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Network neighborhood for query Sequence : SSH1_MOUSE

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SSH1_MOUSE
SwissProt Accessions	Q76I79, Q3TDG3, Q69ZM4, Q811E5	Gene names	Ssh1, Kiaa1298, Ssh1l
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 1 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-1L) (mSSH-1L).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SSH1_HUMAN
θ value	0 (rank : 1)	NC score	0.989644 (rank : 2)
Query Neighborhood Hits	107	Target Neighborhood Hits	164	Shared Neighborhood Hits	63
SwissProt Accessions	Q8WYL5, Q6P6C0, Q8N9A7, Q8WYL3, Q8WYL4, Q9P2P8	Gene names	SSH1, KIAA1298, SSH1L
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 1 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-1L) (hSSH-1L).

SSH1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	107	Target Neighborhood Hits	107	Shared Neighborhood Hits	107
SwissProt Accessions	Q76I79, Q3TDG3, Q69ZM4, Q811E5	Gene names	Ssh1, Kiaa1298, Ssh1l
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 1 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-1L) (mSSH-1L).

SSH2_HUMAN
θ value	0 (rank : 3)	NC score	0.965866 (rank : 5)
Query Neighborhood Hits	107	Target Neighborhood Hits	140	Shared Neighborhood Hits	49
SwissProt Accessions	Q76I76, Q8TDB5, Q8WYL1, Q8WYL2, Q96F40, Q96H36, Q9C0D8	Gene names	SSH2, KIAA1725, SSH2L
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 2 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-2L) (hSSH-2L).

SSH2_MOUSE
θ value	0 (rank : 4)	NC score	0.968728 (rank : 3)
Query Neighborhood Hits	107	Target Neighborhood Hits	119	Shared Neighborhood Hits	50
SwissProt Accessions	Q5SW75, Q3TDK8, Q3TYP8, Q3U2K3, Q5F268, Q5SW74, Q69ZC3, Q76I78	Gene names	Ssh2, Kiaa1725, Ssh2l
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 2 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-2L) (mSSH-2L).

SSH3_MOUSE
θ value	1.05987e-125 (rank : 5)	NC score	0.965993 (rank : 4)
Query Neighborhood Hits	107	Target Neighborhood Hits	69	Shared Neighborhood Hits	49
SwissProt Accessions	Q8K330, Q3UDX0	Gene names	Ssh3, Ssh3l
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 3 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-3L) (mSSH-3L).

SSH3_HUMAN
θ value	6.65404e-120 (rank : 6)	NC score	0.963945 (rank : 6)
Query Neighborhood Hits	107	Target Neighborhood Hits	75	Shared Neighborhood Hits	49
SwissProt Accessions	Q8TE77, Q6PK42, Q76I75, Q8N9L8, Q8WYL0, Q9NV45, Q9NWZ7	Gene names	SSH3, SSH3L
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 3 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-3L) (hSSH-3L).

DUS2_HUMAN
θ value	9.87957e-23 (rank : 7)	NC score	0.808133 (rank : 10)
Query Neighborhood Hits	107	Target Neighborhood Hits	67	Shared Neighborhood Hits	48
SwissProt Accessions	Q05923	Gene names	DUSP2, PAC1
Domain Architecture
Description	Dual specificity protein phosphatase 2 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase PAC-1).

DUS2_MOUSE
θ value	9.87957e-23 (rank : 8)	NC score	0.807946 (rank : 12)
Query Neighborhood Hits	107	Target Neighborhood Hits	86	Shared Neighborhood Hits	50
SwissProt Accessions	Q05922, Q60640	Gene names	Dusp2, Pac-1, Pac1
Domain Architecture
Description	Dual specificity protein phosphatase 2 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase PAC-1).

DUS9_HUMAN
θ value	9.87957e-23 (rank : 9)	NC score	0.815858 (rank : 9)
Query Neighborhood Hits	107	Target Neighborhood Hits	59	Shared Neighborhood Hits	48
SwissProt Accessions	Q99956	Gene names	DUSP9, MKP4
Domain Architecture
Description	Dual specificity protein phosphatase 9 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 4) (MAP kinase phosphatase 4) (MKP-4).

DUS1_HUMAN
θ value	8.36355e-22 (rank : 10)	NC score	0.789447 (rank : 22)
Query Neighborhood Hits	107	Target Neighborhood Hits	73	Shared Neighborhood Hits	50
SwissProt Accessions	P28562, Q2V508	Gene names	DUSP1, CL100, MKP1, PTPN10, VH1
Domain Architecture
Description	Dual specificity protein phosphatase 1 (EC 3.1.3.48) (EC 3.1.3.16) (MAP kinase phosphatase 1) (MKP-1) (Protein-tyrosine phosphatase CL100) (Dual specificity protein phosphatase hVH1).

DUS1_MOUSE
θ value	1.09232e-21 (rank : 11)	NC score	0.786089 (rank : 26)
Query Neighborhood Hits	107	Target Neighborhood Hits	72	Shared Neighborhood Hits	50
SwissProt Accessions	P28563	Gene names	Dusp1, 3ch134, Mkp1, Ptpn10, Ptpn16
Domain Architecture
Description	Dual specificity protein phosphatase 1 (EC 3.1.3.48) (EC 3.1.3.16) (MAP kinase phosphatase 1) (MKP-1) (Protein-tyrosine phosphatase 3CH134) (Protein-tyrosine phosphatase ERP).

DUS6_HUMAN
θ value	2.43343e-21 (rank : 12)	NC score	0.789294 (rank : 24)
Query Neighborhood Hits	107	Target Neighborhood Hits	57	Shared Neighborhood Hits	46
SwissProt Accessions	Q16828, O75109, Q53Y75, Q9BSH6	Gene names	DUSP6, MKP3, PYST1
Domain Architecture
Description	Dual specificity protein phosphatase 6 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 3) (MAP kinase phosphatase 3) (MKP-3) (Dual specificity protein phosphatase PYST1).

DUS5_HUMAN
θ value	3.17815e-21 (rank : 13)	NC score	0.804446 (rank : 16)
Query Neighborhood Hits	107	Target Neighborhood Hits	82	Shared Neighborhood Hits	51
SwissProt Accessions	Q16690, Q12997	Gene names	DUSP5, VH3
Domain Architecture
Description	Dual specificity protein phosphatase 5 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase hVH3).

DUS7_HUMAN
θ value	7.0802e-21 (rank : 14)	NC score	0.789429 (rank : 23)
Query Neighborhood Hits	107	Target Neighborhood Hits	69	Shared Neighborhood Hits	48
SwissProt Accessions	Q16829, Q8NFJ0	Gene names	DUSP7, PYST2
Domain Architecture
Description	Dual specificity protein phosphatase 7 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase PYST2).

DUS4_HUMAN
θ value	9.24701e-21 (rank : 15)	NC score	0.783336 (rank : 27)
Query Neighborhood Hits	107	Target Neighborhood Hits	77	Shared Neighborhood Hits	49
SwissProt Accessions	Q13115, Q13524	Gene names	DUSP4, MKP2, VH2
Domain Architecture
Description	Dual specificity protein phosphatase 4 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 2) (MAP kinase phosphatase 2) (MKP-2) (Dual specificity protein phosphatase hVH2).

DUS4_MOUSE
θ value	9.24701e-21 (rank : 16)	NC score	0.782574 (rank : 28)
Query Neighborhood Hits	107	Target Neighborhood Hits	75	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BFV3	Gene names	Dusp4
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 4 (EC 3.1.3.48) (EC 3.1.3.16).

DUS6_MOUSE
θ value	9.24701e-21 (rank : 17)	NC score	0.787927 (rank : 25)
Query Neighborhood Hits	107	Target Neighborhood Hits	57	Shared Neighborhood Hits	46
SwissProt Accessions	Q9DBB1, Q542I5, Q9D7L4	Gene names	Dusp6, Mkp3
Domain Architecture
Description	Dual specificity protein phosphatase 6 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 3) (MAP kinase phosphatase 3) (MKP-3).

DUS10_HUMAN
θ value	1.2077e-20 (rank : 18)	NC score	0.796037 (rank : 20)
Query Neighborhood Hits	107	Target Neighborhood Hits	64	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y6W6	Gene names	DUSP10, MKP5
Domain Architecture
Description	Dual specificity protein phosphatase 10 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 5) (MAP kinase phosphatase 5) (MKP-5).

DUS10_MOUSE
θ value	1.2077e-20 (rank : 19)	NC score	0.797054 (rank : 19)
Query Neighborhood Hits	107	Target Neighborhood Hits	62	Shared Neighborhood Hits	48
SwissProt Accessions	Q9ESS0, Q9CZY9	Gene names	Dusp10, Mkp5
Domain Architecture
Description	Dual specificity protein phosphatase 10 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 5) (MAP kinase phosphatase 5) (MKP-5).

DUS16_HUMAN
θ value	6.62687e-19 (rank : 20)	NC score	0.776353 (rank : 29)
Query Neighborhood Hits	107	Target Neighborhood Hits	112	Shared Neighborhood Hits	51
SwissProt Accessions	Q9BY84, Q9C0G3	Gene names	DUSP16, KIAA1700, MKP7
Domain Architecture
Description	Dual specificity protein phosphatase 16 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 7) (MAP kinase phosphatase 7) (MKP-7).

DUS14_HUMAN
θ value	1.13037e-18 (rank : 21)	NC score	0.798708 (rank : 18)
Query Neighborhood Hits	107	Target Neighborhood Hits	64	Shared Neighborhood Hits	47
SwissProt Accessions	O95147	Gene names	DUSP14, MKP6
Domain Architecture
Description	Dual specificity protein phosphatase 14 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 6) (MAP kinase phosphatase 6) (MKP-6) (MKP-1-like protein tyrosine phosphatase) (MKP- L).

DUS14_MOUSE
θ value	1.13037e-18 (rank : 22)	NC score	0.801634 (rank : 17)
Query Neighborhood Hits	107	Target Neighborhood Hits	67	Shared Neighborhood Hits	48
SwissProt Accessions	Q9JLY7, Q9D715	Gene names	Dusp14, Mkp6
Domain Architecture
Description	Dual specificity protein phosphatase 14 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 6) (MAP kinase phosphatase 6) (MKP-6).

DUS19_HUMAN
θ value	1.13037e-18 (rank : 23)	NC score	0.832190 (rank : 7)
Query Neighborhood Hits	107	Target Neighborhood Hits	52	Shared Neighborhood Hits	48
SwissProt Accessions	Q8WTR2, Q8WYN4	Gene names	DUSP19, DUSP17, SKRP1
Domain Architecture
Description	Dual specificity protein phosphatase 19 (EC 3.1.3.48) (EC 3.1.3.16) (Stress-activated protein kinase pathway-regulating phosphatase 1) (Protein phosphatase SKRP1).

DUS19_MOUSE
θ value	4.74913e-17 (rank : 24)	NC score	0.830481 (rank : 8)
Query Neighborhood Hits	107	Target Neighborhood Hits	58	Shared Neighborhood Hits	48
SwissProt Accessions	Q8K4T5	Gene names	Dusp19, Skrp1
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 19 (EC 3.1.3.48) (EC 3.1.3.16) (Stress-activated protein kinase pathway-regulating phosphatase 1) (Protein phosphatase SKRP1).

DUS8_HUMAN
θ value	4.74913e-17 (rank : 25)	NC score	0.760774 (rank : 34)
Query Neighborhood Hits	107	Target Neighborhood Hits	161	Shared Neighborhood Hits	54
SwissProt Accessions	Q13202	Gene names	DUSP8, VH5
Domain Architecture
Description	Dual specificity protein phosphatase 8 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase hVH-5).

