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Network neighborhood for query Sequence : SRTD3_MOUSE

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SRTD3_MOUSE
SwissProt Accessions	Q9ERC3	Gene names	Sertad3, Rbt1
Domain Architecture	No domain graphic available
Description	SERTA domain-containing protein 3 (Replication protein-binding trans- activator) (RPA-binding trans-activator).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SRTD3_MOUSE
θ value	2.73302e-81 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	13
SwissProt Accessions	Q9ERC3	Gene names	Sertad3, Rbt1
Domain Architecture	No domain graphic available
Description	SERTA domain-containing protein 3 (Replication protein-binding trans- activator) (RPA-binding trans-activator).

SRTD3_HUMAN
θ value	3.58603e-65 (rank : 2)	NC score	0.993803 (rank : 2)
Query Neighborhood Hits	13	Target Neighborhood Hits	12	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UJW9, Q96CQ2	Gene names	SERTAD3, RBT1
Domain Architecture	No domain graphic available
Description	SERTA domain-containing protein 3 (Replication protein-binding trans- activator) (RPA-binding trans-activator).

SRTD1_MOUSE
θ value	0.000121331 (rank : 3)	NC score	0.329297 (rank : 3)
Query Neighborhood Hits	13	Target Neighborhood Hits	20	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JL10, Q925E6, Q9D888	Gene names	Sertad1, Sei1
Domain Architecture
Description	SERTA domain-containing protein 1 (Transcriptional regulator interacting with the PHD-bromodomain 1) (TRIP-Br1) (CDK4-binding protein p34SEI1) (SEI-1).

CDCA4_MOUSE
θ value	0.00509761 (rank : 4)	NC score	0.257679 (rank : 4)
Query Neighborhood Hits	13	Target Neighborhood Hits	14	Shared Neighborhood Hits	6
SwissProt Accessions	Q9CWM2, Q3U1C0, Q921E8, Q99MP6	Gene names	Cdca4, Hepp
Domain Architecture
Description	Cell division cycle-associated protein 4 (Hematopoietic progenitor protein).

M3K4_MOUSE
θ value	0.0252991 (rank : 5)	NC score	0.028763 (rank : 13)
Query Neighborhood Hits	13	Target Neighborhood Hits	924	Shared Neighborhood Hits	4
SwissProt Accessions	O08648, O08649, O70124	Gene names	Map3k4, Mekk4
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4).

CDCA4_HUMAN
θ value	1.06291 (rank : 6)	NC score	0.173097 (rank : 5)
Query Neighborhood Hits	13	Target Neighborhood Hits	12	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BXL8, Q8TB18, Q9NWK7	Gene names	CDCA4, HEPP
Domain Architecture
Description	Cell division cycle-associated protein 4 (Hematopoietic progenitor protein).

M3K4_HUMAN
θ value	1.06291 (rank : 7)	NC score	0.021497 (rank : 14)
Query Neighborhood Hits	13	Target Neighborhood Hits	911	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y6R4, Q92612	Gene names	MAP3K4, KIAA0213, MAPKKK4, MEKK4, MTK1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4) (MAP three kinase 1).

ICB1_HUMAN
θ value	3.0926 (rank : 8)	NC score	0.051335 (rank : 9)
Query Neighborhood Hits	13	Target Neighborhood Hits	20	Shared Neighborhood Hits	3
SwissProt Accessions	Q5TEJ8, O60560, Q5TEJ1, Q5TEJ9, Q5TEK1, Q68DP4, Q9BYB6, Q9NS90	Gene names	ICB1, C1orf38
Domain Architecture	No domain graphic available
Description	Induced by contact to basement membrane 1 protein (Protein ICB-1).

CBL_HUMAN
θ value	4.03905 (rank : 9)	NC score	0.019666 (rank : 15)
Query Neighborhood Hits	13	Target Neighborhood Hits	353	Shared Neighborhood Hits	2
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).

MUTYH_MOUSE
θ value	6.88961 (rank : 10)	NC score	0.045492 (rank : 10)
Query Neighborhood Hits	13	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	Q99P21	Gene names	Mutyh, Myh
Domain Architecture
Description	A/G-specific adenine DNA glycosylase (EC 3.2.2.-) (MutY homolog) (mMYH).

RUVB1_HUMAN
θ value	6.88961 (rank : 11)	NC score	0.029713 (rank : 11)
Query Neighborhood Hits	13	Target Neighborhood Hits	78	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y265, Q9BSX9	Gene names	RUVBL1, NMP238, TIP49, TIP49A
Domain Architecture
Description	RuvB-like 1 (EC 3.6.1.-) (49 kDa TATA box-binding protein-interacting protein) (49 kDa TBP-interacting protein) (TIP49a) (Pontin 52) (Nuclear matrix protein 238) (NMP 238) (54 kDa erythrocyte cytosolic protein) (ECP-54) (TIP60-associated protein 54-alpha) (TAP54-alpha).

