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Network neighborhood for query Sequence : MEPD_HUMAN

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MEPD_HUMAN
SwissProt Accessions	P52888, Q9UCB3	Gene names	THOP1
Domain Architecture
Description	Thimet oligopeptidase (EC 3.4.24.15) (Endopeptidase 24.15) (MP78).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

MEPD_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	39	Target Neighborhood Hits	39	Shared Neighborhood Hits	39
SwissProt Accessions	P52888, Q9UCB3	Gene names	THOP1
Domain Architecture
Description	Thimet oligopeptidase (EC 3.4.24.15) (Endopeptidase 24.15) (MP78).

NEUL_HUMAN
θ value	0 (rank : 2)	NC score	0.976795 (rank : 2)
Query Neighborhood Hits	39	Target Neighborhood Hits	19	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BYT8, Q9ULJ4	Gene names	NLN, KIAA1226
Domain Architecture
Description	Neurolysin, mitochondrial precursor (EC 3.4.24.16) (Neurotensin endopeptidase) (Mitochondrial oligopeptidase M) (Microsomal endopeptidase) (MEP).

PMIP_HUMAN
θ value	1.61718e-49 (rank : 3)	NC score	0.811705 (rank : 3)
Query Neighborhood Hits	39	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q99797	Gene names	MIPEP, MIP
Domain Architecture
Description	Mitochondrial intermediate peptidase, mitochondrial precursor (EC 3.4.24.59) (MIP).

GOGA4_HUMAN
θ value	0.00869519 (rank : 4)	NC score	0.048154 (rank : 11)
Query Neighborhood Hits	39	Target Neighborhood Hits	2034	Shared Neighborhood Hits	30
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

EVPL_MOUSE
θ value	0.0252991 (rank : 5)	NC score	0.053777 (rank : 5)
Query Neighborhood Hits	39	Target Neighborhood Hits	952	Shared Neighborhood Hits	26
SwissProt Accessions	Q9D952	Gene names	Evpl
Domain Architecture
Description	Envoplakin (p210) (210 kDa cornified envelope precursor protein).

MYO5C_HUMAN
θ value	0.0252991 (rank : 6)	NC score	0.039101 (rank : 18)
Query Neighborhood Hits	39	Target Neighborhood Hits	1206	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

RBCC1_MOUSE
θ value	0.0961366 (rank : 7)	NC score	0.051947 (rank : 7)
Query Neighborhood Hits	39	Target Neighborhood Hits	1048	Shared Neighborhood Hits	26
SwissProt Accessions	Q9ESK9, Q3TXX2, Q61384, Q8BRY9, Q9JK14	Gene names	Rb1cc1, Cc1, Kiaa0203
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1 (Coiled-coil-forming protein 1) (LaXp180 protein).

CCD46_MOUSE
θ value	0.125558 (rank : 8)	NC score	0.048899 (rank : 10)
Query Neighborhood Hits	39	Target Neighborhood Hits	1405	Shared Neighborhood Hits	30
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

EVI1_HUMAN
θ value	0.163984 (rank : 9)	NC score	0.006963 (rank : 39)
Query Neighborhood Hits	39	Target Neighborhood Hits	924	Shared Neighborhood Hits	3
SwissProt Accessions	Q03112, Q16122, Q99917	Gene names	EVI1
Domain Architecture
Description	Ecotropic virus integration 1 site protein.

SYCP1_HUMAN
θ value	0.365318 (rank : 10)	NC score	0.046971 (rank : 13)
Query Neighborhood Hits	39	Target Neighborhood Hits	1313	Shared Neighborhood Hits	27
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

AKAP9_HUMAN
θ value	1.06291 (rank : 11)	NC score	0.047503 (rank : 12)
Query Neighborhood Hits	39	Target Neighborhood Hits	1710	Shared Neighborhood Hits	29
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

SPT6H_HUMAN
θ value	1.06291 (rank : 12)	NC score	0.053361 (rank : 6)
Query Neighborhood Hits	39	Target Neighborhood Hits	104	Shared Neighborhood Hits	3
SwissProt Accessions	Q7KZ85, Q15737, Q6GMQ4, Q7KYW9, Q7LDK4, Q8N526, Q92775, Q96AH3, Q9BTH9, Q9BTI2	Gene names	SUPT6H, KIAA0162, SPT6H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT6 (hSPT6) (Tat-cotransactivator 2 protein) (Tat-CT2 protein).

