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Network neighborhood for query Sequence : SMAD2_MOUSE

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SMAD2_MOUSE
SwissProt Accessions	Q62432, Q9D8P6	Gene names	Smad2, Madh2, Madr2
Domain Architecture
Description	Mothers against decapentaplegic homolog 2 (SMAD 2) (Mothers against DPP homolog 2) (Mad-related protein 2) (mMad2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SMAD2_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 2)
Query Neighborhood Hits	25	Target Neighborhood Hits	25	Shared Neighborhood Hits	25
SwissProt Accessions	Q15796	Gene names	SMAD2, MADH2, MADR2
Domain Architecture
Description	Mothers against decapentaplegic homolog 2 (SMAD 2) (Mothers against DPP homolog 2) (Mad-related protein 2) (hMAD-2) (JV18-1) (hSMAD2).

SMAD2_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	25	Target Neighborhood Hits	25	Shared Neighborhood Hits	25
SwissProt Accessions	Q62432, Q9D8P6	Gene names	Smad2, Madh2, Madr2
Domain Architecture
Description	Mothers against decapentaplegic homolog 2 (SMAD 2) (Mothers against DPP homolog 2) (Mad-related protein 2) (mMad2).

SMAD3_HUMAN
θ value	0 (rank : 3)	NC score	0.997604 (rank : 3)
Query Neighborhood Hits	25	Target Neighborhood Hits	25	Shared Neighborhood Hits	18
SwissProt Accessions	P84022, O09064, O09144, O14510, O35273, Q92940, Q93002, Q9GKR4	Gene names	SMAD3, MADH3
Domain Architecture
Description	Mothers against decapentaplegic homolog 3 (SMAD 3) (Mothers against DPP homolog 3) (Mad3) (hMAD-3) (JV15-2) (hSMAD3).

SMAD3_MOUSE
θ value	0 (rank : 4)	NC score	0.997604 (rank : 4)
Query Neighborhood Hits	25	Target Neighborhood Hits	25	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BUN5, O09064, O09144, O14510, O35273, Q8BX84, Q92940, Q93002, Q9GKR4	Gene names	Smad3, Madh3
Domain Architecture
Description	Mothers against decapentaplegic homolog 3 (SMAD 3) (Mothers against DPP homolog 3) (Mad3) (mMad3).

SMAD9_MOUSE
θ value	1.62758e-142 (rank : 5)	NC score	0.986646 (rank : 5)
Query Neighborhood Hits	25	Target Neighborhood Hits	75	Shared Neighborhood Hits	16
SwissProt Accessions	Q9JIW5, Q8CFF9	Gene names	Smad9, Madh8, Madh9, Smad8
Domain Architecture
Description	Mothers against decapentaplegic homolog 9 (SMAD 9) (Mothers against DPP homolog 9) (Smad9) (Smad8).

SMAD9_HUMAN
θ value	1.42583e-138 (rank : 6)	NC score	0.984535 (rank : 6)
Query Neighborhood Hits	25	Target Neighborhood Hits	48	Shared Neighborhood Hits	16
SwissProt Accessions	O15198, O14989	Gene names	SMAD9, MADH6, MADH9
Domain Architecture
Description	Mothers against decapentaplegic homolog 9 (SMAD 9) (Mothers against DPP homolog 9) (Smad9) (Madh6).

SMAD5_MOUSE
θ value	1.4755e-135 (rank : 7)	NC score	0.981670 (rank : 8)
Query Neighborhood Hits	25	Target Neighborhood Hits	74	Shared Neighborhood Hits	16
SwissProt Accessions	P97454, P70341, Q810K0	Gene names	Smad5, Madh5, Msmad5
Domain Architecture
Description	Mothers against decapentaplegic homolog 5 (SMAD 5) (Mothers against DPP homolog 5) (Smad5) (mSmad5) (Dwarfin-C) (Dwf-C).

