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Network neighborhood for query Sequence : MUTYH_MOUSE

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MUTYH_MOUSE
SwissProt Accessions	Q99P21	Gene names	Mutyh, Myh
Domain Architecture
Description	A/G-specific adenine DNA glycosylase (EC 3.2.2.-) (MutY homolog) (mMYH).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

MUTYH_HUMAN
θ value	0 (rank : 1)	NC score	0.989380 (rank : 2)
Query Neighborhood Hits	18	Target Neighborhood Hits	20	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UIF7, Q15830, Q9UBP2, Q9UBS7, Q9UIF4, Q9UIF5, Q9UIF6	Gene names	MUTYH, MYH
Domain Architecture
Description	A/G-specific adenine DNA glycosylase (EC 3.2.2.-) (MutY homolog) (hMYH).

MUTYH_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	18	Target Neighborhood Hits	18	Shared Neighborhood Hits	18
SwissProt Accessions	Q99P21	Gene names	Mutyh, Myh
Domain Architecture
Description	A/G-specific adenine DNA glycosylase (EC 3.2.2.-) (MutY homolog) (mMYH).

NTHL1_HUMAN
θ value	7.1131e-05 (rank : 3)	NC score	0.305006 (rank : 3)
Query Neighborhood Hits	18	Target Neighborhood Hits	10	Shared Neighborhood Hits	5
SwissProt Accessions	P78549, Q99566, Q99794, Q9BPX2	Gene names	NTHL1, NTH1, OCTS3
Domain Architecture
Description	Endonuclease III-like protein 1 (EC 4.2.99.18).

NTHL1_MOUSE
θ value	0.000461057 (rank : 4)	NC score	0.286165 (rank : 4)
Query Neighborhood Hits	18	Target Neighborhood Hits	10	Shared Neighborhood Hits	5
SwissProt Accessions	O35980	Gene names	Nthl1, Nth1
Domain Architecture
Description	Endonuclease III-like protein 1 (EC 4.2.99.18).

OGG1_HUMAN
θ value	0.163984 (rank : 5)	NC score	0.078807 (rank : 7)
Query Neighborhood Hits	18	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	O15527, O00390, O00670, O00705, O14876, O95488, P78554, Q9UIK0, Q9UIK1, Q9UIK2, Q9UL34, Q9Y2C0, Q9Y2C1, Q9Y6C3, Q9Y6C4	Gene names	OGG1, MMH, MUTM, OGH1
Domain Architecture
Description	N-glycosylase/DNA lyase [Includes: 8-oxoguanine DNA glycosylase (EC 3.2.2.-); DNA-(apurinic or apyrimidinic site) lyase (EC 4.2.99.18) (AP lyase)].

MBTP1_HUMAN
θ value	0.279714 (rank : 6)	NC score	0.097210 (rank : 6)
Query Neighborhood Hits	18	Target Neighborhood Hits	28	Shared Neighborhood Hits	4
SwissProt Accessions	Q14703, Q9UF67	Gene names	MBTPS1, KIAA0091, S1P, SKI1
Domain Architecture	No domain graphic available
Description	Membrane-bound transcription factor site 1 protease precursor (EC 3.4.21.-) (S1P endopeptidase) (Site-1 protease) (Subtilisin/kexin- isozyme 1) (SKI-1).

MBTP1_MOUSE
θ value	0.279714 (rank : 7)	NC score	0.097242 (rank : 5)
Query Neighborhood Hits	18	Target Neighborhood Hits	26	Shared Neighborhood Hits	4
SwissProt Accessions	Q9WTZ2, Q6PG67	Gene names	Mbtps1, S1p, Ski1
Domain Architecture
Description	Membrane-bound transcription factor site 1 protease precursor (EC 3.4.21.-) (S1P endopeptidase) (Site-1 protease) (Subtilisin/kexin isozyme 1) (SKI-1) (Sterol-regulated luminal protease).

