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Network neighborhood for query Sequence : SSH1_HUMAN

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SSH1_HUMAN
SwissProt Accessions	Q8WYL5, Q6P6C0, Q8N9A7, Q8WYL3, Q8WYL4, Q9P2P8	Gene names	SSH1, KIAA1298, SSH1L
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 1 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-1L) (hSSH-1L).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SSH1_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	164	Target Neighborhood Hits	164	Shared Neighborhood Hits	164
SwissProt Accessions	Q8WYL5, Q6P6C0, Q8N9A7, Q8WYL3, Q8WYL4, Q9P2P8	Gene names	SSH1, KIAA1298, SSH1L
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 1 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-1L) (hSSH-1L).

SSH1_MOUSE
θ value	0 (rank : 2)	NC score	0.989644 (rank : 2)
Query Neighborhood Hits	164	Target Neighborhood Hits	107	Shared Neighborhood Hits	63
SwissProt Accessions	Q76I79, Q3TDG3, Q69ZM4, Q811E5	Gene names	Ssh1, Kiaa1298, Ssh1l
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 1 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-1L) (mSSH-1L).

SSH2_HUMAN
θ value	0 (rank : 3)	NC score	0.962722 (rank : 5)
Query Neighborhood Hits	164	Target Neighborhood Hits	140	Shared Neighborhood Hits	53
SwissProt Accessions	Q76I76, Q8TDB5, Q8WYL1, Q8WYL2, Q96F40, Q96H36, Q9C0D8	Gene names	SSH2, KIAA1725, SSH2L
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 2 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-2L) (hSSH-2L).

SSH2_MOUSE
θ value	0 (rank : 4)	NC score	0.965279 (rank : 3)
Query Neighborhood Hits	164	Target Neighborhood Hits	119	Shared Neighborhood Hits	51
SwissProt Accessions	Q5SW75, Q3TDK8, Q3TYP8, Q3U2K3, Q5F268, Q5SW74, Q69ZC3, Q76I78	Gene names	Ssh2, Kiaa1725, Ssh2l
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 2 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-2L) (mSSH-2L).

SSH3_MOUSE
θ value	5.61992e-127 (rank : 5)	NC score	0.963383 (rank : 4)
Query Neighborhood Hits	164	Target Neighborhood Hits	69	Shared Neighborhood Hits	49
SwissProt Accessions	Q8K330, Q3UDX0	Gene names	Ssh3, Ssh3l
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 3 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-3L) (mSSH-3L).

SSH3_HUMAN
θ value	3.52827e-121 (rank : 6)	NC score	0.960700 (rank : 6)
Query Neighborhood Hits	164	Target Neighborhood Hits	75	Shared Neighborhood Hits	49
SwissProt Accessions	Q8TE77, Q6PK42, Q76I75, Q8N9L8, Q8WYL0, Q9NV45, Q9NWZ7	Gene names	SSH3, SSH3L
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 3 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-3L) (hSSH-3L).

DUS2_HUMAN
θ value	9.87957e-23 (rank : 7)	NC score	0.806299 (rank : 10)
Query Neighborhood Hits	164	Target Neighborhood Hits	67	Shared Neighborhood Hits	48
SwissProt Accessions	Q05923	Gene names	DUSP2, PAC1
Domain Architecture
Description	Dual specificity protein phosphatase 2 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase PAC-1).

DUS2_MOUSE
θ value	9.87957e-23 (rank : 8)	NC score	0.806252 (rank : 11)
Query Neighborhood Hits	164	Target Neighborhood Hits	86	Shared Neighborhood Hits	51
SwissProt Accessions	Q05922, Q60640	Gene names	Dusp2, Pac-1, Pac1
Domain Architecture
Description	Dual specificity protein phosphatase 2 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase PAC-1).

DUS9_HUMAN
θ value	3.75424e-22 (rank : 9)	NC score	0.813717 (rank : 9)
Query Neighborhood Hits	164	Target Neighborhood Hits	59	Shared Neighborhood Hits	48
SwissProt Accessions	Q99956	Gene names	DUSP9, MKP4
Domain Architecture
Description	Dual specificity protein phosphatase 9 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 4) (MAP kinase phosphatase 4) (MKP-4).

DUS1_HUMAN
θ value	8.36355e-22 (rank : 10)	NC score	0.787749 (rank : 22)
Query Neighborhood Hits	164	Target Neighborhood Hits	73	Shared Neighborhood Hits	50
SwissProt Accessions	P28562, Q2V508	Gene names	DUSP1, CL100, MKP1, PTPN10, VH1
Domain Architecture
Description	Dual specificity protein phosphatase 1 (EC 3.1.3.48) (EC 3.1.3.16) (MAP kinase phosphatase 1) (MKP-1) (Protein-tyrosine phosphatase CL100) (Dual specificity protein phosphatase hVH1).

DUS1_MOUSE
θ value	1.09232e-21 (rank : 11)	NC score	0.784427 (rank : 26)
Query Neighborhood Hits	164	Target Neighborhood Hits	72	Shared Neighborhood Hits	50
SwissProt Accessions	P28563	Gene names	Dusp1, 3ch134, Mkp1, Ptpn10, Ptpn16
Domain Architecture
Description	Dual specificity protein phosphatase 1 (EC 3.1.3.48) (EC 3.1.3.16) (MAP kinase phosphatase 1) (MKP-1) (Protein-tyrosine phosphatase 3CH134) (Protein-tyrosine phosphatase ERP).

DUS4_HUMAN
θ value	1.42661e-21 (rank : 12)	NC score	0.781771 (rank : 27)
Query Neighborhood Hits	164	Target Neighborhood Hits	77	Shared Neighborhood Hits	48
SwissProt Accessions	Q13115, Q13524	Gene names	DUSP4, MKP2, VH2
Domain Architecture
Description	Dual specificity protein phosphatase 4 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 2) (MAP kinase phosphatase 2) (MKP-2) (Dual specificity protein phosphatase hVH2).

DUS5_HUMAN
θ value	3.17815e-21 (rank : 13)	NC score	0.802236 (rank : 16)
Query Neighborhood Hits	164	Target Neighborhood Hits	82	Shared Neighborhood Hits	50
SwissProt Accessions	Q16690, Q12997	Gene names	DUSP5, VH3
Domain Architecture
Description	Dual specificity protein phosphatase 5 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase hVH3).

DUS6_HUMAN
θ value	3.17815e-21 (rank : 14)	NC score	0.787240 (rank : 24)
Query Neighborhood Hits	164	Target Neighborhood Hits	57	Shared Neighborhood Hits	46
SwissProt Accessions	Q16828, O75109, Q53Y75, Q9BSH6	Gene names	DUSP6, MKP3, PYST1
Domain Architecture
Description	Dual specificity protein phosphatase 6 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 3) (MAP kinase phosphatase 3) (MKP-3) (Dual specificity protein phosphatase PYST1).

DUS4_MOUSE
θ value	9.24701e-21 (rank : 15)	NC score	0.780882 (rank : 28)
Query Neighborhood Hits	164	Target Neighborhood Hits	75	Shared Neighborhood Hits	48
SwissProt Accessions	Q8BFV3	Gene names	Dusp4
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 4 (EC 3.1.3.48) (EC 3.1.3.16).

DUS7_HUMAN
θ value	9.24701e-21 (rank : 16)	NC score	0.787503 (rank : 23)
Query Neighborhood Hits	164	Target Neighborhood Hits	69	Shared Neighborhood Hits	50
SwissProt Accessions	Q16829, Q8NFJ0	Gene names	DUSP7, PYST2
Domain Architecture
Description	Dual specificity protein phosphatase 7 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase PYST2).

DUS10_HUMAN
θ value	1.2077e-20 (rank : 17)	NC score	0.794348 (rank : 20)
Query Neighborhood Hits	164	Target Neighborhood Hits	64	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y6W6	Gene names	DUSP10, MKP5
Domain Architecture
Description	Dual specificity protein phosphatase 10 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 5) (MAP kinase phosphatase 5) (MKP-5).

DUS10_MOUSE
θ value	1.2077e-20 (rank : 18)	NC score	0.795352 (rank : 19)
Query Neighborhood Hits	164	Target Neighborhood Hits	62	Shared Neighborhood Hits	48
SwissProt Accessions	Q9ESS0, Q9CZY9	Gene names	Dusp10, Mkp5
Domain Architecture
Description	Dual specificity protein phosphatase 10 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 5) (MAP kinase phosphatase 5) (MKP-5).

DUS6_MOUSE
θ value	1.2077e-20 (rank : 19)	NC score	0.785869 (rank : 25)
Query Neighborhood Hits	164	Target Neighborhood Hits	57	Shared Neighborhood Hits	46
SwissProt Accessions	Q9DBB1, Q542I5, Q9D7L4	Gene names	Dusp6, Mkp3
Domain Architecture
Description	Dual specificity protein phosphatase 6 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 3) (MAP kinase phosphatase 3) (MKP-3).

DUS8_HUMAN
θ value	5.07402e-19 (rank : 20)	NC score	0.762828 (rank : 31)
Query Neighborhood Hits	164	Target Neighborhood Hits	161	Shared Neighborhood Hits	61
SwissProt Accessions	Q13202	Gene names	DUSP8, VH5
Domain Architecture
Description	Dual specificity protein phosphatase 8 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase hVH-5).

DUS19_HUMAN
θ value	6.62687e-19 (rank : 21)	NC score	0.830068 (rank : 7)
Query Neighborhood Hits	164	Target Neighborhood Hits	52	Shared Neighborhood Hits	48
SwissProt Accessions	Q8WTR2, Q8WYN4	Gene names	DUSP19, DUSP17, SKRP1
Domain Architecture
Description	Dual specificity protein phosphatase 19 (EC 3.1.3.48) (EC 3.1.3.16) (Stress-activated protein kinase pathway-regulating phosphatase 1) (Protein phosphatase SKRP1).

DUS14_HUMAN
θ value	1.13037e-18 (rank : 22)	NC score	0.796504 (rank : 18)
Query Neighborhood Hits	164	Target Neighborhood Hits	64	Shared Neighborhood Hits	47
SwissProt Accessions	O95147	Gene names	DUSP14, MKP6
Domain Architecture
Description	Dual specificity protein phosphatase 14 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 6) (MAP kinase phosphatase 6) (MKP-6) (MKP-1-like protein tyrosine phosphatase) (MKP- L).

DUS14_MOUSE
θ value	1.13037e-18 (rank : 23)	NC score	0.799373 (rank : 17)
Query Neighborhood Hits	164	Target Neighborhood Hits	67	Shared Neighborhood Hits	48
SwissProt Accessions	Q9JLY7, Q9D715	Gene names	Dusp14, Mkp6
Domain Architecture
Description	Dual specificity protein phosphatase 14 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 6) (MAP kinase phosphatase 6) (MKP-6).

DUS8_MOUSE
θ value	1.92812e-18 (rank : 24)	NC score	0.767827 (rank : 30)
Query Neighborhood Hits	164	Target Neighborhood Hits	119	Shared Neighborhood Hits	56
SwissProt Accessions	O09112	Gene names	Dusp8, Nttp1
Domain Architecture
Description	Dual specificity protein phosphatase 8 (EC 3.1.3.48) (EC 3.1.3.16) (Neuronal tyrosine threonine phosphatase 1).

DUS16_HUMAN
θ value	5.60996e-18 (rank : 25)	NC score	0.775344 (rank : 29)
Query Neighborhood Hits	164	Target Neighborhood Hits	112	Shared Neighborhood Hits	55
SwissProt Accessions	Q9BY84, Q9C0G3	Gene names	DUSP16, KIAA1700, MKP7
Domain Architecture
Description	Dual specificity protein phosphatase 16 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 7) (MAP kinase phosphatase 7) (MKP-7).

DUS19_MOUSE
θ value	4.74913e-17 (rank : 26)	NC score	0.828316 (rank : 8)
Query Neighborhood Hits	164	Target Neighborhood Hits	58	Shared Neighborhood Hits	48
SwissProt Accessions	Q8K4T5	Gene names	Dusp19, Skrp1
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 19 (EC 3.1.3.48) (EC 3.1.3.16) (Stress-activated protein kinase pathway-regulating phosphatase 1) (Protein phosphatase SKRP1).

DUS22_HUMAN
θ value	5.25075e-16 (rank : 27)	NC score	0.805401 (rank : 14)
Query Neighborhood Hits	164	Target Neighborhood Hits	58	Shared Neighborhood Hits	50
SwissProt Accessions	Q9NRW4, Q59GW2, Q5VWR2, Q96AR1	Gene names	DUSP22, JSP1, MKPX
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 22 (EC 3.1.3.48) (EC 3.1.3.16) (JNK-stimulatory phosphatase-1) (JSP-1) (Mitogen-activated protein kinase phosphatase x) (LMW-DSP2).

DUS22_MOUSE
θ value	6.85773e-16 (rank : 28)	NC score	0.805437 (rank : 13)
Query Neighborhood Hits	164	Target Neighborhood Hits	57	Shared Neighborhood Hits	50
SwissProt Accessions	Q99N11, Q5SQN9, Q5SQP0	Gene names	Dusp22
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 22 (EC 3.1.3.48) (EC 3.1.3.16) (LMW-DSP2).

STYX_MOUSE
θ value	8.95645e-16 (rank : 29)	NC score	0.806080 (rank : 12)
Query Neighborhood Hits	164	Target Neighborhood Hits	62	Shared Neighborhood Hits	49
SwissProt Accessions	Q60969, Q3TMA3, Q60970, Q9DCF8	Gene names	Styx
Domain Architecture
Description	Serine/threonine/tyrosine-interacting protein (Protein tyrosine phosphatase-like protein) (Phosphoserine/threonine/tyrosine interaction protein).

STYX_HUMAN
θ value	4.44505e-15 (rank : 30)	NC score	0.804827 (rank : 15)
Query Neighborhood Hits	164	Target Neighborhood Hits	60	Shared Neighborhood Hits	50
SwissProt Accessions	Q8WUJ0, Q99850	Gene names	STYX
Domain Architecture
Description	Serine/threonine/tyrosine-interacting protein (Protein tyrosine phosphatase-like protein).

DUS15_HUMAN
θ value	7.09661e-13 (rank : 31)	NC score	0.788489 (rank : 21)
Query Neighborhood Hits	164	Target Neighborhood Hits	60	Shared Neighborhood Hits	49
SwissProt Accessions	Q9H1R2, Q5QP62, Q5QP63, Q5QP65, Q6PGN7, Q8N826, Q9BX24	Gene names	DUSP15, C20orf57, VHY
Domain Architecture
Description	Dual specificity protein phosphatase 15 (EC 3.1.3.48) (EC 3.1.3.16) (Vaccinia virus VH1-related dual-specific protein phosphatase Y) (VH1- related member Y).

DUS18_HUMAN
θ value	3.52202e-12 (rank : 32)	NC score	0.761397 (rank : 34)
Query Neighborhood Hits	164	Target Neighborhood Hits	52	Shared Neighborhood Hits	47
SwissProt Accessions	Q8NEJ0	Gene names	DUSP18, LMWDSP20
Domain Architecture
Description	Dual specificity protein phosphatase 18 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular weight dual specificity phosphatase 20).

DUS18_MOUSE
θ value	4.59992e-12 (rank : 33)	NC score	0.762402 (rank : 32)
Query Neighborhood Hits	164	Target Neighborhood Hits	53	Shared Neighborhood Hits	47
SwissProt Accessions	Q8VE01	Gene names	Dusp18
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 18 (EC 3.1.3.48) (EC 3.1.3.16).

DUS12_MOUSE
θ value	1.33837e-11 (rank : 34)	NC score	0.737033 (rank : 38)
Query Neighborhood Hits	164	Target Neighborhood Hits	60	Shared Neighborhood Hits	48
SwissProt Accessions	Q9D0T2, Q9EQD3	Gene names	Dusp12
Domain Architecture
Description	Dual specificity protein phosphatase 12 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity phosphatase T-DSP4) (Dual specificity phosphatase VH1).

DUS12_HUMAN
θ value	2.98157e-11 (rank : 35)	NC score	0.731019 (rank : 40)
Query Neighborhood Hits	164	Target Neighborhood Hits	60	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UNI6	Gene names	DUSP12
Domain Architecture
Description	Dual specificity protein phosphatase 12 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity tyrosine phosphatase YVH1).

DUS21_HUMAN
θ value	2.98157e-11 (rank : 36)	NC score	0.761599 (rank : 33)
Query Neighborhood Hits	164	Target Neighborhood Hits	52	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H596, Q6IAJ6, Q6YDQ8	Gene names	DUSP21, LMWDSP21
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 21 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular weight dual specificity phosphatase 21).