SPT6H_MOUSE
θ value	1.06291 (rank : 13)	NC score	0.055101 (rank : 4)
Query Neighborhood Hits	39	Target Neighborhood Hits	104	Shared Neighborhood Hits	4
SwissProt Accessions	Q62383, Q5SYM0, Q6GQS3, Q6ZQI0, Q8BQY6	Gene names	Supt6h, Kiaa0162
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT6.

CCD96_MOUSE
θ value	1.38821 (rank : 14)	NC score	0.048908 (rank : 9)
Query Neighborhood Hits	39	Target Neighborhood Hits	704	Shared Neighborhood Hits	23
SwissProt Accessions	Q9CR92	Gene names	Ccdc96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

NUCB1_HUMAN
θ value	1.38821 (rank : 15)	NC score	0.044409 (rank : 16)
Query Neighborhood Hits	39	Target Neighborhood Hits	359	Shared Neighborhood Hits	18
SwissProt Accessions	Q02818, Q15838, Q7Z4J7, Q9BUR1	Gene names	NUCB1, NUC
Domain Architecture	No domain graphic available
Description	Nucleobindin-1 precursor (CALNUC).

ROCK1_MOUSE
θ value	1.38821 (rank : 16)	NC score	0.021870 (rank : 28)
Query Neighborhood Hits	39	Target Neighborhood Hits	2126	Shared Neighborhood Hits	28
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

SYNE2_HUMAN
θ value	1.38821 (rank : 17)	NC score	0.036632 (rank : 20)
Query Neighborhood Hits	39	Target Neighborhood Hits	1323	Shared Neighborhood Hits	25
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

MYH11_HUMAN
θ value	1.81305 (rank : 18)	NC score	0.032282 (rank : 22)
Query Neighborhood Hits	39	Target Neighborhood Hits	1806	Shared Neighborhood Hits	30
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

CGAT2_MOUSE
θ value	2.36792 (rank : 19)	NC score	0.021597 (rank : 29)
Query Neighborhood Hits	39	Target Neighborhood Hits	61	Shared Neighborhood Hits	5
SwissProt Accessions	Q8C1F4, Q6PAP6, Q8R5A2, Q9D2M1	Gene names	Galnact2, Chgn2
Domain Architecture	No domain graphic available
Description	Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 2 (EC 2.4.1.174) (GalNAcT-2) (beta4GalNAcT-2).

RAI14_MOUSE
θ value	2.36792 (rank : 20)	NC score	0.028837 (rank : 26)
Query Neighborhood Hits	39	Target Neighborhood Hits	1505	Shared Neighborhood Hits	27
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

ROCK1_HUMAN
θ value	2.36792 (rank : 21)	NC score	0.020519 (rank : 30)
Query Neighborhood Hits	39	Target Neighborhood Hits	2000	Shared Neighborhood Hits	28
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).

SP100_HUMAN
θ value	2.36792 (rank : 22)	NC score	0.019090 (rank : 31)
Query Neighborhood Hits	39	Target Neighborhood Hits	117	Shared Neighborhood Hits	2
SwissProt Accessions	P23497, O75450, Q13343, Q96F70, Q96T24, Q96T95, Q9NP33, Q9UE32	Gene names	SP100
Domain Architecture
Description	Nuclear autoantigen Sp-100 (Speckled 100 kDa) (Nuclear dot-associated Sp100 protein) (Lysp100b).

SYCP1_MOUSE
θ value	2.36792 (rank : 23)	NC score	0.050458 (rank : 8)
Query Neighborhood Hits	39	Target Neighborhood Hits	1456	Shared Neighborhood Hits	29
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

CALD1_HUMAN
θ value	3.0926 (rank : 24)	NC score	0.040184 (rank : 17)
Query Neighborhood Hits	39	Target Neighborhood Hits	959	Shared Neighborhood Hits	26
SwissProt Accessions	Q05682, Q13978, Q13979, Q14741, Q14742	Gene names	CALD1, CAD, CDM
Domain Architecture
Description	Caldesmon (CDM).

