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Network neighborhood for query Sequence : SETB1_MOUSE

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SETB1_MOUSE
SwissProt Accessions	O88974, Q922K1	Gene names	Setdb1, Eset
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SETB1_HUMAN
θ value	0 (rank : 1)	NC score	0.977838 (rank : 2)
Query Neighborhood Hits	150	Target Neighborhood Hits	141	Shared Neighborhood Hits	62
SwissProt Accessions	Q15047, Q96GM9	Gene names	SETDB1, KIAA0067
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

SETB1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	150	Target Neighborhood Hits	150	Shared Neighborhood Hits	150
SwissProt Accessions	O88974, Q922K1	Gene names	Setdb1, Eset
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

SETB2_HUMAN
θ value	3.35642e-63 (rank : 3)	NC score	0.857298 (rank : 3)
Query Neighborhood Hits	150	Target Neighborhood Hits	62	Shared Neighborhood Hits	26
SwissProt Accessions	Q96T68, Q86UD6, Q96AI6	Gene names	SETDB2, CLLD8
Domain Architecture
Description	Probable histone-lysine N-methyltransferase, H3 lysine-9 specific (EC 2.1.1.43) (Histone H3-K9 methyltransferase) (H3-K9-HMTase) (SET domain bifurcated 2) (Chronic lymphocytic leukemia deletion region gene 8 protein).

EHMT2_HUMAN
θ value	1.05554e-24 (rank : 4)	NC score	0.361204 (rank : 18)
Query Neighborhood Hits	150	Target Neighborhood Hits	498	Shared Neighborhood Hits	33
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

EHMT2_MOUSE
θ value	4.01107e-24 (rank : 5)	NC score	0.359751 (rank : 19)
Query Neighborhood Hits	150	Target Neighborhood Hits	750	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

EHMT1_HUMAN
θ value	1.16704e-23 (rank : 6)	NC score	0.352339 (rank : 20)
Query Neighborhood Hits	150	Target Neighborhood Hits	417	Shared Neighborhood Hits	31
SwissProt Accessions	Q9H9B1, Q8TCN7, Q96F53, Q96JF1, Q96KH4	Gene names	EHMT1, EUHMTASE1, KIAA1876
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a- like protein 1) (GLP1).

SUV91_HUMAN
θ value	1.2077e-20 (rank : 7)	NC score	0.654981 (rank : 4)
Query Neighborhood Hits	150	Target Neighborhood Hits	63	Shared Neighborhood Hits	23
SwissProt Accessions	O43463, Q53G60, Q6FHK6	Gene names	SUV39H1, SUV39H
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 1 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1).

SUV91_MOUSE
θ value	5.99374e-20 (rank : 8)	NC score	0.646271 (rank : 5)
Query Neighborhood Hits	150	Target Neighborhood Hits	69	Shared Neighborhood Hits	23
SwissProt Accessions	O54864, Q9JLC7, Q9JLP8	Gene names	Suv39h1, Suv39h
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 1 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1) (Position-effect variegation 3-9 homolog).

SUV92_MOUSE
θ value	2.35696e-16 (rank : 9)	NC score	0.628047 (rank : 6)
Query Neighborhood Hits	150	Target Neighborhood Hits	59	Shared Neighborhood Hits	23
SwissProt Accessions	Q9EQQ0, Q9CUK3, Q9JLP7	Gene names	Suv39h2
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2).

SUV92_HUMAN
θ value	3.40345e-15 (rank : 10)	NC score	0.627124 (rank : 7)
Query Neighborhood Hits	150	Target Neighborhood Hits	54	Shared Neighborhood Hits	23
SwissProt Accessions	Q9H5I1	Gene names	SUV39H2
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2).

MLL4_HUMAN
θ value	3.89403e-11 (rank : 11)	NC score	0.436026 (rank : 14)
Query Neighborhood Hits	150	Target Neighborhood Hits	722	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

SETD2_HUMAN
θ value	1.9326e-10 (rank : 12)	NC score	0.520230 (rank : 8)
Query Neighborhood Hits	150	Target Neighborhood Hits	412	Shared Neighborhood Hits	43
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

HRX_HUMAN
θ value	9.59137e-10 (rank : 13)	NC score	0.429521 (rank : 15)
Query Neighborhood Hits	150	Target Neighborhood Hits	825	Shared Neighborhood Hits	59
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

MLL2_HUMAN
θ value	1.63604e-09 (rank : 14)	NC score	0.342439 (rank : 21)
Query Neighborhood Hits	150	Target Neighborhood Hits	1788	Shared Neighborhood Hits	87
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MLL3_HUMAN
θ value	3.08544e-08 (rank : 15)	NC score	0.315423 (rank : 23)
Query Neighborhood Hits	150	Target Neighborhood Hits	1644	Shared Neighborhood Hits	70
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

NSD1_HUMAN
θ value	3.08544e-08 (rank : 16)	NC score	0.429519 (rank : 16)
Query Neighborhood Hits	150	Target Neighborhood Hits	427	Shared Neighborhood Hits	45
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

NSD1_MOUSE
θ value	3.08544e-08 (rank : 17)	NC score	0.427981 (rank : 17)
Query Neighborhood Hits	150	Target Neighborhood Hits	472	Shared Neighborhood Hits	46
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

MLL3_MOUSE
θ value	6.87365e-08 (rank : 18)	NC score	0.328323 (rank : 22)
Query Neighborhood Hits	150	Target Neighborhood Hits	1399	Shared Neighborhood Hits	71
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

SET1A_HUMAN
θ value	1.99992e-07 (rank : 19)	NC score	0.464990 (rank : 12)
Query Neighborhood Hits	150	Target Neighborhood Hits	690	Shared Neighborhood Hits	63
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

EZH1_HUMAN
θ value	1.29631e-06 (rank : 20)	NC score	0.474638 (rank : 9)
Query Neighborhood Hits	150	Target Neighborhood Hits	121	Shared Neighborhood Hits	27
SwissProt Accessions	Q92800, O43287, Q14459	Gene names	EZH1, KIAA0388
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

EZH1_MOUSE
θ value	1.29631e-06 (rank : 21)	NC score	0.474207 (rank : 10)
Query Neighborhood Hits	150	Target Neighborhood Hits	126	Shared Neighborhood Hits	27
SwissProt Accessions	P70351, Q9R089	Gene names	Ezh1, Enx2
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

EZH2_HUMAN
θ value	6.43352e-06 (rank : 22)	NC score	0.469258 (rank : 11)
Query Neighborhood Hits	150	Target Neighborhood Hits	84	Shared Neighborhood Hits	26
SwissProt Accessions	Q15910, Q15755, Q92857	Gene names	EZH2
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

EZH2_MOUSE
θ value	3.19293e-05 (rank : 23)	NC score	0.461803 (rank : 13)
Query Neighborhood Hits	150	Target Neighborhood Hits	86	Shared Neighborhood Hits	26
SwissProt Accessions	Q61188, Q9R090	Gene names	Ezh2, Enx1h
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

NFH_MOUSE
θ value	0.0563607 (rank : 24)	NC score	0.047707 (rank : 86)
Query Neighborhood Hits	150	Target Neighborhood Hits	2247	Shared Neighborhood Hits	80
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

PI5PA_HUMAN
θ value	0.125558 (rank : 25)	NC score	0.056478 (rank : 57)
Query Neighborhood Hits	150	Target Neighborhood Hits	749	Shared Neighborhood Hits	45
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

SON_HUMAN
θ value	0.125558 (rank : 26)	NC score	0.057271 (rank : 54)
Query Neighborhood Hits	150	Target Neighborhood Hits	1568	Shared Neighborhood Hits	58
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

ANK2_HUMAN
θ value	0.163984 (rank : 27)	NC score	0.063321 (rank : 39)
Query Neighborhood Hits	150	Target Neighborhood Hits	1615	Shared Neighborhood Hits	63
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

JPH3_HUMAN
θ value	0.163984 (rank : 28)	NC score	0.025962 (rank : 124)
Query Neighborhood Hits	150	Target Neighborhood Hits	80	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WXH2, Q8N471, Q9HDC3, Q9HDC4	Gene names	JPH3, JP3
Domain Architecture
Description	Junctophilin-3 (Junctophilin type 3) (JP-3).

BAZ2B_HUMAN
θ value	0.21417 (rank : 29)	NC score	0.076518 (rank : 28)
Query Neighborhood Hits	150	Target Neighborhood Hits	803	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

EPAS1_MOUSE
θ value	0.21417 (rank : 30)	NC score	0.022215 (rank : 146)
Query Neighborhood Hits	150	Target Neighborhood Hits	94	Shared Neighborhood Hits	5
SwissProt Accessions	P97481, O08787, O55046	Gene names	Epas1, Hif2a
Domain Architecture
Description	Endothelial PAS domain-containing protein 1 (EPAS-1) (Hypoxia- inducible factor 2 alpha) (HIF-2 alpha) (HIF2 alpha) (HIF-1 alpha-like factor) (MHLF) (HIF-related factor) (HRF).

GOGA1_HUMAN
θ value	0.21417 (rank : 31)	NC score	0.031949 (rank : 108)
Query Neighborhood Hits	150	Target Neighborhood Hits	1222	Shared Neighborhood Hits	42
SwissProt Accessions	Q92805, Q8IYZ9	Gene names	GOLGA1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

LTBP3_MOUSE
θ value	0.21417 (rank : 32)	NC score	0.032594 (rank : 106)
Query Neighborhood Hits	150	Target Neighborhood Hits	475	Shared Neighborhood Hits	20
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

TARSH_HUMAN
θ value	0.21417 (rank : 33)	NC score	0.073849 (rank : 29)
Query Neighborhood Hits	150	Target Neighborhood Hits	768	Shared Neighborhood Hits	41
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

VPS72_MOUSE
θ value	0.21417 (rank : 34)	NC score	0.082024 (rank : 27)
Query Neighborhood Hits	150	Target Neighborhood Hits	286	Shared Neighborhood Hits	15
SwissProt Accessions	Q62481, Q3U2N4, Q810A9, Q99K81	Gene names	Vps72, Tcfl1, Yl1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

MYH3_HUMAN
θ value	0.279714 (rank : 35)	NC score	0.025067 (rank : 128)
Query Neighborhood Hits	150	Target Neighborhood Hits	1660	Shared Neighborhood Hits	46
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

TTF2_MOUSE
θ value	0.279714 (rank : 36)	NC score	0.027323 (rank : 120)
Query Neighborhood Hits	150	Target Neighborhood Hits	364	Shared Neighborhood Hits	15
SwissProt Accessions	Q5NC05, Q5M924	Gene names	Ttf2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2).

CEL_HUMAN
θ value	0.365318 (rank : 37)	NC score	0.029180 (rank : 117)
Query Neighborhood Hits	150	Target Neighborhood Hits	896	Shared Neighborhood Hits	33
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

SPTN4_HUMAN
θ value	0.365318 (rank : 38)	NC score	0.033585 (rank : 105)
Query Neighborhood Hits	150	Target Neighborhood Hits	570	Shared Neighborhood Hits	35
SwissProt Accessions	Q9H254, Q9H1K7, Q9H1K8, Q9H1K9, Q9H3G8, Q9HCD0	Gene names	SPTBN4, KIAA1642, SPTBN3
Domain Architecture
Description	Spectrin beta chain, brain 3 (Spectrin, non-erythroid beta chain 3) (Beta-IV spectrin).

CIC_MOUSE
θ value	0.47712 (rank : 39)	NC score	0.047287 (rank : 87)
Query Neighborhood Hits	150	Target Neighborhood Hits	742	Shared Neighborhood Hits	48
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

LTBP3_HUMAN
θ value	0.47712 (rank : 40)	NC score	0.030038 (rank : 113)
Query Neighborhood Hits	150	Target Neighborhood Hits	502	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

MAP4_HUMAN
θ value	0.47712 (rank : 41)	NC score	0.053575 (rank : 64)
Query Neighborhood Hits	150	Target Neighborhood Hits	428	Shared Neighborhood Hits	29
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

RRBP1_MOUSE
θ value	0.47712 (rank : 42)	NC score	0.031892 (rank : 109)
Query Neighborhood Hits	150	Target Neighborhood Hits	1650	Shared Neighborhood Hits	56
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

CT2NL_MOUSE
θ value	0.62314 (rank : 43)	NC score	0.041434 (rank : 94)
Query Neighborhood Hits	150	Target Neighborhood Hits	902	Shared Neighborhood Hits	45
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

NOTC2_HUMAN
θ value	0.62314 (rank : 44)	NC score	0.039645 (rank : 97)
Query Neighborhood Hits	150	Target Neighborhood Hits	1113	Shared Neighborhood Hits	46
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

OR2J1_HUMAN
θ value	0.62314 (rank : 45)	NC score	0.002127 (rank : 196)
Query Neighborhood Hits	150	Target Neighborhood Hits	758	Shared Neighborhood Hits	4
SwissProt Accessions	Q9GZK6, Q9GZK1	Gene names	OR2J1
Domain Architecture
Description	Olfactory receptor 2J1 (Olfactory receptor 6-5) (OR6-5) (Hs6M1-4).

KIF4A_MOUSE
θ value	0.813845 (rank : 46)	NC score	0.024230 (rank : 135)
Query Neighborhood Hits	150	Target Neighborhood Hits	1033	Shared Neighborhood Hits	45
SwissProt Accessions	P33174	Gene names	Kif4a, Kif4, Kns4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

LTBP4_MOUSE
θ value	0.813845 (rank : 47)	NC score	0.025138 (rank : 127)
Query Neighborhood Hits	150	Target Neighborhood Hits	607	Shared Neighborhood Hits	28
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

AKAP2_HUMAN
θ value	1.06291 (rank : 48)	NC score	0.031211 (rank : 112)
Query Neighborhood Hits	150	Target Neighborhood Hits	507	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Y2D5, Q9UG26	Gene names	AKAP2, KIAA0920
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2).

CENPF_HUMAN
θ value	1.06291 (rank : 49)	NC score	0.025398 (rank : 126)
Query Neighborhood Hits	150	Target Neighborhood Hits	1932	Shared Neighborhood Hits	56
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

CRSP7_HUMAN
θ value	1.06291 (rank : 50)	NC score	0.045205 (rank : 90)
Query Neighborhood Hits	150	Target Neighborhood Hits	247	Shared Neighborhood Hits	14
SwissProt Accessions	O95402	Gene names	CRSP7, ARC70
Domain Architecture
Description	CRSP complex subunit 7 (Cofactor required for Sp1 transcriptional activation subunit 7) (Transcriptional coactivator CRSP70) (Activator- recruited cofactor 70 kDa component) (ARC70).

GRIN1_HUMAN
θ value	1.06291 (rank : 51)	NC score	0.040503 (rank : 96)
Query Neighborhood Hits	150	Target Neighborhood Hits	681	Shared Neighborhood Hits	29
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

MYCD_HUMAN
θ value	1.06291 (rank : 52)	NC score	0.043569 (rank : 91)
Query Neighborhood Hits	150	Target Neighborhood Hits	167	Shared Neighborhood Hits	15
SwissProt Accessions	Q8IZQ8, Q8N7Q1	Gene names	MYOCD, MYCD
Domain Architecture
Description	Myocardin.

NCOA6_HUMAN
θ value	1.06291 (rank : 53)	NC score	0.054932 (rank : 60)
Query Neighborhood Hits	150	Target Neighborhood Hits	1202	Shared Neighborhood Hits	44
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

SOX15_HUMAN
θ value	1.06291 (rank : 54)	NC score	0.020263 (rank : 154)
Query Neighborhood Hits	150	Target Neighborhood Hits	134	Shared Neighborhood Hits	9
SwissProt Accessions	O60248, P35717, Q9Y6W7	Gene names	SOX15, SOX12, SOX20, SOX26, SOX27
Domain Architecture
Description	SOX-15 protein (SOX-20 protein) (SOX-12 protein).

ALMS1_MOUSE
θ value	1.38821 (rank : 55)	NC score	0.029786 (rank : 115)
Query Neighborhood Hits	150	Target Neighborhood Hits	181	Shared Neighborhood Hits	13
SwissProt Accessions	Q8K4E0, Q6A084, Q8C9N9	Gene names	Alms1, Kiaa0328
Domain Architecture	No domain graphic available
Description	Alstrom syndrome protein 1 homolog.

MILK2_HUMAN
θ value	1.38821 (rank : 56)	NC score	0.048181 (rank : 85)
Query Neighborhood Hits	150	Target Neighborhood Hits	457	Shared Neighborhood Hits	42
SwissProt Accessions	Q8IY33, Q7RTP4, Q7Z655, Q8TEQ4, Q9H5F9	Gene names
Domain Architecture
Description	MICAL-like protein 2.