DUS3_HUMAN
θ value	9.59137e-10 (rank : 37)	NC score	0.751406 (rank : 35)
Query Neighborhood Hits	164	Target Neighborhood Hits	58	Shared Neighborhood Hits	46
SwissProt Accessions	P51452	Gene names	DUSP3, VHR
Domain Architecture
Description	Dual specificity protein phosphatase 3 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase VHR).

DUS3_MOUSE
θ value	1.63604e-09 (rank : 38)	NC score	0.750756 (rank : 36)
Query Neighborhood Hits	164	Target Neighborhood Hits	54	Shared Neighborhood Hits	46
SwissProt Accessions	Q9D7X3	Gene names	Dusp3
Domain Architecture
Description	Dual specificity protein phosphatase 3 (EC 3.1.3.48) (EC 3.1.3.16) (T- DSP11).

DUS13_MOUSE
θ value	2.13673e-09 (rank : 39)	NC score	0.740569 (rank : 37)
Query Neighborhood Hits	164	Target Neighborhood Hits	56	Shared Neighborhood Hits	47
SwissProt Accessions	Q9QYJ7	Gene names	Dusp13, Tmdp
Domain Architecture
Description	Dual specificity protein phosphatase 13 (EC 3.1.3.48) (EC 3.1.3.16) (Testis- and skeletal muscle-specific DSP) (Dual specificity tyrosine phosphatase TS-DSP6).

DUS13_HUMAN
θ value	1.38499e-08 (rank : 40)	NC score	0.732832 (rank : 39)
Query Neighborhood Hits	164	Target Neighborhood Hits	59	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UII6, Q5JSC6, Q96GC2	Gene names	DUSP13, TMDP
Domain Architecture
Description	Dual specificity protein phosphatase 13 (EC 3.1.3.48) (EC 3.1.3.16) (Testis- and skeletal-muscle-specific DSP) (Dual specificity phosphatase SKRP4).

STYL1_HUMAN
θ value	1.69304e-06 (rank : 41)	NC score	0.717371 (rank : 41)
Query Neighborhood Hits	164	Target Neighborhood Hits	43	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Y6J8, Q9UBP1, Q9UK06, Q9UK07, Q9UKG2, Q9UKG3	Gene names	STYXL1, DUSP24, MKSTYX
Domain Architecture
Description	Serine/threonine/tyrosine-interacting-like protein 1 (Dual specificity protein phosphatase 24) (Map kinase phosphatase-like protein MK-STYX) (Dual specificity phosphatase inhibitor MK-STYX).

ENL_HUMAN
θ value	0.00869519 (rank : 42)	NC score	0.051882 (rank : 54)
Query Neighborhood Hits	164	Target Neighborhood Hits	305	Shared Neighborhood Hits	18
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

NFH_MOUSE
θ value	0.0252991 (rank : 43)	NC score	0.022730 (rank : 79)
Query Neighborhood Hits	164	Target Neighborhood Hits	2247	Shared Neighborhood Hits	78
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

PTPM1_HUMAN
θ value	0.0431538 (rank : 44)	NC score	0.431434 (rank : 43)
Query Neighborhood Hits	164	Target Neighborhood Hits	60	Shared Neighborhood Hits	47
SwissProt Accessions	Q8WUK0, Q7Z557, Q96CR2, Q9BXV8	Gene names	PTPMT1, MOSP, PLIP
Domain Architecture	No domain graphic available
Description	Protein-tyrosine phosphatase mitochondrial 1, mitochondrial precursor (EC 3.1.3.48) (EC 3.1.3.16) (PTEN-like phosphatase) (Phosphoinositide lipid phosphatase).

PTPM1_MOUSE
θ value	0.0736092 (rank : 45)	NC score	0.454689 (rank : 42)
Query Neighborhood Hits	164	Target Neighborhood Hits	64	Shared Neighborhood Hits	48
SwissProt Accessions	Q66GT5, Q9CSJ8, Q9D622	Gene names	Ptpmt1, Plip
Domain Architecture	No domain graphic available
Description	Protein-tyrosine phosphatase mitochondrial 1, mitochondrial precursor (EC 3.1.3.48) (EC 3.1.3.16) (PTEN-like phosphatase) (Phosphoinositide lipid phosphatase).

RIMB1_HUMAN
θ value	0.0961366 (rank : 46)	NC score	0.018777 (rank : 90)
Query Neighborhood Hits	164	Target Neighborhood Hits	1479	Shared Neighborhood Hits	47
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

PELP1_MOUSE
θ value	0.125558 (rank : 47)	NC score	0.035392 (rank : 58)
Query Neighborhood Hits	164	Target Neighborhood Hits	709	Shared Neighborhood Hits	45
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

RGS3_HUMAN
θ value	0.125558 (rank : 48)	NC score	0.025238 (rank : 72)
Query Neighborhood Hits	164	Target Neighborhood Hits	1375	Shared Neighborhood Hits	69
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

ENAH_MOUSE
θ value	0.163984 (rank : 49)	NC score	0.026796 (rank : 70)
Query Neighborhood Hits	164	Target Neighborhood Hits	919	Shared Neighborhood Hits	46
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

LDB3_MOUSE
θ value	0.163984 (rank : 50)	NC score	0.016876 (rank : 95)
Query Neighborhood Hits	164	Target Neighborhood Hits	510	Shared Neighborhood Hits	31
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

RD23B_MOUSE
θ value	0.163984 (rank : 51)	NC score	0.031031 (rank : 61)
Query Neighborhood Hits	164	Target Neighborhood Hits	189	Shared Neighborhood Hits	15
SwissProt Accessions	P54728	Gene names	Rad23b, Mhr23b
Domain Architecture
Description	UV excision repair protein RAD23 homolog B (mHR23B) (XP-C repair- complementing complex 58 kDa protein) (p58).

NACAM_MOUSE
θ value	0.47712 (rank : 52)	NC score	0.029690 (rank : 64)
Query Neighborhood Hits	164	Target Neighborhood Hits	1866	Shared Neighborhood Hits	81
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

ODO2_MOUSE
θ value	0.47712 (rank : 53)	NC score	0.025495 (rank : 71)
Query Neighborhood Hits	164	Target Neighborhood Hits	85	Shared Neighborhood Hits	10
SwissProt Accessions	Q9D2G2	Gene names	Dlst
Domain Architecture	No domain graphic available
Description	Dihydrolipoyllysine-residue succinyltransferase component of 2- oxoglutarate dehydrogenase complex, mitochondrial precursor (EC 2.3.1.61) (Dihydrolipoamide succinyltransferase component of 2- oxoglutarate dehydrogenase complex) (E2) (E2K).

CC14A_MOUSE
θ value	0.62314 (rank : 54)	NC score	0.198889 (rank : 47)
Query Neighborhood Hits	164	Target Neighborhood Hits	117	Shared Neighborhood Hits	42
SwissProt Accessions	Q6GQT0, Q8BZ66	Gene names	Cdc14a
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14A (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog A).

MINT_HUMAN
θ value	0.62314 (rank : 55)	NC score	0.022583 (rank : 81)
Query Neighborhood Hits	164	Target Neighborhood Hits	1291	Shared Neighborhood Hits	48
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

SP7_MOUSE
θ value	0.62314 (rank : 56)	NC score	-0.000487 (rank : 162)
Query Neighborhood Hits	164	Target Neighborhood Hits	756	Shared Neighborhood Hits	12
SwissProt Accessions	Q8VI67, Q8C5R3, Q8C6A7	Gene names	Sp7, Osx
Domain Architecture	No domain graphic available
Description	Transcription factor Sp7 (Zinc finger protein osterix) (C22).

DYNA_HUMAN
θ value	0.813845 (rank : 57)	NC score	0.006989 (rank : 132)
Query Neighborhood Hits	164	Target Neighborhood Hits	1194	Shared Neighborhood Hits	27
SwissProt Accessions	Q14203, O95296, Q9BRM9, Q9UIU1, Q9UIU2	Gene names	DCTN1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued) (p135).

EPM2A_MOUSE
θ value	0.813845 (rank : 58)	NC score	0.255854 (rank : 44)
Query Neighborhood Hits	164	Target Neighborhood Hits	47	Shared Neighborhood Hits	37
SwissProt Accessions	Q9WUA5, Q8BY80	Gene names	Epm2a
Domain Architecture	No domain graphic available
Description	Laforin (EC 3.1.3.48) (EC 3.1.3.16) (Lafora PTPase) (LAFPTPase).

FA12_HUMAN
θ value	0.813845 (rank : 59)	NC score	0.001795 (rank : 158)
Query Neighborhood Hits	164	Target Neighborhood Hits	425	Shared Neighborhood Hits	5
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

LIPS_HUMAN
θ value	0.813845 (rank : 60)	NC score	0.027976 (rank : 67)
Query Neighborhood Hits	164	Target Neighborhood Hits	314	Shared Neighborhood Hits	28
SwissProt Accessions	Q05469, Q3LRT2, Q6NSL7	Gene names	LIPE
Domain Architecture
Description	Hormone-sensitive lipase (EC 3.1.1.79) (HSL).

BAT2_HUMAN
θ value	1.06291 (rank : 61)	NC score	0.027563 (rank : 69)
Query Neighborhood Hits	164	Target Neighborhood Hits	931	Shared Neighborhood Hits	54
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

CC14A_HUMAN
θ value	1.06291 (rank : 62)	NC score	0.188487 (rank : 49)
Query Neighborhood Hits	164	Target Neighborhood Hits	133	Shared Neighborhood Hits	45
SwissProt Accessions	Q9UNH5, O43171, O60727, O60728, Q8IXX0	Gene names	CDC14A
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14A (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog A).

EPM2A_HUMAN
θ value	1.06291 (rank : 63)	NC score	0.244313 (rank : 45)
Query Neighborhood Hits	164	Target Neighborhood Hits	47	Shared Neighborhood Hits	38
SwissProt Accessions	O95278, O95483, Q8IU96, Q8IX24, Q8IX25, Q9BS66, Q9UEN2	Gene names	EPM2A
Domain Architecture	No domain graphic available
Description	Laforin (EC 3.1.3.48) (EC 3.1.3.16) (Lafora PTPase) (LAFPTPase).

FOXJ2_HUMAN
θ value	1.06291 (rank : 64)	NC score	0.009309 (rank : 125)
Query Neighborhood Hits	164	Target Neighborhood Hits	239	Shared Neighborhood Hits	14
SwissProt Accessions	Q9P0K8, Q96PS9, Q9NSN5	Gene names	FOXJ2, FHX
Domain Architecture
Description	Forkhead box protein J2 (Fork head homologous X).

HN1L_HUMAN
θ value	1.06291 (rank : 65)	NC score	0.029492 (rank : 65)
Query Neighborhood Hits	164	Target Neighborhood Hits	88	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H910, Q6EIC7	Gene names	C16orf34, HN1L
Domain Architecture	No domain graphic available
Description	Hematological and neurological expressed 1-like protein (HN1-like protein).

MAP1B_MOUSE
θ value	1.06291 (rank : 66)	NC score	0.015378 (rank : 101)
Query Neighborhood Hits	164	Target Neighborhood Hits	977	Shared Neighborhood Hits	28
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

NFH_HUMAN
θ value	1.06291 (rank : 67)	NC score	0.012132 (rank : 110)
Query Neighborhood Hits	164	Target Neighborhood Hits	1242	Shared Neighborhood Hits	40
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

SEPT9_HUMAN
θ value	1.06291 (rank : 68)	NC score	0.014923 (rank : 104)
Query Neighborhood Hits	164	Target Neighborhood Hits	706	Shared Neighborhood Hits	48
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

TARA_HUMAN
θ value	1.06291 (rank : 69)	NC score	0.021581 (rank : 84)
Query Neighborhood Hits	164	Target Neighborhood Hits	1626	Shared Neighborhood Hits	63
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

TMAP1_HUMAN
θ value	1.06291 (rank : 70)	NC score	0.038671 (rank : 57)
Query Neighborhood Hits	164	Target Neighborhood Hits	140	Shared Neighborhood Hits	11
SwissProt Accessions	P84157	Gene names	TMAP1
Domain Architecture	No domain graphic available
Description	Transmembrane anchor protein 1.

ABCAD_HUMAN
θ value	1.38821 (rank : 71)	NC score	0.011094 (rank : 113)
Query Neighborhood Hits	164	Target Neighborhood Hits	207	Shared Neighborhood Hits	4
SwissProt Accessions	Q86UQ4, Q6ZTT7, Q86WI2, Q8N248	Gene names	ABCA13
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 13.

CM007_MOUSE
θ value	1.38821 (rank : 72)	NC score	0.022067 (rank : 82)
Query Neighborhood Hits	164	Target Neighborhood Hits	416	Shared Neighborhood Hits	10
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

RFIP3_HUMAN
θ value	1.38821 (rank : 73)	NC score	0.010904 (rank : 116)
Query Neighborhood Hits	164	Target Neighborhood Hits	1055	Shared Neighborhood Hits	30
SwissProt Accessions	O75154, Q4VXV7, Q9H155, Q9H1G0, Q9NUI0	Gene names	RAB11FIP3, KIAA0665
Domain Architecture
Description	Rab11 family-interacting protein 3 (Rab11-FIP3) (EF hands-containing Rab-interacting protein) (Eferin).

ZN358_HUMAN
θ value	1.38821 (rank : 74)	NC score	-0.002602 (rank : 165)
Query Neighborhood Hits	164	Target Neighborhood Hits	840	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NW07, Q9BTM7	Gene names	ZNF358
Domain Architecture
Description	Zinc finger protein 358.

EPC1_MOUSE
θ value	1.81305 (rank : 75)	NC score	0.013226 (rank : 107)
Query Neighborhood Hits	164	Target Neighborhood Hits	47	Shared Neighborhood Hits	2
SwissProt Accessions	Q8C9X6, Q9Z299	Gene names	Epc1
Domain Architecture	No domain graphic available
Description	Enhancer of polycomb homolog 1.

PROM1_MOUSE
θ value	1.81305 (rank : 76)	NC score	0.024752 (rank : 74)
Query Neighborhood Hits	164	Target Neighborhood Hits	77	Shared Neighborhood Hits	5
SwissProt Accessions	O54990, O35408	Gene names	Prom1, Prom, Proml1
Domain Architecture
Description	Prominin-1 precursor (Prominin-like protein 1) (Antigen AC133 homolog).

PRRT3_HUMAN
θ value	1.81305 (rank : 77)	NC score	0.031814 (rank : 60)
Query Neighborhood Hits	164	Target Neighborhood Hits	998	Shared Neighborhood Hits	68
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

WBP11_HUMAN
θ value	1.81305 (rank : 78)	NC score	0.030582 (rank : 62)
Query Neighborhood Hits	164	Target Neighborhood Hits	354	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

WBP11_MOUSE
θ value	1.81305 (rank : 79)	NC score	0.030352 (rank : 63)
Query Neighborhood Hits	164	Target Neighborhood Hits	362	Shared Neighborhood Hits	34
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

ZN409_HUMAN
θ value	1.81305 (rank : 80)	NC score	0.015337 (rank : 103)
Query Neighborhood Hits	164	Target Neighborhood Hits	842	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UPU6	Gene names	ZNF409, KIAA1056
Domain Architecture	No domain graphic available
Description	Zinc finger protein 409.

K1802_MOUSE
θ value	2.36792 (rank : 81)	NC score	0.023642 (rank : 77)
Query Neighborhood Hits	164	Target Neighborhood Hits	1596	Shared Neighborhood Hits	64
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

PABP2_HUMAN
θ value	2.36792 (rank : 82)	NC score	0.023739 (rank : 76)
Query Neighborhood Hits	164	Target Neighborhood Hits	212	Shared Neighborhood Hits	6
SwissProt Accessions	Q86U42, O43484	Gene names	PABPN1, PAB2, PABP2
Domain Architecture
Description	Polyadenylate-binding protein 2 (Poly(A)-binding protein 2) (Poly(A)- binding protein II) (PABII) (Polyadenylate-binding nuclear protein 1) (Nuclear poly(A)-binding protein 1).

PABP2_MOUSE
θ value	2.36792 (rank : 83)	NC score	0.023162 (rank : 78)
Query Neighborhood Hits	164	Target Neighborhood Hits	214	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CCS6, O35935	Gene names	Pabpn1, Pab2, Pabp2
Domain Architecture
Description	Polyadenylate-binding protein 2 (Poly(A)-binding protein 2) (Poly(A)- binding protein II) (PABII) (Polyadenylate-binding nuclear protein 1) (Nuclear poly(A)-binding protein 1).

PYGO2_HUMAN
θ value	2.36792 (rank : 84)	NC score	0.019497 (rank : 88)
Query Neighborhood Hits	164	Target Neighborhood Hits	189	Shared Neighborhood Hits	17
SwissProt Accessions	Q9BRQ0, Q8WYZ4, Q96CY2	Gene names	PYGO2
Domain Architecture
Description	Pygopus homolog 2.

