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Network neighborhood for query Sequence : EYA3_HUMAN

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EYA3_HUMAN
SwissProt Accessions	Q99504, O95463, Q99813	Gene names	EYA3
Domain Architecture
Description	Eyes absent homolog 3 (EC 3.1.3.48).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

EYA3_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	45	Target Neighborhood Hits	45	Shared Neighborhood Hits	45
SwissProt Accessions	Q99504, O95463, Q99813	Gene names	EYA3
Domain Architecture
Description	Eyes absent homolog 3 (EC 3.1.3.48).

EYA3_MOUSE
θ value	0 (rank : 2)	NC score	0.994150 (rank : 2)
Query Neighborhood Hits	45	Target Neighborhood Hits	21	Shared Neighborhood Hits	13
SwissProt Accessions	P97480, P97768	Gene names	Eya3
Domain Architecture
Description	Eyes absent homolog 3 (EC 3.1.3.48).

EYA4_MOUSE
θ value	2.42085e-154 (rank : 3)	NC score	0.977207 (rank : 3)
Query Neighborhood Hits	45	Target Neighborhood Hits	74	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z191	Gene names	Eya4
Domain Architecture
Description	Eyes absent homolog 4 (EC 3.1.3.48).

EYA4_HUMAN
θ value	1.01709e-152 (rank : 4)	NC score	0.966193 (rank : 6)
Query Neighborhood Hits	45	Target Neighborhood Hits	95	Shared Neighborhood Hits	11
SwissProt Accessions	O95677, O95464, O95679, Q8IW39, Q9NTR7	Gene names	EYA4
Domain Architecture
Description	Eyes absent homolog 4 (EC 3.1.3.48).

EYA1_HUMAN
θ value	5.07123e-136 (rank : 5)	NC score	0.965248 (rank : 7)
Query Neighborhood Hits	45	Target Neighborhood Hits	93	Shared Neighborhood Hits	11
SwissProt Accessions	Q99502	Gene names	EYA1
Domain Architecture
Description	Eyes absent homolog 1 (EC 3.1.3.48).

EYA1_MOUSE
θ value	8.9516e-133 (rank : 6)	NC score	0.962100 (rank : 8)
Query Neighborhood Hits	45	Target Neighborhood Hits	108	Shared Neighborhood Hits	9
SwissProt Accessions	P97767, O08818	Gene names	Eya1
Domain Architecture
Description	Eyes absent homolog 1 (EC 3.1.3.48).

EYA2_MOUSE
θ value	4.03687e-117 (rank : 7)	NC score	0.976439 (rank : 4)
Query Neighborhood Hits	45	Target Neighborhood Hits	43	Shared Neighborhood Hits	10
SwissProt Accessions	O08575, P97925	Gene names	Eya2, Eab1
Domain Architecture
Description	Eyes absent homolog 2 (EC 3.1.3.48).

EYA2_HUMAN
θ value	2.37213e-109 (rank : 8)	NC score	0.976038 (rank : 5)
Query Neighborhood Hits	45	Target Neighborhood Hits	28	Shared Neighborhood Hits	8
SwissProt Accessions	O00167, Q5JSW8, Q96CV6, Q96H97, Q99503, Q99812, Q9BWF6, Q9H4S3, Q9H4S9, Q9NPZ4, Q9UIX7	Gene names	EYA2, EAB1
Domain Architecture
Description	Eyes absent homolog 2 (EC 3.1.3.48).

ELF1_MOUSE
θ value	0.125558 (rank : 9)	NC score	0.020747 (rank : 20)
Query Neighborhood Hits	45	Target Neighborhood Hits	139	Shared Neighborhood Hits	4
SwissProt Accessions	Q60775	Gene names	Elf1
Domain Architecture
Description	ETS-related transcription factor Elf-1 (E74-like factor 1).

DNMBP_MOUSE
θ value	0.163984 (rank : 10)	NC score	0.018897 (rank : 23)
Query Neighborhood Hits	45	Target Neighborhood Hits	435	Shared Neighborhood Hits	4
SwissProt Accessions	Q6TXD4, Q6ZQ05, Q8CEW8, Q8R0Y2	Gene names	Dnmbp, Kiaa1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

MMRN1_HUMAN
θ value	0.365318 (rank : 11)	NC score	0.018421 (rank : 25)
Query Neighborhood Hits	45	Target Neighborhood Hits	636	Shared Neighborhood Hits	5
SwissProt Accessions	Q13201, Q6P3T8	Gene names	MMRN1, ECM, EMILIN4, MMRN
Domain Architecture
Description	Multimerin-1 precursor (Endothelial cell multimerin 1) (EMILIN-4) (Elastin microfibril interface located protein 4) (Elastin microfibril interfacer 4).