DUS8_MOUSE
θ value	4.74913e-17 (rank : 26)	NC score	0.767494 (rank : 30)
Query Neighborhood Hits	107	Target Neighborhood Hits	119	Shared Neighborhood Hits	52
SwissProt Accessions	O09112	Gene names	Dusp8, Nttp1
Domain Architecture
Description	Dual specificity protein phosphatase 8 (EC 3.1.3.48) (EC 3.1.3.16) (Neuronal tyrosine threonine phosphatase 1).

DUS22_HUMAN
θ value	5.25075e-16 (rank : 27)	NC score	0.807510 (rank : 14)
Query Neighborhood Hits	107	Target Neighborhood Hits	58	Shared Neighborhood Hits	50
SwissProt Accessions	Q9NRW4, Q59GW2, Q5VWR2, Q96AR1	Gene names	DUSP22, JSP1, MKPX
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 22 (EC 3.1.3.48) (EC 3.1.3.16) (JNK-stimulatory phosphatase-1) (JSP-1) (Mitogen-activated protein kinase phosphatase x) (LMW-DSP2).

DUS22_MOUSE
θ value	6.85773e-16 (rank : 28)	NC score	0.807572 (rank : 13)
Query Neighborhood Hits	107	Target Neighborhood Hits	57	Shared Neighborhood Hits	50
SwissProt Accessions	Q99N11, Q5SQN9, Q5SQP0	Gene names	Dusp22
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 22 (EC 3.1.3.48) (EC 3.1.3.16) (LMW-DSP2).

STYX_MOUSE
θ value	8.95645e-16 (rank : 29)	NC score	0.808069 (rank : 11)
Query Neighborhood Hits	107	Target Neighborhood Hits	62	Shared Neighborhood Hits	49
SwissProt Accessions	Q60969, Q3TMA3, Q60970, Q9DCF8	Gene names	Styx
Domain Architecture
Description	Serine/threonine/tyrosine-interacting protein (Protein tyrosine phosphatase-like protein) (Phosphoserine/threonine/tyrosine interaction protein).

STYX_HUMAN
θ value	4.44505e-15 (rank : 30)	NC score	0.806808 (rank : 15)
Query Neighborhood Hits	107	Target Neighborhood Hits	60	Shared Neighborhood Hits	50
SwissProt Accessions	Q8WUJ0, Q99850	Gene names	STYX
Domain Architecture
Description	Serine/threonine/tyrosine-interacting protein (Protein tyrosine phosphatase-like protein).

DUS15_HUMAN
θ value	7.09661e-13 (rank : 31)	NC score	0.790536 (rank : 21)
Query Neighborhood Hits	107	Target Neighborhood Hits	60	Shared Neighborhood Hits	49
SwissProt Accessions	Q9H1R2, Q5QP62, Q5QP63, Q5QP65, Q6PGN7, Q8N826, Q9BX24	Gene names	DUSP15, C20orf57, VHY
Domain Architecture
Description	Dual specificity protein phosphatase 15 (EC 3.1.3.48) (EC 3.1.3.16) (Vaccinia virus VH1-related dual-specific protein phosphatase Y) (VH1- related member Y).

DUS18_HUMAN
θ value	3.52202e-12 (rank : 32)	NC score	0.763163 (rank : 33)
Query Neighborhood Hits	107	Target Neighborhood Hits	52	Shared Neighborhood Hits	47
SwissProt Accessions	Q8NEJ0	Gene names	DUSP18, LMWDSP20
Domain Architecture
Description	Dual specificity protein phosphatase 18 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular weight dual specificity phosphatase 20).

DUS18_MOUSE
θ value	4.59992e-12 (rank : 33)	NC score	0.764214 (rank : 31)
Query Neighborhood Hits	107	Target Neighborhood Hits	53	Shared Neighborhood Hits	47
SwissProt Accessions	Q8VE01	Gene names	Dusp18
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 18 (EC 3.1.3.48) (EC 3.1.3.16).

DUS12_MOUSE
θ value	1.02475e-11 (rank : 34)	NC score	0.739330 (rank : 38)
Query Neighborhood Hits	107	Target Neighborhood Hits	60	Shared Neighborhood Hits	48
SwissProt Accessions	Q9D0T2, Q9EQD3	Gene names	Dusp12
Domain Architecture
Description	Dual specificity protein phosphatase 12 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity phosphatase T-DSP4) (Dual specificity phosphatase VH1).

DUS12_HUMAN
θ value	2.28291e-11 (rank : 35)	NC score	0.733349 (rank : 40)
Query Neighborhood Hits	107	Target Neighborhood Hits	60	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UNI6	Gene names	DUSP12
Domain Architecture
Description	Dual specificity protein phosphatase 12 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity tyrosine phosphatase YVH1).

DUS21_HUMAN
θ value	2.98157e-11 (rank : 36)	NC score	0.763431 (rank : 32)
Query Neighborhood Hits	107	Target Neighborhood Hits	52	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H596, Q6IAJ6, Q6YDQ8	Gene names	DUSP21, LMWDSP21
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 21 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular weight dual specificity phosphatase 21).

DUS3_HUMAN
θ value	9.59137e-10 (rank : 37)	NC score	0.753492 (rank : 35)
Query Neighborhood Hits	107	Target Neighborhood Hits	58	Shared Neighborhood Hits	46
SwissProt Accessions	P51452	Gene names	DUSP3, VHR
Domain Architecture
Description	Dual specificity protein phosphatase 3 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase VHR).

DUS3_MOUSE
θ value	1.63604e-09 (rank : 38)	NC score	0.752869 (rank : 36)
Query Neighborhood Hits	107	Target Neighborhood Hits	54	Shared Neighborhood Hits	46
SwissProt Accessions	Q9D7X3	Gene names	Dusp3
Domain Architecture
Description	Dual specificity protein phosphatase 3 (EC 3.1.3.48) (EC 3.1.3.16) (T- DSP11).

DUS13_MOUSE
θ value	2.13673e-09 (rank : 39)	NC score	0.742517 (rank : 37)
Query Neighborhood Hits	107	Target Neighborhood Hits	56	Shared Neighborhood Hits	47
SwissProt Accessions	Q9QYJ7	Gene names	Dusp13, Tmdp
Domain Architecture
Description	Dual specificity protein phosphatase 13 (EC 3.1.3.48) (EC 3.1.3.16) (Testis- and skeletal muscle-specific DSP) (Dual specificity tyrosine phosphatase TS-DSP6).

DUS13_HUMAN
θ value	1.38499e-08 (rank : 40)	NC score	0.734895 (rank : 39)
Query Neighborhood Hits	107	Target Neighborhood Hits	59	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UII6, Q5JSC6, Q96GC2	Gene names	DUSP13, TMDP
Domain Architecture
Description	Dual specificity protein phosphatase 13 (EC 3.1.3.48) (EC 3.1.3.16) (Testis- and skeletal-muscle-specific DSP) (Dual specificity phosphatase SKRP4).

STYL1_HUMAN
θ value	1.69304e-06 (rank : 41)	NC score	0.719473 (rank : 41)
Query Neighborhood Hits	107	Target Neighborhood Hits	43	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Y6J8, Q9UBP1, Q9UK06, Q9UK07, Q9UKG2, Q9UKG3	Gene names	STYXL1, DUSP24, MKSTYX
Domain Architecture
Description	Serine/threonine/tyrosine-interacting-like protein 1 (Dual specificity protein phosphatase 24) (Map kinase phosphatase-like protein MK-STYX) (Dual specificity phosphatase inhibitor MK-STYX).

PTPM1_HUMAN
θ value	0.0431538 (rank : 42)	NC score	0.432517 (rank : 43)
Query Neighborhood Hits	107	Target Neighborhood Hits	60	Shared Neighborhood Hits	47
SwissProt Accessions	Q8WUK0, Q7Z557, Q96CR2, Q9BXV8	Gene names	PTPMT1, MOSP, PLIP
Domain Architecture	No domain graphic available
Description	Protein-tyrosine phosphatase mitochondrial 1, mitochondrial precursor (EC 3.1.3.48) (EC 3.1.3.16) (PTEN-like phosphatase) (Phosphoinositide lipid phosphatase).

KIF17_MOUSE
θ value	0.0736092 (rank : 43)	NC score	0.009883 (rank : 80)
Query Neighborhood Hits	107	Target Neighborhood Hits	452	Shared Neighborhood Hits	8
SwissProt Accessions	Q99PW8	Gene names	Kif17
Domain Architecture
Description	Kinesin-like protein KIF17 (MmKIF17).

MAST4_HUMAN
θ value	0.0736092 (rank : 44)	NC score	0.003823 (rank : 100)
Query Neighborhood Hits	107	Target Neighborhood Hits	1804	Shared Neighborhood Hits	21
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

PTPM1_MOUSE
θ value	0.0736092 (rank : 45)	NC score	0.456003 (rank : 42)
Query Neighborhood Hits	107	Target Neighborhood Hits	64	Shared Neighborhood Hits	48
SwissProt Accessions	Q66GT5, Q9CSJ8, Q9D622	Gene names	Ptpmt1, Plip
Domain Architecture	No domain graphic available
Description	Protein-tyrosine phosphatase mitochondrial 1, mitochondrial precursor (EC 3.1.3.48) (EC 3.1.3.16) (PTEN-like phosphatase) (Phosphoinositide lipid phosphatase).

ABCAD_HUMAN
θ value	0.279714 (rank : 46)	NC score	0.014470 (rank : 65)
Query Neighborhood Hits	107	Target Neighborhood Hits	207	Shared Neighborhood Hits	5
SwissProt Accessions	Q86UQ4, Q6ZTT7, Q86WI2, Q8N248	Gene names	ABCA13
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 13.

DNMT1_HUMAN
θ value	0.365318 (rank : 47)	NC score	0.023417 (rank : 62)
Query Neighborhood Hits	107	Target Neighborhood Hits	401	Shared Neighborhood Hits	11
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

SYNE1_HUMAN
θ value	0.365318 (rank : 48)	NC score	0.009840 (rank : 81)
Query Neighborhood Hits	107	Target Neighborhood Hits	1484	Shared Neighborhood Hits	19
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

ASTL_HUMAN
θ value	0.47712 (rank : 49)	NC score	0.018970 (rank : 64)
Query Neighborhood Hits	107	Target Neighborhood Hits	252	Shared Neighborhood Hits	8
SwissProt Accessions	Q6HA08	Gene names	ASTL
Domain Architecture	No domain graphic available
Description	Astacin-like metalloendopeptidase precursor (EC 3.4.-.-) (Oocyte astacin) (Ovastacin).

FOXL1_MOUSE
θ value	0.47712 (rank : 50)	NC score	0.011440 (rank : 74)
Query Neighborhood Hits	107	Target Neighborhood Hits	152	Shared Neighborhood Hits	5
SwissProt Accessions	Q64731	Gene names	Foxl1, Fkh6, Fkhl11
Domain Architecture
Description	Forkhead box protein L1 (Forkhead-related protein FKHL11) (Transcription factor FKH-6).

STAR8_HUMAN
θ value	0.47712 (rank : 51)	NC score	0.014464 (rank : 66)
Query Neighborhood Hits	107	Target Neighborhood Hits	216	Shared Neighborhood Hits	5
SwissProt Accessions	Q92502, Q5JST0	Gene names	STARD8, KIAA0189
Domain Architecture
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

AN30A_HUMAN
θ value	0.62314 (rank : 52)	NC score	0.005248 (rank : 97)
Query Neighborhood Hits	107	Target Neighborhood Hits	1119	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

CC14A_MOUSE
θ value	0.62314 (rank : 53)	NC score	0.199477 (rank : 47)
Query Neighborhood Hits	107	Target Neighborhood Hits	117	Shared Neighborhood Hits	42
SwissProt Accessions	Q6GQT0, Q8BZ66	Gene names	Cdc14a
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14A (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog A).