RGS3_HUMAN
θ value	1.38821 (rank : 57)	NC score	0.032456 (rank : 107)
Query Neighborhood Hits	150	Target Neighborhood Hits	1375	Shared Neighborhood Hits	39
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

SHC2_MOUSE
θ value	1.38821 (rank : 58)	NC score	0.014417 (rank : 179)
Query Neighborhood Hits	150	Target Neighborhood Hits	144	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BMC3	Gene names	Shc2, Sck, ShcB
Domain Architecture
Description	SHC-transforming protein 2 (SH2 domain protein C2) (Src homology 2 domain-containing-transforming protein C2) (Protein Sck) (Protein Sli).

FYCO1_MOUSE
θ value	1.81305 (rank : 59)	NC score	0.024126 (rank : 137)
Query Neighborhood Hits	150	Target Neighborhood Hits	1059	Shared Neighborhood Hits	36
SwissProt Accessions	Q8VDC1, Q3V385, Q7TMT0, Q8BJN2	Gene names	Fyco1
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1.

NELL2_HUMAN
θ value	1.81305 (rank : 60)	NC score	0.020938 (rank : 150)
Query Neighborhood Hits	150	Target Neighborhood Hits	449	Shared Neighborhood Hits	14
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

NELL2_MOUSE
θ value	1.81305 (rank : 61)	NC score	0.020892 (rank : 151)
Query Neighborhood Hits	150	Target Neighborhood Hits	436	Shared Neighborhood Hits	15
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

NRX2A_HUMAN
θ value	1.81305 (rank : 62)	NC score	0.022158 (rank : 147)
Query Neighborhood Hits	150	Target Neighborhood Hits	614	Shared Neighborhood Hits	29
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

NRX2B_HUMAN
θ value	1.81305 (rank : 63)	NC score	0.028960 (rank : 118)
Query Neighborhood Hits	150	Target Neighborhood Hits	481	Shared Neighborhood Hits	24
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

SOX17_MOUSE
θ value	1.81305 (rank : 64)	NC score	0.018862 (rank : 168)
Query Neighborhood Hits	150	Target Neighborhood Hits	223	Shared Neighborhood Hits	16
SwissProt Accessions	Q61473, Q61472, Q62248	Gene names	Sox17, Sox-17
Domain Architecture
Description	Transcription factor SOX-17.

TTC16_HUMAN
θ value	1.81305 (rank : 65)	NC score	0.026951 (rank : 122)
Query Neighborhood Hits	150	Target Neighborhood Hits	417	Shared Neighborhood Hits	15
SwissProt Accessions	Q8NEE8, Q5JU66, Q96M72	Gene names	TTC16
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 16 (TPR repeat protein 16).

VPS72_HUMAN
θ value	1.81305 (rank : 66)	NC score	0.066822 (rank : 31)
Query Neighborhood Hits	150	Target Neighborhood Hits	274	Shared Neighborhood Hits	13
SwissProt Accessions	Q15906, Q53GJ2, Q5U0R4	Gene names	VPS72, TCFL1, YL1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

ASPH_HUMAN
θ value	2.36792 (rank : 67)	NC score	0.029199 (rank : 116)
Query Neighborhood Hits	150	Target Neighborhood Hits	158	Shared Neighborhood Hits	5
SwissProt Accessions	Q12797	Gene names	ASPH
Domain Architecture
Description	Aspartyl/asparaginyl beta-hydroxylase (EC 1.14.11.16) (Aspartate beta- hydroxylase) (ASP beta-hydroxylase) (Peptide-aspartate beta- dioxygenase).

BSN_MOUSE
θ value	2.36792 (rank : 68)	NC score	0.049856 (rank : 83)
Query Neighborhood Hits	150	Target Neighborhood Hits	2057	Shared Neighborhood Hits	82
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CO002_HUMAN
θ value	2.36792 (rank : 69)	NC score	0.047177 (rank : 88)
Query Neighborhood Hits	150	Target Neighborhood Hits	387	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NZP6	Gene names	C15orf2
Domain Architecture	No domain graphic available
Description	Protein C15orf2.

ERRFI_HUMAN
θ value	2.36792 (rank : 70)	NC score	0.024799 (rank : 130)
Query Neighborhood Hits	150	Target Neighborhood Hits	72	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UJM3, Q9NTG9, Q9UD05	Gene names	ERRFI1, MIG6
Domain Architecture	No domain graphic available
Description	ERBB receptor feedback inhibitor 1 (Mitogen-inducible gene 6 protein) (Mig-6).

RASF8_MOUSE
θ value	2.36792 (rank : 71)	NC score	0.036024 (rank : 103)
Query Neighborhood Hits	150	Target Neighborhood Hits	391	Shared Neighborhood Hits	29
SwissProt Accessions	Q8CJ96, Q8CCW4, Q9CU91	Gene names	Rassf8
Domain Architecture	No domain graphic available
Description	Ras association domain-containing protein 8 (Carcinoma-associated protein HOJ-1 homolog).

ZF106_HUMAN
θ value	2.36792 (rank : 72)	NC score	0.024841 (rank : 129)
Query Neighborhood Hits	150	Target Neighborhood Hits	470	Shared Neighborhood Hits	17
SwissProt Accessions	Q9H2Y7, Q6NSD9, Q6PEK1, Q86T43, Q86T45, Q86T50, Q86T58, Q86TA9, Q96M37, Q9H7B8	Gene names	ZFP106, ZNF474
Domain Architecture	No domain graphic available
Description	Zinc finger protein 106 homolog (Zfp-106) (Zinc finger protein 474).

BTBD5_HUMAN
θ value	3.0926 (rank : 73)	NC score	0.005004 (rank : 192)
Query Neighborhood Hits	150	Target Neighborhood Hits	190	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NXS3	Gene names	BTBD5
Domain Architecture
Description	BTB/POZ domain-containing protein 5.

CTGE5_MOUSE
θ value	3.0926 (rank : 74)	NC score	0.024610 (rank : 132)
Query Neighborhood Hits	150	Target Neighborhood Hits	928	Shared Neighborhood Hits	45
SwissProt Accessions	Q8R311, Q8CIE3	Gene names	Ctage5, Mea6, Mgea6
Domain Architecture	No domain graphic available
Description	Cutaneous T-cell lymphoma-associated antigen 5 homolog (cTAGE-5 protein) (Meningioma-expressed antigen 6).

CUTL1_MOUSE
θ value	3.0926 (rank : 75)	NC score	0.028324 (rank : 119)
Query Neighborhood Hits	150	Target Neighborhood Hits	1620	Shared Neighborhood Hits	63
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

FLNB_HUMAN
θ value	3.0926 (rank : 76)	NC score	0.019329 (rank : 161)
Query Neighborhood Hits	150	Target Neighborhood Hits	111	Shared Neighborhood Hits	10
SwissProt Accessions	O75369, Q13706, Q8WXS9, Q8WXT0, Q8WXT1, Q8WXT2, Q9NRB5, Q9NT26, Q9UEV9	Gene names	FLNB, FLN1L, FLN3, TABP, TAP
Domain Architecture
Description	Filamin-B (FLN-B) (Beta-filamin) (Actin-binding-like protein) (Thyroid autoantigen) (Truncated actin-binding protein) (Truncated ABP) (ABP- 280 homolog) (ABP-278) (Filamin 3) (Filamin homolog 1) (Fh1).

MBB1A_HUMAN
θ value	3.0926 (rank : 77)	NC score	0.042364 (rank : 92)
Query Neighborhood Hits	150	Target Neighborhood Hits	665	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

MYH10_HUMAN
θ value	3.0926 (rank : 78)	NC score	0.020179 (rank : 155)
Query Neighborhood Hits	150	Target Neighborhood Hits	1620	Shared Neighborhood Hits	44
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH10_MOUSE
θ value	3.0926 (rank : 79)	NC score	0.020354 (rank : 153)
Query Neighborhood Hits	150	Target Neighborhood Hits	1612	Shared Neighborhood Hits	44
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

NACAM_MOUSE
θ value	3.0926 (rank : 80)	NC score	0.063697 (rank : 38)
Query Neighborhood Hits	150	Target Neighborhood Hits	1866	Shared Neighborhood Hits	67
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

NTNG1_HUMAN
θ value	3.0926 (rank : 81)	NC score	0.019120 (rank : 165)
Query Neighborhood Hits	150	Target Neighborhood Hits	247	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y2I2, Q5VU86, Q5VU87, Q5VU89, Q5VU90, Q5VU91, Q7Z2Y3, Q8N633	Gene names	NTNG1, KIAA0976, LMNT1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

PHAR3_MOUSE
θ value	3.0926 (rank : 82)	NC score	0.018792 (rank : 169)
Query Neighborhood Hits	150	Target Neighborhood Hits	206	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BYK5, Q8BYS8, Q8C058, Q9DB87	Gene names	Phactr3, Scapin1
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 3 (Scapinin) (Scaffold-associated PP1- inhibiting protein).

PKHA6_HUMAN
θ value	3.0926 (rank : 83)	NC score	0.023782 (rank : 140)
Query Neighborhood Hits	150	Target Neighborhood Hits	556	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

RECQ4_MOUSE
θ value	3.0926 (rank : 84)	NC score	0.012453 (rank : 184)
Query Neighborhood Hits	150	Target Neighborhood Hits	206	Shared Neighborhood Hits	8
SwissProt Accessions	Q75NR7, Q76MT1, Q99PV9	Gene names	Recql4, Recq4
Domain Architecture	No domain graphic available
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4).

SAPS1_HUMAN
θ value	3.0926 (rank : 85)	NC score	0.036500 (rank : 101)
Query Neighborhood Hits	150	Target Neighborhood Hits	704	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

CBP_MOUSE
θ value	4.03905 (rank : 86)	NC score	0.050161 (rank : 79)
Query Neighborhood Hits	150	Target Neighborhood Hits	1051	Shared Neighborhood Hits	49
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

DACT1_MOUSE
θ value	4.03905 (rank : 87)	NC score	0.018313 (rank : 171)
Query Neighborhood Hits	150	Target Neighborhood Hits	93	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R4A3, Q80VG9, Q8BP49, Q9JK89	Gene names	Dact1, Thyex3
Domain Architecture	No domain graphic available
Description	Dapper homolog 1 (MDpr1) (Frodo) (Thymus-expressed novel gene 3 protein).

GOGA4_MOUSE
θ value	4.03905 (rank : 88)	NC score	0.023792 (rank : 139)
Query Neighborhood Hits	150	Target Neighborhood Hits	1939	Shared Neighborhood Hits	52
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

HS74L_HUMAN
θ value	4.03905 (rank : 89)	NC score	0.014822 (rank : 176)
Query Neighborhood Hits	150	Target Neighborhood Hits	141	Shared Neighborhood Hits	15
SwissProt Accessions	O95757, Q4W5M5, Q8IWA2	Gene names	HSPA4L, APG1, OSP94
Domain Architecture
Description	Heat shock 70 kDa protein 4L (Osmotic stress protein 94) (Heat shock 70-related protein APG-1).

IASPP_HUMAN
θ value	4.03905 (rank : 90)	NC score	0.046385 (rank : 89)
Query Neighborhood Hits	150	Target Neighborhood Hits	688	Shared Neighborhood Hits	34
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

JAG1_MOUSE
θ value	4.03905 (rank : 91)	NC score	0.018906 (rank : 167)
Query Neighborhood Hits	150	Target Neighborhood Hits	518	Shared Neighborhood Hits	18
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

LEO1_MOUSE
θ value	4.03905 (rank : 92)	NC score	0.037256 (rank : 99)
Query Neighborhood Hits	150	Target Neighborhood Hits	946	Shared Neighborhood Hits	26
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

MNAB_MOUSE
θ value	4.03905 (rank : 93)	NC score	0.023508 (rank : 142)
Query Neighborhood Hits	150	Target Neighborhood Hits	231	Shared Neighborhood Hits	14
SwissProt Accessions	P0C090	Gene names	Mnab
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein.

MUC1_HUMAN
θ value	4.03905 (rank : 94)	NC score	0.038294 (rank : 98)
Query Neighborhood Hits	150	Target Neighborhood Hits	975	Shared Neighborhood Hits	42
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

OR2J3_HUMAN
θ value	4.03905 (rank : 95)	NC score	-0.000030 (rank : 197)
Query Neighborhood Hits	150	Target Neighborhood Hits	748	Shared Neighborhood Hits	4
SwissProt Accessions	O76001, Q96R15, Q9GZK5, Q9GZL4, Q9GZL5	Gene names	OR2J3
Domain Architecture
Description	Olfactory receptor 2J3 (Olfactory receptor 6-6) (OR6-6) (Hs6M1-3).

STAB2_MOUSE
θ value	4.03905 (rank : 96)	NC score	0.019232 (rank : 162)
Query Neighborhood Hits	150	Target Neighborhood Hits	528	Shared Neighborhood Hits	20
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

SUHW4_HUMAN
θ value	4.03905 (rank : 97)	NC score	0.003428 (rank : 195)
Query Neighborhood Hits	150	Target Neighborhood Hits	860	Shared Neighborhood Hits	12
SwissProt Accessions	Q6N043, Q6MZM6, Q6N085, Q9H0U5, Q9HCI8, Q9NXS0	Gene names	SUHW4, KIAA1584
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 4.

SYNE1_HUMAN
θ value	4.03905 (rank : 98)	NC score	0.026316 (rank : 123)
Query Neighborhood Hits	150	Target Neighborhood Hits	1484	Shared Neighborhood Hits	43
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

UBQL3_MOUSE
θ value	4.03905 (rank : 99)	NC score	0.012874 (rank : 183)
Query Neighborhood Hits	150	Target Neighborhood Hits	120	Shared Neighborhood Hits	7
SwissProt Accessions	Q8C5U9	Gene names	Ubqln3
Domain Architecture
Description	Ubiquilin-3.

UT14A_HUMAN
θ value	4.03905 (rank : 100)	NC score	0.021682 (rank : 148)
Query Neighborhood Hits	150	Target Neighborhood Hits	168	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BVJ6, Q5JYF1	Gene names	UTP14A
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 14 homolog A (Antigen NY-CO- 16).

WTAP_HUMAN
θ value	4.03905 (rank : 101)	NC score	0.033831 (rank : 104)
Query Neighborhood Hits	150	Target Neighborhood Hits	262	Shared Neighborhood Hits	21
SwissProt Accessions	Q15007, Q96T28, Q9BYJ7, Q9H4E2	Gene names	WTAP, KIAA0105
Domain Architecture	No domain graphic available
Description	Wilms' tumor 1-associating protein (WT1-associated protein) (Putative pre-mRNA-splicing regulator female-lethal(2D) homolog).

ZN638_HUMAN
θ value	4.03905 (rank : 102)	NC score	0.023999 (rank : 138)
Query Neighborhood Hits	150	Target Neighborhood Hits	343	Shared Neighborhood Hits	25
SwissProt Accessions	Q14966, Q53R34, Q5XJ05, Q68DP3, Q6P2H2, Q7Z3T7, Q8NF92, Q8TCA1, Q9H2G1, Q9NP37	Gene names	ZNF638, NP220, ZFML
Domain Architecture	No domain graphic available
Description	Zinc finger protein 638 (Nuclear protein 220) (Zinc-finger matrin-like protein) (Cutaneous T-cell lymphoma-associated antigen se33-1) (CTCL tumor antigen se33-1).

FIBA_HUMAN
θ value	5.27518 (rank : 103)	NC score	0.018927 (rank : 166)
Query Neighborhood Hits	150	Target Neighborhood Hits	132	Shared Neighborhood Hits	7
SwissProt Accessions	P02671, Q9BX62, Q9UCH2	Gene names	FGA
Domain Architecture
Description	Fibrinogen alpha chain precursor [Contains: Fibrinopeptide A].

JADE2_MOUSE
θ value	5.27518 (rank : 104)	NC score	0.040610 (rank : 95)
Query Neighborhood Hits	150	Target Neighborhood Hits	560	Shared Neighborhood Hits	31
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

JHD2B_HUMAN
θ value	5.27518 (rank : 105)	NC score	0.013580 (rank : 182)
Query Neighborhood Hits	150	Target Neighborhood Hits	171	Shared Neighborhood Hits	11
SwissProt Accessions	Q7LBC6, Q9BVH6, Q9BW93, Q9BZ52, Q9NYF4, Q9UPS0	Gene names	JMJD1B, C5orf7, JHDM2B, KIAA1082
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2B (EC 1.14.11.-) (Jumonji domain-containing protein 1B) (Nuclear protein 5qNCA).

MCPH1_MOUSE
θ value	5.27518 (rank : 106)	NC score	0.019218 (rank : 163)
Query Neighborhood Hits	150	Target Neighborhood Hits	116	Shared Neighborhood Hits	5
SwissProt Accessions	Q7TT79, Q8BNI9, Q8C9I7	Gene names	Mcph1
Domain Architecture
Description	Microcephalin.

