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Network neighborhood for query Sequence : DUS16_HUMAN

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DUS16_HUMAN
SwissProt Accessions	Q9BY84, Q9C0G3	Gene names	DUSP16, KIAA1700, MKP7
Domain Architecture
Description	Dual specificity protein phosphatase 16 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 7) (MAP kinase phosphatase 7) (MKP-7).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

DUS16_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	112	Target Neighborhood Hits	112	Shared Neighborhood Hits	112
SwissProt Accessions	Q9BY84, Q9C0G3	Gene names	DUSP16, KIAA1700, MKP7
Domain Architecture
Description	Dual specificity protein phosphatase 16 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 7) (MAP kinase phosphatase 7) (MKP-7).

DUS8_HUMAN
θ value	1.4755e-135 (rank : 2)	NC score	0.970683 (rank : 3)
Query Neighborhood Hits	112	Target Neighborhood Hits	161	Shared Neighborhood Hits	62
SwissProt Accessions	Q13202	Gene names	DUSP8, VH5
Domain Architecture
Description	Dual specificity protein phosphatase 8 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase hVH-5).

DUS8_MOUSE
θ value	5.80223e-132 (rank : 3)	NC score	0.975594 (rank : 2)
Query Neighborhood Hits	112	Target Neighborhood Hits	119	Shared Neighborhood Hits	61
SwissProt Accessions	O09112	Gene names	Dusp8, Nttp1
Domain Architecture
Description	Dual specificity protein phosphatase 8 (EC 3.1.3.48) (EC 3.1.3.16) (Neuronal tyrosine threonine phosphatase 1).

DUS10_HUMAN
θ value	4.122e-45 (rank : 4)	NC score	0.940214 (rank : 5)
Query Neighborhood Hits	112	Target Neighborhood Hits	64	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Y6W6	Gene names	DUSP10, MKP5
Domain Architecture
Description	Dual specificity protein phosphatase 10 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 5) (MAP kinase phosphatase 5) (MKP-5).

DUS10_MOUSE
θ value	5.38352e-45 (rank : 5)	NC score	0.940942 (rank : 4)
Query Neighborhood Hits	112	Target Neighborhood Hits	62	Shared Neighborhood Hits	55
SwissProt Accessions	Q9ESS0, Q9CZY9	Gene names	Dusp10, Mkp5
Domain Architecture
Description	Dual specificity protein phosphatase 10 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 5) (MAP kinase phosphatase 5) (MKP-5).

DUS6_HUMAN
θ value	3.85808e-43 (rank : 6)	NC score	0.930512 (rank : 10)
Query Neighborhood Hits	112	Target Neighborhood Hits	57	Shared Neighborhood Hits	52
SwissProt Accessions	Q16828, O75109, Q53Y75, Q9BSH6	Gene names	DUSP6, MKP3, PYST1
Domain Architecture
Description	Dual specificity protein phosphatase 6 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 3) (MAP kinase phosphatase 3) (MKP-3) (Dual specificity protein phosphatase PYST1).

DUS6_MOUSE
θ value	1.12253e-42 (rank : 7)	NC score	0.930104 (rank : 11)
Query Neighborhood Hits	112	Target Neighborhood Hits	57	Shared Neighborhood Hits	52
SwissProt Accessions	Q9DBB1, Q542I5, Q9D7L4	Gene names	Dusp6, Mkp3
Domain Architecture
Description	Dual specificity protein phosphatase 6 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 3) (MAP kinase phosphatase 3) (MKP-3).

DUS4_HUMAN
θ value	3.99248e-40 (rank : 8)	NC score	0.925747 (rank : 14)
Query Neighborhood Hits	112	Target Neighborhood Hits	77	Shared Neighborhood Hits	62
SwissProt Accessions	Q13115, Q13524	Gene names	DUSP4, MKP2, VH2
Domain Architecture
Description	Dual specificity protein phosphatase 4 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 2) (MAP kinase phosphatase 2) (MKP-2) (Dual specificity protein phosphatase hVH2).

DUS1_MOUSE
θ value	1.16164e-39 (rank : 9)	NC score	0.925962 (rank : 13)
Query Neighborhood Hits	112	Target Neighborhood Hits	72	Shared Neighborhood Hits	62
SwissProt Accessions	P28563	Gene names	Dusp1, 3ch134, Mkp1, Ptpn10, Ptpn16
Domain Architecture
Description	Dual specificity protein phosphatase 1 (EC 3.1.3.48) (EC 3.1.3.16) (MAP kinase phosphatase 1) (MKP-1) (Protein-tyrosine phosphatase 3CH134) (Protein-tyrosine phosphatase ERP).

DUS4_MOUSE
θ value	1.16164e-39 (rank : 10)	NC score	0.925137 (rank : 15)
Query Neighborhood Hits	112	Target Neighborhood Hits	75	Shared Neighborhood Hits	62
SwissProt Accessions	Q8BFV3	Gene names	Dusp4
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 4 (EC 3.1.3.48) (EC 3.1.3.16).

DUS7_HUMAN
θ value	1.51715e-39 (rank : 11)	NC score	0.932721 (rank : 9)
Query Neighborhood Hits	112	Target Neighborhood Hits	69	Shared Neighborhood Hits	57
SwissProt Accessions	Q16829, Q8NFJ0	Gene names	DUSP7, PYST2
Domain Architecture
Description	Dual specificity protein phosphatase 7 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase PYST2).

DUS1_HUMAN
θ value	7.52953e-39 (rank : 12)	NC score	0.926228 (rank : 12)
Query Neighborhood Hits	112	Target Neighborhood Hits	73	Shared Neighborhood Hits	61
SwissProt Accessions	P28562, Q2V508	Gene names	DUSP1, CL100, MKP1, PTPN10, VH1
Domain Architecture
Description	Dual specificity protein phosphatase 1 (EC 3.1.3.48) (EC 3.1.3.16) (MAP kinase phosphatase 1) (MKP-1) (Protein-tyrosine phosphatase CL100) (Dual specificity protein phosphatase hVH1).

DUS2_HUMAN
θ value	6.37413e-38 (rank : 13)	NC score	0.933794 (rank : 8)
Query Neighborhood Hits	112	Target Neighborhood Hits	67	Shared Neighborhood Hits	61
SwissProt Accessions	Q05923	Gene names	DUSP2, PAC1
Domain Architecture
Description	Dual specificity protein phosphatase 2 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase PAC-1).

DUS2_MOUSE
θ value	8.32485e-38 (rank : 14)	NC score	0.934961 (rank : 7)
Query Neighborhood Hits	112	Target Neighborhood Hits	86	Shared Neighborhood Hits	70
SwissProt Accessions	Q05922, Q60640	Gene names	Dusp2, Pac-1, Pac1
Domain Architecture
Description	Dual specificity protein phosphatase 2 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase PAC-1).

DUS9_HUMAN
θ value	3.86705e-35 (rank : 15)	NC score	0.939078 (rank : 6)
Query Neighborhood Hits	112	Target Neighborhood Hits	59	Shared Neighborhood Hits	55
SwissProt Accessions	Q99956	Gene names	DUSP9, MKP4
Domain Architecture
Description	Dual specificity protein phosphatase 9 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 4) (MAP kinase phosphatase 4) (MKP-4).

DUS5_HUMAN
θ value	9.8567e-31 (rank : 16)	NC score	0.924205 (rank : 16)
Query Neighborhood Hits	112	Target Neighborhood Hits	82	Shared Neighborhood Hits	61
SwissProt Accessions	Q16690, Q12997	Gene names	DUSP5, VH3
Domain Architecture
Description	Dual specificity protein phosphatase 5 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase hVH3).

DUS14_HUMAN
θ value	4.9032e-22 (rank : 17)	NC score	0.876727 (rank : 18)
Query Neighborhood Hits	112	Target Neighborhood Hits	64	Shared Neighborhood Hits	55
SwissProt Accessions	O95147	Gene names	DUSP14, MKP6
Domain Architecture
Description	Dual specificity protein phosphatase 14 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 6) (MAP kinase phosphatase 6) (MKP-6) (MKP-1-like protein tyrosine phosphatase) (MKP- L).

DUS14_MOUSE
θ value	6.40375e-22 (rank : 18)	NC score	0.878108 (rank : 17)
Query Neighborhood Hits	112	Target Neighborhood Hits	67	Shared Neighborhood Hits	57
SwissProt Accessions	Q9JLY7, Q9D715	Gene names	Dusp14, Mkp6
Domain Architecture
Description	Dual specificity protein phosphatase 14 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 6) (MAP kinase phosphatase 6) (MKP-6).

SSH1_MOUSE
θ value	6.62687e-19 (rank : 19)	NC score	0.776353 (rank : 37)
Query Neighborhood Hits	112	Target Neighborhood Hits	107	Shared Neighborhood Hits	51
SwissProt Accessions	Q76I79, Q3TDG3, Q69ZM4, Q811E5	Gene names	Ssh1, Kiaa1298, Ssh1l
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 1 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-1L) (mSSH-1L).

SSH3_MOUSE
θ value	6.62687e-19 (rank : 20)	NC score	0.796214 (rank : 32)
Query Neighborhood Hits	112	Target Neighborhood Hits	69	Shared Neighborhood Hits	54
SwissProt Accessions	Q8K330, Q3UDX0	Gene names	Ssh3, Ssh3l
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 3 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-3L) (mSSH-3L).

SSH3_HUMAN
θ value	8.65492e-19 (rank : 21)	NC score	0.790445 (rank : 36)
Query Neighborhood Hits	112	Target Neighborhood Hits	75	Shared Neighborhood Hits	51
SwissProt Accessions	Q8TE77, Q6PK42, Q76I75, Q8N9L8, Q8WYL0, Q9NV45, Q9NWZ7	Gene names	SSH3, SSH3L
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 3 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-3L) (hSSH-3L).

SSH2_HUMAN
θ value	4.29542e-18 (rank : 22)	NC score	0.760642 (rank : 41)
Query Neighborhood Hits	112	Target Neighborhood Hits	140	Shared Neighborhood Hits	53
SwissProt Accessions	Q76I76, Q8TDB5, Q8WYL1, Q8WYL2, Q96F40, Q96H36, Q9C0D8	Gene names	SSH2, KIAA1725, SSH2L
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 2 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-2L) (hSSH-2L).

SSH2_MOUSE
θ value	4.29542e-18 (rank : 23)	NC score	0.763095 (rank : 40)
Query Neighborhood Hits	112	Target Neighborhood Hits	119	Shared Neighborhood Hits	53
SwissProt Accessions	Q5SW75, Q3TDK8, Q3TYP8, Q3U2K3, Q5F268, Q5SW74, Q69ZC3, Q76I78	Gene names	Ssh2, Kiaa1725, Ssh2l
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 2 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-2L) (mSSH-2L).

SSH1_HUMAN
θ value	5.60996e-18 (rank : 24)	NC score	0.775344 (rank : 38)
Query Neighborhood Hits	112	Target Neighborhood Hits	164	Shared Neighborhood Hits	55
SwissProt Accessions	Q8WYL5, Q6P6C0, Q8N9A7, Q8WYL3, Q8WYL4, Q9P2P8	Gene names	SSH1, KIAA1298, SSH1L
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 1 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-1L) (hSSH-1L).

DUS21_HUMAN
θ value	1.80466e-16 (rank : 25)	NC score	0.852490 (rank : 25)
Query Neighborhood Hits	112	Target Neighborhood Hits	52	Shared Neighborhood Hits	50
SwissProt Accessions	Q9H596, Q6IAJ6, Q6YDQ8	Gene names	DUSP21, LMWDSP21
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 21 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular weight dual specificity phosphatase 21).

DUS22_MOUSE
θ value	3.07829e-16 (rank : 26)	NC score	0.873039 (rank : 19)
Query Neighborhood Hits	112	Target Neighborhood Hits	57	Shared Neighborhood Hits	56
SwissProt Accessions	Q99N11, Q5SQN9, Q5SQP0	Gene names	Dusp22
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 22 (EC 3.1.3.48) (EC 3.1.3.16) (LMW-DSP2).