CCD46_HUMAN
θ value	3.0926 (rank : 25)	NC score	0.044433 (rank : 15)
Query Neighborhood Hits	39	Target Neighborhood Hits	1430	Shared Neighborhood Hits	27
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

CCD96_HUMAN
θ value	4.03905 (rank : 26)	NC score	0.046013 (rank : 14)
Query Neighborhood Hits	39	Target Neighborhood Hits	595	Shared Neighborhood Hits	22
SwissProt Accessions	Q2M329, Q8N2I7	Gene names	CCDC96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

M4K4_MOUSE
θ value	4.03905 (rank : 27)	NC score	0.010658 (rank : 34)
Query Neighborhood Hits	39	Target Neighborhood Hits	1560	Shared Neighborhood Hits	26
SwissProt Accessions	P97820	Gene names	Map4k4, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

AK1E1_MOUSE
θ value	5.27518 (rank : 28)	NC score	0.009546 (rank : 36)
Query Neighborhood Hits	39	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	Q9DCT1, O09125	Gene names	Akr1e1
Domain Architecture
Description	Aldo-keto reductase family 1 member E1 (EC 1.1.1.-).

MYH11_MOUSE
θ value	5.27518 (rank : 29)	NC score	0.031043 (rank : 24)
Query Neighborhood Hits	39	Target Neighborhood Hits	1777	Shared Neighborhood Hits	29
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYH6_HUMAN
θ value	5.27518 (rank : 30)	NC score	0.029547 (rank : 25)
Query Neighborhood Hits	39	Target Neighborhood Hits	1426	Shared Neighborhood Hits	26
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

NUCB1_MOUSE
θ value	5.27518 (rank : 31)	NC score	0.037381 (rank : 19)
Query Neighborhood Hits	39	Target Neighborhood Hits	414	Shared Neighborhood Hits	21
SwissProt Accessions	Q02819, Q3TU42, Q9CWA1, Q9D8J4, Q9DBL3	Gene names	Nucb1, Nuc, Nucb
Domain Architecture	No domain graphic available
Description	Nucleobindin-1 precursor (CALNUC).

AMPH_HUMAN
θ value	6.88961 (rank : 32)	NC score	0.015511 (rank : 33)
Query Neighborhood Hits	39	Target Neighborhood Hits	455	Shared Neighborhood Hits	10
SwissProt Accessions	P49418, O43538, Q75MJ8, Q75MK5, Q75MM3, Q8N4G0	Gene names	AMPH, AMPH1
Domain Architecture
Description	Amphiphysin.

CENPF_HUMAN
θ value	6.88961 (rank : 33)	NC score	0.034790 (rank : 21)
Query Neighborhood Hits	39	Target Neighborhood Hits	1932	Shared Neighborhood Hits	28
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

M4K4_HUMAN
θ value	6.88961 (rank : 34)	NC score	0.010587 (rank : 35)
Query Neighborhood Hits	39	Target Neighborhood Hits	1589	Shared Neighborhood Hits	26
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

MRCKA_HUMAN
θ value	6.88961 (rank : 35)	NC score	0.017045 (rank : 32)
Query Neighborhood Hits	39	Target Neighborhood Hits	1999	Shared Neighborhood Hits	27
SwissProt Accessions	Q5VT25, Q59GZ1, Q5H9N9, Q5T797, Q5VT26, Q5VT27, Q86XX2, Q86XX3, Q99646	Gene names	CDC42BPA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42- binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) (DMPK-like alpha).

XL3A_MOUSE
θ value	6.88961 (rank : 36)	NC score	0.026734 (rank : 27)
Query Neighborhood Hits	39	Target Neighborhood Hits	140	Shared Neighborhood Hits	13
SwissProt Accessions	Q60595	Gene names	Xlr3a
Domain Architecture
Description	X-linked lymphocyte-regulated protein 3A.