ADDB_MOUSE
θ value	3.0926 (rank : 85)	NC score	0.013724 (rank : 105)
Query Neighborhood Hits	164	Target Neighborhood Hits	574	Shared Neighborhood Hits	27
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

ATBF1_HUMAN
θ value	3.0926 (rank : 86)	NC score	0.007065 (rank : 131)
Query Neighborhood Hits	164	Target Neighborhood Hits	1547	Shared Neighborhood Hits	36
SwissProt Accessions	Q15911, O15101, Q13719	Gene names	ATBF1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

BAI1_HUMAN
θ value	3.0926 (rank : 87)	NC score	0.004033 (rank : 153)
Query Neighborhood Hits	164	Target Neighborhood Hits	375	Shared Neighborhood Hits	21
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

COBA2_MOUSE
θ value	3.0926 (rank : 88)	NC score	0.010184 (rank : 120)
Query Neighborhood Hits	164	Target Neighborhood Hits	501	Shared Neighborhood Hits	33
SwissProt Accessions	Q64739, Q61432, Q9Z1W0	Gene names	Col11a2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

FOXL1_MOUSE
θ value	3.0926 (rank : 89)	NC score	0.010971 (rank : 115)
Query Neighborhood Hits	164	Target Neighborhood Hits	152	Shared Neighborhood Hits	11
SwissProt Accessions	Q64731	Gene names	Foxl1, Fkh6, Fkhl11
Domain Architecture
Description	Forkhead box protein L1 (Forkhead-related protein FKHL11) (Transcription factor FKH-6).

K1802_HUMAN
θ value	3.0926 (rank : 90)	NC score	0.015786 (rank : 98)
Query Neighborhood Hits	164	Target Neighborhood Hits	1378	Shared Neighborhood Hits	55
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

MTSS1_HUMAN
θ value	3.0926 (rank : 91)	NC score	0.016044 (rank : 97)
Query Neighborhood Hits	164	Target Neighborhood Hits	504	Shared Neighborhood Hits	31
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

PCLO_MOUSE
θ value	3.0926 (rank : 92)	NC score	0.018065 (rank : 93)
Query Neighborhood Hits	164	Target Neighborhood Hits	2275	Shared Neighborhood Hits	83
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

RERE_HUMAN
θ value	3.0926 (rank : 93)	NC score	0.015655 (rank : 99)
Query Neighborhood Hits	164	Target Neighborhood Hits	779	Shared Neighborhood Hits	40
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

TTK_MOUSE
θ value	3.0926 (rank : 94)	NC score	-0.002541 (rank : 164)
Query Neighborhood Hits	164	Target Neighborhood Hits	803	Shared Neighborhood Hits	6
SwissProt Accessions	P35761	Gene names	Ttk, Esk
Domain Architecture
Description	Dual specificity protein kinase TTK (EC 2.7.12.1) (ESK) (PYT).

WNK1_HUMAN
θ value	3.0926 (rank : 95)	NC score	-0.000991 (rank : 163)
Query Neighborhood Hits	164	Target Neighborhood Hits	1158	Shared Neighborhood Hits	35
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

BAG3_MOUSE
θ value	4.03905 (rank : 96)	NC score	0.019827 (rank : 87)
Query Neighborhood Hits	164	Target Neighborhood Hits	513	Shared Neighborhood Hits	44
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

CO4A1_MOUSE
θ value	4.03905 (rank : 97)	NC score	0.006868 (rank : 136)
Query Neighborhood Hits	164	Target Neighborhood Hits	450	Shared Neighborhood Hits	25
SwissProt Accessions	P02463	Gene names	Col4a1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

ERBB2_HUMAN
θ value	4.03905 (rank : 98)	NC score	-0.002798 (rank : 166)
Query Neighborhood Hits	164	Target Neighborhood Hits	1073	Shared Neighborhood Hits	22
SwissProt Accessions	P04626, Q14256, Q6LDV1, Q9UMK4	Gene names	ERBB2, HER2, NEU, NGL
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) (Tyrosine kinase-type cell surface receptor HER2) (MLN 19).

K1543_MOUSE
θ value	4.03905 (rank : 99)	NC score	0.024980 (rank : 73)
Query Neighborhood Hits	164	Target Neighborhood Hits	497	Shared Neighborhood Hits	33
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

LIPB2_MOUSE
θ value	4.03905 (rank : 100)	NC score	0.005493 (rank : 142)
Query Neighborhood Hits	164	Target Neighborhood Hits	570	Shared Neighborhood Hits	15
SwissProt Accessions	O35711, Q7TMG4, Q8CBS6, Q99KX6	Gene names	Ppfibp2, Cclp1
Domain Architecture
Description	Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2) (Coiled-coil-like protein 1).

PPRB_MOUSE
θ value	4.03905 (rank : 101)	NC score	0.018877 (rank : 89)
Query Neighborhood Hits	164	Target Neighborhood Hits	354	Shared Neighborhood Hits	26
SwissProt Accessions	Q925J9, O88323, Q3UHV0, Q6AXD5, Q8BW37, Q8BX19, Q8VDQ7, Q925K0	Gene names	Pparbp, Trip2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2).

RIN3_HUMAN
θ value	4.03905 (rank : 102)	NC score	0.016383 (rank : 96)
Query Neighborhood Hits	164	Target Neighborhood Hits	227	Shared Neighborhood Hits	23
SwissProt Accessions	Q8TB24, Q8NF30, Q8TEE8, Q8WYP4, Q9H6A5, Q9HAG1	Gene names	RIN3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

TRIPB_HUMAN
θ value	4.03905 (rank : 103)	NC score	0.002584 (rank : 156)
Query Neighborhood Hits	164	Target Neighborhood Hits	1587	Shared Neighborhood Hits	31
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

CD248_MOUSE
θ value	5.27518 (rank : 104)	NC score	0.005229 (rank : 143)
Query Neighborhood Hits	164	Target Neighborhood Hits	578	Shared Neighborhood Hits	28
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

COBA2_HUMAN
θ value	5.27518 (rank : 105)	NC score	0.009694 (rank : 123)
Query Neighborhood Hits	164	Target Neighborhood Hits	408	Shared Neighborhood Hits	22
SwissProt Accessions	P13942, Q07751, Q13271, Q13272, Q13273, Q99866, Q9UIP9	Gene names	COL11A2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

HHIP_HUMAN
θ value	5.27518 (rank : 106)	NC score	0.008650 (rank : 127)
Query Neighborhood Hits	164	Target Neighborhood Hits	249	Shared Neighborhood Hits	4
SwissProt Accessions	Q96QV1, Q6PK09, Q8NCI7, Q9BXK3, Q9H1J4, Q9H7E7	Gene names	HHIP, HIP
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

HHIP_MOUSE
θ value	5.27518 (rank : 107)	NC score	0.009232 (rank : 126)
Query Neighborhood Hits	164	Target Neighborhood Hits	219	Shared Neighborhood Hits	3
SwissProt Accessions	Q7TN16, Q8C0B0, Q9WU59	Gene names	Hhip, Hip
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

ISL2_HUMAN
θ value	5.27518 (rank : 108)	NC score	0.002868 (rank : 155)
Query Neighborhood Hits	164	Target Neighborhood Hits	435	Shared Neighborhood Hits	5
SwissProt Accessions	Q96A47	Gene names	ISL2
Domain Architecture
Description	Insulin gene enhancer protein ISL-2 (Islet-2).

K1543_HUMAN
θ value	5.27518 (rank : 109)	NC score	0.033010 (rank : 59)
Query Neighborhood Hits	164	Target Neighborhood Hits	435	Shared Neighborhood Hits	40
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

MRCKA_HUMAN
θ value	5.27518 (rank : 110)	NC score	-0.003153 (rank : 167)
Query Neighborhood Hits	164	Target Neighborhood Hits	1999	Shared Neighborhood Hits	31
SwissProt Accessions	Q5VT25, Q59GZ1, Q5H9N9, Q5T797, Q5VT26, Q5VT27, Q86XX2, Q86XX3, Q99646	Gene names	CDC42BPA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42- binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) (DMPK-like alpha).

PRP1_HUMAN
θ value	5.27518 (rank : 111)	NC score	0.022720 (rank : 80)
Query Neighborhood Hits	164	Target Neighborhood Hits	385	Shared Neighborhood Hits	38
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

TCOF_HUMAN
θ value	5.27518 (rank : 112)	NC score	0.020865 (rank : 86)
Query Neighborhood Hits	164	Target Neighborhood Hits	543	Shared Neighborhood Hits	25
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

YLPM1_HUMAN
θ value	5.27518 (rank : 113)	NC score	0.027688 (rank : 68)
Query Neighborhood Hits	164	Target Neighborhood Hits	670	Shared Neighborhood Hits	41
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

AP2A1_MOUSE
θ value	6.88961 (rank : 114)	NC score	0.006664 (rank : 137)
Query Neighborhood Hits	164	Target Neighborhood Hits	57	Shared Neighborhood Hits	6
SwissProt Accessions	P17426	Gene names	Ap2a1, Adtaa, Clapa1
Domain Architecture
Description	AP-2 complex subunit alpha-1 (Adapter-related protein complex 2 alpha- 1 subunit) (Alpha-adaptin A) (Adaptor protein complex AP-2 alpha-1 subunit) (Clathrin assembly protein complex 2 alpha-A large chain) (100 kDa coated vesicle protein A) (Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit).

ATBF1_MOUSE
θ value	6.88961 (rank : 115)	NC score	0.008589 (rank : 128)
Query Neighborhood Hits	164	Target Neighborhood Hits	1841	Shared Neighborhood Hits	48
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

BSN_MOUSE
θ value	6.88961 (rank : 116)	NC score	0.029030 (rank : 66)
Query Neighborhood Hits	164	Target Neighborhood Hits	2057	Shared Neighborhood Hits	83
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CC14B_HUMAN
θ value	6.88961 (rank : 117)	NC score	0.210831 (rank : 46)
Query Neighborhood Hits	164	Target Neighborhood Hits	114	Shared Neighborhood Hits	46
SwissProt Accessions	O60729, O43183, O60730	Gene names	CDC14B
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14B (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog B).

DIAP1_HUMAN
θ value	6.88961 (rank : 118)	NC score	0.007706 (rank : 130)
Query Neighborhood Hits	164	Target Neighborhood Hits	784	Shared Neighborhood Hits	41
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

DUET_HUMAN
θ value	6.88961 (rank : 119)	NC score	-0.004199 (rank : 169)
Query Neighborhood Hits	164	Target Neighborhood Hits	1220	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y2A5, Q8TBQ5, Q9NSZ4	Gene names	DUET, TRAD
Domain Architecture
Description	Serine/threonine-protein kinase Duet (EC 2.7.11.1) (Serine/threonine kinase with Dbl- and pleckstrin homology domain).

EFS_MOUSE
θ value	6.88961 (rank : 120)	NC score	0.015547 (rank : 100)
Query Neighborhood Hits	164	Target Neighborhood Hits	389	Shared Neighborhood Hits	30
SwissProt Accessions	Q64355	Gene names	Efs, Sin
Domain Architecture
Description	Embryonal Fyn-associated substrate (SRC-interacting protein) (Signal- integrating protein).

ELK4_MOUSE
θ value	6.88961 (rank : 121)	NC score	0.004251 (rank : 151)
Query Neighborhood Hits	164	Target Neighborhood Hits	107	Shared Neighborhood Hits	7
SwissProt Accessions	P41158	Gene names	Elk4, Sap1
Domain Architecture
Description	ETS domain-containing protein Elk-4 (Serum response factor accessory protein 1) (SAP-1).

K1958_HUMAN
θ value	6.88961 (rank : 122)	NC score	0.010211 (rank : 119)
Query Neighborhood Hits	164	Target Neighborhood Hits	76	Shared Neighborhood Hits	8
SwissProt Accessions	Q8N8K9, Q5T252, Q8TF43, Q96N02	Gene names	KIAA1958
Domain Architecture	No domain graphic available
Description	Protein KIAA1958.

MKL2_HUMAN
θ value	6.88961 (rank : 123)	NC score	0.010041 (rank : 121)
Query Neighborhood Hits	164	Target Neighborhood Hits	274	Shared Neighborhood Hits	19
SwissProt Accessions	Q9ULH7, Q68CT1, Q6UB16, Q86WW2, Q8N226	Gene names	MKL2, KIAA1243, MRTFB
Domain Architecture
Description	MKL/myocardin-like protein 2 (Myocardin-related transcription factor B) (MRTF-B) (Megakaryoblastic leukemia 2).

MLL2_HUMAN
θ value	6.88961 (rank : 124)	NC score	0.012097 (rank : 111)
Query Neighborhood Hits	164	Target Neighborhood Hits	1788	Shared Neighborhood Hits	63
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

MNT_HUMAN
θ value	6.88961 (rank : 125)	NC score	0.015343 (rank : 102)
Query Neighborhood Hits	164	Target Neighborhood Hits	496	Shared Neighborhood Hits	38
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

NELFA_HUMAN
θ value	6.88961 (rank : 126)	NC score	0.020994 (rank : 85)
Query Neighborhood Hits	164	Target Neighborhood Hits	161	Shared Neighborhood Hits	24
SwissProt Accessions	Q9H3P2, O95392	Gene names	WHSC2, NELFA
Domain Architecture	No domain graphic available
Description	Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 protein).

SETB1_MOUSE
θ value	6.88961 (rank : 127)	NC score	0.011167 (rank : 112)
Query Neighborhood Hits	164	Target Neighborhood Hits	150	Shared Neighborhood Hits	14
SwissProt Accessions	O88974, Q922K1	Gene names	Setdb1, Eset
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

SOX6_MOUSE
θ value	6.88961 (rank : 128)	NC score	0.004680 (rank : 146)
Query Neighborhood Hits	164	Target Neighborhood Hits	341	Shared Neighborhood Hits	17
SwissProt Accessions	P40645, Q62250, Q9QWS5	Gene names	Sox6, Sox-6
Domain Architecture
Description	Transcription factor SOX-6 (SOX-LZ).

STAT2_MOUSE
θ value	6.88961 (rank : 129)	NC score	0.005155 (rank : 144)
Query Neighborhood Hits	164	Target Neighborhood Hits	175	Shared Neighborhood Hits	13
SwissProt Accessions	Q9WVL2, Q64188, Q64189, Q64250	Gene names	Stat2
Domain Architecture
Description	Signal transducer and activator of transcription 2.

STX12_HUMAN
θ value	6.88961 (rank : 130)	NC score	0.004512 (rank : 149)
Query Neighborhood Hits	164	Target Neighborhood Hits	226	Shared Neighborhood Hits	4
SwissProt Accessions	Q86Y82, O95564	Gene names	STX12
Domain Architecture
Description	Syntaxin-12.

SYNE1_HUMAN
θ value	6.88961 (rank : 131)	NC score	0.006890 (rank : 135)
Query Neighborhood Hits	164	Target Neighborhood Hits	1484	Shared Neighborhood Hits	28
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

TOP2A_HUMAN
θ value	6.88961 (rank : 132)	NC score	0.005949 (rank : 139)
Query Neighborhood Hits	164	Target Neighborhood Hits	135	Shared Neighborhood Hits	6
SwissProt Accessions	P11388, Q71UN1, Q9HB24, Q9HB25, Q9HB26, Q9UP44, Q9UQP9	Gene names	TOP2A, TOP2
Domain Architecture
Description	DNA topoisomerase 2-alpha (EC 5.99.1.3) (DNA topoisomerase II, alpha isozyme).

TP4A1_HUMAN
θ value	6.88961 (rank : 133)	NC score	0.050604 (rank : 55)
Query Neighborhood Hits	164	Target Neighborhood Hits	68	Shared Neighborhood Hits	23
SwissProt Accessions	Q93096, O00648, Q49A54	Gene names	PTP4A1, PRL1, PTPCAAX1
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a1) (Protein-tyrosine phosphatase of regenerating liver 1) (PRL-1) (PTP(CAAXI)).

TP4A1_MOUSE
θ value	6.88961 (rank : 134)	NC score	0.050604 (rank : 56)
Query Neighborhood Hits	164	Target Neighborhood Hits	68	Shared Neighborhood Hits	23
SwissProt Accessions	Q63739, O09097, O09154, Q3UFU9	Gene names	Ptp4a1, Prl1
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a1) (Protein-tyrosine phosphatase of regenerating liver 1) (PRL-1).

UBF1_HUMAN
θ value	6.88961 (rank : 135)	NC score	0.004618 (rank : 148)
Query Neighborhood Hits	164	Target Neighborhood Hits	415	Shared Neighborhood Hits	7
SwissProt Accessions	P17480	Gene names	UBTF, UBF, UBF1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1) (Autoantigen NOR-90).

AKAP2_MOUSE
θ value	8.99809 (rank : 136)	NC score	0.012294 (rank : 109)
Query Neighborhood Hits	164	Target Neighborhood Hits	385	Shared Neighborhood Hits	24
SwissProt Accessions	O54931, O54932, O54933	Gene names	Akap2
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2) (AKAP expressed in kidney and lung) (AKAP-KL).

