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Network neighborhood for query Sequence : DIP2A_HUMAN

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DIP2A_HUMAN
SwissProt Accessions	Q14689, Q8IVA3, Q8N4S2, Q8TD89, Q96ML9	Gene names	DIP2A, C21orf106, DIP2, KIAA0184
Domain Architecture
Description	Disco-interacting protein 2 homolog A.
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

DIP2A_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	48	Target Neighborhood Hits	48	Shared Neighborhood Hits	48
SwissProt Accessions	Q14689, Q8IVA3, Q8N4S2, Q8TD89, Q96ML9	Gene names	DIP2A, C21orf106, DIP2, KIAA0184
Domain Architecture
Description	Disco-interacting protein 2 homolog A.

DIP2A_MOUSE
θ value	0 (rank : 2)	NC score	0.996276 (rank : 2)
Query Neighborhood Hits	48	Target Neighborhood Hits	32	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BWT5, Q8CHI0	Gene names	Dip2a, Dip2, Kiaa0184
Domain Architecture
Description	Disco-interacting protein 2 homolog A.

DIP2C_HUMAN
θ value	0 (rank : 3)	NC score	0.991840 (rank : 3)
Query Neighborhood Hits	48	Target Neighborhood Hits	32	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y2E4	Gene names	DIP2C, KIAA0934
Domain Architecture
Description	Disco-interacting protein 2 homolog C.

RP1L1_HUMAN
θ value	0.00869519 (rank : 4)	NC score	0.047757 (rank : 9)
Query Neighborhood Hits	48	Target Neighborhood Hits	1072	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

GNPTA_MOUSE
θ value	0.0736092 (rank : 5)	NC score	0.121957 (rank : 4)
Query Neighborhood Hits	48	Target Neighborhood Hits	47	Shared Neighborhood Hits	5
SwissProt Accessions	Q69ZN6, Q3U3K6, Q3US34	Gene names	Gnptab, Gnpta, Kiaa1208
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphotransferase subunits alpha/beta precursor (EC 2.7.8.17) (GlcNAc-1-phosphotransferase alpha/beta subunits) (UDP- N-acetylglucosamine-1-phosphotransferase alpha/beta subunits) (Stealth protein GNPTAB) [Contains: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta].

GNPTA_HUMAN
θ value	0.21417 (rank : 6)	NC score	0.098749 (rank : 5)
Query Neighborhood Hits	48	Target Neighborhood Hits	43	Shared Neighborhood Hits	5
SwissProt Accessions	Q3T906, Q3ZQK2, Q6IPW5, Q86TQ2, Q96N13, Q9ULL2	Gene names	GNPTAB, GNPTA, KIAA1208
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphotransferase subunits alpha/beta precursor (EC 2.7.8.17) (GlcNAc-1-phosphotransferase alpha/beta subunits) (UDP- N-acetylglucosamine-1-phosphotransferase alpha/beta subunits) (Stealth protein GNPTAB) [Contains: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta].

MAST1_MOUSE
θ value	0.21417 (rank : 7)	NC score	0.008068 (rank : 40)
Query Neighborhood Hits	48	Target Neighborhood Hits	1123	Shared Neighborhood Hits	9
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

APC7_HUMAN
θ value	0.365318 (rank : 8)	NC score	0.069186 (rank : 6)
Query Neighborhood Hits	48	Target Neighborhood Hits	57	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UJX3, Q96AC4, Q96GF4, Q9BU24, Q9NT16	Gene names	ANAPC7, APC7
Domain Architecture
Description	Anaphase-promoting complex subunit 7 (APC7) (Cyclosome subunit 7).

SP100_HUMAN
θ value	0.365318 (rank : 9)	NC score	0.025441 (rank : 18)
Query Neighborhood Hits	48	Target Neighborhood Hits	117	Shared Neighborhood Hits	2
SwissProt Accessions	P23497, O75450, Q13343, Q96F70, Q96T24, Q96T95, Q9NP33, Q9UE32	Gene names	SP100
Domain Architecture
Description	Nuclear autoantigen Sp-100 (Speckled 100 kDa) (Nuclear dot-associated Sp100 protein) (Lysp100b).

ABL1_HUMAN
θ value	0.813845 (rank : 10)	NC score	0.005171 (rank : 45)
Query Neighborhood Hits	48	Target Neighborhood Hits	1220	Shared Neighborhood Hits	9
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

APC7_MOUSE
θ value	0.813845 (rank : 11)	NC score	0.061514 (rank : 7)
Query Neighborhood Hits	48	Target Neighborhood Hits	56	Shared Neighborhood Hits	4
SwissProt Accessions	Q9WVM3, Q3UBM7, Q8BSR2, Q91W13	Gene names	Anapc7, Apc7
Domain Architecture
Description	Anaphase-promoting complex subunit 7 (APC7) (Cyclosome subunit 7) (Prediabetic NOD sera-reactive autoantigen).

CS021_HUMAN
θ value	0.813845 (rank : 12)	NC score	0.034624 (rank : 13)
Query Neighborhood Hits	48	Target Neighborhood Hits	98	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IVT2	Gene names	C19orf21
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf21.