DUS22_HUMAN
θ value	6.85773e-16 (rank : 27)	NC score	0.872084 (rank : 20)
Query Neighborhood Hits	112	Target Neighborhood Hits	58	Shared Neighborhood Hits	56
SwissProt Accessions	Q9NRW4, Q59GW2, Q5VWR2, Q96AR1	Gene names	DUSP22, JSP1, MKPX
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 22 (EC 3.1.3.48) (EC 3.1.3.16) (JNK-stimulatory phosphatase-1) (JSP-1) (Mitogen-activated protein kinase phosphatase x) (LMW-DSP2).

DUS18_MOUSE
θ value	1.52774e-15 (rank : 28)	NC score	0.851058 (rank : 27)
Query Neighborhood Hits	112	Target Neighborhood Hits	53	Shared Neighborhood Hits	51
SwissProt Accessions	Q8VE01	Gene names	Dusp18
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 18 (EC 3.1.3.48) (EC 3.1.3.16).

STYX_MOUSE
θ value	1.99529e-15 (rank : 29)	NC score	0.864233 (rank : 24)
Query Neighborhood Hits	112	Target Neighborhood Hits	62	Shared Neighborhood Hits	56
SwissProt Accessions	Q60969, Q3TMA3, Q60970, Q9DCF8	Gene names	Styx
Domain Architecture
Description	Serine/threonine/tyrosine-interacting protein (Protein tyrosine phosphatase-like protein) (Phosphoserine/threonine/tyrosine interaction protein).

DUS18_HUMAN
θ value	2.60593e-15 (rank : 30)	NC score	0.850071 (rank : 28)
Query Neighborhood Hits	112	Target Neighborhood Hits	52	Shared Neighborhood Hits	51
SwissProt Accessions	Q8NEJ0	Gene names	DUSP18, LMWDSP20
Domain Architecture
Description	Dual specificity protein phosphatase 18 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular weight dual specificity phosphatase 20).

STYX_HUMAN
θ value	2.60593e-15 (rank : 31)	NC score	0.865763 (rank : 23)
Query Neighborhood Hits	112	Target Neighborhood Hits	60	Shared Neighborhood Hits	57
SwissProt Accessions	Q8WUJ0, Q99850	Gene names	STYX
Domain Architecture
Description	Serine/threonine/tyrosine-interacting protein (Protein tyrosine phosphatase-like protein).

DUS19_MOUSE
θ value	3.40345e-15 (rank : 32)	NC score	0.865778 (rank : 22)
Query Neighborhood Hits	112	Target Neighborhood Hits	58	Shared Neighborhood Hits	50
SwissProt Accessions	Q8K4T5	Gene names	Dusp19, Skrp1
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 19 (EC 3.1.3.48) (EC 3.1.3.16) (Stress-activated protein kinase pathway-regulating phosphatase 1) (Protein phosphatase SKRP1).

DUS19_HUMAN
θ value	7.58209e-15 (rank : 33)	NC score	0.871165 (rank : 21)
Query Neighborhood Hits	112	Target Neighborhood Hits	52	Shared Neighborhood Hits	51
SwissProt Accessions	Q8WTR2, Q8WYN4	Gene names	DUSP19, DUSP17, SKRP1
Domain Architecture
Description	Dual specificity protein phosphatase 19 (EC 3.1.3.48) (EC 3.1.3.16) (Stress-activated protein kinase pathway-regulating phosphatase 1) (Protein phosphatase SKRP1).

DUS3_HUMAN
θ value	4.16044e-13 (rank : 34)	NC score	0.841578 (rank : 29)
Query Neighborhood Hits	112	Target Neighborhood Hits	58	Shared Neighborhood Hits	52
SwissProt Accessions	P51452	Gene names	DUSP3, VHR
Domain Architecture
Description	Dual specificity protein phosphatase 3 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase VHR).

DUS3_MOUSE
θ value	7.09661e-13 (rank : 35)	NC score	0.840717 (rank : 30)
Query Neighborhood Hits	112	Target Neighborhood Hits	54	Shared Neighborhood Hits	53
SwissProt Accessions	Q9D7X3	Gene names	Dusp3
Domain Architecture
Description	Dual specificity protein phosphatase 3 (EC 3.1.3.48) (EC 3.1.3.16) (T- DSP11).

DUS15_HUMAN
θ value	1.58096e-12 (rank : 36)	NC score	0.851575 (rank : 26)
Query Neighborhood Hits	112	Target Neighborhood Hits	60	Shared Neighborhood Hits	52
SwissProt Accessions	Q9H1R2, Q5QP62, Q5QP63, Q5QP65, Q6PGN7, Q8N826, Q9BX24	Gene names	DUSP15, C20orf57, VHY
Domain Architecture
Description	Dual specificity protein phosphatase 15 (EC 3.1.3.48) (EC 3.1.3.16) (Vaccinia virus VH1-related dual-specific protein phosphatase Y) (VH1- related member Y).

STYL1_HUMAN
θ value	6.00763e-12 (rank : 37)	NC score	0.799497 (rank : 31)
Query Neighborhood Hits	112	Target Neighborhood Hits	43	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Y6J8, Q9UBP1, Q9UK06, Q9UK07, Q9UKG2, Q9UKG3	Gene names	STYXL1, DUSP24, MKSTYX
Domain Architecture
Description	Serine/threonine/tyrosine-interacting-like protein 1 (Dual specificity protein phosphatase 24) (Map kinase phosphatase-like protein MK-STYX) (Dual specificity phosphatase inhibitor MK-STYX).

DUS12_MOUSE
θ value	1.74796e-11 (rank : 38)	NC score	0.793481 (rank : 34)
Query Neighborhood Hits	112	Target Neighborhood Hits	60	Shared Neighborhood Hits	50
SwissProt Accessions	Q9D0T2, Q9EQD3	Gene names	Dusp12
Domain Architecture
Description	Dual specificity protein phosphatase 12 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity phosphatase T-DSP4) (Dual specificity phosphatase VH1).

DUS12_HUMAN
θ value	3.29651e-10 (rank : 39)	NC score	0.774478 (rank : 39)
Query Neighborhood Hits	112	Target Neighborhood Hits	60	Shared Neighborhood Hits	49
SwissProt Accessions	Q9UNI6	Gene names	DUSP12
Domain Architecture
Description	Dual specificity protein phosphatase 12 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity tyrosine phosphatase YVH1).

DUS13_HUMAN
θ value	3.64472e-09 (rank : 40)	NC score	0.792308 (rank : 35)
Query Neighborhood Hits	112	Target Neighborhood Hits	59	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UII6, Q5JSC6, Q96GC2	Gene names	DUSP13, TMDP
Domain Architecture
Description	Dual specificity protein phosphatase 13 (EC 3.1.3.48) (EC 3.1.3.16) (Testis- and skeletal-muscle-specific DSP) (Dual specificity phosphatase SKRP4).

DUS13_MOUSE
θ value	1.38499e-08 (rank : 41)	NC score	0.793852 (rank : 33)
Query Neighborhood Hits	112	Target Neighborhood Hits	56	Shared Neighborhood Hits	49
SwissProt Accessions	Q9QYJ7	Gene names	Dusp13, Tmdp
Domain Architecture
Description	Dual specificity protein phosphatase 13 (EC 3.1.3.48) (EC 3.1.3.16) (Testis- and skeletal muscle-specific DSP) (Dual specificity tyrosine phosphatase TS-DSP6).

PTPM1_MOUSE
θ value	1.09739e-05 (rank : 42)	NC score	0.549008 (rank : 42)
Query Neighborhood Hits	112	Target Neighborhood Hits	64	Shared Neighborhood Hits	61
SwissProt Accessions	Q66GT5, Q9CSJ8, Q9D622	Gene names	Ptpmt1, Plip
Domain Architecture	No domain graphic available
Description	Protein-tyrosine phosphatase mitochondrial 1, mitochondrial precursor (EC 3.1.3.48) (EC 3.1.3.16) (PTEN-like phosphatase) (Phosphoinositide lipid phosphatase).

PTPM1_HUMAN
θ value	3.19293e-05 (rank : 43)	NC score	0.513043 (rank : 43)
Query Neighborhood Hits	112	Target Neighborhood Hits	60	Shared Neighborhood Hits	58
SwissProt Accessions	Q8WUK0, Q7Z557, Q96CR2, Q9BXV8	Gene names	PTPMT1, MOSP, PLIP
Domain Architecture	No domain graphic available
Description	Protein-tyrosine phosphatase mitochondrial 1, mitochondrial precursor (EC 3.1.3.48) (EC 3.1.3.16) (PTEN-like phosphatase) (Phosphoinositide lipid phosphatase).

DUS23_HUMAN
θ value	0.00020696 (rank : 44)	NC score	0.362694 (rank : 44)
Query Neighborhood Hits	112	Target Neighborhood Hits	98	Shared Neighborhood Hits	54
SwissProt Accessions	Q9BVJ7, Q9NX48	Gene names	DUSP23, LDP3, VHZ
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 23 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular mass dual specificity phosphatase 3) (LDP-3) (VH1-like phosphatase Z).

CC14A_HUMAN
θ value	0.000461057 (rank : 45)	NC score	0.295304 (rank : 51)
Query Neighborhood Hits	112	Target Neighborhood Hits	133	Shared Neighborhood Hits	61
SwissProt Accessions	Q9UNH5, O43171, O60727, O60728, Q8IXX0	Gene names	CDC14A
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14A (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog A).

CC14B_HUMAN
θ value	0.000602161 (rank : 46)	NC score	0.352513 (rank : 45)
Query Neighborhood Hits	112	Target Neighborhood Hits	114	Shared Neighborhood Hits	64
SwissProt Accessions	O60729, O43183, O60730	Gene names	CDC14B
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14B (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog B).

DUS23_MOUSE
θ value	0.00102713 (rank : 47)	NC score	0.335756 (rank : 46)
Query Neighborhood Hits	112	Target Neighborhood Hits	94	Shared Neighborhood Hits	52
SwissProt Accessions	Q6NT99, Q9CW48	Gene names	Dusp23, Ldp3
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 23 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular mass dual specificity phosphatase 3) (LDP-3).

EPM2A_HUMAN
θ value	0.00134147 (rank : 48)	NC score	0.308707 (rank : 48)
Query Neighborhood Hits	112	Target Neighborhood Hits	47	Shared Neighborhood Hits	42
SwissProt Accessions	O95278, O95483, Q8IU96, Q8IX24, Q8IX25, Q9BS66, Q9UEN2	Gene names	EPM2A
Domain Architecture	No domain graphic available
Description	Laforin (EC 3.1.3.48) (EC 3.1.3.16) (Lafora PTPase) (LAFPTPase).

CC14A_MOUSE
θ value	0.00390308 (rank : 49)	NC score	0.297709 (rank : 50)
Query Neighborhood Hits	112	Target Neighborhood Hits	117	Shared Neighborhood Hits	60
SwissProt Accessions	Q6GQT0, Q8BZ66	Gene names	Cdc14a
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14A (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog A).

EPM2A_MOUSE
θ value	0.00509761 (rank : 50)	NC score	0.307690 (rank : 49)
Query Neighborhood Hits	112	Target Neighborhood Hits	47	Shared Neighborhood Hits	37
SwissProt Accessions	Q9WUA5, Q8BY80	Gene names	Epm2a
Domain Architecture	No domain graphic available
Description	Laforin (EC 3.1.3.48) (EC 3.1.3.16) (Lafora PTPase) (LAFPTPase).

CC14B_MOUSE
θ value	0.00869519 (rank : 51)	NC score	0.313997 (rank : 47)
Query Neighborhood Hits	112	Target Neighborhood Hits	103	Shared Neighborhood Hits	57
SwissProt Accessions	Q6PFY9, Q80WC4, Q8BLV5	Gene names	Cdc14b
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14B (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog B).

TP4A3_HUMAN
θ value	0.0431538 (rank : 52)	NC score	0.172926 (rank : 52)
Query Neighborhood Hits	112	Target Neighborhood Hits	62	Shared Neighborhood Hits	43
SwissProt Accessions	O75365, Q8IVN5, Q99849, Q9BTW5	Gene names	PTP4A3, PRL3
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a3) (Protein-tyrosine phosphatase of regenerating liver 3) (PRL-3) (PRL-R).

