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Network neighborhood for query Sequence : SRTD1_MOUSE

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SRTD1_MOUSE
SwissProt Accessions	Q9JL10, Q925E6, Q9D888	Gene names	Sertad1, Sei1
Domain Architecture
Description	SERTA domain-containing protein 1 (Transcriptional regulator interacting with the PHD-bromodomain 1) (TRIP-Br1) (CDK4-binding protein p34SEI1) (SEI-1).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SRTD1_MOUSE
θ value	3.80478e-91 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	20	Target Neighborhood Hits	20	Shared Neighborhood Hits	20
SwissProt Accessions	Q9JL10, Q925E6, Q9D888	Gene names	Sertad1, Sei1
Domain Architecture
Description	SERTA domain-containing protein 1 (Transcriptional regulator interacting with the PHD-bromodomain 1) (TRIP-Br1) (CDK4-binding protein p34SEI1) (SEI-1).

SRTD1_HUMAN
θ value	4.22625e-74 (rank : 2)	NC score	0.975951 (rank : 2)
Query Neighborhood Hits	20	Target Neighborhood Hits	13	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UHV2, Q9BUE7	Gene names	SERTAD1, SEI1
Domain Architecture
Description	SERTA domain-containing protein 1 (Transcriptional regulator interacting with the PHD-bromodomain 1) (TRIP-Br1) (CDK4-binding protein p34SEI1) (SEI-1).

CDCA4_MOUSE
θ value	8.97725e-08 (rank : 3)	NC score	0.505248 (rank : 3)
Query Neighborhood Hits	20	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	Q9CWM2, Q3U1C0, Q921E8, Q99MP6	Gene names	Cdca4, Hepp
Domain Architecture
Description	Cell division cycle-associated protein 4 (Hematopoietic progenitor protein).

SRTD2_HUMAN
θ value	1.69304e-06 (rank : 4)	NC score	0.440015 (rank : 6)
Query Neighborhood Hits	20	Target Neighborhood Hits	62	Shared Neighborhood Hits	7
SwissProt Accessions	Q14140	Gene names	SERTAD2, KIAA0127
Domain Architecture	No domain graphic available
Description	SERTA domain-containing protein 2 (Transcriptional regulator interacting with the PHD-bromodomain 2) (TRIP-Br2).

SRTD2_MOUSE
θ value	3.19293e-05 (rank : 5)	NC score	0.441711 (rank : 5)
Query Neighborhood Hits	20	Target Neighborhood Hits	21	Shared Neighborhood Hits	7
SwissProt Accessions	Q9JJG5, Q8C609, Q91WL3, Q925E5	Gene names	Sertad2, Kiaa0127
Domain Architecture
Description	SERTA domain-containing protein 2 (Transcriptional regulator interacting with the PHD-bromodomain 2) (TRIP-Br2).

SRTD3_HUMAN
θ value	4.1701e-05 (rank : 6)	NC score	0.353594 (rank : 7)
Query Neighborhood Hits	20	Target Neighborhood Hits	12	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UJW9, Q96CQ2	Gene names	SERTAD3, RBT1
Domain Architecture	No domain graphic available
Description	SERTA domain-containing protein 3 (Replication protein-binding trans- activator) (RPA-binding trans-activator).

SRTD3_MOUSE
θ value	0.000121331 (rank : 7)	NC score	0.329297 (rank : 8)
Query Neighborhood Hits	20	Target Neighborhood Hits	13	Shared Neighborhood Hits	6
SwissProt Accessions	Q9ERC3	Gene names	Sertad3, Rbt1
Domain Architecture	No domain graphic available
Description	SERTA domain-containing protein 3 (Replication protein-binding trans- activator) (RPA-binding trans-activator).

CDCA4_HUMAN
θ value	0.00020696 (rank : 8)	NC score	0.461648 (rank : 4)
Query Neighborhood Hits	20	Target Neighborhood Hits	12	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BXL8, Q8TB18, Q9NWK7	Gene names	CDCA4, HEPP
Domain Architecture
Description	Cell division cycle-associated protein 4 (Hematopoietic progenitor protein).