AMPH_HUMAN
θ value	8.99809 (rank : 137)	NC score	0.009755 (rank : 122)
Query Neighborhood Hits	164	Target Neighborhood Hits	455	Shared Neighborhood Hits	27
SwissProt Accessions	P49418, O43538, Q75MJ8, Q75MK5, Q75MM3, Q8N4G0	Gene names	AMPH, AMPH1
Domain Architecture
Description	Amphiphysin.

AP2A1_HUMAN
θ value	8.99809 (rank : 138)	NC score	0.006962 (rank : 134)
Query Neighborhood Hits	164	Target Neighborhood Hits	56	Shared Neighborhood Hits	5
SwissProt Accessions	O95782, Q96CI7, Q96PP6, Q96PP7, Q9H070	Gene names	AP2A1, ADTAA
Domain Architecture
Description	AP-2 complex subunit alpha-1 (Adapter-related protein complex 2 alpha- 1 subunit) (Alpha-adaptin A) (Adaptor protein complex AP-2 alpha-1 subunit) (Clathrin assembly protein complex 2 alpha-A large chain) (100 kDa coated vesicle protein A) (Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit).

BSN_HUMAN
θ value	8.99809 (rank : 139)	NC score	0.018313 (rank : 91)
Query Neighborhood Hits	164	Target Neighborhood Hits	1537	Shared Neighborhood Hits	70
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

CO5A1_HUMAN
θ value	8.99809 (rank : 140)	NC score	0.010708 (rank : 117)
Query Neighborhood Hits	164	Target Neighborhood Hits	434	Shared Neighborhood Hits	27
SwissProt Accessions	P20908, Q15094, Q5SUX4	Gene names	COL5A1
Domain Architecture
Description	Collagen alpha-1(V) chain precursor.

CO5A1_MOUSE
θ value	8.99809 (rank : 141)	NC score	0.010366 (rank : 118)
Query Neighborhood Hits	164	Target Neighborhood Hits	419	Shared Neighborhood Hits	25
SwissProt Accessions	O88207	Gene names	Col5a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(V) chain precursor.

CSKI1_HUMAN
θ value	8.99809 (rank : 142)	NC score	0.005778 (rank : 141)
Query Neighborhood Hits	164	Target Neighborhood Hits	997	Shared Neighborhood Hits	46
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

EFS_HUMAN
θ value	8.99809 (rank : 143)	NC score	0.013344 (rank : 106)
Query Neighborhood Hits	164	Target Neighborhood Hits	348	Shared Neighborhood Hits	26
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

FOXK2_HUMAN
θ value	8.99809 (rank : 144)	NC score	0.004747 (rank : 145)
Query Neighborhood Hits	164	Target Neighborhood Hits	190	Shared Neighborhood Hits	9
SwissProt Accessions	Q01167, Q13622, Q13623, Q13624	Gene names	FOXK2, ILF, ILF1
Domain Architecture
Description	Forkhead box protein K2 (Interleukin enhancer-binding factor 1) (Cellular transcription factor ILF-1).

HTF4_MOUSE
θ value	8.99809 (rank : 145)	NC score	0.005847 (rank : 140)
Query Neighborhood Hits	164	Target Neighborhood Hits	153	Shared Neighborhood Hits	8
SwissProt Accessions	Q61286	Gene names	Tcf12, Alf1, Meb
Domain Architecture
Description	Transcription factor 12 (Transcription factor HTF-4) (E-box-binding protein) (DNA-binding protein HTF4) (Class A helix-loop-helix transcription factor ME1).

MCL1_MOUSE
θ value	8.99809 (rank : 146)	NC score	0.006989 (rank : 133)
Query Neighborhood Hits	164	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	P97287, Q3TUS0, Q792P0, Q9CRI4	Gene names	Mcl1
Domain Architecture	No domain graphic available
Description	Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Bcl-2-related protein EAT/mcl1).

MUCDL_HUMAN
θ value	8.99809 (rank : 147)	NC score	0.012726 (rank : 108)
Query Neighborhood Hits	164	Target Neighborhood Hits	777	Shared Neighborhood Hits	48
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

MYO15_HUMAN
θ value	8.99809 (rank : 148)	NC score	0.004176 (rank : 152)
Query Neighborhood Hits	164	Target Neighborhood Hits	671	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

NARGL_MOUSE
θ value	8.99809 (rank : 149)	NC score	0.004671 (rank : 147)
Query Neighborhood Hits	164	Target Neighborhood Hits	175	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DBB4, Q3U7V2	Gene names	Narg1l, Nat2
Domain Architecture	No domain graphic available
Description	NMDA receptor-regulated 1-like protein (NARG1-like protein).

NCOA2_MOUSE
θ value	8.99809 (rank : 150)	NC score	0.006309 (rank : 138)
Query Neighborhood Hits	164	Target Neighborhood Hits	281	Shared Neighborhood Hits	22
SwissProt Accessions	Q61026, O09001, P97759	Gene names	Ncoa2, Grip1, Tif2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2) (Glucocorticoid receptor-interacting protein 1) (GRIP-1).

NCOA6_HUMAN
θ value	8.99809 (rank : 151)	NC score	0.017940 (rank : 94)
Query Neighborhood Hits	164	Target Neighborhood Hits	1202	Shared Neighborhood Hits	63
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

NCOR1_HUMAN
θ value	8.99809 (rank : 152)	NC score	0.008063 (rank : 129)
Query Neighborhood Hits	164	Target Neighborhood Hits	577	Shared Neighborhood Hits	29
SwissProt Accessions	O75376, Q9UPV5, Q9UQ18	Gene names	NCOR1, KIAA1047
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR).

NELFA_MOUSE
θ value	8.99809 (rank : 153)	NC score	0.018124 (rank : 92)
Query Neighborhood Hits	164	Target Neighborhood Hits	195	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BG30, Q8BVE4, Q8VEI7, Q9CSJ9, Q9Z1V9	Gene names	Whsc2, Nelfa, Whsc2h
Domain Architecture	No domain graphic available
Description	Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 homolog) (mWHSC2).

NR4A2_HUMAN
θ value	8.99809 (rank : 154)	NC score	0.001249 (rank : 160)
Query Neighborhood Hits	164	Target Neighborhood Hits	120	Shared Neighborhood Hits	4
SwissProt Accessions	P43354, Q16311	Gene names	NR4A2, NOT, NURR1, TINUR
Domain Architecture
Description	Orphan nuclear receptor NR4A2 (Orphan nuclear receptor NURR1) (Immediate-early response protein NOT) (Transcriptionally-inducible nuclear receptor).

NR4A2_MOUSE
θ value	8.99809 (rank : 155)	NC score	0.001250 (rank : 159)
Query Neighborhood Hits	164	Target Neighborhood Hits	121	Shared Neighborhood Hits	4
SwissProt Accessions	Q06219, O08690	Gene names	Nr4a2, Nurr1
Domain Architecture
Description	Orphan nuclear receptor NR4A2 (Orphan nuclear receptor NURR1) (NUR- related factor 1).

OSBL5_MOUSE
θ value	8.99809 (rank : 156)	NC score	0.003989 (rank : 154)
Query Neighborhood Hits	164	Target Neighborhood Hits	77	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ER64, Q8R510, Q99NF5	Gene names	Osbpl5, Obph1, Osbp2
Domain Architecture
Description	Oxysterol-binding protein-related protein 5 (OSBP-related protein 5) (ORP-5) (Oxysterol-binding protein homolog 1).

PRDM2_HUMAN
θ value	8.99809 (rank : 157)	NC score	0.000165 (rank : 161)
Query Neighborhood Hits	164	Target Neighborhood Hits	1135	Shared Neighborhood Hits	32
SwissProt Accessions	Q13029, Q13149, Q14550, Q5VUL9	Gene names	PRDM2, RIZ
Domain Architecture
Description	PR domain zinc finger protein 2 (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc-finger protein) (Zinc finger protein RIZ) (MTE-binding protein) (MTB-ZF) (GATA-3-binding protein G3B).

PRR12_HUMAN
θ value	8.99809 (rank : 158)	NC score	0.021795 (rank : 83)
Query Neighborhood Hits	164	Target Neighborhood Hits	460	Shared Neighborhood Hits	41
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

SRRM2_MOUSE
θ value	8.99809 (rank : 159)	NC score	0.024307 (rank : 75)
Query Neighborhood Hits	164	Target Neighborhood Hits	1470	Shared Neighborhood Hits	61
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

STAP2_MOUSE
θ value	8.99809 (rank : 160)	NC score	0.011077 (rank : 114)
Query Neighborhood Hits	164	Target Neighborhood Hits	41	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R0L1, Q8BWS2	Gene names	Stap2
Domain Architecture	No domain graphic available
Description	Signal-transducing adaptor protein 2 (STAP-2).

TBCD4_HUMAN
θ value	8.99809 (rank : 161)	NC score	0.004264 (rank : 150)
Query Neighborhood Hits	164	Target Neighborhood Hits	357	Shared Neighborhood Hits	8
SwissProt Accessions	O60343, Q5W0B9	Gene names	TBC1D4, KIAA0603
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 4 (Akt substrate of 160 kDa) (AS160).

TNR6A_HUMAN
θ value	8.99809 (rank : 162)	NC score	0.009456 (rank : 124)
Query Neighborhood Hits	164	Target Neighborhood Hits	343	Shared Neighborhood Hits	21
SwissProt Accessions	Q8NDV7, O15408, Q658L5, Q6NVB5, Q8NEZ0, Q8TBT8, Q8TCR0, Q9NV59, Q9P268	Gene names	TNRC6A, CAGH26, KIAA1460, TNRC6
Domain Architecture	No domain graphic available
Description	Trinucleotide repeat-containing gene 6A protein (CAG repeat protein 26) (Glycine-tryptophan protein of 182 kDa) (GW182 autoantigen) (Protein GW1) (EMSY interactor protein).

VITRN_MOUSE
θ value	8.99809 (rank : 163)	NC score	0.002511 (rank : 157)
Query Neighborhood Hits	164	Target Neighborhood Hits	68	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VHI5, Q3TZ47, Q8BQ41, Q8K047, Q9CYZ1	Gene names	Vit
Domain Architecture	No domain graphic available
Description	Vitrin precursor.

ZXDB_HUMAN
θ value	8.99809 (rank : 164)	NC score	-0.003570 (rank : 168)
Query Neighborhood Hits	164	Target Neighborhood Hits	753	Shared Neighborhood Hits	12
SwissProt Accessions	P98169, Q9UBB3	Gene names	ZXDB
Domain Architecture	No domain graphic available
Description	Zinc finger X-linked protein ZXDB.

CC14B_MOUSE
θ value	θ > 10 (rank : 165)	NC score	0.171463 (rank : 51)
Query Neighborhood Hits	164	Target Neighborhood Hits	103	Shared Neighborhood Hits	40
SwissProt Accessions	Q6PFY9, Q80WC4, Q8BLV5	Gene names	Cdc14b
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14B (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog B).

DUS23_HUMAN
θ value	θ > 10 (rank : 166)	NC score	0.194649 (rank : 48)
Query Neighborhood Hits	164	Target Neighborhood Hits	98	Shared Neighborhood Hits	35
SwissProt Accessions	Q9BVJ7, Q9NX48	Gene names	DUSP23, LDP3, VHZ
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 23 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular mass dual specificity phosphatase 3) (LDP-3) (VH1-like phosphatase Z).

DUS23_MOUSE
θ value	θ > 10 (rank : 167)	NC score	0.174217 (rank : 50)
Query Neighborhood Hits	164	Target Neighborhood Hits	94	Shared Neighborhood Hits	33
SwissProt Accessions	Q6NT99, Q9CW48	Gene names	Dusp23, Ldp3
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 23 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular mass dual specificity phosphatase 3) (LDP-3).

TP4A3_HUMAN
θ value	θ > 10 (rank : 168)	NC score	0.062104 (rank : 52)
Query Neighborhood Hits	164	Target Neighborhood Hits	62	Shared Neighborhood Hits	27
SwissProt Accessions	O75365, Q8IVN5, Q99849, Q9BTW5	Gene names	PTP4A3, PRL3
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a3) (Protein-tyrosine phosphatase of regenerating liver 3) (PRL-3) (PRL-R).

TP4A3_MOUSE
θ value	θ > 10 (rank : 169)	NC score	0.059323 (rank : 53)
Query Neighborhood Hits	164	Target Neighborhood Hits	60	Shared Neighborhood Hits	27
SwissProt Accessions	Q9D658, O70275, Q3T9Z5, Q9CTC8	Gene names	Ptp4a3, Prl3
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a3) (Protein-tyrosine phosphatase of regenerating liver 3) (PRL-3).

Hits sorted by NC score

SSH1_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	164	Target Neighborhood Hits	164	Shared Neighborhood Hits	164
SwissProt Accessions	Q8WYL5, Q6P6C0, Q8N9A7, Q8WYL3, Q8WYL4, Q9P2P8	Gene names	SSH1, KIAA1298, SSH1L
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 1 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-1L) (hSSH-1L).

SSH1_MOUSE
NC score	0.989644 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	164	Target Neighborhood Hits	107	Shared Neighborhood Hits	63
SwissProt Accessions	Q76I79, Q3TDG3, Q69ZM4, Q811E5	Gene names	Ssh1, Kiaa1298, Ssh1l
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 1 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-1L) (mSSH-1L).

SSH2_MOUSE
NC score	0.965279 (rank : 3)	θ value	0 (rank : 4)
Query Neighborhood Hits	164	Target Neighborhood Hits	119	Shared Neighborhood Hits	51
SwissProt Accessions	Q5SW75, Q3TDK8, Q3TYP8, Q3U2K3, Q5F268, Q5SW74, Q69ZC3, Q76I78	Gene names	Ssh2, Kiaa1725, Ssh2l
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 2 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-2L) (mSSH-2L).

SSH3_MOUSE
NC score	0.963383 (rank : 4)	θ value	5.61992e-127 (rank : 5)
Query Neighborhood Hits	164	Target Neighborhood Hits	69	Shared Neighborhood Hits	49
SwissProt Accessions	Q8K330, Q3UDX0	Gene names	Ssh3, Ssh3l
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 3 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-3L) (mSSH-3L).

SSH2_HUMAN
NC score	0.962722 (rank : 5)	θ value	0 (rank : 3)
Query Neighborhood Hits	164	Target Neighborhood Hits	140	Shared Neighborhood Hits	53
SwissProt Accessions	Q76I76, Q8TDB5, Q8WYL1, Q8WYL2, Q96F40, Q96H36, Q9C0D8	Gene names	SSH2, KIAA1725, SSH2L
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 2 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-2L) (hSSH-2L).

SSH3_HUMAN
NC score	0.960700 (rank : 6)	θ value	3.52827e-121 (rank : 6)
Query Neighborhood Hits	164	Target Neighborhood Hits	75	Shared Neighborhood Hits	49
SwissProt Accessions	Q8TE77, Q6PK42, Q76I75, Q8N9L8, Q8WYL0, Q9NV45, Q9NWZ7	Gene names	SSH3, SSH3L
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 3 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-3L) (hSSH-3L).

DUS19_HUMAN
NC score	0.830068 (rank : 7)	θ value	6.62687e-19 (rank : 21)
Query Neighborhood Hits	164	Target Neighborhood Hits	52	Shared Neighborhood Hits	48
SwissProt Accessions	Q8WTR2, Q8WYN4	Gene names	DUSP19, DUSP17, SKRP1
Domain Architecture
Description	Dual specificity protein phosphatase 19 (EC 3.1.3.48) (EC 3.1.3.16) (Stress-activated protein kinase pathway-regulating phosphatase 1) (Protein phosphatase SKRP1).

DUS19_MOUSE
NC score	0.828316 (rank : 8)	θ value	4.74913e-17 (rank : 26)
Query Neighborhood Hits	164	Target Neighborhood Hits	58	Shared Neighborhood Hits	48
SwissProt Accessions	Q8K4T5	Gene names	Dusp19, Skrp1
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 19 (EC 3.1.3.48) (EC 3.1.3.16) (Stress-activated protein kinase pathway-regulating phosphatase 1) (Protein phosphatase SKRP1).

DUS9_HUMAN
NC score	0.813717 (rank : 9)	θ value	3.75424e-22 (rank : 9)
Query Neighborhood Hits	164	Target Neighborhood Hits	59	Shared Neighborhood Hits	48
SwissProt Accessions	Q99956	Gene names	DUSP9, MKP4
Domain Architecture
Description	Dual specificity protein phosphatase 9 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 4) (MAP kinase phosphatase 4) (MKP-4).

DUS2_HUMAN
NC score	0.806299 (rank : 10)	θ value	9.87957e-23 (rank : 7)
Query Neighborhood Hits	164	Target Neighborhood Hits	67	Shared Neighborhood Hits	48
SwissProt Accessions	Q05923	Gene names	DUSP2, PAC1
Domain Architecture
Description	Dual specificity protein phosphatase 2 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase PAC-1).