TP4A3_MOUSE
θ value	0.0736092 (rank : 53)	NC score	0.168232 (rank : 53)
Query Neighborhood Hits	112	Target Neighborhood Hits	60	Shared Neighborhood Hits	42
SwissProt Accessions	Q9D658, O70275, Q3T9Z5, Q9CTC8	Gene names	Ptp4a3, Prl3
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a3) (Protein-tyrosine phosphatase of regenerating liver 3) (PRL-3).

TP4A2_HUMAN
θ value	0.125558 (rank : 54)	NC score	0.140217 (rank : 56)
Query Neighborhood Hits	112	Target Neighborhood Hits	56	Shared Neighborhood Hits	31
SwissProt Accessions	Q12974, O00649, Q15197, Q15259, Q15260, Q15261	Gene names	PTP4A2, PRL2, PTPCAAX2
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a2) (Protein-tyrosine phosphatase of regenerating liver 2) (PRL-2) (PTP(CAAXII)) (HU-PP-1) (OV-1).

TP4A2_MOUSE
θ value	0.125558 (rank : 55)	NC score	0.140217 (rank : 57)
Query Neighborhood Hits	112	Target Neighborhood Hits	56	Shared Neighborhood Hits	31
SwissProt Accessions	O70274, Q3U1K7	Gene names	Ptp4a2, Prl2
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a2) (Protein-tyrosine phosphatase of regenerating liver 2) (PRL-2).

ANKS6_MOUSE
θ value	0.163984 (rank : 56)	NC score	0.009377 (rank : 84)
Query Neighborhood Hits	112	Target Neighborhood Hits	435	Shared Neighborhood Hits	7
SwissProt Accessions	Q6GQX6	Gene names	Anks6, Samd6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6).

TTC16_MOUSE
θ value	0.163984 (rank : 57)	NC score	0.029558 (rank : 68)
Query Neighborhood Hits	112	Target Neighborhood Hits	98	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C1F5	Gene names	Ttc16
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 16 (TPR repeat protein 16).

TP4A1_HUMAN
θ value	0.279714 (rank : 58)	NC score	0.142155 (rank : 54)
Query Neighborhood Hits	112	Target Neighborhood Hits	68	Shared Neighborhood Hits	37
SwissProt Accessions	Q93096, O00648, Q49A54	Gene names	PTP4A1, PRL1, PTPCAAX1
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a1) (Protein-tyrosine phosphatase of regenerating liver 1) (PRL-1) (PTP(CAAXI)).

TP4A1_MOUSE
θ value	0.279714 (rank : 59)	NC score	0.142155 (rank : 55)
Query Neighborhood Hits	112	Target Neighborhood Hits	68	Shared Neighborhood Hits	37
SwissProt Accessions	Q63739, O09097, O09154, Q3UFU9	Gene names	Ptp4a1, Prl1
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a1) (Protein-tyrosine phosphatase of regenerating liver 1) (PRL-1).

RECQ4_MOUSE
θ value	0.62314 (rank : 60)	NC score	0.013827 (rank : 74)
Query Neighborhood Hits	112	Target Neighborhood Hits	206	Shared Neighborhood Hits	2
SwissProt Accessions	Q75NR7, Q76MT1, Q99PV9	Gene names	Recql4, Recq4
Domain Architecture	No domain graphic available
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4).

PTPRE_MOUSE
θ value	0.813845 (rank : 61)	NC score	0.024345 (rank : 71)
Query Neighborhood Hits	112	Target Neighborhood Hits	86	Shared Neighborhood Hits	24
SwissProt Accessions	P49446, Q62134, Q62444, Q64496	Gene names	Ptpre, Ptpe
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

DUS11_MOUSE
θ value	1.06291 (rank : 62)	NC score	0.119095 (rank : 58)
Query Neighborhood Hits	112	Target Neighborhood Hits	41	Shared Neighborhood Hits	28
SwissProt Accessions	Q6NXK5, Q8BTR4, Q8BYE4	Gene names	Dusp11, Pir1
Domain Architecture	No domain graphic available
Description	RNA/RNP complex-1-interacting phosphatase (EC 3.1.3.-) (Phosphatase that interacts with RNA/RNP complex 1) (Dual specificity protein phosphatase 11).

CAR10_HUMAN
θ value	1.38821 (rank : 63)	NC score	0.006987 (rank : 93)
Query Neighborhood Hits	112	Target Neighborhood Hits	569	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BWT7, Q14CQ8, Q5TFG6, Q9UGR5, Q9UGR6, Q9Y3H0	Gene names	CARD10, CARMA3
Domain Architecture
Description	Caspase recruitment domain-containing protein 10 (CARD-containing MAGUK protein 3) (Carma 3).

PTPRA_MOUSE
θ value	1.38821 (rank : 64)	NC score	0.026800 (rank : 70)
Query Neighborhood Hits	112	Target Neighborhood Hits	93	Shared Neighborhood Hits	26
SwissProt Accessions	P18052, Q61808	Gene names	Ptpra, Lrp, Ptpa
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (LCA- related phosphatase) (PTPTY-28).

PTPRA_HUMAN
θ value	1.81305 (rank : 65)	NC score	0.024308 (rank : 72)
Query Neighborhood Hits	112	Target Neighborhood Hits	101	Shared Neighborhood Hits	26
SwissProt Accessions	P18433, Q14513, Q7Z2I2, Q96TD9	Gene names	PTPRA, PTPA
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha).

TGON2_HUMAN
θ value	1.81305 (rank : 66)	NC score	0.006144 (rank : 95)
Query Neighborhood Hits	112	Target Neighborhood Hits	1037	Shared Neighborhood Hits	15
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

ZBTB9_MOUSE
θ value	1.81305 (rank : 67)	NC score	-0.000383 (rank : 109)
Query Neighborhood Hits	112	Target Neighborhood Hits	780	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CDC7, Q3U3B2, Q9CYQ0	Gene names	Zbtb9
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 9.

DUS11_HUMAN
θ value	2.36792 (rank : 68)	NC score	0.066894 (rank : 59)
Query Neighborhood Hits	112	Target Neighborhood Hits	37	Shared Neighborhood Hits	20
SwissProt Accessions	O75319, Q6AI47, Q9BWE3	Gene names	DUSP11, PIR1
Domain Architecture
Description	RNA/RNP complex-1-interacting phosphatase (EC 3.1.3.-) (Phosphatase that interacts with RNA/RNP complex 1) (Dual specificity protein phosphatase 11).

MCE1_HUMAN
θ value	2.36792 (rank : 69)	NC score	0.063455 (rank : 60)
Query Neighborhood Hits	112	Target Neighborhood Hits	34	Shared Neighborhood Hits	25
SwissProt Accessions	O60942, O43483, O60257, O60351	Gene names	RNGTT, CAP1A
Domain Architecture
Description	mRNA capping enzyme (HCE) (HCAP1) [Includes: Polynucleotide 5'- triphosphatase (EC 3.1.3.33) (mRNA 5'-triphosphatase) (TPase); mRNA guanylyltransferase (EC 2.7.7.50) (GTP--RNA guanylyltransferase) (GTase)].

MCE1_MOUSE
θ value	2.36792 (rank : 70)	NC score	0.062856 (rank : 61)
Query Neighborhood Hits	112	Target Neighborhood Hits	36	Shared Neighborhood Hits	26
SwissProt Accessions	O55236	Gene names	Rngtt, Cap1a
Domain Architecture
Description	mRNA capping enzyme (HCE) (MCE1) [Includes: Polynucleotide 5'- triphosphatase (EC 3.1.3.33) (mRNA 5'-triphosphatase) (TPase); mRNA guanylyltransferase (EC 2.7.7.50) (GTP--RNA guanylyltransferase) (GTase)].

MTM1_HUMAN
θ value	2.36792 (rank : 71)	NC score	0.033371 (rank : 66)
Query Neighborhood Hits	112	Target Neighborhood Hits	32	Shared Neighborhood Hits	12
SwissProt Accessions	Q13496, Q8NEL1	Gene names	MTM1, CG2
Domain Architecture
Description	Myotubularin (EC 3.1.3.48).

PTPRE_HUMAN
θ value	2.36792 (rank : 72)	NC score	0.027810 (rank : 69)
Query Neighborhood Hits	112	Target Neighborhood Hits	92	Shared Neighborhood Hits	28
SwissProt Accessions	P23469, Q96KQ6	Gene names	PTPRE
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

RIPK3_MOUSE
θ value	2.36792 (rank : 73)	NC score	-0.003188 (rank : 111)
Query Neighborhood Hits	112	Target Neighborhood Hits	867	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QZL0	Gene names	Ripk3, Rip3
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 3 (EC 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) (mRIP3).

SRBS1_MOUSE
θ value	2.36792 (rank : 74)	NC score	0.007655 (rank : 90)
Query Neighborhood Hits	112	Target Neighborhood Hits	409	Shared Neighborhood Hits	7
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

MAP2_MOUSE
θ value	3.0926 (rank : 75)	NC score	0.009872 (rank : 82)
Query Neighborhood Hits	112	Target Neighborhood Hits	342	Shared Neighborhood Hits	5
SwissProt Accessions	P20357	Gene names	Map2, Mtap2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2).

MPP10_MOUSE
θ value	3.0926 (rank : 76)	NC score	0.011422 (rank : 79)
Query Neighborhood Hits	112	Target Neighborhood Hits	251	Shared Neighborhood Hits	4
SwissProt Accessions	Q810V0	Gene names	Mphosph10
Domain Architecture	No domain graphic available
Description	U3 small nucleolar ribonucleoprotein protein MPP10 (M phase phosphoprotein 10).

SRRM2_MOUSE
θ value	3.0926 (rank : 77)	NC score	0.007994 (rank : 88)
Query Neighborhood Hits	112	Target Neighborhood Hits	1470	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

TBCD4_HUMAN
θ value	3.0926 (rank : 78)	NC score	0.007559 (rank : 91)
Query Neighborhood Hits	112	Target Neighborhood Hits	357	Shared Neighborhood Hits	4
SwissProt Accessions	O60343, Q5W0B9	Gene names	TBC1D4, KIAA0603
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 4 (Akt substrate of 160 kDa) (AS160).

E41L2_MOUSE
θ value	4.03905 (rank : 79)	NC score	0.004585 (rank : 100)
Query Neighborhood Hits	112	Target Neighborhood Hits	459	Shared Neighborhood Hits	6
SwissProt Accessions	O70318	Gene names	Epb41l2, Epb4.1l2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

HTF4_MOUSE
θ value	4.03905 (rank : 80)	NC score	0.011650 (rank : 78)
Query Neighborhood Hits	112	Target Neighborhood Hits	153	Shared Neighborhood Hits	6
SwissProt Accessions	Q61286	Gene names	Tcf12, Alf1, Meb
Domain Architecture
Description	Transcription factor 12 (Transcription factor HTF-4) (E-box-binding protein) (DNA-binding protein HTF4) (Class A helix-loop-helix transcription factor ME1).

STK31_MOUSE
θ value	4.03905 (rank : 81)	NC score	0.005762 (rank : 96)
Query Neighborhood Hits	112	Target Neighborhood Hits	474	Shared Neighborhood Hits	3
SwissProt Accessions	Q99MW1	Gene names	Stk31
Domain Architecture
Description	Serine/threonine-protein kinase 31 (EC 2.7.11.1).

SYNE1_HUMAN
θ value	4.03905 (rank : 82)	NC score	0.001186 (rank : 107)
Query Neighborhood Hits	112	Target Neighborhood Hits	1484	Shared Neighborhood Hits	14
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

WTAP_HUMAN
θ value	4.03905 (rank : 83)	NC score	0.013000 (rank : 76)
Query Neighborhood Hits	112	Target Neighborhood Hits	262	Shared Neighborhood Hits	5
SwissProt Accessions	Q15007, Q96T28, Q9BYJ7, Q9H4E2	Gene names	WTAP, KIAA0105
Domain Architecture	No domain graphic available
Description	Wilms' tumor 1-associating protein (WT1-associated protein) (Putative pre-mRNA-splicing regulator female-lethal(2D) homolog).

ZN445_MOUSE
θ value	4.03905 (rank : 84)	NC score	-0.004654 (rank : 112)
Query Neighborhood Hits	112	Target Neighborhood Hits	760	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R2V3, Q8K216	Gene names	Znf445, Zfp445
Domain Architecture
Description	Zinc finger protein 445.