EP400_MOUSE
θ value	8.99809 (rank : 37)	NC score	0.008599 (rank : 37)
Query Neighborhood Hits	39	Target Neighborhood Hits	592	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

GPX5_HUMAN
θ value	8.99809 (rank : 38)	NC score	0.008542 (rank : 38)
Query Neighborhood Hits	39	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	O75715	Gene names	GPX5
Domain Architecture
Description	Epididymal secretory glutathione peroxidase precursor (EC 1.11.1.9) (Epididymis-specific glutathione peroxidase-like protein) (EGLP).

OPTN_HUMAN
θ value	8.99809 (rank : 39)	NC score	0.031934 (rank : 23)
Query Neighborhood Hits	39	Target Neighborhood Hits	827	Shared Neighborhood Hits	23
SwissProt Accessions	Q96CV9, Q5T672, Q5T673, Q5T674, Q5T675, Q7LDL9, Q8N562, Q9UET9, Q9UEV4, Q9Y218	Gene names	OPTN, FIP2, GLC1E, NRP
Domain Architecture	No domain graphic available
Description	Optineurin (Optic neuropathy-inducing protein) (E3-14.7K-interacting protein) (FIP-2) (Huntingtin-interacting protein HYPL) (NEMO-related protein) (Transcription factor IIIA-interacting protein) (TFIIIA- IntP).

Hits sorted by NC score

MEPD_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	39	Target Neighborhood Hits	39	Shared Neighborhood Hits	39
SwissProt Accessions	P52888, Q9UCB3	Gene names	THOP1
Domain Architecture
Description	Thimet oligopeptidase (EC 3.4.24.15) (Endopeptidase 24.15) (MP78).

NEUL_HUMAN
NC score	0.976795 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	39	Target Neighborhood Hits	19	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BYT8, Q9ULJ4	Gene names	NLN, KIAA1226
Domain Architecture
Description	Neurolysin, mitochondrial precursor (EC 3.4.24.16) (Neurotensin endopeptidase) (Mitochondrial oligopeptidase M) (Microsomal endopeptidase) (MEP).

PMIP_HUMAN
NC score	0.811705 (rank : 3)	θ value	1.61718e-49 (rank : 3)
Query Neighborhood Hits	39	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q99797	Gene names	MIPEP, MIP
Domain Architecture
Description	Mitochondrial intermediate peptidase, mitochondrial precursor (EC 3.4.24.59) (MIP).

SPT6H_MOUSE
NC score	0.055101 (rank : 4)	θ value	1.06291 (rank : 13)
Query Neighborhood Hits	39	Target Neighborhood Hits	104	Shared Neighborhood Hits	4
SwissProt Accessions	Q62383, Q5SYM0, Q6GQS3, Q6ZQI0, Q8BQY6	Gene names	Supt6h, Kiaa0162
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT6.

EVPL_MOUSE
NC score	0.053777 (rank : 5)	θ value	0.0252991 (rank : 5)
Query Neighborhood Hits	39	Target Neighborhood Hits	952	Shared Neighborhood Hits	26
SwissProt Accessions	Q9D952	Gene names	Evpl
Domain Architecture
Description	Envoplakin (p210) (210 kDa cornified envelope precursor protein).

SPT6H_HUMAN
NC score	0.053361 (rank : 6)	θ value	1.06291 (rank : 12)
Query Neighborhood Hits	39	Target Neighborhood Hits	104	Shared Neighborhood Hits	3
SwissProt Accessions	Q7KZ85, Q15737, Q6GMQ4, Q7KYW9, Q7LDK4, Q8N526, Q92775, Q96AH3, Q9BTH9, Q9BTI2	Gene names	SUPT6H, KIAA0162, SPT6H
Domain Architecture	No domain graphic available
Description	Transcription elongation factor SPT6 (hSPT6) (Tat-cotransactivator 2 protein) (Tat-CT2 protein).