FOXN4_MOUSE
θ value	0.47712 (rank : 12)	NC score	0.013662 (rank : 28)
Query Neighborhood Hits	45	Target Neighborhood Hits	154	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K3Q3, Q920C0	Gene names	Foxn4
Domain Architecture
Description	Forkhead box protein N4.

ATX2L_MOUSE
θ value	1.38821 (rank : 13)	NC score	0.042488 (rank : 14)
Query Neighborhood Hits	45	Target Neighborhood Hits	401	Shared Neighborhood Hits	10
SwissProt Accessions	Q7TQH0, Q80XN9, Q8K059	Gene names	Atxn2l, A2lp
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein.

HIPK2_MOUSE
θ value	1.81305 (rank : 14)	NC score	0.003228 (rank : 45)
Query Neighborhood Hits	45	Target Neighborhood Hits	871	Shared Neighborhood Hits	6
SwissProt Accessions	Q9QZR5, O88905, Q99P45, Q99P46, Q9D2E6, Q9D474, Q9EQL2, Q9QZR4	Gene names	Hipk2, Nbak1, Stank
Domain Architecture
Description	Homeodomain-interacting protein kinase 2 (EC 2.7.11.1) (Nuclear body- associated kinase 1) (Sialophorin tail-associated nuclear serine/threonine-protein kinase).

JUND_HUMAN
θ value	1.81305 (rank : 15)	NC score	0.019471 (rank : 21)
Query Neighborhood Hits	45	Target Neighborhood Hits	122	Shared Neighborhood Hits	3
SwissProt Accessions	P17535	Gene names	JUND
Domain Architecture
Description	Transcription factor jun-D.

NU214_HUMAN
θ value	1.81305 (rank : 16)	NC score	0.052727 (rank : 13)
Query Neighborhood Hits	45	Target Neighborhood Hits	657	Shared Neighborhood Hits	13
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

PO121_MOUSE
θ value	1.81305 (rank : 17)	NC score	0.019143 (rank : 22)
Query Neighborhood Hits	45	Target Neighborhood Hits	345	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

PPBI_MOUSE
θ value	1.81305 (rank : 18)	NC score	0.012467 (rank : 30)
Query Neighborhood Hits	45	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	P24822	Gene names	Iap, Akp-3, Akp3
Domain Architecture
Description	Intestinal alkaline phosphatase precursor (EC 3.1.3.1) (IAP).

RGS3_MOUSE
θ value	1.81305 (rank : 19)	NC score	0.007966 (rank : 38)
Query Neighborhood Hits	45	Target Neighborhood Hits	1621	Shared Neighborhood Hits	17
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

ZN638_HUMAN
θ value	1.81305 (rank : 20)	NC score	0.017123 (rank : 27)
Query Neighborhood Hits	45	Target Neighborhood Hits	343	Shared Neighborhood Hits	6
SwissProt Accessions	Q14966, Q53R34, Q5XJ05, Q68DP3, Q6P2H2, Q7Z3T7, Q8NF92, Q8TCA1, Q9H2G1, Q9NP37	Gene names	ZNF638, NP220, ZFML
Domain Architecture	No domain graphic available
Description	Zinc finger protein 638 (Nuclear protein 220) (Zinc-finger matrin-like protein) (Cutaneous T-cell lymphoma-associated antigen se33-1) (CTCL tumor antigen se33-1).

LRMP_HUMAN
θ value	2.36792 (rank : 21)	NC score	0.018603 (rank : 24)
Query Neighborhood Hits	45	Target Neighborhood Hits	126	Shared Neighborhood Hits	2
SwissProt Accessions	Q12912, Q8N301	Gene names	LRMP, JAW1
Domain Architecture	No domain graphic available
Description	Lymphoid-restricted membrane protein (Protein Jaw1).

JUND_MOUSE
θ value	3.0926 (rank : 22)	NC score	0.017667 (rank : 26)
Query Neighborhood Hits	45	Target Neighborhood Hits	134	Shared Neighborhood Hits	3
SwissProt Accessions	P15066	Gene names	Jund, Jun-d, Jund1
Domain Architecture
Description	Transcription factor jun-D.

TARA_HUMAN
θ value	3.0926 (rank : 23)	NC score	0.022262 (rank : 19)
Query Neighborhood Hits	45	Target Neighborhood Hits	1626	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TCOF_HUMAN
θ value	3.0926 (rank : 24)	NC score	0.023443 (rank : 18)
Query Neighborhood Hits	45	Target Neighborhood Hits	543	Shared Neighborhood Hits	13
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

ZEP2_MOUSE
θ value	3.0926 (rank : 25)	NC score	0.003319 (rank : 44)
Query Neighborhood Hits	45	Target Neighborhood Hits	964	Shared Neighborhood Hits	8
SwissProt Accessions	Q3UHF7, O55140, Q3UVD4, Q3UVH5	Gene names	Hivep2, Mibp1
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 homolog (Myc intron-binding protein 1) (MIBP-1).

