Hits	181	Target Neighborhood Hits	147	Shared Neighborhood Hits	8
SwissProt Accessions	Q6PCT2, Q8N789, Q9NT14	Gene names	FBXL19, FBL19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

INPP_HUMAN
NC score	0.023106 (rank : 101)	θ value	4.03905 (rank : 99)
Query Neighborhood Hits	181	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	P49441	Gene names	INPP1
Domain Architecture
Description	Inositol polyphosphate 1-phosphatase (EC 3.1.3.57) (IPPase) (IPP).

ST5_MOUSE
NC score	0.023102 (rank : 102)	θ value	1.06291 (rank : 39)
Query Neighborhood Hits	181	Target Neighborhood Hits	126	Shared Neighborhood Hits	10
SwissProt Accessions	Q924W7, Q78H54, Q8K2P3, Q924W8	Gene names	St5, Dennd2b
Domain Architecture	No domain graphic available
Description	Suppression of tumorigenicity 5 (DENN domain-containing protein 2B).

TACC3_HUMAN
NC score	0.022726 (rank : 103)	θ value	5.27518 (rank : 125)
Query Neighborhood Hits	181	Target Neighborhood Hits	779	Shared Neighborhood Hits	31
SwissProt Accessions	Q9Y6A5, Q9UMQ1	Gene names	TACC3, ERIC1
Domain Architecture
Description	Transforming acidic coiled-coil-containing protein 3 (ERIC-1).

CN044_MOUSE
NC score	0.022531 (rank : 104)	θ value	8.99809 (rank : 166)
Query Neighborhood Hits	181	Target Neighborhood Hits	57	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CB59, Q8BQX8, Q8BSL9, Q8CBZ3	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf44 homolog.

ARI4A_HUMAN
NC score	0.022331 (rank : 105)	θ value	8.99809 (rank : 161)
Query Neighborhood Hits	181	Target Neighborhood Hits	434	Shared Neighborhood Hits	22
SwissProt Accessions	P29374, Q15991, Q15992, Q15993	Gene names	ARID4A, RBBP1, RBP1
Domain Architecture
Description	AT-rich interactive domain-containing protein 4A (ARID domain- containing protein 4A) (Retinoblastoma-binding protein 1) (RBBP-1).

CJ047_MOUSE
NC score	0.021827 (rank : 106)	θ value	8.99809 (rank : 165)
Query Neighborhood Hits	181	Target Neighborhood Hits	76	Shared Neighborhood Hits	7
SwissProt Accessions	Q8C5R2, Q8R017, Q8R2Z9	Gene names
Domain Architecture	No domain graphic available
Description	Protein C10orf47 homolog.

FGD1_MOUSE
NC score	0.021639 (rank : 107)	θ value	0.813845 (rank : 30)
Query Neighborhood Hits	181	Target Neighborhood Hits	387	Shared Neighborhood Hits	20
SwissProt Accessions	P52734	Gene names	Fgd1
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein homolog) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

SYTL2_HUMAN
NC score	0.021435 (rank : 108)	θ value	1.06291 (rank : 40)
Query Neighborhood Hits	181	Target Neighborhood Hits	248	Shared Neighborhood Hits	10
SwissProt Accessions	Q9HCH5, Q2YDA7, Q8ND34, Q96BJ2, Q9H768, Q9NXM1	Gene names	SYTL2, KIAA1597, SLP2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

MAFB_MOUSE
NC score	0.021235 (rank : 109)	θ value	2.36792 (rank : 73)
Query Neighborhood Hits	181	Target Neighborhood Hits	92	Shared Neighborhood Hits	5
SwissProt Accessions	P54841	Gene names	Mafb, Krml, Maf1
Domain Architecture
Description	Transcription factor MafB (V-maf musculoaponeurotic fibrosarcoma oncogene homolog B) (Transcription factor MAF1) (Segmentation protein KR) (Kreisler).

HUWE1_HUMAN
NC score	0.020928 (rank : 110)	θ value	1.38821 (rank : 47)
Query Neighborhood Hits	181	Target Neighborhood Hits	443	Shared Neighborhood Hits	25
SwissProt Accessions	Q7Z6Z7, O15029, Q4G2Z2, Q5H961, Q6P4D0, Q8NG67, Q9BUI0, Q9HCJ4, Q9NSL6, Q9P0A9	Gene names	HUWE1, KIAA0312, KIAA1578, UREB1
Domain Architecture	No domain graphic available
Description	HECT, UBA and WWE domain-containing protein 1 (EC 6.3.2.-) (E3 ubiquitin protein ligase URE-B1) (Mcl-1 ubiquitin ligase E3) (Mule) (ARF-binding protein 1) (ARF-BP1).

SKI_MOUSE
NC score	0.020610 (rank : 111)	θ value	2.36792 (rank : 78)
Query Neighborhood Hits	181	Target Neighborhood Hits	423	Shared Neighborhood Hits	14
SwissProt Accessions	Q60698, Q8VIL5	Gene names	Ski
Domain Architecture	No domain graphic available
Description	Ski oncogene (C-ski).

