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Network neighborhood for query Sequence : CPVL_HUMAN

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CPVL_HUMAN
SwissProt Accessions	Q9H3G5, Q6UX20, Q8NBL7, Q96AR7, Q9HB41	Gene names	CPVL, VLP
Domain Architecture
Description	Probable serine carboxypeptidase CPVL precursor (EC 3.4.16.-) (Carboxypeptidase, vitellogenic-like) (Vitellogenic carboxypeptidase- like protein) (VCP-like protein) (HVLP).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

CPVL_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	11	Target Neighborhood Hits	11	Shared Neighborhood Hits	11
SwissProt Accessions	Q9H3G5, Q6UX20, Q8NBL7, Q96AR7, Q9HB41	Gene names	CPVL, VLP
Domain Architecture
Description	Probable serine carboxypeptidase CPVL precursor (EC 3.4.16.-) (Carboxypeptidase, vitellogenic-like) (Vitellogenic carboxypeptidase- like protein) (VCP-like protein) (HVLP).

PPGB_HUMAN
θ value	2.58187e-47 (rank : 2)	NC score	0.855758 (rank : 2)
Query Neighborhood Hits	11	Target Neighborhood Hits	10	Shared Neighborhood Hits	5
SwissProt Accessions	P10619, Q5JZH1, Q96KJ2, Q9BR08, Q9BW68	Gene names	PPGB
Domain Architecture
Description	Lysosomal protective protein precursor (EC 3.4.16.5) (Cathepsin A) (Carboxypeptidase C) (Protective protein for beta-galactosidase) [Contains: Lysosomal protective protein 32 kDa chain; Lysosomal protective protein 20 kDa chain].

PPGB_MOUSE
θ value	1.08474e-45 (rank : 3)	NC score	0.850307 (rank : 3)
Query Neighborhood Hits	11	Target Neighborhood Hits	9	Shared Neighborhood Hits	5
SwissProt Accessions	P16675, Q8VEF6	Gene names	Ppgb
Domain Architecture
Description	Lysosomal protective protein precursor (EC 3.4.16.5) (Cathepsin A) (Carboxypeptidase C) (Protective protein for beta-galactosidase) [Contains: Lysosomal protective protein 32 kDa chain; Lysosomal protective protein 20 kDa chain].

RISC_MOUSE
θ value	2.05049e-36 (rank : 4)	NC score	0.817003 (rank : 4)
Query Neighborhood Hits	11	Target Neighborhood Hits	12	Shared Neighborhood Hits	5
SwissProt Accessions	Q920A5	Gene names	Scpep1, Risc
Domain Architecture
Description	Retinoid-inducible serine carboxypeptidase precursor (EC 3.4.16.-) (Serine carboxypeptidase 1).

RISC_HUMAN
θ value	2.50655e-34 (rank : 5)	NC score	0.799210 (rank : 5)
Query Neighborhood Hits	11	Target Neighborhood Hits	8	Shared Neighborhood Hits	5
SwissProt Accessions	Q9HB40, Q96A94, Q9H3F0	Gene names	SCPEP1, RISC, SCP1
Domain Architecture
Description	Retinoid-inducible serine carboxypeptidase precursor (EC 3.4.16.-) (Serine carboxypeptidase 1).

ENOG_MOUSE
θ value	5.27518 (rank : 6)	NC score	0.018258 (rank : 7)
Query Neighborhood Hits	11	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	P17183	Gene names	Eno2, Eno-2
Domain Architecture
Description	Gamma-enolase (EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase) (Neural enolase) (Neuron-specific enolase) (NSE) (Enolase 2).

TSPY1_HUMAN
θ value	5.27518 (rank : 7)	NC score	0.018297 (rank : 6)
Query Neighborhood Hits	11	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	Q01534, O00216, P09002, Q9UNN7	Gene names	TSPY1, TSPY
Domain Architecture
Description	Testis-specific Y-encoded protein 1.

ECE2_HUMAN
θ value	6.88961 (rank : 8)	NC score	0.009434 (rank : 9)
Query Neighborhood Hits	11	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	O60344, Q96NX3, Q96NX4	Gene names	ECE2, KIAA0604
Domain Architecture
Description	Endothelin-converting enzyme 2 (EC 3.4.24.71) (ECE-2).

ENOG_HUMAN
θ value	6.88961 (rank : 9)	NC score	0.017207 (rank : 8)
Query Neighborhood Hits	11	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	P09104, Q96J33	Gene names	ENO2
Domain Architecture
Description	Gamma-enolase (EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase) (Neural enolase) (Neuron-specific enolase) (NSE) (Enolase 2).

LHX2_MOUSE
θ value	6.88961 (rank : 10)	NC score	0.007943 (rank : 10)
Query Neighborhood Hits	11	Target Neighborhood Hits	431	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z0S2	Gene names	Lhx2
Domain Architecture
Description	LIM/homeobox protein Lhx2.

LHX2_HUMAN
θ value	8.99809 (rank : 11)	NC score	0.007262 (rank : 11)
Query Neighborhood Hits	11	Target Neighborhood Hits	432	Shared Neighborhood Hits	3
SwissProt Accessions	P50458, O95860, Q8N1Z3	Gene names	LHX2, LH2
Domain Architecture
Description	LIM/homeobox protein Lhx2 (Homeobox protein LH-2).

