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Network neighborhood for query Sequence : PPGB_MOUSE

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PPGB_MOUSE
SwissProt Accessions	P16675, Q8VEF6	Gene names	Ppgb
Domain Architecture
Description	Lysosomal protective protein precursor (EC 3.4.16.5) (Cathepsin A) (Carboxypeptidase C) (Protective protein for beta-galactosidase) [Contains: Lysosomal protective protein 32 kDa chain; Lysosomal protective protein 20 kDa chain].
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

PPGB_HUMAN
θ value	0 (rank : 1)	NC score	0.997998 (rank : 2)
Query Neighborhood Hits	9	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	P10619, Q5JZH1, Q96KJ2, Q9BR08, Q9BW68	Gene names	PPGB
Domain Architecture
Description	Lysosomal protective protein precursor (EC 3.4.16.5) (Cathepsin A) (Carboxypeptidase C) (Protective protein for beta-galactosidase) [Contains: Lysosomal protective protein 32 kDa chain; Lysosomal protective protein 20 kDa chain].

PPGB_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	9	Target Neighborhood Hits	9	Shared Neighborhood Hits	9
SwissProt Accessions	P16675, Q8VEF6	Gene names	Ppgb
Domain Architecture
Description	Lysosomal protective protein precursor (EC 3.4.16.5) (Cathepsin A) (Carboxypeptidase C) (Protective protein for beta-galactosidase) [Contains: Lysosomal protective protein 32 kDa chain; Lysosomal protective protein 20 kDa chain].

CPVL_HUMAN
θ value	1.08474e-45 (rank : 3)	NC score	0.850307 (rank : 3)
Query Neighborhood Hits	9	Target Neighborhood Hits	11	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H3G5, Q6UX20, Q8NBL7, Q96AR7, Q9HB41	Gene names	CPVL, VLP
Domain Architecture
Description	Probable serine carboxypeptidase CPVL precursor (EC 3.4.16.-) (Carboxypeptidase, vitellogenic-like) (Vitellogenic carboxypeptidase- like protein) (VCP-like protein) (HVLP).

RISC_MOUSE
θ value	5.42112e-21 (rank : 4)	NC score	0.676128 (rank : 4)
Query Neighborhood Hits	9	Target Neighborhood Hits	12	Shared Neighborhood Hits	5
SwissProt Accessions	Q920A5	Gene names	Scpep1, Risc
Domain Architecture
Description	Retinoid-inducible serine carboxypeptidase precursor (EC 3.4.16.-) (Serine carboxypeptidase 1).

RISC_HUMAN
θ value	3.40345e-15 (rank : 5)	NC score	0.637225 (rank : 5)
Query Neighborhood Hits	9	Target Neighborhood Hits	8	Shared Neighborhood Hits	5
SwissProt Accessions	Q9HB40, Q96A94, Q9H3F0	Gene names	SCPEP1, RISC, SCP1
Domain Architecture
Description	Retinoid-inducible serine carboxypeptidase precursor (EC 3.4.16.-) (Serine carboxypeptidase 1).

POMT2_HUMAN
θ value	2.36792 (rank : 6)	NC score	0.035198 (rank : 6)
Query Neighborhood Hits	9	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UKY4, Q9NSG6, Q9P1W0, Q9P1W2	Gene names	POMT2
Domain Architecture
Description	Protein O-mannosyl-transferase 2 (EC 2.4.1.109) (Dolichyl-phosphate- mannose--protein mannosyltransferase 2).

POMT2_MOUSE
θ value	3.0926 (rank : 7)	NC score	0.033889 (rank : 7)
Query Neighborhood Hits	9	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BGQ4, Q8R4Z0	Gene names	Pomt2
Domain Architecture
Description	Protein O-mannosyl-transferase 2 (EC 2.4.1.109) (Dolichyl-phosphate- mannose--protein mannosyltransferase 2).

KLF5_MOUSE
θ value	4.03905 (rank : 8)	NC score	0.002636 (rank : 9)
Query Neighborhood Hits	9	Target Neighborhood Hits	726	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z0Z7, Q9JMI2	Gene names	Klf5, Bteb2, Iklf
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 5 (Intestinal-enriched krueppel-like factor) (Transcription factor BTEB2) (Basic transcription element-binding protein 2) (BTE-binding protein 2).

ACES_HUMAN
θ value	6.88961 (rank : 9)	NC score	0.010125 (rank : 8)
Query Neighborhood Hits	9	Target Neighborhood Hits	35	Shared Neighborhood Hits	3
SwissProt Accessions	P22303, Q16169, Q86TM9, Q9BXP7	Gene names	ACHE
Domain Architecture
Description	Acetylcholinesterase precursor (EC 3.1.1.7) (AChE).