SMAD5_HUMAN
θ value	9.56396e-135 (rank : 8)	NC score	0.983119 (rank : 7)
Query Neighborhood Hits	25	Target Neighborhood Hits	57	Shared Neighborhood Hits	16
SwissProt Accessions	Q99717, O14688, Q15798, Q9UQA1	Gene names	SMAD5, MADH5
Domain Architecture
Description	Mothers against decapentaplegic homolog 5 (SMAD 5) (Mothers against DPP homolog 5) (Smad5) (hSmad5) (JV5-1).

SMAD1_HUMAN
θ value	1.16911e-132 (rank : 9)	NC score	0.981138 (rank : 10)
Query Neighborhood Hits	25	Target Neighborhood Hits	59	Shared Neighborhood Hits	16
SwissProt Accessions	Q15797, Q16636	Gene names	SMAD1, BSP1, MADH1, MADR1
Domain Architecture
Description	Mothers against decapentaplegic homolog 1 (SMAD 1) (Mothers against DPP homolog 1) (Mad-related protein 1) (Transforming growth factor- beta signaling protein 1) (BSP-1) (hSMAD1) (JV4-1).

SMAD1_MOUSE
θ value	8.37844e-131 (rank : 10)	NC score	0.981221 (rank : 9)
Query Neighborhood Hits	25	Target Neighborhood Hits	56	Shared Neighborhood Hits	16
SwissProt Accessions	P70340, P70442, Q9CYK6	Gene names	Smad1, Madh1, Madr1
Domain Architecture
Description	Mothers against decapentaplegic homolog 1 (SMAD 1) (Mothers against DPP homolog 1) (Mad-related protein 1) (Mothers-against-DPP-related 1) (mMad1) (Dwarfin-A) (Dwf-A).

SMAD4_HUMAN
θ value	1.2411e-41 (rank : 11)	NC score	0.909937 (rank : 11)
Query Neighborhood Hits	25	Target Neighborhood Hits	72	Shared Neighborhood Hits	16
SwissProt Accessions	Q13485	Gene names	SMAD4, DPC4, MADH4
Domain Architecture
Description	Mothers against decapentaplegic homolog 4 (SMAD 4) (Mothers against DPP homolog 4) (Deletion target in pancreatic carcinoma 4) (hSMAD4).

SMAD4_MOUSE
θ value	1.2411e-41 (rank : 12)	NC score	0.906762 (rank : 12)
Query Neighborhood Hits	25	Target Neighborhood Hits	101	Shared Neighborhood Hits	16
SwissProt Accessions	P97471, Q9CW56	Gene names	Smad4, Dpc4, Madh4
Domain Architecture
Description	Mothers against decapentaplegic homolog 4 (SMAD 4) (Mothers against DPP homolog 4) (Deletion target in pancreatic carcinoma 4 homolog) (Smad4).

SMAD6_MOUSE
θ value	7.06379e-29 (rank : 13)	NC score	0.812617 (rank : 13)
Query Neighborhood Hits	25	Target Neighborhood Hits	22	Shared Neighborhood Hits	16
SwissProt Accessions	O35182, Q9CW62	Gene names	Smad6, Madh6, Madh7, Msmad6
Domain Architecture
Description	Mothers against decapentaplegic homolog 6 (SMAD 6) (Mothers against DPP homolog 6) (Smad6) (Mad homolog 7).

SMAD6_HUMAN
θ value	1.2049e-28 (rank : 14)	NC score	0.810357 (rank : 14)
Query Neighborhood Hits	25	Target Neighborhood Hits	31	Shared Neighborhood Hits	16
SwissProt Accessions	O43541, O43654, Q15799, Q9UKZ3	Gene names	SMAD6, MADH6
Domain Architecture
Description	Mothers against decapentaplegic homolog 6 (SMAD 6) (Mothers against DPP homolog 6) (Smad6) (hSMAD6).

SMAD7_HUMAN
θ value	1.24688e-25 (rank : 15)	NC score	0.798995 (rank : 16)
Query Neighborhood Hits	25	Target Neighborhood Hits	20	Shared Neighborhood Hits	16
SwissProt Accessions	O15105, O14740, Q6DK23	Gene names	SMAD7, MADH7, MADH8
Domain Architecture
Description	Mothers against decapentaplegic homolog 7 (SMAD 7) (Mothers against DPP homolog 7) (Smad7) (hSMAD7).

