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Network neighborhood for query Sequence : ICB1_HUMAN

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ICB1_HUMAN
SwissProt Accessions	Q5TEJ8, O60560, Q5TEJ1, Q5TEJ9, Q5TEK1, Q68DP4, Q9BYB6, Q9NS90	Gene names	ICB1, C1orf38
Domain Architecture	No domain graphic available
Description	Induced by contact to basement membrane 1 protein (Protein ICB-1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

ICB1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	20	Target Neighborhood Hits	20	Shared Neighborhood Hits	20
SwissProt Accessions	Q5TEJ8, O60560, Q5TEJ1, Q5TEJ9, Q5TEK1, Q68DP4, Q9BYB6, Q9NS90	Gene names	ICB1, C1orf38
Domain Architecture	No domain graphic available
Description	Induced by contact to basement membrane 1 protein (Protein ICB-1).

ICB1_MOUSE
θ value	0 (rank : 2)	NC score	0.979656 (rank : 2)
Query Neighborhood Hits	20	Target Neighborhood Hits	69	Shared Neighborhood Hits	4
SwissProt Accessions	Q91YX0	Gene names	Icb1
Domain Architecture	No domain graphic available
Description	Induced by contact to basement membrane 1 protein homolog (ICB-1 protein).

CF190_HUMAN
θ value	5.51964e-74 (rank : 3)	NC score	0.893779 (rank : 3)
Query Neighborhood Hits	20	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N1K5, Q5T3C4, Q5T3C5, Q6MZT7	Gene names	C6orf190
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf190.

CF190_MOUSE
θ value	4.52582e-68 (rank : 4)	NC score	0.889615 (rank : 4)
Query Neighborhood Hits	20	Target Neighborhood Hits	11	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BGW0, Q3TEM0, Q3UU76, Q8BGP0, Q8C9S6	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf190 homolog.

SRTD3_HUMAN
θ value	0.813845 (rank : 5)	NC score	0.064199 (rank : 5)
Query Neighborhood Hits	20	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UJW9, Q96CQ2	Gene names	SERTAD3, RBT1
Domain Architecture	No domain graphic available
Description	SERTA domain-containing protein 3 (Replication protein-binding trans- activator) (RPA-binding trans-activator).

TREF1_HUMAN
θ value	1.38821 (rank : 6)	NC score	0.020733 (rank : 9)
Query Neighborhood Hits	20	Target Neighborhood Hits	651	Shared Neighborhood Hits	4
SwissProt Accessions	Q96PN7, Q7Z6T2, Q7Z6T3, Q9NQ72, Q9NQ73, Q9NUN9	Gene names	TRERF1, RAPA, TREP132
Domain Architecture	No domain graphic available
Description	Transcriptional-regulating factor 1 (Transcriptional-regulating protein 132) (Zinc finger transcription factor TReP-132) (Zinc finger protein rapa).

CAD17_HUMAN
θ value	3.0926 (rank : 7)	NC score	0.008824 (rank : 17)
Query Neighborhood Hits	20	Target Neighborhood Hits	154	Shared Neighborhood Hits	3
SwissProt Accessions	Q12864, Q15336	Gene names	CDH17
Domain Architecture
Description	Cadherin-17 precursor (Liver-intestine-cadherin) (LI-cadherin) (Intestinal peptide-associated transporter HPT-1).

SRTD3_MOUSE
θ value	3.0926 (rank : 8)	NC score	0.051335 (rank : 6)
Query Neighborhood Hits	20	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ERC3	Gene names	Sertad3, Rbt1
Domain Architecture	No domain graphic available
Description	SERTA domain-containing protein 3 (Replication protein-binding trans- activator) (RPA-binding trans-activator).

P66B_HUMAN
θ value	4.03905 (rank : 9)	NC score	0.027374 (rank : 7)
Query Neighborhood Hits	20	Target Neighborhood Hits	61	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WXI9, Q7LG68, Q9ULS0	Gene names	GATAD2B, KIAA1150
Domain Architecture	No domain graphic available
Description	Transcriptional repressor p66 beta (p66/p68) (GATA zinc finger domain- containing protein 2B).

CAD17_MOUSE
θ value	5.27518 (rank : 10)	NC score	0.007864 (rank : 18)
Query Neighborhood Hits	20	Target Neighborhood Hits	157	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R100	Gene names	Cdh17
Domain Architecture
Description	Cadherin-17 precursor (Liver-intestine-cadherin) (LI-cadherin) (BILL- cadherin) (P130).