CEP72_MOUSE
θ value	0.47712 (rank : 8)	NC score	0.039908 (rank : 11)
Query Neighborhood Hits	18	Target Neighborhood Hits	381	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D3R3, Q8BM53, Q9D0B7	Gene names	Cep72
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 72 kDa (Cep72 protein).

OSBL5_HUMAN
θ value	1.06291 (rank : 9)	NC score	0.026640 (rank : 13)
Query Neighborhood Hits	18	Target Neighborhood Hits	117	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H0X9, Q9BZB0, Q9P1Z4	Gene names	OSBPL5, KIAA1534, ORP5
Domain Architecture
Description	Oxysterol-binding protein-related protein 5 (OSBP-related protein 5) (ORP-5).

SRTD3_HUMAN
θ value	1.06291 (rank : 10)	NC score	0.066086 (rank : 8)
Query Neighborhood Hits	18	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UJW9, Q96CQ2	Gene names	SERTAD3, RBT1
Domain Architecture	No domain graphic available
Description	SERTA domain-containing protein 3 (Replication protein-binding trans- activator) (RPA-binding trans-activator).

PS1C2_HUMAN
θ value	3.0926 (rank : 11)	NC score	0.045860 (rank : 9)
Query Neighborhood Hits	18	Target Neighborhood Hits	66	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UIG4	Gene names	PSORS1C2, C6orf17, SPR1
Domain Architecture	No domain graphic available
Description	Psoriasis susceptibility 1 candidate gene 2 protein precursor (SPR1 protein).

PYGO2_HUMAN
θ value	3.0926 (rank : 12)	NC score	0.028566 (rank : 12)
Query Neighborhood Hits	18	Target Neighborhood Hits	189	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BRQ0, Q8WYZ4, Q96CY2	Gene names	PYGO2
Domain Architecture
Description	Pygopus homolog 2.

APOA4_HUMAN
θ value	4.03905 (rank : 13)	NC score	0.025900 (rank : 14)
Query Neighborhood Hits	18	Target Neighborhood Hits	399	Shared Neighborhood Hits	4
SwissProt Accessions	P06727, Q6Q787	Gene names	APOA4
Domain Architecture
Description	Apolipoprotein A-IV precursor (Apo-AIV) (ApoA-IV).

MYPN_MOUSE
θ value	4.03905 (rank : 14)	NC score	0.010820 (rank : 15)
Query Neighborhood Hits	18	Target Neighborhood Hits	421	Shared Neighborhood Hits	3
SwissProt Accessions	Q5DTJ9, Q7TPW5, Q8BZ76	Gene names	Mypn, Kiaa4170
Domain Architecture	No domain graphic available
Description	Myopalladin.

ABCC8_HUMAN
θ value	6.88961 (rank : 15)	NC score	0.006402 (rank : 17)
Query Neighborhood Hits	18	Target Neighborhood Hits	118	Shared Neighborhood Hits	2
SwissProt Accessions	Q09428, O75948, Q16583	Gene names	ABCC8, SUR, SUR1
Domain Architecture
Description	ATP-binding cassette transporter sub-family C member 8 (Sulfonylurea receptor 1).

SRTD3_MOUSE
θ value	6.88961 (rank : 16)	NC score	0.045492 (rank : 10)
Query Neighborhood Hits	18	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ERC3	Gene names	Sertad3, Rbt1
Domain Architecture	No domain graphic available
Description	SERTA domain-containing protein 3 (Replication protein-binding trans- activator) (RPA-binding trans-activator).

AFAD_HUMAN
θ value	8.99809 (rank : 17)	NC score	0.009273 (rank : 16)
Query Neighborhood Hits	18	Target Neighborhood Hits	689	Shared Neighborhood Hits	3
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

LAMA2_HUMAN
θ value	8.99809 (rank : 18)	NC score	0.003213 (rank : 18)
Query Neighborhood Hits	18	Target Neighborhood Hits	1092	Shared Neighborhood Hits	3
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

Hits sorted by NC score

MUTYH_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	18	Target Neighborhood Hits	18	Shared Neighborhood Hits	18
SwissProt Accessions	Q99P21	Gene names	Mutyh, Myh
Domain Architecture
Description	A/G-specific adenine DNA glycosylase (EC 3.2.2.-) (MutY homolog) (mMYH).