AF9_HUMAN
θ value	5.27518 (rank : 85)	NC score	0.013627 (rank : 75)
Query Neighborhood Hits	112	Target Neighborhood Hits	202	Shared Neighborhood Hits	7
SwissProt Accessions	P42568	Gene names	MLLT3, AF9, YEATS3
Domain Architecture
Description	Protein AF-9 (ALL1 fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) (YEATS domain-containing protein 3).

IREB2_HUMAN
θ value	5.27518 (rank : 86)	NC score	0.007379 (rank : 92)
Query Neighborhood Hits	112	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	P48200, Q13095	Gene names	IREB2
Domain Architecture
Description	Iron-responsive element-binding protein 2 (IRE-BP 2) (Iron regulatory protein 2) (IRP2).

K0196_HUMAN
θ value	5.27518 (rank : 87)	NC score	0.010263 (rank : 81)
Query Neighborhood Hits	112	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	Q12768, Q3KQX5, Q8TBQ2	Gene names	KIAA0196
Domain Architecture	No domain graphic available
Description	Protein KIAA0196.

MTM1_MOUSE
θ value	5.27518 (rank : 88)	NC score	0.032528 (rank : 67)
Query Neighborhood Hits	112	Target Neighborhood Hits	36	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Z2C5	Gene names	Mtm1
Domain Architecture
Description	Myotubularin (EC 3.1.3.48).

NACAM_MOUSE
θ value	5.27518 (rank : 89)	NC score	0.002242 (rank : 105)
Query Neighborhood Hits	112	Target Neighborhood Hits	1866	Shared Neighborhood Hits	16
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

PDZD6_HUMAN
θ value	5.27518 (rank : 90)	NC score	0.013918 (rank : 73)
Query Neighborhood Hits	112	Target Neighborhood Hits	81	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ULD6, Q4W5I8, Q86V55	Gene names	PDZD6, KIAA1284, PDZK6
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 6.

PTN1_MOUSE
θ value	5.27518 (rank : 91)	NC score	0.039589 (rank : 64)
Query Neighborhood Hits	112	Target Neighborhood Hits	85	Shared Neighborhood Hits	25
SwissProt Accessions	P35821, Q60840, Q62131, Q64498, Q99JS1	Gene names	Ptpn1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B) (Protein-protein-tyrosine phosphatase HA2) (PTP-HA2).

RP1L1_HUMAN
θ value	5.27518 (rank : 92)	NC score	0.007720 (rank : 89)
Query Neighborhood Hits	112	Target Neighborhood Hits	1072	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

TIF1G_MOUSE
θ value	5.27518 (rank : 93)	NC score	0.002015 (rank : 106)
Query Neighborhood Hits	112	Target Neighborhood Hits	498	Shared Neighborhood Hits	5
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

TLR3_HUMAN
θ value	5.27518 (rank : 94)	NC score	0.000073 (rank : 108)
Query Neighborhood Hits	112	Target Neighborhood Hits	323	Shared Neighborhood Hits	2
SwissProt Accessions	O15455	Gene names	TLR3
Domain Architecture
Description	Toll-like receptor 3 precursor (CD283 antigen).

AFTIN_MOUSE
θ value	6.88961 (rank : 95)	NC score	0.009041 (rank : 85)
Query Neighborhood Hits	112	Target Neighborhood Hits	52	Shared Neighborhood Hits	3
SwissProt Accessions	Q80WT5, Q5SSE6, Q99KJ1	Gene names	Aftph, Afth
Domain Architecture	No domain graphic available
Description	Aftiphilin.

ANKF1_HUMAN
θ value	6.88961 (rank : 96)	NC score	0.010677 (rank : 80)
Query Neighborhood Hits	112	Target Neighborhood Hits	126	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N957	Gene names	ANKFN1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and fibronectin type-III domain-containing protein 1.

CTTB2_HUMAN
θ value	6.88961 (rank : 97)	NC score	-0.001019 (rank : 110)
Query Neighborhood Hits	112	Target Neighborhood Hits	1061	Shared Neighborhood Hits	9
SwissProt Accessions	Q8WZ74, O43389, Q7LG11, Q9C0A5	Gene names	CTTNBP2, C7orf8, CORTBP2, KIAA1758
Domain Architecture	No domain graphic available
Description	Cortactin-binding protein 2 (CortBP2).

ELF1_MOUSE
θ value	6.88961 (rank : 98)	NC score	0.003543 (rank : 102)
Query Neighborhood Hits	112	Target Neighborhood Hits	139	Shared Neighborhood Hits	4
SwissProt Accessions	Q60775	Gene names	Elf1
Domain Architecture
Description	ETS-related transcription factor Elf-1 (E74-like factor 1).

HTF4_HUMAN
θ value	6.88961 (rank : 99)	NC score	0.009854 (rank : 83)
Query Neighborhood Hits	112	Target Neighborhood Hits	152	Shared Neighborhood Hits	7
SwissProt Accessions	Q99081	Gene names	TCF12, HEB, HTF4
Domain Architecture
Description	Transcription factor 12 (Transcription factor HTF-4) (E-box-binding protein) (DNA-binding protein HTF4).

PTN1_HUMAN
θ value	6.88961 (rank : 100)	NC score	0.039201 (rank : 65)
Query Neighborhood Hits	112	Target Neighborhood Hits	84	Shared Neighborhood Hits	23
SwissProt Accessions	P18031, Q5TGD8, Q9BQV9, Q9NQQ4	Gene names	PTPN1, PTP1B
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B).

RASA2_HUMAN
θ value	6.88961 (rank : 101)	NC score	0.002887 (rank : 104)
Query Neighborhood Hits	112	Target Neighborhood Hits	157	Shared Neighborhood Hits	2
SwissProt Accessions	Q15283, O00695, Q15284, Q92594, Q99577, Q9UEQ2	Gene names	RASA2, GAP1M, RASGAP
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

TCF20_MOUSE
θ value	6.88961 (rank : 102)	NC score	0.005493 (rank : 97)
Query Neighborhood Hits	112	Target Neighborhood Hits	396	Shared Neighborhood Hits	5
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

TOP2B_MOUSE
θ value	6.88961 (rank : 103)	NC score	0.008506 (rank : 86)
Query Neighborhood Hits	112	Target Neighborhood Hits	80	Shared Neighborhood Hits	3
SwissProt Accessions	Q64511, Q7TQG4	Gene names	Top2b
Domain Architecture
Description	DNA topoisomerase 2-beta (EC 5.99.1.3) (DNA topoisomerase II, beta isozyme).

TRPS1_HUMAN
θ value	6.88961 (rank : 104)	NC score	0.003278 (rank : 103)
Query Neighborhood Hits	112	Target Neighborhood Hits	539	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UHF7, Q9NWE1, Q9UHH6	Gene names	TRPS1
Domain Architecture
Description	Zinc finger transcription factor Trps1 (Zinc finger protein GC79) (Tricho-rhino-phalangeal syndrome type I protein).

WTAP_MOUSE
θ value	6.88961 (rank : 105)	NC score	0.011692 (rank : 77)
Query Neighborhood Hits	112	Target Neighborhood Hits	250	Shared Neighborhood Hits	5
SwissProt Accessions	Q9ER69	Gene names	Wtap
Domain Architecture	No domain graphic available
Description	Wilms' tumor 1-associating protein (WT1-associated protein) (Putative pre-mRNA-splicing regulator female-lethal(2D) homolog).

IF4G1_HUMAN
θ value	8.99809 (rank : 106)	NC score	0.003572 (rank : 101)
Query Neighborhood Hits	112	Target Neighborhood Hits	347	Shared Neighborhood Hits	5
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

MUC1_MOUSE
θ value	8.99809 (rank : 107)	NC score	0.005365 (rank : 98)
Query Neighborhood Hits	112	Target Neighborhood Hits	388	Shared Neighborhood Hits	6
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

PALB2_HUMAN
θ value	8.99809 (rank : 108)	NC score	0.006685 (rank : 94)
Query Neighborhood Hits	112	Target Neighborhood Hits	117	Shared Neighborhood Hits	2
SwissProt Accessions	Q86YC2, Q8N7Y6, Q8ND31, Q9H6W1	Gene names	PALB2
Domain Architecture	No domain graphic available
Description	Partner and localizer of BRCA2.

PTEN_HUMAN
θ value	8.99809 (rank : 109)	NC score	0.053614 (rank : 62)
Query Neighborhood Hits	112	Target Neighborhood Hits	72	Shared Neighborhood Hits	34
SwissProt Accessions	P60484, O00633, O02679, Q6ICT7	Gene names	PTEN, MMAC1, TEP1
Domain Architecture
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual- specificity protein phosphatase PTEN (EC 3.1.3.67) (EC 3.1.3.16) (EC 3.1.3.48) (Phosphatase and tensin homolog) (Mutated in multiple advanced cancers 1).

PTEN_MOUSE
θ value	8.99809 (rank : 110)	NC score	0.053614 (rank : 63)
Query Neighborhood Hits	112	Target Neighborhood Hits	73	Shared Neighborhood Hits	34
SwissProt Accessions	O08586, Q542G1	Gene names	Pten, Mmac1
Domain Architecture
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase PTEN (EC 3.1.3.67) (Mutated in multiple advanced cancers 1).

TOP2B_HUMAN
θ value	8.99809 (rank : 111)	NC score	0.008026 (rank : 87)
Query Neighborhood Hits	112	Target Neighborhood Hits	101	Shared Neighborhood Hits	4
SwissProt Accessions	Q02880, Q13600, Q9UMG8, Q9UQP8	Gene names	TOP2B
Domain Architecture
Description	DNA topoisomerase 2-beta (EC 5.99.1.3) (DNA topoisomerase II, beta isozyme).

ZN638_HUMAN
θ value	8.99809 (rank : 112)	NC score	0.005294 (rank : 99)
Query Neighborhood Hits	112	Target Neighborhood Hits	343	Shared Neighborhood Hits	8
SwissProt Accessions	Q14966, Q53R34, Q5XJ05, Q68DP3, Q6P2H2, Q7Z3T7, Q8NF92, Q8TCA1, Q9H2G1, Q9NP37	Gene names	ZNF638, NP220, ZFML
Domain Architecture	No domain graphic available
Description	Zinc finger protein 638 (Nuclear protein 220) (Zinc-finger matrin-like protein) (Cutaneous T-cell lymphoma-associated antigen se33-1) (CTCL tumor antigen se33-1).

Hits sorted by NC score

DUS16_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	112	Target Neighborhood Hits	112	Shared Neighborhood Hits	112
SwissProt Accessions	Q9BY84, Q9C0G3	Gene names	DUSP16, KIAA1700, MKP7
Domain Architecture
Description	Dual specificity protein phosphatase 16 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 7) (MAP kinase phosphatase 7) (MKP-7).

DUS8_MOUSE
NC score	0.975594 (rank : 2)	θ value	5.80223e-132 (rank : 3)
Query Neighborhood Hits	112	Target Neighborhood Hits	119	Shared Neighborhood Hits	61
SwissProt Accessions	O09112	Gene names	Dusp8, Nttp1
Domain Architecture
Description	Dual specificity protein phosphatase 8 (EC 3.1.3.48) (EC 3.1.3.16) (Neuronal tyrosine threonine phosphatase 1).

DUS8_HUMAN
NC score	0.970683 (rank : 3)	θ value	1.4755e-135 (rank : 2)
Query Neighborhood Hits	112	Target Neighborhood Hits	161	Shared Neighborhood Hits	62
SwissProt Accessions	Q13202	Gene names	DUSP8, VH5
Domain Architecture
Description	Dual specificity protein phosphatase 8 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase hVH-5).

DUS10_MOUSE
NC score	0.940942 (rank : 4)	θ value	5.38352e-45 (rank : 5)
Query Neighborhood Hits	112	Target Neighborhood Hits	62	Shared Neighborhood Hits	55
SwissProt Accessions	Q9ESS0, Q9CZY9	Gene names	Dusp10, Mkp5
Domain Architecture
Description	Dual specificity protein phosphatase 10 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 5) (MAP kinase phosphatase 5) (MKP-5).

DUS10_HUMAN
NC score	0.940214 (rank : 5)	θ value	4.122e-45 (rank : 4)
Query Neighborhood Hits	112	Target Neighborhood Hits	64	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Y6W6	Gene names	DUSP10, MKP5
Domain Architecture
Description	Dual specificity protein phosphatase 10 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 5) (MAP kinase phosphatase 5) (MKP-5).