RUVB1_MOUSE
θ value	6.88961 (rank : 12)	NC score	0.029710 (rank : 12)
Query Neighborhood Hits	13	Target Neighborhood Hits	78	Shared Neighborhood Hits	3
SwissProt Accessions	P60122, O35753	Gene names	Ruvbl1, Tip49, Tip49a
Domain Architecture
Description	RuvB-like 1 (EC 3.6.1.-) (49 kDa TATA box-binding protein-interacting protein) (49 kDa TBP-interacting protein) (TIP49a) (Pontin 52) (DNA helicase p50).

SRTD1_HUMAN
θ value	8.99809 (rank : 13)	NC score	0.163663 (rank : 6)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UHV2, Q9BUE7	Gene names	SERTAD1, SEI1
Domain Architecture
Description	SERTA domain-containing protein 1 (Transcriptional regulator interacting with the PHD-bromodomain 1) (TRIP-Br1) (CDK4-binding protein p34SEI1) (SEI-1).

SRTD2_HUMAN
θ value	θ > 10 (rank : 14)	NC score	0.060677 (rank : 8)
Query Neighborhood Hits	13	Target Neighborhood Hits	62	Shared Neighborhood Hits	5
SwissProt Accessions	Q14140	Gene names	SERTAD2, KIAA0127
Domain Architecture	No domain graphic available
Description	SERTA domain-containing protein 2 (Transcriptional regulator interacting with the PHD-bromodomain 2) (TRIP-Br2).

SRTD2_MOUSE
θ value	θ > 10 (rank : 15)	NC score	0.073562 (rank : 7)
Query Neighborhood Hits	13	Target Neighborhood Hits	21	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JJG5, Q8C609, Q91WL3, Q925E5	Gene names	Sertad2, Kiaa0127
Domain Architecture
Description	SERTA domain-containing protein 2 (Transcriptional regulator interacting with the PHD-bromodomain 2) (TRIP-Br2).

Hits sorted by NC score

SRTD3_MOUSE
NC score	0.999962 (rank : 1)	θ value	2.73302e-81 (rank : 1)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	13
SwissProt Accessions	Q9ERC3	Gene names	Sertad3, Rbt1
Domain Architecture	No domain graphic available
Description	SERTA domain-containing protein 3 (Replication protein-binding trans- activator) (RPA-binding trans-activator).

SRTD3_HUMAN
NC score	0.993803 (rank : 2)	θ value	3.58603e-65 (rank : 2)
Query Neighborhood Hits	13	Target Neighborhood Hits	12	Shared Neighborhood Hits	9
SwissProt Accessions	Q9UJW9, Q96CQ2	Gene names	SERTAD3, RBT1
Domain Architecture	No domain graphic available
Description	SERTA domain-containing protein 3 (Replication protein-binding trans- activator) (RPA-binding trans-activator).

SRTD1_MOUSE
NC score	0.329297 (rank : 3)	θ value	0.000121331 (rank : 3)
Query Neighborhood Hits	13	Target Neighborhood Hits	20	Shared Neighborhood Hits	6
SwissProt Accessions	Q9JL10, Q925E6, Q9D888	Gene names	Sertad1, Sei1
Domain Architecture
Description	SERTA domain-containing protein 1 (Transcriptional regulator interacting with the PHD-bromodomain 1) (TRIP-Br1) (CDK4-binding protein p34SEI1) (SEI-1).

CDCA4_MOUSE
NC score	0.257679 (rank : 4)	θ value	0.00509761 (rank : 4)
Query Neighborhood Hits	13	Target Neighborhood Hits	14	Shared Neighborhood Hits	6
SwissProt Accessions	Q9CWM2, Q3U1C0, Q921E8, Q99MP6	Gene names	Cdca4, Hepp
Domain Architecture
Description	Cell division cycle-associated protein 4 (Hematopoietic progenitor protein).

CDCA4_HUMAN
NC score	0.173097 (rank : 5)	θ value	1.06291 (rank : 6)
Query Neighborhood Hits	13	Target Neighborhood Hits	12	Shared Neighborhood Hits	6
SwissProt Accessions	Q9BXL8, Q8TB18, Q9NWK7	Gene names	CDCA4, HEPP
Domain Architecture
Description	Cell division cycle-associated protein 4 (Hematopoietic progenitor protein).

