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Network neighborhood for query Sequence : NTHL1_HUMAN

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NTHL1_HUMAN
SwissProt Accessions	P78549, Q99566, Q99794, Q9BPX2	Gene names	NTHL1, NTH1, OCTS3
Domain Architecture
Description	Endonuclease III-like protein 1 (EC 4.2.99.18).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

NTHL1_HUMAN
θ value	2.18449e-163 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	10
SwissProt Accessions	P78549, Q99566, Q99794, Q9BPX2	Gene names	NTHL1, NTH1, OCTS3
Domain Architecture
Description	Endonuclease III-like protein 1 (EC 4.2.99.18).

NTHL1_MOUSE
θ value	6.41512e-131 (rank : 2)	NC score	0.993801 (rank : 2)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	7
SwissProt Accessions	O35980	Gene names	Nthl1, Nth1
Domain Architecture
Description	Endonuclease III-like protein 1 (EC 4.2.99.18).

MUTYH_HUMAN
θ value	4.1701e-05 (rank : 3)	NC score	0.304968 (rank : 4)
Query Neighborhood Hits	10	Target Neighborhood Hits	20	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UIF7, Q15830, Q9UBP2, Q9UBS7, Q9UIF4, Q9UIF5, Q9UIF6	Gene names	MUTYH, MYH
Domain Architecture
Description	A/G-specific adenine DNA glycosylase (EC 3.2.2.-) (MutY homolog) (hMYH).

MUTYH_MOUSE
θ value	7.1131e-05 (rank : 4)	NC score	0.305006 (rank : 3)
Query Neighborhood Hits	10	Target Neighborhood Hits	18	Shared Neighborhood Hits	5
SwissProt Accessions	Q99P21	Gene names	Mutyh, Myh
Domain Architecture
Description	A/G-specific adenine DNA glycosylase (EC 3.2.2.-) (MutY homolog) (mMYH).

EHMT1_HUMAN
θ value	0.163984 (rank : 5)	NC score	0.022858 (rank : 8)
Query Neighborhood Hits	10	Target Neighborhood Hits	417	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H9B1, Q8TCN7, Q96F53, Q96JF1, Q96KH4	Gene names	EHMT1, EUHMTASE1, KIAA1876
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a- like protein 1) (GLP1).

OGG1_MOUSE
θ value	0.62314 (rank : 6)	NC score	0.092594 (rank : 6)
Query Neighborhood Hits	10	Target Neighborhood Hits	6	Shared Neighborhood Hits	4
SwissProt Accessions	O08760, O08733, O08910, O08991, O35617, O35915, Q9QXE8	Gene names	Ogg1
Domain Architecture
Description	N-glycosylase/DNA lyase [Includes: 8-oxoguanine DNA glycosylase (EC 3.2.2.-); DNA-(apurinic or apyrimidinic site) lyase (EC 4.2.99.18) (AP lyase)].

SDK2_HUMAN
θ value	1.38821 (rank : 7)	NC score	0.011272 (rank : 9)
Query Neighborhood Hits	10	Target Neighborhood Hits	495	Shared Neighborhood Hits	2
SwissProt Accessions	Q58EX2, Q86VY3, Q9NTD2, Q9NVB3, Q9P214	Gene names	SDK2, KIAA1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

DDX54_HUMAN
θ value	4.03905 (rank : 8)	NC score	0.009399 (rank : 10)
Query Neighborhood Hits	10	Target Neighborhood Hits	170	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TDD1, Q86YT8, Q9BRZ1	Gene names	DDX54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54) (ATP-dependent RNA helicase DP97).

OGG1_HUMAN
θ value	4.03905 (rank : 9)	NC score	0.103806 (rank : 5)
Query Neighborhood Hits	10	Target Neighborhood Hits	8	Shared Neighborhood Hits	5
SwissProt Accessions	O15527, O00390, O00670, O00705, O14876, O95488, P78554, Q9UIK0, Q9UIK1, Q9UIK2, Q9UL34, Q9Y2C0, Q9Y2C1, Q9Y6C3, Q9Y6C4	Gene names	OGG1, MMH, MUTM, OGH1
Domain Architecture
Description	N-glycosylase/DNA lyase [Includes: 8-oxoguanine DNA glycosylase (EC 3.2.2.-); DNA-(apurinic or apyrimidinic site) lyase (EC 4.2.99.18) (AP lyase)].

ALMS1_MOUSE
θ value	6.88961 (rank : 10)	NC score	0.031790 (rank : 7)
Query Neighborhood Hits	10	Target Neighborhood Hits	181	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K4E0, Q6A084, Q8C9N9	Gene names	Alms1, Kiaa0328
Domain Architecture	No domain graphic available
Description	Alstrom syndrome protein 1 homolog.