SMRC2_MOUSE
θ value	4.03905 (rank : 26)	NC score	0.012322 (rank : 31)
Query Neighborhood Hits	45	Target Neighborhood Hits	487	Shared Neighborhood Hits	7
SwissProt Accessions	Q6PDG5, Q6P6P3	Gene names	Smarcc2, Baf170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

TR25_MOUSE
θ value	4.03905 (rank : 27)	NC score	0.034525 (rank : 16)
Query Neighborhood Hits	45	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CQI9	Gene names	Thrap6, Trap25
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 6 (Thyroid hormone receptor-associated protein complex 25 kDa component) (Trap25).

ARNT_MOUSE
θ value	5.27518 (rank : 28)	NC score	0.006401 (rank : 40)
Query Neighborhood Hits	45	Target Neighborhood Hits	213	Shared Neighborhood Hits	5
SwissProt Accessions	P53762, Q60661	Gene names	Arnt
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

ATX2L_HUMAN
θ value	5.27518 (rank : 29)	NC score	0.041636 (rank : 15)
Query Neighborhood Hits	45	Target Neighborhood Hits	443	Shared Neighborhood Hits	13
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

CD248_HUMAN
θ value	5.27518 (rank : 30)	NC score	0.004630 (rank : 42)
Query Neighborhood Hits	45	Target Neighborhood Hits	679	Shared Neighborhood Hits	7
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

HXC10_MOUSE
θ value	5.27518 (rank : 31)	NC score	0.002446 (rank : 46)
Query Neighborhood Hits	45	Target Neighborhood Hits	417	Shared Neighborhood Hits	2
SwissProt Accessions	P31257, P31312, Q7TMT7	Gene names	Hoxc10, Hox-3.6, Hoxc-10
Domain Architecture	No domain graphic available
Description	Homeobox protein Hox-C10 (Hox-3.6).

ALMS1_MOUSE
θ value	6.88961 (rank : 32)	NC score	0.013572 (rank : 29)
Query Neighborhood Hits	45	Target Neighborhood Hits	181	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K4E0, Q6A084, Q8C9N9	Gene names	Alms1, Kiaa0328
Domain Architecture	No domain graphic available
Description	Alstrom syndrome protein 1 homolog.

CLSPN_HUMAN
θ value	6.88961 (rank : 33)	NC score	0.008115 (rank : 37)
Query Neighborhood Hits	45	Target Neighborhood Hits	433	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HAW4, Q5VYG0, Q6P6H5, Q8IWI1	Gene names	CLSPN
Domain Architecture	No domain graphic available
Description	Claspin (hClaspin) (Hu-Claspin).

HIPK2_HUMAN
θ value	6.88961 (rank : 34)	NC score	0.002115 (rank : 47)
Query Neighborhood Hits	45	Target Neighborhood Hits	845	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H2X6, Q75MR7, Q8WWI4, Q9H2Y1	Gene names	HIPK2
Domain Architecture
Description	Homeodomain-interacting protein kinase 2 (EC 2.7.11.1) (hHIPk2).

LARP4_HUMAN
θ value	6.88961 (rank : 35)	NC score	0.010424 (rank : 33)
Query Neighborhood Hits	45	Target Neighborhood Hits	69	Shared Neighborhood Hits	2
SwissProt Accessions	Q71RC2, Q5CZ97, Q96NF9	Gene names	LARP4
Domain Architecture	No domain graphic available
Description	La-related protein 4 (La ribonucleoprotein domain family member 4).

LRCH2_HUMAN
θ value	6.88961 (rank : 36)	NC score	0.003388 (rank : 43)
Query Neighborhood Hits	45	Target Neighborhood Hits	315	Shared Neighborhood Hits	3
SwissProt Accessions	Q5VUJ6, Q9HA88, Q9P233	Gene names	LRCH2, KIAA1495
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and calponin homology domain-containing protein 2.

MDC1_HUMAN
θ value	6.88961 (rank : 37)	NC score	0.010611 (rank : 32)
Query Neighborhood Hits	45	Target Neighborhood Hits	1446	Shared Neighborhood Hits	16
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

ARP5_HUMAN
θ value	8.99809 (rank : 38)	NC score	0.008339 (rank : 36)
Query Neighborhood Hits	45	Target Neighborhood Hits	107	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H9F9, Q86WF7, Q8IUY5, Q8N724, Q9BRN0, Q9BVB7	Gene names	ACTR5, ARP5
Domain Architecture	No domain graphic available
Description	Actin-related protein 5 (hARP5) (Sarcoma antigen NY-SAR-16).