CN044_HUMAN
NC score	0.020337 (rank : 112)	θ value	6.88961 (rank : 131)
Query Neighborhood Hits	181	Target Neighborhood Hits	227	Shared Neighborhood Hits	8
SwissProt Accessions	Q96MY7	Gene names	C14orf44
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C14orf44.

P73L_HUMAN
NC score	0.020056 (rank : 113)	θ value	4.03905 (rank : 104)
Query Neighborhood Hits	181	Target Neighborhood Hits	102	Shared Neighborhood Hits	14
SwissProt Accessions	Q9H3D4, O75080, O75195, O75922, O76078, Q6VEG2, Q6VEG3, Q6VEG4, Q6VFJ1, Q6VFJ2, Q6VFJ3, Q6VH20, Q7LDI3, Q7LDI4, Q7LDI5, Q96KR0, Q9H3D2, Q9H3D3, Q9H3P8, Q9NPH7, Q9P1B4, Q9P1B5, Q9P1B6, Q9P1B7, Q9UBV9, Q9UE10, Q9UP26, Q9UP27, Q9UP28, Q9UP74	Gene names	TP73L, KET, P63, P73H, P73L
Domain Architecture	No domain graphic available
Description	Tumor protein p73-like (p73L) (p63) (Tumor protein 63) (TP63) (p51) (p40) (Keratinocyte transcription factor KET) (Chronic ulcerative stomatitis protein) (CUSP).

FXL19_MOUSE
NC score	0.020030 (rank : 114)	θ value	5.27518 (rank : 118)
Query Neighborhood Hits	181	Target Neighborhood Hits	217	Shared Neighborhood Hits	10
SwissProt Accessions	Q6PB97, Q7TSH0, Q8BIB4	Gene names	Fbxl19
Domain Architecture	No domain graphic available
Description	F-box/LRR-repeat protein 19 (F-box and leucine-rich repeat protein 19).

TPR_HUMAN
NC score	0.019198 (rank : 115)	θ value	0.62314 (rank : 27)
Query Neighborhood Hits	181	Target Neighborhood Hits	1921	Shared Neighborhood Hits	44
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

HXA11_HUMAN
NC score	0.018750 (rank : 116)	θ value	1.06291 (rank : 35)
Query Neighborhood Hits	181	Target Neighborhood Hits	334	Shared Neighborhood Hits	4
SwissProt Accessions	P31270	Gene names	HOXA11, HOX1I
Domain Architecture
Description	Homeobox protein Hox-A11 (Hox-1I).

TCAL5_HUMAN
NC score	0.018504 (rank : 117)	θ value	8.99809 (rank : 180)
Query Neighborhood Hits	181	Target Neighborhood Hits	806	Shared Neighborhood Hits	37
SwissProt Accessions	Q5H9L2	Gene names	TCEAL5
Domain Architecture	No domain graphic available
Description	Transcription elongation factor A protein-like 5 (TCEA-like protein 5) (Transcription elongation factor S-II protein-like 5).

OBFC1_MOUSE
NC score	0.018467 (rank : 118)	θ value	6.88961 (rank : 149)
Query Neighborhood Hits	181	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	Q8K2X3, Q8C6I6	Gene names	Obfc1
Domain Architecture	No domain graphic available
Description	Oligonucleotide/oligosaccharide-binding fold-containing protein 1.

AB1IP_MOUSE
NC score	0.018413 (rank : 119)	θ value	5.27518 (rank : 110)
Query Neighborhood Hits	181	Target Neighborhood Hits	181	Shared Neighborhood Hits	10
SwissProt Accessions	Q8R5A3, O35329, Q8BRU0, Q99KV8	Gene names	Apbb1ip, Prel1
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family B member 1- interacting protein (APBB1-interacting protein 1) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 48).

CO3A1_HUMAN
NC score	0.017875 (rank : 120)	θ value	3.0926 (rank : 83)
Query Neighborhood Hits	181	Target Neighborhood Hits	452	Shared Neighborhood Hits	27
SwissProt Accessions	P02461, Q15112, Q16403, Q6LDB3, Q6LDJ2, Q6LDJ3, Q7KZ56	Gene names	COL3A1
Domain Architecture
Description	Collagen alpha-1(III) chain precursor.

FGD1_HUMAN
NC score	0.017735 (rank : 121)	θ value	4.03905 (rank : 95)
Query Neighborhood Hits	181	Target Neighborhood Hits	367	Shared Neighborhood Hits	22
SwissProt Accessions	P98174, Q8N4D9	Gene names	FGD1, ZFYVE3
Domain Architecture
Description	FYVE, RhoGEF and PH domain-containing protein 1 (Faciogenital dysplasia 1 protein) (Zinc finger FYVE domain-containing protein 3) (Rho/Rac guanine nucleotide exchange factor FGD1) (Rho/Rac GEF).