Hits sorted by NC score

NTHL1_HUMAN
NC score	0.999962 (rank : 1)	θ value	2.18449e-163 (rank : 1)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	10
SwissProt Accessions	P78549, Q99566, Q99794, Q9BPX2	Gene names	NTHL1, NTH1, OCTS3
Domain Architecture
Description	Endonuclease III-like protein 1 (EC 4.2.99.18).

NTHL1_MOUSE
NC score	0.993801 (rank : 2)	θ value	6.41512e-131 (rank : 2)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	7
SwissProt Accessions	O35980	Gene names	Nthl1, Nth1
Domain Architecture
Description	Endonuclease III-like protein 1 (EC 4.2.99.18).

MUTYH_MOUSE
NC score	0.305006 (rank : 3)	θ value	7.1131e-05 (rank : 4)
Query Neighborhood Hits	10	Target Neighborhood Hits	18	Shared Neighborhood Hits	5
SwissProt Accessions	Q99P21	Gene names	Mutyh, Myh
Domain Architecture
Description	A/G-specific adenine DNA glycosylase (EC 3.2.2.-) (MutY homolog) (mMYH).

MUTYH_HUMAN
NC score	0.304968 (rank : 4)	θ value	4.1701e-05 (rank : 3)
Query Neighborhood Hits	10	Target Neighborhood Hits	20	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UIF7, Q15830, Q9UBP2, Q9UBS7, Q9UIF4, Q9UIF5, Q9UIF6	Gene names	MUTYH, MYH
Domain Architecture
Description	A/G-specific adenine DNA glycosylase (EC 3.2.2.-) (MutY homolog) (hMYH).

OGG1_HUMAN
NC score	0.103806 (rank : 5)	θ value	4.03905 (rank : 9)
Query Neighborhood Hits	10	Target Neighborhood Hits	8	Shared Neighborhood Hits	5
SwissProt Accessions	O15527, O00390, O00670, O00705, O14876, O95488, P78554, Q9UIK0, Q9UIK1, Q9UIK2, Q9UL34, Q9Y2C0, Q9Y2C1, Q9Y6C3, Q9Y6C4	Gene names	OGG1, MMH, MUTM, OGH1
Domain Architecture
Description	N-glycosylase/DNA lyase [Includes: 8-oxoguanine DNA glycosylase (EC 3.2.2.-); DNA-(apurinic or apyrimidinic site) lyase (EC 4.2.99.18) (AP lyase)].

OGG1_MOUSE
NC score	0.092594 (rank : 6)	θ value	0.62314 (rank : 6)
Query Neighborhood Hits	10	Target Neighborhood Hits	6	Shared Neighborhood Hits	4
SwissProt Accessions	O08760, O08733, O08910, O08991, O35617, O35915, Q9QXE8	Gene names	Ogg1
Domain Architecture
Description	N-glycosylase/DNA lyase [Includes: 8-oxoguanine DNA glycosylase (EC 3.2.2.-); DNA-(apurinic or apyrimidinic site) lyase (EC 4.2.99.18) (AP lyase)].

ALMS1_MOUSE
NC score	0.031790 (rank : 7)	θ value	6.88961 (rank : 10)
Query Neighborhood Hits	10	Target Neighborhood Hits	181	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K4E0, Q6A084, Q8C9N9	Gene names	Alms1, Kiaa0328
Domain Architecture	No domain graphic available
Description	Alstrom syndrome protein 1 homolog.

EHMT1_HUMAN
NC score	0.022858 (rank : 8)	θ value	0.163984 (rank : 5)
Query Neighborhood Hits	10	Target Neighborhood Hits	417	Shared Neighborhood Hits	2
SwissProt Accessions	Q9H9B1, Q8TCN7, Q96F53, Q96JF1, Q96KH4	Gene names	EHMT1, EUHMTASE1, KIAA1876
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a- like protein 1) (GLP1).

SDK2_HUMAN
NC score	0.011272 (rank : 9)	θ value	1.38821 (rank : 7)
Query Neighborhood Hits	10	Target Neighborhood Hits	495	Shared Neighborhood Hits	2
SwissProt Accessions	Q58EX2, Q86VY3, Q9NTD2, Q9NVB3, Q9P214	Gene names	SDK2, KIAA1514
Domain Architecture	No domain graphic available
Description	Protein sidekick-2 precursor.

DDX54_HUMAN
NC score	0.009399 (rank : 10)	θ value	4.03905 (rank : 8)
Query Neighborhood Hits	10	Target Neighborhood Hits	170	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TDD1, Q86YT8, Q9BRZ1	Gene names	DDX54
Domain Architecture
Description	ATP-dependent RNA helicase DDX54 (EC 3.6.1.-) (DEAD box protein 54) (ATP-dependent RNA helicase DP97).