MPIP3_HUMAN
θ value	0.62314 (rank : 54)	NC score	0.025916 (rank : 57)
Query Neighborhood Hits	107	Target Neighborhood Hits	24	Shared Neighborhood Hits	5
SwissProt Accessions	P30307, Q96PL3, Q9H168, Q9H2E8, Q9H2E9, Q9H2F1	Gene names	CDC25C
Domain Architecture
Description	M-phase inducer phosphatase 3 (EC 3.1.3.48) (Dual specificity phosphatase Cdc25C).

RPGR1_HUMAN
θ value	0.62314 (rank : 55)	NC score	0.014255 (rank : 67)
Query Neighborhood Hits	107	Target Neighborhood Hits	578	Shared Neighborhood Hits	10
SwissProt Accessions	Q96KN7, Q7Z2W6, Q8IXV5, Q96QA8, Q9HB94, Q9HB95, Q9HBK6, Q9NR40	Gene names	RPGRIP1
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

EPM2A_MOUSE
θ value	0.813845 (rank : 56)	NC score	0.256764 (rank : 44)
Query Neighborhood Hits	107	Target Neighborhood Hits	47	Shared Neighborhood Hits	37
SwissProt Accessions	Q9WUA5, Q8BY80	Gene names	Epm2a
Domain Architecture	No domain graphic available
Description	Laforin (EC 3.1.3.48) (EC 3.1.3.16) (Lafora PTPase) (LAFPTPase).

CC14A_HUMAN
θ value	1.06291 (rank : 57)	NC score	0.188496 (rank : 49)
Query Neighborhood Hits	107	Target Neighborhood Hits	133	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UNH5, O43171, O60727, O60728, Q8IXX0	Gene names	CDC14A
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14A (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog A).

CM007_MOUSE
θ value	1.06291 (rank : 58)	NC score	0.021994 (rank : 63)
Query Neighborhood Hits	107	Target Neighborhood Hits	416	Shared Neighborhood Hits	6
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

EPM2A_HUMAN
θ value	1.06291 (rank : 59)	NC score	0.245158 (rank : 45)
Query Neighborhood Hits	107	Target Neighborhood Hits	47	Shared Neighborhood Hits	38
SwissProt Accessions	O95278, O95483, Q8IU96, Q8IX24, Q8IX25, Q9BS66, Q9UEN2	Gene names	EPM2A
Domain Architecture	No domain graphic available
Description	Laforin (EC 3.1.3.48) (EC 3.1.3.16) (Lafora PTPase) (LAFPTPase).

K1543_HUMAN
θ value	1.06291 (rank : 60)	NC score	0.023706 (rank : 59)
Query Neighborhood Hits	107	Target Neighborhood Hits	435	Shared Neighborhood Hits	10
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

TXND2_MOUSE
θ value	1.06291 (rank : 61)	NC score	0.010391 (rank : 77)
Query Neighborhood Hits	107	Target Neighborhood Hits	828	Shared Neighborhood Hits	16
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

UBP28_HUMAN
θ value	1.06291 (rank : 62)	NC score	0.012624 (rank : 71)
Query Neighborhood Hits	107	Target Neighborhood Hits	117	Shared Neighborhood Hits	3
SwissProt Accessions	Q96RU2, Q9P213	Gene names	USP28, KIAA1515
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

CE005_MOUSE
θ value	1.38821 (rank : 63)	NC score	0.011101 (rank : 75)
Query Neighborhood Hits	107	Target Neighborhood Hits	238	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K2H3	Gene names
Domain Architecture
Description	Protein C5orf5 homolog.

GATA5_HUMAN
θ value	1.38821 (rank : 64)	NC score	0.011538 (rank : 73)
Query Neighborhood Hits	107	Target Neighborhood Hits	53	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BWX5	Gene names	GATA5
Domain Architecture
Description	Transcription factor GATA-5 (GATA-binding factor 5).

IRAK3_MOUSE
θ value	1.38821 (rank : 65)	NC score	0.002315 (rank : 105)
Query Neighborhood Hits	107	Target Neighborhood Hits	628	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K4B2, Q8C7U8, Q8CE40, Q8K1S8	Gene names	Irak3
Domain Architecture	No domain graphic available
Description	Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1) (IRAK-3) (IL- 1 receptor-associated kinase M) (IRAK-M).

RGS3_MOUSE
θ value	1.38821 (rank : 66)	NC score	0.007232 (rank : 87)
Query Neighborhood Hits	107	Target Neighborhood Hits	1621	Shared Neighborhood Hits	22
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

ZCH10_MOUSE
θ value	1.38821 (rank : 67)	NC score	0.028723 (rank : 56)
Query Neighborhood Hits	107	Target Neighborhood Hits	133	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CX48	Gene names	Zcchc10
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 10.

CAC1B_MOUSE
θ value	1.81305 (rank : 68)	NC score	0.005561 (rank : 95)
Query Neighborhood Hits	107	Target Neighborhood Hits	351	Shared Neighborhood Hits	7
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

CEBPE_MOUSE
θ value	1.81305 (rank : 69)	NC score	0.013648 (rank : 68)
Query Neighborhood Hits	107	Target Neighborhood Hits	108	Shared Neighborhood Hits	2
SwissProt Accessions	Q6PZD9	Gene names	Cebpe
Domain Architecture	No domain graphic available
Description	CCAAT/enhancer-binding protein epsilon (C/EBP epsilon).

NFH_MOUSE
θ value	1.81305 (rank : 70)	NC score	0.008429 (rank : 84)
Query Neighborhood Hits	107	Target Neighborhood Hits	2247	Shared Neighborhood Hits	31
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

SI1L3_HUMAN
θ value	1.81305 (rank : 71)	NC score	0.009783 (rank : 82)
Query Neighborhood Hits	107	Target Neighborhood Hits	305	Shared Neighborhood Hits	7
SwissProt Accessions	O60292, Q2TV87	Gene names	SIPA1L3, KIAA0545, SPAL3
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 3 (SPA-1-like protein 3).

SPAG1_HUMAN
θ value	1.81305 (rank : 72)	NC score	0.009658 (rank : 83)
Query Neighborhood Hits	107	Target Neighborhood Hits	197	Shared Neighborhood Hits	3
SwissProt Accessions	Q07617, Q7Z5G1	Gene names	SPAG1
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 1 (Infertility-related sperm protein Spag-1) (HSD-3.8).

ZN623_HUMAN
θ value	1.81305 (rank : 73)	NC score	-0.003749 (rank : 111)
Query Neighborhood Hits	107	Target Neighborhood Hits	746	Shared Neighborhood Hits	4
SwissProt Accessions	O75123	Gene names	ZNF623, KIAA0628
Domain Architecture	No domain graphic available
Description	Zinc finger protein 623.

GP158_HUMAN
θ value	2.36792 (rank : 74)	NC score	0.013256 (rank : 69)
Query Neighborhood Hits	107	Target Neighborhood Hits	221	Shared Neighborhood Hits	8
SwissProt Accessions	Q5T848, Q6QR81, Q9ULT3	Gene names	GPR158, KIAA1136
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 158 precursor.

PABP2_HUMAN
θ value	2.36792 (rank : 75)	NC score	0.023657 (rank : 60)
Query Neighborhood Hits	107	Target Neighborhood Hits	212	Shared Neighborhood Hits	6
SwissProt Accessions	Q86U42, O43484	Gene names	PABPN1, PAB2, PABP2
Domain Architecture
Description	Polyadenylate-binding protein 2 (Poly(A)-binding protein 2) (Poly(A)- binding protein II) (PABII) (Polyadenylate-binding nuclear protein 1) (Nuclear poly(A)-binding protein 1).

PABP2_MOUSE
θ value	2.36792 (rank : 76)	NC score	0.023780 (rank : 58)
Query Neighborhood Hits	107	Target Neighborhood Hits	214	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CCS6, O35935	Gene names	Pabpn1, Pab2, Pabp2
Domain Architecture
Description	Polyadenylate-binding protein 2 (Poly(A)-binding protein 2) (Poly(A)- binding protein II) (PABII) (Polyadenylate-binding nuclear protein 1) (Nuclear poly(A)-binding protein 1).

PLXB1_MOUSE
θ value	2.36792 (rank : 77)	NC score	0.005945 (rank : 92)
Query Neighborhood Hits	107	Target Neighborhood Hits	259	Shared Neighborhood Hits	6
SwissProt Accessions	Q8CJH3, Q6ZQC3, Q80ZZ1	Gene names	Plxnb1, Kiaa0407
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor.

ANK2_HUMAN
θ value	3.0926 (rank : 78)	NC score	0.003315 (rank : 101)
Query Neighborhood Hits	107	Target Neighborhood Hits	1615	Shared Neighborhood Hits	24
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

PROM1_MOUSE
θ value	3.0926 (rank : 79)	NC score	0.023545 (rank : 61)
Query Neighborhood Hits	107	Target Neighborhood Hits	77	Shared Neighborhood Hits	5
SwissProt Accessions	O54990, O35408	Gene names	Prom1, Prom, Proml1
Domain Architecture
Description	Prominin-1 precursor (Prominin-like protein 1) (Antigen AC133 homolog).

SNCAP_HUMAN
θ value	3.0926 (rank : 80)	NC score	0.009972 (rank : 79)
Query Neighborhood Hits	107	Target Neighborhood Hits	313	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y6H5	Gene names	SNCAIP
Domain Architecture
Description	Synphilin-1 (Alpha-synuclein-interacting protein).

TSH1_MOUSE
θ value	3.0926 (rank : 81)	NC score	0.005676 (rank : 94)
Query Neighborhood Hits	107	Target Neighborhood Hits	675	Shared Neighborhood Hits	6
SwissProt Accessions	Q5DTH5, Q6PE60, Q8VD19, Q9JLD5	Gene names	Tshz1, Kiaa4206, Sdccag33, Tsh1
Domain Architecture	No domain graphic available
Description	Teashirt homolog 1 (Serologically defined colon cancer antigen 3 homolog).

ATX1_HUMAN
θ value	4.03905 (rank : 82)	NC score	0.012458 (rank : 72)
Query Neighborhood Hits	107	Target Neighborhood Hits	79	Shared Neighborhood Hits	4
SwissProt Accessions	P54253, Q9UJG2, Q9Y4J1	Gene names	ATXN1, ATX1, SCA1
Domain Architecture
Description	Ataxin-1 (Spinocerebellar ataxia type 1 protein).

BSN_MOUSE
θ value	4.03905 (rank : 83)	NC score	0.013151 (rank : 70)
Query Neighborhood Hits	107	Target Neighborhood Hits	2057	Shared Neighborhood Hits	31
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

FOXP4_MOUSE
θ value	4.03905 (rank : 84)	NC score	0.005683 (rank : 93)
Query Neighborhood Hits	107	Target Neighborhood Hits	211	Shared Neighborhood Hits	8
SwissProt Accessions	Q9DBY0, Q80V92, Q8CG10, Q8CIS1	Gene names	Foxp4
Domain Architecture	No domain graphic available
Description	Forkhead box protein P4 (Fork head-related protein like A) (mFKHLA).

JHD2B_HUMAN
θ value	4.03905 (rank : 85)	NC score	0.007270 (rank : 86)
Query Neighborhood Hits	107	Target Neighborhood Hits	171	Shared Neighborhood Hits	5
SwissProt Accessions	Q7LBC6, Q9BVH6, Q9BW93, Q9BZ52, Q9NYF4, Q9UPS0	Gene names	JMJD1B, C5orf7, JHDM2B, KIAA1082
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2B (EC 1.14.11.-) (Jumonji domain-containing protein 1B) (Nuclear protein 5qNCA).