ARP5_MOUSE
θ value	8.99809 (rank : 39)	NC score	0.008520 (rank : 35)
Query Neighborhood Hits	45	Target Neighborhood Hits	116	Shared Neighborhood Hits	3
SwissProt Accessions	Q80US4, Q8BL26	Gene names	Actr5
Domain Architecture	No domain graphic available
Description	Actin-related protein 5.

MYO9B_HUMAN
θ value	8.99809 (rank : 40)	NC score	0.001475 (rank : 48)
Query Neighborhood Hits	45	Target Neighborhood Hits	641	Shared Neighborhood Hits	7
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

PDZD2_HUMAN
θ value	8.99809 (rank : 41)	NC score	0.005032 (rank : 41)
Query Neighborhood Hits	45	Target Neighborhood Hits	772	Shared Neighborhood Hits	10
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

PTPRS_HUMAN
θ value	8.99809 (rank : 42)	NC score	0.000183 (rank : 49)
Query Neighborhood Hits	45	Target Neighborhood Hits	472	Shared Neighborhood Hits	2
SwissProt Accessions	Q13332, O75255, O75870, Q15718, Q16341	Gene names	PTPRS
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase S precursor (EC 3.1.3.48) (R-PTP-S) (Protein-tyrosine phosphatase sigma) (R-PTP-sigma).

SMRC2_HUMAN
θ value	8.99809 (rank : 43)	NC score	0.010168 (rank : 34)
Query Neighborhood Hits	45	Target Neighborhood Hits	499	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TAQ2, Q92923, Q96E12, Q96GY4	Gene names	SMARCC2, BAF170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

TCF20_MOUSE
θ value	8.99809 (rank : 44)	NC score	0.007379 (rank : 39)
Query Neighborhood Hits	45	Target Neighborhood Hits	396	Shared Neighborhood Hits	8
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

TR25_HUMAN
θ value	8.99809 (rank : 45)	NC score	0.026000 (rank : 17)
Query Neighborhood Hits	45	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	Q96HR3	Gene names	THRAP6, TRAP25
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 6 (Thyroid hormone receptor-associated protein complex 25 kDa component) (Trap25) (TRAP/Mediator complex component TRAP25) (MED30).

EWS_HUMAN
θ value	θ > 10 (rank : 46)	NC score	0.083706 (rank : 10)
Query Neighborhood Hits	45	Target Neighborhood Hits	249	Shared Neighborhood Hits	7
SwissProt Accessions	Q01844, Q92635	Gene names	EWSR1, EWS
Domain Architecture
Description	RNA-binding protein EWS (EWS oncogene) (Ewing sarcoma breakpoint region 1 protein).

EWS_MOUSE
θ value	θ > 10 (rank : 47)	NC score	0.083163 (rank : 11)
Query Neighborhood Hits	45	Target Neighborhood Hits	271	Shared Neighborhood Hits	7
SwissProt Accessions	Q61545	Gene names	Ewsr1, Ews, Ewsh
Domain Architecture
Description	RNA-binding protein EWS.

FUS_HUMAN
θ value	θ > 10 (rank : 48)	NC score	0.079883 (rank : 12)
Query Neighborhood Hits	45	Target Neighborhood Hits	179	Shared Neighborhood Hits	6
SwissProt Accessions	P35637	Gene names	FUS, TLS
Domain Architecture
Description	RNA-binding protein FUS (Oncogene FUS) (Oncogene TLS) (Translocated in liposarcoma protein) (POMp75) (75 kDa DNA-pairing protein).

FUS_MOUSE
θ value	θ > 10 (rank : 49)	NC score	0.090533 (rank : 9)
Query Neighborhood Hits	45	Target Neighborhood Hits	154	Shared Neighborhood Hits	6
SwissProt Accessions	P56959	Gene names	Fus
Domain Architecture
Description	RNA-binding protein FUS (Pigpen protein).

Hits sorted by NC score

EYA3_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	45	Target Neighborhood Hits	45	Shared Neighborhood Hits	45
SwissProt Accessions	Q99504, O95463, Q99813	Gene names	EYA3
Domain Architecture
Description	Eyes absent homolog 3 (EC 3.1.3.48).

EYA3_MOUSE
NC score	0.994150 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	45	Target Neighborhood Hits	21	Shared Neighborhood Hits	13
SwissProt Accessions	P97480, P97768	Gene names	Eya3
Domain Architecture
Description	Eyes absent homolog 3 (EC 3.1.3.48).