P66B_MOUSE
θ value	5.27518 (rank : 11)	NC score	0.026046 (rank : 8)
Query Neighborhood Hits	20	Target Neighborhood Hits	64	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VHR5, Q8C9Q3	Gene names	Gatad2b
Domain Architecture	No domain graphic available
Description	Transcriptional repressor p66 beta (p66/p68) (GATA zinc finger domain- containing protein 2B).

PRDM1_MOUSE
θ value	5.27518 (rank : 12)	NC score	0.001563 (rank : 19)
Query Neighborhood Hits	20	Target Neighborhood Hits	766	Shared Neighborhood Hits	4
SwissProt Accessions	Q60636	Gene names	Prdm1, Blimp1
Domain Architecture
Description	PR domain zinc finger protein 1 (PR domain-containing protein 1) (Beta-interferon gene positive-regulatory domain I-binding factor) (BLIMP-1).

ZN227_HUMAN
θ value	5.27518 (rank : 13)	NC score	0.000390 (rank : 20)
Query Neighborhood Hits	20	Target Neighborhood Hits	781	Shared Neighborhood Hits	4
SwissProt Accessions	Q86WZ6	Gene names	ZNF227
Domain Architecture	No domain graphic available
Description	Zinc finger protein 227.

BRD2_HUMAN
θ value	6.88961 (rank : 14)	NC score	0.010948 (rank : 15)
Query Neighborhood Hits	20	Target Neighborhood Hits	242	Shared Neighborhood Hits	3
SwissProt Accessions	P25440, O00699, O00700, Q15310, Q5STC9, Q969U4	Gene names	BRD2, KIAA9001, RING3
Domain Architecture
Description	Bromodomain-containing protein 2 (Protein RING3) (O27.1.1).

PRGC2_HUMAN
θ value	6.88961 (rank : 15)	NC score	0.013333 (rank : 10)
Query Neighborhood Hits	20	Target Neighborhood Hits	272	Shared Neighborhood Hits	2
SwissProt Accessions	Q86YN6, Q86YN3, Q86YN4, Q86YN5, Q8N1N9, Q8TDE4, Q8TDE5	Gene names	PPARGC1B, PERC, PGC1, PGC1B, PPARGC1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta) (PGC-1-related estrogen receptor alpha coactivator) (PPARGC-1-beta) (PGC-1-beta).

SPI1_MOUSE
θ value	6.88961 (rank : 16)	NC score	0.011663 (rank : 13)
Query Neighborhood Hits	20	Target Neighborhood Hits	47	Shared Neighborhood Hits	2
SwissProt Accessions	P17433, Q99L57	Gene names	Spi1, Sfpi-1, Sfpi1
Domain Architecture
Description	Transcription factor PU.1 (31 kDa transforming protein) (SFFV proviral integration 1 protein).

BRD3_HUMAN
θ value	8.99809 (rank : 17)	NC score	0.009249 (rank : 16)
Query Neighborhood Hits	20	Target Neighborhood Hits	369	Shared Neighborhood Hits	3
SwissProt Accessions	Q15059, Q5T1R7, Q8N5M3, Q92645	Gene names	BRD3, KIAA0043, RING3L
Domain Architecture
Description	Bromodomain-containing protein 3 (RING3-like protein).

ODP2_HUMAN
θ value	8.99809 (rank : 18)	NC score	0.011659 (rank : 14)
Query Neighborhood Hits	20	Target Neighborhood Hits	59	Shared Neighborhood Hits	2
SwissProt Accessions	P10515, Q16783	Gene names	DLAT, DLTA
Domain Architecture
Description	Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial precursor (EC 2.3.1.12) (Pyruvate dehydrogenase complex E2 subunit) (PDCE2) (E2) (Dihydrolipoamide S- acetyltransferase component of pyruvate dehydrogenase complex) (PDC- E2) (70 kDa mitochondrial autoantigen of primary biliary cirrhosis) (PBC) (M2 antigen complex 70 kDa subunit).

RNF25_HUMAN
θ value	8.99809 (rank : 19)	NC score	0.012459 (rank : 12)
Query Neighborhood Hits	20	Target Neighborhood Hits	163	Shared Neighborhood Hits	2
SwissProt Accessions	Q96BH1, Q9H874	Gene names	RNF25
Domain Architecture
Description	RING finger protein 25 (EC 6.3.2.-).

VEGFB_MOUSE
θ value	8.99809 (rank : 20)	NC score	0.012516 (rank : 11)
Query Neighborhood Hits	20	Target Neighborhood Hits	33	Shared Neighborhood Hits	2
SwissProt Accessions	P49766, Q3UG04, Q5D0B1, Q64290	Gene names	Vegfb, Vrf
Domain Architecture
Description	Vascular endothelial growth factor B precursor (VEGF-B) (VEGF-related factor) (VRF).