RPKL1_HUMAN
θ value	0.813845 (rank : 13)	NC score	0.027814 (rank : 17)
Query Neighborhood Hits	48	Target Neighborhood Hits	708	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y6S9, Q69YT9, Q6ZMQ6, Q96NR9, Q9BSU9	Gene names	RPS6KL1
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase-like 1 (EC 2.7.11.1).

K0240_MOUSE
θ value	1.06291 (rank : 14)	NC score	0.039425 (rank : 11)
Query Neighborhood Hits	48	Target Neighborhood Hits	211	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CHH5	Gene names	Kiaa0240
Domain Architecture	No domain graphic available
Description	Protein KIAA0240.

TARA_MOUSE
θ value	1.06291 (rank : 15)	NC score	0.016856 (rank : 32)
Query Neighborhood Hits	48	Target Neighborhood Hits	1133	Shared Neighborhood Hits	8
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

CAF1B_MOUSE
θ value	1.38821 (rank : 16)	NC score	0.012817 (rank : 34)
Query Neighborhood Hits	48	Target Neighborhood Hits	385	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D0N7	Gene names	Chaf1b
Domain Architecture
Description	Chromatin assembly factor 1 subunit B (CAF-1 subunit B) (Chromatin assembly factor I p60 subunit) (CAF-I 60 kDa subunit) (CAF-Ip60).

GP139_MOUSE
θ value	1.38821 (rank : 17)	NC score	0.023570 (rank : 20)
Query Neighborhood Hits	48	Target Neighborhood Hits	637	Shared Neighborhood Hits	4
SwissProt Accessions	Q80UC8	Gene names	Gpr139, Gprg1, Pgr3
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 139 (G(q)-coupled orphan receptor GPRg1) (G-protein-coupled receptor PGR3).

ATX1_MOUSE
θ value	1.81305 (rank : 18)	NC score	0.034216 (rank : 14)
Query Neighborhood Hits	48	Target Neighborhood Hits	264	Shared Neighborhood Hits	4
SwissProt Accessions	P54254	Gene names	Atxn1, Sca1
Domain Architecture
Description	Ataxin-1 (Spinocerebellar ataxia type 1 protein homolog).

GP139_HUMAN
θ value	1.81305 (rank : 19)	NC score	0.022171 (rank : 24)
Query Neighborhood Hits	48	Target Neighborhood Hits	640	Shared Neighborhood Hits	4
SwissProt Accessions	Q6DWJ6, Q86SP2, Q8TDU8	Gene names	GPR139, GPRG1, PGR3
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 139 (G(q)-coupled orphan receptor GPRg1) (G-protein-coupled receptor PGR3).

RPKL1_MOUSE
θ value	1.81305 (rank : 20)	NC score	0.023388 (rank : 22)
Query Neighborhood Hits	48	Target Neighborhood Hits	704	Shared Neighborhood Hits	10
SwissProt Accessions	Q8R2S1, Q8R1D4	Gene names	Rps6kl1
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase-like 1 (EC 2.7.11.1).

S27A6_HUMAN
θ value	1.81305 (rank : 21)	NC score	0.037387 (rank : 12)
Query Neighborhood Hits	48	Target Neighborhood Hits	26	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y2P4, Q6IAM5, Q7Z6E6, Q86YF6	Gene names	SLC27A6, ACSVL2, FACVL2, FATP1
Domain Architecture	No domain graphic available
Description	Long-chain fatty acid transport protein 6 (Fatty acid transport protein 6) (FATP-6) (Very long-chain acyl-CoA synthetase homolog 1) (VLCSH1) (hVLCS-H1) (Fatty-acid-coenzyme A ligase, very long-chain 2) (Solute carrier family 27 member 6).

SFRS8_HUMAN
θ value	1.81305 (rank : 22)	NC score	0.052953 (rank : 8)
Query Neighborhood Hits	48	Target Neighborhood Hits	166	Shared Neighborhood Hits	9
SwissProt Accessions	Q12872	Gene names	SFRS8, SWAP
Domain Architecture
Description	Splicing factor, arginine/serine-rich 8 (Suppressor of white apricot protein homolog).

SPEG_MOUSE
θ value	1.81305 (rank : 23)	NC score	0.007651 (rank : 41)
Query Neighborhood Hits	48	Target Neighborhood Hits	1959	Shared Neighborhood Hits	18
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

DNMT1_MOUSE
θ value	2.36792 (rank : 24)	NC score	0.023421 (rank : 21)
Query Neighborhood Hits	48	Target Neighborhood Hits	137	Shared Neighborhood Hits	3
SwissProt Accessions	P13864, P97413, Q80ZU3, Q9CSC6, Q9QXX6	Gene names	Dnmt1, Dnmt, Met1, Uim
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase MmuI) (DNA MTase MmuI) (MCMT) (M.MmuI) (Met-1).

S27A3_MOUSE
θ value	2.36792 (rank : 25)	NC score	0.040028 (rank : 10)
Query Neighborhood Hits	48	Target Neighborhood Hits	32	Shared Neighborhood Hits	7
SwissProt Accessions	O88561, Q6PAU1, Q8BK70	Gene names	Slc27a3, Acsvl3, Fatp3
Domain Architecture	No domain graphic available
Description	Long-chain fatty acid transport protein 3 (EC 6.2.1.-) (Fatty acid transport protein 3) (FATP-3) (Solute carrier family 27 member 3).