RBCC1_MOUSE
NC score	0.051947 (rank : 7)	θ value	0.0961366 (rank : 7)
Query Neighborhood Hits	39	Target Neighborhood Hits	1048	Shared Neighborhood Hits	26
SwissProt Accessions	Q9ESK9, Q3TXX2, Q61384, Q8BRY9, Q9JK14	Gene names	Rb1cc1, Cc1, Kiaa0203
Domain Architecture	No domain graphic available
Description	RB1-inducible coiled-coil protein 1 (Coiled-coil-forming protein 1) (LaXp180 protein).

SYCP1_MOUSE
NC score	0.050458 (rank : 8)	θ value	2.36792 (rank : 23)
Query Neighborhood Hits	39	Target Neighborhood Hits	1456	Shared Neighborhood Hits	29
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

CCD96_MOUSE
NC score	0.048908 (rank : 9)	θ value	1.38821 (rank : 14)
Query Neighborhood Hits	39	Target Neighborhood Hits	704	Shared Neighborhood Hits	23
SwissProt Accessions	Q9CR92	Gene names	Ccdc96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

CCD46_MOUSE
NC score	0.048899 (rank : 10)	θ value	0.125558 (rank : 8)
Query Neighborhood Hits	39	Target Neighborhood Hits	1405	Shared Neighborhood Hits	30
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

GOGA4_HUMAN
NC score	0.048154 (rank : 11)	θ value	0.00869519 (rank : 4)
Query Neighborhood Hits	39	Target Neighborhood Hits	2034	Shared Neighborhood Hits	30
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

AKAP9_HUMAN
NC score	0.047503 (rank : 12)	θ value	1.06291 (rank : 11)
Query Neighborhood Hits	39	Target Neighborhood Hits	1710	Shared Neighborhood Hits	29
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

SYCP1_HUMAN
NC score	0.046971 (rank : 13)	θ value	0.365318 (rank : 10)
Query Neighborhood Hits	39	Target Neighborhood Hits	1313	Shared Neighborhood Hits	27
SwissProt Accessions	Q15431, O14963	Gene names	SYCP1, SCP1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

CCD96_HUMAN
NC score	0.046013 (rank : 14)	θ value	4.03905 (rank : 26)
Query Neighborhood Hits	39	Target Neighborhood Hits	595	Shared Neighborhood Hits	22
SwissProt Accessions	Q2M329, Q8N2I7	Gene names	CCDC96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

CCD46_HUMAN
NC score	0.044433 (rank : 15)	θ value	3.0926 (rank : 25)
Query Neighborhood Hits	39	Target Neighborhood Hits	1430	Shared Neighborhood Hits	27
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

NUCB1_HUMAN
NC score	0.044409 (rank : 16)	θ value	1.38821 (rank : 15)
Query Neighborhood Hits	39	Target Neighborhood Hits	359	Shared Neighborhood Hits	18
SwissProt Accessions	Q02818, Q15838, Q7Z4J7, Q9BUR1	Gene names	NUCB1, NUC
Domain Architecture	No domain graphic available
Description	Nucleobindin-1 precursor (CALNUC).

CALD1_HUMAN
NC score	0.040184 (rank : 17)	θ value	3.0926 (rank : 24)
Query Neighborhood Hits	39	Target Neighborhood Hits	959	Shared Neighborhood Hits	26
SwissProt Accessions	Q05682, Q13978, Q13979, Q14741, Q14742	Gene names	CALD1, CAD, CDM
Domain Architecture
Description	Caldesmon (CDM).

MYO5C_HUMAN
NC score	0.039101 (rank : 18)	θ value	0.0252991 (rank : 6)
Query Neighborhood Hits	39	Target Neighborhood Hits	1206	Shared Neighborhood Hits	27
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

NUCB1_MOUSE
NC score	0.037381 (rank : 19)	θ value	5.27518 (rank : 31)
Query Neighborhood Hits	39	Target Neighborhood Hits	414	Shared Neighborhood Hits	21
SwissProt Accessions	Q02819, Q3TU42, Q9CWA1, Q9D8J4, Q9DBL3	Gene names	Nucb1, Nuc, Nucb
Domain Architecture	No domain graphic available
Description	Nucleobindin-1 precursor (CALNUC).