SMAD7_MOUSE
θ value	1.24688e-25 (rank : 16)	NC score	0.799806 (rank : 15)
Query Neighborhood Hits	25	Target Neighborhood Hits	18	Shared Neighborhood Hits	16
SwissProt Accessions	O35253, O88709	Gene names	Smad7, Madh7
Domain Architecture
Description	Mothers against decapentaplegic homolog 7 (SMAD 7) (Mothers against DPP homolog 7) (Smad7) (Madh8).

NU214_HUMAN
θ value	0.62314 (rank : 17)	NC score	0.025027 (rank : 18)
Query Neighborhood Hits	25	Target Neighborhood Hits	657	Shared Neighborhood Hits	4
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

PTN21_MOUSE
θ value	0.813845 (rank : 18)	NC score	0.011371 (rank : 20)
Query Neighborhood Hits	25	Target Neighborhood Hits	155	Shared Neighborhood Hits	5
SwissProt Accessions	Q62136	Gene names	Ptpn21
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-RL10).

IKBE_HUMAN
θ value	2.36792 (rank : 19)	NC score	0.008242 (rank : 23)
Query Neighborhood Hits	25	Target Neighborhood Hits	288	Shared Neighborhood Hits	3
SwissProt Accessions	O00221	Gene names	NFKBIE, IKBE
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKBE).

RBNS5_HUMAN
θ value	2.36792 (rank : 20)	NC score	0.017136 (rank : 19)
Query Neighborhood Hits	25	Target Neighborhood Hits	242	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H1K0, Q3KP30, Q59EY8, Q8NAQ1	Gene names	ZFYVE20
Domain Architecture	No domain graphic available
Description	Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (Zinc finger FYVE domain-containing protein 20) (110 kDa protein).

ITAX_HUMAN
θ value	4.03905 (rank : 21)	NC score	0.010035 (rank : 22)
Query Neighborhood Hits	25	Target Neighborhood Hits	81	Shared Neighborhood Hits	5
SwissProt Accessions	P20702, Q8IVA6	Gene names	ITGAX, CD11C
Domain Architecture
Description	Integrin alpha-X precursor (Leukocyte adhesion glycoprotein p150,95 alpha chain) (Leukocyte adhesion receptor p150,95) (Leu M5) (CD11c antigen).

GAB1_HUMAN
θ value	5.27518 (rank : 22)	NC score	0.010237 (rank : 21)
Query Neighborhood Hits	25	Target Neighborhood Hits	279	Shared Neighborhood Hits	4
SwissProt Accessions	Q13480, Q4W5G2, Q6P1W2	Gene names	GAB1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

PKP4_MOUSE
θ value	6.88961 (rank : 23)	NC score	0.005954 (rank : 25)
Query Neighborhood Hits	25	Target Neighborhood Hits	129	Shared Neighborhood Hits	3
SwissProt Accessions	Q68FH0, Q640N0, Q68G56, Q8BK47, Q8BVH1, Q9CRE3	Gene names	Pkp4, Armrp
Domain Architecture	No domain graphic available
Description	Plakophilin-4 (Armadillo-related protein).

ZEP1_HUMAN
θ value	6.88961 (rank : 24)	NC score	0.000495 (rank : 26)
Query Neighborhood Hits	25	Target Neighborhood Hits	1036	Shared Neighborhood Hits	5
SwissProt Accessions	P15822, Q14122	Gene names	HIVEP1, ZNF40
Domain Architecture	No domain graphic available
Description	Zinc finger protein 40 (Human immunodeficiency virus type I enhancer- binding protein 1) (HIV-EP1) (Major histocompatibility complex-binding protein 1) (MBP-1) (Positive regulatory domain II-binding factor 1) (PRDII-BF1).