MYH11_MOUSE
θ value	5.27518 (rank : 107)	NC score	0.019124 (rank : 164)
Query Neighborhood Hits	150	Target Neighborhood Hits	1777	Shared Neighborhood Hits	45
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

NID1_MOUSE
θ value	5.27518 (rank : 108)	NC score	0.014585 (rank : 178)
Query Neighborhood Hits	150	Target Neighborhood Hits	335	Shared Neighborhood Hits	13
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

SENP2_MOUSE
θ value	5.27518 (rank : 109)	NC score	0.011588 (rank : 185)
Query Neighborhood Hits	150	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	Q91ZX6, Q544T8, Q9D4Z0	Gene names	Senp2, Smt3ip2
Domain Architecture
Description	Sentrin-specific protease 2 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP2) (SUMO-1/Smt3-specific isopeptidase 2) (Smt3ip2) (Axam2).

SMC4_HUMAN
θ value	5.27518 (rank : 110)	NC score	0.019422 (rank : 160)
Query Neighborhood Hits	150	Target Neighborhood Hits	937	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NTJ3, O95752, Q8NDL4, Q9UNT9	Gene names	SMC4L1, CAPC, SMC4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (hCAP-C) (XCAP-C homolog).

SSH3_HUMAN
θ value	5.27518 (rank : 111)	NC score	0.014305 (rank : 180)
Query Neighborhood Hits	150	Target Neighborhood Hits	75	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TE77, Q6PK42, Q76I75, Q8N9L8, Q8WYL0, Q9NV45, Q9NWZ7	Gene names	SSH3, SSH3L
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 3 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-3L) (hSSH-3L).

TCGAP_MOUSE
θ value	5.27518 (rank : 112)	NC score	0.017337 (rank : 174)
Query Neighborhood Hits	150	Target Neighborhood Hits	409	Shared Neighborhood Hits	26
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

TRIPB_HUMAN
θ value	5.27518 (rank : 113)	NC score	0.024373 (rank : 134)
Query Neighborhood Hits	150	Target Neighborhood Hits	1587	Shared Neighborhood Hits	50
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

UTRO_HUMAN
θ value	5.27518 (rank : 114)	NC score	0.022674 (rank : 145)
Query Neighborhood Hits	150	Target Neighborhood Hits	960	Shared Neighborhood Hits	40
SwissProt Accessions	P46939	Gene names	UTRN, DMDL
Domain Architecture
Description	Utrophin (Dystrophin-related protein 1) (DRP1) (DRP).

ANR11_HUMAN
θ value	6.88961 (rank : 115)	NC score	0.053204 (rank : 65)
Query Neighborhood Hits	150	Target Neighborhood Hits	1289	Shared Neighborhood Hits	58
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

APBA2_MOUSE
θ value	6.88961 (rank : 116)	NC score	0.006988 (rank : 190)
Query Neighborhood Hits	150	Target Neighborhood Hits	219	Shared Neighborhood Hits	4
SwissProt Accessions	P98084, Q6PAJ2	Gene names	Apba2, X11l
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

BPA1_MOUSE
θ value	6.88961 (rank : 117)	NC score	0.024703 (rank : 131)
Query Neighborhood Hits	150	Target Neighborhood Hits	1477	Shared Neighborhood Hits	41
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

BTBD5_MOUSE
θ value	6.88961 (rank : 118)	NC score	0.003927 (rank : 194)
Query Neighborhood Hits	150	Target Neighborhood Hits	189	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CR40, Q9CYV0	Gene names	Btbd5
Domain Architecture
Description	BTB/POZ domain-containing protein 5.

CBP_HUMAN
θ value	6.88961 (rank : 119)	NC score	0.042224 (rank : 93)
Query Neighborhood Hits	150	Target Neighborhood Hits	941	Shared Neighborhood Hits	43
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

DIAP1_HUMAN
θ value	6.88961 (rank : 120)	NC score	0.029983 (rank : 114)
Query Neighborhood Hits	150	Target Neighborhood Hits	784	Shared Neighborhood Hits	55
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

EFS_MOUSE
θ value	6.88961 (rank : 121)	NC score	0.022847 (rank : 144)
Query Neighborhood Hits	150	Target Neighborhood Hits	389	Shared Neighborhood Hits	25
SwissProt Accessions	Q64355	Gene names	Efs, Sin
Domain Architecture
Description	Embryonal Fyn-associated substrate (SRC-interacting protein) (Signal- integrating protein).

ITSN2_MOUSE
θ value	6.88961 (rank : 122)	NC score	0.010097 (rank : 187)
Query Neighborhood Hits	150	Target Neighborhood Hits	1371	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

JAG1_HUMAN
θ value	6.88961 (rank : 123)	NC score	0.017399 (rank : 173)
Query Neighborhood Hits	150	Target Neighborhood Hits	514	Shared Neighborhood Hits	17
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

K1802_HUMAN
θ value	6.88961 (rank : 124)	NC score	0.036044 (rank : 102)
Query Neighborhood Hits	150	Target Neighborhood Hits	1378	Shared Neighborhood Hits	46
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

MAVS_MOUSE
θ value	6.88961 (rank : 125)	NC score	0.020083 (rank : 157)
Query Neighborhood Hits	150	Target Neighborhood Hits	170	Shared Neighborhood Hits	10
SwissProt Accessions	Q8VCF0	Gene names	Mavs, Ips1, Visa
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif).

MKL1_MOUSE
θ value	6.88961 (rank : 126)	NC score	0.036988 (rank : 100)
Query Neighborhood Hits	150	Target Neighborhood Hits	667	Shared Neighborhood Hits	33
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

MYH11_HUMAN
θ value	6.88961 (rank : 127)	NC score	0.020107 (rank : 156)
Query Neighborhood Hits	150	Target Neighborhood Hits	1806	Shared Neighborhood Hits	51
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

PDZD8_HUMAN
θ value	6.88961 (rank : 128)	NC score	0.018709 (rank : 170)
Query Neighborhood Hits	150	Target Neighborhood Hits	185	Shared Neighborhood Hits	14
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

RPGR_HUMAN
θ value	6.88961 (rank : 129)	NC score	0.010085 (rank : 188)
Query Neighborhood Hits	150	Target Neighborhood Hits	279	Shared Neighborhood Hits	13
SwissProt Accessions	Q92834, O00702, O00737, Q8N5T6, Q93039, Q9HD29, Q9UMR1	Gene names	RPGR, RP3, XLRP3
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator.

RUFY2_HUMAN
θ value	6.88961 (rank : 130)	NC score	0.020463 (rank : 152)
Query Neighborhood Hits	150	Target Neighborhood Hits	1208	Shared Neighborhood Hits	42
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

RYBP_HUMAN
θ value	6.88961 (rank : 131)	NC score	0.019916 (rank : 158)
Query Neighborhood Hits	150	Target Neighborhood Hits	50	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N488, Q9P2W5, Q9UMW4	Gene names	RYBP, DEDAF, YEAF1
Domain Architecture	No domain graphic available
Description	RING1 and YY1-binding protein (Death effector domain-associated factor) (DED-associated factor) (YY1 and E4TF1-associated factor 1) (Apoptin-associating protein 1) (APAP-1).

SOX30_MOUSE
θ value	6.88961 (rank : 132)	NC score	0.031329 (rank : 111)
Query Neighborhood Hits	150	Target Neighborhood Hits	374	Shared Neighborhood Hits	31
SwissProt Accessions	Q8CGW4	Gene names	Sox30
Domain Architecture
Description	Transcription factor SOX-30.

SSH1_HUMAN
θ value	6.88961 (rank : 133)	NC score	0.011167 (rank : 186)
Query Neighborhood Hits	150	Target Neighborhood Hits	164	Shared Neighborhood Hits	14
SwissProt Accessions	Q8WYL5, Q6P6C0, Q8N9A7, Q8WYL3, Q8WYL4, Q9P2P8	Gene names	SSH1, KIAA1298, SSH1L
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 1 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-1L) (hSSH-1L).

SYNE2_HUMAN
θ value	6.88961 (rank : 134)	NC score	0.027013 (rank : 121)
Query Neighborhood Hits	150	Target Neighborhood Hits	1323	Shared Neighborhood Hits	42
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

TMPS2_HUMAN
θ value	6.88961 (rank : 135)	NC score	0.004655 (rank : 193)
Query Neighborhood Hits	150	Target Neighborhood Hits	252	Shared Neighborhood Hits	6
SwissProt Accessions	O15393, Q9BXX1	Gene names	TMPRSS2, PRSS10
Domain Architecture
Description	Transmembrane protease, serine 2 precursor (EC 3.4.21.-) [Contains: Transmembrane protease, serine 2 non-catalytic chain; Transmembrane protease, serine 2 catalytic chain].

AZI1_HUMAN
θ value	8.99809 (rank : 136)	NC score	0.021382 (rank : 149)
Query Neighborhood Hits	150	Target Neighborhood Hits	1000	Shared Neighborhood Hits	41
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

CO020_HUMAN
θ value	8.99809 (rank : 137)	NC score	0.024408 (rank : 133)
Query Neighborhood Hits	150	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H611	Gene names	C15orf20
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf20.

CT2NL_HUMAN
θ value	8.99809 (rank : 138)	NC score	0.031618 (rank : 110)
Query Neighborhood Hits	150	Target Neighborhood Hits	1059	Shared Neighborhood Hits	49
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

HMMR_HUMAN
θ value	8.99809 (rank : 139)	NC score	0.017622 (rank : 172)
Query Neighborhood Hits	150	Target Neighborhood Hits	1082	Shared Neighborhood Hits	34
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

LAMC2_MOUSE
θ value	8.99809 (rank : 140)	NC score	0.013861 (rank : 181)
Query Neighborhood Hits	150	Target Neighborhood Hits	614	Shared Neighborhood Hits	30
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

LPP_HUMAN
θ value	8.99809 (rank : 141)	NC score	0.023658 (rank : 141)
Query Neighborhood Hits	150	Target Neighborhood Hits	775	Shared Neighborhood Hits	35
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

MY18A_MOUSE
θ value	8.99809 (rank : 142)	NC score	0.019449 (rank : 159)
Query Neighborhood Hits	150	Target Neighborhood Hits	1989	Shared Neighborhood Hits	49
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

NFRKB_MOUSE
θ value	8.99809 (rank : 143)	NC score	0.025811 (rank : 125)
Query Neighborhood Hits	150	Target Neighborhood Hits	393	Shared Neighborhood Hits	25
SwissProt Accessions	Q6PIJ4, Q8BWV5, Q8K0X6	Gene names	Nfrkb
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

NTNG1_MOUSE
θ value	8.99809 (rank : 144)	NC score	0.014675 (rank : 177)
Query Neighborhood Hits	150	Target Neighborhood Hits	246	Shared Neighborhood Hits	14
SwissProt Accessions	Q8R4G0, Q68FE5, Q69ZU3, Q8R4F3, Q8R4F4, Q8R4F5, Q8R4F6, Q8R4F7, Q8R4F8, Q8R4F9, Q9ESR3, Q9ESR4, Q9ESR5, Q9ESR6, Q9ESR7, Q9ESR8	Gene names	Ntng1, Kiaa0976, Lmnt1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

RTP3_MOUSE
θ value	8.99809 (rank : 145)	NC score	0.049385 (rank : 84)
Query Neighborhood Hits	150	Target Neighborhood Hits	374	Shared Neighborhood Hits	32
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

RYBP_MOUSE
θ value	8.99809 (rank : 146)	NC score	0.016441 (rank : 175)
Query Neighborhood Hits	150	Target Neighborhood Hits	39	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CCI5, Q9WVK2	Gene names	Rybp, Dedaf
Domain Architecture	No domain graphic available
Description	RING1 and YY1-binding protein (Death effector domain-associated factor) (DED-associated factor).

SMCE1_MOUSE
θ value	8.99809 (rank : 147)	NC score	0.024213 (rank : 136)
Query Neighborhood Hits	150	Target Neighborhood Hits	409	Shared Neighborhood Hits	25
SwissProt Accessions	O54941, Q8BPD9	Gene names	Smarce1, Baf57
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator chromatin subfamily E member 1 (BRG1-associated factor 57).

SRBP1_MOUSE
θ value	8.99809 (rank : 148)	NC score	0.022894 (rank : 143)
Query Neighborhood Hits	150	Target Neighborhood Hits	384	Shared Neighborhood Hits	25
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

TRI62_HUMAN
θ value	8.99809 (rank : 149)	NC score	0.006286 (rank : 191)
Query Neighborhood Hits	150	Target Neighborhood Hits	584	Shared Neighborhood Hits	29
SwissProt Accessions	Q9BVG3, Q9NVG0	Gene names	TRIM62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

UTX_HUMAN
θ value	8.99809 (rank : 150)	NC score	0.009578 (rank : 189)
Query Neighborhood Hits	150	Target Neighborhood Hits	161	Shared Neighborhood Hits	6
SwissProt Accessions	O15550	Gene names	UTX
Domain Architecture
Description	Ubiquitously transcribed X chromosome tetratricopeptide repeat protein (Ubiquitously transcribed TPR protein on the X chromosome).

ANKR6_HUMAN
θ value	θ > 10 (rank : 151)	NC score	0.050012 (rank : 82)
Query Neighborhood Hits	150	Target Neighborhood Hits	439	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y2G4, Q9NU24, Q9UFQ9	Gene names	ANKRD6, KIAA0957
Domain Architecture
Description	Ankyrin repeat domain-containing protein 6.

ANR22_HUMAN
θ value	θ > 10 (rank : 152)	NC score	0.054035 (rank : 62)
Query Neighborhood Hits	150	Target Neighborhood Hits	243	Shared Neighborhood Hits	7
SwissProt Accessions	Q5VYY1, Q8WU06	Gene names	ANKRD22
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 22.

ANR49_MOUSE
θ value	θ > 10 (rank : 153)	NC score	0.050091 (rank : 81)
Query Neighborhood Hits	150	Target Neighborhood Hits	285	Shared Neighborhood Hits	7
SwissProt Accessions	Q8VE42, Q9Z2S1	Gene names	Ankrd49, Fgif, Gbif
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor) (Fetal globin-increasing factor).

BASP_HUMAN
θ value	θ > 10 (rank : 154)	NC score	0.053760 (rank : 63)
Query Neighborhood Hits	150	Target Neighborhood Hits	321	Shared Neighborhood Hits	27
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

CBX1_HUMAN
θ value	θ > 10 (rank : 155)	NC score	0.062384 (rank : 43)
Query Neighborhood Hits	150	Target Neighborhood Hits	44	Shared Neighborhood Hits	5
SwissProt Accessions	P83916, P23197	Gene names	CBX1, CBX
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25) (HP1Hsbeta) (p25beta).

CBX1_MOUSE
θ value	θ > 10 (rank : 156)	NC score	0.062384 (rank : 44)
Query Neighborhood Hits	150	Target Neighborhood Hits	44	Shared Neighborhood Hits	5
SwissProt Accessions	P83917, P23197	Gene names	Cbx1, Cbx
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25).

CBX3_HUMAN
θ value	θ > 10 (rank : 157)	NC score	0.063829 (rank : 37)
Query Neighborhood Hits	150	Target Neighborhood Hits	36	Shared Neighborhood Hits	4
SwissProt Accessions	Q13185, Q96CD7, Q99409, Q9BVS3, Q9P0Z6	Gene names	CBX3
Domain Architecture
Description	Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein) (HECH).

CBX3_MOUSE
θ value	θ > 10 (rank : 158)	NC score	0.064469 (rank : 35)
Query Neighborhood Hits	150	Target Neighborhood Hits	39	Shared Neighborhood Hits	4
SwissProt Accessions	P23198, Q921C4	Gene names	Cbx3
Domain Architecture
Description	Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein) (M32).

CBX5_HUMAN
θ value	θ > 10 (rank : 159)	NC score	0.059348 (rank : 50)
Query Neighborhood Hits	150	Target Neighborhood Hits	70	Shared Neighborhood Hits	5
SwissProt Accessions	P45973	Gene names	CBX5, HP1A
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha) (Antigen p25).

CBX5_MOUSE
θ value	θ > 10 (rank : 160)	NC score	0.058901 (rank : 52)
Query Neighborhood Hits	150	Target Neighborhood Hits	67	Shared Neighborhood Hits	5
SwissProt Accessions	Q61686, Q9CS35, Q9CXD1	Gene names	Cbx5, Hp1a
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha).

CSKI1_HUMAN
θ value	θ > 10 (rank : 161)	NC score	0.050500 (rank : 76)
Query Neighborhood Hits	150	Target Neighborhood Hits	997	Shared Neighborhood Hits	44
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

CTTB2_HUMAN
θ value	θ > 10 (rank : 162)	NC score	0.050105 (rank : 80)
Query Neighborhood Hits	150	Target Neighborhood Hits	1061	Shared Neighborhood Hits	50
SwissProt Accessions	Q8WZ74, O43389, Q7LG11, Q9C0A5	Gene names	CTTNBP2, C7orf8, CORTBP2, KIAA1758
Domain Architecture	No domain graphic available
Description	Cortactin-binding protein 2 (CortBP2).