Hits sorted by NC score

ICB1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	20	Target Neighborhood Hits	20	Shared Neighborhood Hits	20
SwissProt Accessions	Q5TEJ8, O60560, Q5TEJ1, Q5TEJ9, Q5TEK1, Q68DP4, Q9BYB6, Q9NS90	Gene names	ICB1, C1orf38
Domain Architecture	No domain graphic available
Description	Induced by contact to basement membrane 1 protein (Protein ICB-1).

ICB1_MOUSE
NC score	0.979656 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	20	Target Neighborhood Hits	69	Shared Neighborhood Hits	4
SwissProt Accessions	Q91YX0	Gene names	Icb1
Domain Architecture	No domain graphic available
Description	Induced by contact to basement membrane 1 protein homolog (ICB-1 protein).

CF190_HUMAN
NC score	0.893779 (rank : 3)	θ value	5.51964e-74 (rank : 3)
Query Neighborhood Hits	20	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	Q8N1K5, Q5T3C4, Q5T3C5, Q6MZT7	Gene names	C6orf190
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf190.

CF190_MOUSE
NC score	0.889615 (rank : 4)	θ value	4.52582e-68 (rank : 4)
Query Neighborhood Hits	20	Target Neighborhood Hits	11	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BGW0, Q3TEM0, Q3UU76, Q8BGP0, Q8C9S6	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C6orf190 homolog.

SRTD3_HUMAN
NC score	0.064199 (rank : 5)	θ value	0.813845 (rank : 5)
Query Neighborhood Hits	20	Target Neighborhood Hits	12	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UJW9, Q96CQ2	Gene names	SERTAD3, RBT1
Domain Architecture	No domain graphic available
Description	SERTA domain-containing protein 3 (Replication protein-binding trans- activator) (RPA-binding trans-activator).

SRTD3_MOUSE
NC score	0.051335 (rank : 6)	θ value	3.0926 (rank : 8)
Query Neighborhood Hits	20	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ERC3	Gene names	Sertad3, Rbt1
Domain Architecture	No domain graphic available
Description	SERTA domain-containing protein 3 (Replication protein-binding trans- activator) (RPA-binding trans-activator).

P66B_HUMAN
NC score	0.027374 (rank : 7)	θ value	4.03905 (rank : 9)
Query Neighborhood Hits	20	Target Neighborhood Hits	61	Shared Neighborhood Hits	3
SwissProt Accessions	Q8WXI9, Q7LG68, Q9ULS0	Gene names	GATAD2B, KIAA1150
Domain Architecture	No domain graphic available
Description	Transcriptional repressor p66 beta (p66/p68) (GATA zinc finger domain- containing protein 2B).

P66B_MOUSE
NC score	0.026046 (rank : 8)	θ value	5.27518 (rank : 11)
Query Neighborhood Hits	20	Target Neighborhood Hits	64	Shared Neighborhood Hits	3
SwissProt Accessions	Q8VHR5, Q8C9Q3	Gene names	Gatad2b
Domain Architecture	No domain graphic available
Description	Transcriptional repressor p66 beta (p66/p68) (GATA zinc finger domain- containing protein 2B).

TREF1_HUMAN
NC score	0.020733 (rank : 9)	θ value	1.38821 (rank : 6)
Query Neighborhood Hits	20	Target Neighborhood Hits	651	Shared Neighborhood Hits	4
SwissProt Accessions	Q96PN7, Q7Z6T2, Q7Z6T3, Q9NQ72, Q9NQ73, Q9NUN9	Gene names	TRERF1, RAPA, TREP132
Domain Architecture	No domain graphic available
Description	Transcriptional-regulating factor 1 (Transcriptional-regulating protein 132) (Zinc finger transcription factor TReP-132) (Zinc finger protein rapa).

PRGC2_HUMAN
NC score	0.013333 (rank : 10)	θ value	6.88961 (rank : 15)
Query Neighborhood Hits	20	Target Neighborhood Hits	272	Shared Neighborhood Hits	2
SwissProt Accessions	Q86YN6, Q86YN3, Q86YN4, Q86YN5, Q8N1N9, Q8TDE4, Q8TDE5	Gene names	PPARGC1B, PERC, PGC1, PGC1B, PPARGC1
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor gamma coactivator 1-beta (PPAR gamma coactivator-1beta) (PGC-1-related estrogen receptor alpha coactivator) (PPARGC-1-beta) (PGC-1-beta).