MAP4_HUMAN
θ value	4.03905 (rank : 86)	NC score	0.010431 (rank : 76)
Query Neighborhood Hits	107	Target Neighborhood Hits	428	Shared Neighborhood Hits	11
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

PDZD2_HUMAN
θ value	4.03905 (rank : 87)	NC score	0.006076 (rank : 91)
Query Neighborhood Hits	107	Target Neighborhood Hits	772	Shared Neighborhood Hits	13
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

CCD21_MOUSE
θ value	5.27518 (rank : 88)	NC score	0.002481 (rank : 103)
Query Neighborhood Hits	107	Target Neighborhood Hits	1135	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BMK0, Q8BUF1, Q8K0E6	Gene names	Ccdc21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

EPC2_MOUSE
θ value	5.27518 (rank : 89)	NC score	0.008097 (rank : 85)
Query Neighborhood Hits	107	Target Neighborhood Hits	59	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C0I4, Q3URX9, Q80Y70, Q8BXC5	Gene names	Epc2
Domain Architecture	No domain graphic available
Description	Enhancer of polycomb homolog 2.

TRIPB_HUMAN
θ value	5.27518 (rank : 90)	NC score	0.002377 (rank : 104)
Query Neighborhood Hits	107	Target Neighborhood Hits	1587	Shared Neighborhood Hits	19
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

CC14B_HUMAN
θ value	6.88961 (rank : 91)	NC score	0.211221 (rank : 46)
Query Neighborhood Hits	107	Target Neighborhood Hits	114	Shared Neighborhood Hits	46
SwissProt Accessions	O60729, O43183, O60730	Gene names	CDC14B
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14B (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog B).

FMN2_MOUSE
θ value	6.88961 (rank : 92)	NC score	0.006433 (rank : 89)
Query Neighborhood Hits	107	Target Neighborhood Hits	349	Shared Neighborhood Hits	12
SwissProt Accessions	Q9JL04	Gene names	Fmn2
Domain Architecture
Description	Formin-2.

LAMC2_HUMAN
θ value	6.88961 (rank : 93)	NC score	0.000581 (rank : 108)
Query Neighborhood Hits	107	Target Neighborhood Hits	715	Shared Neighborhood Hits	7
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

MMP21_HUMAN
θ value	6.88961 (rank : 94)	NC score	0.003259 (rank : 102)
Query Neighborhood Hits	107	Target Neighborhood Hits	76	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N119, Q8NG02	Gene names	MMP21
Domain Architecture	No domain graphic available
Description	Matrix metalloproteinase-21 precursor (EC 3.4.24.-) (MMP-21).

NUMB_MOUSE
θ value	6.88961 (rank : 95)	NC score	0.006234 (rank : 90)
Query Neighborhood Hits	107	Target Neighborhood Hits	91	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QZS3, P70422, Q8CIB1, Q9DC57, Q9QZR1, Q9QZS4	Gene names	Numb
Domain Architecture
Description	Protein numb homolog (m-Numb) (m-Nb).

TP4A1_HUMAN
θ value	6.88961 (rank : 96)	NC score	0.050536 (rank : 54)
Query Neighborhood Hits	107	Target Neighborhood Hits	68	Shared Neighborhood Hits	23
SwissProt Accessions	Q93096, O00648, Q49A54	Gene names	PTP4A1, PRL1, PTPCAAX1
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a1) (Protein-tyrosine phosphatase of regenerating liver 1) (PRL-1) (PTP(CAAXI)).

TP4A1_MOUSE
θ value	6.88961 (rank : 97)	NC score	0.050536 (rank : 55)
Query Neighborhood Hits	107	Target Neighborhood Hits	68	Shared Neighborhood Hits	23
SwissProt Accessions	Q63739, O09097, O09154, Q3UFU9	Gene names	Ptp4a1, Prl1
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a1) (Protein-tyrosine phosphatase of regenerating liver 1) (PRL-1).

ZN343_HUMAN
θ value	6.88961 (rank : 98)	NC score	-0.004285 (rank : 112)
Query Neighborhood Hits	107	Target Neighborhood Hits	768	Shared Neighborhood Hits	4
SwissProt Accessions	Q6P1L6, Q5JXU8, Q5JXU9, Q8N8F2, Q96EX8, Q96NA5, Q9BQB0	Gene names	ZNF343
Domain Architecture	No domain graphic available
Description	Zinc finger protein 343.

ABCA5_HUMAN
θ value	8.99809 (rank : 99)	NC score	0.003903 (rank : 98)
Query Neighborhood Hits	107	Target Neighborhood Hits	146	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WWZ7, Q8IVJ2, Q96LJ1, Q96MS4, Q96PZ9, Q9NY14	Gene names	ABCA5, KIAA1888
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 5.

GGA1_MOUSE
θ value	8.99809 (rank : 100)	NC score	0.003892 (rank : 99)
Query Neighborhood Hits	107	Target Neighborhood Hits	128	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R0H9, Q3U2N1	Gene names	Gga1
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA1 (Golgi-localized, gamma ear-containing, ARF-binding protein 1) (Gamma-adaptin-related protein 1).

GRIN1_HUMAN
θ value	8.99809 (rank : 101)	NC score	0.005366 (rank : 96)
Query Neighborhood Hits	107	Target Neighborhood Hits	681	Shared Neighborhood Hits	13
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

MRCKA_HUMAN
θ value	8.99809 (rank : 102)	NC score	-0.003340 (rank : 110)
Query Neighborhood Hits	107	Target Neighborhood Hits	1999	Shared Neighborhood Hits	15
SwissProt Accessions	Q5VT25, Q59GZ1, Q5H9N9, Q5T797, Q5VT26, Q5VT27, Q86XX2, Q86XX3, Q99646	Gene names	CDC42BPA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42- binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) (DMPK-like alpha).

PGBM_MOUSE
θ value	8.99809 (rank : 103)	NC score	-0.002999 (rank : 109)
Query Neighborhood Hits	107	Target Neighborhood Hits	1073	Shared Neighborhood Hits	5
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

RBP2_MOUSE
θ value	8.99809 (rank : 104)	NC score	0.002103 (rank : 106)
Query Neighborhood Hits	107	Target Neighborhood Hits	232	Shared Neighborhood Hits	5
SwissProt Accessions	Q9ERU9, Q61992, Q8C9K9	Gene names	Ranbp2
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2 (RanBP2).

RGS3_HUMAN
θ value	8.99809 (rank : 105)	NC score	0.010334 (rank : 78)
Query Neighborhood Hits	107	Target Neighborhood Hits	1375	Shared Neighborhood Hits	17
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

SYNJ1_MOUSE
θ value	8.99809 (rank : 106)	NC score	0.006618 (rank : 88)
Query Neighborhood Hits	107	Target Neighborhood Hits	516	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

SYTL2_HUMAN
θ value	8.99809 (rank : 107)	NC score	0.001898 (rank : 107)
Query Neighborhood Hits	107	Target Neighborhood Hits	248	Shared Neighborhood Hits	4
SwissProt Accessions	Q9HCH5, Q2YDA7, Q8ND34, Q96BJ2, Q9H768, Q9NXM1	Gene names	SYTL2, KIAA1597, SLP2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

CC14B_MOUSE
θ value	θ > 10 (rank : 108)	NC score	0.171802 (rank : 51)
Query Neighborhood Hits	107	Target Neighborhood Hits	103	Shared Neighborhood Hits	40
SwissProt Accessions	Q6PFY9, Q80WC4, Q8BLV5	Gene names	Cdc14b
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14B (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog B).

DUS23_HUMAN
θ value	θ > 10 (rank : 109)	NC score	0.194925 (rank : 48)
Query Neighborhood Hits	107	Target Neighborhood Hits	98	Shared Neighborhood Hits	35
SwissProt Accessions	Q9BVJ7, Q9NX48	Gene names	DUSP23, LDP3, VHZ
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 23 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular mass dual specificity phosphatase 3) (LDP-3) (VH1-like phosphatase Z).

DUS23_MOUSE
θ value	θ > 10 (rank : 110)	NC score	0.174418 (rank : 50)
Query Neighborhood Hits	107	Target Neighborhood Hits	94	Shared Neighborhood Hits	33
SwissProt Accessions	Q6NT99, Q9CW48	Gene names	Dusp23, Ldp3
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 23 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular mass dual specificity phosphatase 3) (LDP-3).

TP4A3_HUMAN
θ value	θ > 10 (rank : 111)	NC score	0.062140 (rank : 52)
Query Neighborhood Hits	107	Target Neighborhood Hits	62	Shared Neighborhood Hits	27
SwissProt Accessions	O75365, Q8IVN5, Q99849, Q9BTW5	Gene names	PTP4A3, PRL3
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a3) (Protein-tyrosine phosphatase of regenerating liver 3) (PRL-3) (PRL-R).

TP4A3_MOUSE
θ value	θ > 10 (rank : 112)	NC score	0.059333 (rank : 53)
Query Neighborhood Hits	107	Target Neighborhood Hits	60	Shared Neighborhood Hits	27
SwissProt Accessions	Q9D658, O70275, Q3T9Z5, Q9CTC8	Gene names	Ptp4a3, Prl3
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a3) (Protein-tyrosine phosphatase of regenerating liver 3) (PRL-3).

Hits sorted by NC score

SSH1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	107	Target Neighborhood Hits	107	Shared Neighborhood Hits	107
SwissProt Accessions	Q76I79, Q3TDG3, Q69ZM4, Q811E5	Gene names	Ssh1, Kiaa1298, Ssh1l
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 1 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-1L) (mSSH-1L).

SSH1_HUMAN
NC score	0.989644 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	107	Target Neighborhood Hits	164	Shared Neighborhood Hits	63
SwissProt Accessions	Q8WYL5, Q6P6C0, Q8N9A7, Q8WYL3, Q8WYL4, Q9P2P8	Gene names	SSH1, KIAA1298, SSH1L
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 1 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-1L) (hSSH-1L).

SSH2_MOUSE
NC score	0.968728 (rank : 3)	θ value	0 (rank : 4)
Query Neighborhood Hits	107	Target Neighborhood Hits	119	Shared Neighborhood Hits	50
SwissProt Accessions	Q5SW75, Q3TDK8, Q3TYP8, Q3U2K3, Q5F268, Q5SW74, Q69ZC3, Q76I78	Gene names	Ssh2, Kiaa1725, Ssh2l
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 2 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-2L) (mSSH-2L).

SSH3_MOUSE
NC score	0.965993 (rank : 4)	θ value	1.05987e-125 (rank : 5)
Query Neighborhood Hits	107	Target Neighborhood Hits	69	Shared Neighborhood Hits	49
SwissProt Accessions	Q8K330, Q3UDX0	Gene names	Ssh3, Ssh3l
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 3 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-3L) (mSSH-3L).

SSH2_HUMAN
NC score	0.965866 (rank : 5)	θ value	0 (rank : 3)
Query Neighborhood Hits	107	Target Neighborhood Hits	140	Shared Neighborhood Hits	49
SwissProt Accessions	Q76I76, Q8TDB5, Q8WYL1, Q8WYL2, Q96F40, Q96H36, Q9C0D8	Gene names	SSH2, KIAA1725, SSH2L
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 2 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-2L) (hSSH-2L).

SSH3_HUMAN
NC score	0.963945 (rank : 6)	θ value	6.65404e-120 (rank : 6)
Query Neighborhood Hits	107	Target Neighborhood Hits	75	Shared Neighborhood Hits	49
SwissProt Accessions	Q8TE77, Q6PK42, Q76I75, Q8N9L8, Q8WYL0, Q9NV45, Q9NWZ7	Gene names	SSH3, SSH3L
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 3 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-3L) (hSSH-3L).