DUS9_HUMAN
NC score	0.939078 (rank : 6)	θ value	3.86705e-35 (rank : 15)
Query Neighborhood Hits	112	Target Neighborhood Hits	59	Shared Neighborhood Hits	55
SwissProt Accessions	Q99956	Gene names	DUSP9, MKP4
Domain Architecture
Description	Dual specificity protein phosphatase 9 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 4) (MAP kinase phosphatase 4) (MKP-4).

DUS2_MOUSE
NC score	0.934961 (rank : 7)	θ value	8.32485e-38 (rank : 14)
Query Neighborhood Hits	112	Target Neighborhood Hits	86	Shared Neighborhood Hits	70
SwissProt Accessions	Q05922, Q60640	Gene names	Dusp2, Pac-1, Pac1
Domain Architecture
Description	Dual specificity protein phosphatase 2 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase PAC-1).

DUS2_HUMAN
NC score	0.933794 (rank : 8)	θ value	6.37413e-38 (rank : 13)
Query Neighborhood Hits	112	Target Neighborhood Hits	67	Shared Neighborhood Hits	61
SwissProt Accessions	Q05923	Gene names	DUSP2, PAC1
Domain Architecture
Description	Dual specificity protein phosphatase 2 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase PAC-1).

DUS7_HUMAN
NC score	0.932721 (rank : 9)	θ value	1.51715e-39 (rank : 11)
Query Neighborhood Hits	112	Target Neighborhood Hits	69	Shared Neighborhood Hits	57
SwissProt Accessions	Q16829, Q8NFJ0	Gene names	DUSP7, PYST2
Domain Architecture
Description	Dual specificity protein phosphatase 7 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase PYST2).

DUS6_HUMAN
NC score	0.930512 (rank : 10)	θ value	3.85808e-43 (rank : 6)
Query Neighborhood Hits	112	Target Neighborhood Hits	57	Shared Neighborhood Hits	52
SwissProt Accessions	Q16828, O75109, Q53Y75, Q9BSH6	Gene names	DUSP6, MKP3, PYST1
Domain Architecture
Description	Dual specificity protein phosphatase 6 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 3) (MAP kinase phosphatase 3) (MKP-3) (Dual specificity protein phosphatase PYST1).

DUS6_MOUSE
NC score	0.930104 (rank : 11)	θ value	1.12253e-42 (rank : 7)
Query Neighborhood Hits	112	Target Neighborhood Hits	57	Shared Neighborhood Hits	52
SwissProt Accessions	Q9DBB1, Q542I5, Q9D7L4	Gene names	Dusp6, Mkp3
Domain Architecture
Description	Dual specificity protein phosphatase 6 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 3) (MAP kinase phosphatase 3) (MKP-3).

DUS1_HUMAN
NC score	0.926228 (rank : 12)	θ value	7.52953e-39 (rank : 12)
Query Neighborhood Hits	112	Target Neighborhood Hits	73	Shared Neighborhood Hits	61
SwissProt Accessions	P28562, Q2V508	Gene names	DUSP1, CL100, MKP1, PTPN10, VH1
Domain Architecture
Description	Dual specificity protein phosphatase 1 (EC 3.1.3.48) (EC 3.1.3.16) (MAP kinase phosphatase 1) (MKP-1) (Protein-tyrosine phosphatase CL100) (Dual specificity protein phosphatase hVH1).

DUS1_MOUSE
NC score	0.925962 (rank : 13)	θ value	1.16164e-39 (rank : 9)
Query Neighborhood Hits	112	Target Neighborhood Hits	72	Shared Neighborhood Hits	62
SwissProt Accessions	P28563	Gene names	Dusp1, 3ch134, Mkp1, Ptpn10, Ptpn16
Domain Architecture
Description	Dual specificity protein phosphatase 1 (EC 3.1.3.48) (EC 3.1.3.16) (MAP kinase phosphatase 1) (MKP-1) (Protein-tyrosine phosphatase 3CH134) (Protein-tyrosine phosphatase ERP).

DUS4_HUMAN
NC score	0.925747 (rank : 14)	θ value	3.99248e-40 (rank : 8)
Query Neighborhood Hits	112	Target Neighborhood Hits	77	Shared Neighborhood Hits	62
SwissProt Accessions	Q13115, Q13524	Gene names	DUSP4, MKP2, VH2
Domain Architecture
Description	Dual specificity protein phosphatase 4 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 2) (MAP kinase phosphatase 2) (MKP-2) (Dual specificity protein phosphatase hVH2).

DUS4_MOUSE
NC score	0.925137 (rank : 15)	θ value	1.16164e-39 (rank : 10)
Query Neighborhood Hits	112	Target Neighborhood Hits	75	Shared Neighborhood Hits	62
SwissProt Accessions	Q8BFV3	Gene names	Dusp4
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 4 (EC 3.1.3.48) (EC 3.1.3.16).

DUS5_HUMAN
NC score	0.924205 (rank : 16)	θ value	9.8567e-31 (rank : 16)
Query Neighborhood Hits	112	Target Neighborhood Hits	82	Shared Neighborhood Hits	61
SwissProt Accessions	Q16690, Q12997	Gene names	DUSP5, VH3
Domain Architecture
Description	Dual specificity protein phosphatase 5 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase hVH3).

DUS14_MOUSE
NC score	0.878108 (rank : 17)	θ value	6.40375e-22 (rank : 18)
Query Neighborhood Hits	112	Target Neighborhood Hits	67	Shared Neighborhood Hits	57
SwissProt Accessions	Q9JLY7, Q9D715	Gene names	Dusp14, Mkp6
Domain Architecture
Description	Dual specificity protein phosphatase 14 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 6) (MAP kinase phosphatase 6) (MKP-6).

DUS14_HUMAN
NC score	0.876727 (rank : 18)	θ value	4.9032e-22 (rank : 17)
Query Neighborhood Hits	112	Target Neighborhood Hits	64	Shared Neighborhood Hits	55
SwissProt Accessions	O95147	Gene names	DUSP14, MKP6
Domain Architecture
Description	Dual specificity protein phosphatase 14 (EC 3.1.3.48) (EC 3.1.3.16) (Mitogen-activated protein kinase phosphatase 6) (MAP kinase phosphatase 6) (MKP-6) (MKP-1-like protein tyrosine phosphatase) (MKP- L).

DUS22_MOUSE
NC score	0.873039 (rank : 19)	θ value	3.07829e-16 (rank : 26)
Query Neighborhood Hits	112	Target Neighborhood Hits	57	Shared Neighborhood Hits	56
SwissProt Accessions	Q99N11, Q5SQN9, Q5SQP0	Gene names	Dusp22
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 22 (EC 3.1.3.48) (EC 3.1.3.16) (LMW-DSP2).

DUS22_HUMAN
NC score	0.872084 (rank : 20)	θ value	6.85773e-16 (rank : 27)
Query Neighborhood Hits	112	Target Neighborhood Hits	58	Shared Neighborhood Hits	56
SwissProt Accessions	Q9NRW4, Q59GW2, Q5VWR2, Q96AR1	Gene names	DUSP22, JSP1, MKPX
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 22 (EC 3.1.3.48) (EC 3.1.3.16) (JNK-stimulatory phosphatase-1) (JSP-1) (Mitogen-activated protein kinase phosphatase x) (LMW-DSP2).

DUS19_HUMAN
NC score	0.871165 (rank : 21)	θ value	7.58209e-15 (rank : 33)
Query Neighborhood Hits	112	Target Neighborhood Hits	52	Shared Neighborhood Hits	51
SwissProt Accessions	Q8WTR2, Q8WYN4	Gene names	DUSP19, DUSP17, SKRP1
Domain Architecture
Description	Dual specificity protein phosphatase 19 (EC 3.1.3.48) (EC 3.1.3.16) (Stress-activated protein kinase pathway-regulating phosphatase 1) (Protein phosphatase SKRP1).

DUS19_MOUSE
NC score	0.865778 (rank : 22)	θ value	3.40345e-15 (rank : 32)
Query Neighborhood Hits	112	Target Neighborhood Hits	58	Shared Neighborhood Hits	50
SwissProt Accessions	Q8K4T5	Gene names	Dusp19, Skrp1
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 19 (EC 3.1.3.48) (EC 3.1.3.16) (Stress-activated protein kinase pathway-regulating phosphatase 1) (Protein phosphatase SKRP1).

STYX_HUMAN
NC score	0.865763 (rank : 23)	θ value	2.60593e-15 (rank : 31)
Query Neighborhood Hits	112	Target Neighborhood Hits	60	Shared Neighborhood Hits	57
SwissProt Accessions	Q8WUJ0, Q99850	Gene names	STYX
Domain Architecture
Description	Serine/threonine/tyrosine-interacting protein (Protein tyrosine phosphatase-like protein).

STYX_MOUSE
NC score	0.864233 (rank : 24)	θ value	1.99529e-15 (rank : 29)
Query Neighborhood Hits	112	Target Neighborhood Hits	62	Shared Neighborhood Hits	56
SwissProt Accessions	Q60969, Q3TMA3, Q60970, Q9DCF8	Gene names	Styx
Domain Architecture
Description	Serine/threonine/tyrosine-interacting protein (Protein tyrosine phosphatase-like protein) (Phosphoserine/threonine/tyrosine interaction protein).

DUS21_HUMAN
NC score	0.852490 (rank : 25)	θ value	1.80466e-16 (rank : 25)
Query Neighborhood Hits	112	Target Neighborhood Hits	52	Shared Neighborhood Hits	50
SwissProt Accessions	Q9H596, Q6IAJ6, Q6YDQ8	Gene names	DUSP21, LMWDSP21
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 21 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular weight dual specificity phosphatase 21).

DUS15_HUMAN
NC score	0.851575 (rank : 26)	θ value	1.58096e-12 (rank : 36)
Query Neighborhood Hits	112	Target Neighborhood Hits	60	Shared Neighborhood Hits	52
SwissProt Accessions	Q9H1R2, Q5QP62, Q5QP63, Q5QP65, Q6PGN7, Q8N826, Q9BX24	Gene names	DUSP15, C20orf57, VHY
Domain Architecture
Description	Dual specificity protein phosphatase 15 (EC 3.1.3.48) (EC 3.1.3.16) (Vaccinia virus VH1-related dual-specific protein phosphatase Y) (VH1- related member Y).

DUS18_MOUSE
NC score	0.851058 (rank : 27)	θ value	1.52774e-15 (rank : 28)
Query Neighborhood Hits	112	Target Neighborhood Hits	53	Shared Neighborhood Hits	51
SwissProt Accessions	Q8VE01	Gene names	Dusp18
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 18 (EC 3.1.3.48) (EC 3.1.3.16).

DUS18_HUMAN
NC score	0.850071 (rank : 28)	θ value	2.60593e-15 (rank : 30)
Query Neighborhood Hits	112	Target Neighborhood Hits	52	Shared Neighborhood Hits	51
SwissProt Accessions	Q8NEJ0	Gene names	DUSP18, LMWDSP20
Domain Architecture
Description	Dual specificity protein phosphatase 18 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular weight dual specificity phosphatase 20).

DUS3_HUMAN
NC score	0.841578 (rank : 29)	θ value	4.16044e-13 (rank : 34)
Query Neighborhood Hits	112	Target Neighborhood Hits	58	Shared Neighborhood Hits	52
SwissProt Accessions	P51452	Gene names	DUSP3, VHR
Domain Architecture
Description	Dual specificity protein phosphatase 3 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity protein phosphatase VHR).

DUS3_MOUSE
NC score	0.840717 (rank : 30)	θ value	7.09661e-13 (rank : 35)
Query Neighborhood Hits	112	Target Neighborhood Hits	54	Shared Neighborhood Hits	53
SwissProt Accessions	Q9D7X3	Gene names	Dusp3
Domain Architecture
Description	Dual specificity protein phosphatase 3 (EC 3.1.3.48) (EC 3.1.3.16) (T- DSP11).