EAF1_MOUSE
θ value	1.06291 (rank : 9)	NC score	0.052360 (rank : 9)
Query Neighborhood Hits	20	Target Neighborhood Hits	78	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D4C5	Gene names	Eaf1
Domain Architecture	No domain graphic available
Description	ELL-associated factor 1.

SN1L2_HUMAN
θ value	1.06291 (rank : 10)	NC score	0.008054 (rank : 17)
Query Neighborhood Hits	20	Target Neighborhood Hits	964	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H0K1, O94878, Q6AZE2, Q76N03, Q8NCV7, Q96CZ8	Gene names	SNF1LK2, KIAA0781, QIK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SNF1-like kinase 2 (EC 2.7.11.1) (Qin- induced kinase).

PTN23_HUMAN
θ value	1.81305 (rank : 11)	NC score	0.025367 (rank : 13)
Query Neighborhood Hits	20	Target Neighborhood Hits	646	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

PTN23_MOUSE
θ value	2.36792 (rank : 12)	NC score	0.025322 (rank : 14)
Query Neighborhood Hits	20	Target Neighborhood Hits	726	Shared Neighborhood Hits	4
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

WNK2_HUMAN
θ value	2.36792 (rank : 13)	NC score	0.008690 (rank : 16)
Query Neighborhood Hits	20	Target Neighborhood Hits	1407	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

ZN710_MOUSE
θ value	3.0926 (rank : 14)	NC score	0.001779 (rank : 20)
Query Neighborhood Hits	20	Target Neighborhood Hits	749	Shared Neighborhood Hits	2
SwissProt Accessions	Q3U288, Q3U341, Q6P9R3, Q8BJH0, Q8BTL6	Gene names	Znf710, Zfp710
Domain Architecture	No domain graphic available
Description	Zinc finger protein 710.

RUSC1_HUMAN
θ value	4.03905 (rank : 15)	NC score	0.036293 (rank : 12)
Query Neighborhood Hits	20	Target Neighborhood Hits	226	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BVN2, Q9UPY4, Q9Y4T5	Gene names	RUSC1, NESCA
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1 (New molecule containing SH3 at the carboxy-terminus) (Nesca).

RUSC1_MOUSE
θ value	4.03905 (rank : 16)	NC score	0.038510 (rank : 11)
Query Neighborhood Hits	20	Target Neighborhood Hits	206	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BG26, Q6PHT9	Gene names	Rusc1
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1.

SN1L2_MOUSE
θ value	6.88961 (rank : 17)	NC score	0.006428 (rank : 18)
Query Neighborhood Hits	20	Target Neighborhood Hits	944	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CFH6	Gene names	Snf1lk2, Sik2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SNF1-like kinase 2 (EC 2.7.11.1) (Salt-inducible kinase 2).

ACRO_HUMAN
θ value	8.99809 (rank : 18)	NC score	0.002987 (rank : 19)
Query Neighborhood Hits	20	Target Neighborhood Hits	291	Shared Neighborhood Hits	2
SwissProt Accessions	P10323, Q6ICK2	Gene names	ACR, ACRS
Domain Architecture
Description	Acrosin precursor (EC 3.4.21.10) [Contains: Acrosin light chain; Acrosin heavy chain].

EAF1_HUMAN
θ value	8.99809 (rank : 19)	NC score	0.038993 (rank : 10)
Query Neighborhood Hits	20	Target Neighborhood Hits	60	Shared Neighborhood Hits	3
SwissProt Accessions	Q96JC9, Q8IW10	Gene names	EAF1
Domain Architecture	No domain graphic available
Description	ELL-associated factor 1.