PHF20_HUMAN
θ value	3.0926 (rank : 26)	NC score	0.017807 (rank : 29)
Query Neighborhood Hits	48	Target Neighborhood Hits	394	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BVI0, Q5JWY9, Q9BWV4, Q9BXA3, Q9BZW3, Q9H421, Q9H4J6, Q9NZ22	Gene names	PHF20, C20orf104, GLEA2, HCA58, NZF, TZP
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58) (Glioma-expressed antigen 2) (Transcription factor TZP) (Novel zinc finger protein).

SF3A1_HUMAN
θ value	3.0926 (rank : 27)	NC score	0.029575 (rank : 15)
Query Neighborhood Hits	48	Target Neighborhood Hits	199	Shared Neighborhood Hits	7
SwissProt Accessions	Q15459	Gene names	SF3A1, SAP114
Domain Architecture
Description	Splicing factor 3 subunit 1 (Spliceosome-associated protein 114) (SAP 114) (SF3a120).

SF3A1_MOUSE
θ value	3.0926 (rank : 28)	NC score	0.029453 (rank : 16)
Query Neighborhood Hits	48	Target Neighborhood Hits	198	Shared Neighborhood Hits	6
SwissProt Accessions	Q8K4Z5, Q8C0M7, Q8C128, Q8C175, Q921T3	Gene names	Sf3a1
Domain Architecture	No domain graphic available
Description	Splicing factor 3 subunit 1 (SF3a120).

SPRR3_MOUSE
θ value	3.0926 (rank : 29)	NC score	0.023128 (rank : 23)
Query Neighborhood Hits	48	Target Neighborhood Hits	106	Shared Neighborhood Hits	6
SwissProt Accessions	O09116	Gene names	Sprr3
Domain Architecture
Description	Small proline-rich protein 3 (Cornifin beta).

K2027_MOUSE
θ value	4.03905 (rank : 30)	NC score	0.018349 (rank : 27)
Query Neighborhood Hits	48	Target Neighborhood Hits	106	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BWS5, Q69Z30	Gene names	Kiaa2027
Domain Architecture	No domain graphic available
Description	Protein KIAA2027.

LRIG1_MOUSE
θ value	4.03905 (rank : 31)	NC score	0.006591 (rank : 43)
Query Neighborhood Hits	48	Target Neighborhood Hits	627	Shared Neighborhood Hits	4
SwissProt Accessions	P70193	Gene names	Lrig1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 1 precursor (LIG-1).

ABL1_MOUSE
θ value	5.27518 (rank : 32)	NC score	0.003669 (rank : 47)
Query Neighborhood Hits	48	Target Neighborhood Hits	1178	Shared Neighborhood Hits	8
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

FIGN_MOUSE
θ value	5.27518 (rank : 33)	NC score	0.013366 (rank : 33)
Query Neighborhood Hits	48	Target Neighborhood Hits	165	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ERZ6, Q3TPB0, Q3UP57, Q6PCM0	Gene names	Fign
Domain Architecture	No domain graphic available
Description	Fidgetin.

PKDRE_MOUSE
θ value	5.27518 (rank : 34)	NC score	0.018487 (rank : 26)
Query Neighborhood Hits	48	Target Neighborhood Hits	76	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z0T6	Gene names	Pkdrej
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

PPHLN_HUMAN
θ value	5.27518 (rank : 35)	NC score	0.017395 (rank : 30)
Query Neighborhood Hits	48	Target Neighborhood Hits	75	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NEY8, Q86YT2, Q8IXN3, Q8TB09, Q96NB9, Q9NXL4, Q9P0P6, Q9P0R9	Gene names	PPHLN1
Domain Architecture	No domain graphic available
Description	Periphilin-1 (Gastric cancer antigen Ga50).

S27A2_MOUSE
θ value	5.27518 (rank : 36)	NC score	0.024429 (rank : 19)
Query Neighborhood Hits	48	Target Neighborhood Hits	27	Shared Neighborhood Hits	6
SwissProt Accessions	O35488, O70550, O88560	Gene names	Slc27a2, Acsvl1, Facvl1, Fatp2, Vlacs, Vlcs
Domain Architecture
Description	Very-long-chain acyl-CoA synthetase (EC 6.2.1.-) (VLCS) (Very-long- chain-fatty-acid-CoA ligase) (VLACS) (THCA-CoA ligase) (Fatty-acid- coenzyme A ligase, very long-chain 1) (Long-chain-fatty-acid--CoA ligase) (EC 6.2.1.3) (Fatty acid transport protein 2) (FATP-2) (Solute carrier family 27 member 2).

BTBDC_HUMAN
θ value	6.88961 (rank : 37)	NC score	0.018050 (rank : 28)
Query Neighborhood Hits	48	Target Neighborhood Hits	248	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IY92, Q96JP1	Gene names	BTBD12, KIAA1784
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 12.

GP112_HUMAN
θ value	6.88961 (rank : 38)	NC score	0.008115 (rank : 39)
Query Neighborhood Hits	48	Target Neighborhood Hits	441	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

PKN3_MOUSE
θ value	6.88961 (rank : 39)	NC score	0.004087 (rank : 46)
Query Neighborhood Hits	48	Target Neighborhood Hits	1009	Shared Neighborhood Hits	8
SwissProt Accessions	Q8K045	Gene names	Pkn3, Pknbeta
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein kinase PKN- beta) (Protein-kinase C-related kinase 3).