STYL1_HUMAN
NC score	0.799497 (rank : 31)	θ value	6.00763e-12 (rank : 37)
Query Neighborhood Hits	112	Target Neighborhood Hits	43	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Y6J8, Q9UBP1, Q9UK06, Q9UK07, Q9UKG2, Q9UKG3	Gene names	STYXL1, DUSP24, MKSTYX
Domain Architecture
Description	Serine/threonine/tyrosine-interacting-like protein 1 (Dual specificity protein phosphatase 24) (Map kinase phosphatase-like protein MK-STYX) (Dual specificity phosphatase inhibitor MK-STYX).

SSH3_MOUSE
NC score	0.796214 (rank : 32)	θ value	6.62687e-19 (rank : 20)
Query Neighborhood Hits	112	Target Neighborhood Hits	69	Shared Neighborhood Hits	54
SwissProt Accessions	Q8K330, Q3UDX0	Gene names	Ssh3, Ssh3l
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 3 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-3L) (mSSH-3L).

DUS13_MOUSE
NC score	0.793852 (rank : 33)	θ value	1.38499e-08 (rank : 41)
Query Neighborhood Hits	112	Target Neighborhood Hits	56	Shared Neighborhood Hits	49
SwissProt Accessions	Q9QYJ7	Gene names	Dusp13, Tmdp
Domain Architecture
Description	Dual specificity protein phosphatase 13 (EC 3.1.3.48) (EC 3.1.3.16) (Testis- and skeletal muscle-specific DSP) (Dual specificity tyrosine phosphatase TS-DSP6).

DUS12_MOUSE
NC score	0.793481 (rank : 34)	θ value	1.74796e-11 (rank : 38)
Query Neighborhood Hits	112	Target Neighborhood Hits	60	Shared Neighborhood Hits	50
SwissProt Accessions	Q9D0T2, Q9EQD3	Gene names	Dusp12
Domain Architecture
Description	Dual specificity protein phosphatase 12 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity phosphatase T-DSP4) (Dual specificity phosphatase VH1).

DUS13_HUMAN
NC score	0.792308 (rank : 35)	θ value	3.64472e-09 (rank : 40)
Query Neighborhood Hits	112	Target Neighborhood Hits	59	Shared Neighborhood Hits	47
SwissProt Accessions	Q9UII6, Q5JSC6, Q96GC2	Gene names	DUSP13, TMDP
Domain Architecture
Description	Dual specificity protein phosphatase 13 (EC 3.1.3.48) (EC 3.1.3.16) (Testis- and skeletal-muscle-specific DSP) (Dual specificity phosphatase SKRP4).

SSH3_HUMAN
NC score	0.790445 (rank : 36)	θ value	8.65492e-19 (rank : 21)
Query Neighborhood Hits	112	Target Neighborhood Hits	75	Shared Neighborhood Hits	51
SwissProt Accessions	Q8TE77, Q6PK42, Q76I75, Q8N9L8, Q8WYL0, Q9NV45, Q9NWZ7	Gene names	SSH3, SSH3L
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 3 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-3L) (hSSH-3L).

SSH1_MOUSE
NC score	0.776353 (rank : 37)	θ value	6.62687e-19 (rank : 19)
Query Neighborhood Hits	112	Target Neighborhood Hits	107	Shared Neighborhood Hits	51
SwissProt Accessions	Q76I79, Q3TDG3, Q69ZM4, Q811E5	Gene names	Ssh1, Kiaa1298, Ssh1l
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 1 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-1L) (mSSH-1L).

SSH1_HUMAN
NC score	0.775344 (rank : 38)	θ value	5.60996e-18 (rank : 24)
Query Neighborhood Hits	112	Target Neighborhood Hits	164	Shared Neighborhood Hits	55
SwissProt Accessions	Q8WYL5, Q6P6C0, Q8N9A7, Q8WYL3, Q8WYL4, Q9P2P8	Gene names	SSH1, KIAA1298, SSH1L
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 1 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-1L) (hSSH-1L).

DUS12_HUMAN
NC score	0.774478 (rank : 39)	θ value	3.29651e-10 (rank : 39)
Query Neighborhood Hits	112	Target Neighborhood Hits	60	Shared Neighborhood Hits	49
SwissProt Accessions	Q9UNI6	Gene names	DUSP12
Domain Architecture
Description	Dual specificity protein phosphatase 12 (EC 3.1.3.48) (EC 3.1.3.16) (Dual specificity tyrosine phosphatase YVH1).

SSH2_MOUSE
NC score	0.763095 (rank : 40)	θ value	4.29542e-18 (rank : 23)
Query Neighborhood Hits	112	Target Neighborhood Hits	119	Shared Neighborhood Hits	53
SwissProt Accessions	Q5SW75, Q3TDK8, Q3TYP8, Q3U2K3, Q5F268, Q5SW74, Q69ZC3, Q76I78	Gene names	Ssh2, Kiaa1725, Ssh2l
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 2 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-2L) (mSSH-2L).

SSH2_HUMAN
NC score	0.760642 (rank : 41)	θ value	4.29542e-18 (rank : 22)
Query Neighborhood Hits	112	Target Neighborhood Hits	140	Shared Neighborhood Hits	53
SwissProt Accessions	Q76I76, Q8TDB5, Q8WYL1, Q8WYL2, Q96F40, Q96H36, Q9C0D8	Gene names	SSH2, KIAA1725, SSH2L
Domain Architecture	No domain graphic available
Description	Protein phosphatase Slingshot homolog 2 (EC 3.1.3.48) (EC 3.1.3.16) (SSH-2L) (hSSH-2L).

PTPM1_MOUSE
NC score	0.549008 (rank : 42)	θ value	1.09739e-05 (rank : 42)
Query Neighborhood Hits	112	Target Neighborhood Hits	64	Shared Neighborhood Hits	61
SwissProt Accessions	Q66GT5, Q9CSJ8, Q9D622	Gene names	Ptpmt1, Plip
Domain Architecture	No domain graphic available
Description	Protein-tyrosine phosphatase mitochondrial 1, mitochondrial precursor (EC 3.1.3.48) (EC 3.1.3.16) (PTEN-like phosphatase) (Phosphoinositide lipid phosphatase).

PTPM1_HUMAN
NC score	0.513043 (rank : 43)	θ value	3.19293e-05 (rank : 43)
Query Neighborhood Hits	112	Target Neighborhood Hits	60	Shared Neighborhood Hits	58
SwissProt Accessions	Q8WUK0, Q7Z557, Q96CR2, Q9BXV8	Gene names	PTPMT1, MOSP, PLIP
Domain Architecture	No domain graphic available
Description	Protein-tyrosine phosphatase mitochondrial 1, mitochondrial precursor (EC 3.1.3.48) (EC 3.1.3.16) (PTEN-like phosphatase) (Phosphoinositide lipid phosphatase).

DUS23_HUMAN
NC score	0.362694 (rank : 44)	θ value	0.00020696 (rank : 44)
Query Neighborhood Hits	112	Target Neighborhood Hits	98	Shared Neighborhood Hits	54
SwissProt Accessions	Q9BVJ7, Q9NX48	Gene names	DUSP23, LDP3, VHZ
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 23 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular mass dual specificity phosphatase 3) (LDP-3) (VH1-like phosphatase Z).

CC14B_HUMAN
NC score	0.352513 (rank : 45)	θ value	0.000602161 (rank : 46)
Query Neighborhood Hits	112	Target Neighborhood Hits	114	Shared Neighborhood Hits	64
SwissProt Accessions	O60729, O43183, O60730	Gene names	CDC14B
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14B (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog B).

DUS23_MOUSE
NC score	0.335756 (rank : 46)	θ value	0.00102713 (rank : 47)
Query Neighborhood Hits	112	Target Neighborhood Hits	94	Shared Neighborhood Hits	52
SwissProt Accessions	Q6NT99, Q9CW48	Gene names	Dusp23, Ldp3
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase 23 (EC 3.1.3.48) (EC 3.1.3.16) (Low molecular mass dual specificity phosphatase 3) (LDP-3).

CC14B_MOUSE
NC score	0.313997 (rank : 47)	θ value	0.00869519 (rank : 51)
Query Neighborhood Hits	112	Target Neighborhood Hits	103	Shared Neighborhood Hits	57
SwissProt Accessions	Q6PFY9, Q80WC4, Q8BLV5	Gene names	Cdc14b
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14B (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog B).

EPM2A_HUMAN
NC score	0.308707 (rank : 48)	θ value	0.00134147 (rank : 48)
Query Neighborhood Hits	112	Target Neighborhood Hits	47	Shared Neighborhood Hits	42
SwissProt Accessions	O95278, O95483, Q8IU96, Q8IX24, Q8IX25, Q9BS66, Q9UEN2	Gene names	EPM2A
Domain Architecture	No domain graphic available
Description	Laforin (EC 3.1.3.48) (EC 3.1.3.16) (Lafora PTPase) (LAFPTPase).

EPM2A_MOUSE
NC score	0.307690 (rank : 49)	θ value	0.00509761 (rank : 50)
Query Neighborhood Hits	112	Target Neighborhood Hits	47	Shared Neighborhood Hits	37
SwissProt Accessions	Q9WUA5, Q8BY80	Gene names	Epm2a
Domain Architecture	No domain graphic available
Description	Laforin (EC 3.1.3.48) (EC 3.1.3.16) (Lafora PTPase) (LAFPTPase).

CC14A_MOUSE
NC score	0.297709 (rank : 50)	θ value	0.00390308 (rank : 49)
Query Neighborhood Hits	112	Target Neighborhood Hits	117	Shared Neighborhood Hits	60
SwissProt Accessions	Q6GQT0, Q8BZ66	Gene names	Cdc14a
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14A (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog A).

CC14A_HUMAN
NC score	0.295304 (rank : 51)	θ value	0.000461057 (rank : 45)
Query Neighborhood Hits	112	Target Neighborhood Hits	133	Shared Neighborhood Hits	61
SwissProt Accessions	Q9UNH5, O43171, O60727, O60728, Q8IXX0	Gene names	CDC14A
Domain Architecture	No domain graphic available
Description	Dual specificity protein phosphatase CDC14A (EC 3.1.3.48) (EC 3.1.3.16) (CDC14 cell division cycle 14 homolog A).

TP4A3_HUMAN
NC score	0.172926 (rank : 52)	θ value	0.0431538 (rank : 52)
Query Neighborhood Hits	112	Target Neighborhood Hits	62	Shared Neighborhood Hits	43
SwissProt Accessions	O75365, Q8IVN5, Q99849, Q9BTW5	Gene names	PTP4A3, PRL3
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a3) (Protein-tyrosine phosphatase of regenerating liver 3) (PRL-3) (PRL-R).

TP4A3_MOUSE
NC score	0.168232 (rank : 53)	θ value	0.0736092 (rank : 53)
Query Neighborhood Hits	112	Target Neighborhood Hits	60	Shared Neighborhood Hits	42
SwissProt Accessions	Q9D658, O70275, Q3T9Z5, Q9CTC8	Gene names	Ptp4a3, Prl3
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a3) (Protein-tyrosine phosphatase of regenerating liver 3) (PRL-3).

TP4A1_HUMAN
NC score	0.142155 (rank : 54)	θ value	0.279714 (rank : 58)
Query Neighborhood Hits	112	Target Neighborhood Hits	68	Shared Neighborhood Hits	37
SwissProt Accessions	Q93096, O00648, Q49A54	Gene names	PTP4A1, PRL1, PTPCAAX1
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a1) (Protein-tyrosine phosphatase of regenerating liver 1) (PRL-1) (PTP(CAAXI)).

TP4A1_MOUSE
NC score	0.142155 (rank : 55)	θ value	0.279714 (rank : 59)
Query Neighborhood Hits	112	Target Neighborhood Hits	68	Shared Neighborhood Hits	37
SwissProt Accessions	Q63739, O09097, O09154, Q3UFU9	Gene names	Ptp4a1, Prl1
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a1) (Protein-tyrosine phosphatase of regenerating liver 1) (PRL-1).

TP4A2_HUMAN
NC score	0.140217 (rank : 56)	θ value	0.125558 (rank : 54)
Query Neighborhood Hits	112	Target Neighborhood Hits	56	Shared Neighborhood Hits	31
SwissProt Accessions	Q12974, O00649, Q15197, Q15259, Q15260, Q15261	Gene names	PTP4A2, PRL2, PTPCAAX2
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a2) (Protein-tyrosine phosphatase of regenerating liver 2) (PRL-2) (PTP(CAAXII)) (HU-PP-1) (OV-1).