KIF17_MOUSE
NC score	0.017469 (rank : 122)	θ value	0.62314 (rank : 25)
Query Neighborhood Hits	181	Target Neighborhood Hits	452	Shared Neighborhood Hits	16
SwissProt Accessions	Q99PW8	Gene names	Kif17
Domain Architecture
Description	Kinesin-like protein KIF17 (MmKIF17).

RTN1_MOUSE
NC score	0.017207 (rank : 123)	θ value	5.27518 (rank : 124)
Query Neighborhood Hits	181	Target Neighborhood Hits	189	Shared Neighborhood Hits	13
SwissProt Accessions	Q8K0T0, Q8K4S4	Gene names	Rtn1, Nsp
Domain Architecture	No domain graphic available
Description	Reticulon-1 (Neuroendocrine-specific protein).

CCD60_HUMAN
NC score	0.017180 (rank : 124)	θ value	6.88961 (rank : 129)
Query Neighborhood Hits	181	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IWA6	Gene names	CCDC60
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 60.

ELK3_MOUSE
NC score	0.017051 (rank : 125)	θ value	1.38821 (rank : 45)
Query Neighborhood Hits	181	Target Neighborhood Hits	72	Shared Neighborhood Hits	4
SwissProt Accessions	P41971, P97747, Q62346	Gene names	Elk3, Erp, Net
Domain Architecture
Description	ETS domain-containing protein Elk-3 (ETS-related protein NET) (ETS- related protein ERP).

FOLC_MOUSE
NC score	0.016482 (rank : 126)	θ value	6.88961 (rank : 137)
Query Neighborhood Hits	181	Target Neighborhood Hits	11	Shared Neighborhood Hits	2
SwissProt Accessions	P48760	Gene names	Fpgs
Domain Architecture
Description	Folylpolyglutamate synthase, mitochondrial precursor (EC 6.3.2.17) (Folylpoly-gamma-glutamate synthetase) (FPGS) (Tetrahydrofolate synthase) (Tetrahydrofolylpolyglutamate synthase).

BSND_MOUSE
NC score	0.016260 (rank : 127)	θ value	8.99809 (rank : 162)
Query Neighborhood Hits	181	Target Neighborhood Hits	12	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VIM4, Q8C740, Q8CHY0	Gene names	Bsnd
Domain Architecture	No domain graphic available
Description	Barttin.

TF3C2_MOUSE
NC score	0.016059 (rank : 128)	θ value	6.88961 (rank : 158)
Query Neighborhood Hits	181	Target Neighborhood Hits	165	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BL74, Q3U7Z9, Q80XQ7, Q8BJJ4, Q8BLP3, Q8K1J1, Q9CSS0, Q9CVE6, Q9DBK6	Gene names	Gtf3c2, Kiaa0011
Domain Architecture
Description	General transcription factor 3C polypeptide 2 (Transcription factor IIIC-subunit beta) (TF3C-beta) (TFIIIC 110 kDa subunit) (TFIIIC110).

CO7A1_HUMAN
NC score	0.014967 (rank : 129)	θ value	2.36792 (rank : 67)
Query Neighborhood Hits	181	Target Neighborhood Hits	807	Shared Neighborhood Hits	33
SwissProt Accessions	Q02388, Q14054, Q16507	Gene names	COL7A1
Domain Architecture
Description	Collagen alpha-1(VII) chain precursor (Long-chain collagen) (LC collagen).

HXA11_MOUSE
NC score	0.014956 (rank : 130)	θ value	1.06291 (rank : 36)
Query Neighborhood Hits	181	Target Neighborhood Hits	327	Shared Neighborhood Hits	3
SwissProt Accessions	P31311, Q3V026	Gene names	Hoxa11, Hox-1.9, Hoxa-11
Domain Architecture
Description	Homeobox protein Hox-A11 (Hox-1.9).

CB013_MOUSE
NC score	0.014700 (rank : 131)	θ value	8.99809 (rank : 163)
Query Neighborhood Hits	181	Target Neighborhood Hits	43	Shared Neighborhood Hits	4
SwissProt Accessions	Q9D842, Q8BZL5, Q99LX6	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C2orf13 homolog.

ELL_HUMAN
NC score	0.014357 (rank : 132)	θ value	8.99809 (rank : 167)
Query Neighborhood Hits	181	Target Neighborhood Hits	183	Shared Neighborhood Hits	13
SwissProt Accessions	P55199	Gene names	ELL, C19orf17
Domain Architecture
Description	RNA polymerase II elongation factor ELL (Eleven-nineteen lysine-rich leukemia protein).

PKHA3_HUMAN
NC score	0.014156 (rank : 133)	θ value	6.88961 (rank : 154)
Query Neighborhood Hits	181	Target Neighborhood Hits	66	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HB20, Q86TQ1, Q9NXT3	Gene names	PLEKHA3, FAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 3 (Phosphoinositol 4-phosphate adaptor protein 1) (FAPP-1).