RASF3_HUMAN
θ value	6.88961 (rank : 40)	NC score	0.011268 (rank : 37)
Query Neighborhood Hits	48	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	Q86WH2, Q86WH1	Gene names	RASSF3
Domain Architecture	No domain graphic available
Description	Ras association domain-containing protein 3.

ADA12_HUMAN
θ value	8.99809 (rank : 41)	NC score	0.002545 (rank : 48)
Query Neighborhood Hits	48	Target Neighborhood Hits	224	Shared Neighborhood Hits	2
SwissProt Accessions	O43184, O60470	Gene names	ADAM12, MLTN
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).

CIR_MOUSE
θ value	8.99809 (rank : 42)	NC score	0.010301 (rank : 38)
Query Neighborhood Hits	48	Target Neighborhood Hits	255	Shared Neighborhood Hits	3
SwissProt Accessions	Q9DA19, Q3V2N9, Q4KL44, Q52KL9, Q5FW66	Gene names	Cir
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor.

DNMT1_HUMAN
θ value	8.99809 (rank : 43)	NC score	0.017268 (rank : 31)
Query Neighborhood Hits	48	Target Neighborhood Hits	401	Shared Neighborhood Hits	7
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

EYA4_HUMAN
θ value	8.99809 (rank : 44)	NC score	0.012227 (rank : 36)
Query Neighborhood Hits	48	Target Neighborhood Hits	95	Shared Neighborhood Hits	4
SwissProt Accessions	O95677, O95464, O95679, Q8IW39, Q9NTR7	Gene names	EYA4
Domain Architecture
Description	Eyes absent homolog 4 (EC 3.1.3.48).

EYA4_MOUSE
θ value	8.99809 (rank : 45)	NC score	0.012601 (rank : 35)
Query Neighborhood Hits	48	Target Neighborhood Hits	74	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z191	Gene names	Eya4
Domain Architecture
Description	Eyes absent homolog 4 (EC 3.1.3.48).

HBS1L_MOUSE
θ value	8.99809 (rank : 46)	NC score	0.006489 (rank : 44)
Query Neighborhood Hits	48	Target Neighborhood Hits	65	Shared Neighborhood Hits	2
SwissProt Accessions	Q69ZS7, Q91Z32, Q9CVT2, Q9CZ95, Q9WTY5	Gene names	Hbs1l, Hbs1, Kiaa1038
Domain Architecture	No domain graphic available
Description	HBS1-like protein.

S27A2_HUMAN
θ value	8.99809 (rank : 47)	NC score	0.018912 (rank : 25)
Query Neighborhood Hits	48	Target Neighborhood Hits	30	Shared Neighborhood Hits	5
SwissProt Accessions	O14975	Gene names	SLC27A2, ACSVL1, FACVL1, FATP2, VLACS
Domain Architecture
Description	Very-long-chain acyl-CoA synthetase (EC 6.2.1.-) (VLCS) (Very-long- chain-fatty-acid-CoA ligase) (VLACS) (THCA-CoA ligase) (Fatty-acid- coenzyme A ligase, very long-chain 1) (Long-chain-fatty-acid--CoA ligase) (EC 6.2.1.3) (Fatty acid transport protein 2) (FATP-2) (Solute carrier family 27 member 2).

TRAF7_MOUSE
θ value	8.99809 (rank : 48)	NC score	0.007650 (rank : 42)
Query Neighborhood Hits	48	Target Neighborhood Hits	470	Shared Neighborhood Hits	4
SwissProt Accessions	Q922B6, Q99JV3	Gene names	Traf7
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7).

Hits sorted by NC score

DIP2A_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	48	Target Neighborhood Hits	48	Shared Neighborhood Hits	48
SwissProt Accessions	Q14689, Q8IVA3, Q8N4S2, Q8TD89, Q96ML9	Gene names	DIP2A, C21orf106, DIP2, KIAA0184
Domain Architecture
Description	Disco-interacting protein 2 homolog A.

DIP2A_MOUSE
NC score	0.996276 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	48	Target Neighborhood Hits	32	Shared Neighborhood Hits	24
SwissProt Accessions	Q8BWT5, Q8CHI0	Gene names	Dip2a, Dip2, Kiaa0184
Domain Architecture
Description	Disco-interacting protein 2 homolog A.

DIP2C_HUMAN
NC score	0.991840 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	48	Target Neighborhood Hits	32	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y2E4	Gene names	DIP2C, KIAA0934
Domain Architecture
Description	Disco-interacting protein 2 homolog C.

GNPTA_MOUSE
NC score	0.121957 (rank : 4)	θ value	0.0736092 (rank : 5)
Query Neighborhood Hits	48	Target Neighborhood Hits	47	Shared Neighborhood Hits	5
SwissProt Accessions	Q69ZN6, Q3U3K6, Q3US34	Gene names	Gnptab, Gnpta, Kiaa1208
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphotransferase subunits alpha/beta precursor (EC 2.7.8.17) (GlcNAc-1-phosphotransferase alpha/beta subunits) (UDP- N-acetylglucosamine-1-phosphotransferase alpha/beta subunits) (Stealth protein GNPTAB) [Contains: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta].