DUS19_HUMAN
NC score	0.832190 (rank : 7)	θ value	1.13037e-18 (rank : 23)
Query Neighborhood Hits	107	Target Neighborhood Hits	52	Shared Neighborhood Hits	48
SwissProt Accessions	Q8WTR2, Q8WYN4	Gene names	DUSP19, DUSP17, SKRP1
Domain Architecture
Description	Dual specificity protein phosphatase 19 (EC 3.1.3.48) (EC 3.1.3.16) (Stress-activated protein kinase pathway-regulating phosphatase 1) (Protein phosphatase SKRP1).

DUS19_MOUSE
NC score	0.830481 (rank : 8)	θ value	4.74913e-17 (rank : 24)
Query Neighborhood Hits	107	Target Neighborhood Hits	58	Shared Neighborhood Hits	48
SwissProt Accessions	Q8K4T5	Gene names	Dusp19, Skrp1
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 19 (EC 3.1.3.48) (EC 3.1.3.16) (Stress-activated protein kinase pathway-regulating phosphatase 1) (Protein phosphatase SKRP1).

DUS9_HUMAN
NC score	0.815858 (rank : 9)	θ value	9.87957e-23 (rank : 9)
Query Neighborhood Hits	107	Target Neighborhood Hits	59	Shared Neighborhood Hits	48
SwissProt Accessions	Q99956	Gene names	DUSP9, MKP4
Domain Architecture
Description	Dual specificity protein phosphatase 9 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 4) (MAP kinase phosphatase 4) (MKP-4).

DUS2_HUMAN
NC score	0.808133 (rank : 10)	θ value	9.87957e-23 (rank : 7)
Query Neighborhood Hits	107	Target Neighborhood Hits	67	Shared Neighborhood Hits	48
SwissProt Accessions	Q05923	Gene names	DUSP2, PAC1
Domain Architecture
Description	Dual specificity protein phosphatase 2 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase PAC-1).

STYX_MOUSE
NC score	0.808069 (rank : 11)	θ value	8.95645e-16 (rank : 29)
Query Neighborhood Hits	107	Target Neighborhood Hits	62	Shared Neighborhood Hits	49
SwissProt Accessions	Q60969, Q3TMA3, Q60970, Q9DCF8	Gene names	Styx
Domain Architecture
Description	Serine/threonine/tyrosine-interacting protein (Protein tyrosine phosphatase-like protein) (Phosphoserine/threonine/tyrosine interaction protein).

DUS2_MOUSE
NC score	0.807946 (rank : 12)	θ value	9.87957e-23 (rank : 8)
Query Neighborhood Hits	107	Target Neighborhood Hits	86	Shared Neighborhood Hits	50
SwissProt Accessions	Q05922, Q60640	Gene names	Dusp2, Pac-1, Pac1
Domain Architecture
Description	Dual specificity protein phosphatase 2 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase PAC-1).

DUS22_MOUSE
NC score	0.807572 (rank : 13)	θ value	6.85773e-16 (rank : 28)
Query Neighborhood Hits	107	Target Neighborhood Hits	57	Shared Neighborhood Hits	50
SwissProt Accessions	Q99N11, Q5SQN9, Q5SQP0	Gene names	Dusp22
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 22 (EC 3.1.3.48) (EC 3.1.3.16) (LMW-DSP2).

DUS22_HUMAN
NC score	0.807510 (rank : 14)	θ value	5.25075e-16 (rank : 27)
Query Neighborhood Hits	107	Target Neighborhood Hits	58	Shared Neighborhood Hits	50
SwissProt Accessions	Q9NRW4, Q59GW2, Q5VWR2, Q96AR1	Gene names	DUSP22, JSP1, MKPX
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 22 (EC 3.1.3.48) (EC 3.1.3.16) (JNK-stimulatory phosphatase-1) (JSP-1) (Mitogen-activated protein kinase phosphatase x) (LMW-DSP2).

STYX_HUMAN
NC score	0.806808 (rank : 15)	θ value	4.44505e-15 (rank : 30)
Query Neighborhood Hits	107	Target Neighborhood Hits	60	Shared Neighborhood Hits	50
SwissProt Accessions	Q8WUJ0, Q99850	Gene names	STYX
Domain Architecture
Description	Serine/threonine/tyrosine-interacting protein (Protein tyrosine phosphatase-like protein).

DUS5_HUMAN
NC score	0.804446 (rank : 16)	θ value	3.17815e-21 (rank : 13)
Query Neighborhood Hits	107	Target Neighborhood Hits	82	Shared Neighborhood Hits	51
SwissProt Accessions	Q16690, Q12997	Gene names	DUSP5, VH3
Domain Architecture
Description	Dual specificity protein phosphatase 5 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase hVH3).

DUS14_MOUSE
NC score	0.801634 (rank : 17)	θ value	1.13037e-18 (rank : 22)
Query Neighborhood Hits	107	Target Neighborhood Hits	67	Shared Neighborhood Hits	48
SwissProt Accessions	Q9JLY7, Q9D715	Gene names	Dusp14, Mkp6
Domain Architecture
Description	Dual specificity protein phosphatase 14 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 6) (MAP kinase phosphatase 6) (MKP-6).

DUS14_HUMAN
NC score	0.798708 (rank : 18)	θ value	1.13037e-18 (rank : 21)
Query Neighborhood Hits	107	Target Neighborhood Hits	64	Shared Neighborhood Hits	47
SwissProt Accessions	O95147	Gene names	DUSP14, MKP6
Domain Architecture
Description	Dual specificity protein phosphatase 14 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 6) (MAP kinase phosphatase 6) (MKP-6) (MKP-1-like protein tyrosine phosphatase) (MKP- L).

DUS10_MOUSE
NC score	0.797054 (rank : 19)	θ value	1.2077e-20 (rank : 19)
Query Neighborhood Hits	107	Target Neighborhood Hits	62	Shared Neighborhood Hits	48
SwissProt Accessions	Q9ESS0, Q9CZY9	Gene names	Dusp10, Mkp5
Domain Architecture
Description	Dual specificity protein phosphatase 10 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 5) (MAP kinase phosphatase 5) (MKP-5).

DUS10_HUMAN
NC score	0.796037 (rank : 20)	θ value	1.2077e-20 (rank : 18)
Query Neighborhood Hits	107	Target Neighborhood Hits	64	Shared Neighborhood Hits	48
SwissProt Accessions	Q9Y6W6	Gene names	DUSP10, MKP5
Domain Architecture
Description	Dual specificity protein phosphatase 10 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 5) (MAP kinase phosphatase 5) (MKP-5).

DUS15_HUMAN
NC score	0.790536 (rank : 21)	θ value	7.09661e-13 (rank : 31)
Query Neighborhood Hits	107	Target Neighborhood Hits	60	Shared Neighborhood Hits	49
SwissProt Accessions	Q9H1R2, Q5QP62, Q5QP63, Q5QP65, Q6PGN7, Q8N826, Q9BX24	Gene names	DUSP15, C20orf57, VHY
Domain Architecture
Description	Dual specificity protein phosphatase 15 (EC 3.1.3.48) (EC 3.1.3.16) (Vaccinia virus VH1-related dual-specific protein phosphatase Y) (VH1- related member Y).

DUS1_HUMAN
NC score	0.789447 (rank : 22)	θ value	8.36355e-22 (rank : 10)
Query Neighborhood Hits	107	Target Neighborhood Hits	73	Shared Neighborhood Hits	50
SwissProt Accessions	P28562, Q2V508	Gene names	DUSP1, CL100, MKP1, PTPN10, VH1
Domain Architecture
Description	Dual specificity protein phosphatase 1 (EC 3.1.3.48) (EC 3.1.3.16) (MAP kinase phosphatase 1) (MKP-1) (Protein-tyrosine phosphatase CL100) (Dual specificity protein phosphatase hVH1).

DUS7_HUMAN
NC score	0.789429 (rank : 23)	θ value	7.0802e-21 (rank : 14)
Query Neighborhood Hits	107	Target Neighborhood Hits	69	Shared Neighborhood Hits	48
SwissProt Accessions	Q16829, Q8NFJ0	Gene names	DUSP7, PYST2
Domain Architecture
Description	Dual specificity protein phosphatase 7 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase PYST2).

DUS6_HUMAN
NC score	0.789294 (rank : 24)	θ value	2.43343e-21 (rank : 12)
Query Neighborhood Hits	107	Target Neighborhood Hits	57	Shared Neighborhood Hits	46
SwissProt Accessions	Q16828, O75109, Q53Y75, Q9BSH6	Gene names	DUSP6, MKP3, PYST1
Domain Architecture
Description	Dual specificity protein phosphatase 6 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 3) (MAP kinase phosphatase 3) (MKP-3) (Dual specificity protein phosphatase PYST1).

DUS6_MOUSE
NC score	0.787927 (rank : 25)	θ value	9.24701e-21 (rank : 17)
Query Neighborhood Hits	107	Target Neighborhood Hits	57	Shared Neighborhood Hits	46
SwissProt Accessions	Q9DBB1, Q542I5, Q9D7L4	Gene names	Dusp6, Mkp3
Domain Architecture
Description	Dual specificity protein phosphatase 6 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 3) (MAP kinase phosphatase 3) (MKP-3).

DUS1_MOUSE
NC score	0.786089 (rank : 26)	θ value	1.09232e-21 (rank : 11)
Query Neighborhood Hits	107	Target Neighborhood Hits	72	Shared Neighborhood Hits	50
SwissProt Accessions	P28563	Gene names	Dusp1, 3ch134, Mkp1, Ptpn10, Ptpn16
Domain Architecture
Description	Dual specificity protein phosphatase 1 (EC 3.1.3.48) (EC 3.1.3.16) (MAP kinase phosphatase 1) (MKP-1) (Protein-tyrosine phosphatase 3CH134) (Protein-tyrosine phosphatase ERP).

DUS4_HUMAN
NC score	0.783336 (rank : 27)	θ value	9.24701e-21 (rank : 15)
Query Neighborhood Hits	107	Target Neighborhood Hits	77	Shared Neighborhood Hits	49
SwissProt Accessions	Q13115, Q13524	Gene names	DUSP4, MKP2, VH2
Domain Architecture
Description	Dual specificity protein phosphatase 4 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 2) (MAP kinase phosphatase 2) (MKP-2) (Dual specificity protein phosphatase hVH2).

DUS4_MOUSE
NC score	0.782574 (rank : 28)	θ value	9.24701e-21 (rank : 16)
Query Neighborhood Hits	107	Target Neighborhood Hits	75	Shared Neighborhood Hits	49
SwissProt Accessions	Q8BFV3	Gene names	Dusp4
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 4 (EC 3.1.3.48) (EC 3.1.3.16).

DUS16_HUMAN
NC score	0.776353 (rank : 29)	θ value	6.62687e-19 (rank : 20)
Query Neighborhood Hits	107	Target Neighborhood Hits	112	Shared Neighborhood Hits	51
SwissProt Accessions	Q9BY84, Q9C0G3	Gene names	DUSP16, KIAA1700, MKP7
Domain Architecture
Description	Dual specificity protein phosphatase 16 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 7) (MAP kinase phosphatase 7) (MKP-7).

DUS8_MOUSE
NC score	0.767494 (rank : 30)	θ value	4.74913e-17 (rank : 26)
Query Neighborhood Hits	107	Target Neighborhood Hits	119	Shared Neighborhood Hits	52
SwissProt Accessions	O09112	Gene names	Dusp8, Nttp1
Domain Architecture
Description	Dual specificity protein phosphatase 8 (EC 3.1.3.48) (EC 3.1.3.16) (Neuronal tyrosine threonine phosphatase 1).

