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Network neighborhood for query Sequence : PPGB_HUMAN

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PPGB_HUMAN
SwissProt Accessions	P10619, Q5JZH1, Q96KJ2, Q9BR08, Q9BW68	Gene names	PPGB
Domain Architecture
Description	Lysosomal protective protein precursor (EC 3.4.16.5) (Cathepsin A) (Carboxypeptidase C) (Protective protein for beta-galactosidase) [Contains: Lysosomal protective protein 32 kDa chain; Lysosomal protective protein 20 kDa chain].
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PPGB_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	10
SwissProt Accessions	P10619, Q5JZH1, Q96KJ2, Q9BR08, Q9BW68	Gene names	PPGB
Domain Architecture
Description	Lysosomal protective protein precursor (EC 3.4.16.5) (Cathepsin A) (Carboxypeptidase C) (Protective protein for beta-galactosidase) [Contains: Lysosomal protective protein 32 kDa chain; Lysosomal protective protein 20 kDa chain].

PPGB_MOUSE
θ value	0 (rank : 2)	NC score	0.997998 (rank : 2)
Query Neighborhood Hits	10	Target Neighborhood Hits	9	Shared Neighborhood Hits	6
SwissProt Accessions	P16675, Q8VEF6	Gene names	Ppgb
Domain Architecture
Description	Lysosomal protective protein precursor (EC 3.4.16.5) (Cathepsin A) (Carboxypeptidase C) (Protective protein for beta-galactosidase) [Contains: Lysosomal protective protein 32 kDa chain; Lysosomal protective protein 20 kDa chain].

CPVL_HUMAN
θ value	2.58187e-47 (rank : 3)	NC score	0.855758 (rank : 3)
Query Neighborhood Hits	10	Target Neighborhood Hits	11	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H3G5, Q6UX20, Q8NBL7, Q96AR7, Q9HB41	Gene names	CPVL, VLP
Domain Architecture
Description	Probable serine carboxypeptidase CPVL precursor (EC 3.4.16.-) (Carboxypeptidase, vitellogenic-like) (Vitellogenic carboxypeptidase- like protein) (VCP-like protein) (HVLP).

RISC_MOUSE
θ value	1.6852e-22 (rank : 4)	NC score	0.686454 (rank : 4)
Query Neighborhood Hits	10	Target Neighborhood Hits	12	Shared Neighborhood Hits	5
SwissProt Accessions	Q920A5	Gene names	Scpep1, Risc
Domain Architecture
Description	Retinoid-inducible serine carboxypeptidase precursor (EC 3.4.16.-) (Serine carboxypeptidase 1).

RISC_HUMAN
θ value	1.058e-16 (rank : 5)	NC score	0.648191 (rank : 5)
Query Neighborhood Hits	10	Target Neighborhood Hits	8	Shared Neighborhood Hits	5
SwissProt Accessions	Q9HB40, Q96A94, Q9H3F0	Gene names	SCPEP1, RISC, SCP1
Domain Architecture
Description	Retinoid-inducible serine carboxypeptidase precursor (EC 3.4.16.-) (Serine carboxypeptidase 1).

SO3A1_HUMAN
θ value	1.38821 (rank : 6)	NC score	0.023932 (rank : 7)
Query Neighborhood Hits	10	Target Neighborhood Hits	54	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UIG8, Q9BW73, Q9GZV2	Gene names	SLCO3A1, OATPD, SLC21A11
Domain Architecture
Description	Solute carrier organic anion transporter family member 3A1 (Solute carrier family 21 member 11) (Sodium-independent organic anion transporter D) (Organic anion-transporting polypeptide D) (OATP-D) (Organic anion transporter polypeptide-related protein 3) (OATP-RP3) (OATPRP3) (PGE1 transporter).

SO3A1_MOUSE
θ value	1.38821 (rank : 7)	NC score	0.023939 (rank : 6)
Query Neighborhood Hits	10	Target Neighborhood Hits	59	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R3L5, Q9CTV3, Q9JKV0	Gene names	Slco3a1, Oatpd, Slc21a11
Domain Architecture
Description	Solute carrier organic anion transporter family member 3A1 (Solute carrier family 21 member 11) (Sodium-independent organic anion transporter D) (Organic anion-transporting polypeptide D) (OATP-D) (MJAM).

ACES_MOUSE
θ value	5.27518 (rank : 8)	NC score	0.011661 (rank : 10)
Query Neighborhood Hits	10	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	P21836	Gene names	Ache
Domain Architecture
Description	Acetylcholinesterase precursor (EC 3.1.1.7) (AChE).

ACES_HUMAN
θ value	8.99809 (rank : 9)	NC score	0.013793 (rank : 8)
Query Neighborhood Hits	10	Target Neighborhood Hits	35	Shared Neighborhood Hits	4
SwissProt Accessions	P22303, Q16169, Q86TM9, Q9BXP7	Gene names	ACHE
Domain Architecture
Description	Acetylcholinesterase precursor (EC 3.1.1.7) (AChE).