GNPTA_HUMAN
NC score	0.098749 (rank : 5)	θ value	0.21417 (rank : 6)
Query Neighborhood Hits	48	Target Neighborhood Hits	43	Shared Neighborhood Hits	5
SwissProt Accessions	Q3T906, Q3ZQK2, Q6IPW5, Q86TQ2, Q96N13, Q9ULL2	Gene names	GNPTAB, GNPTA, KIAA1208
Domain Architecture	No domain graphic available
Description	N-acetylglucosamine-1-phosphotransferase subunits alpha/beta precursor (EC 2.7.8.17) (GlcNAc-1-phosphotransferase alpha/beta subunits) (UDP- N-acetylglucosamine-1-phosphotransferase alpha/beta subunits) (Stealth protein GNPTAB) [Contains: N-acetylglucosamine-1-phosphotransferase subunit alpha; N-acetylglucosamine-1-phosphotransferase subunit beta].

APC7_HUMAN
NC score	0.069186 (rank : 6)	θ value	0.365318 (rank : 8)
Query Neighborhood Hits	48	Target Neighborhood Hits	57	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UJX3, Q96AC4, Q96GF4, Q9BU24, Q9NT16	Gene names	ANAPC7, APC7
Domain Architecture
Description	Anaphase-promoting complex subunit 7 (APC7) (Cyclosome subunit 7).

APC7_MOUSE
NC score	0.061514 (rank : 7)	θ value	0.813845 (rank : 11)
Query Neighborhood Hits	48	Target Neighborhood Hits	56	Shared Neighborhood Hits	4
SwissProt Accessions	Q9WVM3, Q3UBM7, Q8BSR2, Q91W13	Gene names	Anapc7, Apc7
Domain Architecture
Description	Anaphase-promoting complex subunit 7 (APC7) (Cyclosome subunit 7) (Prediabetic NOD sera-reactive autoantigen).

SFRS8_HUMAN
NC score	0.052953 (rank : 8)	θ value	1.81305 (rank : 22)
Query Neighborhood Hits	48	Target Neighborhood Hits	166	Shared Neighborhood Hits	9
SwissProt Accessions	Q12872	Gene names	SFRS8, SWAP
Domain Architecture
Description	Splicing factor, arginine/serine-rich 8 (Suppressor of white apricot protein homolog).

RP1L1_HUMAN
NC score	0.047757 (rank : 9)	θ value	0.00869519 (rank : 4)
Query Neighborhood Hits	48	Target Neighborhood Hits	1072	Shared Neighborhood Hits	8
SwissProt Accessions	Q8IWN7, Q86SQ1, Q8IWN8, Q8IWN9, Q8IWP0, Q8IWP1, Q8IWP2	Gene names	RP1L1
Domain Architecture
Description	Retinitis pigmentosa 1-like 1 protein.

S27A3_MOUSE
NC score	0.040028 (rank : 10)	θ value	2.36792 (rank : 25)
Query Neighborhood Hits	48	Target Neighborhood Hits	32	Shared Neighborhood Hits	7
SwissProt Accessions	O88561, Q6PAU1, Q8BK70	Gene names	Slc27a3, Acsvl3, Fatp3
Domain Architecture	No domain graphic available
Description	Long-chain fatty acid transport protein 3 (EC 6.2.1.-) (Fatty acid transport protein 3) (FATP-3) (Solute carrier family 27 member 3).

K0240_MOUSE
NC score	0.039425 (rank : 11)	θ value	1.06291 (rank : 14)
Query Neighborhood Hits	48	Target Neighborhood Hits	211	Shared Neighborhood Hits	4
SwissProt Accessions	Q8CHH5	Gene names	Kiaa0240
Domain Architecture	No domain graphic available
Description	Protein KIAA0240.

S27A6_HUMAN
NC score	0.037387 (rank : 12)	θ value	1.81305 (rank : 21)
Query Neighborhood Hits	48	Target Neighborhood Hits	26	Shared Neighborhood Hits	7
SwissProt Accessions	Q9Y2P4, Q6IAM5, Q7Z6E6, Q86YF6	Gene names	SLC27A6, ACSVL2, FACVL2, FATP1
Domain Architecture	No domain graphic available
Description	Long-chain fatty acid transport protein 6 (Fatty acid transport protein 6) (FATP-6) (Very long-chain acyl-CoA synthetase homolog 1) (VLCSH1) (hVLCS-H1) (Fatty-acid-coenzyme A ligase, very long-chain 2) (Solute carrier family 27 member 6).

CS021_HUMAN
NC score	0.034624 (rank : 13)	θ value	0.813845 (rank : 12)
Query Neighborhood Hits	48	Target Neighborhood Hits	98	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IVT2	Gene names	C19orf21
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C19orf21.

ATX1_MOUSE
NC score	0.034216 (rank : 14)	θ value	1.81305 (rank : 18)
Query Neighborhood Hits	48	Target Neighborhood Hits	264	Shared Neighborhood Hits	4
SwissProt Accessions	P54254	Gene names	Atxn1, Sca1
Domain Architecture
Description	Ataxin-1 (Spinocerebellar ataxia type 1 protein homolog).