SAMD4_HUMAN
NC score	0.013862 (rank : 134)	θ value	8.99809 (rank : 177)
Query Neighborhood Hits	181	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UPU9	Gene names	SAMD4, KIAA1053
Domain Architecture
Description	Sterile alpha motif domain-containing protein 4.

PIWL1_MOUSE
NC score	0.013779 (rank : 135)	θ value	5.27518 (rank : 122)
Query Neighborhood Hits	181	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	Q9JMB7	Gene names	Piwil1, Miwi
Domain Architecture	No domain graphic available
Description	Piwi-like protein 1.

PIWL1_HUMAN
NC score	0.013709 (rank : 136)	θ value	5.27518 (rank : 121)
Query Neighborhood Hits	181	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	Q96J94, O95404, Q8NA60, Q8TBY5, Q96JD5	Gene names	PIWIL1, HIWI
Domain Architecture	No domain graphic available
Description	Piwi-like protein 1.

ATF7_MOUSE
NC score	0.013660 (rank : 137)	θ value	6.88961 (rank : 127)
Query Neighborhood Hits	181	Target Neighborhood Hits	286	Shared Neighborhood Hits	10
SwissProt Accessions	Q8R0S1	Gene names	Atf7
Domain Architecture	No domain graphic available
Description	Cyclic AMP-dependent transcription factor ATF-7 (Activating transcription factor 7) (Transcription factor ATF-A).

EYA3_HUMAN
NC score	0.013572 (rank : 138)	θ value	6.88961 (rank : 135)
Query Neighborhood Hits	181	Target Neighborhood Hits	45	Shared Neighborhood Hits	5
SwissProt Accessions	Q99504, O95463, Q99813	Gene names	EYA3
Domain Architecture
Description	Eyes absent homolog 3 (EC 3.1.3.48).

TLR2_HUMAN
NC score	0.013531 (rank : 139)	θ value	1.38821 (rank : 54)
Query Neighborhood Hits	181	Target Neighborhood Hits	290	Shared Neighborhood Hits	5
SwissProt Accessions	O60603, O15454, Q8NI00	Gene names	TLR2, TIL4
Domain Architecture
Description	Toll-like receptor 2 precursor (Toll/interleukin 1 receptor-like protein 4) (CD282 antigen).

EYA3_MOUSE
NC score	0.013291 (rank : 140)	θ value	6.88961 (rank : 136)
Query Neighborhood Hits	181	Target Neighborhood Hits	21	Shared Neighborhood Hits	3
SwissProt Accessions	P97480, P97768	Gene names	Eya3
Domain Architecture
Description	Eyes absent homolog 3 (EC 3.1.3.48).

BPAEA_MOUSE
NC score	0.013265 (rank : 141)	θ value	1.38821 (rank : 44)
Query Neighborhood Hits	181	Target Neighborhood Hits	1480	Shared Neighborhood Hits	27
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

AGGF1_HUMAN
NC score	0.013116 (rank : 142)	θ value	8.99809 (rank : 160)
Query Neighborhood Hits	181	Target Neighborhood Hits	271	Shared Neighborhood Hits	10
SwissProt Accessions	Q8N302, O00581, Q53YS3, Q9BU84, Q9NW66	Gene names	AGGF1, VG5Q
Domain Architecture
Description	Angiogenic factor with G patch and FHA domains 1 (Angiogenic factor VG5Q) (Vasculogenesis gene on 5q protein) (hVG5Q).

SOS1_MOUSE
NC score	0.012920 (rank : 143)	θ value	6.88961 (rank : 156)
Query Neighborhood Hits	181	Target Neighborhood Hits	281	Shared Neighborhood Hits	12
SwissProt Accessions	Q62245, Q62244	Gene names	Sos1
Domain Architecture
Description	Son of sevenless homolog 1 (SOS-1) (mSOS-1).

DOCK2_MOUSE
NC score	0.012758 (rank : 144)	θ value	3.0926 (rank : 84)
Query Neighborhood Hits	181	Target Neighborhood Hits	104	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C3J5, Q99M79	Gene names	Dock2
Domain Architecture
Description	Dedicator of cytokinesis protein 2 (Hch protein).

ABP1_HUMAN
NC score	0.012744 (rank : 145)	θ value	5.27518 (rank : 111)
Query Neighborhood Hits	181	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	P19801, Q16683, Q16684, Q56II4, Q6GU42	Gene names	ABP1, AOC1, DAO1
Domain Architecture
Description	Amiloride-sensitive amine oxidase [copper-containing] precursor (EC 1.4.3.6) (Diamine oxidase) (DAO) (Amiloride-binding protein) (ABP) (Histaminase) (Kidney amine oxidase) (KAO).

STA13_MOUSE
NC score	0.012483 (rank : 146)	θ value	3.0926 (rank : 90)
Query Neighborhood Hits	181	Target Neighborhood Hits	89	Shared Neighborhood Hits	4
SwissProt Accessions	Q923Q2, Q8K369	Gene names	Stard13
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13).