DPF1_HUMAN
θ value	θ > 10 (rank : 163)	NC score	0.055271 (rank : 59)
Query Neighborhood Hits	150	Target Neighborhood Hits	136	Shared Neighborhood Hits	9
SwissProt Accessions	Q92782	Gene names	DPF1, NEUD4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

GSCR1_HUMAN
θ value	θ > 10 (rank : 164)	NC score	0.053201 (rank : 66)
Query Neighborhood Hits	150	Target Neighborhood Hits	674	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

INVS_MOUSE
θ value	θ > 10 (rank : 165)	NC score	0.050462 (rank : 77)
Query Neighborhood Hits	150	Target Neighborhood Hits	609	Shared Neighborhood Hits	24
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

LAD1_MOUSE
θ value	θ > 10 (rank : 166)	NC score	0.052393 (rank : 69)
Query Neighborhood Hits	150	Target Neighborhood Hits	391	Shared Neighborhood Hits	25
SwissProt Accessions	P57016	Gene names	Lad1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (Linear IgA disease autoantigen).

MARCS_HUMAN
θ value	θ > 10 (rank : 167)	NC score	0.050509 (rank : 75)
Query Neighborhood Hits	150	Target Neighborhood Hits	204	Shared Neighborhood Hits	19
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

MDC1_HUMAN
θ value	θ > 10 (rank : 168)	NC score	0.059806 (rank : 48)
Query Neighborhood Hits	150	Target Neighborhood Hits	1446	Shared Neighborhood Hits	56
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

MDC1_MOUSE
θ value	θ > 10 (rank : 169)	NC score	0.065955 (rank : 33)
Query Neighborhood Hits	150	Target Neighborhood Hits	998	Shared Neighborhood Hits	49
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

MPP8_HUMAN
θ value	θ > 10 (rank : 170)	NC score	0.066082 (rank : 32)
Query Neighborhood Hits	150	Target Neighborhood Hits	948	Shared Neighborhood Hits	39
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

MYST3_HUMAN
θ value	θ > 10 (rank : 171)	NC score	0.051796 (rank : 71)
Query Neighborhood Hits	150	Target Neighborhood Hits	772	Shared Neighborhood Hits	47
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

MYST4_HUMAN
θ value	θ > 10 (rank : 172)	NC score	0.052489 (rank : 68)
Query Neighborhood Hits	150	Target Neighborhood Hits	671	Shared Neighborhood Hits	45
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

PHF10_HUMAN
θ value	θ > 10 (rank : 173)	NC score	0.064442 (rank : 36)
Query Neighborhood Hits	150	Target Neighborhood Hits	151	Shared Neighborhood Hits	13
SwissProt Accessions	Q8WUB8, Q2YDA3, Q9BXD2, Q9NV26	Gene names	PHF10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10 (XAP135).

PHF10_MOUSE
θ value	θ > 10 (rank : 174)	NC score	0.062466 (rank : 42)
Query Neighborhood Hits	150	Target Neighborhood Hits	131	Shared Neighborhood Hits	10
SwissProt Accessions	Q9D8M7, Q99LV5	Gene names	Phf10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10.

PHF11_HUMAN
θ value	θ > 10 (rank : 175)	NC score	0.085380 (rank : 26)
Query Neighborhood Hits	150	Target Neighborhood Hits	42	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UIL8, Q9Y5A2	Gene names	PHF11, BCAP
Domain Architecture	No domain graphic available
Description	PHD finger protein 11 (BRCA1 C-terminus-associated protein) (NY-REN-34 antigen).

PHF6_HUMAN
θ value	θ > 10 (rank : 176)	NC score	0.065293 (rank : 34)
Query Neighborhood Hits	150	Target Neighborhood Hits	37	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IWS0, Q96JK3, Q9BRU0	Gene names	PHF6, KIAA1823
Domain Architecture	No domain graphic available
Description	PHD finger protein 6 (PHD-like zinc finger protein).

PHF6_MOUSE
θ value	θ > 10 (rank : 177)	NC score	0.063163 (rank : 40)
Query Neighborhood Hits	150	Target Neighborhood Hits	39	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D4J7, Q80T86, Q8BYT8, Q8C1B5	Gene names	Phf6, Kiaa1823
Domain Architecture	No domain graphic available
Description	PHD finger protein 6.

PHF7_HUMAN
θ value	θ > 10 (rank : 178)	NC score	0.051629 (rank : 72)
Query Neighborhood Hits	150	Target Neighborhood Hits	71	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BWX1	Gene names	PHF7
Domain Architecture	No domain graphic available
Description	PHD finger protein 7 (Testis development protein NYD-SP6).

PRP1_HUMAN
θ value	θ > 10 (rank : 179)	NC score	0.056982 (rank : 55)
Query Neighborhood Hits	150	Target Neighborhood Hits	385	Shared Neighborhood Hits	33
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

PRP2_MOUSE
θ value	θ > 10 (rank : 180)	NC score	0.059378 (rank : 49)
Query Neighborhood Hits	150	Target Neighborhood Hits	347	Shared Neighborhood Hits	33
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

PRR12_HUMAN
θ value	θ > 10 (rank : 181)	NC score	0.051900 (rank : 70)
Query Neighborhood Hits	150	Target Neighborhood Hits	460	Shared Neighborhood Hits	42
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

RAI1_HUMAN
θ value	θ > 10 (rank : 182)	NC score	0.061269 (rank : 45)
Query Neighborhood Hits	150	Target Neighborhood Hits	360	Shared Neighborhood Hits	18
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

RAI1_MOUSE
θ value	θ > 10 (rank : 183)	NC score	0.068838 (rank : 30)
Query Neighborhood Hits	150	Target Neighborhood Hits	344	Shared Neighborhood Hits	25
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

RSF1_HUMAN
θ value	θ > 10 (rank : 184)	NC score	0.050432 (rank : 78)
Query Neighborhood Hits	150	Target Neighborhood Hits	539	Shared Neighborhood Hits	34
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

SETD7_HUMAN
θ value	θ > 10 (rank : 185)	NC score	0.060133 (rank : 47)
Query Neighborhood Hits	150	Target Neighborhood Hits	37	Shared Neighborhood Hits	13
SwissProt Accessions	Q8WTS6, Q9C0E6	Gene names	SETD7, KIAA1717, SET7
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET7 (EC 2.1.1.43) (Histone H3-K4 methyltransferase) (H3-K4-HMTase) (SET domain-containing protein 7) (Set9) (SET7/9).

SETD7_MOUSE
θ value	θ > 10 (rank : 186)	NC score	0.061225 (rank : 46)
Query Neighborhood Hits	150	Target Neighborhood Hits	39	Shared Neighborhood Hits	13
SwissProt Accessions	Q8VHL1	Gene names	Setd7, Set7
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET7 (EC 2.1.1.43) (Histone H3-K4 methyltransferase) (H3-K4-HMTase) (SET domain-containing protein 7).

SETD8_HUMAN
θ value	θ > 10 (rank : 187)	NC score	0.312043 (rank : 25)
Query Neighborhood Hits	150	Target Neighborhood Hits	114	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NQR1, Q86W83, Q8TD09	Gene names	SETD8, PRSET7, SET07, SET8
Domain Architecture
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8) (PR/SET domain-containing protein 07) (PR/SET07) (PR-Set7).

SETD8_MOUSE
θ value	θ > 10 (rank : 188)	NC score	0.313260 (rank : 24)
Query Neighborhood Hits	150	Target Neighborhood Hits	131	Shared Neighborhood Hits	26
SwissProt Accessions	Q2YDW7, Q8C0J9	Gene names	SETD8
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8).

SHAN1_HUMAN
θ value	θ > 10 (rank : 189)	NC score	0.055285 (rank : 58)
Query Neighborhood Hits	150	Target Neighborhood Hits	1041	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

SRRM1_HUMAN
θ value	θ > 10 (rank : 190)	NC score	0.054675 (rank : 61)
Query Neighborhood Hits	150	Target Neighborhood Hits	690	Shared Neighborhood Hits	45
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

SRRM1_MOUSE
θ value	θ > 10 (rank : 191)	NC score	0.059074 (rank : 51)
Query Neighborhood Hits	150	Target Neighborhood Hits	966	Shared Neighborhood Hits	56
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

TCF20_HUMAN
θ value	θ > 10 (rank : 192)	NC score	0.063062 (rank : 41)
Query Neighborhood Hits	150	Target Neighborhood Hits	323	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

TCF20_MOUSE
θ value	θ > 10 (rank : 193)	NC score	0.057375 (rank : 53)
Query Neighborhood Hits	150	Target Neighborhood Hits	396	Shared Neighborhood Hits	22
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

TXND2_HUMAN
θ value	θ > 10 (rank : 194)	NC score	0.051148 (rank : 74)
Query Neighborhood Hits	150	Target Neighborhood Hits	793	Shared Neighborhood Hits	38
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

WASIP_HUMAN
θ value	θ > 10 (rank : 195)	NC score	0.052956 (rank : 67)
Query Neighborhood Hits	150	Target Neighborhood Hits	458	Shared Neighborhood Hits	33
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

WASIP_MOUSE
θ value	θ > 10 (rank : 196)	NC score	0.056687 (rank : 56)
Query Neighborhood Hits	150	Target Neighborhood Hits	392	Shared Neighborhood Hits	33
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

WIRE_HUMAN
θ value	θ > 10 (rank : 197)	NC score	0.051215 (rank : 73)
Query Neighborhood Hits	150	Target Neighborhood Hits	329	Shared Neighborhood Hits	32
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

Hits sorted by NC score

SETB1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	150	Target Neighborhood Hits	150	Shared Neighborhood Hits	150
SwissProt Accessions	O88974, Q922K1	Gene names	Setdb1, Eset
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

SETB1_HUMAN
NC score	0.977838 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	150	Target Neighborhood Hits	141	Shared Neighborhood Hits	62
SwissProt Accessions	Q15047, Q96GM9	Gene names	SETDB1, KIAA0067
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

SETB2_HUMAN
NC score	0.857298 (rank : 3)	θ value	3.35642e-63 (rank : 3)
Query Neighborhood Hits	150	Target Neighborhood Hits	62	Shared Neighborhood Hits	26
SwissProt Accessions	Q96T68, Q86UD6, Q96AI6	Gene names	SETDB2, CLLD8
Domain Architecture
Description	Probable histone-lysine N-methyltransferase, H3 lysine-9 specific (EC 2.1.1.43) (Histone H3-K9 methyltransferase) (H3-K9-HMTase) (SET domain bifurcated 2) (Chronic lymphocytic leukemia deletion region gene 8 protein).

SUV91_HUMAN
NC score	0.654981 (rank : 4)	θ value	1.2077e-20 (rank : 7)
Query Neighborhood Hits	150	Target Neighborhood Hits	63	Shared Neighborhood Hits	23
SwissProt Accessions	O43463, Q53G60, Q6FHK6	Gene names	SUV39H1, SUV39H
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 1 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1).

SUV91_MOUSE
NC score	0.646271 (rank : 5)	θ value	5.99374e-20 (rank : 8)
Query Neighborhood Hits	150	Target Neighborhood Hits	69	Shared Neighborhood Hits	23
SwissProt Accessions	O54864, Q9JLC7, Q9JLP8	Gene names	Suv39h1, Suv39h
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 1 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 1) (H3-K9-HMTase 1) (Suppressor of variegation 3-9 homolog 1) (Su(var)3-9 homolog 1) (Position-effect variegation 3-9 homolog).

SUV92_MOUSE
NC score	0.628047 (rank : 6)	θ value	2.35696e-16 (rank : 9)
Query Neighborhood Hits	150	Target Neighborhood Hits	59	Shared Neighborhood Hits	23
SwissProt Accessions	Q9EQQ0, Q9CUK3, Q9JLP7	Gene names	Suv39h2
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2).

SUV92_HUMAN
NC score	0.627124 (rank : 7)	θ value	3.40345e-15 (rank : 10)
Query Neighborhood Hits	150	Target Neighborhood Hits	54	Shared Neighborhood Hits	23
SwissProt Accessions	Q9H5I1	Gene names	SUV39H2
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 2 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2).

SETD2_HUMAN
NC score	0.520230 (rank : 8)	θ value	1.9326e-10 (rank : 12)
Query Neighborhood Hits	150	Target Neighborhood Hits	412	Shared Neighborhood Hits	43
SwissProt Accessions	Q9BYW2, O75397, O75405, Q17RW8, Q5BKS9, Q5QGN2, Q69YI5, Q6IN64, Q6ZN53, Q6ZS25, Q8N3R0, Q8TCN0, Q9C0D1, Q9H696, Q9NZW9	Gene names	SETD2, HIF1, HYPB, KIAA1732, SET2
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36-specific (EC 2.1.1.43) (SET domain-containing protein 2) (hSET2) (Huntingtin- interacting protein HYPB) (Huntingtin-interacting protein 1) (HIF-1) (p231HBP).

EZH1_HUMAN
NC score	0.474638 (rank : 9)	θ value	1.29631e-06 (rank : 20)
Query Neighborhood Hits	150	Target Neighborhood Hits	121	Shared Neighborhood Hits	27
SwissProt Accessions	Q92800, O43287, Q14459	Gene names	EZH1, KIAA0388
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

EZH1_MOUSE
NC score	0.474207 (rank : 10)	θ value	1.29631e-06 (rank : 21)
Query Neighborhood Hits	150	Target Neighborhood Hits	126	Shared Neighborhood Hits	27
SwissProt Accessions	P70351, Q9R089	Gene names	Ezh1, Enx2
Domain Architecture
Description	Enhancer of zeste homolog 1 (ENX-2).

EZH2_HUMAN
NC score	0.469258 (rank : 11)	θ value	6.43352e-06 (rank : 22)
Query Neighborhood Hits	150	Target Neighborhood Hits	84	Shared Neighborhood Hits	26
SwissProt Accessions	Q15910, Q15755, Q92857	Gene names	EZH2
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

SET1A_HUMAN
NC score	0.464990 (rank : 12)	θ value	1.99992e-07 (rank : 19)
Query Neighborhood Hits	150	Target Neighborhood Hits	690	Shared Neighborhood Hits	63
SwissProt Accessions	O15047, Q6PIF3, Q8TAJ6	Gene names	SETD1A, KIAA0339, SET1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET1 (EC 2.1.1.43) (Set1/Ash2 histone methyltransferase complex subunit SET1) (SET-domain-containing protein 1A).

EZH2_MOUSE
NC score	0.461803 (rank : 13)	θ value	3.19293e-05 (rank : 23)
Query Neighborhood Hits	150	Target Neighborhood Hits	86	Shared Neighborhood Hits	26
SwissProt Accessions	Q61188, Q9R090	Gene names	Ezh2, Enx1h
Domain Architecture
Description	Enhancer of zeste homolog 2 (ENX-1).

MLL4_HUMAN
NC score	0.436026 (rank : 14)	θ value	3.89403e-11 (rank : 11)
Query Neighborhood Hits	150	Target Neighborhood Hits	722	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UMN6, O15022, O95836, Q96GP2, Q96IP3, Q9UK25, Q9Y668, Q9Y669	Gene names	MLL4, HRX2, KIAA0304, MLL2, TRX2
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 4 (Trithorax homolog 2).

HRX_HUMAN
NC score	0.429521 (rank : 15)	θ value	9.59137e-10 (rank : 13)
Query Neighborhood Hits	150	Target Neighborhood Hits	825	Shared Neighborhood Hits	59
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

NSD1_HUMAN
NC score	0.429519 (rank : 16)	θ value	3.08544e-08 (rank : 16)
Query Neighborhood Hits	150	Target Neighborhood Hits	427	Shared Neighborhood Hits	45
SwissProt Accessions	Q96L73, Q96PD8, Q96RN7	Gene names	NSD1, ARA267
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein) (Androgen receptor-associated coregulator 267).

NSD1_MOUSE
NC score	0.427981 (rank : 17)	θ value	3.08544e-08 (rank : 17)
Query Neighborhood Hits	150	Target Neighborhood Hits	472	Shared Neighborhood Hits	46
SwissProt Accessions	O88491, Q8C480, Q9CT70	Gene names	Nsd1
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific (EC 2.1.1.43) (H3-K36-HMTase) (H4-K20-HMTase) (Nuclear receptor-binding SET domain-containing protein 1) (NR-binding SET domain-containing protein).