DUS18_MOUSE
NC score	0.764214 (rank : 31)	θ value	4.59992e-12 (rank : 33)
Query Neighborhood Hits	107	Target Neighborhood Hits	53	Shared Neighborhood Hits	47
SwissProt Accessions	Q8VE01	Gene names	Dusp18
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 18 (EC 3.1.3.48) (EC 3.1.3.16).

DUS21_HUMAN
NC score	0.763431 (rank : 32)	θ value	2.98157e-11 (rank : 36)
Query Neighborhood Hits	107	Target Neighborhood Hits	52	Shared Neighborhood Hits	48
SwissProt Accessions	Q9H596, Q6IAJ6, Q6YDQ8	Gene names	DUSP21, LMWDSP21
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 21 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular weight dual specificity phosphatase 21).

DUS18_HUMAN
NC score	0.763163 (rank : 33)	θ value	3.52202e-12 (rank : 32)
Query Neighborhood Hits	107	Target Neighborhood Hits	52	Shared Neighborhood Hits	47
SwissProt Accessions	Q8NEJ0	Gene names	DUSP18, LMWDSP20
Domain Architecture
Description	Dual specificity protein phosphatase 18 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular weight dual specificity phosphatase 20).

DUS8_HUMAN
NC score	0.760774 (rank : 34)	θ value	4.74913e-17 (rank : 25)
Query Neighborhood Hits	107	Target Neighborhood Hits	161	Shared Neighborhood Hits	54
SwissProt Accessions	Q13202	Gene names	DUSP8, VH5
Domain Architecture
Description	Dual specificity protein phosphatase 8 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase hVH-5).

DUS3_HUMAN
NC score	0.753492 (rank : 35)	θ value	9.59137e-10 (rank : 37)
Query Neighborhood Hits	107	Target Neighborhood Hits	58	Shared Neighborhood Hits	46
SwissProt Accessions	P51452	Gene names	DUSP3, VHR
Domain Architecture
Description	Dual specificity protein phosphatase 3 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase VHR).

DUS3_MOUSE
NC score	0.752869 (rank : 36)	θ value	1.63604e-09 (rank : 38)
Query Neighborhood Hits	107	Target Neighborhood Hits	54	Shared Neighborhood Hits	46
SwissProt Accessions	Q9D7X3	Gene names	Dusp3
Domain Architecture
Description	Dual specificity protein phosphatase 3 (EC 3.1.3.48) (EC 3.1.3.16) (T- DSP11).

DUS13_MOUSE
NC score	0.742517 (rank : 37)	θ value	2.13673e-09 (rank : 39)
Query Neighborhood Hits	107	Target Neighborhood Hits	56	Shared Neighborhood Hits	47
SwissProt Accessions	Q9QYJ7	Gene names	Dusp13, Tmdp
Domain Architecture
Description	Dual specificity protein phosphatase 13 (EC 3.1.3.48) (EC 3.1.3.16) (Testis- and skeletal muscle-specific DSP) (Dual specificity tyrosine phosphatase TS-DSP6).

DUS12_MOUSE
NC score	0.739330 (rank : 38)	θ value	1.02475e-11 (rank : 34)
Query Neighborhood Hits	107	Target Neighborhood Hits	60	Shared Neighborhood Hits	48
SwissProt Accessions	Q9D0T2, Q9EQD3	Gene names	Dusp12
Domain Architecture
Description	Dual specificity protein phosphatase 12 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity phosphatase T-DSP4) (Dual specificity phosphatase VH1).

DUS13_HUMAN
NC score	0.734895 (rank : 39)	θ value	1.38499e-08 (rank : 40)
Query Neighborhood Hits	107	Target Neighborhood Hits	59	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UII6, Q5JSC6, Q96GC2	Gene names	DUSP13, TMDP
Domain Architecture
Description	Dual specificity protein phosphatase 13 (EC 3.1.3.48) (EC 3.1.3.16) (Testis- and skeletal-muscle-specific DSP) (Dual specificity phosphatase SKRP4).

DUS12_HUMAN
NC score	0.733349 (rank : 40)	θ value	2.28291e-11 (rank : 35)
Query Neighborhood Hits	107	Target Neighborhood Hits	60	Shared Neighborhood Hits	46
SwissProt Accessions	Q9UNI6	Gene names	DUSP12
Domain Architecture
Description	Dual specificity protein phosphatase 12 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity tyrosine phosphatase YVH1).

STYL1_HUMAN
NC score	0.719473 (rank : 41)	θ value	1.69304e-06 (rank : 41)
Query Neighborhood Hits	107	Target Neighborhood Hits	43	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Y6J8, Q9UBP1, Q9UK06, Q9UK07, Q9UKG2, Q9UKG3	Gene names	STYXL1, DUSP24, MKSTYX
Domain Architecture
Description	Serine/threonine/tyrosine-interacting-like protein 1 (Dual specificity protein phosphatase 24) (Map kinase phosphatase-like protein MK-STYX) (Dual specificity phosphatase inhibitor MK-STYX).

PTPM1_MOUSE
NC score	0.456003 (rank : 42)	θ value	0.0736092 (rank : 45)
Query Neighborhood Hits	107	Target Neighborhood Hits	64	Shared Neighborhood Hits	48
SwissProt Accessions	Q66GT5, Q9CSJ8, Q9D622	Gene names	Ptpmt1, Plip
Domain Architecture	No domain graphic available
Description	Protein-tyrosine phosphatase mitochondrial 1, mitochondrial precursor (EC 3.1.3.48) (EC 3.1.3.16) (PTEN-like phosphatase) (Phosphoinositide lipid phosphatase).

PTPM1_HUMAN
NC score	0.432517 (rank : 43)	θ value	0.0431538 (rank : 42)
Query Neighborhood Hits	107	Target Neighborhood Hits	60	Shared Neighborhood Hits	47
SwissProt Accessions	Q8WUK0, Q7Z557, Q96CR2, Q9BXV8	Gene names	PTPMT1, MOSP, PLIP
Domain Architecture	No domain graphic available
Description	Protein-tyrosine phosphatase mitochondrial 1, mitochondrial precursor (EC 3.1.3.48) (EC 3.1.3.16) (PTEN-like phosphatase) (Phosphoinositide lipid phosphatase).

EPM2A_MOUSE
NC score	0.256764 (rank : 44)	θ value	0.813845 (rank : 56)
Query Neighborhood Hits	107	Target Neighborhood Hits	47	Shared Neighborhood Hits	37
SwissProt Accessions	Q9WUA5, Q8BY80	Gene names	Epm2a
Domain Architecture	No domain graphic available
Description	Laforin (EC 3.1.3.48) (EC 3.1.3.16) (Lafora PTPase) (LAFPTPase).

EPM2A_HUMAN
NC score	0.245158 (rank : 45)	θ value	1.06291 (rank : 59)
Query Neighborhood Hits	107	Target Neighborhood Hits	47	Shared Neighborhood Hits	38
SwissProt Accessions	O95278, O95483, Q8IU96, Q8IX24, Q8IX25, Q9BS66, Q9UEN2	Gene names	EPM2A
Domain Architecture	No domain graphic available
Description	Laforin (EC 3.1.3.48) (EC 3.1.3.16) (Lafora PTPase) (LAFPTPase).

CC14B_HUMAN
NC score	0.211221 (rank : 46)	θ value	6.88961 (rank : 91)
Query Neighborhood Hits	107	Target Neighborhood Hits	114	Shared Neighborhood Hits	46
SwissProt Accessions	O60729, O43183, O60730	Gene names	CDC14B
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14B (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog B).

CC14A_MOUSE
NC score	0.199477 (rank : 47)	θ value	0.62314 (rank : 53)
Query Neighborhood Hits	107	Target Neighborhood Hits	117	Shared Neighborhood Hits	42
SwissProt Accessions	Q6GQT0, Q8BZ66	Gene names	Cdc14a
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14A (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog A).

DUS23_HUMAN
NC score	0.194925 (rank : 48)	θ value	θ > 10 (rank : 109)
Query Neighborhood Hits	107	Target Neighborhood Hits	98	Shared Neighborhood Hits	35
SwissProt Accessions	Q9BVJ7, Q9NX48	Gene names	DUSP23, LDP3, VHZ
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 23 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular mass dual specificity phosphatase 3) (LDP-3) (VH1-like phosphatase Z).

CC14A_HUMAN
NC score	0.188496 (rank : 49)	θ value	1.06291 (rank : 57)
Query Neighborhood Hits	107	Target Neighborhood Hits	133	Shared Neighborhood Hits	42
SwissProt Accessions	Q9UNH5, O43171, O60727, O60728, Q8IXX0	Gene names	CDC14A
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14A (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog A).

DUS23_MOUSE
NC score	0.174418 (rank : 50)	θ value	θ > 10 (rank : 110)
Query Neighborhood Hits	107	Target Neighborhood Hits	94	Shared Neighborhood Hits	33
SwissProt Accessions	Q6NT99, Q9CW48	Gene names	Dusp23, Ldp3
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 23 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular mass dual specificity phosphatase 3) (LDP-3).

CC14B_MOUSE
NC score	0.171802 (rank : 51)	θ value	θ > 10 (rank : 108)
Query Neighborhood Hits	107	Target Neighborhood Hits	103	Shared Neighborhood Hits	40
SwissProt Accessions	Q6PFY9, Q80WC4, Q8BLV5	Gene names	Cdc14b
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14B (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog B).

TP4A3_HUMAN
NC score	0.062140 (rank : 52)	θ value	θ > 10 (rank : 111)
Query Neighborhood Hits	107	Target Neighborhood Hits	62	Shared Neighborhood Hits	27
SwissProt Accessions	O75365, Q8IVN5, Q99849, Q9BTW5	Gene names	PTP4A3, PRL3
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a3) (Protein-tyrosine phosphatase of regenerating liver 3) (PRL-3) (PRL-R).

TP4A3_MOUSE
NC score	0.059333 (rank : 53)	θ value	θ > 10 (rank : 112)
Query Neighborhood Hits	107	Target Neighborhood Hits	60	Shared Neighborhood Hits	27
SwissProt Accessions	Q9D658, O70275, Q3T9Z5, Q9CTC8	Gene names	Ptp4a3, Prl3
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a3) (Protein-tyrosine phosphatase of regenerating liver 3) (PRL-3).

TP4A1_HUMAN
NC score	0.050536 (rank : 54)	θ value	6.88961 (rank : 96)
Query Neighborhood Hits	107	Target Neighborhood Hits	68	Shared Neighborhood Hits	23
SwissProt Accessions	Q93096, O00648, Q49A54	Gene names	PTP4A1, PRL1, PTPCAAX1
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a1) (Protein-tyrosine phosphatase of regenerating liver 1) (PRL-1) (PTP(CAAXI)).

TP4A1_MOUSE
NC score	0.050536 (rank : 55)	θ value	6.88961 (rank : 97)
Query Neighborhood Hits	107	Target Neighborhood Hits	68	Shared Neighborhood Hits	23
SwissProt Accessions	Q63739, O09097, O09154, Q3UFU9	Gene names	Ptp4a1, Prl1
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a1) (Protein-tyrosine phosphatase of regenerating liver 1) (PRL-1).

ZCH10_MOUSE
NC score	0.028723 (rank : 56)	θ value	1.38821 (rank : 67)
Query Neighborhood Hits	107	Target Neighborhood Hits	133	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CX48	Gene names	Zcchc10
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 10.