KI13B_HUMAN
NC score	0.012382 (rank : 147)	θ value	6.88961 (rank : 141)
Query Neighborhood Hits	181	Target Neighborhood Hits	492	Shared Neighborhood Hits	20
SwissProt Accessions	Q9NQT8, O75134, Q9BYJ6	Gene names	KIF13B, GAKIN, KIAA0639
Domain Architecture
Description	Kinesin-like protein KIF13B (Kinesin-like protein GAKIN).

PPGB_HUMAN
NC score	0.012033 (rank : 148)	θ value	8.99809 (rank : 175)
Query Neighborhood Hits	181	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	P10619, Q5JZH1, Q96KJ2, Q9BR08, Q9BW68	Gene names	PPGB
Domain Architecture
Description	Lysosomal protective protein precursor (EC 3.4.16.5) (Cathepsin A) (Carboxypeptidase C) (Protective protein for beta-galactosidase) [Contains: Lysosomal protective protein 32 kDa chain; Lysosomal protective protein 20 kDa chain].

NCOA3_HUMAN
NC score	0.011913 (rank : 149)	θ value	6.88961 (rank : 147)
Query Neighborhood Hits	181	Target Neighborhood Hits	171	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y6Q9, Q5JYD9, Q5JYE0, Q9BR49, Q9UPC9, Q9UPG4, Q9UPG7	Gene names	NCOA3, AIB1, RAC3, TRAM1
Domain Architecture
Description	Nuclear receptor coactivator 3 (EC 2.3.1.48) (NCoA-3) (Thyroid hormone receptor activator molecule 1) (TRAM-1) (ACTR) (Receptor-associated coactivator 3) (RAC-3) (Amplified in breast cancer-1 protein) (AIB-1) (Steroid receptor coactivator protein 3) (SRC-3) (CBP-interacting protein) (pCIP).

DSCL1_HUMAN
NC score	0.011836 (rank : 150)	θ value	0.813845 (rank : 29)
Query Neighborhood Hits	181	Target Neighborhood Hits	589	Shared Neighborhood Hits	15
SwissProt Accessions	Q8TD84, Q76MU9, Q8IZY3, Q8IZY4, Q8WXU7, Q9ULT7	Gene names	DSCAML1, DSCAM2, KIAA1132
Domain Architecture	No domain graphic available
Description	Down syndrome cell adhesion molecule-like protein 1 precursor (Down syndrome cell adhesion molecule 2).

TRI36_HUMAN
NC score	0.011832 (rank : 151)	θ value	2.36792 (rank : 80)
Query Neighborhood Hits	181	Target Neighborhood Hits	282	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NQ86	Gene names	TRIM36, RBCC728, RNF98
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 36 (Zinc-binding protein Rbcc728) (RING finger protein 98).

MACF1_MOUSE
NC score	0.011517 (rank : 152)	θ value	2.36792 (rank : 72)
Query Neighborhood Hits	181	Target Neighborhood Hits	1313	Shared Neighborhood Hits	28
SwissProt Accessions	Q9QXZ0, P97394, P97395, P97396	Gene names	Macf1, Acf7, Aclp7, Macf
Domain Architecture
Description	Microtubule-actin cross-linking factor 1 (Actin cross-linking family 7).

KIF1C_HUMAN
NC score	0.011112 (rank : 153)	θ value	6.88961 (rank : 142)
Query Neighborhood Hits	181	Target Neighborhood Hits	128	Shared Neighborhood Hits	6
SwissProt Accessions	O43896, O75186	Gene names	KIF1C, KIAA0706
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF1C.

KIF1C_MOUSE
NC score	0.010955 (rank : 154)	θ value	6.88961 (rank : 143)
Query Neighborhood Hits	181	Target Neighborhood Hits	171	Shared Neighborhood Hits	8
SwissProt Accessions	O35071, Q5SX62	Gene names	Kif1c
Domain Architecture	No domain graphic available
Description	Kinesin-like protein KIF1C.

CEP63_HUMAN
NC score	0.010904 (rank : 155)	θ value	4.03905 (rank : 92)
Query Neighborhood Hits	181	Target Neighborhood Hits	1005	Shared Neighborhood Hits	21
SwissProt Accessions	Q96MT8, Q96CR0, Q9H8F5, Q9H8N0	Gene names	CEP63
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 63 kDa (Cep63 protein).

BMP2K_HUMAN
NC score	0.010697 (rank : 156)	θ value	1.81305 (rank : 57)
Query Neighborhood Hits	181	Target Neighborhood Hits	867	Shared Neighborhood Hits	19
SwissProt Accessions	Q9NSY1, O94791, Q8IYF2, Q8N2G7, Q8NHG9, Q9NTG8	Gene names	BMP2K, BIKE
Domain Architecture
Description	BMP-2-inducible protein kinase (EC 2.7.11.1) (BIKe).