Hits sorted by NC score

PPGB_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	9	Target Neighborhood Hits	9	Shared Neighborhood Hits	9
SwissProt Accessions	P16675, Q8VEF6	Gene names	Ppgb
Domain Architecture
Description	Lysosomal protective protein precursor (EC 3.4.16.5) (Cathepsin A) (Carboxypeptidase C) (Protective protein for beta-galactosidase) [Contains: Lysosomal protective protein 32 kDa chain; Lysosomal protective protein 20 kDa chain].

PPGB_HUMAN
NC score	0.997998 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	9	Target Neighborhood Hits	10	Shared Neighborhood Hits	6
SwissProt Accessions	P10619, Q5JZH1, Q96KJ2, Q9BR08, Q9BW68	Gene names	PPGB
Domain Architecture
Description	Lysosomal protective protein precursor (EC 3.4.16.5) (Cathepsin A) (Carboxypeptidase C) (Protective protein for beta-galactosidase) [Contains: Lysosomal protective protein 32 kDa chain; Lysosomal protective protein 20 kDa chain].

CPVL_HUMAN
NC score	0.850307 (rank : 3)	θ value	1.08474e-45 (rank : 3)
Query Neighborhood Hits	9	Target Neighborhood Hits	11	Shared Neighborhood Hits	5
SwissProt Accessions	Q9H3G5, Q6UX20, Q8NBL7, Q96AR7, Q9HB41	Gene names	CPVL, VLP
Domain Architecture
Description	Probable serine carboxypeptidase CPVL precursor (EC 3.4.16.-) (Carboxypeptidase, vitellogenic-like) (Vitellogenic carboxypeptidase- like protein) (VCP-like protein) (HVLP).

RISC_MOUSE
NC score	0.676128 (rank : 4)	θ value	5.42112e-21 (rank : 4)
Query Neighborhood Hits	9	Target Neighborhood Hits	12	Shared Neighborhood Hits	5
SwissProt Accessions	Q920A5	Gene names	Scpep1, Risc
Domain Architecture
Description	Retinoid-inducible serine carboxypeptidase precursor (EC 3.4.16.-) (Serine carboxypeptidase 1).

RISC_HUMAN
NC score	0.637225 (rank : 5)	θ value	3.40345e-15 (rank : 5)
Query Neighborhood Hits	9	Target Neighborhood Hits	8	Shared Neighborhood Hits	5
SwissProt Accessions	Q9HB40, Q96A94, Q9H3F0	Gene names	SCPEP1, RISC, SCP1
Domain Architecture
Description	Retinoid-inducible serine carboxypeptidase precursor (EC 3.4.16.-) (Serine carboxypeptidase 1).

POMT2_HUMAN
NC score	0.035198 (rank : 6)	θ value	2.36792 (rank : 6)
Query Neighborhood Hits	9	Target Neighborhood Hits	17	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UKY4, Q9NSG6, Q9P1W0, Q9P1W2	Gene names	POMT2
Domain Architecture
Description	Protein O-mannosyl-transferase 2 (EC 2.4.1.109) (Dolichyl-phosphate- mannose--protein mannosyltransferase 2).

POMT2_MOUSE
NC score	0.033889 (rank : 7)	θ value	3.0926 (rank : 7)
Query Neighborhood Hits	9	Target Neighborhood Hits	26	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BGQ4, Q8R4Z0	Gene names	Pomt2
Domain Architecture
Description	Protein O-mannosyl-transferase 2 (EC 2.4.1.109) (Dolichyl-phosphate- mannose--protein mannosyltransferase 2).

ACES_HUMAN
NC score	0.010125 (rank : 8)	θ value	6.88961 (rank : 9)
Query Neighborhood Hits	9	Target Neighborhood Hits	35	Shared Neighborhood Hits	3
SwissProt Accessions	P22303, Q16169, Q86TM9, Q9BXP7	Gene names	ACHE
Domain Architecture
Description	Acetylcholinesterase precursor (EC 3.1.1.7) (AChE).

KLF5_MOUSE
NC score	0.002636 (rank : 9)	θ value	4.03905 (rank : 8)
Query Neighborhood Hits	9	Target Neighborhood Hits	726	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Z0Z7, Q9JMI2	Gene names	Klf5, Bteb2, Iklf
Domain Architecture	No domain graphic available
Description	Krueppel-like factor 5 (Intestinal-enriched krueppel-like factor) (Transcription factor BTEB2) (Basic transcription element-binding protein 2) (BTE-binding protein 2).