TP4A2_MOUSE
NC score	0.140217 (rank : 57)	θ value	0.125558 (rank : 55)
Query Neighborhood Hits	112	Target Neighborhood Hits	56	Shared Neighborhood Hits	31
SwissProt Accessions	O70274, Q3U1K7	Gene names	Ptp4a2, Prl2
Domain Architecture	No domain graphic available
Description	Protein tyrosine phosphatase type IVA protein 2 (EC 3.1.3.48) (Protein-tyrosine phosphatase 4a2) (Protein-tyrosine phosphatase of regenerating liver 2) (PRL-2).

DUS11_MOUSE
NC score	0.119095 (rank : 58)	θ value	1.06291 (rank : 62)
Query Neighborhood Hits	112	Target Neighborhood Hits	41	Shared Neighborhood Hits	28
SwissProt Accessions	Q6NXK5, Q8BTR4, Q8BYE4	Gene names	Dusp11, Pir1
Domain Architecture	No domain graphic available
Description	RNA/RNP complex-1-interacting phosphatase (EC 3.1.3.-) (Phosphatase that interacts with RNA/RNP complex 1) (Dual specificity protein phosphatase 11).

DUS11_HUMAN
NC score	0.066894 (rank : 59)	θ value	2.36792 (rank : 68)
Query Neighborhood Hits	112	Target Neighborhood Hits	37	Shared Neighborhood Hits	20
SwissProt Accessions	O75319, Q6AI47, Q9BWE3	Gene names	DUSP11, PIR1
Domain Architecture
Description	RNA/RNP complex-1-interacting phosphatase (EC 3.1.3.-) (Phosphatase that interacts with RNA/RNP complex 1) (Dual specificity protein phosphatase 11).

MCE1_HUMAN
NC score	0.063455 (rank : 60)	θ value	2.36792 (rank : 69)
Query Neighborhood Hits	112	Target Neighborhood Hits	34	Shared Neighborhood Hits	25
SwissProt Accessions	O60942, O43483, O60257, O60351	Gene names	RNGTT, CAP1A
Domain Architecture
Description	mRNA capping enzyme (HCE) (HCAP1) [Includes: Polynucleotide 5'- triphosphatase (EC 3.1.3.33) (mRNA 5'-triphosphatase) (TPase); mRNA guanylyltransferase (EC 2.7.7.50) (GTP--RNA guanylyltransferase) (GTase)].

MCE1_MOUSE
NC score	0.062856 (rank : 61)	θ value	2.36792 (rank : 70)
Query Neighborhood Hits	112	Target Neighborhood Hits	36	Shared Neighborhood Hits	26
SwissProt Accessions	O55236	Gene names	Rngtt, Cap1a
Domain Architecture
Description	mRNA capping enzyme (HCE) (MCE1) [Includes: Polynucleotide 5'- triphosphatase (EC 3.1.3.33) (mRNA 5'-triphosphatase) (TPase); mRNA guanylyltransferase (EC 2.7.7.50) (GTP--RNA guanylyltransferase) (GTase)].

PTEN_HUMAN
NC score	0.053614 (rank : 62)	θ value	8.99809 (rank : 109)
Query Neighborhood Hits	112	Target Neighborhood Hits	72	Shared Neighborhood Hits	34
SwissProt Accessions	P60484, O00633, O02679, Q6ICT7	Gene names	PTEN, MMAC1, TEP1
Domain Architecture
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual- specificity protein phosphatase PTEN (EC 3.1.3.67) (EC 3.1.3.16) (EC 3.1.3.48) (Phosphatase and tensin homolog) (Mutated in multiple advanced cancers 1).

PTEN_MOUSE
NC score	0.053614 (rank : 63)	θ value	8.99809 (rank : 110)
Query Neighborhood Hits	112	Target Neighborhood Hits	73	Shared Neighborhood Hits	34
SwissProt Accessions	O08586, Q542G1	Gene names	Pten, Mmac1
Domain Architecture
Description	Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase PTEN (EC 3.1.3.67) (Mutated in multiple advanced cancers 1).

PTN1_MOUSE
NC score	0.039589 (rank : 64)	θ value	5.27518 (rank : 91)
Query Neighborhood Hits	112	Target Neighborhood Hits	85	Shared Neighborhood Hits	25
SwissProt Accessions	P35821, Q60840, Q62131, Q64498, Q99JS1	Gene names	Ptpn1
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B) (Protein-protein-tyrosine phosphatase HA2) (PTP-HA2).

PTN1_HUMAN
NC score	0.039201 (rank : 65)	θ value	6.88961 (rank : 100)
Query Neighborhood Hits	112	Target Neighborhood Hits	84	Shared Neighborhood Hits	23
SwissProt Accessions	P18031, Q5TGD8, Q9BQV9, Q9NQQ4	Gene names	PTPN1, PTP1B
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 1 (EC 3.1.3.48) (Protein-tyrosine phosphatase 1B) (PTP-1B).

MTM1_HUMAN
NC score	0.033371 (rank : 66)	θ value	2.36792 (rank : 71)
Query Neighborhood Hits	112	Target Neighborhood Hits	32	Shared Neighborhood Hits	12
SwissProt Accessions	Q13496, Q8NEL1	Gene names	MTM1, CG2
Domain Architecture
Description	Myotubularin (EC 3.1.3.48).

MTM1_MOUSE
NC score	0.032528 (rank : 67)	θ value	5.27518 (rank : 88)
Query Neighborhood Hits	112	Target Neighborhood Hits	36	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Z2C5	Gene names	Mtm1
Domain Architecture
Description	Myotubularin (EC 3.1.3.48).

TTC16_MOUSE
NC score	0.029558 (rank : 68)	θ value	0.163984 (rank : 57)
Query Neighborhood Hits	112	Target Neighborhood Hits	98	Shared Neighborhood Hits	3
SwissProt Accessions	Q8C1F5	Gene names	Ttc16
Domain Architecture	No domain graphic available
Description	Tetratricopeptide repeat protein 16 (TPR repeat protein 16).

PTPRE_HUMAN
NC score	0.027810 (rank : 69)	θ value	2.36792 (rank : 72)
Query Neighborhood Hits	112	Target Neighborhood Hits	92	Shared Neighborhood Hits	28
SwissProt Accessions	P23469, Q96KQ6	Gene names	PTPRE
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTPRA_MOUSE
NC score	0.026800 (rank : 70)	θ value	1.38821 (rank : 64)
Query Neighborhood Hits	112	Target Neighborhood Hits	93	Shared Neighborhood Hits	26
SwissProt Accessions	P18052, Q61808	Gene names	Ptpra, Lrp, Ptpa
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha) (LCA- related phosphatase) (PTPTY-28).

PTPRE_MOUSE
NC score	0.024345 (rank : 71)	θ value	0.813845 (rank : 61)
Query Neighborhood Hits	112	Target Neighborhood Hits	86	Shared Neighborhood Hits	24
SwissProt Accessions	P49446, Q62134, Q62444, Q64496	Gene names	Ptpre, Ptpe
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase epsilon precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase epsilon) (R-PTP-epsilon).

PTPRA_HUMAN
NC score	0.024308 (rank : 72)	θ value	1.81305 (rank : 65)
Query Neighborhood Hits	112	Target Neighborhood Hits	101	Shared Neighborhood Hits	26
SwissProt Accessions	P18433, Q14513, Q7Z2I2, Q96TD9	Gene names	PTPRA, PTPA
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase alpha precursor (EC 3.1.3.48) (Protein-tyrosine phosphatase alpha) (R-PTP-alpha).

PDZD6_HUMAN
NC score	0.013918 (rank : 73)	θ value	5.27518 (rank : 90)
Query Neighborhood Hits	112	Target Neighborhood Hits	81	Shared Neighborhood Hits	2
SwissProt Accessions	Q9ULD6, Q4W5I8, Q86V55	Gene names	PDZD6, KIAA1284, PDZK6
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 6.

RECQ4_MOUSE
NC score	0.013827 (rank : 74)	θ value	0.62314 (rank : 60)
Query Neighborhood Hits	112	Target Neighborhood Hits	206	Shared Neighborhood Hits	2
SwissProt Accessions	Q75NR7, Q76MT1, Q99PV9	Gene names	Recql4, Recq4
Domain Architecture	No domain graphic available
Description	ATP-dependent DNA helicase Q4 (EC 3.6.1.-) (RecQ protein-like 4).

AF9_HUMAN
NC score	0.013627 (rank : 75)	θ value	5.27518 (rank : 85)
Query Neighborhood Hits	112	Target Neighborhood Hits	202	Shared Neighborhood Hits	7
SwissProt Accessions	P42568	Gene names	MLLT3, AF9, YEATS3
Domain Architecture
Description	Protein AF-9 (ALL1 fused gene from chromosome 9 protein) (Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein) (YEATS domain-containing protein 3).

WTAP_HUMAN
NC score	0.013000 (rank : 76)	θ value	4.03905 (rank : 83)
Query Neighborhood Hits	112	Target Neighborhood Hits	262	Shared Neighborhood Hits	5
SwissProt Accessions	Q15007, Q96T28, Q9BYJ7, Q9H4E2	Gene names	WTAP, KIAA0105
Domain Architecture	No domain graphic available
Description	Wilms' tumor 1-associating protein (WT1-associated protein) (Putative pre-mRNA-splicing regulator female-lethal(2D) homolog).

WTAP_MOUSE
NC score	0.011692 (rank : 77)	θ value	6.88961 (rank : 105)
Query Neighborhood Hits	112	Target Neighborhood Hits	250	Shared Neighborhood Hits	5
SwissProt Accessions	Q9ER69	Gene names	Wtap
Domain Architecture	No domain graphic available
Description	Wilms' tumor 1-associating protein (WT1-associated protein) (Putative pre-mRNA-splicing regulator female-lethal(2D) homolog).

HTF4_MOUSE
NC score	0.011650 (rank : 78)	θ value	4.03905 (rank : 80)
Query Neighborhood Hits	112	Target Neighborhood Hits	153	Shared Neighborhood Hits	6
SwissProt Accessions	Q61286	Gene names	Tcf12, Alf1, Meb
Domain Architecture
Description	Transcription factor 12 (Transcription factor HTF-4) (E-box-binding protein) (DNA-binding protein HTF4) (Class A helix-loop-helix transcription factor ME1).

MPP10_MOUSE
NC score	0.011422 (rank : 79)	θ value	3.0926 (rank : 76)
Query Neighborhood Hits	112	Target Neighborhood Hits	251	Shared Neighborhood Hits	4
SwissProt Accessions	Q810V0	Gene names	Mphosph10
Domain Architecture	No domain graphic available
Description	U3 small nucleolar ribonucleoprotein protein MPP10 (M phase phosphoprotein 10).

ANKF1_HUMAN
NC score	0.010677 (rank : 80)	θ value	6.88961 (rank : 96)
Query Neighborhood Hits	112	Target Neighborhood Hits	126	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N957	Gene names	ANKFN1
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and fibronectin type-III domain-containing protein 1.

K0196_HUMAN
NC score	0.010263 (rank : 81)	θ value	5.27518 (rank : 87)
Query Neighborhood Hits	112	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	Q12768, Q3KQX5, Q8TBQ2	Gene names	KIAA0196
Domain Architecture	No domain graphic available
Description	Protein KIAA0196.

MAP2_MOUSE
NC score	0.009872 (rank : 82)	θ value	3.0926 (rank : 75)
Query Neighborhood Hits	112	Target Neighborhood Hits	342	Shared Neighborhood Hits	5
SwissProt Accessions	P20357	Gene names	Map2, Mtap2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2).

HTF4_HUMAN
NC score	0.009854 (rank : 83)	θ value	6.88961 (rank : 99)
Query Neighborhood Hits	112	Target Neighborhood Hits	152	Shared Neighborhood Hits	7
SwissProt Accessions	Q99081	Gene names	TCF12, HEB, HTF4
Domain Architecture
Description	Transcription factor 12 (Transcription factor HTF-4) (E-box-binding protein) (DNA-binding protein HTF4).