LIMA1_HUMAN
NC score	0.010638 (rank : 157)	θ value	8.99809 (rank : 169)
Query Neighborhood Hits	181	Target Neighborhood Hits	309	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UHB6, Q2TAN7, Q9BVF2, Q9H8J1, Q9HBN5, Q9NX96, Q9NXC3, Q9NXU6, Q9P0H8, Q9UHB5	Gene names	LIMA1, EPLIN, SREBP3
Domain Architecture
Description	LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm).

PHLPP_HUMAN
NC score	0.010621 (rank : 158)	θ value	6.88961 (rank : 152)
Query Neighborhood Hits	181	Target Neighborhood Hits	604	Shared Neighborhood Hits	18
SwissProt Accessions	O60346, Q641Q7, Q6P4C4, Q6PJI6, Q86TN6, Q96FK2, Q9NUY1	Gene names	PHLPP, KIAA0606, PLEKHE1, SCOP
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP).

CHD8_HUMAN
NC score	0.010530 (rank : 159)	θ value	4.03905 (rank : 93)
Query Neighborhood Hits	181	Target Neighborhood Hits	235	Shared Neighborhood Hits	15
SwissProt Accessions	Q9HCK8, Q68DQ0, Q8N3Z9, Q8NCY4, Q8TBR9, Q96F26	Gene names	CHD8, HELSNF1, KIAA1564
Domain Architecture	No domain graphic available
Description	Chromodomain-helicase-DNA-binding protein 8 (EC 3.6.1.-) (ATP- dependent helicase CHD8) (CHD-8) (Helicase with SNF2 domain 1).

SMC3_MOUSE
NC score	0.010432 (rank : 160)	θ value	8.99809 (rank : 179)
Query Neighborhood Hits	181	Target Neighborhood Hits	1187	Shared Neighborhood Hits	23
SwissProt Accessions	Q9CW03, O35667, Q9QUS3	Gene names	Cspg6, Bam, Bmh, Mmip1, Smc3, Smc3l1, Smcd
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome segregation protein SmcD) (Bamacan) (Basement membrane-associated chondroitin proteoglycan) (Mad member- interacting protein 1).

SMC3_HUMAN
NC score	0.010387 (rank : 161)	θ value	8.99809 (rank : 178)
Query Neighborhood Hits	181	Target Neighborhood Hits	1186	Shared Neighborhood Hits	23
SwissProt Accessions	Q9UQE7, O60464	Gene names	CSPG6, BAM, BMH, SMC3, SMC3L1
Domain Architecture
Description	Structural maintenance of chromosome 3 (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP) (Bamacan) (Basement membrane-associated chondroitin proteoglycan).

ANR35_HUMAN
NC score	0.010109 (rank : 162)	θ value	5.27518 (rank : 113)
Query Neighborhood Hits	181	Target Neighborhood Hits	784	Shared Neighborhood Hits	14
SwissProt Accessions	Q8N283, Q3MJ10, Q96LS3	Gene names	ANKRD35
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 35.

PER3_MOUSE
NC score	0.009930 (rank : 163)	θ value	6.88961 (rank : 151)
Query Neighborhood Hits	181	Target Neighborhood Hits	85	Shared Neighborhood Hits	3
SwissProt Accessions	O70361	Gene names	Per3
Domain Architecture
Description	Period circadian protein 3 (mPER3).

TTLL4_HUMAN
NC score	0.009917 (rank : 164)	θ value	8.99809 (rank : 181)
Query Neighborhood Hits	181	Target Neighborhood Hits	79	Shared Neighborhood Hits	9
SwissProt Accessions	Q14679, Q8WW29	Gene names	TTLL4, KIAA0173
Domain Architecture
Description	Tubulin--tyrosine ligase-like protein 4.

GRIP1_MOUSE
NC score	0.009710 (rank : 165)	θ value	6.88961 (rank : 138)
Query Neighborhood Hits	181	Target Neighborhood Hits	241	Shared Neighborhood Hits	4
SwissProt Accessions	Q925T6, Q8BLQ3, Q8C0T3, Q925T5, Q925T7	Gene names	Grip1
Domain Architecture
Description	Glutamate receptor-interacting protein 1 (GRIP1 protein).

BMP2K_MOUSE
NC score	0.009471 (rank : 166)	θ value	5.27518 (rank : 114)
Query Neighborhood Hits	181	Target Neighborhood Hits	874	Shared Neighborhood Hits	18
SwissProt Accessions	Q91Z96, Q8C8L7	Gene names	Bmp2k, Bike
Domain Architecture
Description	BMP-2-inducible protein kinase (EC 2.7.11.1) (BIKe).