VEGFB_MOUSE
NC score	0.012516 (rank : 11)	θ value	8.99809 (rank : 20)
Query Neighborhood Hits	20	Target Neighborhood Hits	33	Shared Neighborhood Hits	2
SwissProt Accessions	P49766, Q3UG04, Q5D0B1, Q64290	Gene names	Vegfb, Vrf
Domain Architecture
Description	Vascular endothelial growth factor B precursor (VEGF-B) (VEGF-related factor) (VRF).

RNF25_HUMAN
NC score	0.012459 (rank : 12)	θ value	8.99809 (rank : 19)
Query Neighborhood Hits	20	Target Neighborhood Hits	163	Shared Neighborhood Hits	2
SwissProt Accessions	Q96BH1, Q9H874	Gene names	RNF25
Domain Architecture
Description	RING finger protein 25 (EC 6.3.2.-).

SPI1_MOUSE
NC score	0.011663 (rank : 13)	θ value	6.88961 (rank : 16)
Query Neighborhood Hits	20	Target Neighborhood Hits	47	Shared Neighborhood Hits	2
SwissProt Accessions	P17433, Q99L57	Gene names	Spi1, Sfpi-1, Sfpi1
Domain Architecture
Description	Transcription factor PU.1 (31 kDa transforming protein) (SFFV proviral integration 1 protein).

ODP2_HUMAN
NC score	0.011659 (rank : 14)	θ value	8.99809 (rank : 18)
Query Neighborhood Hits	20	Target Neighborhood Hits	59	Shared Neighborhood Hits	2
SwissProt Accessions	P10515, Q16783	Gene names	DLAT, DLTA
Domain Architecture
Description	Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial precursor (EC 2.3.1.12) (Pyruvate dehydrogenase complex E2 subunit) (PDCE2) (E2) (Dihydrolipoamide S- acetyltransferase component of pyruvate dehydrogenase complex) (PDC- E2) (70 kDa mitochondrial autoantigen of primary biliary cirrhosis) (PBC) (M2 antigen complex 70 kDa subunit).

BRD2_HUMAN
NC score	0.010948 (rank : 15)	θ value	6.88961 (rank : 14)
Query Neighborhood Hits	20	Target Neighborhood Hits	242	Shared Neighborhood Hits	3
SwissProt Accessions	P25440, O00699, O00700, Q15310, Q5STC9, Q969U4	Gene names	BRD2, KIAA9001, RING3
Domain Architecture
Description	Bromodomain-containing protein 2 (Protein RING3) (O27.1.1).

BRD3_HUMAN
NC score	0.009249 (rank : 16)	θ value	8.99809 (rank : 17)
Query Neighborhood Hits	20	Target Neighborhood Hits	369	Shared Neighborhood Hits	3
SwissProt Accessions	Q15059, Q5T1R7, Q8N5M3, Q92645	Gene names	BRD3, KIAA0043, RING3L
Domain Architecture
Description	Bromodomain-containing protein 3 (RING3-like protein).

CAD17_HUMAN
NC score	0.008824 (rank : 17)	θ value	3.0926 (rank : 7)
Query Neighborhood Hits	20	Target Neighborhood Hits	154	Shared Neighborhood Hits	3
SwissProt Accessions	Q12864, Q15336	Gene names	CDH17
Domain Architecture
Description	Cadherin-17 precursor (Liver-intestine-cadherin) (LI-cadherin) (Intestinal peptide-associated transporter HPT-1).

CAD17_MOUSE
NC score	0.007864 (rank : 18)	θ value	5.27518 (rank : 10)
Query Neighborhood Hits	20	Target Neighborhood Hits	157	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R100	Gene names	Cdh17
Domain Architecture
Description	Cadherin-17 precursor (Liver-intestine-cadherin) (LI-cadherin) (BILL- cadherin) (P130).

PRDM1_MOUSE
NC score	0.001563 (rank : 19)	θ value	5.27518 (rank : 12)
Query Neighborhood Hits	20	Target Neighborhood Hits	766	Shared Neighborhood Hits	4
SwissProt Accessions	Q60636	Gene names	Prdm1, Blimp1
Domain Architecture
Description	PR domain zinc finger protein 1 (PR domain-containing protein 1) (Beta-interferon gene positive-regulatory domain I-binding factor) (BLIMP-1).

ZN227_HUMAN
NC score	0.000390 (rank : 20)	θ value	5.27518 (rank : 13)
Query Neighborhood Hits	20	Target Neighborhood Hits	781	Shared Neighborhood Hits	4
SwissProt Accessions	Q86WZ6	Gene names	ZNF227
Domain Architecture	No domain graphic available
Description	Zinc finger protein 227.