EHMT2_HUMAN
NC score	0.361204 (rank : 18)	θ value	1.05554e-24 (rank : 4)
Query Neighborhood Hits	150	Target Neighborhood Hits	498	Shared Neighborhood Hits	33
SwissProt Accessions	Q96KQ7, Q14349, Q6PK06, Q96MH5, Q96QD0, Q9UQL8, Q9Y331	Gene names	EHMT2, BAT8, G9A, NG36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

EHMT2_MOUSE
NC score	0.359751 (rank : 19)	θ value	4.01107e-24 (rank : 5)
Query Neighborhood Hits	150	Target Neighborhood Hits	750	Shared Neighborhood Hits	47
SwissProt Accessions	Q9Z148, Q6PE08, Q8K4R6, Q8K4R7, Q9Z149	Gene names	Ehmt2, Bat8, G9a, Ng36
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Protein G9a).

EHMT1_HUMAN
NC score	0.352339 (rank : 20)	θ value	1.16704e-23 (rank : 6)
Query Neighborhood Hits	150	Target Neighborhood Hits	417	Shared Neighborhood Hits	31
SwissProt Accessions	Q9H9B1, Q8TCN7, Q96F53, Q96JF1, Q96KH4	Gene names	EHMT1, EUHMTASE1, KIAA1876
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 5) (H3-K9-HMTase 5) (Euchromatic histone-lysine N-methyltransferase 1) (Eu-HMTase1) (G9a- like protein 1) (GLP1).

MLL2_HUMAN
NC score	0.342439 (rank : 21)	θ value	1.63604e-09 (rank : 14)
Query Neighborhood Hits	150	Target Neighborhood Hits	1788	Shared Neighborhood Hits	87
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MLL3_MOUSE
NC score	0.328323 (rank : 22)	θ value	6.87365e-08 (rank : 18)
Query Neighborhood Hits	150	Target Neighborhood Hits	1399	Shared Neighborhood Hits	71
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

MLL3_HUMAN
NC score	0.315423 (rank : 23)	θ value	3.08544e-08 (rank : 15)
Query Neighborhood Hits	150	Target Neighborhood Hits	1644	Shared Neighborhood Hits	70
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

SETD8_MOUSE
NC score	0.313260 (rank : 24)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	150	Target Neighborhood Hits	131	Shared Neighborhood Hits	26
SwissProt Accessions	Q2YDW7, Q8C0J9	Gene names	SETD8
Domain Architecture	No domain graphic available
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8).

SETD8_HUMAN
NC score	0.312043 (rank : 25)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	150	Target Neighborhood Hits	114	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NQR1, Q86W83, Q8TD09	Gene names	SETD8, PRSET7, SET07, SET8
Domain Architecture
Description	Histone-lysine N-methyltransferase, H4 lysine-20 specific (EC 2.1.1.43) (Histone H4-K20 methyltransferase) (H4-K20-HMTase) (SET domain-containing lysine methyltransferase 8) (SET domain-containing protein 8) (PR/SET domain-containing protein 07) (PR/SET07) (PR-Set7).

PHF11_HUMAN
NC score	0.085380 (rank : 26)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	150	Target Neighborhood Hits	42	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UIL8, Q9Y5A2	Gene names	PHF11, BCAP
Domain Architecture	No domain graphic available
Description	PHD finger protein 11 (BRCA1 C-terminus-associated protein) (NY-REN-34 antigen).

VPS72_MOUSE
NC score	0.082024 (rank : 27)	θ value	0.21417 (rank : 34)
Query Neighborhood Hits	150	Target Neighborhood Hits	286	Shared Neighborhood Hits	15
SwissProt Accessions	Q62481, Q3U2N4, Q810A9, Q99K81	Gene names	Vps72, Tcfl1, Yl1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

BAZ2B_HUMAN
NC score	0.076518 (rank : 28)	θ value	0.21417 (rank : 29)
Query Neighborhood Hits	150	Target Neighborhood Hits	803	Shared Neighborhood Hits	43
SwissProt Accessions	Q9UIF8, Q96EA1, Q96SQ8, Q9P252, Q9Y4N8	Gene names	BAZ2B, KIAA1476
Domain Architecture
Description	Bromodomain adjacent to zinc finger domain 2B (hWALp4).

TARSH_HUMAN
NC score	0.073849 (rank : 29)	θ value	0.21417 (rank : 33)
Query Neighborhood Hits	150	Target Neighborhood Hits	768	Shared Neighborhood Hits	41
SwissProt Accessions	Q7Z7G0, Q6ZW20, Q6ZW22, Q9C082, Q9UFI6	Gene names	ABI3BP, NESHBP, TARSH
Domain Architecture	No domain graphic available
Description	Target of Nesh-SH3 precursor (Tarsh) (Nesh-binding protein) (NeshBP) (ABI gene family member 3-binding protein).

RAI1_MOUSE
NC score	0.068838 (rank : 30)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	150	Target Neighborhood Hits	344	Shared Neighborhood Hits	25
SwissProt Accessions	Q61818, Q6ZPH7, Q8CEV1	Gene names	Rai1, Kiaa1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

VPS72_HUMAN
NC score	0.066822 (rank : 31)	θ value	1.81305 (rank : 66)
Query Neighborhood Hits	150	Target Neighborhood Hits	274	Shared Neighborhood Hits	13
SwissProt Accessions	Q15906, Q53GJ2, Q5U0R4	Gene names	VPS72, TCFL1, YL1
Domain Architecture
Description	Vacuolar protein sorting-associated protein 72 homolog (Transcription factor-like 1) (Protein YL-1).

MPP8_HUMAN
NC score	0.066082 (rank : 32)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	150	Target Neighborhood Hits	948	Shared Neighborhood Hits	39
SwissProt Accessions	Q99549, Q86TK3, Q9BTP1	Gene names	MPHOSPH8, MPP8
Domain Architecture	No domain graphic available
Description	M-phase phosphoprotein 8.

MDC1_MOUSE
NC score	0.065955 (rank : 33)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	150	Target Neighborhood Hits	998	Shared Neighborhood Hits	49
SwissProt Accessions	Q5PSV9, Q5U4D3, Q6ZQH7	Gene names	Mdc1, Kiaa0170
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1.

PHF6_HUMAN
NC score	0.065293 (rank : 34)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	150	Target Neighborhood Hits	37	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IWS0, Q96JK3, Q9BRU0	Gene names	PHF6, KIAA1823
Domain Architecture	No domain graphic available
Description	PHD finger protein 6 (PHD-like zinc finger protein).

CBX3_MOUSE
NC score	0.064469 (rank : 35)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	150	Target Neighborhood Hits	39	Shared Neighborhood Hits	4
SwissProt Accessions	P23198, Q921C4	Gene names	Cbx3
Domain Architecture
Description	Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein) (M32).

PHF10_HUMAN
NC score	0.064442 (rank : 36)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	150	Target Neighborhood Hits	151	Shared Neighborhood Hits	13
SwissProt Accessions	Q8WUB8, Q2YDA3, Q9BXD2, Q9NV26	Gene names	PHF10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10 (XAP135).

CBX3_HUMAN
NC score	0.063829 (rank : 37)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	150	Target Neighborhood Hits	36	Shared Neighborhood Hits	4
SwissProt Accessions	Q13185, Q96CD7, Q99409, Q9BVS3, Q9P0Z6	Gene names	CBX3
Domain Architecture
Description	Chromobox protein homolog 3 (Heterochromatin protein 1 homolog gamma) (HP1 gamma) (Modifier 2 protein) (HECH).

NACAM_MOUSE
NC score	0.063697 (rank : 38)	θ value	3.0926 (rank : 80)
Query Neighborhood Hits	150	Target Neighborhood Hits	1866	Shared Neighborhood Hits	67
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

ANK2_HUMAN
NC score	0.063321 (rank : 39)	θ value	0.163984 (rank : 27)
Query Neighborhood Hits	150	Target Neighborhood Hits	1615	Shared Neighborhood Hits	63
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

PHF6_MOUSE
NC score	0.063163 (rank : 40)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	150	Target Neighborhood Hits	39	Shared Neighborhood Hits	8
SwissProt Accessions	Q9D4J7, Q80T86, Q8BYT8, Q8C1B5	Gene names	Phf6, Kiaa1823
Domain Architecture	No domain graphic available
Description	PHD finger protein 6.

TCF20_HUMAN
NC score	0.063062 (rank : 41)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	150	Target Neighborhood Hits	323	Shared Neighborhood Hits	25
SwissProt Accessions	Q9UGU0, O14528, Q13078, Q4V353, Q9H4M0	Gene names	TCF20, KIAA0292, SPBP
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP) (AR1).

PHF10_MOUSE
NC score	0.062466 (rank : 42)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	150	Target Neighborhood Hits	131	Shared Neighborhood Hits	10
SwissProt Accessions	Q9D8M7, Q99LV5	Gene names	Phf10
Domain Architecture	No domain graphic available
Description	PHD finger protein 10.

CBX1_HUMAN
NC score	0.062384 (rank : 43)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	150	Target Neighborhood Hits	44	Shared Neighborhood Hits	5
SwissProt Accessions	P83916, P23197	Gene names	CBX1, CBX
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25) (HP1Hsbeta) (p25beta).

CBX1_MOUSE
NC score	0.062384 (rank : 44)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	150	Target Neighborhood Hits	44	Shared Neighborhood Hits	5
SwissProt Accessions	P83917, P23197	Gene names	Cbx1, Cbx
Domain Architecture
Description	Chromobox protein homolog 1 (Heterochromatin protein 1 homolog beta) (HP1 beta) (Modifier 1 protein) (M31) (Heterochromatin protein p25).

RAI1_HUMAN
NC score	0.061269 (rank : 45)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	150	Target Neighborhood Hits	360	Shared Neighborhood Hits	18
SwissProt Accessions	Q7Z5J4, Q8N3B4, Q8ND08, Q8WU64, Q96JK5, Q9H1C1, Q9H1C2, Q9UF69	Gene names	RAI1, KIAA1820
Domain Architecture	No domain graphic available
Description	Retinoic acid-induced protein 1.

SETD7_MOUSE
NC score	0.061225 (rank : 46)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	150	Target Neighborhood Hits	39	Shared Neighborhood Hits	13
SwissProt Accessions	Q8VHL1	Gene names	Setd7, Set7
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET7 (EC 2.1.1.43) (Histone H3-K4 methyltransferase) (H3-K4-HMTase) (SET domain-containing protein 7).

SETD7_HUMAN
NC score	0.060133 (rank : 47)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	150	Target Neighborhood Hits	37	Shared Neighborhood Hits	13
SwissProt Accessions	Q8WTS6, Q9C0E6	Gene names	SETD7, KIAA1717, SET7
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-4 specific SET7 (EC 2.1.1.43) (Histone H3-K4 methyltransferase) (H3-K4-HMTase) (SET domain-containing protein 7) (Set9) (SET7/9).

MDC1_HUMAN
NC score	0.059806 (rank : 48)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	150	Target Neighborhood Hits	1446	Shared Neighborhood Hits	56
SwissProt Accessions	Q14676, Q5JP55, Q5JP56, Q5ST83, Q68CQ3, Q86Z06, Q96QC2	Gene names	MDC1, KIAA0170, NFBD1
Domain Architecture	No domain graphic available
Description	Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1).

PRP2_MOUSE
NC score	0.059378 (rank : 49)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	150	Target Neighborhood Hits	347	Shared Neighborhood Hits	33
SwissProt Accessions	P05142	Gene names	Prh1, Prp
Domain Architecture	No domain graphic available
Description	Proline-rich protein MP-2 precursor.

CBX5_HUMAN
NC score	0.059348 (rank : 50)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	150	Target Neighborhood Hits	70	Shared Neighborhood Hits	5
SwissProt Accessions	P45973	Gene names	CBX5, HP1A
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha) (Antigen p25).

SRRM1_MOUSE
NC score	0.059074 (rank : 51)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	150	Target Neighborhood Hits	966	Shared Neighborhood Hits	56
SwissProt Accessions	Q52KI8, O70495, Q9CVG5	Gene names	Srrm1, Pop101
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Plenty-of-prolines 101).

CBX5_MOUSE
NC score	0.058901 (rank : 52)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	150	Target Neighborhood Hits	67	Shared Neighborhood Hits	5
SwissProt Accessions	Q61686, Q9CS35, Q9CXD1	Gene names	Cbx5, Hp1a
Domain Architecture
Description	Chromobox protein homolog 5 (Heterochromatin protein 1 homolog alpha) (HP1 alpha).

TCF20_MOUSE
NC score	0.057375 (rank : 53)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	150	Target Neighborhood Hits	396	Shared Neighborhood Hits	22
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

SON_HUMAN
NC score	0.057271 (rank : 54)	θ value	0.125558 (rank : 26)
Query Neighborhood Hits	150	Target Neighborhood Hits	1568	Shared Neighborhood Hits	58
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

PRP1_HUMAN
NC score	0.056982 (rank : 55)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	150	Target Neighborhood Hits	385	Shared Neighborhood Hits	33
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

WASIP_MOUSE
NC score	0.056687 (rank : 56)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	150	Target Neighborhood Hits	392	Shared Neighborhood Hits	33
SwissProt Accessions	Q8K1I7, Q3U0U8	Gene names	Waspip, Wip
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein).

PI5PA_HUMAN
NC score	0.056478 (rank : 57)	θ value	0.125558 (rank : 25)
Query Neighborhood Hits	150	Target Neighborhood Hits	749	Shared Neighborhood Hits	45
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

SHAN1_HUMAN
NC score	0.055285 (rank : 58)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	150	Target Neighborhood Hits	1041	Shared Neighborhood Hits	43
SwissProt Accessions	Q9Y566, Q9NYW9	Gene names	SHANK1
Domain Architecture
Description	SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP).

DPF1_HUMAN
NC score	0.055271 (rank : 59)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	150	Target Neighborhood Hits	136	Shared Neighborhood Hits	9
SwissProt Accessions	Q92782	Gene names	DPF1, NEUD4
Domain Architecture
Description	Zinc-finger protein neuro-d4 (D4, zinc and double PHD fingers family 1).

NCOA6_HUMAN
NC score	0.054932 (rank : 60)	θ value	1.06291 (rank : 53)
Query Neighborhood Hits	150	Target Neighborhood Hits	1202	Shared Neighborhood Hits	44
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

SRRM1_HUMAN
NC score	0.054675 (rank : 61)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	150	Target Neighborhood Hits	690	Shared Neighborhood Hits	45
SwissProt Accessions	Q8IYB3, O60585, Q5VVN4	Gene names	SRRM1, SRM160
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 1 (Ser/Arg-related nuclear matrix protein) (SR-related nuclear matrix protein of 160 kDa) (SRm160).

ANR22_HUMAN
NC score	0.054035 (rank : 62)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	150	Target Neighborhood Hits	243	Shared Neighborhood Hits	7
SwissProt Accessions	Q5VYY1, Q8WU06	Gene names	ANKRD22
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 22.

BASP_HUMAN
NC score	0.053760 (rank : 63)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	150	Target Neighborhood Hits	321	Shared Neighborhood Hits	27
SwissProt Accessions	P80723, O43596, Q5U0S0	Gene names	BASP1, NAP22
Domain Architecture	No domain graphic available
Description	Brain acid soluble protein 1 (BASP1 protein) (Neuronal axonal membrane protein NAP-22) (22 kDa neuronal tissue-enriched acidic protein).

MAP4_HUMAN
NC score	0.053575 (rank : 64)	θ value	0.47712 (rank : 41)
Query Neighborhood Hits	150	Target Neighborhood Hits	428	Shared Neighborhood Hits	29
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

ANR11_HUMAN
NC score	0.053204 (rank : 65)	θ value	6.88961 (rank : 115)
Query Neighborhood Hits	150	Target Neighborhood Hits	1289	Shared Neighborhood Hits	58
SwissProt Accessions	Q6UB99, Q6NTG1, Q6QMF8	Gene names	ANKRD11, ANCO1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 11 (Ankyrin repeat-containing cofactor 1).

GSCR1_HUMAN
NC score	0.053201 (rank : 66)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	150	Target Neighborhood Hits	674	Shared Neighborhood Hits	42
SwissProt Accessions	Q9NZM4	Gene names	GLTSCR1
Domain Architecture	No domain graphic available
Description	Glioma tumor suppressor candidate region gene 1 protein.

WASIP_HUMAN
NC score	0.052956 (rank : 67)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	150	Target Neighborhood Hits	458	Shared Neighborhood Hits	33
SwissProt Accessions	O43516, Q15220, Q6MZU9, Q9BU37, Q9UNP1	Gene names	WASPIP, WIP
Domain Architecture	No domain graphic available
Description	Wiskott-Aldrich syndrome protein-interacting protein (WASP-interacting protein) (PRPL-2 protein).