PHLPP_MOUSE
NC score	0.008948 (rank : 167)	θ value	6.88961 (rank : 153)
Query Neighborhood Hits	181	Target Neighborhood Hits	394	Shared Neighborhood Hits	11
SwissProt Accessions	Q8CHE4, Q6PCN0, Q8QZU8, Q8R5E5, Q99KL6	Gene names	Phlpp, Kiaa0606, Plekhe1, Scop
Domain Architecture	No domain graphic available
Description	PH domain leucine-rich repeat-containing protein phosphatase (EC 3.1.3.16) (PH domain leucine-rich repeat protein phosphatase) (Pleckstrin homology domain-containing family E protein 1) (Suprachiasmatic nucleus circadian oscillatory protein).

PRDM2_HUMAN
NC score	0.008436 (rank : 168)	θ value	8.99809 (rank : 176)
Query Neighborhood Hits	181	Target Neighborhood Hits	1135	Shared Neighborhood Hits	34
SwissProt Accessions	Q13029, Q13149, Q14550, Q5VUL9	Gene names	PRDM2, RIZ
Domain Architecture
Description	PR domain zinc finger protein 2 (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc-finger protein) (Zinc finger protein RIZ) (MTE-binding protein) (MTB-ZF) (GATA-3-binding protein G3B).

GAK_MOUSE
NC score	0.008422 (rank : 169)	θ value	4.03905 (rank : 96)
Query Neighborhood Hits	181	Target Neighborhood Hits	964	Shared Neighborhood Hits	21
SwissProt Accessions	Q99KY4, Q6P1I8, Q6P9S5, Q8BM74, Q8K0Q4	Gene names	Gak
Domain Architecture	No domain graphic available
Description	Cyclin G-associated kinase (EC 2.7.11.1).

NFIB_HUMAN
NC score	0.008189 (rank : 170)	θ value	8.99809 (rank : 173)
Query Neighborhood Hits	181	Target Neighborhood Hits	66	Shared Neighborhood Hits	5
SwissProt Accessions	O00712, O00166, Q12858, Q96J45	Gene names	NFIB
Domain Architecture
Description	Nuclear factor 1 B-type (Nuclear factor 1/B) (NF1-B) (NFI-B) (NF-I/B) (CCAAT-box-binding transcription factor) (CTF) (TGGCA-binding protein).

CP135_HUMAN
NC score	0.008081 (rank : 171)	θ value	6.88961 (rank : 134)
Query Neighborhood Hits	181	Target Neighborhood Hits	1290	Shared Neighborhood Hits	23
SwissProt Accessions	Q66GS9, O75130, Q9H8H7	Gene names	CEP135, CEP4, KIAA0635
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 135 kDa (Cep135 protein) (Centrosomal protein 4).

MYPC3_MOUSE
NC score	0.007822 (rank : 172)	θ value	6.88961 (rank : 146)
Query Neighborhood Hits	181	Target Neighborhood Hits	310	Shared Neighborhood Hits	6
SwissProt Accessions	O70468, O88997	Gene names	Mybpc3
Domain Architecture
Description	Myosin-binding protein C, cardiac-type (Cardiac MyBP-C) (C-protein, cardiac muscle isoform).

ITB4_HUMAN
NC score	0.006923 (rank : 173)	θ value	6.88961 (rank : 140)
Query Neighborhood Hits	181	Target Neighborhood Hits	458	Shared Neighborhood Hits	12
SwissProt Accessions	P16144, O14690, O14691, O15339, O15340, O15341, Q9UIQ4	Gene names	ITGB4
Domain Architecture
Description	Integrin beta-4 precursor (GP150) (CD104 antigen).

PPE2_MOUSE
NC score	0.006908 (rank : 174)	θ value	8.99809 (rank : 174)
Query Neighborhood Hits	181	Target Neighborhood Hits	112	Shared Neighborhood Hits	2
SwissProt Accessions	O35385	Gene names	Ppef2
Domain Architecture
Description	Serine/threonine-protein phosphatase with EF-hands 2 (EC 3.1.3.16) (PPEF-2).

GLI2_HUMAN
NC score	0.006712 (rank : 175)	θ value	4.03905 (rank : 97)
Query Neighborhood Hits	181	Target Neighborhood Hits	971	Shared Neighborhood Hits	27
SwissProt Accessions	P10070, O60252, O60253, O60254, O60255, Q15590, Q15591	Gene names	GLI2, THP
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI2 (Tax helper protein).

FOXP4_MOUSE
NC score	0.006348 (rank : 176)	θ value	8.99809 (rank : 168)
Query Neighborhood Hits	181	Target Neighborhood Hits	211	Shared Neighborhood Hits	11
SwissProt Accessions	Q9DBY0, Q80V92, Q8CG10, Q8CIS1	Gene names	Foxp4
Domain Architecture	No domain graphic available
Description	Forkhead box protein P4 (Fork head-related protein like A) (mFKHLA).

MK07_MOUSE
NC score	0.006222 (rank : 177)	θ value	4.03905 (rank : 102)
Query Neighborhood Hits	181	Target Neighborhood Hits	1054	Shared Neighborhood Hits	27
SwissProt Accessions	Q9WVS8	Gene names	Mapk7, Erk5
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (BMK1 kinase).