DUS2_MOUSE
NC score	0.806252 (rank : 11)	θ value	9.87957e-23 (rank : 8)
Query Neighborhood Hits	164	Target Neighborhood Hits	86	Shared Neighborhood Hits	51
SwissProt Accessions	Q05922, Q60640	Gene names	Dusp2, Pac-1, Pac1
Domain Architecture
Description	Dual specificity protein phosphatase 2 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase PAC-1).

STYX_MOUSE
NC score	0.806080 (rank : 12)	θ value	8.95645e-16 (rank : 29)
Query Neighborhood Hits	164	Target Neighborhood Hits	62	Shared Neighborhood Hits	49
SwissProt Accessions	Q60969, Q3TMA3, Q60970, Q9DCF8	Gene names	Styx
Domain Architecture
Description	Serine/threonine/tyrosine-interacting protein (Protein tyrosine phosphatase-like protein) (Phosphoserine/threonine/tyrosine interaction protein).

DUS22_MOUSE
NC score	0.805437 (rank : 13)	θ value	6.85773e-16 (rank : 28)
Query Neighborhood Hits	164	Target Neighborhood Hits	57	Shared Neighborhood Hits	50
SwissProt Accessions	Q99N11, Q5SQN9, Q5SQP0	Gene names	Dusp22
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 22 (EC 3.1.3.48) (EC 3.1.3.16) (LMW-DSP2).

DUS22_HUMAN
NC score	0.805401 (rank : 14)	θ value	5.25075e-16 (rank : 27)
Query Neighborhood Hits	164	Target Neighborhood Hits	58	Shared Neighborhood Hits	50
SwissProt Accessions	Q9NRW4, Q59GW2, Q5VWR2, Q96AR1	Gene names	DUSP22, JSP1, MKPX
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 22 (EC 3.1.3.48) (EC 3.1.3.16) (JNK-stimulatory phosphatase-1) (JSP-1) (Mitogen-activated protein kinase phosphatase x) (LMW-DSP2).

STYX_HUMAN
NC score	0.804827 (rank : 15)	θ value	4.44505e-15 (rank : 30)
Query Neighborhood Hits	164	Target Neighborhood Hits	60	Shared Neighborhood Hits	50
SwissProt Accessions	Q8WUJ0, Q99850	Gene names	STYX
Domain Architecture
Description	Serine/threonine/tyrosine-interacting protein (Protein tyrosine phosphatase-like protein).

DUS5_HUMAN
NC score	0.802236 (rank : 16)	θ value	3.17815e-21 (rank : 13)
Query Neighborhood Hits	164	Target Neighborhood Hits	82	Shared Neighborhood Hits	50
SwissProt Accessions	Q16690, Q12997	Gene names	DUSP5, VH3
Domain Architecture
Description	Dual specificity protein phosphatase 5 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase hVH3).

DUS14_MOUSE
NC score	0.799373 (rank : 17)	θ value	1.13037e-18 (rank : 23)
Query Neighborhood Hits	164	Target Neighborhood Hits	67	Shared Neighborhood Hits	48
SwissProt Accessions	Q9JLY7, Q9D715	Gene names	Dusp14, Mkp6
Domain Architecture
Description	Dual specificity protein phosphatase 14 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 6) (MAP kinase phosphatase 6) (MKP-6).

DUS14_HUMAN
NC score	0.796504 (rank : 18)	θ value	1.13037e-18 (rank : 22)
Query Neighborhood Hits	164	Target Neighborhood Hits	64	Shared Neighborhood Hits	47
SwissProt Accessions	O95147	Gene names	DUSP14, MKP6
Domain Architecture
Description	Dual specificity protein phosphatase 14 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 6) (MAP kinase phosphatase 6) (MKP-6) (MKP-1-like protein tyrosine phosphatase) (MKP- L).

DUS10_MOUSE
NC score	0.795352 (rank : 19)	θ value	1.2077e-20 (rank : 18)
Query Neighborhood Hits	164	Target Neighborhood Hits	62	Shared Neighborhood Hits	48
SwissProt Accessions	Q9ESS0, Q9CZY9	Gene names	Dusp10, Mkp5
Domain Architecture
Description	Dual specificity protein phosphatase 10 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 5) (MAP kinase phosphatase 5) (MKP-5).

DUS10_HUMAN
NC score	0.794348 (rank : 20)	θ value	1.2077e-20 (rank : 17)
Query Neighborhood Hits	164	Target Neighborhood Hits	64	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y6W6	Gene names	DUSP10, MKP5
Domain Architecture
Description	Dual specificity protein phosphatase 10 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 5) (MAP kinase phosphatase 5) (MKP-5).

DUS15_HUMAN
NC score	0.788489 (rank : 21)	θ value	7.09661e-13 (rank : 31)
Query Neighborhood Hits	164	Target Neighborhood Hits	60	Shared Neighborhood Hits	49
SwissProt Accessions	Q9H1R2, Q5QP62, Q5QP63, Q5QP65, Q6PGN7, Q8N826, Q9BX24	Gene names	DUSP15, C20orf57, VHY
Domain Architecture
Description	Dual specificity protein phosphatase 15 (EC 3.1.3.48) (EC 3.1.3.16) (Vaccinia virus VH1-related dual-specific protein phosphatase Y) (VH1- related member Y).

DUS1_HUMAN
NC score	0.787749 (rank : 22)	θ value	8.36355e-22 (rank : 10)
Query Neighborhood Hits	164	Target Neighborhood Hits	73	Shared Neighborhood Hits	50
SwissProt Accessions	P28562, Q2V508	Gene names	DUSP1, CL100, MKP1, PTPN10, VH1
Domain Architecture
Description	Dual specificity protein phosphatase 1 (EC 3.1.3.48) (EC 3.1.3.16) (MAP kinase phosphatase 1) (MKP-1) (Protein-tyrosine phosphatase CL100) (Dual specificity protein phosphatase hVH1).

DUS7_HUMAN
NC score	0.787503 (rank : 23)	θ value	9.24701e-21 (rank : 16)
Query Neighborhood Hits	164	Target Neighborhood Hits	69	Shared Neighborhood Hits	50
SwissProt Accessions	Q16829, Q8NFJ0	Gene names	DUSP7, PYST2
Domain Architecture
Description	Dual specificity protein phosphatase 7 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase PYST2).

DUS6_HUMAN
NC score	0.787240 (rank : 24)	θ value	3.17815e-21 (rank : 14)
Query Neighborhood Hits	164	Target Neighborhood Hits	57	Shared Neighborhood Hits	46
SwissProt Accessions	Q16828, O75109, Q53Y75, Q9BSH6	Gene names	DUSP6, MKP3, PYST1
Domain Architecture
Description	Dual specificity protein phosphatase 6 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 3) (MAP kinase phosphatase 3) (MKP-3) (Dual specificity protein phosphatase PYST1).

DUS6_MOUSE
NC score	0.785869 (rank : 25)	θ value	1.2077e-20 (rank : 19)
Query Neighborhood Hits	164	Target Neighborhood Hits	57	Shared Neighborhood Hits	46
SwissProt Accessions	Q9DBB1, Q542I5, Q9D7L4	Gene names	Dusp6, Mkp3
Domain Architecture
Description	Dual specificity protein phosphatase 6 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 3) (MAP kinase phosphatase 3) (MKP-3).

DUS1_MOUSE
NC score	0.784427 (rank : 26)	θ value	1.09232e-21 (rank : 11)
Query Neighborhood Hits	164	Target Neighborhood Hits	72	Shared Neighborhood Hits	50
SwissProt Accessions	P28563	Gene names	Dusp1, 3ch134, Mkp1, Ptpn10, Ptpn16
Domain Architecture
Description	Dual specificity protein phosphatase 1 (EC 3.1.3.48) (EC 3.1.3.16) (MAP kinase phosphatase 1) (MKP-1) (Protein-tyrosine phosphatase 3CH134) (Protein-tyrosine phosphatase ERP).

DUS4_HUMAN
NC score	0.781771 (rank : 27)	θ value	1.42661e-21 (rank : 12)
Query Neighborhood Hits	164	Target Neighborhood Hits	77	Shared Neighborhood Hits	48
SwissProt Accessions	Q13115, Q13524	Gene names	DUSP4, MKP2, VH2
Domain Architecture
Description	Dual specificity protein phosphatase 4 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 2) (MAP kinase phosphatase 2) (MKP-2) (Dual specificity protein phosphatase hVH2).

DUS4_MOUSE
NC score	0.780882 (rank : 28)	θ value	9.24701e-21 (rank : 15)
Query Neighborhood Hits	164	Target Neighborhood Hits	75	Shared Neighborhood Hits	48
SwissProt Accessions	Q8BFV3	Gene names	Dusp4
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 4 (EC 3.1.3.48) (EC 3.1.3.16).

DUS16_HUMAN
NC score	0.775344 (rank : 29)	θ value	5.60996e-18 (rank : 25)
Query Neighborhood Hits	164	Target Neighborhood Hits	112	Shared Neighborhood Hits	55
SwissProt Accessions	Q9BY84, Q9C0G3	Gene names	DUSP16, KIAA1700, MKP7
Domain Architecture
Description	Dual specificity protein phosphatase 16 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 7) (MAP kinase phosphatase 7) (MKP-7).

DUS8_MOUSE
NC score	0.767827 (rank : 30)	θ value	1.92812e-18 (rank : 24)
Query Neighborhood Hits	164	Target Neighborhood Hits	119	Shared Neighborhood Hits	56
SwissProt Accessions	O09112	Gene names	Dusp8, Nttp1
Domain Architecture
Description	Dual specificity protein phosphatase 8 (EC 3.1.3.48) (EC 3.1.3.16) (Neuronal tyrosine threonine phosphatase 1).

DUS8_HUMAN
NC score	0.762828 (rank : 31)	θ value	5.07402e-19 (rank : 20)
Query Neighborhood Hits	164	Target Neighborhood Hits	161	Shared Neighborhood Hits	61
SwissProt Accessions	Q13202	Gene names	DUSP8, VH5
Domain Architecture
Description	Dual specificity protein phosphatase 8 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase hVH-5).

DUS18_MOUSE
NC score	0.762402 (rank : 32)	θ value	4.59992e-12 (rank : 33)
Query Neighborhood Hits	164	Target Neighborhood Hits	53	Shared Neighborhood Hits	47
SwissProt Accessions	Q8VE01	Gene names	Dusp18
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 18 (EC 3.1.3.48) (EC 3.1.3.16).

DUS21_HUMAN
NC score	0.761599 (rank : 33)	θ value	2.98157e-11 (rank : 36)
Query Neighborhood Hits	164	Target Neighborhood Hits	52	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H596, Q6IAJ6, Q6YDQ8	Gene names	DUSP21, LMWDSP21
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 21 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular weight dual specificity phosphatase 21).

DUS18_HUMAN
NC score	0.761397 (rank : 34)	θ value	3.52202e-12 (rank : 32)
Query Neighborhood Hits	164	Target Neighborhood Hits	52	Shared Neighborhood Hits	47
SwissProt Accessions	Q8NEJ0	Gene names	DUSP18, LMWDSP20
Domain Architecture
Description	Dual specificity protein phosphatase 18 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular weight dual specificity phosphatase 20).

DUS3_HUMAN
NC score	0.751406 (rank : 35)	θ value	9.59137e-10 (rank : 37)
Query Neighborhood Hits	164	Target Neighborhood Hits	58	Shared Neighborhood Hits	46
SwissProt Accessions	P51452	Gene names	DUSP3, VHR
Domain Architecture
Description	Dual specificity protein phosphatase 3 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase VHR).

DUS3_MOUSE
NC score	0.750756 (rank : 36)	θ value	1.63604e-09 (rank : 38)
Query Neighborhood Hits	164	Target Neighborhood Hits	54	Shared Neighborhood Hits	46
SwissProt Accessions	Q9D7X3	Gene names	Dusp3
Domain Architecture
Description	Dual specificity protein phosphatase 3 (EC 3.1.3.48) (EC 3.1.3.16) (T- DSP11).

DUS13_MOUSE
NC score	0.740569 (rank : 37)	θ value	2.13673e-09 (rank : 39)
Query Neighborhood Hits	164	Target Neighborhood Hits	56	Shared Neighborhood Hits	47
SwissProt Accessions	Q9QYJ7	Gene names	Dusp13, Tmdp
Domain Architecture
Description	Dual specificity protein phosphatase 13 (EC 3.1.3.48) (EC 3.1.3.16) (Testis- and skeletal muscle-specific DSP) (Dual specificity tyrosine phosphatase TS-DSP6).

DUS12_MOUSE
NC score	0.737033 (rank : 38)	θ value	1.33837e-11 (rank : 34)
Query Neighborhood Hits	164	Target Neighborhood Hits	60	Shared Neighborhood Hits	48
SwissProt Accessions	Q9D0T2, Q9EQD3	Gene names	Dusp12
Domain Architecture
Description	Dual specificity protein phosphatase 12 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity phosphatase T-DSP4) (Dual specificity phosphatase VH1).

DUS13_HUMAN
NC score	0.732832 (rank : 39)	θ value	1.38499e-08 (rank : 40)
Query Neighborhood Hits	164	Target Neighborhood Hits	59	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UII6, Q5JSC6, Q96GC2	Gene names	DUSP13, TMDP
Domain Architecture
Description	Dual specificity protein phosphatase 13 (EC 3.1.3.48) (EC 3.1.3.16) (Testis- and skeletal-muscle-specific DSP) (Dual specificity phosphatase SKRP4).

DUS12_HUMAN
NC score	0.731019 (rank : 40)	θ value	2.98157e-11 (rank : 35)
Query Neighborhood Hits	164	Target Neighborhood Hits	60	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UNI6	Gene names	DUSP12
Domain Architecture
Description	Dual specificity protein phosphatase 12 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity tyrosine phosphatase YVH1).

STYL1_HUMAN
NC score	0.717371 (rank : 41)	θ value	1.69304e-06 (rank : 41)
Query Neighborhood Hits	164	Target Neighborhood Hits	43	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Y6J8, Q9UBP1, Q9UK06, Q9UK07, Q9UKG2, Q9UKG3	Gene names	STYXL1, DUSP24, MKSTYX
Domain Architecture
Description	Serine/threonine/tyrosine-interacting-like protein 1 (Dual specificity protein phosphatase 24) (Map kinase phosphatase-like protein MK-STYX) (Dual specificity phosphatase inhibitor MK-STYX).

PTPM1_MOUSE
NC score	0.454689 (rank : 42)	θ value	0.0736092 (rank : 45)
Query Neighborhood Hits	164	Target Neighborhood Hits	64	Shared Neighborhood Hits	48
SwissProt Accessions	Q66GT5, Q9CSJ8, Q9D622	Gene names	Ptpmt1, Plip
Domain Architecture	No domain graphic available
Description	Protein-tyrosine phosphatase mitochondrial 1, mitochondrial precursor (EC 3.1.3.48) (EC 3.1.3.16) (PTEN-like phosphatase) (Phosphoinositide lipid phosphatase).

PTPM1_HUMAN
NC score	0.431434 (rank : 43)	θ value	0.0431538 (rank : 44)
Query Neighborhood Hits	164	Target Neighborhood Hits	60	Shared Neighborhood Hits	47
SwissProt Accessions	Q8WUK0, Q7Z557, Q96CR2, Q9BXV8	Gene names	PTPMT1, MOSP, PLIP
Domain Architecture	No domain graphic available
Description	Protein-tyrosine phosphatase mitochondrial 1, mitochondrial precursor (EC 3.1.3.48) (EC 3.1.3.16) (PTEN-like phosphatase) (Phosphoinositide lipid phosphatase).

EPM2A_MOUSE
NC score	0.255854 (rank : 44)	θ value	0.813845 (rank : 58)
Query Neighborhood Hits	164	Target Neighborhood Hits	47	Shared Neighborhood Hits	37
SwissProt Accessions	Q9WUA5, Q8BY80	Gene names	Epm2a
Domain Architecture	No domain graphic available
Description	Laforin (EC 3.1.3.48) (EC 3.1.3.16) (Lafora PTPase) (LAFPTPase).

EPM2A_HUMAN
NC score	0.244313 (rank : 45)	θ value	1.06291 (rank : 63)
Query Neighborhood Hits	164	Target Neighborhood Hits	47	Shared Neighborhood Hits	38
SwissProt Accessions	O95278, O95483, Q8IU96, Q8IX24, Q8IX25, Q9BS66, Q9UEN2	Gene names	EPM2A
Domain Architecture	No domain graphic available
Description	Laforin (EC 3.1.3.48) (EC 3.1.3.16) (Lafora PTPase) (LAFPTPase).