MYST4_HUMAN
NC score	0.052489 (rank : 68)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	150	Target Neighborhood Hits	671	Shared Neighborhood Hits	45
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

LAD1_MOUSE
NC score	0.052393 (rank : 69)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	150	Target Neighborhood Hits	391	Shared Neighborhood Hits	25
SwissProt Accessions	P57016	Gene names	Lad1
Domain Architecture	No domain graphic available
Description	Ladinin 1 (Lad-1) (Linear IgA disease autoantigen).

PRR12_HUMAN
NC score	0.051900 (rank : 70)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	150	Target Neighborhood Hits	460	Shared Neighborhood Hits	42
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

MYST3_HUMAN
NC score	0.051796 (rank : 71)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	150	Target Neighborhood Hits	772	Shared Neighborhood Hits	47
SwissProt Accessions	Q92794	Gene names	MYST3, MOZ, RUNXBP2, ZNF220
Domain Architecture
Description	Histone acetyltransferase MYST3 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 3) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3) (Runt-related transcription factor-binding protein 2) (Monocytic leukemia zinc finger protein) (Zinc finger protein 220).

PHF7_HUMAN
NC score	0.051629 (rank : 72)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	150	Target Neighborhood Hits	71	Shared Neighborhood Hits	9
SwissProt Accessions	Q9BWX1	Gene names	PHF7
Domain Architecture	No domain graphic available
Description	PHD finger protein 7 (Testis development protein NYD-SP6).

WIRE_HUMAN
NC score	0.051215 (rank : 73)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	150	Target Neighborhood Hits	329	Shared Neighborhood Hits	32
SwissProt Accessions	Q8TF74, Q658J8, Q71RE1, Q8TE44	Gene names	WIRE, WICH
Domain Architecture	No domain graphic available
Description	WIP-related protein (WASP-interacting protein-related protein) (WIP- and CR16-homologous protein).

TXND2_HUMAN
NC score	0.051148 (rank : 74)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	150	Target Neighborhood Hits	793	Shared Neighborhood Hits	38
SwissProt Accessions	Q86VQ3, Q8N7U4, Q96RX3, Q9H0L8	Gene names	TXNDC2, SPTRX, SPTRX1
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1).

MARCS_HUMAN
NC score	0.050509 (rank : 75)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	150	Target Neighborhood Hits	204	Shared Neighborhood Hits	19
SwissProt Accessions	P29966, Q2LA83, Q5TDB7	Gene names	MARCKS, MACS, PRKCSL
Domain Architecture	No domain graphic available
Description	Myristoylated alanine-rich C-kinase substrate (MARCKS) (Protein kinase C substrate, 80 kDa protein, light chain) (PKCSL) (80K-L protein).

CSKI1_HUMAN
NC score	0.050500 (rank : 76)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	150	Target Neighborhood Hits	997	Shared Neighborhood Hits	44
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

INVS_MOUSE
NC score	0.050462 (rank : 77)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	150	Target Neighborhood Hits	609	Shared Neighborhood Hits	24
SwissProt Accessions	O89019, O88849	Gene names	Invs, Inv, Nphp2
Domain Architecture	No domain graphic available
Description	Inversin (Inversion of embryo turning protein) (Nephrocystin-2).

RSF1_HUMAN
NC score	0.050432 (rank : 78)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	150	Target Neighborhood Hits	539	Shared Neighborhood Hits	34
SwissProt Accessions	Q96T23, Q86X86, Q9H3L8, Q9NVZ8, Q9NYU0	Gene names	RSF1, HBXAP, XAP8
Domain Architecture	No domain graphic available
Description	Remodeling and spacing factor 1 (Rsf-1) (Hepatitis B virus X- associated protein) (HBV pX-associated protein 8) (p325 subunit of RSF chromatin remodelling complex).

CBP_MOUSE
NC score	0.050161 (rank : 79)	θ value	4.03905 (rank : 86)
Query Neighborhood Hits	150	Target Neighborhood Hits	1051	Shared Neighborhood Hits	49
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CTTB2_HUMAN
NC score	0.050105 (rank : 80)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	150	Target Neighborhood Hits	1061	Shared Neighborhood Hits	50
SwissProt Accessions	Q8WZ74, O43389, Q7LG11, Q9C0A5	Gene names	CTTNBP2, C7orf8, CORTBP2, KIAA1758
Domain Architecture	No domain graphic available
Description	Cortactin-binding protein 2 (CortBP2).

ANR49_MOUSE
NC score	0.050091 (rank : 81)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	150	Target Neighborhood Hits	285	Shared Neighborhood Hits	7
SwissProt Accessions	Q8VE42, Q9Z2S1	Gene names	Ankrd49, Fgif, Gbif
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 49 (Fetal globin-inducing factor) (Fetal globin-increasing factor).

ANKR6_HUMAN
NC score	0.050012 (rank : 82)	θ value	θ > 10 (rank : 151)
Query Neighborhood Hits	150	Target Neighborhood Hits	439	Shared Neighborhood Hits	17
SwissProt Accessions	Q9Y2G4, Q9NU24, Q9UFQ9	Gene names	ANKRD6, KIAA0957
Domain Architecture
Description	Ankyrin repeat domain-containing protein 6.

BSN_MOUSE
NC score	0.049856 (rank : 83)	θ value	2.36792 (rank : 68)
Query Neighborhood Hits	150	Target Neighborhood Hits	2057	Shared Neighborhood Hits	82
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

RTP3_MOUSE
NC score	0.049385 (rank : 84)	θ value	8.99809 (rank : 145)
Query Neighborhood Hits	150	Target Neighborhood Hits	374	Shared Neighborhood Hits	32
SwissProt Accessions	Q5QGU6, Q8VDC2	Gene names	Rtp3, Tmem7
Domain Architecture	No domain graphic available
Description	Receptor-transporting protein 3 (Transmembrane protein 7).

MILK2_HUMAN
NC score	0.048181 (rank : 85)	θ value	1.38821 (rank : 56)
Query Neighborhood Hits	150	Target Neighborhood Hits	457	Shared Neighborhood Hits	42
SwissProt Accessions	Q8IY33, Q7RTP4, Q7Z655, Q8TEQ4, Q9H5F9	Gene names
Domain Architecture
Description	MICAL-like protein 2.

NFH_MOUSE
NC score	0.047707 (rank : 86)	θ value	0.0563607 (rank : 24)
Query Neighborhood Hits	150	Target Neighborhood Hits	2247	Shared Neighborhood Hits	80
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

CIC_MOUSE
NC score	0.047287 (rank : 87)	θ value	0.47712 (rank : 39)
Query Neighborhood Hits	150	Target Neighborhood Hits	742	Shared Neighborhood Hits	48
SwissProt Accessions	Q924A2, Q6PDJ8, Q8CGE4, Q8CHH0, Q9CW61	Gene names	Cic, Kiaa0306
Domain Architecture	No domain graphic available
Description	Protein capicua homolog.

CO002_HUMAN
NC score	0.047177 (rank : 88)	θ value	2.36792 (rank : 69)
Query Neighborhood Hits	150	Target Neighborhood Hits	387	Shared Neighborhood Hits	22
SwissProt Accessions	Q9NZP6	Gene names	C15orf2
Domain Architecture	No domain graphic available
Description	Protein C15orf2.

IASPP_HUMAN
NC score	0.046385 (rank : 89)	θ value	4.03905 (rank : 90)
Query Neighborhood Hits	150	Target Neighborhood Hits	688	Shared Neighborhood Hits	34
SwissProt Accessions	Q8WUF5, Q2PNZ9, Q5DU71, Q5I1X4, Q6P1R7, Q6PKF8, Q9Y290	Gene names	PPP1R13L, IASPP, NKIP1, PPP1R13BL, RAI
Domain Architecture
Description	RelA-associated inhibitor (Inhibitor of ASPP protein) (Protein iASPP) (PPP1R13B-like protein) (NFkB-interacting protein 1).

CRSP7_HUMAN
NC score	0.045205 (rank : 90)	θ value	1.06291 (rank : 50)
Query Neighborhood Hits	150	Target Neighborhood Hits	247	Shared Neighborhood Hits	14
SwissProt Accessions	O95402	Gene names	CRSP7, ARC70
Domain Architecture
Description	CRSP complex subunit 7 (Cofactor required for Sp1 transcriptional activation subunit 7) (Transcriptional coactivator CRSP70) (Activator- recruited cofactor 70 kDa component) (ARC70).

MYCD_HUMAN
NC score	0.043569 (rank : 91)	θ value	1.06291 (rank : 52)
Query Neighborhood Hits	150	Target Neighborhood Hits	167	Shared Neighborhood Hits	15
SwissProt Accessions	Q8IZQ8, Q8N7Q1	Gene names	MYOCD, MYCD
Domain Architecture
Description	Myocardin.

MBB1A_HUMAN
NC score	0.042364 (rank : 92)	θ value	3.0926 (rank : 77)
Query Neighborhood Hits	150	Target Neighborhood Hits	665	Shared Neighborhood Hits	31
SwissProt Accessions	Q9BQG0, Q86VM3, Q9BW49, Q9P0V5, Q9UF99	Gene names	MYBBP1A, P160
Domain Architecture	No domain graphic available
Description	Myb-binding protein 1A.

CBP_HUMAN
NC score	0.042224 (rank : 93)	θ value	6.88961 (rank : 119)
Query Neighborhood Hits	150	Target Neighborhood Hits	941	Shared Neighborhood Hits	43
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CT2NL_MOUSE
NC score	0.041434 (rank : 94)	θ value	0.62314 (rank : 43)
Query Neighborhood Hits	150	Target Neighborhood Hits	902	Shared Neighborhood Hits	45
SwissProt Accessions	Q99LJ0, Q6ZPR0, Q8BSV1	Gene names	Cttnbp2nl, Kiaa1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

JADE2_MOUSE
NC score	0.040610 (rank : 95)	θ value	5.27518 (rank : 104)
Query Neighborhood Hits	150	Target Neighborhood Hits	560	Shared Neighborhood Hits	31
SwissProt Accessions	Q6ZQF7, Q3UHD5, Q6IE83	Gene names	Phf15, Jade2, Kiaa0239
Domain Architecture	No domain graphic available
Description	Protein Jade-2 (PHD finger protein 15).

GRIN1_HUMAN
NC score	0.040503 (rank : 96)	θ value	1.06291 (rank : 51)
Query Neighborhood Hits	150	Target Neighborhood Hits	681	Shared Neighborhood Hits	29
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

NOTC2_HUMAN
NC score	0.039645 (rank : 97)	θ value	0.62314 (rank : 44)
Query Neighborhood Hits	150	Target Neighborhood Hits	1113	Shared Neighborhood Hits	46
SwissProt Accessions	Q04721, Q99734, Q9H240	Gene names	NOTCH2
Domain Architecture
Description	Neurogenic locus notch homolog protein 2 precursor (Notch 2) (hN2) [Contains: Notch 2 extracellular truncation; Notch 2 intracellular domain].

MUC1_HUMAN
NC score	0.038294 (rank : 98)	θ value	4.03905 (rank : 94)
Query Neighborhood Hits	150	Target Neighborhood Hits	975	Shared Neighborhood Hits	42
SwissProt Accessions	P15941, P13931, P15942, P17626, Q14128, Q14876, Q16437, Q16442, Q16615, Q9BXA4, Q9UE75, Q9UE76, Q9UQL1, Q9Y4J2	Gene names	MUC1
Domain Architecture
Description	Mucin-1 precursor (MUC-1) (Polymorphic epithelial mucin) (PEM) (PEMT) (Episialin) (Tumor-associated mucin) (Carcinoma-associated mucin) (Tumor-associated epithelial membrane antigen) (EMA) (H23AG) (Peanut- reactive urinary mucin) (PUM) (Breast carcinoma-associated antigen DF3) (CD227 antigen).

LEO1_MOUSE
NC score	0.037256 (rank : 99)	θ value	4.03905 (rank : 92)
Query Neighborhood Hits	150	Target Neighborhood Hits	946	Shared Neighborhood Hits	26
SwissProt Accessions	Q5XJE5, Q640R1	Gene names	Leo1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein LEO1.

MKL1_MOUSE
NC score	0.036988 (rank : 100)	θ value	6.88961 (rank : 126)
Query Neighborhood Hits	150	Target Neighborhood Hits	667	Shared Neighborhood Hits	33
SwissProt Accessions	Q8K4J6	Gene names	Mkl1, Bsac
Domain Architecture
Description	MKL/myocardin-like protein 1 (Myocardin-related transcription factor A) (MRTF-A) (Megakaryoblastic leukemia 1 protein homolog) (Basic SAP coiled-coil transcription activator).

SAPS1_HUMAN
NC score	0.036500 (rank : 101)	θ value	3.0926 (rank : 85)
Query Neighborhood Hits	150	Target Neighborhood Hits	704	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UPN7, Q504V2, Q6NVJ6, Q9BU97	Gene names	SAPS1, KIAA1115
Domain Architecture
Description	SAPS domain family member 1.

K1802_HUMAN
NC score	0.036044 (rank : 102)	θ value	6.88961 (rank : 124)
Query Neighborhood Hits	150	Target Neighborhood Hits	1378	Shared Neighborhood Hits	46
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

RASF8_MOUSE
NC score	0.036024 (rank : 103)	θ value	2.36792 (rank : 71)
Query Neighborhood Hits	150	Target Neighborhood Hits	391	Shared Neighborhood Hits	29
SwissProt Accessions	Q8CJ96, Q8CCW4, Q9CU91	Gene names	Rassf8
Domain Architecture	No domain graphic available
Description	Ras association domain-containing protein 8 (Carcinoma-associated protein HOJ-1 homolog).

WTAP_HUMAN
NC score	0.033831 (rank : 104)	θ value	4.03905 (rank : 101)
Query Neighborhood Hits	150	Target Neighborhood Hits	262	Shared Neighborhood Hits	21
SwissProt Accessions	Q15007, Q96T28, Q9BYJ7, Q9H4E2	Gene names	WTAP, KIAA0105
Domain Architecture	No domain graphic available
Description	Wilms' tumor 1-associating protein (WT1-associated protein) (Putative pre-mRNA-splicing regulator female-lethal(2D) homolog).

SPTN4_HUMAN
NC score	0.033585 (rank : 105)	θ value	0.365318 (rank : 38)
Query Neighborhood Hits	150	Target Neighborhood Hits	570	Shared Neighborhood Hits	35
SwissProt Accessions	Q9H254, Q9H1K7, Q9H1K8, Q9H1K9, Q9H3G8, Q9HCD0	Gene names	SPTBN4, KIAA1642, SPTBN3
Domain Architecture
Description	Spectrin beta chain, brain 3 (Spectrin, non-erythroid beta chain 3) (Beta-IV spectrin).

LTBP3_MOUSE
NC score	0.032594 (rank : 106)	θ value	0.21417 (rank : 32)
Query Neighborhood Hits	150	Target Neighborhood Hits	475	Shared Neighborhood Hits	20
SwissProt Accessions	Q61810, Q8BNQ6	Gene names	Ltbp3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

RGS3_HUMAN
NC score	0.032456 (rank : 107)	θ value	1.38821 (rank : 57)
Query Neighborhood Hits	150	Target Neighborhood Hits	1375	Shared Neighborhood Hits	39
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

GOGA1_HUMAN
NC score	0.031949 (rank : 108)	θ value	0.21417 (rank : 31)
Query Neighborhood Hits	150	Target Neighborhood Hits	1222	Shared Neighborhood Hits	42
SwissProt Accessions	Q92805, Q8IYZ9	Gene names	GOLGA1
Domain Architecture
Description	Golgin subfamily A member 1 (Golgin-97).

RRBP1_MOUSE
NC score	0.031892 (rank : 109)	θ value	0.47712 (rank : 42)
Query Neighborhood Hits	150	Target Neighborhood Hits	1650	Shared Neighborhood Hits	56
SwissProt Accessions	Q99PL5, Q99PK5, Q99PK6, Q99PK7, Q99PK8, Q99PK9, Q99PL0, Q99PL1, Q99PL2, Q99PL3, Q99PL4, Q9CS20	Gene names	Rrbp1
Domain Architecture
Description	Ribosome-binding protein 1 (Ribosome receptor protein) (mRRp).

CT2NL_HUMAN
NC score	0.031618 (rank : 110)	θ value	8.99809 (rank : 138)
Query Neighborhood Hits	150	Target Neighborhood Hits	1059	Shared Neighborhood Hits	49
SwissProt Accessions	Q9P2B4, Q96B40	Gene names	CTTNBP2NL, KIAA1433
Domain Architecture	No domain graphic available
Description	CTTNBP2 N-terminal-like protein.

SOX30_MOUSE
NC score	0.031329 (rank : 111)	θ value	6.88961 (rank : 132)
Query Neighborhood Hits	150	Target Neighborhood Hits	374	Shared Neighborhood Hits	31
SwissProt Accessions	Q8CGW4	Gene names	Sox30
Domain Architecture
Description	Transcription factor SOX-30.