SF3A1_HUMAN
NC score	0.029575 (rank : 15)	θ value	3.0926 (rank : 27)
Query Neighborhood Hits	48	Target Neighborhood Hits	199	Shared Neighborhood Hits	7
SwissProt Accessions	Q15459	Gene names	SF3A1, SAP114
Domain Architecture
Description	Splicing factor 3 subunit 1 (Spliceosome-associated protein 114) (SAP 114) (SF3a120).

SF3A1_MOUSE
NC score	0.029453 (rank : 16)	θ value	3.0926 (rank : 28)
Query Neighborhood Hits	48	Target Neighborhood Hits	198	Shared Neighborhood Hits	6
SwissProt Accessions	Q8K4Z5, Q8C0M7, Q8C128, Q8C175, Q921T3	Gene names	Sf3a1
Domain Architecture	No domain graphic available
Description	Splicing factor 3 subunit 1 (SF3a120).

RPKL1_HUMAN
NC score	0.027814 (rank : 17)	θ value	0.813845 (rank : 13)
Query Neighborhood Hits	48	Target Neighborhood Hits	708	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Y6S9, Q69YT9, Q6ZMQ6, Q96NR9, Q9BSU9	Gene names	RPS6KL1
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase-like 1 (EC 2.7.11.1).

SP100_HUMAN
NC score	0.025441 (rank : 18)	θ value	0.365318 (rank : 9)
Query Neighborhood Hits	48	Target Neighborhood Hits	117	Shared Neighborhood Hits	2
SwissProt Accessions	P23497, O75450, Q13343, Q96F70, Q96T24, Q96T95, Q9NP33, Q9UE32	Gene names	SP100
Domain Architecture
Description	Nuclear autoantigen Sp-100 (Speckled 100 kDa) (Nuclear dot-associated Sp100 protein) (Lysp100b).

S27A2_MOUSE
NC score	0.024429 (rank : 19)	θ value	5.27518 (rank : 36)
Query Neighborhood Hits	48	Target Neighborhood Hits	27	Shared Neighborhood Hits	6
SwissProt Accessions	O35488, O70550, O88560	Gene names	Slc27a2, Acsvl1, Facvl1, Fatp2, Vlacs, Vlcs
Domain Architecture
Description	Very-long-chain acyl-CoA synthetase (EC 6.2.1.-) (VLCS) (Very-long- chain-fatty-acid-CoA ligase) (VLACS) (THCA-CoA ligase) (Fatty-acid- coenzyme A ligase, very long-chain 1) (Long-chain-fatty-acid--CoA ligase) (EC 6.2.1.3) (Fatty acid transport protein 2) (FATP-2) (Solute carrier family 27 member 2).

GP139_MOUSE
NC score	0.023570 (rank : 20)	θ value	1.38821 (rank : 17)
Query Neighborhood Hits	48	Target Neighborhood Hits	637	Shared Neighborhood Hits	4
SwissProt Accessions	Q80UC8	Gene names	Gpr139, Gprg1, Pgr3
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 139 (G(q)-coupled orphan receptor GPRg1) (G-protein-coupled receptor PGR3).

DNMT1_MOUSE
NC score	0.023421 (rank : 21)	θ value	2.36792 (rank : 24)
Query Neighborhood Hits	48	Target Neighborhood Hits	137	Shared Neighborhood Hits	3
SwissProt Accessions	P13864, P97413, Q80ZU3, Q9CSC6, Q9QXX6	Gene names	Dnmt1, Dnmt, Met1, Uim
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase MmuI) (DNA MTase MmuI) (MCMT) (M.MmuI) (Met-1).

RPKL1_MOUSE
NC score	0.023388 (rank : 22)	θ value	1.81305 (rank : 20)
Query Neighborhood Hits	48	Target Neighborhood Hits	704	Shared Neighborhood Hits	10
SwissProt Accessions	Q8R2S1, Q8R1D4	Gene names	Rps6kl1
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase-like 1 (EC 2.7.11.1).

SPRR3_MOUSE
NC score	0.023128 (rank : 23)	θ value	3.0926 (rank : 29)
Query Neighborhood Hits	48	Target Neighborhood Hits	106	Shared Neighborhood Hits	6
SwissProt Accessions	O09116	Gene names	Sprr3
Domain Architecture
Description	Small proline-rich protein 3 (Cornifin beta).

GP139_HUMAN
NC score	0.022171 (rank : 24)	θ value	1.81305 (rank : 19)
Query Neighborhood Hits	48	Target Neighborhood Hits	640	Shared Neighborhood Hits	4
SwissProt Accessions	Q6DWJ6, Q86SP2, Q8TDU8	Gene names	GPR139, GPRG1, PGR3
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 139 (G(q)-coupled orphan receptor GPRg1) (G-protein-coupled receptor PGR3).

S27A2_HUMAN
NC score	0.018912 (rank : 25)	θ value	8.99809 (rank : 47)
Query Neighborhood Hits	48	Target Neighborhood Hits	30	Shared Neighborhood Hits	5
SwissProt Accessions	O14975	Gene names	SLC27A2, ACSVL1, FACVL1, FATP2, VLACS
Domain Architecture
Description	Very-long-chain acyl-CoA synthetase (EC 6.2.1.-) (VLCS) (Very-long- chain-fatty-acid-CoA ligase) (VLACS) (THCA-CoA ligase) (Fatty-acid- coenzyme A ligase, very long-chain 1) (Long-chain-fatty-acid--CoA ligase) (EC 6.2.1.3) (Fatty acid transport protein 2) (FATP-2) (Solute carrier family 27 member 2).