SYNE2_HUMAN
NC score	0.036632 (rank : 20)	θ value	1.38821 (rank : 17)
Query Neighborhood Hits	39	Target Neighborhood Hits	1323	Shared Neighborhood Hits	25
SwissProt Accessions	Q8WXH0, Q8N1S3, Q8NF49, Q8TER7, Q8WWW3, Q8WWW4, Q8WWW5, Q8WXH1, Q9NU50, Q9UFQ4, Q9Y2L4, Q9Y4R1	Gene names	SYNE2, KIAA1011, NUA
Domain Architecture
Description	Nesprin-2 (Nuclear envelope spectrin repeat protein 2) (Syne-2) (Synaptic nuclear envelope protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE).

CENPF_HUMAN
NC score	0.034790 (rank : 21)	θ value	6.88961 (rank : 33)
Query Neighborhood Hits	39	Target Neighborhood Hits	1932	Shared Neighborhood Hits	28
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

MYH11_HUMAN
NC score	0.032282 (rank : 22)	θ value	1.81305 (rank : 18)
Query Neighborhood Hits	39	Target Neighborhood Hits	1806	Shared Neighborhood Hits	30
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

OPTN_HUMAN
NC score	0.031934 (rank : 23)	θ value	8.99809 (rank : 39)
Query Neighborhood Hits	39	Target Neighborhood Hits	827	Shared Neighborhood Hits	23
SwissProt Accessions	Q96CV9, Q5T672, Q5T673, Q5T674, Q5T675, Q7LDL9, Q8N562, Q9UET9, Q9UEV4, Q9Y218	Gene names	OPTN, FIP2, GLC1E, NRP
Domain Architecture	No domain graphic available
Description	Optineurin (Optic neuropathy-inducing protein) (E3-14.7K-interacting protein) (FIP-2) (Huntingtin-interacting protein HYPL) (NEMO-related protein) (Transcription factor IIIA-interacting protein) (TFIIIA- IntP).

MYH11_MOUSE
NC score	0.031043 (rank : 24)	θ value	5.27518 (rank : 29)
Query Neighborhood Hits	39	Target Neighborhood Hits	1777	Shared Neighborhood Hits	29
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYH6_HUMAN
NC score	0.029547 (rank : 25)	θ value	5.27518 (rank : 30)
Query Neighborhood Hits	39	Target Neighborhood Hits	1426	Shared Neighborhood Hits	26
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

RAI14_MOUSE
NC score	0.028837 (rank : 26)	θ value	2.36792 (rank : 20)
Query Neighborhood Hits	39	Target Neighborhood Hits	1505	Shared Neighborhood Hits	27
SwissProt Accessions	Q9EP71, Q3URT3, Q6ZPT6	Gene names	Rai14, Kiaa1334, Norpeg
Domain Architecture	No domain graphic available
Description	Ankycorbin (Ankyrin repeat and coiled-coil structure-containing protein) (Retinoic acid-induced protein 14) (Novel retinal pigment epithelial cell protein) (p125).

XL3A_MOUSE
NC score	0.026734 (rank : 27)	θ value	6.88961 (rank : 36)
Query Neighborhood Hits	39	Target Neighborhood Hits	140	Shared Neighborhood Hits	13
SwissProt Accessions	Q60595	Gene names	Xlr3a
Domain Architecture
Description	X-linked lymphocyte-regulated protein 3A.

ROCK1_MOUSE
NC score	0.021870 (rank : 28)	θ value	1.38821 (rank : 16)
Query Neighborhood Hits	39	Target Neighborhood Hits	2126	Shared Neighborhood Hits	28
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

CGAT2_MOUSE
NC score	0.021597 (rank : 29)	θ value	2.36792 (rank : 19)
Query Neighborhood Hits	39	Target Neighborhood Hits	61	Shared Neighborhood Hits	5
SwissProt Accessions	Q8C1F4, Q6PAP6, Q8R5A2, Q9D2M1	Gene names	Galnact2, Chgn2
Domain Architecture	No domain graphic available
Description	Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 2 (EC 2.4.1.174) (GalNAcT-2) (beta4GalNAcT-2).

ROCK1_HUMAN
NC score	0.020519 (rank : 30)	θ value	2.36792 (rank : 21)
Query Neighborhood Hits	39	Target Neighborhood Hits	2000	Shared Neighborhood Hits	28
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).