MUTYH_HUMAN
NC score	0.989380 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	18	Target Neighborhood Hits	20	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UIF7, Q15830, Q9UBP2, Q9UBS7, Q9UIF4, Q9UIF5, Q9UIF6	Gene names	MUTYH, MYH
Domain Architecture
Description	A/G-specific adenine DNA glycosylase (EC 3.2.2.-) (MutY homolog) (hMYH).

NTHL1_HUMAN
NC score	0.305006 (rank : 3)	θ value	7.1131e-05 (rank : 3)
Query Neighborhood Hits	18	Target Neighborhood Hits	10	Shared Neighborhood Hits	5
SwissProt Accessions	P78549, Q99566, Q99794, Q9BPX2	Gene names	NTHL1, NTH1, OCTS3
Domain Architecture
Description	Endonuclease III-like protein 1 (EC 4.2.99.18).

NTHL1_MOUSE
NC score	0.286165 (rank : 4)	θ value	0.000461057 (rank : 4)
Query Neighborhood Hits	18	Target Neighborhood Hits	10	Shared Neighborhood Hits	5
SwissProt Accessions	O35980	Gene names	Nthl1, Nth1
Domain Architecture
Description	Endonuclease III-like protein 1 (EC 4.2.99.18).

MBTP1_MOUSE
NC score	0.097242 (rank : 5)	θ value	0.279714 (rank : 7)
Query Neighborhood Hits	18	Target Neighborhood Hits	26	Shared Neighborhood Hits	4
SwissProt Accessions	Q9WTZ2, Q6PG67	Gene names	Mbtps1, S1p, Ski1
Domain Architecture
Description	Membrane-bound transcription factor site 1 protease precursor (EC 3.4.21.-) (S1P endopeptidase) (Site-1 protease) (Subtilisin/kexin isozyme 1) (SKI-1) (Sterol-regulated luminal protease).

MBTP1_HUMAN
NC score	0.097210 (rank : 6)	θ value	0.279714 (rank : 6)
Query Neighborhood Hits	18	Target Neighborhood Hits	28	Shared Neighborhood Hits	4
SwissProt Accessions	Q14703, Q9UF67	Gene names	MBTPS1, KIAA0091, S1P, SKI1
Domain Architecture	No domain graphic available
Description	Membrane-bound transcription factor site 1 protease precursor (EC 3.4.21.-) (S1P endopeptidase) (Site-1 protease) (Subtilisin/kexin- isozyme 1) (SKI-1).

OGG1_HUMAN
NC score	0.078807 (rank : 7)	θ value	0.163984 (rank : 5)
Query Neighborhood Hits	18	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	O15527, O00390, O00670, O00705, O14876, O95488, P78554, Q9UIK0, Q9UIK1, Q9UIK2, Q9UL34, Q9Y2C0, Q9Y2C1, Q9Y6C3, Q9Y6C4	Gene names	OGG1, MMH, MUTM, OGH1
Domain Architecture
Description	N-glycosylase/DNA lyase [Includes: 8-oxoguanine DNA glycosylase (EC 3.2.2.-); DNA-(apurinic or apyrimidinic site) lyase (EC 4.2.99.18) (AP lyase)].

SRTD3_HUMAN
NC score	0.066086 (rank : 8)	θ value	1.06291 (rank : 10)
Query Neighborhood Hits	18	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UJW9, Q96CQ2	Gene names	SERTAD3, RBT1
Domain Architecture	No domain graphic available
Description	SERTA domain-containing protein 3 (Replication protein-binding trans- activator) (RPA-binding trans-activator).