MPIP3_HUMAN
NC score	0.025916 (rank : 57)	θ value	0.62314 (rank : 54)
Query Neighborhood Hits	107	Target Neighborhood Hits	24	Shared Neighborhood Hits	5
SwissProt Accessions	P30307, Q96PL3, Q9H168, Q9H2E8, Q9H2E9, Q9H2F1	Gene names	CDC25C
Domain Architecture
Description	M-phase inducer phosphatase 3 (EC 3.1.3.48) (Dual specificity phosphatase Cdc25C).

PABP2_MOUSE
NC score	0.023780 (rank : 58)	θ value	2.36792 (rank : 76)
Query Neighborhood Hits	107	Target Neighborhood Hits	214	Shared Neighborhood Hits	7
SwissProt Accessions	Q8CCS6, O35935	Gene names	Pabpn1, Pab2, Pabp2
Domain Architecture
Description	Polyadenylate-binding protein 2 (Poly(A)-binding protein 2) (Poly(A)- binding protein II) (PABII) (Polyadenylate-binding nuclear protein 1) (Nuclear poly(A)-binding protein 1).

K1543_HUMAN
NC score	0.023706 (rank : 59)	θ value	1.06291 (rank : 60)
Query Neighborhood Hits	107	Target Neighborhood Hits	435	Shared Neighborhood Hits	10
SwissProt Accessions	Q9P1Y5, Q8NDF1	Gene names	KIAA1543
Domain Architecture	No domain graphic available
Description	Protein KIAA1543.

PABP2_HUMAN
NC score	0.023657 (rank : 60)	θ value	2.36792 (rank : 75)
Query Neighborhood Hits	107	Target Neighborhood Hits	212	Shared Neighborhood Hits	6
SwissProt Accessions	Q86U42, O43484	Gene names	PABPN1, PAB2, PABP2
Domain Architecture
Description	Polyadenylate-binding protein 2 (Poly(A)-binding protein 2) (Poly(A)- binding protein II) (PABII) (Polyadenylate-binding nuclear protein 1) (Nuclear poly(A)-binding protein 1).

PROM1_MOUSE
NC score	0.023545 (rank : 61)	θ value	3.0926 (rank : 79)
Query Neighborhood Hits	107	Target Neighborhood Hits	77	Shared Neighborhood Hits	5
SwissProt Accessions	O54990, O35408	Gene names	Prom1, Prom, Proml1
Domain Architecture
Description	Prominin-1 precursor (Prominin-like protein 1) (Antigen AC133 homolog).

DNMT1_HUMAN
NC score	0.023417 (rank : 62)	θ value	0.365318 (rank : 47)
Query Neighborhood Hits	107	Target Neighborhood Hits	401	Shared Neighborhood Hits	11
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

CM007_MOUSE
NC score	0.021994 (rank : 63)	θ value	1.06291 (rank : 58)
Query Neighborhood Hits	107	Target Neighborhood Hits	416	Shared Neighborhood Hits	6
SwissProt Accessions	Q8K2Y0, Q9CYU1, Q9D1Y0	Gene names
Domain Architecture	No domain graphic available
Description	Protein C13orf7 homolog.

ASTL_HUMAN
NC score	0.018970 (rank : 64)	θ value	0.47712 (rank : 49)
Query Neighborhood Hits	107	Target Neighborhood Hits	252	Shared Neighborhood Hits	8
SwissProt Accessions	Q6HA08	Gene names	ASTL
Domain Architecture	No domain graphic available
Description	Astacin-like metalloendopeptidase precursor (EC 3.4.-.-) (Oocyte astacin) (Ovastacin).

ABCAD_HUMAN
NC score	0.014470 (rank : 65)	θ value	0.279714 (rank : 46)
Query Neighborhood Hits	107	Target Neighborhood Hits	207	Shared Neighborhood Hits	5
SwissProt Accessions	Q86UQ4, Q6ZTT7, Q86WI2, Q8N248	Gene names	ABCA13
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 13.

STAR8_HUMAN
NC score	0.014464 (rank : 66)	θ value	0.47712 (rank : 51)
Query Neighborhood Hits	107	Target Neighborhood Hits	216	Shared Neighborhood Hits	5
SwissProt Accessions	Q92502, Q5JST0	Gene names	STARD8, KIAA0189
Domain Architecture
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

RPGR1_HUMAN
NC score	0.014255 (rank : 67)	θ value	0.62314 (rank : 55)
Query Neighborhood Hits	107	Target Neighborhood Hits	578	Shared Neighborhood Hits	10
SwissProt Accessions	Q96KN7, Q7Z2W6, Q8IXV5, Q96QA8, Q9HB94, Q9HB95, Q9HBK6, Q9NR40	Gene names	RPGRIP1
Domain Architecture
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

CEBPE_MOUSE
NC score	0.013648 (rank : 68)	θ value	1.81305 (rank : 69)
Query Neighborhood Hits	107	Target Neighborhood Hits	108	Shared Neighborhood Hits	2
SwissProt Accessions	Q6PZD9	Gene names	Cebpe
Domain Architecture	No domain graphic available
Description	CCAAT/enhancer-binding protein epsilon (C/EBP epsilon).

GP158_HUMAN
NC score	0.013256 (rank : 69)	θ value	2.36792 (rank : 74)
Query Neighborhood Hits	107	Target Neighborhood Hits	221	Shared Neighborhood Hits	8
SwissProt Accessions	Q5T848, Q6QR81, Q9ULT3	Gene names	GPR158, KIAA1136
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 158 precursor.

BSN_MOUSE
NC score	0.013151 (rank : 70)	θ value	4.03905 (rank : 83)
Query Neighborhood Hits	107	Target Neighborhood Hits	2057	Shared Neighborhood Hits	31
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

UBP28_HUMAN
NC score	0.012624 (rank : 71)	θ value	1.06291 (rank : 62)
Query Neighborhood Hits	107	Target Neighborhood Hits	117	Shared Neighborhood Hits	3
SwissProt Accessions	Q96RU2, Q9P213	Gene names	USP28, KIAA1515
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.1.2.15) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28) (Deubiquitinating enzyme 28).

ATX1_HUMAN
NC score	0.012458 (rank : 72)	θ value	4.03905 (rank : 82)
Query Neighborhood Hits	107	Target Neighborhood Hits	79	Shared Neighborhood Hits	4
SwissProt Accessions	P54253, Q9UJG2, Q9Y4J1	Gene names	ATXN1, ATX1, SCA1
Domain Architecture
Description	Ataxin-1 (Spinocerebellar ataxia type 1 protein).

GATA5_HUMAN
NC score	0.011538 (rank : 73)	θ value	1.38821 (rank : 64)
Query Neighborhood Hits	107	Target Neighborhood Hits	53	Shared Neighborhood Hits	2
SwissProt Accessions	Q9BWX5	Gene names	GATA5
Domain Architecture
Description	Transcription factor GATA-5 (GATA-binding factor 5).

FOXL1_MOUSE
NC score	0.011440 (rank : 74)	θ value	0.47712 (rank : 50)
Query Neighborhood Hits	107	Target Neighborhood Hits	152	Shared Neighborhood Hits	5
SwissProt Accessions	Q64731	Gene names	Foxl1, Fkh6, Fkhl11
Domain Architecture
Description	Forkhead box protein L1 (Forkhead-related protein FKHL11) (Transcription factor FKH-6).

CE005_MOUSE
NC score	0.011101 (rank : 75)	θ value	1.38821 (rank : 63)
Query Neighborhood Hits	107	Target Neighborhood Hits	238	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K2H3	Gene names
Domain Architecture
Description	Protein C5orf5 homolog.

MAP4_HUMAN
NC score	0.010431 (rank : 76)	θ value	4.03905 (rank : 86)
Query Neighborhood Hits	107	Target Neighborhood Hits	428	Shared Neighborhood Hits	11
SwissProt Accessions	P27816, Q13082, Q96A76	Gene names	MAP4
Domain Architecture
Description	Microtubule-associated protein 4 (MAP 4).

TXND2_MOUSE
NC score	0.010391 (rank : 77)	θ value	1.06291 (rank : 61)
Query Neighborhood Hits	107	Target Neighborhood Hits	828	Shared Neighborhood Hits	16
SwissProt Accessions	Q6P902, Q8CJD1	Gene names	Txndc2, Sptrx, Sptrx1, Trx4
Domain Architecture	No domain graphic available
Description	Thioredoxin domain-containing protein 2 (Spermatid-specific thioredoxin-1) (Sptrx-1) (Thioredoxin-4).

RGS3_HUMAN
NC score	0.010334 (rank : 78)	θ value	8.99809 (rank : 105)
Query Neighborhood Hits	107	Target Neighborhood Hits	1375	Shared Neighborhood Hits	17
SwissProt Accessions	P49796, Q5VXC1, Q5VZ05, Q6ZRM5, Q8IUQ1, Q8NC47, Q8NFN4, Q8NFN5, Q8TD59, Q8TD68, Q8WXA0	Gene names	RGS3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (RGP3).

SNCAP_HUMAN
NC score	0.009972 (rank : 79)	θ value	3.0926 (rank : 80)
Query Neighborhood Hits	107	Target Neighborhood Hits	313	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Y6H5	Gene names	SNCAIP
Domain Architecture
Description	Synphilin-1 (Alpha-synuclein-interacting protein).

KIF17_MOUSE
NC score	0.009883 (rank : 80)	θ value	0.0736092 (rank : 43)
Query Neighborhood Hits	107	Target Neighborhood Hits	452	Shared Neighborhood Hits	8
SwissProt Accessions	Q99PW8	Gene names	Kif17
Domain Architecture
Description	Kinesin-like protein KIF17 (MmKIF17).

SYNE1_HUMAN
NC score	0.009840 (rank : 81)	θ value	0.365318 (rank : 48)
Query Neighborhood Hits	107	Target Neighborhood Hits	1484	Shared Neighborhood Hits	19
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

SI1L3_HUMAN
NC score	0.009783 (rank : 82)	θ value	1.81305 (rank : 71)
Query Neighborhood Hits	107	Target Neighborhood Hits	305	Shared Neighborhood Hits	7
SwissProt Accessions	O60292, Q2TV87	Gene names	SIPA1L3, KIAA0545, SPAL3
Domain Architecture	No domain graphic available
Description	Signal-induced proliferation-associated 1-like protein 3 (SPA-1-like protein 3).

SPAG1_HUMAN
NC score	0.009658 (rank : 83)	θ value	1.81305 (rank : 72)
Query Neighborhood Hits	107	Target Neighborhood Hits	197	Shared Neighborhood Hits	3
SwissProt Accessions	Q07617, Q7Z5G1	Gene names	SPAG1
Domain Architecture	No domain graphic available
Description	Sperm-associated antigen 1 (Infertility-related sperm protein Spag-1) (HSD-3.8).

NFH_MOUSE
NC score	0.008429 (rank : 84)	θ value	1.81305 (rank : 70)
Query Neighborhood Hits	107	Target Neighborhood Hits	2247	Shared Neighborhood Hits	31
SwissProt Accessions	P19246, Q5SVF6, Q61959	Gene names	Nefh, Nfh
Domain Architecture
Description	Neurofilament triplet H protein (200 kDa neurofilament protein) (Neurofilament heavy polypeptide) (NF-H).

EPC2_MOUSE
NC score	0.008097 (rank : 85)	θ value	5.27518 (rank : 89)
Query Neighborhood Hits	107	Target Neighborhood Hits	59	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C0I4, Q3URX9, Q80Y70, Q8BXC5	Gene names	Epc2
Domain Architecture	No domain graphic available
Description	Enhancer of polycomb homolog 2.