CC14B_HUMAN
NC score	0.210831 (rank : 46)	θ value	6.88961 (rank : 117)
Query Neighborhood Hits	164	Target Neighborhood Hits	114	Shared Neighborhood Hits	46
SwissProt Accessions	O60729, O43183, O60730	Gene names	CDC14B
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14B (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog B).

CC14A_MOUSE
NC score	0.198889 (rank : 47)	θ value	0.62314 (rank : 54)
Query Neighborhood Hits	164	Target Neighborhood Hits	117	Shared Neighborhood Hits	42
SwissProt Accessions	Q6GQT0, Q8BZ66	Gene names	Cdc14a
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14A (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog A).

DUS23_HUMAN
NC score	0.194649 (rank : 48)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	164	Target Neighborhood Hits	98	Shared Neighborhood Hits	35
SwissProt Accessions	Q9BVJ7, Q9NX48	Gene names	DUSP23, LDP3, VHZ
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 23 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular mass dual specificity phosphatase 3) (LDP-3) (VH1-like phosphatase Z).

CC14A_HUMAN
NC score	0.188487 (rank : 49)	θ value	1.06291 (rank : 62)
Query Neighborhood Hits	164	Target Neighborhood Hits	133	Shared Neighborhood Hits	45
SwissProt Accessions	Q9UNH5, O43171, O60727, O60728, Q8IXX0	Gene names	CDC14A
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14A (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog A).

DUS23_MOUSE
NC score	0.174217 (rank : 50)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	164	Target Neighborhood Hits	94	Shared Neighborhood Hits	33
SwissProt Accessions	Q6NT99, Q9CW48	Gene names	Dusp23, Ldp3
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 23 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular mass dual specificity phosphatase 3) (LDP-3).

CC14B_MOUSE
NC score	0.171463 (rank : 51)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	164	Target Neighborhood Hits	103	Shared Neighborhood Hits	40
SwissProt Accessions	Q6PFY9, Q80WC4, Q8BLV5	Gene names	Cdc14b
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14B (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog B).

TP4A3_HUMAN
NC score	0.062104 (rank : 52)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	164	Target Neighborhood Hits	62	Shared Neighborhood Hits	27
SwissProt Accessions	O75365, Q8IVN5, Q99849, Q9BTW5	Gene names	PTP4A3, PRL3
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a3) (Protein-tyrosine phosphatase of regenerating liver 3) (PRL-3) (PRL-R).

TP4A3_MOUSE
NC score	0.059323 (rank : 53)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	164	Target Neighborhood Hits	60	Shared Neighborhood Hits	27
SwissProt Accessions	Q9D658, O70275, Q3T9Z5, Q9CTC8	Gene names	Ptp4a3, Prl3
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a3) (Protein-tyrosine phosphatase of regenerating liver 3) (PRL-3).

ENL_HUMAN
NC score	0.051882 (rank : 54)	θ value	0.00869519 (rank : 42)
Query Neighborhood Hits	164	Target Neighborhood Hits	305	Shared Neighborhood Hits	18
SwissProt Accessions	Q03111, Q14768	Gene names	MLLT1, ENL, LTG19, YEATS1
Domain Architecture
Description	Protein ENL (YEATS domain-containing protein 1).

TP4A1_HUMAN
NC score	0.050604 (rank : 55)	θ value	6.88961 (rank : 133)
Query Neighborhood Hits	164	Target Neighborhood Hits	68	Shared Neighborhood Hits	23
SwissProt Accessions	Q93096, O00648, Q49A54	Gene names	PTP4A1, PRL1, PTPCAAX1
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a1) (Protein-tyrosine phosphatase of regenerating liver 1) (PRL-1) (PTP(CAAXI)).

TP4A1_MOUSE
NC score	0.050604 (rank : 56)	θ value	6.88961 (rank : 134)
Query Neighborhood Hits	164	Target Neighborhood Hits	68	Shared Neighborhood Hits	23
SwissProt Accessions	Q63739, O09097, O09154, Q3UFU9	Gene names	Ptp4a1, Prl1
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a1) (Protein-tyrosine phosphatase of regenerating liver 1) (PRL-1).

TMAP1_HUMAN
NC score	0.038671 (rank : 57)	θ value	1.06291 (rank : 70)
Query Neighborhood Hits	164	Target Neighborhood Hits	140	Shared Neighborhood Hits	11
SwissProt Accessions	P84157	Gene names	TMAP1
Domain Architecture	No domain graphic available
Description	Transmembrane anchor protein 1.

PELP1_MOUSE
NC score	0.035392 (rank : 58)	θ value	0.125558 (rank : 47)
Query Neighborhood Hits	164	Target Neighborhood Hits	709	Shared Neighborhood Hits	45
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

K1543_HUMAN
NC score	0.033010 (rank : 59)	θ value	5.27518 (rank : 109)
Query Neighborhood Hits	164	Target Neighborhood Hits	435	Shared Neighborhood Hits	40
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

PRRT3_HUMAN
NC score	0.031814 (rank : 60)	θ value	1.81305 (rank : 77)
Query Neighborhood Hits	164	Target Neighborhood Hits	998	Shared Neighborhood Hits	68
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

RD23B_MOUSE
NC score	0.031031 (rank : 61)	θ value	0.163984 (rank : 51)
Query Neighborhood Hits	164	Target Neighborhood Hits	189	Shared Neighborhood Hits	15
SwissProt Accessions	P54728	Gene names	Rad23b, Mhr23b
Domain Architecture
Description	UV excision repair protein RAD23 homolog B (mHR23B) (XP-C repair- complementing complex 58 kDa protein) (p58).

WBP11_HUMAN
NC score	0.030582 (rank : 62)	θ value	1.81305 (rank : 78)
Query Neighborhood Hits	164	Target Neighborhood Hits	354	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y2W2, Q96AY8	Gene names	WBP11, NPWBP, SNP70
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11) (SH3 domain-binding protein SNP70) (Npw38-binding protein) (NpwBP).

WBP11_MOUSE
NC score	0.030352 (rank : 63)	θ value	1.81305 (rank : 79)
Query Neighborhood Hits	164	Target Neighborhood Hits	362	Shared Neighborhood Hits	34
SwissProt Accessions	Q923D5, O88539, Q3UMD8, Q8VDI0	Gene names	Wbp11
Domain Architecture	No domain graphic available
Description	WW domain-binding protein 11 (WBP-11).

NACAM_MOUSE
NC score	0.029690 (rank : 64)	θ value	0.47712 (rank : 52)
Query Neighborhood Hits	164	Target Neighborhood Hits	1866	Shared Neighborhood Hits	81
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

HN1L_HUMAN
NC score	0.029492 (rank : 65)	θ value	1.06291 (rank : 65)
Query Neighborhood Hits	164	Target Neighborhood Hits	88	Shared Neighborhood Hits	16
SwissProt Accessions	Q9H910, Q6EIC7	Gene names	C16orf34, HN1L
Domain Architecture	No domain graphic available
Description	Hematological and neurological expressed 1-like protein (HN1-like protein).

BSN_MOUSE
NC score	0.029030 (rank : 66)	θ value	6.88961 (rank : 116)
Query Neighborhood Hits	164	Target Neighborhood Hits	2057	Shared Neighborhood Hits	83
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

LIPS_HUMAN
NC score	0.027976 (rank : 67)	θ value	0.813845 (rank : 60)
Query Neighborhood Hits	164	Target Neighborhood Hits	314	Shared Neighborhood Hits	28
SwissProt Accessions	Q05469, Q3LRT2, Q6NSL7	Gene names	LIPE
Domain Architecture
Description	Hormone-sensitive lipase (EC 3.1.1.79) (HSL).

YLPM1_HUMAN
NC score	0.027688 (rank : 68)	θ value	5.27518 (rank : 113)
Query Neighborhood Hits	164	Target Neighborhood Hits	670	Shared Neighborhood Hits	41
SwissProt Accessions	P49750, P49752, Q96I64, Q9P1V7	Gene names	YLPM1, C14orf170, ZAP3
Domain Architecture
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3) (ZAP113).

BAT2_HUMAN
NC score	0.027563 (rank : 69)	θ value	1.06291 (rank : 61)
Query Neighborhood Hits	164	Target Neighborhood Hits	931	Shared Neighborhood Hits	54
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

ENAH_MOUSE
NC score	0.026796 (rank : 70)	θ value	0.163984 (rank : 49)
Query Neighborhood Hits	164	Target Neighborhood Hits	919	Shared Neighborhood Hits	46
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

ODO2_MOUSE
NC score	0.025495 (rank : 71)	θ value	0.47712 (rank : 53)
Query Neighborhood Hits	164	Target Neighborhood Hits	85	Shared Neighborhood Hits	10
SwissProt Accessions	Q9D2G2	Gene names	Dlst
Domain Architecture	No domain graphic available
Description	Dihydrolipoyllysine-residue succinyltransferase component of 2- oxoglutarate dehydrogenase complex, mitochondrial precursor (EC 2.3.1.61) (Dihydrolipoamide succinyltransferase component of 2- oxoglutarate dehydrogenase complex) (E2) (E2K).

RGS3_HUMAN
NC score	0.025238 (rank : 72)	θ value	0.125558 (rank : 48)
Query Neighborhood Hits	164	Target Neighborhood Hits	1375	Shared Neighborhood Hits	69
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

K1543_MOUSE
NC score	0.024980 (rank : 73)	θ value	4.03905 (rank : 99)
Query Neighborhood Hits	164	Target Neighborhood Hits	497	Shared Neighborhood Hits	33
SwissProt Accessions	Q80VC9, Q5DTW9, Q8BUZ0	Gene names	Kiaa1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

PROM1_MOUSE
NC score	0.024752 (rank : 74)	θ value	1.81305 (rank : 76)
Query Neighborhood Hits	164	Target Neighborhood Hits	77	Shared Neighborhood Hits	5
SwissProt Accessions	O54990, O35408	Gene names	Prom1, Prom, Proml1
Domain Architecture
Description	Prominin-1 precursor (Prominin-like protein 1) (Antigen AC133 homolog).

SRRM2_MOUSE
NC score	0.024307 (rank : 75)	θ value	8.99809 (rank : 159)
Query Neighborhood Hits	164	Target Neighborhood Hits	1470	Shared Neighborhood Hits	61
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

PABP2_HUMAN
NC score	0.023739 (rank : 76)	θ value	2.36792 (rank : 82)
Query Neighborhood Hits	164	Target Neighborhood Hits	212	Shared Neighborhood Hits	6
SwissProt Accessions	Q86U42, O43484	Gene names	PABPN1, PAB2, PABP2
Domain Architecture
Description	Polyadenylate-binding protein 2 (Poly(A)-binding protein 2) (Poly(A)- binding protein II) (PABII) (Polyadenylate-binding nuclear protein 1) (Nuclear poly(A)-binding protein 1).

K1802_MOUSE
NC score	0.023642 (rank : 77)	θ value	2.36792 (rank : 81)
Query Neighborhood Hits	164	Target Neighborhood Hits	1596	Shared Neighborhood Hits	64
SwissProt Accessions	Q8K327, Q3UZ85, Q6ZPI1	Gene names	Kiaa1802, D8Ertd457e
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

PABP2_MOUSE
NC score	0.023162 (rank : 78)	θ value	2.36792 (rank : 83)
Query Neighborhood Hits	164	Target Neighborhood Hits	214	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CCS6, O35935	Gene names	Pabpn1, Pab2, Pabp2
Domain Architecture
Description	Polyadenylate-binding protein 2 (Poly(A)-binding protein 2) (Poly(A)- binding protein II) (PABII) (Polyadenylate-binding nuclear protein 1) (Nuclear poly(A)-binding protein 1).

NFH_MOUSE
NC score	0.022730 (rank : 79)	θ value	0.0252991 (rank : 43)
Query Neighborhood Hits	164	Target Neighborhood Hits	2247	Shared Neighborhood Hits	78
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

PRP1_HUMAN
NC score	0.022720 (rank : 80)	θ value	5.27518 (rank : 111)
Query Neighborhood Hits	164	Target Neighborhood Hits	385	Shared Neighborhood Hits	38
SwissProt Accessions	P04280, Q08805, Q15186, Q15187, Q15214, Q15215, Q16038	Gene names	PRB1
Domain Architecture	No domain graphic available
Description	Basic salivary proline-rich protein 1 precursor (Salivary proline-rich protein) [Contains: Basic peptide IB-6; Peptide P-H].

MINT_HUMAN
NC score	0.022583 (rank : 81)	θ value	0.62314 (rank : 55)
Query Neighborhood Hits	164	Target Neighborhood Hits	1291	Shared Neighborhood Hits	48
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

CM007_MOUSE
NC score	0.022067 (rank : 82)	θ value	1.38821 (rank : 72)
Query Neighborhood Hits	164	Target Neighborhood Hits	416	Shared Neighborhood Hits	10
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

PRR12_HUMAN
NC score	0.021795 (rank : 83)	θ value	8.99809 (rank : 158)
Query Neighborhood Hits	164	Target Neighborhood Hits	460	Shared Neighborhood Hits	41
SwissProt Accessions	Q9ULL5, Q8N4J6	Gene names	PRR12, KIAA1205
Domain Architecture	No domain graphic available
Description	Proline-rich protein 12.

TARA_HUMAN
NC score	0.021581 (rank : 84)	θ value	1.06291 (rank : 69)
Query Neighborhood Hits	164	Target Neighborhood Hits	1626	Shared Neighborhood Hits	63
SwissProt Accessions	Q9H2D6, O94797, Q2PZW8, Q2Q3Z9, Q2Q400, Q5R3M6, Q96DW1, Q9BT77, Q9BTL7, Q9BY98, Q9Y3L4	Gene names	TRIOBP, KIAA1662, TARA
Domain Architecture
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

NELFA_HUMAN
NC score	0.020994 (rank : 85)	θ value	6.88961 (rank : 126)
Query Neighborhood Hits	164	Target Neighborhood Hits	161	Shared Neighborhood Hits	24
SwissProt Accessions	Q9H3P2, O95392	Gene names	WHSC2, NELFA
Domain Architecture	No domain graphic available
Description	Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 protein).

TCOF_HUMAN
NC score	0.020865 (rank : 86)	θ value	5.27518 (rank : 112)
Query Neighborhood Hits	164	Target Neighborhood Hits	543	Shared Neighborhood Hits	25
SwissProt Accessions	Q13428, Q99408, Q99860	Gene names	TCOF1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein).

BAG3_MOUSE
NC score	0.019827 (rank : 87)	θ value	4.03905 (rank : 96)
Query Neighborhood Hits	164	Target Neighborhood Hits	513	Shared Neighborhood Hits	44
SwissProt Accessions	Q9JLV1, Q9JJC7	Gene names	Bag3, Bis
Domain Architecture
Description	BAG family molecular chaperone regulator 3 (BCL-2-binding athanogene- 3) (BAG-3) (Bcl-2-binding protein Bis).

PYGO2_HUMAN
NC score	0.019497 (rank : 88)	θ value	2.36792 (rank : 84)
Query Neighborhood Hits	164	Target Neighborhood Hits	189	Shared Neighborhood Hits	17
SwissProt Accessions	Q9BRQ0, Q8WYZ4, Q96CY2	Gene names	PYGO2
Domain Architecture
Description	Pygopus homolog 2.

PPRB_MOUSE
NC score	0.018877 (rank : 89)	θ value	4.03905 (rank : 101)
Query Neighborhood Hits	164	Target Neighborhood Hits	354	Shared Neighborhood Hits	26
SwissProt Accessions	Q925J9, O88323, Q3UHV0, Q6AXD5, Q8BW37, Q8BX19, Q8VDQ7, Q925K0	Gene names	Pparbp, Trip2
Domain Architecture	No domain graphic available
Description	Peroxisome proliferator-activated receptor-binding protein (PBP) (PPAR-binding protein) (Thyroid hormone receptor-associated protein complex 220 kDa component) (Trap220) (Thyroid receptor-interacting protein 2) (TRIP-2).

RIMB1_HUMAN
NC score	0.018777 (rank : 90)	θ value	0.0961366 (rank : 46)
Query Neighborhood Hits	164	Target Neighborhood Hits	1479	Shared Neighborhood Hits	47
SwissProt Accessions	O95153, O75111, Q8N5W3	Gene names	BZRAP1, KIAA0612, RBP1
Domain Architecture
Description	Peripheral-type benzodiazepine receptor-associated protein 1 (PRAX-1) (Peripheral benzodiazepine receptor-interacting protein) (PBR-IP) (RIM-binding protein 1) (RIM-BP1).

BSN_HUMAN
NC score	0.018313 (rank : 91)	θ value	8.99809 (rank : 139)
Query Neighborhood Hits	164	Target Neighborhood Hits	1537	Shared Neighborhood Hits	70
SwissProt Accessions	Q9UPA5, O43161, Q7LGH3	Gene names	BSN, KIAA0434, ZNF231
Domain Architecture	No domain graphic available
Description	Protein bassoon (Zinc finger protein 231).