MARK2_HUMAN
NC score	0.006182 (rank : 178)	θ value	1.81305 (rank : 60)
Query Neighborhood Hits	181	Target Neighborhood Hits	1056	Shared Neighborhood Hits	26
SwissProt Accessions	Q7KZI7, Q15449, Q15524, Q5XGA3, Q68A18, Q96HB3, Q96RG0	Gene names	MARK2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (MAP/microtubule affinity-regulating kinase 2) (ELKL motif kinase) (EMK1) (PAR1 homolog).

GLI1_MOUSE
NC score	0.005442 (rank : 179)	θ value	3.0926 (rank : 85)
Query Neighborhood Hits	181	Target Neighborhood Hits	785	Shared Neighborhood Hits	17
SwissProt Accessions	P47806, Q9QYK1	Gene names	Gli1, Gli
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLI1 (Glioma-associated oncogene homolog).

CD2L2_HUMAN
NC score	0.005305 (rank : 180)	θ value	5.27518 (rank : 115)
Query Neighborhood Hits	181	Target Neighborhood Hits	1439	Shared Neighborhood Hits	33
SwissProt Accessions	Q9UQ88, O95227, O95228, O96012, Q12821, Q12853, Q12854, Q5QPR0, Q5QPR1, Q5QPR2, Q9UBC4, Q9UBI3, Q9UEI1, Q9UEI2, Q9UP53, Q9UP54, Q9UP55, Q9UP56, Q9UQ86, Q9UQ87, Q9UQ89	Gene names	CDC2L2, PITSLREB
Domain Architecture
Description	PITSLRE serine/threonine-protein kinase CDC2L2 (EC 2.7.11.22) (Galactosyltransferase-associated protein kinase p58/GTA) (Cell division cycle 2-like protein kinase 2) (CDK11).

MYLK_MOUSE
NC score	0.004654 (rank : 181)	θ value	8.99809 (rank : 172)
Query Neighborhood Hits	181	Target Neighborhood Hits	1489	Shared Neighborhood Hits	40
SwissProt Accessions	Q6PDN3, Q3TSJ7, Q80UX0, Q80YN7, Q80YN8, Q8K026, Q924D2, Q9ERD3	Gene names	Mylk
Domain Architecture	No domain graphic available
Description	Myosin light chain kinase, smooth muscle (EC 2.7.11.18) (MLCK) (Telokin) (Kinase-related protein) (KRP).

GLIS3_HUMAN
NC score	0.004508 (rank : 182)	θ value	4.03905 (rank : 98)
Query Neighborhood Hits	181	Target Neighborhood Hits	758	Shared Neighborhood Hits	17
SwissProt Accessions	Q8NEA6	Gene names	GLIS3, ZNF515
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLIS3 (GLI-similar 3) (Zinc finger protein 515).

THB1_MOUSE
NC score	0.003631 (rank : 183)	θ value	6.88961 (rank : 159)
Query Neighborhood Hits	181	Target Neighborhood Hits	105	Shared Neighborhood Hits	2
SwissProt Accessions	P37242	Gene names	Thrb, C-erba-beta, Nr1a2
Domain Architecture
Description	Thyroid hormone receptor beta-1.

PCDA6_HUMAN
NC score	0.002887 (rank : 184)	θ value	4.03905 (rank : 105)
Query Neighborhood Hits	181	Target Neighborhood Hits	187	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UN73, O75283, Q9NRT8	Gene names	PCDHA6
Domain Architecture
Description	Protocadherin alpha 6 precursor (PCDH-alpha6).

ZBT40_HUMAN
NC score	0.002845 (rank : 185)	θ value	4.03905 (rank : 108)
Query Neighborhood Hits	181	Target Neighborhood Hits	949	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NUA8, O75066, Q5TFU5, Q8N1R1	Gene names	ZBTB40, KIAA0478
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 40.

PLK4_MOUSE
NC score	0.001687 (rank : 186)	θ value	5.27518 (rank : 123)
Query Neighborhood Hits	181	Target Neighborhood Hits	879	Shared Neighborhood Hits	11
SwissProt Accessions	Q64702, Q6PEP6, Q78EG6, Q8R0I5, Q9CVR6, Q9CVU6	Gene names	Plk4, Sak, Stk18
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase PLK4 (EC 2.7.11.21) (Polo-like kinase 4) (PLK-4) (Serine/threonine-protein kinase Sak) (Serine/threonine- protein kinase 18).

ZN551_HUMAN
NC score	0.001394 (rank : 187)	θ value	1.81305 (rank : 64)
Query Neighborhood Hits	181	Target Neighborhood Hits	753	Shared Neighborhood Hits	10
SwissProt Accessions	Q7Z340, P17034, Q8N246, Q9BRY1	Gene names	ZNF551, KOX23
Domain Architecture	No domain graphic available
Description	Zinc finger protein 551 (Zinc finger protein KOX23).