JHD2B_HUMAN
NC score	0.007270 (rank : 86)	θ value	4.03905 (rank : 85)
Query Neighborhood Hits	107	Target Neighborhood Hits	171	Shared Neighborhood Hits	5
SwissProt Accessions	Q7LBC6, Q9BVH6, Q9BW93, Q9BZ52, Q9NYF4, Q9UPS0	Gene names	JMJD1B, C5orf7, JHDM2B, KIAA1082
Domain Architecture	No domain graphic available
Description	JmjC domain-containing histone demethylation protein 2B (EC 1.14.11.-) (Jumonji domain-containing protein 1B) (Nuclear protein 5qNCA).

RGS3_MOUSE
NC score	0.007232 (rank : 87)	θ value	1.38821 (rank : 66)
Query Neighborhood Hits	107	Target Neighborhood Hits	1621	Shared Neighborhood Hits	22
SwissProt Accessions	Q9DC04, Q5SRB1, Q5SRB4, Q5SRB8, Q8CEE3, Q8VI25, Q925G9, Q9JL22, Q9JL23, Q9QXA2	Gene names	Rgs3
Domain Architecture
Description	Regulator of G-protein signaling 3 (RGS3) (C2PA).

SYNJ1_MOUSE
NC score	0.006618 (rank : 88)	θ value	8.99809 (rank : 106)
Query Neighborhood Hits	107	Target Neighborhood Hits	516	Shared Neighborhood Hits	15
SwissProt Accessions	Q8CHC4	Gene names	Synj1, Kiaa0910
Domain Architecture
Description	Synaptojanin-1 (EC 3.1.3.36) (Synaptic inositol-1,4,5-trisphosphate 5- phosphatase 1).

FMN2_MOUSE
NC score	0.006433 (rank : 89)	θ value	6.88961 (rank : 92)
Query Neighborhood Hits	107	Target Neighborhood Hits	349	Shared Neighborhood Hits	12
SwissProt Accessions	Q9JL04	Gene names	Fmn2
Domain Architecture
Description	Formin-2.

NUMB_MOUSE
NC score	0.006234 (rank : 90)	θ value	6.88961 (rank : 95)
Query Neighborhood Hits	107	Target Neighborhood Hits	91	Shared Neighborhood Hits	3
SwissProt Accessions	Q9QZS3, P70422, Q8CIB1, Q9DC57, Q9QZR1, Q9QZS4	Gene names	Numb
Domain Architecture
Description	Protein numb homolog (m-Numb) (m-Nb).

PDZD2_HUMAN
NC score	0.006076 (rank : 91)	θ value	4.03905 (rank : 87)
Query Neighborhood Hits	107	Target Neighborhood Hits	772	Shared Neighborhood Hits	13
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

PLXB1_MOUSE
NC score	0.005945 (rank : 92)	θ value	2.36792 (rank : 77)
Query Neighborhood Hits	107	Target Neighborhood Hits	259	Shared Neighborhood Hits	6
SwissProt Accessions	Q8CJH3, Q6ZQC3, Q80ZZ1	Gene names	Plxnb1, Kiaa0407
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor.

FOXP4_MOUSE
NC score	0.005683 (rank : 93)	θ value	4.03905 (rank : 84)
Query Neighborhood Hits	107	Target Neighborhood Hits	211	Shared Neighborhood Hits	8
SwissProt Accessions	Q9DBY0, Q80V92, Q8CG10, Q8CIS1	Gene names	Foxp4
Domain Architecture	No domain graphic available
Description	Forkhead box protein P4 (Fork head-related protein like A) (mFKHLA).

TSH1_MOUSE
NC score	0.005676 (rank : 94)	θ value	3.0926 (rank : 81)
Query Neighborhood Hits	107	Target Neighborhood Hits	675	Shared Neighborhood Hits	6
SwissProt Accessions	Q5DTH5, Q6PE60, Q8VD19, Q9JLD5	Gene names	Tshz1, Kiaa4206, Sdccag33, Tsh1
Domain Architecture	No domain graphic available
Description	Teashirt homolog 1 (Serologically defined colon cancer antigen 3 homolog).

CAC1B_MOUSE
NC score	0.005561 (rank : 95)	θ value	1.81305 (rank : 68)
Query Neighborhood Hits	107	Target Neighborhood Hits	351	Shared Neighborhood Hits	7
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

GRIN1_HUMAN
NC score	0.005366 (rank : 96)	θ value	8.99809 (rank : 101)
Query Neighborhood Hits	107	Target Neighborhood Hits	681	Shared Neighborhood Hits	13
SwissProt Accessions	Q7Z2K8, Q8ND74, Q96PZ4	Gene names	GPRIN1, KIAA1893
Domain Architecture	No domain graphic available
Description	G protein-regulated inducer of neurite outgrowth 1 (GRIN1).

AN30A_HUMAN
NC score	0.005248 (rank : 97)	θ value	0.62314 (rank : 52)
Query Neighborhood Hits	107	Target Neighborhood Hits	1119	Shared Neighborhood Hits	13
SwissProt Accessions	Q9BXX3, Q5W025	Gene names	ANKRD30A
Domain Architecture	No domain graphic available
Description	Ankyrin repeat domain-containing protein 30A (NY-BR-1 antigen).

ABCA5_HUMAN
NC score	0.003903 (rank : 98)	θ value	8.99809 (rank : 99)
Query Neighborhood Hits	107	Target Neighborhood Hits	146	Shared Neighborhood Hits	4
SwissProt Accessions	Q8WWZ7, Q8IVJ2, Q96LJ1, Q96MS4, Q96PZ9, Q9NY14	Gene names	ABCA5, KIAA1888
Domain Architecture	No domain graphic available
Description	ATP-binding cassette sub-family A member 5.

GGA1_MOUSE
NC score	0.003892 (rank : 99)	θ value	8.99809 (rank : 100)
Query Neighborhood Hits	107	Target Neighborhood Hits	128	Shared Neighborhood Hits	6
SwissProt Accessions	Q8R0H9, Q3U2N1	Gene names	Gga1
Domain Architecture	No domain graphic available
Description	ADP-ribosylation factor-binding protein GGA1 (Golgi-localized, gamma ear-containing, ARF-binding protein 1) (Gamma-adaptin-related protein 1).

MAST4_HUMAN
NC score	0.003823 (rank : 100)	θ value	0.0736092 (rank : 44)
Query Neighborhood Hits	107	Target Neighborhood Hits	1804	Shared Neighborhood Hits	21
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

ANK2_HUMAN
NC score	0.003315 (rank : 101)	θ value	3.0926 (rank : 78)
Query Neighborhood Hits	107	Target Neighborhood Hits	1615	Shared Neighborhood Hits	24
SwissProt Accessions	Q01484, Q01485	Gene names	ANK2
Domain Architecture
Description	Ankyrin-2 (Brain ankyrin) (Ankyrin-B) (Ankyrin, nonerythroid).

MMP21_HUMAN
NC score	0.003259 (rank : 102)	θ value	6.88961 (rank : 94)
Query Neighborhood Hits	107	Target Neighborhood Hits	76	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N119, Q8NG02	Gene names	MMP21
Domain Architecture	No domain graphic available
Description	Matrix metalloproteinase-21 precursor (EC 3.4.24.-) (MMP-21).

CCD21_MOUSE
NC score	0.002481 (rank : 103)	θ value	5.27518 (rank : 88)
Query Neighborhood Hits	107	Target Neighborhood Hits	1135	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BMK0, Q8BUF1, Q8K0E6	Gene names	Ccdc21
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 21.

TRIPB_HUMAN
NC score	0.002377 (rank : 104)	θ value	5.27518 (rank : 90)
Query Neighborhood Hits	107	Target Neighborhood Hits	1587	Shared Neighborhood Hits	19
SwissProt Accessions	Q15643, O14689, O15154, O95949	Gene names	TRIP11, CEV14
Domain Architecture	No domain graphic available
Description	Thyroid receptor-interacting protein 11 (TRIP-11) (Golgi-associated microtubule-binding protein 210) (GMAP-210) (Trip230) (Clonal evolution-related gene on chromosome 14).

IRAK3_MOUSE
NC score	0.002315 (rank : 105)	θ value	1.38821 (rank : 65)
Query Neighborhood Hits	107	Target Neighborhood Hits	628	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K4B2, Q8C7U8, Q8CE40, Q8K1S8	Gene names	Irak3
Domain Architecture	No domain graphic available
Description	Interleukin-1 receptor-associated kinase 3 (EC 2.7.11.1) (IRAK-3) (IL- 1 receptor-associated kinase M) (IRAK-M).

RBP2_MOUSE
NC score	0.002103 (rank : 106)	θ value	8.99809 (rank : 104)
Query Neighborhood Hits	107	Target Neighborhood Hits	232	Shared Neighborhood Hits	5
SwissProt Accessions	Q9ERU9, Q61992, Q8C9K9	Gene names	Ranbp2
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2 (RanBP2).

SYTL2_HUMAN
NC score	0.001898 (rank : 107)	θ value	8.99809 (rank : 107)
Query Neighborhood Hits	107	Target Neighborhood Hits	248	Shared Neighborhood Hits	4
SwissProt Accessions	Q9HCH5, Q2YDA7, Q8ND34, Q96BJ2, Q9H768, Q9NXM1	Gene names	SYTL2, KIAA1597, SLP2
Domain Architecture
Description	Synaptotagmin-like protein 2 (Exophilin-4).

LAMC2_HUMAN
NC score	0.000581 (rank : 108)	θ value	6.88961 (rank : 93)
Query Neighborhood Hits	107	Target Neighborhood Hits	715	Shared Neighborhood Hits	7
SwissProt Accessions	Q13753, Q02536, Q02537, Q13752, Q14941, Q5VYE8	Gene names	LAMC2
Domain Architecture
Description	Laminin gamma-2 chain precursor (Laminin 5 gamma 2 subunit) (Kalinin/nicein/epiligrin 100 kDa subunit) (Laminin B2t chain) (Cell- scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Large adhesive scatter factor 140 kDa subunit) (Ladsin 140 kDa subunit).

PGBM_MOUSE
NC score	-0.002999 (rank : 109)	θ value	8.99809 (rank : 103)
Query Neighborhood Hits	107	Target Neighborhood Hits	1073	Shared Neighborhood Hits	5
SwissProt Accessions	Q05793	Gene names	Hspg2
Domain Architecture
Description	Basement membrane-specific heparan sulfate proteoglycan core protein precursor (HSPG) (Perlecan) (PLC).

MRCKA_HUMAN
NC score	-0.003340 (rank : 110)	θ value	8.99809 (rank : 102)
Query Neighborhood Hits	107	Target Neighborhood Hits	1999	Shared Neighborhood Hits	15
SwissProt Accessions	Q5VT25, Q59GZ1, Q5H9N9, Q5T797, Q5VT26, Q5VT27, Q86XX2, Q86XX3, Q99646	Gene names	CDC42BPA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42- binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) (DMPK-like alpha).

ZN623_HUMAN
NC score	-0.003749 (rank : 111)	θ value	1.81305 (rank : 73)
Query Neighborhood Hits	107	Target Neighborhood Hits	746	Shared Neighborhood Hits	4
SwissProt Accessions	O75123	Gene names	ZNF623, KIAA0628
Domain Architecture	No domain graphic available
Description	Zinc finger protein 623.

ZN343_HUMAN
NC score	-0.004285 (rank : 112)	θ value	6.88961 (rank : 98)
Query Neighborhood Hits	107	Target Neighborhood Hits	768	Shared Neighborhood Hits	4
SwissProt Accessions	Q6P1L6, Q5JXU8, Q5JXU9, Q8N8F2, Q96EX8, Q96NA5, Q9BQB0	Gene names	ZNF343
Domain Architecture	No domain graphic available
Description	Zinc finger protein 343.