PKDRE_MOUSE
NC score	0.018487 (rank : 26)	θ value	5.27518 (rank : 34)
Query Neighborhood Hits	48	Target Neighborhood Hits	76	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z0T6	Gene names	Pkdrej
Domain Architecture
Description	Polycystic kidney disease and receptor for egg jelly-related protein precursor (PKD and REJ homolog).

K2027_MOUSE
NC score	0.018349 (rank : 27)	θ value	4.03905 (rank : 30)
Query Neighborhood Hits	48	Target Neighborhood Hits	106	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BWS5, Q69Z30	Gene names	Kiaa2027
Domain Architecture	No domain graphic available
Description	Protein KIAA2027.

BTBDC_HUMAN
NC score	0.018050 (rank : 28)	θ value	6.88961 (rank : 37)
Query Neighborhood Hits	48	Target Neighborhood Hits	248	Shared Neighborhood Hits	6
SwissProt Accessions	Q8IY92, Q96JP1	Gene names	BTBD12, KIAA1784
Domain Architecture	No domain graphic available
Description	BTB/POZ domain-containing protein 12.

PHF20_HUMAN
NC score	0.017807 (rank : 29)	θ value	3.0926 (rank : 26)
Query Neighborhood Hits	48	Target Neighborhood Hits	394	Shared Neighborhood Hits	7
SwissProt Accessions	Q9BVI0, Q5JWY9, Q9BWV4, Q9BXA3, Q9BZW3, Q9H421, Q9H4J6, Q9NZ22	Gene names	PHF20, C20orf104, GLEA2, HCA58, NZF, TZP
Domain Architecture
Description	PHD finger protein 20 (Hepatocellular carcinoma-associated antigen 58) (Glioma-expressed antigen 2) (Transcription factor TZP) (Novel zinc finger protein).

PPHLN_HUMAN
NC score	0.017395 (rank : 30)	θ value	5.27518 (rank : 35)
Query Neighborhood Hits	48	Target Neighborhood Hits	75	Shared Neighborhood Hits	2
SwissProt Accessions	Q8NEY8, Q86YT2, Q8IXN3, Q8TB09, Q96NB9, Q9NXL4, Q9P0P6, Q9P0R9	Gene names	PPHLN1
Domain Architecture	No domain graphic available
Description	Periphilin-1 (Gastric cancer antigen Ga50).

DNMT1_HUMAN
NC score	0.017268 (rank : 31)	θ value	8.99809 (rank : 43)
Query Neighborhood Hits	48	Target Neighborhood Hits	401	Shared Neighborhood Hits	7
SwissProt Accessions	P26358, Q9UHG5, Q9ULA2, Q9UMZ6	Gene names	DNMT1, AIM, DNMT
Domain Architecture
Description	DNA (cytosine-5)-methyltransferase 1 (EC 2.1.1.37) (Dnmt1) (DNA methyltransferase HsaI) (DNA MTase HsaI) (MCMT) (M.HsaI).

TARA_MOUSE
NC score	0.016856 (rank : 32)	θ value	1.06291 (rank : 15)
Query Neighborhood Hits	48	Target Neighborhood Hits	1133	Shared Neighborhood Hits	8
SwissProt Accessions	Q99KW3, Q2PZW9, Q2Q402, Q2Q403, Q2Q404, Q6ZPK4, Q8C6T3, Q8CG90	Gene names	Triobp, Kiaa1662, Tara
Domain Architecture	No domain graphic available
Description	TRIO and F-actin-binding protein (Protein Tara) (Trio-associated repeat on actin).

FIGN_MOUSE
NC score	0.013366 (rank : 33)	θ value	5.27518 (rank : 33)
Query Neighborhood Hits	48	Target Neighborhood Hits	165	Shared Neighborhood Hits	3
SwissProt Accessions	Q9ERZ6, Q3TPB0, Q3UP57, Q6PCM0	Gene names	Fign
Domain Architecture	No domain graphic available
Description	Fidgetin.

CAF1B_MOUSE
NC score	0.012817 (rank : 34)	θ value	1.38821 (rank : 16)
Query Neighborhood Hits	48	Target Neighborhood Hits	385	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D0N7	Gene names	Chaf1b
Domain Architecture
Description	Chromatin assembly factor 1 subunit B (CAF-1 subunit B) (Chromatin assembly factor I p60 subunit) (CAF-I 60 kDa subunit) (CAF-Ip60).

EYA4_MOUSE
NC score	0.012601 (rank : 35)	θ value	8.99809 (rank : 45)
Query Neighborhood Hits	48	Target Neighborhood Hits	74	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z191	Gene names	Eya4
Domain Architecture
Description	Eyes absent homolog 4 (EC 3.1.3.48).

EYA4_HUMAN
NC score	0.012227 (rank : 36)	θ value	8.99809 (rank : 44)
Query Neighborhood Hits	48	Target Neighborhood Hits	95	Shared Neighborhood Hits	4
SwissProt Accessions	O95677, O95464, O95679, Q8IW39, Q9NTR7	Gene names	EYA4
Domain Architecture
Description	Eyes absent homolog 4 (EC 3.1.3.48).