Hits sorted by NC score

CPVL_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	11	Target Neighborhood Hits	11	Shared Neighborhood Hits	11
SwissProt Accessions	Q9H3G5, Q6UX20, Q8NBL7, Q96AR7, Q9HB41	Gene names	CPVL, VLP
Domain Architecture
Description	Probable serine carboxypeptidase CPVL precursor (EC 3.4.16.-) (Carboxypeptidase, vitellogenic-like) (Vitellogenic carboxypeptidase- like protein) (VCP-like protein) (HVLP).

PPGB_HUMAN
NC score	0.855758 (rank : 2)	θ value	2.58187e-47 (rank : 2)
Query Neighborhood Hits	11	Target Neighborhood Hits	10	Shared Neighborhood Hits	5
SwissProt Accessions	P10619, Q5JZH1, Q96KJ2, Q9BR08, Q9BW68	Gene names	PPGB
Domain Architecture
Description	Lysosomal protective protein precursor (EC 3.4.16.5) (Cathepsin A) (Carboxypeptidase C) (Protective protein for beta-galactosidase) [Contains: Lysosomal protective protein 32 kDa chain; Lysosomal protective protein 20 kDa chain].

PPGB_MOUSE
NC score	0.850307 (rank : 3)	θ value	1.08474e-45 (rank : 3)
Query Neighborhood Hits	11	Target Neighborhood Hits	9	Shared Neighborhood Hits	5
SwissProt Accessions	P16675, Q8VEF6	Gene names	Ppgb
Domain Architecture
Description	Lysosomal protective protein precursor (EC 3.4.16.5) (Cathepsin A) (Carboxypeptidase C) (Protective protein for beta-galactosidase) [Contains: Lysosomal protective protein 32 kDa chain; Lysosomal protective protein 20 kDa chain].

RISC_MOUSE
NC score	0.817003 (rank : 4)	θ value	2.05049e-36 (rank : 4)
Query Neighborhood Hits	11	Target Neighborhood Hits	12	Shared Neighborhood Hits	5
SwissProt Accessions	Q920A5	Gene names	Scpep1, Risc
Domain Architecture
Description	Retinoid-inducible serine carboxypeptidase precursor (EC 3.4.16.-) (Serine carboxypeptidase 1).

RISC_HUMAN
NC score	0.799210 (rank : 5)	θ value	2.50655e-34 (rank : 5)
Query Neighborhood Hits	11	Target Neighborhood Hits	8	Shared Neighborhood Hits	5
SwissProt Accessions	Q9HB40, Q96A94, Q9H3F0	Gene names	SCPEP1, RISC, SCP1
Domain Architecture
Description	Retinoid-inducible serine carboxypeptidase precursor (EC 3.4.16.-) (Serine carboxypeptidase 1).

TSPY1_HUMAN
NC score	0.018297 (rank : 6)	θ value	5.27518 (rank : 7)
Query Neighborhood Hits	11	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	Q01534, O00216, P09002, Q9UNN7	Gene names	TSPY1, TSPY
Domain Architecture
Description	Testis-specific Y-encoded protein 1.

ENOG_MOUSE
NC score	0.018258 (rank : 7)	θ value	5.27518 (rank : 6)
Query Neighborhood Hits	11	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	P17183	Gene names	Eno2, Eno-2
Domain Architecture
Description	Gamma-enolase (EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase) (Neural enolase) (Neuron-specific enolase) (NSE) (Enolase 2).

ENOG_HUMAN
NC score	0.017207 (rank : 8)	θ value	6.88961 (rank : 9)
Query Neighborhood Hits	11	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	P09104, Q96J33	Gene names	ENO2
Domain Architecture
Description	Gamma-enolase (EC 4.2.1.11) (2-phospho-D-glycerate hydro-lyase) (Neural enolase) (Neuron-specific enolase) (NSE) (Enolase 2).

ECE2_HUMAN
NC score	0.009434 (rank : 9)	θ value	6.88961 (rank : 8)
Query Neighborhood Hits	11	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	O60344, Q96NX3, Q96NX4	Gene names	ECE2, KIAA0604
Domain Architecture
Description	Endothelin-converting enzyme 2 (EC 3.4.24.71) (ECE-2).

LHX2_MOUSE
NC score	0.007943 (rank : 10)	θ value	6.88961 (rank : 10)
Query Neighborhood Hits	11	Target Neighborhood Hits	431	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z0S2	Gene names	Lhx2
Domain Architecture
Description	LIM/homeobox protein Lhx2.

LHX2_HUMAN
NC score	0.007262 (rank : 11)	θ value	8.99809 (rank : 11)
Query Neighborhood Hits	11	Target Neighborhood Hits	432	Shared Neighborhood Hits	3
SwissProt Accessions	P50458, O95860, Q8N1Z3	Gene names	LHX2, LH2
Domain Architecture
Description	LIM/homeobox protein Lhx2 (Homeobox protein LH-2).