AKAP2_HUMAN
NC score	0.031211 (rank : 112)	θ value	1.06291 (rank : 48)
Query Neighborhood Hits	150	Target Neighborhood Hits	507	Shared Neighborhood Hits	26
SwissProt Accessions	Q9Y2D5, Q9UG26	Gene names	AKAP2, KIAA0920
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2).

LTBP3_HUMAN
NC score	0.030038 (rank : 113)	θ value	0.47712 (rank : 40)
Query Neighborhood Hits	150	Target Neighborhood Hits	502	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NS15, O15107, Q96HB9, Q9H7K2, Q9UFN4	Gene names	LTBP3
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 3 precursor (LTBP-3).

DIAP1_HUMAN
NC score	0.029983 (rank : 114)	θ value	6.88961 (rank : 120)
Query Neighborhood Hits	150	Target Neighborhood Hits	784	Shared Neighborhood Hits	55
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

ALMS1_MOUSE
NC score	0.029786 (rank : 115)	θ value	1.38821 (rank : 55)
Query Neighborhood Hits	150	Target Neighborhood Hits	181	Shared Neighborhood Hits	13
SwissProt Accessions	Q8K4E0, Q6A084, Q8C9N9	Gene names	Alms1, Kiaa0328
Domain Architecture	No domain graphic available
Description	Alstrom syndrome protein 1 homolog.

ASPH_HUMAN
NC score	0.029199 (rank : 116)	θ value	2.36792 (rank : 67)
Query Neighborhood Hits	150	Target Neighborhood Hits	158	Shared Neighborhood Hits	5
SwissProt Accessions	Q12797	Gene names	ASPH
Domain Architecture
Description	Aspartyl/asparaginyl beta-hydroxylase (EC 1.14.11.16) (Aspartate beta- hydroxylase) (ASP beta-hydroxylase) (Peptide-aspartate beta- dioxygenase).

CEL_HUMAN
NC score	0.029180 (rank : 117)	θ value	0.365318 (rank : 37)
Query Neighborhood Hits	150	Target Neighborhood Hits	896	Shared Neighborhood Hits	33
SwissProt Accessions	P19835, Q16398	Gene names	CEL, BAL
Domain Architecture
Description	Bile salt-activated lipase precursor (EC 3.1.1.3) (EC 3.1.1.13) (BAL) (Bile salt-stimulated lipase) (BSSL) (Carboxyl ester lipase) (Sterol esterase) (Cholesterol esterase) (Pancreatic lysophospholipase).

NRX2B_HUMAN
NC score	0.028960 (rank : 118)	θ value	1.81305 (rank : 63)
Query Neighborhood Hits	150	Target Neighborhood Hits	481	Shared Neighborhood Hits	24
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

CUTL1_MOUSE
NC score	0.028324 (rank : 119)	θ value	3.0926 (rank : 75)
Query Neighborhood Hits	150	Target Neighborhood Hits	1620	Shared Neighborhood Hits	63
SwissProt Accessions	P53564, O08994, P70301, Q571L6, Q91ZD2	Gene names	Cutl1, Cux, Cux1, Kiaa4047
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein Cux).

TTF2_MOUSE
NC score	0.027323 (rank : 120)	θ value	0.279714 (rank : 36)
Query Neighborhood Hits	150	Target Neighborhood Hits	364	Shared Neighborhood Hits	15
SwissProt Accessions	Q5NC05, Q5M924	Gene names	Ttf2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2).

SYNE2_HUMAN
NC score	0.027013 (rank : 121)	θ value	6.88961 (rank : 134)
Query Neighborhood Hits	150	Target Neighborhood Hits	1323	Shared Neighborhood Hits	42
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

TTC16_HUMAN
NC score	0.026951 (rank : 122)	θ value	1.81305 (rank : 65)
Query Neighborhood Hits	150	Target Neighborhood Hits	417	Shared Neighborhood Hits	15
SwissProt Accessions	Q8NEE8, Q5JU66, Q96M72	Gene names	TTC16
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 16 (TPR repeat protein 16).

SYNE1_HUMAN
NC score	0.026316 (rank : 123)	θ value	4.03905 (rank : 98)
Query Neighborhood Hits	150	Target Neighborhood Hits	1484	Shared Neighborhood Hits	43
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

JPH3_HUMAN
NC score	0.025962 (rank : 124)	θ value	0.163984 (rank : 28)
Query Neighborhood Hits	150	Target Neighborhood Hits	80	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WXH2, Q8N471, Q9HDC3, Q9HDC4	Gene names	JPH3, JP3
Domain Architecture
Description	Junctophilin-3 (Junctophilin type 3) (JP-3).

NFRKB_MOUSE
NC score	0.025811 (rank : 125)	θ value	8.99809 (rank : 143)
Query Neighborhood Hits	150	Target Neighborhood Hits	393	Shared Neighborhood Hits	25
SwissProt Accessions	Q6PIJ4, Q8BWV5, Q8K0X6	Gene names	Nfrkb
Domain Architecture	No domain graphic available
Description	Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B).

CENPF_HUMAN
NC score	0.025398 (rank : 126)	θ value	1.06291 (rank : 49)
Query Neighborhood Hits	150	Target Neighborhood Hits	1932	Shared Neighborhood Hits	56
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

LTBP4_MOUSE
NC score	0.025138 (rank : 127)	θ value	0.813845 (rank : 47)
Query Neighborhood Hits	150	Target Neighborhood Hits	607	Shared Neighborhood Hits	28
SwissProt Accessions	Q8K4G1, Q8K4G0	Gene names	Ltbp4
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 4 precursor (LTBP-4).

MYH3_HUMAN
NC score	0.025067 (rank : 128)	θ value	0.279714 (rank : 35)
Query Neighborhood Hits	150	Target Neighborhood Hits	1660	Shared Neighborhood Hits	46
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

ZF106_HUMAN
NC score	0.024841 (rank : 129)	θ value	2.36792 (rank : 72)
Query Neighborhood Hits	150	Target Neighborhood Hits	470	Shared Neighborhood Hits	17
SwissProt Accessions	Q9H2Y7, Q6NSD9, Q6PEK1, Q86T43, Q86T45, Q86T50, Q86T58, Q86TA9, Q96M37, Q9H7B8	Gene names	ZFP106, ZNF474
Domain Architecture	No domain graphic available
Description	Zinc finger protein 106 homolog (Zfp-106) (Zinc finger protein 474).

ERRFI_HUMAN
NC score	0.024799 (rank : 130)	θ value	2.36792 (rank : 70)
Query Neighborhood Hits	150	Target Neighborhood Hits	72	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UJM3, Q9NTG9, Q9UD05	Gene names	ERRFI1, MIG6
Domain Architecture	No domain graphic available
Description	ERBB receptor feedback inhibitor 1 (Mitogen-inducible gene 6 protein) (Mig-6).

BPA1_MOUSE
NC score	0.024703 (rank : 131)	θ value	6.88961 (rank : 117)
Query Neighborhood Hits	150	Target Neighborhood Hits	1477	Shared Neighborhood Hits	41
SwissProt Accessions	Q91ZU6, Q91ZU7	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoforms 1/2/3/4 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CTGE5_MOUSE
NC score	0.024610 (rank : 132)	θ value	3.0926 (rank : 74)
Query Neighborhood Hits	150	Target Neighborhood Hits	928	Shared Neighborhood Hits	45
SwissProt Accessions	Q8R311, Q8CIE3	Gene names	Ctage5, Mea6, Mgea6
Domain Architecture	No domain graphic available
Description	Cutaneous T-cell lymphoma-associated antigen 5 homolog (cTAGE-5 protein) (Meningioma-expressed antigen 6).

CO020_HUMAN
NC score	0.024408 (rank : 133)	θ value	8.99809 (rank : 137)
Query Neighborhood Hits	150	Target Neighborhood Hits	10	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H611	Gene names	C15orf20
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C15orf20.

TRIPB_HUMAN
NC score	0.024373 (rank : 134)	θ value	5.27518 (rank : 113)
Query Neighborhood Hits	150	Target Neighborhood Hits	1587	Shared Neighborhood Hits	50
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

KIF4A_MOUSE
NC score	0.024230 (rank : 135)	θ value	0.813845 (rank : 46)
Query Neighborhood Hits	150	Target Neighborhood Hits	1033	Shared Neighborhood Hits	45
SwissProt Accessions	P33174	Gene names	Kif4a, Kif4, Kns4
Domain Architecture
Description	Chromosome-associated kinesin KIF4A (Chromokinesin).

SMCE1_MOUSE
NC score	0.024213 (rank : 136)	θ value	8.99809 (rank : 147)
Query Neighborhood Hits	150	Target Neighborhood Hits	409	Shared Neighborhood Hits	25
SwissProt Accessions	O54941, Q8BPD9	Gene names	Smarce1, Baf57
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator chromatin subfamily E member 1 (BRG1-associated factor 57).

FYCO1_MOUSE
NC score	0.024126 (rank : 137)	θ value	1.81305 (rank : 59)
Query Neighborhood Hits	150	Target Neighborhood Hits	1059	Shared Neighborhood Hits	36
SwissProt Accessions	Q8VDC1, Q3V385, Q7TMT0, Q8BJN2	Gene names	Fyco1
Domain Architecture	No domain graphic available
Description	FYVE and coiled-coil domain-containing protein 1.

ZN638_HUMAN
NC score	0.023999 (rank : 138)	θ value	4.03905 (rank : 102)
Query Neighborhood Hits	150	Target Neighborhood Hits	343	Shared Neighborhood Hits	25
SwissProt Accessions	Q14966, Q53R34, Q5XJ05, Q68DP3, Q6P2H2, Q7Z3T7, Q8NF92, Q8TCA1, Q9H2G1, Q9NP37	Gene names	ZNF638, NP220, ZFML
Domain Architecture	No domain graphic available
Description	Zinc finger protein 638 (Nuclear protein 220) (Zinc-finger matrin-like protein) (Cutaneous T-cell lymphoma-associated antigen se33-1) (CTCL tumor antigen se33-1).

GOGA4_MOUSE
NC score	0.023792 (rank : 139)	θ value	4.03905 (rank : 88)
Query Neighborhood Hits	150	Target Neighborhood Hits	1939	Shared Neighborhood Hits	52
SwissProt Accessions	Q91VW5, O70365, Q8CGH6	Gene names	Golga4
Domain Architecture
Description	Golgin subfamily A member 4 (tGolgin-1).

PKHA6_HUMAN
NC score	0.023782 (rank : 140)	θ value	3.0926 (rank : 83)
Query Neighborhood Hits	150	Target Neighborhood Hits	556	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y2H5	Gene names	PLEKHA6, KIAA0969, PEPP3
Domain Architecture	No domain graphic available
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

LPP_HUMAN
NC score	0.023658 (rank : 141)	θ value	8.99809 (rank : 141)
Query Neighborhood Hits	150	Target Neighborhood Hits	775	Shared Neighborhood Hits	35
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

MNAB_MOUSE
NC score	0.023508 (rank : 142)	θ value	4.03905 (rank : 93)
Query Neighborhood Hits	150	Target Neighborhood Hits	231	Shared Neighborhood Hits	14
SwissProt Accessions	P0C090	Gene names	Mnab
Domain Architecture	No domain graphic available
Description	Membrane-associated nucleic acid-binding protein.

SRBP1_MOUSE
NC score	0.022894 (rank : 143)	θ value	8.99809 (rank : 148)
Query Neighborhood Hits	150	Target Neighborhood Hits	384	Shared Neighborhood Hits	25
SwissProt Accessions	Q9WTN3	Gene names	Srebf1, Srebp1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

EFS_MOUSE
NC score	0.022847 (rank : 144)	θ value	6.88961 (rank : 121)
Query Neighborhood Hits	150	Target Neighborhood Hits	389	Shared Neighborhood Hits	25
SwissProt Accessions	Q64355	Gene names	Efs, Sin
Domain Architecture
Description	Embryonal Fyn-associated substrate (SRC-interacting protein) (Signal- integrating protein).

UTRO_HUMAN
NC score	0.022674 (rank : 145)	θ value	5.27518 (rank : 114)
Query Neighborhood Hits	150	Target Neighborhood Hits	960	Shared Neighborhood Hits	40
SwissProt Accessions	P46939	Gene names	UTRN, DMDL
Domain Architecture
Description	Utrophin (Dystrophin-related protein 1) (DRP1) (DRP).

EPAS1_MOUSE
NC score	0.022215 (rank : 146)	θ value	0.21417 (rank : 30)
Query Neighborhood Hits	150	Target Neighborhood Hits	94	Shared Neighborhood Hits	5
SwissProt Accessions	P97481, O08787, O55046	Gene names	Epas1, Hif2a
Domain Architecture
Description	Endothelial PAS domain-containing protein 1 (EPAS-1) (Hypoxia- inducible factor 2 alpha) (HIF-2 alpha) (HIF2 alpha) (HIF-1 alpha-like factor) (MHLF) (HIF-related factor) (HRF).

NRX2A_HUMAN
NC score	0.022158 (rank : 147)	θ value	1.81305 (rank : 62)
Query Neighborhood Hits	150	Target Neighborhood Hits	614	Shared Neighborhood Hits	29
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

UT14A_HUMAN
NC score	0.021682 (rank : 148)	θ value	4.03905 (rank : 100)
Query Neighborhood Hits	150	Target Neighborhood Hits	168	Shared Neighborhood Hits	14
SwissProt Accessions	Q9BVJ6, Q5JYF1	Gene names	UTP14A
Domain Architecture	No domain graphic available
Description	U3 small nucleolar RNA-associated protein 14 homolog A (Antigen NY-CO- 16).

AZI1_HUMAN
NC score	0.021382 (rank : 149)	θ value	8.99809 (rank : 136)
Query Neighborhood Hits	150	Target Neighborhood Hits	1000	Shared Neighborhood Hits	41
SwissProt Accessions	Q9UPN4, Q96F50	Gene names	AZI1, CEP131, KIAA1118
Domain Architecture	No domain graphic available
Description	5-azacytidine-induced protein 1 (Pre-acrosome localization protein 1) (Centrosomal protein of 131 kDa) (Cep131 protein).

NELL2_HUMAN
NC score	0.020938 (rank : 150)	θ value	1.81305 (rank : 60)
Query Neighborhood Hits	150	Target Neighborhood Hits	449	Shared Neighborhood Hits	14
SwissProt Accessions	Q99435	Gene names	NELL2, NRP2
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (Nel-related protein 2).

NELL2_MOUSE
NC score	0.020892 (rank : 151)	θ value	1.81305 (rank : 61)
Query Neighborhood Hits	150	Target Neighborhood Hits	436	Shared Neighborhood Hits	15
SwissProt Accessions	Q61220	Gene names	Nell2, Mel91
Domain Architecture
Description	Protein kinase C-binding protein NELL2 precursor (NEL-like protein 2) (MEL91 protein).

RUFY2_HUMAN
NC score	0.020463 (rank : 152)	θ value	6.88961 (rank : 130)
Query Neighborhood Hits	150	Target Neighborhood Hits	1208	Shared Neighborhood Hits	42
SwissProt Accessions	Q8WXA3, Q96P51, Q9P1Z1	Gene names	RUFY2, KIAA1537, RABIP4R
Domain Architecture	No domain graphic available
Description	RUN and FYVE domain-containing protein 2 (Rab4-interacting protein related).

MYH10_MOUSE
NC score	0.020354 (rank : 153)	θ value	3.0926 (rank : 79)
Query Neighborhood Hits	150	Target Neighborhood Hits	1612	Shared Neighborhood Hits	44
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

SOX15_HUMAN
NC score	0.020263 (rank : 154)	θ value	1.06291 (rank : 54)
Query Neighborhood Hits	150	Target Neighborhood Hits	134	Shared Neighborhood Hits	9
SwissProt Accessions	O60248, P35717, Q9Y6W7	Gene names	SOX15, SOX12, SOX20, SOX26, SOX27
Domain Architecture
Description	SOX-15 protein (SOX-20 protein) (SOX-12 protein).

MYH10_HUMAN
NC score	0.020179 (rank : 155)	θ value	3.0926 (rank : 78)
Query Neighborhood Hits	150	Target Neighborhood Hits	1620	Shared Neighborhood Hits	44
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH11_HUMAN
NC score	0.020107 (rank : 156)	θ value	6.88961 (rank : 127)
Query Neighborhood Hits	150	Target Neighborhood Hits	1806	Shared Neighborhood Hits	51
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MAVS_MOUSE
NC score	0.020083 (rank : 157)	θ value	6.88961 (rank : 125)
Query Neighborhood Hits	150	Target Neighborhood Hits	170	Shared Neighborhood Hits	10
SwissProt Accessions	Q8VCF0	Gene names	Mavs, Ips1, Visa
Domain Architecture	No domain graphic available
Description	Mitochondrial antiviral signaling protein (Interferon-beta promoter stimulator protein 1) (IPS-1) (Virus-induced signaling adapter) (CARD adapter inducing interferon-beta) (Cardif).