NELFA_MOUSE
NC score	0.018124 (rank : 92)	θ value	8.99809 (rank : 153)
Query Neighborhood Hits	164	Target Neighborhood Hits	195	Shared Neighborhood Hits	20
SwissProt Accessions	Q8BG30, Q8BVE4, Q8VEI7, Q9CSJ9, Q9Z1V9	Gene names	Whsc2, Nelfa, Whsc2h
Domain Architecture	No domain graphic available
Description	Negative elongation factor A (NELF-A) (Wolf-Hirschhorn syndrome candidate 2 homolog) (mWHSC2).

PCLO_MOUSE
NC score	0.018065 (rank : 93)	θ value	3.0926 (rank : 92)
Query Neighborhood Hits	164	Target Neighborhood Hits	2275	Shared Neighborhood Hits	83
SwissProt Accessions	Q9QYX7, Q8CF91, Q8CF92, Q9QYX6, Q9QZJ0	Gene names	Pclo, Acz
Domain Architecture
Description	Protein piccolo (Aczonin) (Multidomain presynaptic cytomatrix protein) (Brain-derived HLMN protein).

NCOA6_HUMAN
NC score	0.017940 (rank : 94)	θ value	8.99809 (rank : 151)
Query Neighborhood Hits	164	Target Neighborhood Hits	1202	Shared Neighborhood Hits	63
SwissProt Accessions	Q14686, Q9NTZ9, Q9UH74, Q9UK86	Gene names	NCOA6, AIB3, KIAA0181, RAP250, TRBP
Domain Architecture	No domain graphic available
Description	Nuclear receptor coactivator 6 (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Activating signal cointegrator 2) (ASC-2) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Nuclear receptor-activating protein, 250 kDa) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Thyroid hormone receptor-binding protein).

LDB3_MOUSE
NC score	0.016876 (rank : 95)	θ value	0.163984 (rank : 50)
Query Neighborhood Hits	164	Target Neighborhood Hits	510	Shared Neighborhood Hits	31
SwissProt Accessions	Q9JKS4, Q6A038, Q811P2, Q811P3, Q811P4, Q811P5, Q9D130, Q9JKS3, Q9R0Z1, Q9WVH1, Q9WVH2	Gene names	Ldb3, Kiaa0613
Domain Architecture	No domain graphic available
Description	LIM domain-binding protein 3 (Z-band alternatively spliced PDZ-motif protein) (Protein cypher) (Protein oracle).

RIN3_HUMAN
NC score	0.016383 (rank : 96)	θ value	4.03905 (rank : 102)
Query Neighborhood Hits	164	Target Neighborhood Hits	227	Shared Neighborhood Hits	23
SwissProt Accessions	Q8TB24, Q8NF30, Q8TEE8, Q8WYP4, Q9H6A5, Q9HAG1	Gene names	RIN3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

MTSS1_HUMAN
NC score	0.016044 (rank : 97)	θ value	3.0926 (rank : 91)
Query Neighborhood Hits	164	Target Neighborhood Hits	504	Shared Neighborhood Hits	31
SwissProt Accessions	O43312, Q8TCA2, Q96RX2	Gene names	MTSS1, KIAA0429, MIM
Domain Architecture	No domain graphic available
Description	Metastasis suppressor protein 1 (Missing in metastasis protein) (Metastasis suppressor YGL-1).

K1802_HUMAN
NC score	0.015786 (rank : 98)	θ value	3.0926 (rank : 90)
Query Neighborhood Hits	164	Target Neighborhood Hits	1378	Shared Neighborhood Hits	55
SwissProt Accessions	Q96JM3, Q6P181, Q8NC88, Q9BST0	Gene names	KIAA1802, C13orf8
Domain Architecture	No domain graphic available
Description	Zinc finger protein KIAA1802.

RERE_HUMAN
NC score	0.015655 (rank : 99)	θ value	3.0926 (rank : 93)
Query Neighborhood Hits	164	Target Neighborhood Hits	779	Shared Neighborhood Hits	40
SwissProt Accessions	Q9P2R6, O43393, O75046, O75359, Q5VXL9, Q6P6B9, Q9Y2W4	Gene names	RERE, ARG, ARP, ATN1L, KIAA0458
Domain Architecture	No domain graphic available
Description	Arginine-glutamic acid dipeptide repeats protein (Atrophin-1-like protein) (Atrophin-1-related protein).

EFS_MOUSE
NC score	0.015547 (rank : 100)	θ value	6.88961 (rank : 120)
Query Neighborhood Hits	164	Target Neighborhood Hits	389	Shared Neighborhood Hits	30
SwissProt Accessions	Q64355	Gene names	Efs, Sin
Domain Architecture
Description	Embryonal Fyn-associated substrate (SRC-interacting protein) (Signal- integrating protein).

MAP1B_MOUSE
NC score	0.015378 (rank : 101)	θ value	1.06291 (rank : 66)
Query Neighborhood Hits	164	Target Neighborhood Hits	977	Shared Neighborhood Hits	28
SwissProt Accessions	P14873	Gene names	Map1b, Mtap1b, Mtap5
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) (MAP1.2) (MAP1(X)) [Contains: MAP1 light chain LC1].

MNT_HUMAN
NC score	0.015343 (rank : 102)	θ value	6.88961 (rank : 125)
Query Neighborhood Hits	164	Target Neighborhood Hits	496	Shared Neighborhood Hits	38
SwissProt Accessions	Q99583	Gene names	MNT, ROX
Domain Architecture
Description	Max-binding protein MNT (Protein ROX) (Myc antagonist MNT).

ZN409_HUMAN
NC score	0.015337 (rank : 103)	θ value	1.81305 (rank : 80)
Query Neighborhood Hits	164	Target Neighborhood Hits	842	Shared Neighborhood Hits	34
SwissProt Accessions	Q9UPU6	Gene names	ZNF409, KIAA1056
Domain Architecture	No domain graphic available
Description	Zinc finger protein 409.

SEPT9_HUMAN
NC score	0.014923 (rank : 104)	θ value	1.06291 (rank : 68)
Query Neighborhood Hits	164	Target Neighborhood Hits	706	Shared Neighborhood Hits	48
SwissProt Accessions	Q9UHD8, Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, Q9Y5W4	Gene names	SEPT9, KIAA0991, MSF
Domain Architecture	No domain graphic available
Description	Septin-9 (MLL septin-like fusion protein) (MLL septin-like fusion protein MSF-A) (Ovarian/Breast septin) (Ov/Br septin) (Septin D1).

ADDB_MOUSE
NC score	0.013724 (rank : 105)	θ value	3.0926 (rank : 85)
Query Neighborhood Hits	164	Target Neighborhood Hits	574	Shared Neighborhood Hits	27
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

EFS_HUMAN
NC score	0.013344 (rank : 106)	θ value	8.99809 (rank : 143)
Query Neighborhood Hits	164	Target Neighborhood Hits	348	Shared Neighborhood Hits	26
SwissProt Accessions	O43281, O43282	Gene names	EFS
Domain Architecture
Description	Embryonal Fyn-associated substrate (HEFS).

EPC1_MOUSE
NC score	0.013226 (rank : 107)	θ value	1.81305 (rank : 75)
Query Neighborhood Hits	164	Target Neighborhood Hits	47	Shared Neighborhood Hits	2
SwissProt Accessions	Q8C9X6, Q9Z299	Gene names	Epc1
Domain Architecture	No domain graphic available
Description	Enhancer of polycomb homolog 1.

MUCDL_HUMAN
NC score	0.012726 (rank : 108)	θ value	8.99809 (rank : 147)
Query Neighborhood Hits	164	Target Neighborhood Hits	777	Shared Neighborhood Hits	48
SwissProt Accessions	Q9HBB8, Q9H746, Q9HAU3, Q9HBB5, Q9HBB6, Q9HBB7, Q9NX86, Q9NXI9	Gene names	MUCDHL
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

AKAP2_MOUSE
NC score	0.012294 (rank : 109)	θ value	8.99809 (rank : 136)
Query Neighborhood Hits	164	Target Neighborhood Hits	385	Shared Neighborhood Hits	24
SwissProt Accessions	O54931, O54932, O54933	Gene names	Akap2
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 2 (Protein kinase A-anchoring protein 2) (PRKA2) (AKAP-2) (AKAP expressed in kidney and lung) (AKAP-KL).

NFH_HUMAN
NC score	0.012132 (rank : 110)	θ value	1.06291 (rank : 67)
Query Neighborhood Hits	164	Target Neighborhood Hits	1242	Shared Neighborhood Hits	40
SwissProt Accessions	P12036, Q9UJS7, Q9UQ14	Gene names	NEFH, KIAA0845, NFH
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

MLL2_HUMAN
NC score	0.012097 (rank : 111)	θ value	6.88961 (rank : 124)
Query Neighborhood Hits	164	Target Neighborhood Hits	1788	Shared Neighborhood Hits	63
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

SETB1_MOUSE
NC score	0.011167 (rank : 112)	θ value	6.88961 (rank : 127)
Query Neighborhood Hits	164	Target Neighborhood Hits	150	Shared Neighborhood Hits	14
SwissProt Accessions	O88974, Q922K1	Gene names	Setdb1, Eset
Domain Architecture
Description	Histone-lysine N-methyltransferase, H3 lysine-9 specific 4 (EC 2.1.1.43) (Histone H3-K9 methyltransferase 4) (H3-K9-HMTase 4) (SET domain bifurcated 1) (ERG-associated protein with SET domain) (ESET).

ABCAD_HUMAN
NC score	0.011094 (rank : 113)	θ value	1.38821 (rank : 71)
Query Neighborhood Hits	164	Target Neighborhood Hits	207	Shared Neighborhood Hits	4
SwissProt Accessions	Q86UQ4, Q6ZTT7, Q86WI2, Q8N248	Gene names	ABCA13
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 13.

STAP2_MOUSE
NC score	0.011077 (rank : 114)	θ value	8.99809 (rank : 160)
Query Neighborhood Hits	164	Target Neighborhood Hits	41	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R0L1, Q8BWS2	Gene names	Stap2
Domain Architecture	No domain graphic available
Description	Signal-transducing adaptor protein 2 (STAP-2).

FOXL1_MOUSE
NC score	0.010971 (rank : 115)	θ value	3.0926 (rank : 89)
Query Neighborhood Hits	164	Target Neighborhood Hits	152	Shared Neighborhood Hits	11
SwissProt Accessions	Q64731	Gene names	Foxl1, Fkh6, Fkhl11
Domain Architecture
Description	Forkhead box protein L1 (Forkhead-related protein FKHL11) (Transcription factor FKH-6).

RFIP3_HUMAN
NC score	0.010904 (rank : 116)	θ value	1.38821 (rank : 73)
Query Neighborhood Hits	164	Target Neighborhood Hits	1055	Shared Neighborhood Hits	30
SwissProt Accessions	O75154, Q4VXV7, Q9H155, Q9H1G0, Q9NUI0	Gene names	RAB11FIP3, KIAA0665
Domain Architecture
Description	Rab11 family-interacting protein 3 (Rab11-FIP3) (EF hands-containing Rab-interacting protein) (Eferin).

CO5A1_HUMAN
NC score	0.010708 (rank : 117)	θ value	8.99809 (rank : 140)
Query Neighborhood Hits	164	Target Neighborhood Hits	434	Shared Neighborhood Hits	27
SwissProt Accessions	P20908, Q15094, Q5SUX4	Gene names	COL5A1
Domain Architecture
Description	Collagen alpha-1(V) chain precursor.

CO5A1_MOUSE
NC score	0.010366 (rank : 118)	θ value	8.99809 (rank : 141)
Query Neighborhood Hits	164	Target Neighborhood Hits	419	Shared Neighborhood Hits	25
SwissProt Accessions	O88207	Gene names	Col5a1
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(V) chain precursor.

K1958_HUMAN
NC score	0.010211 (rank : 119)	θ value	6.88961 (rank : 122)
Query Neighborhood Hits	164	Target Neighborhood Hits	76	Shared Neighborhood Hits	8
SwissProt Accessions	Q8N8K9, Q5T252, Q8TF43, Q96N02	Gene names	KIAA1958
Domain Architecture	No domain graphic available
Description	Protein KIAA1958.

COBA2_MOUSE
NC score	0.010184 (rank : 120)	θ value	3.0926 (rank : 88)
Query Neighborhood Hits	164	Target Neighborhood Hits	501	Shared Neighborhood Hits	33
SwissProt Accessions	Q64739, Q61432, Q9Z1W0	Gene names	Col11a2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

MKL2_HUMAN
NC score	0.010041 (rank : 121)	θ value	6.88961 (rank : 123)
Query Neighborhood Hits	164	Target Neighborhood Hits	274	Shared Neighborhood Hits	19
SwissProt Accessions	Q9ULH7, Q68CT1, Q6UB16, Q86WW2, Q8N226	Gene names	MKL2, KIAA1243, MRTFB
Domain Architecture
Description	MKL/myocardin-like protein 2 (Myocardin-related transcription factor B) (MRTF-B) (Megakaryoblastic leukemia 2).

AMPH_HUMAN
NC score	0.009755 (rank : 122)	θ value	8.99809 (rank : 137)
Query Neighborhood Hits	164	Target Neighborhood Hits	455	Shared Neighborhood Hits	27
SwissProt Accessions	P49418, O43538, Q75MJ8, Q75MK5, Q75MM3, Q8N4G0	Gene names	AMPH, AMPH1
Domain Architecture
Description	Amphiphysin.

COBA2_HUMAN
NC score	0.009694 (rank : 123)	θ value	5.27518 (rank : 105)
Query Neighborhood Hits	164	Target Neighborhood Hits	408	Shared Neighborhood Hits	22
SwissProt Accessions	P13942, Q07751, Q13271, Q13272, Q13273, Q99866, Q9UIP9	Gene names	COL11A2
Domain Architecture
Description	Collagen alpha-2(XI) chain precursor.

TNR6A_HUMAN
NC score	0.009456 (rank : 124)	θ value	8.99809 (rank : 162)
Query Neighborhood Hits	164	Target Neighborhood Hits	343	Shared Neighborhood Hits	21
SwissProt Accessions	Q8NDV7, O15408, Q658L5, Q6NVB5, Q8NEZ0, Q8TBT8, Q8TCR0, Q9NV59, Q9P268	Gene names	TNRC6A, CAGH26, KIAA1460, TNRC6
Domain Architecture	No domain graphic available
Description	Trinucleotide repeat-containing gene 6A protein (CAG repeat protein 26) (Glycine-tryptophan protein of 182 kDa) (GW182 autoantigen) (Protein GW1) (EMSY interactor protein).

FOXJ2_HUMAN
NC score	0.009309 (rank : 125)	θ value	1.06291 (rank : 64)
Query Neighborhood Hits	164	Target Neighborhood Hits	239	Shared Neighborhood Hits	14
SwissProt Accessions	Q9P0K8, Q96PS9, Q9NSN5	Gene names	FOXJ2, FHX
Domain Architecture
Description	Forkhead box protein J2 (Fork head homologous X).

HHIP_MOUSE
NC score	0.009232 (rank : 126)	θ value	5.27518 (rank : 107)
Query Neighborhood Hits	164	Target Neighborhood Hits	219	Shared Neighborhood Hits	3
SwissProt Accessions	Q7TN16, Q8C0B0, Q9WU59	Gene names	Hhip, Hip
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

HHIP_HUMAN
NC score	0.008650 (rank : 127)	θ value	5.27518 (rank : 106)
Query Neighborhood Hits	164	Target Neighborhood Hits	249	Shared Neighborhood Hits	4
SwissProt Accessions	Q96QV1, Q6PK09, Q8NCI7, Q9BXK3, Q9H1J4, Q9H7E7	Gene names	HHIP, HIP
Domain Architecture	No domain graphic available
Description	Hedgehog-interacting protein precursor (HHIP) (HIP).

ATBF1_MOUSE
NC score	0.008589 (rank : 128)	θ value	6.88961 (rank : 115)
Query Neighborhood Hits	164	Target Neighborhood Hits	1841	Shared Neighborhood Hits	48
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

NCOR1_HUMAN
NC score	0.008063 (rank : 129)	θ value	8.99809 (rank : 152)
Query Neighborhood Hits	164	Target Neighborhood Hits	577	Shared Neighborhood Hits	29
SwissProt Accessions	O75376, Q9UPV5, Q9UQ18	Gene names	NCOR1, KIAA1047
Domain Architecture
Description	Nuclear receptor corepressor 1 (N-CoR1) (N-CoR).

DIAP1_HUMAN
NC score	0.007706 (rank : 130)	θ value	6.88961 (rank : 118)
Query Neighborhood Hits	164	Target Neighborhood Hits	784	Shared Neighborhood Hits	41
SwissProt Accessions	O60610, Q9UC76	Gene names	DIAPH1, DIAP1
Domain Architecture
Description	Protein diaphanous homolog 1 (Diaphanous-related formin-1) (DRF1).