RASF3_HUMAN
NC score	0.011268 (rank : 37)	θ value	6.88961 (rank : 40)
Query Neighborhood Hits	48	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	Q86WH2, Q86WH1	Gene names	RASSF3
Domain Architecture	No domain graphic available
Description	Ras association domain-containing protein 3.

CIR_MOUSE
NC score	0.010301 (rank : 38)	θ value	8.99809 (rank : 42)
Query Neighborhood Hits	48	Target Neighborhood Hits	255	Shared Neighborhood Hits	3
SwissProt Accessions	Q9DA19, Q3V2N9, Q4KL44, Q52KL9, Q5FW66	Gene names	Cir
Domain Architecture	No domain graphic available
Description	CBF1-interacting corepressor.

GP112_HUMAN
NC score	0.008115 (rank : 39)	θ value	6.88961 (rank : 38)
Query Neighborhood Hits	48	Target Neighborhood Hits	441	Shared Neighborhood Hits	4
SwissProt Accessions	Q8IZF6, Q86SM6	Gene names	GPR112
Domain Architecture	No domain graphic available
Description	Probable G-protein coupled receptor 112.

MAST1_MOUSE
NC score	0.008068 (rank : 40)	θ value	0.21417 (rank : 7)
Query Neighborhood Hits	48	Target Neighborhood Hits	1123	Shared Neighborhood Hits	9
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

SPEG_MOUSE
NC score	0.007651 (rank : 41)	θ value	1.81305 (rank : 23)
Query Neighborhood Hits	48	Target Neighborhood Hits	1959	Shared Neighborhood Hits	18
SwissProt Accessions	Q62407, Q3TPH8, Q6P5V1, Q80TF7, Q80ZN0, Q8BZF4, Q9EQJ5	Gene names	Speg, Apeg1, Kiaa1297
Domain Architecture
Description	Striated muscle-specific serine/threonine protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

TRAF7_MOUSE
NC score	0.007650 (rank : 42)	θ value	8.99809 (rank : 48)
Query Neighborhood Hits	48	Target Neighborhood Hits	470	Shared Neighborhood Hits	4
SwissProt Accessions	Q922B6, Q99JV3	Gene names	Traf7
Domain Architecture	No domain graphic available
Description	E3 ubiquitin protein ligase TRAF7 (EC 6.3.2.-) (TNF receptor- associated factor 7).

LRIG1_MOUSE
NC score	0.006591 (rank : 43)	θ value	4.03905 (rank : 31)
Query Neighborhood Hits	48	Target Neighborhood Hits	627	Shared Neighborhood Hits	4
SwissProt Accessions	P70193	Gene names	Lrig1
Domain Architecture	No domain graphic available
Description	Leucine-rich repeats and immunoglobulin-like domains protein 1 precursor (LIG-1).

HBS1L_MOUSE
NC score	0.006489 (rank : 44)	θ value	8.99809 (rank : 46)
Query Neighborhood Hits	48	Target Neighborhood Hits	65	Shared Neighborhood Hits	2
SwissProt Accessions	Q69ZS7, Q91Z32, Q9CVT2, Q9CZ95, Q9WTY5	Gene names	Hbs1l, Hbs1, Kiaa1038
Domain Architecture	No domain graphic available
Description	HBS1-like protein.

ABL1_HUMAN
NC score	0.005171 (rank : 45)	θ value	0.813845 (rank : 10)
Query Neighborhood Hits	48	Target Neighborhood Hits	1220	Shared Neighborhood Hits	9
SwissProt Accessions	P00519, Q13869, Q13870, Q16133, Q45F09	Gene names	ABL1, ABL, JTK7
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

PKN3_MOUSE
NC score	0.004087 (rank : 46)	θ value	6.88961 (rank : 39)
Query Neighborhood Hits	48	Target Neighborhood Hits	1009	Shared Neighborhood Hits	8
SwissProt Accessions	Q8K045	Gene names	Pkn3, Pknbeta
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein kinase PKN- beta) (Protein-kinase C-related kinase 3).

ABL1_MOUSE
NC score	0.003669 (rank : 47)	θ value	5.27518 (rank : 32)
Query Neighborhood Hits	48	Target Neighborhood Hits	1178	Shared Neighborhood Hits	8
SwissProt Accessions	P00520, P97896, Q61252, Q61253, Q61254, Q61255, Q61256, Q61257, Q61258, Q61259, Q61260, Q61261, Q6PCM5, Q8C1X4	Gene names	Abl1, Abl
Domain Architecture
Description	Proto-oncogene tyrosine-protein kinase ABL1 (EC 2.7.10.2) (p150) (c- ABL) (Abelson murine leukemia viral oncogene homolog 1).

ADA12_HUMAN
NC score	0.002545 (rank : 48)	θ value	8.99809 (rank : 41)
Query Neighborhood Hits	48	Target Neighborhood Hits	224	Shared Neighborhood Hits	2
SwissProt Accessions	O43184, O60470	Gene names	ADAM12, MLTN
Domain Architecture
Description	ADAM 12 precursor (EC 3.4.24.-) (A disintegrin and metalloproteinase domain 12) (Meltrin alpha).