EYA4_MOUSE
NC score	0.977207 (rank : 3)	θ value	2.42085e-154 (rank : 3)
Query Neighborhood Hits	45	Target Neighborhood Hits	74	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z191	Gene names	Eya4
Domain Architecture
Description	Eyes absent homolog 4 (EC 3.1.3.48).

EYA2_MOUSE
NC score	0.976439 (rank : 4)	θ value	4.03687e-117 (rank : 7)
Query Neighborhood Hits	45	Target Neighborhood Hits	43	Shared Neighborhood Hits	10
SwissProt Accessions	O08575, P97925	Gene names	Eya2, Eab1
Domain Architecture
Description	Eyes absent homolog 2 (EC 3.1.3.48).

EYA2_HUMAN
NC score	0.976038 (rank : 5)	θ value	2.37213e-109 (rank : 8)
Query Neighborhood Hits	45	Target Neighborhood Hits	28	Shared Neighborhood Hits	8
SwissProt Accessions	O00167, Q5JSW8, Q96CV6, Q96H97, Q99503, Q99812, Q9BWF6, Q9H4S3, Q9H4S9, Q9NPZ4, Q9UIX7	Gene names	EYA2, EAB1
Domain Architecture
Description	Eyes absent homolog 2 (EC 3.1.3.48).

EYA4_HUMAN
NC score	0.966193 (rank : 6)	θ value	1.01709e-152 (rank : 4)
Query Neighborhood Hits	45	Target Neighborhood Hits	95	Shared Neighborhood Hits	11
SwissProt Accessions	O95677, O95464, O95679, Q8IW39, Q9NTR7	Gene names	EYA4
Domain Architecture
Description	Eyes absent homolog 4 (EC 3.1.3.48).

EYA1_HUMAN
NC score	0.965248 (rank : 7)	θ value	5.07123e-136 (rank : 5)
Query Neighborhood Hits	45	Target Neighborhood Hits	93	Shared Neighborhood Hits	11
SwissProt Accessions	Q99502	Gene names	EYA1
Domain Architecture
Description	Eyes absent homolog 1 (EC 3.1.3.48).

EYA1_MOUSE
NC score	0.962100 (rank : 8)	θ value	8.9516e-133 (rank : 6)
Query Neighborhood Hits	45	Target Neighborhood Hits	108	Shared Neighborhood Hits	9
SwissProt Accessions	P97767, O08818	Gene names	Eya1
Domain Architecture
Description	Eyes absent homolog 1 (EC 3.1.3.48).

FUS_MOUSE
NC score	0.090533 (rank : 9)	θ value	θ > 10 (rank : 49)
Query Neighborhood Hits	45	Target Neighborhood Hits	154	Shared Neighborhood Hits	6
SwissProt Accessions	P56959	Gene names	Fus
Domain Architecture
Description	RNA-binding protein FUS (Pigpen protein).

EWS_HUMAN
NC score	0.083706 (rank : 10)	θ value	θ > 10 (rank : 46)
Query Neighborhood Hits	45	Target Neighborhood Hits	249	Shared Neighborhood Hits	7
SwissProt Accessions	Q01844, Q92635	Gene names	EWSR1, EWS
Domain Architecture
Description	RNA-binding protein EWS (EWS oncogene) (Ewing sarcoma breakpoint region 1 protein).

EWS_MOUSE
NC score	0.083163 (rank : 11)	θ value	θ > 10 (rank : 47)
Query Neighborhood Hits	45	Target Neighborhood Hits	271	Shared Neighborhood Hits	7
SwissProt Accessions	Q61545	Gene names	Ewsr1, Ews, Ewsh
Domain Architecture
Description	RNA-binding protein EWS.

FUS_HUMAN
NC score	0.079883 (rank : 12)	θ value	θ > 10 (rank : 48)
Query Neighborhood Hits	45	Target Neighborhood Hits	179	Shared Neighborhood Hits	6
SwissProt Accessions	P35637	Gene names	FUS, TLS
Domain Architecture
Description	RNA-binding protein FUS (Oncogene FUS) (Oncogene TLS) (Translocated in liposarcoma protein) (POMp75) (75 kDa DNA-pairing protein).

NU214_HUMAN
NC score	0.052727 (rank : 13)	θ value	1.81305 (rank : 16)
Query Neighborhood Hits	45	Target Neighborhood Hits	657	Shared Neighborhood Hits	13
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

ATX2L_MOUSE
NC score	0.042488 (rank : 14)	θ value	1.38821 (rank : 13)
Query Neighborhood Hits	45	Target Neighborhood Hits	401	Shared Neighborhood Hits	10
SwissProt Accessions	Q7TQH0, Q80XN9, Q8K059	Gene names	Atxn2l, A2lp
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein.