Hits sorted by NC score

PPGB_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	10	Target Neighborhood Hits	10	Shared Neighborhood Hits	10
SwissProt Accessions	P10619, Q5JZH1, Q96KJ2, Q9BR08, Q9BW68	Gene names	PPGB
Domain Architecture
Description	Lysosomal protective protein precursor (EC 3.4.16.5) (Cathepsin A) (Carboxypeptidase C) (Protective protein for beta-galactosidase) [Contains: Lysosomal protective protein 32 kDa chain; Lysosomal protective protein 20 kDa chain].

PPGB_MOUSE
NC score	0.997998 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	10	Target Neighborhood Hits	9	Shared Neighborhood Hits	6
SwissProt Accessions	P16675, Q8VEF6	Gene names	Ppgb
Domain Architecture
Description	Lysosomal protective protein precursor (EC 3.4.16.5) (Cathepsin A) (Carboxypeptidase C) (Protective protein for beta-galactosidase) [Contains: Lysosomal protective protein 32 kDa chain; Lysosomal protective protein 20 kDa chain].

CPVL_HUMAN
NC score	0.855758 (rank : 3)	θ value	2.58187e-47 (rank : 3)
Query Neighborhood Hits	10	Target Neighborhood Hits	11	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H3G5, Q6UX20, Q8NBL7, Q96AR7, Q9HB41	Gene names	CPVL, VLP
Domain Architecture
Description	Probable serine carboxypeptidase CPVL precursor (EC 3.4.16.-) (Carboxypeptidase, vitellogenic-like) (Vitellogenic carboxypeptidase- like protein) (VCP-like protein) (HVLP).

RISC_MOUSE
NC score	0.686454 (rank : 4)	θ value	1.6852e-22 (rank : 4)
Query Neighborhood Hits	10	Target Neighborhood Hits	12	Shared Neighborhood Hits	5
SwissProt Accessions	Q920A5	Gene names	Scpep1, Risc
Domain Architecture
Description	Retinoid-inducible serine carboxypeptidase precursor (EC 3.4.16.-) (Serine carboxypeptidase 1).

RISC_HUMAN
NC score	0.648191 (rank : 5)	θ value	1.058e-16 (rank : 5)
Query Neighborhood Hits	10	Target Neighborhood Hits	8	Shared Neighborhood Hits	5
SwissProt Accessions	Q9HB40, Q96A94, Q9H3F0	Gene names	SCPEP1, RISC, SCP1
Domain Architecture
Description	Retinoid-inducible serine carboxypeptidase precursor (EC 3.4.16.-) (Serine carboxypeptidase 1).

SO3A1_MOUSE
NC score	0.023939 (rank : 6)	θ value	1.38821 (rank : 7)
Query Neighborhood Hits	10	Target Neighborhood Hits	59	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R3L5, Q9CTV3, Q9JKV0	Gene names	Slco3a1, Oatpd, Slc21a11
Domain Architecture
Description	Solute carrier organic anion transporter family member 3A1 (Solute carrier family 21 member 11) (Sodium-independent organic anion transporter D) (Organic anion-transporting polypeptide D) (OATP-D) (MJAM).

SO3A1_HUMAN
NC score	0.023932 (rank : 7)	θ value	1.38821 (rank : 6)
Query Neighborhood Hits	10	Target Neighborhood Hits	54	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UIG8, Q9BW73, Q9GZV2	Gene names	SLCO3A1, OATPD, SLC21A11
Domain Architecture
Description	Solute carrier organic anion transporter family member 3A1 (Solute carrier family 21 member 11) (Sodium-independent organic anion transporter D) (Organic anion-transporting polypeptide D) (OATP-D) (Organic anion transporter polypeptide-related protein 3) (OATP-RP3) (OATPRP3) (PGE1 transporter).

ACES_HUMAN
NC score	0.013793 (rank : 8)	θ value	8.99809 (rank : 9)
Query Neighborhood Hits	10	Target Neighborhood Hits	35	Shared Neighborhood Hits	4
SwissProt Accessions	P22303, Q16169, Q86TM9, Q9BXP7	Gene names	ACHE
Domain Architecture
Description	Acetylcholinesterase precursor (EC 3.1.1.7) (AChE).

ACES_MOUSE
NC score	0.011661 (rank : 10)	θ value	5.27518 (rank : 8)
Query Neighborhood Hits	10	Target Neighborhood Hits	29	Shared Neighborhood Hits	3
SwissProt Accessions	P21836	Gene names	Ache
Domain Architecture
Description	Acetylcholinesterase precursor (EC 3.1.1.7) (AChE).