UB7I1_MOUSE
θ value	8.99809 (rank : 25)	NC score	0.007744 (rank : 24)
Query Neighborhood Hits	25	Target Neighborhood Hits	206	Shared Neighborhood Hits	3
SwissProt Accessions	P58283, Q3U493, Q3UE56, Q3UGM3, Q68FN0, Q6P1H8, Q6PWY5, Q8BN27, Q8C1U3	Gene names	Ubce7ip1, Triad3, Uip83, Zin
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (UbcM4-interacting protein 83) (Triad domain- containing protein 3).

CRSP2_HUMAN
θ value	θ > 10 (rank : 26)	NC score	0.063079 (rank : 17)
Query Neighborhood Hits	25	Target Neighborhood Hits	380	Shared Neighborhood Hits	5
SwissProt Accessions	O60244, Q9UNB3	Gene names	CRSP2, ARC150, DRIP150, EXLM1, TRAP170
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 2 (Cofactor required for Sp1 transcriptional activation subunit 2) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Activator-recruited cofactor 150 kDa component) (ARC150).

Hits sorted by NC score

SMAD2_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	25	Target Neighborhood Hits	25	Shared Neighborhood Hits	25
SwissProt Accessions	Q62432, Q9D8P6	Gene names	Smad2, Madh2, Madr2
Domain Architecture
Description	Mothers against decapentaplegic homolog 2 (SMAD 2) (Mothers against DPP homolog 2) (Mad-related protein 2) (mMad2).

SMAD2_HUMAN
NC score	0.999962 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	25	Target Neighborhood Hits	25	Shared Neighborhood Hits	25
SwissProt Accessions	Q15796	Gene names	SMAD2, MADH2, MADR2
Domain Architecture
Description	Mothers against decapentaplegic homolog 2 (SMAD 2) (Mothers against DPP homolog 2) (Mad-related protein 2) (hMAD-2) (JV18-1) (hSMAD2).

SMAD3_HUMAN
NC score	0.997604 (rank : 3)	θ value	0 (rank : 3)
Query Neighborhood Hits	25	Target Neighborhood Hits	25	Shared Neighborhood Hits	18
SwissProt Accessions	P84022, O09064, O09144, O14510, O35273, Q92940, Q93002, Q9GKR4	Gene names	SMAD3, MADH3
Domain Architecture
Description	Mothers against decapentaplegic homolog 3 (SMAD 3) (Mothers against DPP homolog 3) (Mad3) (hMAD-3) (JV15-2) (hSMAD3).

SMAD3_MOUSE
NC score	0.997604 (rank : 4)	θ value	0 (rank : 4)
Query Neighborhood Hits	25	Target Neighborhood Hits	25	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BUN5, O09064, O09144, O14510, O35273, Q8BX84, Q92940, Q93002, Q9GKR4	Gene names	Smad3, Madh3
Domain Architecture
Description	Mothers against decapentaplegic homolog 3 (SMAD 3) (Mothers against DPP homolog 3) (Mad3) (mMad3).

SMAD9_MOUSE
NC score	0.986646 (rank : 5)	θ value	1.62758e-142 (rank : 5)
Query Neighborhood Hits	25	Target Neighborhood Hits	75	Shared Neighborhood Hits	16
SwissProt Accessions	Q9JIW5, Q8CFF9	Gene names	Smad9, Madh8, Madh9, Smad8
Domain Architecture
Description	Mothers against decapentaplegic homolog 9 (SMAD 9) (Mothers against DPP homolog 9) (Smad9) (Smad8).

SMAD9_HUMAN
NC score	0.984535 (rank : 6)	θ value	1.42583e-138 (rank : 6)
Query Neighborhood Hits	25	Target Neighborhood Hits	48	Shared Neighborhood Hits	16
SwissProt Accessions	O15198, O14989	Gene names	SMAD9, MADH6, MADH9
Domain Architecture
Description	Mothers against decapentaplegic homolog 9 (SMAD 9) (Mothers against DPP homolog 9) (Smad9) (Madh6).