ATX2L_HUMAN
NC score	0.041636 (rank : 15)	θ value	5.27518 (rank : 29)
Query Neighborhood Hits	45	Target Neighborhood Hits	443	Shared Neighborhood Hits	13
SwissProt Accessions	Q8WWM7, O95135, Q6NVJ8, Q6PJW6, Q8IU61, Q8IU95, Q8WWM3, Q8WWM4, Q8WWM5, Q8WWM6, Q99703	Gene names	ATXN2L, A2D, A2LG, A2LP, A2RP
Domain Architecture	No domain graphic available
Description	Ataxin-2-like protein (Ataxin-2 domain protein) (Ataxin-2-related protein).

TR25_MOUSE
NC score	0.034525 (rank : 16)	θ value	4.03905 (rank : 27)
Query Neighborhood Hits	45	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CQI9	Gene names	Thrap6, Trap25
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 6 (Thyroid hormone receptor-associated protein complex 25 kDa component) (Trap25).

TR25_HUMAN
NC score	0.026000 (rank : 17)	θ value	8.99809 (rank : 45)
Query Neighborhood Hits	45	Target Neighborhood Hits	8	Shared Neighborhood Hits	4
SwissProt Accessions	Q96HR3	Gene names	THRAP6, TRAP25
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 6 (Thyroid hormone receptor-associated protein complex 25 kDa component) (Trap25) (TRAP/Mediator complex component TRAP25) (MED30).

TCOF_HUMAN
NC score	0.023443 (rank : 18)	θ value	3.0926 (rank : 24)
Query Neighborhood Hits	45	Target Neighborhood Hits	543	Shared Neighborhood Hits	13
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

TARA_HUMAN
NC score	0.022262 (rank : 19)	θ value	3.0926 (rank : 23)
Query Neighborhood Hits	45	Target Neighborhood Hits	1626	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

ELF1_MOUSE
NC score	0.020747 (rank : 20)	θ value	0.125558 (rank : 9)
Query Neighborhood Hits	45	Target Neighborhood Hits	139	Shared Neighborhood Hits	4
SwissProt Accessions	Q60775	Gene names	Elf1
Domain Architecture
Description	ETS-related transcription factor Elf-1 (E74-like factor 1).

JUND_HUMAN
NC score	0.019471 (rank : 21)	θ value	1.81305 (rank : 15)
Query Neighborhood Hits	45	Target Neighborhood Hits	122	Shared Neighborhood Hits	3
SwissProt Accessions	P17535	Gene names	JUND
Domain Architecture
Description	Transcription factor jun-D.

PO121_MOUSE
NC score	0.019143 (rank : 22)	θ value	1.81305 (rank : 17)
Query Neighborhood Hits	45	Target Neighborhood Hits	345	Shared Neighborhood Hits	11
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

DNMBP_MOUSE
NC score	0.018897 (rank : 23)	θ value	0.163984 (rank : 10)
Query Neighborhood Hits	45	Target Neighborhood Hits	435	Shared Neighborhood Hits	4
SwissProt Accessions	Q6TXD4, Q6ZQ05, Q8CEW8, Q8R0Y2	Gene names	Dnmbp, Kiaa1010
Domain Architecture	No domain graphic available
Description	Dynamin-binding protein (Scaffold protein Tuba).

LRMP_HUMAN
NC score	0.018603 (rank : 24)	θ value	2.36792 (rank : 21)
Query Neighborhood Hits	45	Target Neighborhood Hits	126	Shared Neighborhood Hits	2
SwissProt Accessions	Q12912, Q8N301	Gene names	LRMP, JAW1
Domain Architecture	No domain graphic available
Description	Lymphoid-restricted membrane protein (Protein Jaw1).

MMRN1_HUMAN
NC score	0.018421 (rank : 25)	θ value	0.365318 (rank : 11)
Query Neighborhood Hits	45	Target Neighborhood Hits	636	Shared Neighborhood Hits	5
SwissProt Accessions	Q13201, Q6P3T8	Gene names	MMRN1, ECM, EMILIN4, MMRN
Domain Architecture
Description	Multimerin-1 precursor (Endothelial cell multimerin 1) (EMILIN-4) (Elastin microfibril interface located protein 4) (Elastin microfibril interfacer 4).

JUND_MOUSE
NC score	0.017667 (rank : 26)	θ value	3.0926 (rank : 22)
Query Neighborhood Hits	45	Target Neighborhood Hits	134	Shared Neighborhood Hits	3
SwissProt Accessions	P15066	Gene names	Jund, Jun-d, Jund1
Domain Architecture
Description	Transcription factor jun-D.