PS1C2_HUMAN
NC score	0.045860 (rank : 9)	θ value	3.0926 (rank : 11)
Query Neighborhood Hits	18	Target Neighborhood Hits	66	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UIG4	Gene names	PSORS1C2, C6orf17, SPR1
Domain Architecture	No domain graphic available
Description	Psoriasis susceptibility 1 candidate gene 2 protein precursor (SPR1 protein).

SRTD3_MOUSE
NC score	0.045492 (rank : 10)	θ value	6.88961 (rank : 16)
Query Neighborhood Hits	18	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ERC3	Gene names	Sertad3, Rbt1
Domain Architecture	No domain graphic available
Description	SERTA domain-containing protein 3 (Replication protein-binding trans- activator) (RPA-binding trans-activator).

CEP72_MOUSE
NC score	0.039908 (rank : 11)	θ value	0.47712 (rank : 8)
Query Neighborhood Hits	18	Target Neighborhood Hits	381	Shared Neighborhood Hits	2
SwissProt Accessions	Q9D3R3, Q8BM53, Q9D0B7	Gene names	Cep72
Domain Architecture	No domain graphic available
Description	Centrosomal protein of 72 kDa (Cep72 protein).

PYGO2_HUMAN
NC score	0.028566 (rank : 12)	θ value	3.0926 (rank : 12)
Query Neighborhood Hits	18	Target Neighborhood Hits	189	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BRQ0, Q8WYZ4, Q96CY2	Gene names	PYGO2
Domain Architecture
Description	Pygopus homolog 2.

OSBL5_HUMAN
NC score	0.026640 (rank : 13)	θ value	1.06291 (rank : 9)
Query Neighborhood Hits	18	Target Neighborhood Hits	117	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H0X9, Q9BZB0, Q9P1Z4	Gene names	OSBPL5, KIAA1534, ORP5
Domain Architecture
Description	Oxysterol-binding protein-related protein 5 (OSBP-related protein 5) (ORP-5).

APOA4_HUMAN
NC score	0.025900 (rank : 14)	θ value	4.03905 (rank : 13)
Query Neighborhood Hits	18	Target Neighborhood Hits	399	Shared Neighborhood Hits	4
SwissProt Accessions	P06727, Q6Q787	Gene names	APOA4
Domain Architecture
Description	Apolipoprotein A-IV precursor (Apo-AIV) (ApoA-IV).

MYPN_MOUSE
NC score	0.010820 (rank : 15)	θ value	4.03905 (rank : 14)
Query Neighborhood Hits	18	Target Neighborhood Hits	421	Shared Neighborhood Hits	3
SwissProt Accessions	Q5DTJ9, Q7TPW5, Q8BZ76	Gene names	Mypn, Kiaa4170
Domain Architecture	No domain graphic available
Description	Myopalladin.

AFAD_HUMAN
NC score	0.009273 (rank : 16)	θ value	8.99809 (rank : 17)
Query Neighborhood Hits	18	Target Neighborhood Hits	689	Shared Neighborhood Hits	3
SwissProt Accessions	P55196, O75087, O75088, O75089, Q5TIG6, Q9NSN7, Q9NU92	Gene names	MLLT4, AF6
Domain Architecture
Description	Afadin (Protein AF-6).

ABCC8_HUMAN
NC score	0.006402 (rank : 17)	θ value	6.88961 (rank : 15)
Query Neighborhood Hits	18	Target Neighborhood Hits	118	Shared Neighborhood Hits	2
SwissProt Accessions	Q09428, O75948, Q16583	Gene names	ABCC8, SUR, SUR1
Domain Architecture
Description	ATP-binding cassette transporter sub-family C member 8 (Sulfonylurea receptor 1).

LAMA2_HUMAN
NC score	0.003213 (rank : 18)	θ value	8.99809 (rank : 18)
Query Neighborhood Hits	18	Target Neighborhood Hits	1092	Shared Neighborhood Hits	3
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).