MLL4_HUMAN
θ value	8.99809 (rank : 20)	NC score	0.009673 (rank : 15)
Query Neighborhood Hits	20	Target Neighborhood Hits	722	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

Hits sorted by NC score

SRTD1_MOUSE
NC score	0.999962 (rank : 1)	θ value	3.80478e-91 (rank : 1)
Query Neighborhood Hits	20	Target Neighborhood Hits	20	Shared Neighborhood Hits	20
SwissProt Accessions	Q9JL10, Q925E6, Q9D888	Gene names	Sertad1, Sei1
Domain Architecture
Description	SERTA domain-containing protein 1 (Transcriptional regulator interacting with the PHD-bromodomain 1) (TRIP-Br1) (CDK4-binding protein p34SEI1) (SEI-1).

SRTD1_HUMAN
NC score	0.975951 (rank : 2)	θ value	4.22625e-74 (rank : 2)
Query Neighborhood Hits	20	Target Neighborhood Hits	13	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UHV2, Q9BUE7	Gene names	SERTAD1, SEI1
Domain Architecture
Description	SERTA domain-containing protein 1 (Transcriptional regulator interacting with the PHD-bromodomain 1) (TRIP-Br1) (CDK4-binding protein p34SEI1) (SEI-1).

CDCA4_MOUSE
NC score	0.505248 (rank : 3)	θ value	8.97725e-08 (rank : 3)
Query Neighborhood Hits	20	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	Q9CWM2, Q3U1C0, Q921E8, Q99MP6	Gene names	Cdca4, Hepp
Domain Architecture
Description	Cell division cycle-associated protein 4 (Hematopoietic progenitor protein).

CDCA4_HUMAN
NC score	0.461648 (rank : 4)	θ value	0.00020696 (rank : 8)
Query Neighborhood Hits	20	Target Neighborhood Hits	12	Shared Neighborhood Hits	8
SwissProt Accessions	Q9BXL8, Q8TB18, Q9NWK7	Gene names	CDCA4, HEPP
Domain Architecture
Description	Cell division cycle-associated protein 4 (Hematopoietic progenitor protein).

SRTD2_MOUSE
NC score	0.441711 (rank : 5)	θ value	3.19293e-05 (rank : 5)
Query Neighborhood Hits	20	Target Neighborhood Hits	21	Shared Neighborhood Hits	7
SwissProt Accessions	Q9JJG5, Q8C609, Q91WL3, Q925E5	Gene names	Sertad2, Kiaa0127
Domain Architecture
Description	SERTA domain-containing protein 2 (Transcriptional regulator interacting with the PHD-bromodomain 2) (TRIP-Br2).

SRTD2_HUMAN
NC score	0.440015 (rank : 6)	θ value	1.69304e-06 (rank : 4)
Query Neighborhood Hits	20	Target Neighborhood Hits	62	Shared Neighborhood Hits	7
SwissProt Accessions	Q14140	Gene names	SERTAD2, KIAA0127
Domain Architecture	No domain graphic available
Description	SERTA domain-containing protein 2 (Transcriptional regulator interacting with the PHD-bromodomain 2) (TRIP-Br2).

SRTD3_HUMAN
NC score	0.353594 (rank : 7)	θ value	4.1701e-05 (rank : 6)
Query Neighborhood Hits	20	Target Neighborhood Hits	12	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UJW9, Q96CQ2	Gene names	SERTAD3, RBT1
Domain Architecture	No domain graphic available
Description	SERTA domain-containing protein 3 (Replication protein-binding trans- activator) (RPA-binding trans-activator).

SRTD3_MOUSE
NC score	0.329297 (rank : 8)	θ value	0.000121331 (rank : 7)
Query Neighborhood Hits	20	Target Neighborhood Hits	13	Shared Neighborhood Hits	6
SwissProt Accessions	Q9ERC3	Gene names	Sertad3, Rbt1
Domain Architecture	No domain graphic available
Description	SERTA domain-containing protein 3 (Replication protein-binding trans- activator) (RPA-binding trans-activator).