ATBF1_HUMAN
NC score	0.007065 (rank : 131)	θ value	3.0926 (rank : 86)
Query Neighborhood Hits	164	Target Neighborhood Hits	1547	Shared Neighborhood Hits	36
SwissProt Accessions	Q15911, O15101, Q13719	Gene names	ATBF1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

DYNA_HUMAN
NC score	0.006989 (rank : 132)	θ value	0.813845 (rank : 57)
Query Neighborhood Hits	164	Target Neighborhood Hits	1194	Shared Neighborhood Hits	27
SwissProt Accessions	Q14203, O95296, Q9BRM9, Q9UIU1, Q9UIU2	Gene names	DCTN1
Domain Architecture
Description	Dynactin-1 (150 kDa dynein-associated polypeptide) (DP-150) (DAP-150) (p150-glued) (p135).

MCL1_MOUSE
NC score	0.006989 (rank : 133)	θ value	8.99809 (rank : 146)
Query Neighborhood Hits	164	Target Neighborhood Hits	27	Shared Neighborhood Hits	3
SwissProt Accessions	P97287, Q3TUS0, Q792P0, Q9CRI4	Gene names	Mcl1
Domain Architecture	No domain graphic available
Description	Induced myeloid leukemia cell differentiation protein Mcl-1 homolog (Bcl-2-related protein EAT/mcl1).

AP2A1_HUMAN
NC score	0.006962 (rank : 134)	θ value	8.99809 (rank : 138)
Query Neighborhood Hits	164	Target Neighborhood Hits	56	Shared Neighborhood Hits	5
SwissProt Accessions	O95782, Q96CI7, Q96PP6, Q96PP7, Q9H070	Gene names	AP2A1, ADTAA
Domain Architecture
Description	AP-2 complex subunit alpha-1 (Adapter-related protein complex 2 alpha- 1 subunit) (Alpha-adaptin A) (Adaptor protein complex AP-2 alpha-1 subunit) (Clathrin assembly protein complex 2 alpha-A large chain) (100 kDa coated vesicle protein A) (Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit).

SYNE1_HUMAN
NC score	0.006890 (rank : 135)	θ value	6.88961 (rank : 131)
Query Neighborhood Hits	164	Target Neighborhood Hits	1484	Shared Neighborhood Hits	28
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

CO4A1_MOUSE
NC score	0.006868 (rank : 136)	θ value	4.03905 (rank : 97)
Query Neighborhood Hits	164	Target Neighborhood Hits	450	Shared Neighborhood Hits	25
SwissProt Accessions	P02463	Gene names	Col4a1
Domain Architecture
Description	Collagen alpha-1(IV) chain precursor.

AP2A1_MOUSE
NC score	0.006664 (rank : 137)	θ value	6.88961 (rank : 114)
Query Neighborhood Hits	164	Target Neighborhood Hits	57	Shared Neighborhood Hits	6
SwissProt Accessions	P17426	Gene names	Ap2a1, Adtaa, Clapa1
Domain Architecture
Description	AP-2 complex subunit alpha-1 (Adapter-related protein complex 2 alpha- 1 subunit) (Alpha-adaptin A) (Adaptor protein complex AP-2 alpha-1 subunit) (Clathrin assembly protein complex 2 alpha-A large chain) (100 kDa coated vesicle protein A) (Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit).

NCOA2_MOUSE
NC score	0.006309 (rank : 138)	θ value	8.99809 (rank : 150)
Query Neighborhood Hits	164	Target Neighborhood Hits	281	Shared Neighborhood Hits	22
SwissProt Accessions	Q61026, O09001, P97759	Gene names	Ncoa2, Grip1, Tif2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2) (Glucocorticoid receptor-interacting protein 1) (GRIP-1).

TOP2A_HUMAN
NC score	0.005949 (rank : 139)	θ value	6.88961 (rank : 132)
Query Neighborhood Hits	164	Target Neighborhood Hits	135	Shared Neighborhood Hits	6
SwissProt Accessions	P11388, Q71UN1, Q9HB24, Q9HB25, Q9HB26, Q9UP44, Q9UQP9	Gene names	TOP2A, TOP2
Domain Architecture
Description	DNA topoisomerase 2-alpha (EC 5.99.1.3) (DNA topoisomerase II, alpha isozyme).

HTF4_MOUSE
NC score	0.005847 (rank : 140)	θ value	8.99809 (rank : 145)
Query Neighborhood Hits	164	Target Neighborhood Hits	153	Shared Neighborhood Hits	8
SwissProt Accessions	Q61286	Gene names	Tcf12, Alf1, Meb
Domain Architecture
Description	Transcription factor 12 (Transcription factor HTF-4) (E-box-binding protein) (DNA-binding protein HTF4) (Class A helix-loop-helix transcription factor ME1).

CSKI1_HUMAN
NC score	0.005778 (rank : 141)	θ value	8.99809 (rank : 142)
Query Neighborhood Hits	164	Target Neighborhood Hits	997	Shared Neighborhood Hits	46
SwissProt Accessions	Q8WXD9, Q9P2P0	Gene names	CASKIN1, KIAA1306
Domain Architecture	No domain graphic available
Description	Caskin-1 (CASK-interacting protein 1).

LIPB2_MOUSE
NC score	0.005493 (rank : 142)	θ value	4.03905 (rank : 100)
Query Neighborhood Hits	164	Target Neighborhood Hits	570	Shared Neighborhood Hits	15
SwissProt Accessions	O35711, Q7TMG4, Q8CBS6, Q99KX6	Gene names	Ppfibp2, Cclp1
Domain Architecture
Description	Liprin-beta-2 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2) (PTPRF-interacting protein-binding protein 2) (Coiled-coil-like protein 1).

CD248_MOUSE
NC score	0.005229 (rank : 143)	θ value	5.27518 (rank : 104)
Query Neighborhood Hits	164	Target Neighborhood Hits	578	Shared Neighborhood Hits	28
SwissProt Accessions	Q91V98, Q3UMV6, Q91ZV1	Gene names	Cd248, Tem1
Domain Architecture	No domain graphic available
Description	Endosialin precursor (Tumor endothelial marker 1) (CD248 antigen).

STAT2_MOUSE
NC score	0.005155 (rank : 144)	θ value	6.88961 (rank : 129)
Query Neighborhood Hits	164	Target Neighborhood Hits	175	Shared Neighborhood Hits	13
SwissProt Accessions	Q9WVL2, Q64188, Q64189, Q64250	Gene names	Stat2
Domain Architecture
Description	Signal transducer and activator of transcription 2.

FOXK2_HUMAN
NC score	0.004747 (rank : 145)	θ value	8.99809 (rank : 144)
Query Neighborhood Hits	164	Target Neighborhood Hits	190	Shared Neighborhood Hits	9
SwissProt Accessions	Q01167, Q13622, Q13623, Q13624	Gene names	FOXK2, ILF, ILF1
Domain Architecture
Description	Forkhead box protein K2 (Interleukin enhancer-binding factor 1) (Cellular transcription factor ILF-1).

SOX6_MOUSE
NC score	0.004680 (rank : 146)	θ value	6.88961 (rank : 128)
Query Neighborhood Hits	164	Target Neighborhood Hits	341	Shared Neighborhood Hits	17
SwissProt Accessions	P40645, Q62250, Q9QWS5	Gene names	Sox6, Sox-6
Domain Architecture
Description	Transcription factor SOX-6 (SOX-LZ).

NARGL_MOUSE
NC score	0.004671 (rank : 147)	θ value	8.99809 (rank : 149)
Query Neighborhood Hits	164	Target Neighborhood Hits	175	Shared Neighborhood Hits	4
SwissProt Accessions	Q9DBB4, Q3U7V2	Gene names	Narg1l, Nat2
Domain Architecture	No domain graphic available
Description	NMDA receptor-regulated 1-like protein (NARG1-like protein).

UBF1_HUMAN
NC score	0.004618 (rank : 148)	θ value	6.88961 (rank : 135)
Query Neighborhood Hits	164	Target Neighborhood Hits	415	Shared Neighborhood Hits	7
SwissProt Accessions	P17480	Gene names	UBTF, UBF, UBF1
Domain Architecture
Description	Nucleolar transcription factor 1 (Upstream-binding factor 1) (UBF-1) (Autoantigen NOR-90).

STX12_HUMAN
NC score	0.004512 (rank : 149)	θ value	6.88961 (rank : 130)
Query Neighborhood Hits	164	Target Neighborhood Hits	226	Shared Neighborhood Hits	4
SwissProt Accessions	Q86Y82, O95564	Gene names	STX12
Domain Architecture
Description	Syntaxin-12.

TBCD4_HUMAN
NC score	0.004264 (rank : 150)	θ value	8.99809 (rank : 161)
Query Neighborhood Hits	164	Target Neighborhood Hits	357	Shared Neighborhood Hits	8
SwissProt Accessions	O60343, Q5W0B9	Gene names	TBC1D4, KIAA0603
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 4 (Akt substrate of 160 kDa) (AS160).

ELK4_MOUSE
NC score	0.004251 (rank : 151)	θ value	6.88961 (rank : 121)
Query Neighborhood Hits	164	Target Neighborhood Hits	107	Shared Neighborhood Hits	7
SwissProt Accessions	P41158	Gene names	Elk4, Sap1
Domain Architecture
Description	ETS domain-containing protein Elk-4 (Serum response factor accessory protein 1) (SAP-1).

MYO15_HUMAN
NC score	0.004176 (rank : 152)	θ value	8.99809 (rank : 148)
Query Neighborhood Hits	164	Target Neighborhood Hits	671	Shared Neighborhood Hits	40
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

BAI1_HUMAN
NC score	0.004033 (rank : 153)	θ value	3.0926 (rank : 87)
Query Neighborhood Hits	164	Target Neighborhood Hits	375	Shared Neighborhood Hits	21
SwissProt Accessions	O14514	Gene names	BAI1
Domain Architecture
Description	Brain-specific angiogenesis inhibitor 1 precursor.

OSBL5_MOUSE
NC score	0.003989 (rank : 154)	θ value	8.99809 (rank : 156)
Query Neighborhood Hits	164	Target Neighborhood Hits	77	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ER64, Q8R510, Q99NF5	Gene names	Osbpl5, Obph1, Osbp2
Domain Architecture
Description	Oxysterol-binding protein-related protein 5 (OSBP-related protein 5) (ORP-5) (Oxysterol-binding protein homolog 1).

ISL2_HUMAN
NC score	0.002868 (rank : 155)	θ value	5.27518 (rank : 108)
Query Neighborhood Hits	164	Target Neighborhood Hits	435	Shared Neighborhood Hits	5
SwissProt Accessions	Q96A47	Gene names	ISL2
Domain Architecture
Description	Insulin gene enhancer protein ISL-2 (Islet-2).

TRIPB_HUMAN
NC score	0.002584 (rank : 156)	θ value	4.03905 (rank : 103)
Query Neighborhood Hits	164	Target Neighborhood Hits	1587	Shared Neighborhood Hits	31
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

VITRN_MOUSE
NC score	0.002511 (rank : 157)	θ value	8.99809 (rank : 163)
Query Neighborhood Hits	164	Target Neighborhood Hits	68	Shared Neighborhood Hits	2
SwissProt Accessions	Q8VHI5, Q3TZ47, Q8BQ41, Q8K047, Q9CYZ1	Gene names	Vit
Domain Architecture	No domain graphic available
Description	Vitrin precursor.

FA12_HUMAN
NC score	0.001795 (rank : 158)	θ value	0.813845 (rank : 59)
Query Neighborhood Hits	164	Target Neighborhood Hits	425	Shared Neighborhood Hits	5
SwissProt Accessions	P00748, P78339	Gene names	F12
Domain Architecture
Description	Coagulation factor XII precursor (EC 3.4.21.38) (Hageman factor) (HAF) [Contains: Coagulation factor XIIa heavy chain; Beta-factor XIIa part 1; Beta-factor XIIa part 2; Coagulation factor XIIa light chain].

NR4A2_MOUSE
NC score	0.001250 (rank : 159)	θ value	8.99809 (rank : 155)
Query Neighborhood Hits	164	Target Neighborhood Hits	121	Shared Neighborhood Hits	4
SwissProt Accessions	Q06219, O08690	Gene names	Nr4a2, Nurr1
Domain Architecture
Description	Orphan nuclear receptor NR4A2 (Orphan nuclear receptor NURR1) (NUR- related factor 1).

NR4A2_HUMAN
NC score	0.001249 (rank : 160)	θ value	8.99809 (rank : 154)
Query Neighborhood Hits	164	Target Neighborhood Hits	120	Shared Neighborhood Hits	4
SwissProt Accessions	P43354, Q16311	Gene names	NR4A2, NOT, NURR1, TINUR
Domain Architecture
Description	Orphan nuclear receptor NR4A2 (Orphan nuclear receptor NURR1) (Immediate-early response protein NOT) (Transcriptionally-inducible nuclear receptor).

PRDM2_HUMAN
NC score	0.000165 (rank : 161)	θ value	8.99809 (rank : 157)
Query Neighborhood Hits	164	Target Neighborhood Hits	1135	Shared Neighborhood Hits	32
SwissProt Accessions	Q13029, Q13149, Q14550, Q5VUL9	Gene names	PRDM2, RIZ
Domain Architecture
Description	PR domain zinc finger protein 2 (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc-finger protein) (Zinc finger protein RIZ) (MTE-binding protein) (MTB-ZF) (GATA-3-binding protein G3B).

SP7_MOUSE
NC score	-0.000487 (rank : 162)	θ value	0.62314 (rank : 56)
Query Neighborhood Hits	164	Target Neighborhood Hits	756	Shared Neighborhood Hits	12
SwissProt Accessions	Q8VI67, Q8C5R3, Q8C6A7	Gene names	Sp7, Osx
Domain Architecture	No domain graphic available
Description	Transcription factor Sp7 (Zinc finger protein osterix) (C22).

WNK1_HUMAN
NC score	-0.000991 (rank : 163)	θ value	3.0926 (rank : 95)
Query Neighborhood Hits	164	Target Neighborhood Hits	1158	Shared Neighborhood Hits	35
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

TTK_MOUSE
NC score	-0.002541 (rank : 164)	θ value	3.0926 (rank : 94)
Query Neighborhood Hits	164	Target Neighborhood Hits	803	Shared Neighborhood Hits	6
SwissProt Accessions	P35761	Gene names	Ttk, Esk
Domain Architecture
Description	Dual specificity protein kinase TTK (EC 2.7.12.1) (ESK) (PYT).

ZN358_HUMAN
NC score	-0.002602 (rank : 165)	θ value	1.38821 (rank : 74)
Query Neighborhood Hits	164	Target Neighborhood Hits	840	Shared Neighborhood Hits	24
SwissProt Accessions	Q9NW07, Q9BTM7	Gene names	ZNF358
Domain Architecture
Description	Zinc finger protein 358.

ERBB2_HUMAN
NC score	-0.002798 (rank : 166)	θ value	4.03905 (rank : 98)
Query Neighborhood Hits	164	Target Neighborhood Hits	1073	Shared Neighborhood Hits	22
SwissProt Accessions	P04626, Q14256, Q6LDV1, Q9UMK4	Gene names	ERBB2, HER2, NEU, NGL
Domain Architecture
Description	Receptor tyrosine-protein kinase erbB-2 precursor (EC 2.7.10.1) (p185erbB2) (C-erbB-2) (NEU proto-oncogene) (Tyrosine kinase-type cell surface receptor HER2) (MLN 19).

MRCKA_HUMAN
NC score	-0.003153 (rank : 167)	θ value	5.27518 (rank : 110)
Query Neighborhood Hits	164	Target Neighborhood Hits	1999	Shared Neighborhood Hits	31
SwissProt Accessions	Q5VT25, Q59GZ1, Q5H9N9, Q5T797, Q5VT26, Q5VT27, Q86XX2, Q86XX3, Q99646	Gene names	CDC42BPA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42- binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) (DMPK-like alpha).

ZXDB_HUMAN
NC score	-0.003570 (rank : 168)	θ value	8.99809 (rank : 164)
Query Neighborhood Hits	164	Target Neighborhood Hits	753	Shared Neighborhood Hits	12
SwissProt Accessions	P98169, Q9UBB3	Gene names	ZXDB
Domain Architecture	No domain graphic available
Description	Zinc finger X-linked protein ZXDB.

DUET_HUMAN
NC score	-0.004199 (rank : 169)	θ value	6.88961 (rank : 119)
Query Neighborhood Hits	164	Target Neighborhood Hits	1220	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Y2A5, Q8TBQ5, Q9NSZ4	Gene names	DUET, TRAD
Domain Architecture
Description	Serine/threonine-protein kinase Duet (EC 2.7.11.1) (Serine/threonine kinase with Dbl- and pleckstrin homology domain).