SP100_HUMAN
NC score	0.019090 (rank : 31)	θ value	2.36792 (rank : 22)
Query Neighborhood Hits	39	Target Neighborhood Hits	117	Shared Neighborhood Hits	2
SwissProt Accessions	P23497, O75450, Q13343, Q96F70, Q96T24, Q96T95, Q9NP33, Q9UE32	Gene names	SP100
Domain Architecture
Description	Nuclear autoantigen Sp-100 (Speckled 100 kDa) (Nuclear dot-associated Sp100 protein) (Lysp100b).

MRCKA_HUMAN
NC score	0.017045 (rank : 32)	θ value	6.88961 (rank : 35)
Query Neighborhood Hits	39	Target Neighborhood Hits	1999	Shared Neighborhood Hits	27
SwissProt Accessions	Q5VT25, Q59GZ1, Q5H9N9, Q5T797, Q5VT26, Q5VT27, Q86XX2, Q86XX3, Q99646	Gene names	CDC42BPA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42- binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) (DMPK-like alpha).

AMPH_HUMAN
NC score	0.015511 (rank : 33)	θ value	6.88961 (rank : 32)
Query Neighborhood Hits	39	Target Neighborhood Hits	455	Shared Neighborhood Hits	10
SwissProt Accessions	P49418, O43538, Q75MJ8, Q75MK5, Q75MM3, Q8N4G0	Gene names	AMPH, AMPH1
Domain Architecture
Description	Amphiphysin.

M4K4_MOUSE
NC score	0.010658 (rank : 34)	θ value	4.03905 (rank : 27)
Query Neighborhood Hits	39	Target Neighborhood Hits	1560	Shared Neighborhood Hits	26
SwissProt Accessions	P97820	Gene names	Map4k4, Nik
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

M4K4_HUMAN
NC score	0.010587 (rank : 35)	θ value	6.88961 (rank : 34)
Query Neighborhood Hits	39	Target Neighborhood Hits	1589	Shared Neighborhood Hits	26
SwissProt Accessions	O95819, O75172, Q9NST7	Gene names	MAP4K4, HGK, KIAA0687, NIK
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase kinase 4 (EC 2.7.11.1) (MAPK/ERK kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4) (HPK/GCK-like kinase HGK) (Nck-interacting kinase).

AK1E1_MOUSE
NC score	0.009546 (rank : 36)	θ value	5.27518 (rank : 28)
Query Neighborhood Hits	39	Target Neighborhood Hits	26	Shared Neighborhood Hits	2
SwissProt Accessions	Q9DCT1, O09125	Gene names	Akr1e1
Domain Architecture
Description	Aldo-keto reductase family 1 member E1 (EC 1.1.1.-).

EP400_MOUSE
NC score	0.008599 (rank : 37)	θ value	8.99809 (rank : 37)
Query Neighborhood Hits	39	Target Neighborhood Hits	592	Shared Neighborhood Hits	10
SwissProt Accessions	Q8CHI8, Q80TC8, Q8BXI5, Q8BYW3, Q8C0P6, Q8CHI7, Q8VDF4, Q9DA54	Gene names	Ep400, Kiaa1498
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (mDomino).

GPX5_HUMAN
NC score	0.008542 (rank : 38)	θ value	8.99809 (rank : 38)
Query Neighborhood Hits	39	Target Neighborhood Hits	17	Shared Neighborhood Hits	2
SwissProt Accessions	O75715	Gene names	GPX5
Domain Architecture
Description	Epididymal secretory glutathione peroxidase precursor (EC 1.11.1.9) (Epididymis-specific glutathione peroxidase-like protein) (EGLP).

EVI1_HUMAN
NC score	0.006963 (rank : 39)	θ value	0.163984 (rank : 9)
Query Neighborhood Hits	39	Target Neighborhood Hits	924	Shared Neighborhood Hits	3
SwissProt Accessions	Q03112, Q16122, Q99917	Gene names	EVI1
Domain Architecture
Description	Ecotropic virus integration 1 site protein.