ZN638_HUMAN
NC score	0.017123 (rank : 27)	θ value	1.81305 (rank : 20)
Query Neighborhood Hits	45	Target Neighborhood Hits	343	Shared Neighborhood Hits	6
SwissProt Accessions	Q14966, Q53R34, Q5XJ05, Q68DP3, Q6P2H2, Q7Z3T7, Q8NF92, Q8TCA1, Q9H2G1, Q9NP37	Gene names	ZNF638, NP220, ZFML
Domain Architecture	No domain graphic available
Description	Zinc finger protein 638 (Nuclear protein 220) (Zinc-finger matrin-like protein) (Cutaneous T-cell lymphoma-associated antigen se33-1) (CTCL tumor antigen se33-1).

FOXN4_MOUSE
NC score	0.013662 (rank : 28)	θ value	0.47712 (rank : 12)
Query Neighborhood Hits	45	Target Neighborhood Hits	154	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K3Q3, Q920C0	Gene names	Foxn4
Domain Architecture
Description	Forkhead box protein N4.

ALMS1_MOUSE
NC score	0.013572 (rank : 29)	θ value	6.88961 (rank : 32)
Query Neighborhood Hits	45	Target Neighborhood Hits	181	Shared Neighborhood Hits	5
SwissProt Accessions	Q8K4E0, Q6A084, Q8C9N9	Gene names	Alms1, Kiaa0328
Domain Architecture	No domain graphic available
Description	Alstrom syndrome protein 1 homolog.

PPBI_MOUSE
NC score	0.012467 (rank : 30)	θ value	1.81305 (rank : 18)
Query Neighborhood Hits	45	Target Neighborhood Hits	19	Shared Neighborhood Hits	2
SwissProt Accessions	P24822	Gene names	Iap, Akp-3, Akp3
Domain Architecture
Description	Intestinal alkaline phosphatase precursor (EC 3.1.3.1) (IAP).

SMRC2_MOUSE
NC score	0.012322 (rank : 31)	θ value	4.03905 (rank : 26)
Query Neighborhood Hits	45	Target Neighborhood Hits	487	Shared Neighborhood Hits	7
SwissProt Accessions	Q6PDG5, Q6P6P3	Gene names	Smarcc2, Baf170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

MDC1_HUMAN
NC score	0.010611 (rank : 32)	θ value	6.88961 (rank : 37)
Query Neighborhood Hits	45	Target Neighborhood Hits	1446	Shared Neighborhood Hits	16
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

LARP4_HUMAN
NC score	0.010424 (rank : 33)	θ value	6.88961 (rank : 35)
Query Neighborhood Hits	45	Target Neighborhood Hits	69	Shared Neighborhood Hits	2
SwissProt Accessions	Q71RC2, Q5CZ97, Q96NF9	Gene names	LARP4
Domain Architecture	No domain graphic available
Description	La-related protein 4 (La ribonucleoprotein domain family member 4).

SMRC2_HUMAN
NC score	0.010168 (rank : 34)	θ value	8.99809 (rank : 43)
Query Neighborhood Hits	45	Target Neighborhood Hits	499	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TAQ2, Q92923, Q96E12, Q96GY4	Gene names	SMARCC2, BAF170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

ARP5_MOUSE
NC score	0.008520 (rank : 35)	θ value	8.99809 (rank : 39)
Query Neighborhood Hits	45	Target Neighborhood Hits	116	Shared Neighborhood Hits	3
SwissProt Accessions	Q80US4, Q8BL26	Gene names	Actr5
Domain Architecture	No domain graphic available
Description	Actin-related protein 5.

ARP5_HUMAN
NC score	0.008339 (rank : 36)	θ value	8.99809 (rank : 38)
Query Neighborhood Hits	45	Target Neighborhood Hits	107	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H9F9, Q86WF7, Q8IUY5, Q8N724, Q9BRN0, Q9BVB7	Gene names	ACTR5, ARP5
Domain Architecture	No domain graphic available
Description	Actin-related protein 5 (hARP5) (Sarcoma antigen NY-SAR-16).

CLSPN_HUMAN
NC score	0.008115 (rank : 37)	θ value	6.88961 (rank : 33)
Query Neighborhood Hits	45	Target Neighborhood Hits	433	Shared Neighborhood Hits	3
SwissProt Accessions	Q9HAW4, Q5VYG0, Q6P6H5, Q8IWI1	Gene names	CLSPN
Domain Architecture	No domain graphic available
Description	Claspin (hClaspin) (Hu-Claspin).