EAF1_MOUSE
NC score	0.052360 (rank : 9)	θ value	1.06291 (rank : 9)
Query Neighborhood Hits	20	Target Neighborhood Hits	78	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D4C5	Gene names	Eaf1
Domain Architecture	No domain graphic available
Description	ELL-associated factor 1.

EAF1_HUMAN
NC score	0.038993 (rank : 10)	θ value	8.99809 (rank : 19)
Query Neighborhood Hits	20	Target Neighborhood Hits	60	Shared Neighborhood Hits	3
SwissProt Accessions	Q96JC9, Q8IW10	Gene names	EAF1
Domain Architecture	No domain graphic available
Description	ELL-associated factor 1.

RUSC1_MOUSE
NC score	0.038510 (rank : 11)	θ value	4.03905 (rank : 16)
Query Neighborhood Hits	20	Target Neighborhood Hits	206	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BG26, Q6PHT9	Gene names	Rusc1
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1.

RUSC1_HUMAN
NC score	0.036293 (rank : 12)	θ value	4.03905 (rank : 15)
Query Neighborhood Hits	20	Target Neighborhood Hits	226	Shared Neighborhood Hits	3
SwissProt Accessions	Q9BVN2, Q9UPY4, Q9Y4T5	Gene names	RUSC1, NESCA
Domain Architecture	No domain graphic available
Description	RUN and SH3 domain-containing protein 1 (New molecule containing SH3 at the carboxy-terminus) (Nesca).

PTN23_HUMAN
NC score	0.025367 (rank : 13)	θ value	1.81305 (rank : 11)
Query Neighborhood Hits	20	Target Neighborhood Hits	646	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

PTN23_MOUSE
NC score	0.025322 (rank : 14)	θ value	2.36792 (rank : 12)
Query Neighborhood Hits	20	Target Neighborhood Hits	726	Shared Neighborhood Hits	4
SwissProt Accessions	Q6PB44, Q69ZJ0, Q8R1Z5, Q923E6	Gene names	Ptpn23, Kiaa1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48).

MLL4_HUMAN
NC score	0.009673 (rank : 15)	θ value	8.99809 (rank : 20)
Query Neighborhood Hits	20	Target Neighborhood Hits	722	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

WNK2_HUMAN
NC score	0.008690 (rank : 16)	θ value	2.36792 (rank : 13)
Query Neighborhood Hits	20	Target Neighborhood Hits	1407	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

SN1L2_HUMAN
NC score	0.008054 (rank : 17)	θ value	1.06291 (rank : 10)
Query Neighborhood Hits	20	Target Neighborhood Hits	964	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H0K1, O94878, Q6AZE2, Q76N03, Q8NCV7, Q96CZ8	Gene names	SNF1LK2, KIAA0781, QIK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SNF1-like kinase 2 (EC 2.7.11.1) (Qin- induced kinase).

SN1L2_MOUSE
NC score	0.006428 (rank : 18)	θ value	6.88961 (rank : 17)
Query Neighborhood Hits	20	Target Neighborhood Hits	944	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CFH6	Gene names	Snf1lk2, Sik2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase SNF1-like kinase 2 (EC 2.7.11.1) (Salt-inducible kinase 2).

ACRO_HUMAN
NC score	0.002987 (rank : 19)	θ value	8.99809 (rank : 18)
Query Neighborhood Hits	20	Target Neighborhood Hits	291	Shared Neighborhood Hits	2
SwissProt Accessions	P10323, Q6ICK2	Gene names	ACR, ACRS
Domain Architecture
Description	Acrosin precursor (EC 3.4.21.10) [Contains: Acrosin light chain; Acrosin heavy chain].

ZN710_MOUSE
NC score	0.001779 (rank : 20)	θ value	3.0926 (rank : 14)
Query Neighborhood Hits	20	Target Neighborhood Hits	749	Shared Neighborhood Hits	2
SwissProt Accessions	Q3U288, Q3U341, Q6P9R3, Q8BJH0, Q8BTL6	Gene names	Znf710, Zfp710
Domain Architecture	No domain graphic available
Description	Zinc finger protein 710.