RYBP_HUMAN
NC score	0.019916 (rank : 158)	θ value	6.88961 (rank : 131)
Query Neighborhood Hits	150	Target Neighborhood Hits	50	Shared Neighborhood Hits	6
SwissProt Accessions	Q8N488, Q9P2W5, Q9UMW4	Gene names	RYBP, DEDAF, YEAF1
Domain Architecture	No domain graphic available
Description	RING1 and YY1-binding protein (Death effector domain-associated factor) (DED-associated factor) (YY1 and E4TF1-associated factor 1) (Apoptin-associating protein 1) (APAP-1).

MY18A_MOUSE
NC score	0.019449 (rank : 159)	θ value	8.99809 (rank : 142)
Query Neighborhood Hits	150	Target Neighborhood Hits	1989	Shared Neighborhood Hits	49
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

SMC4_HUMAN
NC score	0.019422 (rank : 160)	θ value	5.27518 (rank : 110)
Query Neighborhood Hits	150	Target Neighborhood Hits	937	Shared Neighborhood Hits	38
SwissProt Accessions	Q9NTJ3, O95752, Q8NDL4, Q9UNT9	Gene names	SMC4L1, CAPC, SMC4
Domain Architecture
Description	Structural maintenance of chromosomes 4-like 1 protein (Chromosome- associated polypeptide C) (hCAP-C) (XCAP-C homolog).

FLNB_HUMAN
NC score	0.019329 (rank : 161)	θ value	3.0926 (rank : 76)
Query Neighborhood Hits	150	Target Neighborhood Hits	111	Shared Neighborhood Hits	10
SwissProt Accessions	O75369, Q13706, Q8WXS9, Q8WXT0, Q8WXT1, Q8WXT2, Q9NRB5, Q9NT26, Q9UEV9	Gene names	FLNB, FLN1L, FLN3, TABP, TAP
Domain Architecture
Description	Filamin-B (FLN-B) (Beta-filamin) (Actin-binding-like protein) (Thyroid autoantigen) (Truncated actin-binding protein) (Truncated ABP) (ABP- 280 homolog) (ABP-278) (Filamin 3) (Filamin homolog 1) (Fh1).

STAB2_MOUSE
NC score	0.019232 (rank : 162)	θ value	4.03905 (rank : 96)
Query Neighborhood Hits	150	Target Neighborhood Hits	528	Shared Neighborhood Hits	20
SwissProt Accessions	Q8R4U0, Q8BM87	Gene names	Stab2
Domain Architecture	No domain graphic available
Description	Stabilin-2 precursor [Contains: Short form stabilin-2].

MCPH1_MOUSE
NC score	0.019218 (rank : 163)	θ value	5.27518 (rank : 106)
Query Neighborhood Hits	150	Target Neighborhood Hits	116	Shared Neighborhood Hits	5
SwissProt Accessions	Q7TT79, Q8BNI9, Q8C9I7	Gene names	Mcph1
Domain Architecture
Description	Microcephalin.

MYH11_MOUSE
NC score	0.019124 (rank : 164)	θ value	5.27518 (rank : 107)
Query Neighborhood Hits	150	Target Neighborhood Hits	1777	Shared Neighborhood Hits	45
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

NTNG1_HUMAN
NC score	0.019120 (rank : 165)	θ value	3.0926 (rank : 81)
Query Neighborhood Hits	150	Target Neighborhood Hits	247	Shared Neighborhood Hits	14
SwissProt Accessions	Q9Y2I2, Q5VU86, Q5VU87, Q5VU89, Q5VU90, Q5VU91, Q7Z2Y3, Q8N633	Gene names	NTNG1, KIAA0976, LMNT1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

FIBA_HUMAN
NC score	0.018927 (rank : 166)	θ value	5.27518 (rank : 103)
Query Neighborhood Hits	150	Target Neighborhood Hits	132	Shared Neighborhood Hits	7
SwissProt Accessions	P02671, Q9BX62, Q9UCH2	Gene names	FGA
Domain Architecture
Description	Fibrinogen alpha chain precursor [Contains: Fibrinopeptide A].

JAG1_MOUSE
NC score	0.018906 (rank : 167)	θ value	4.03905 (rank : 91)
Query Neighborhood Hits	150	Target Neighborhood Hits	518	Shared Neighborhood Hits	18
SwissProt Accessions	Q9QXX0	Gene names	Jag1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (CD339 antigen).

SOX17_MOUSE
NC score	0.018862 (rank : 168)	θ value	1.81305 (rank : 64)
Query Neighborhood Hits	150	Target Neighborhood Hits	223	Shared Neighborhood Hits	16
SwissProt Accessions	Q61473, Q61472, Q62248	Gene names	Sox17, Sox-17
Domain Architecture
Description	Transcription factor SOX-17.

PHAR3_MOUSE
NC score	0.018792 (rank : 169)	θ value	3.0926 (rank : 82)
Query Neighborhood Hits	150	Target Neighborhood Hits	206	Shared Neighborhood Hits	14
SwissProt Accessions	Q8BYK5, Q8BYS8, Q8C058, Q9DB87	Gene names	Phactr3, Scapin1
Domain Architecture	No domain graphic available
Description	Phosphatase and actin regulator 3 (Scapinin) (Scaffold-associated PP1- inhibiting protein).

PDZD8_HUMAN
NC score	0.018709 (rank : 170)	θ value	6.88961 (rank : 128)
Query Neighborhood Hits	150	Target Neighborhood Hits	185	Shared Neighborhood Hits	14
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

DACT1_MOUSE
NC score	0.018313 (rank : 171)	θ value	4.03905 (rank : 87)
Query Neighborhood Hits	150	Target Neighborhood Hits	93	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R4A3, Q80VG9, Q8BP49, Q9JK89	Gene names	Dact1, Thyex3
Domain Architecture	No domain graphic available
Description	Dapper homolog 1 (MDpr1) (Frodo) (Thymus-expressed novel gene 3 protein).

HMMR_HUMAN
NC score	0.017622 (rank : 172)	θ value	8.99809 (rank : 139)
Query Neighborhood Hits	150	Target Neighborhood Hits	1082	Shared Neighborhood Hits	34
SwissProt Accessions	O75330, Q92767	Gene names	HMMR, IHABP, RHAMM
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility) (CD168 antigen).

JAG1_HUMAN
NC score	0.017399 (rank : 173)	θ value	6.88961 (rank : 123)
Query Neighborhood Hits	150	Target Neighborhood Hits	514	Shared Neighborhood Hits	17
SwissProt Accessions	P78504, O14902, O15122, Q15816	Gene names	JAG1, JAGL1
Domain Architecture
Description	Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen).

TCGAP_MOUSE
NC score	0.017337 (rank : 174)	θ value	5.27518 (rank : 112)
Query Neighborhood Hits	150	Target Neighborhood Hits	409	Shared Neighborhood Hits	26
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

RYBP_MOUSE
NC score	0.016441 (rank : 175)	θ value	8.99809 (rank : 146)
Query Neighborhood Hits	150	Target Neighborhood Hits	39	Shared Neighborhood Hits	5
SwissProt Accessions	Q8CCI5, Q9WVK2	Gene names	Rybp, Dedaf
Domain Architecture	No domain graphic available
Description	RING1 and YY1-binding protein (Death effector domain-associated factor) (DED-associated factor).

HS74L_HUMAN
NC score	0.014822 (rank : 176)	θ value	4.03905 (rank : 89)
Query Neighborhood Hits	150	Target Neighborhood Hits	141	Shared Neighborhood Hits	15
SwissProt Accessions	O95757, Q4W5M5, Q8IWA2	Gene names	HSPA4L, APG1, OSP94
Domain Architecture
Description	Heat shock 70 kDa protein 4L (Osmotic stress protein 94) (Heat shock 70-related protein APG-1).

NTNG1_MOUSE
NC score	0.014675 (rank : 177)	θ value	8.99809 (rank : 144)
Query Neighborhood Hits	150	Target Neighborhood Hits	246	Shared Neighborhood Hits	14
SwissProt Accessions	Q8R4G0, Q68FE5, Q69ZU3, Q8R4F3, Q8R4F4, Q8R4F5, Q8R4F6, Q8R4F7, Q8R4F8, Q8R4F9, Q9ESR3, Q9ESR4, Q9ESR5, Q9ESR6, Q9ESR7, Q9ESR8	Gene names	Ntng1, Kiaa0976, Lmnt1
Domain Architecture
Description	Netrin G1 precursor (Laminet-1).

NID1_MOUSE
NC score	0.014585 (rank : 178)	θ value	5.27518 (rank : 108)
Query Neighborhood Hits	150	Target Neighborhood Hits	335	Shared Neighborhood Hits	13
SwissProt Accessions	P10493, Q8BQI3, Q8C3U8, Q8C9P6	Gene names	Nid1, Ent
Domain Architecture
Description	Nidogen-1 precursor (Entactin).

SHC2_MOUSE
NC score	0.014417 (rank : 179)	θ value	1.38821 (rank : 58)
Query Neighborhood Hits	150	Target Neighborhood Hits	144	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BMC3	Gene names	Shc2, Sck, ShcB
Domain Architecture
Description	SHC-transforming protein 2 (SH2 domain protein C2) (Src homology 2 domain-containing-transforming protein C2) (Protein Sck) (Protein Sli).

SSH3_HUMAN
NC score	0.014305 (rank : 180)	θ value	5.27518 (rank : 111)
Query Neighborhood Hits	150	Target Neighborhood Hits	75	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TE77, Q6PK42, Q76I75, Q8N9L8, Q8WYL0, Q9NV45, Q9NWZ7	Gene names	SSH3, SSH3L
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 3 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-3L) (hSSH-3L).

LAMC2_MOUSE
NC score	0.013861 (rank : 181)	θ value	8.99809 (rank : 140)
Query Neighborhood Hits	150	Target Neighborhood Hits	614	Shared Neighborhood Hits	30
SwissProt Accessions	Q61092	Gene names	Lamc2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain).

JHD2B_HUMAN
NC score	0.013580 (rank : 182)	θ value	5.27518 (rank : 105)
Query Neighborhood Hits	150	Target Neighborhood Hits	171	Shared Neighborhood Hits	11
SwissProt Accessions	Q7LBC6, Q9BVH6, Q9BW93, Q9BZ52, Q9NYF4, Q9UPS0	Gene names	JMJD1B, C5orf7, JHDM2B, KIAA1082
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2B (EC 1.14.11.-) (Jumonji domain-containing protein 1B) (Nuclear protein 5qNCA).

UBQL3_MOUSE
NC score	0.012874 (rank : 183)	θ value	4.03905 (rank : 99)
Query Neighborhood Hits	150	Target Neighborhood Hits	120	Shared Neighborhood Hits	7
SwissProt Accessions	Q8C5U9	Gene names	Ubqln3
Domain Architecture
Description	Ubiquilin-3.

RECQ4_MOUSE
NC score	0.012453 (rank : 184)	θ value	3.0926 (rank : 84)
Query Neighborhood Hits	150	Target Neighborhood Hits	206	Shared Neighborhood Hits	8
SwissProt Accessions	Q75NR7, Q76MT1, Q99PV9	Gene names	Recql4, Recq4
Domain Architecture	No domain graphic available
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4).

SENP2_MOUSE
NC score	0.011588 (rank : 185)	θ value	5.27518 (rank : 109)
Query Neighborhood Hits	150	Target Neighborhood Hits	18	Shared Neighborhood Hits	2
SwissProt Accessions	Q91ZX6, Q544T8, Q9D4Z0	Gene names	Senp2, Smt3ip2
Domain Architecture
Description	Sentrin-specific protease 2 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP2) (SUMO-1/Smt3-specific isopeptidase 2) (Smt3ip2) (Axam2).

SSH1_HUMAN
NC score	0.011167 (rank : 186)	θ value	6.88961 (rank : 133)
Query Neighborhood Hits	150	Target Neighborhood Hits	164	Shared Neighborhood Hits	14
SwissProt Accessions	Q8WYL5, Q6P6C0, Q8N9A7, Q8WYL3, Q8WYL4, Q9P2P8	Gene names	SSH1, KIAA1298, SSH1L
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 1 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-1L) (hSSH-1L).

ITSN2_MOUSE
NC score	0.010097 (rank : 187)	θ value	6.88961 (rank : 122)
Query Neighborhood Hits	150	Target Neighborhood Hits	1371	Shared Neighborhood Hits	36
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

RPGR_HUMAN
NC score	0.010085 (rank : 188)	θ value	6.88961 (rank : 129)
Query Neighborhood Hits	150	Target Neighborhood Hits	279	Shared Neighborhood Hits	13
SwissProt Accessions	Q92834, O00702, O00737, Q8N5T6, Q93039, Q9HD29, Q9UMR1	Gene names	RPGR, RP3, XLRP3
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator.

UTX_HUMAN
NC score	0.009578 (rank : 189)	θ value	8.99809 (rank : 150)
Query Neighborhood Hits	150	Target Neighborhood Hits	161	Shared Neighborhood Hits	6
SwissProt Accessions	O15550	Gene names	UTX
Domain Architecture
Description	Ubiquitously transcribed X chromosome tetratricopeptide repeat protein (Ubiquitously transcribed TPR protein on the X chromosome).

APBA2_MOUSE
NC score	0.006988 (rank : 190)	θ value	6.88961 (rank : 116)
Query Neighborhood Hits	150	Target Neighborhood Hits	219	Shared Neighborhood Hits	4
SwissProt Accessions	P98084, Q6PAJ2	Gene names	Apba2, X11l
Domain Architecture	No domain graphic available
Description	Amyloid beta A4 precursor protein-binding family A member 2 (Neuron- specific X11L protein) (Neuronal Munc18-1-interacting protein 2) (Mint-2) (Adapter protein X11beta).

TRI62_HUMAN
NC score	0.006286 (rank : 191)	θ value	8.99809 (rank : 149)
Query Neighborhood Hits	150	Target Neighborhood Hits	584	Shared Neighborhood Hits	29
SwissProt Accessions	Q9BVG3, Q9NVG0	Gene names	TRIM62
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 62.

BTBD5_HUMAN
NC score	0.005004 (rank : 192)	θ value	3.0926 (rank : 73)
Query Neighborhood Hits	150	Target Neighborhood Hits	190	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NXS3	Gene names	BTBD5
Domain Architecture
Description	BTB/POZ domain-containing protein 5.

TMPS2_HUMAN
NC score	0.004655 (rank : 193)	θ value	6.88961 (rank : 135)
Query Neighborhood Hits	150	Target Neighborhood Hits	252	Shared Neighborhood Hits	6
SwissProt Accessions	O15393, Q9BXX1	Gene names	TMPRSS2, PRSS10
Domain Architecture
Description	Transmembrane protease, serine 2 precursor (EC 3.4.21.-) [Contains: Transmembrane protease, serine 2 non-catalytic chain; Transmembrane protease, serine 2 catalytic chain].

BTBD5_MOUSE
NC score	0.003927 (rank : 194)	θ value	6.88961 (rank : 118)
Query Neighborhood Hits	150	Target Neighborhood Hits	189	Shared Neighborhood Hits	3
SwissProt Accessions	Q9CR40, Q9CYV0	Gene names	Btbd5
Domain Architecture
Description	BTB/POZ domain-containing protein 5.

SUHW4_HUMAN
NC score	0.003428 (rank : 195)	θ value	4.03905 (rank : 97)
Query Neighborhood Hits	150	Target Neighborhood Hits	860	Shared Neighborhood Hits	12
SwissProt Accessions	Q6N043, Q6MZM6, Q6N085, Q9H0U5, Q9HCI8, Q9NXS0	Gene names	SUHW4, KIAA1584
Domain Architecture	No domain graphic available
Description	Suppressor of hairy wing homolog 4.

OR2J1_HUMAN
NC score	0.002127 (rank : 196)	θ value	0.62314 (rank : 45)
Query Neighborhood Hits	150	Target Neighborhood Hits	758	Shared Neighborhood Hits	4
SwissProt Accessions	Q9GZK6, Q9GZK1	Gene names	OR2J1
Domain Architecture
Description	Olfactory receptor 2J1 (Olfactory receptor 6-5) (OR6-5) (Hs6M1-4).

OR2J3_HUMAN
NC score	-0.000030 (rank : 197)	θ value	4.03905 (rank : 95)
Query Neighborhood Hits	150	Target Neighborhood Hits	748	Shared Neighborhood Hits	4
SwissProt Accessions	O76001, Q96R15, Q9GZK5, Q9GZL4, Q9GZL5	Gene names	OR2J3
Domain Architecture
Description	Olfactory receptor 2J3 (Olfactory receptor 6-6) (OR6-6) (Hs6M1-3).