ANKS6_MOUSE
NC score	0.009377 (rank : 84)	θ value	0.163984 (rank : 56)
Query Neighborhood Hits	112	Target Neighborhood Hits	435	Shared Neighborhood Hits	7
SwissProt Accessions	Q6GQX6	Gene names	Anks6, Samd6
Domain Architecture	No domain graphic available
Description	Ankyrin repeat and SAM domain-containing protein 6 (Sterile alpha motif domain-containing protein 6).

AFTIN_MOUSE
NC score	0.009041 (rank : 85)	θ value	6.88961 (rank : 95)
Query Neighborhood Hits	112	Target Neighborhood Hits	52	Shared Neighborhood Hits	3
SwissProt Accessions	Q80WT5, Q5SSE6, Q99KJ1	Gene names	Aftph, Afth
Domain Architecture	No domain graphic available
Description	Aftiphilin.

TOP2B_MOUSE
NC score	0.008506 (rank : 86)	θ value	6.88961 (rank : 103)
Query Neighborhood Hits	112	Target Neighborhood Hits	80	Shared Neighborhood Hits	3
SwissProt Accessions	Q64511, Q7TQG4	Gene names	Top2b
Domain Architecture
Description	DNA topoisomerase 2-beta (EC 5.99.1.3) (DNA topoisomerase II, beta isozyme).

TOP2B_HUMAN
NC score	0.008026 (rank : 87)	θ value	8.99809 (rank : 111)
Query Neighborhood Hits	112	Target Neighborhood Hits	101	Shared Neighborhood Hits	4
SwissProt Accessions	Q02880, Q13600, Q9UMG8, Q9UQP8	Gene names	TOP2B
Domain Architecture
Description	DNA topoisomerase 2-beta (EC 5.99.1.3) (DNA topoisomerase II, beta isozyme).

SRRM2_MOUSE
NC score	0.007994 (rank : 88)	θ value	3.0926 (rank : 77)
Query Neighborhood Hits	112	Target Neighborhood Hits	1470	Shared Neighborhood Hits	17
SwissProt Accessions	Q8BTI8, Q3TBY5, Q569P9, Q80U37, Q8K383	Gene names	Srrm2, Kiaa0324
Domain Architecture	No domain graphic available
Description	Serine/arginine repetitive matrix protein 2.

RP1L1_HUMAN
NC score	0.007720 (rank : 89)	θ value	5.27518 (rank : 92)
Query Neighborhood Hits	112	Target Neighborhood Hits	1072	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

SRBS1_MOUSE
NC score	0.007655 (rank : 90)	θ value	2.36792 (rank : 74)
Query Neighborhood Hits	112	Target Neighborhood Hits	409	Shared Neighborhood Hits	7
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

TBCD4_HUMAN
NC score	0.007559 (rank : 91)	θ value	3.0926 (rank : 78)
Query Neighborhood Hits	112	Target Neighborhood Hits	357	Shared Neighborhood Hits	4
SwissProt Accessions	O60343, Q5W0B9	Gene names	TBC1D4, KIAA0603
Domain Architecture	No domain graphic available
Description	TBC1 domain family member 4 (Akt substrate of 160 kDa) (AS160).

IREB2_HUMAN
NC score	0.007379 (rank : 92)	θ value	5.27518 (rank : 86)
Query Neighborhood Hits	112	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	P48200, Q13095	Gene names	IREB2
Domain Architecture
Description	Iron-responsive element-binding protein 2 (IRE-BP 2) (Iron regulatory protein 2) (IRP2).

CAR10_HUMAN
NC score	0.006987 (rank : 93)	θ value	1.38821 (rank : 63)
Query Neighborhood Hits	112	Target Neighborhood Hits	569	Shared Neighborhood Hits	4
SwissProt Accessions	Q9BWT7, Q14CQ8, Q5TFG6, Q9UGR5, Q9UGR6, Q9Y3H0	Gene names	CARD10, CARMA3
Domain Architecture
Description	Caspase recruitment domain-containing protein 10 (CARD-containing MAGUK protein 3) (Carma 3).

PALB2_HUMAN
NC score	0.006685 (rank : 94)	θ value	8.99809 (rank : 108)
Query Neighborhood Hits	112	Target Neighborhood Hits	117	Shared Neighborhood Hits	2
SwissProt Accessions	Q86YC2, Q8N7Y6, Q8ND31, Q9H6W1	Gene names	PALB2
Domain Architecture	No domain graphic available
Description	Partner and localizer of BRCA2.

TGON2_HUMAN
NC score	0.006144 (rank : 95)	θ value	1.81305 (rank : 66)
Query Neighborhood Hits	112	Target Neighborhood Hits	1037	Shared Neighborhood Hits	15
SwissProt Accessions	O43493, O15282, O43492, O43499, O43500, O43501, Q92760	Gene names	TGOLN2, TGN46, TGN51
Domain Architecture
Description	Trans-Golgi network integral membrane protein 2 precursor (Trans-Golgi network protein TGN51) (TGN46) (TGN48) (TGN38 homolog).

STK31_MOUSE
NC score	0.005762 (rank : 96)	θ value	4.03905 (rank : 81)
Query Neighborhood Hits	112	Target Neighborhood Hits	474	Shared Neighborhood Hits	3
SwissProt Accessions	Q99MW1	Gene names	Stk31
Domain Architecture
Description	Serine/threonine-protein kinase 31 (EC 2.7.11.1).

TCF20_MOUSE
NC score	0.005493 (rank : 97)	θ value	6.88961 (rank : 102)
Query Neighborhood Hits	112	Target Neighborhood Hits	396	Shared Neighborhood Hits	5
SwissProt Accessions	Q9EPQ8, Q60792	Gene names	Tcf20, Spbp
Domain Architecture	No domain graphic available
Description	Transcription factor 20 (Stromelysin 1 PDGF-responsive element-binding protein) (SPRE-binding protein) (Nuclear factor SPBP).

MUC1_MOUSE
NC score	0.005365 (rank : 98)	θ value	8.99809 (rank : 107)
Query Neighborhood Hits	112	Target Neighborhood Hits	388	Shared Neighborhood Hits	6
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

ZN638_HUMAN
NC score	0.005294 (rank : 99)	θ value	8.99809 (rank : 112)
Query Neighborhood Hits	112	Target Neighborhood Hits	343	Shared Neighborhood Hits	8
SwissProt Accessions	Q14966, Q53R34, Q5XJ05, Q68DP3, Q6P2H2, Q7Z3T7, Q8NF92, Q8TCA1, Q9H2G1, Q9NP37	Gene names	ZNF638, NP220, ZFML
Domain Architecture	No domain graphic available
Description	Zinc finger protein 638 (Nuclear protein 220) (Zinc-finger matrin-like protein) (Cutaneous T-cell lymphoma-associated antigen se33-1) (CTCL tumor antigen se33-1).

E41L2_MOUSE
NC score	0.004585 (rank : 100)	θ value	4.03905 (rank : 79)
Query Neighborhood Hits	112	Target Neighborhood Hits	459	Shared Neighborhood Hits	6
SwissProt Accessions	O70318	Gene names	Epb41l2, Epb4.1l2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

IF4G1_HUMAN
NC score	0.003572 (rank : 101)	θ value	8.99809 (rank : 106)
Query Neighborhood Hits	112	Target Neighborhood Hits	347	Shared Neighborhood Hits	5
SwissProt Accessions	Q04637, O43177, O95066, Q5HYG0, Q6ZN21, Q8N102	Gene names	EIF4G1, EIF4G, EIF4GI
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 1 (eIF-4-gamma 1) (eIF-4G1) (eIF-4G 1) (p220).

ELF1_MOUSE
NC score	0.003543 (rank : 102)	θ value	6.88961 (rank : 98)
Query Neighborhood Hits	112	Target Neighborhood Hits	139	Shared Neighborhood Hits	4
SwissProt Accessions	Q60775	Gene names	Elf1
Domain Architecture
Description	ETS-related transcription factor Elf-1 (E74-like factor 1).

TRPS1_HUMAN
NC score	0.003278 (rank : 103)	θ value	6.88961 (rank : 104)
Query Neighborhood Hits	112	Target Neighborhood Hits	539	Shared Neighborhood Hits	3
SwissProt Accessions	Q9UHF7, Q9NWE1, Q9UHH6	Gene names	TRPS1
Domain Architecture
Description	Zinc finger transcription factor Trps1 (Zinc finger protein GC79) (Tricho-rhino-phalangeal syndrome type I protein).

RASA2_HUMAN
NC score	0.002887 (rank : 104)	θ value	6.88961 (rank : 101)
Query Neighborhood Hits	112	Target Neighborhood Hits	157	Shared Neighborhood Hits	2
SwissProt Accessions	Q15283, O00695, Q15284, Q92594, Q99577, Q9UEQ2	Gene names	RASA2, GAP1M, RASGAP
Domain Architecture
Description	Ras GTPase-activating protein 2 (GAP1m).

NACAM_MOUSE
NC score	0.002242 (rank : 105)	θ value	5.27518 (rank : 89)
Query Neighborhood Hits	112	Target Neighborhood Hits	1866	Shared Neighborhood Hits	16
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

TIF1G_MOUSE
NC score	0.002015 (rank : 106)	θ value	5.27518 (rank : 93)
Query Neighborhood Hits	112	Target Neighborhood Hits	498	Shared Neighborhood Hits	5
SwissProt Accessions	Q99PP7, Q6SI71, Q6ZPX5	Gene names	Trim33, Kiaa1113
Domain Architecture	No domain graphic available
Description	Transcription intermediary factor 1-gamma (TIF1-gamma) (Tripartite motif-containing protein 33).

SYNE1_HUMAN
NC score	0.001186 (rank : 107)	θ value	4.03905 (rank : 82)
Query Neighborhood Hits	112	Target Neighborhood Hits	1484	Shared Neighborhood Hits	14
SwissProt Accessions	Q8NF91, O94890, Q5JV19, Q5JV22, Q8N9P7, Q8TCP1, Q8WWW6, Q8WWW7, Q8WXF6, Q96N17, Q9C0A7, Q9H525, Q9H526, Q9NS36, Q9NU50, Q9UJ06, Q9UJ07, Q9ULF8	Gene names	SYNE1, KIAA0796, KIAA1262, KIAA1756, MYNE1
Domain Architecture
Description	Nesprin-1 (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1) (Myocyte nuclear envelope protein 1) (Myne-1) (Enaptin).

TLR3_HUMAN
NC score	0.000073 (rank : 108)	θ value	5.27518 (rank : 94)
Query Neighborhood Hits	112	Target Neighborhood Hits	323	Shared Neighborhood Hits	2
SwissProt Accessions	O15455	Gene names	TLR3
Domain Architecture
Description	Toll-like receptor 3 precursor (CD283 antigen).

ZBTB9_MOUSE
NC score	-0.000383 (rank : 109)	θ value	1.81305 (rank : 67)
Query Neighborhood Hits	112	Target Neighborhood Hits	780	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CDC7, Q3U3B2, Q9CYQ0	Gene names	Zbtb9
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 9.

CTTB2_HUMAN
NC score	-0.001019 (rank : 110)	θ value	6.88961 (rank : 97)
Query Neighborhood Hits	112	Target Neighborhood Hits	1061	Shared Neighborhood Hits	9
SwissProt Accessions	Q8WZ74, O43389, Q7LG11, Q9C0A5	Gene names	CTTNBP2, C7orf8, CORTBP2, KIAA1758
Domain Architecture	No domain graphic available
Description	Cortactin-binding protein 2 (CortBP2).

RIPK3_MOUSE
NC score	-0.003188 (rank : 111)	θ value	2.36792 (rank : 73)
Query Neighborhood Hits	112	Target Neighborhood Hits	867	Shared Neighborhood Hits	2
SwissProt Accessions	Q9QZL0	Gene names	Ripk3, Rip3
Domain Architecture
Description	Receptor-interacting serine/threonine-protein kinase 3 (EC 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) (mRIP3).

ZN445_MOUSE
NC score	-0.004654 (rank : 112)	θ value	4.03905 (rank : 84)
Query Neighborhood Hits	112	Target Neighborhood Hits	760	Shared Neighborhood Hits	4
SwissProt Accessions	Q8R2V3, Q8K216	Gene names	Znf445, Zfp445
Domain Architecture
Description	Zinc finger protein 445.