RGS3_MOUSE
NC score	0.007966 (rank : 38)	θ value	1.81305 (rank : 19)
Query Neighborhood Hits	45	Target Neighborhood Hits	1621	Shared Neighborhood Hits	17
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

TCF20_MOUSE
NC score	0.007379 (rank : 39)	θ value	8.99809 (rank : 44)
Query Neighborhood Hits	45	Target Neighborhood Hits	396	Shared Neighborhood Hits	8
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

ARNT_MOUSE
NC score	0.006401 (rank : 40)	θ value	5.27518 (rank : 28)
Query Neighborhood Hits	45	Target Neighborhood Hits	213	Shared Neighborhood Hits	5
SwissProt Accessions	P53762, Q60661	Gene names	Arnt
Domain Architecture
Description	Aryl hydrocarbon receptor nuclear translocator (ARNT protein) (Dioxin receptor, nuclear translocator) (Hypoxia-inducible factor 1 beta) (HIF-1 beta).

PDZD2_HUMAN
NC score	0.005032 (rank : 41)	θ value	8.99809 (rank : 41)
Query Neighborhood Hits	45	Target Neighborhood Hits	772	Shared Neighborhood Hits	10
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

CD248_HUMAN
NC score	0.004630 (rank : 42)	θ value	5.27518 (rank : 30)
Query Neighborhood Hits	45	Target Neighborhood Hits	679	Shared Neighborhood Hits	7
SwissProt Accessions	Q9HCU0, Q3SX55, Q96KB6	Gene names	CD248, CD164L1, TEM1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

LRCH2_HUMAN
NC score	0.003388 (rank : 43)	θ value	6.88961 (rank : 36)
Query Neighborhood Hits	45	Target Neighborhood Hits	315	Shared Neighborhood Hits	3
SwissProt Accessions	Q5VUJ6, Q9HA88, Q9P233	Gene names	LRCH2, KIAA1495
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and calponin homology domain-containing protein 2.

ZEP2_MOUSE
NC score	0.003319 (rank : 44)	θ value	3.0926 (rank : 25)
Query Neighborhood Hits	45	Target Neighborhood Hits	964	Shared Neighborhood Hits	8
SwissProt Accessions	Q3UHF7, O55140, Q3UVD4, Q3UVH5	Gene names	Hivep2, Mibp1
Domain Architecture	No domain graphic available
Description	Human immunodeficiency virus type I enhancer-binding protein 2 homolog (Myc intron-binding protein 1) (MIBP-1).

HIPK2_MOUSE
NC score	0.003228 (rank : 45)	θ value	1.81305 (rank : 14)
Query Neighborhood Hits	45	Target Neighborhood Hits	871	Shared Neighborhood Hits	6
SwissProt Accessions	Q9QZR5, O88905, Q99P45, Q99P46, Q9D2E6, Q9D474, Q9EQL2, Q9QZR4	Gene names	Hipk2, Nbak1, Stank
Domain Architecture
Description	Homeodomain-interacting protein kinase 2 (EC 2.7.11.1) (Nuclear body- associated kinase 1) (Sialophorin tail-associated nuclear serine/threonine-protein kinase).

HXC10_MOUSE
NC score	0.002446 (rank : 46)	θ value	5.27518 (rank : 31)
Query Neighborhood Hits	45	Target Neighborhood Hits	417	Shared Neighborhood Hits	2
SwissProt Accessions	P31257, P31312, Q7TMT7	Gene names	Hoxc10, Hox-3.6, Hoxc-10
Domain Architecture	No domain graphic available
Description	Homeobox protein Hox-C10 (Hox-3.6).

HIPK2_HUMAN
NC score	0.002115 (rank : 47)	θ value	6.88961 (rank : 34)
Query Neighborhood Hits	45	Target Neighborhood Hits	845	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H2X6, Q75MR7, Q8WWI4, Q9H2Y1	Gene names	HIPK2
Domain Architecture
Description	Homeodomain-interacting protein kinase 2 (EC 2.7.11.1) (hHIPk2).

MYO9B_HUMAN
NC score	0.001475 (rank : 48)	θ value	8.99809 (rank : 40)
Query Neighborhood Hits	45	Target Neighborhood Hits	641	Shared Neighborhood Hits	7
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

PTPRS_HUMAN
NC score	0.000183 (rank : 49)	θ value	8.99809 (rank : 42)
Query Neighborhood Hits	45	Target Neighborhood Hits	472	Shared Neighborhood Hits	2
SwissProt Accessions	Q13332, O75255, O75870, Q15718, Q16341	Gene names	PTPRS
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase S precursor (EC 3.1.3.48) (R-PTP-S) (Protein-tyrosine phosphatase sigma) (R-PTP-sigma).