SRTD1_HUMAN
NC score	0.163663 (rank : 6)	θ value	8.99809 (rank : 13)
Query Neighborhood Hits	13	Target Neighborhood Hits	13	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UHV2, Q9BUE7	Gene names	SERTAD1, SEI1
Domain Architecture
Description	SERTA domain-containing protein 1 (Transcriptional regulator interacting with the PHD-bromodomain 1) (TRIP-Br1) (CDK4-binding protein p34SEI1) (SEI-1).

SRTD2_MOUSE
NC score	0.073562 (rank : 7)	θ value	θ > 10 (rank : 15)
Query Neighborhood Hits	13	Target Neighborhood Hits	21	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JJG5, Q8C609, Q91WL3, Q925E5	Gene names	Sertad2, Kiaa0127
Domain Architecture
Description	SERTA domain-containing protein 2 (Transcriptional regulator interacting with the PHD-bromodomain 2) (TRIP-Br2).

SRTD2_HUMAN
NC score	0.060677 (rank : 8)	θ value	θ > 10 (rank : 14)
Query Neighborhood Hits	13	Target Neighborhood Hits	62	Shared Neighborhood Hits	5
SwissProt Accessions	Q14140	Gene names	SERTAD2, KIAA0127
Domain Architecture	No domain graphic available
Description	SERTA domain-containing protein 2 (Transcriptional regulator interacting with the PHD-bromodomain 2) (TRIP-Br2).

ICB1_HUMAN
NC score	0.051335 (rank : 9)	θ value	3.0926 (rank : 8)
Query Neighborhood Hits	13	Target Neighborhood Hits	20	Shared Neighborhood Hits	3
SwissProt Accessions	Q5TEJ8, O60560, Q5TEJ1, Q5TEJ9, Q5TEK1, Q68DP4, Q9BYB6, Q9NS90	Gene names	ICB1, C1orf38
Domain Architecture	No domain graphic available
Description	Induced by contact to basement membrane 1 protein (Protein ICB-1).

MUTYH_MOUSE
NC score	0.045492 (rank : 10)	θ value	6.88961 (rank : 10)
Query Neighborhood Hits	13	Target Neighborhood Hits	18	Shared Neighborhood Hits	3
SwissProt Accessions	Q99P21	Gene names	Mutyh, Myh
Domain Architecture
Description	A/G-specific adenine DNA glycosylase (EC 3.2.2.-) (MutY homolog) (mMYH).

RUVB1_HUMAN
NC score	0.029713 (rank : 11)	θ value	6.88961 (rank : 11)
Query Neighborhood Hits	13	Target Neighborhood Hits	78	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y265, Q9BSX9	Gene names	RUVBL1, NMP238, TIP49, TIP49A
Domain Architecture
Description	RuvB-like 1 (EC 3.6.1.-) (49 kDa TATA box-binding protein-interacting protein) (49 kDa TBP-interacting protein) (TIP49a) (Pontin 52) (Nuclear matrix protein 238) (NMP 238) (54 kDa erythrocyte cytosolic protein) (ECP-54) (TIP60-associated protein 54-alpha) (TAP54-alpha).

RUVB1_MOUSE
NC score	0.029710 (rank : 12)	θ value	6.88961 (rank : 12)
Query Neighborhood Hits	13	Target Neighborhood Hits	78	Shared Neighborhood Hits	3
SwissProt Accessions	P60122, O35753	Gene names	Ruvbl1, Tip49, Tip49a
Domain Architecture
Description	RuvB-like 1 (EC 3.6.1.-) (49 kDa TATA box-binding protein-interacting protein) (49 kDa TBP-interacting protein) (TIP49a) (Pontin 52) (DNA helicase p50).

M3K4_MOUSE
NC score	0.028763 (rank : 13)	θ value	0.0252991 (rank : 5)
Query Neighborhood Hits	13	Target Neighborhood Hits	924	Shared Neighborhood Hits	4
SwissProt Accessions	O08648, O08649, O70124	Gene names	Map3k4, Mekk4
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4).

M3K4_HUMAN
NC score	0.021497 (rank : 14)	θ value	1.06291 (rank : 7)
Query Neighborhood Hits	13	Target Neighborhood Hits	911	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Y6R4, Q92612	Gene names	MAP3K4, KIAA0213, MAPKKK4, MEKK4, MTK1
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4) (MAP three kinase 1).

CBL_HUMAN
NC score	0.019666 (rank : 15)	θ value	4.03905 (rank : 9)
Query Neighborhood Hits	13	Target Neighborhood Hits	353	Shared Neighborhood Hits	2
SwissProt Accessions	P22681	Gene names	CBL, CBL2, RNF55
Domain Architecture
Description	E3 ubiquitin-protein ligase CBL (EC 6.3.2.-) (Signal transduction protein CBL) (Proto-oncogene c-CBL) (Casitas B-lineage lymphoma proto- oncogene) (RING finger protein 55).