SMAD5_HUMAN
NC score	0.983119 (rank : 7)	θ value	9.56396e-135 (rank : 8)
Query Neighborhood Hits	25	Target Neighborhood Hits	57	Shared Neighborhood Hits	16
SwissProt Accessions	Q99717, O14688, Q15798, Q9UQA1	Gene names	SMAD5, MADH5
Domain Architecture
Description	Mothers against decapentaplegic homolog 5 (SMAD 5) (Mothers against DPP homolog 5) (Smad5) (hSmad5) (JV5-1).

SMAD5_MOUSE
NC score	0.981670 (rank : 8)	θ value	1.4755e-135 (rank : 7)
Query Neighborhood Hits	25	Target Neighborhood Hits	74	Shared Neighborhood Hits	16
SwissProt Accessions	P97454, P70341, Q810K0	Gene names	Smad5, Madh5, Msmad5
Domain Architecture
Description	Mothers against decapentaplegic homolog 5 (SMAD 5) (Mothers against DPP homolog 5) (Smad5) (mSmad5) (Dwarfin-C) (Dwf-C).

SMAD1_MOUSE
NC score	0.981221 (rank : 9)	θ value	8.37844e-131 (rank : 10)
Query Neighborhood Hits	25	Target Neighborhood Hits	56	Shared Neighborhood Hits	16
SwissProt Accessions	P70340, P70442, Q9CYK6	Gene names	Smad1, Madh1, Madr1
Domain Architecture
Description	Mothers against decapentaplegic homolog 1 (SMAD 1) (Mothers against DPP homolog 1) (Mad-related protein 1) (Mothers-against-DPP-related 1) (mMad1) (Dwarfin-A) (Dwf-A).

SMAD1_HUMAN
NC score	0.981138 (rank : 10)	θ value	1.16911e-132 (rank : 9)
Query Neighborhood Hits	25	Target Neighborhood Hits	59	Shared Neighborhood Hits	16
SwissProt Accessions	Q15797, Q16636	Gene names	SMAD1, BSP1, MADH1, MADR1
Domain Architecture
Description	Mothers against decapentaplegic homolog 1 (SMAD 1) (Mothers against DPP homolog 1) (Mad-related protein 1) (Transforming growth factor- beta signaling protein 1) (BSP-1) (hSMAD1) (JV4-1).

SMAD4_HUMAN
NC score	0.909937 (rank : 11)	θ value	1.2411e-41 (rank : 11)
Query Neighborhood Hits	25	Target Neighborhood Hits	72	Shared Neighborhood Hits	16
SwissProt Accessions	Q13485	Gene names	SMAD4, DPC4, MADH4
Domain Architecture
Description	Mothers against decapentaplegic homolog 4 (SMAD 4) (Mothers against DPP homolog 4) (Deletion target in pancreatic carcinoma 4) (hSMAD4).

SMAD4_MOUSE
NC score	0.906762 (rank : 12)	θ value	1.2411e-41 (rank : 12)
Query Neighborhood Hits	25	Target Neighborhood Hits	101	Shared Neighborhood Hits	16
SwissProt Accessions	P97471, Q9CW56	Gene names	Smad4, Dpc4, Madh4
Domain Architecture
Description	Mothers against decapentaplegic homolog 4 (SMAD 4) (Mothers against DPP homolog 4) (Deletion target in pancreatic carcinoma 4 homolog) (Smad4).

SMAD6_MOUSE
NC score	0.812617 (rank : 13)	θ value	7.06379e-29 (rank : 13)
Query Neighborhood Hits	25	Target Neighborhood Hits	22	Shared Neighborhood Hits	16
SwissProt Accessions	O35182, Q9CW62	Gene names	Smad6, Madh6, Madh7, Msmad6
Domain Architecture
Description	Mothers against decapentaplegic homolog 6 (SMAD 6) (Mothers against DPP homolog 6) (Smad6) (Mad homolog 7).

SMAD6_HUMAN
NC score	0.810357 (rank : 14)	θ value	1.2049e-28 (rank : 14)
Query Neighborhood Hits	25	Target Neighborhood Hits	31	Shared Neighborhood Hits	16
SwissProt Accessions	O43541, O43654, Q15799, Q9UKZ3	Gene names	SMAD6, MADH6
Domain Architecture
Description	Mothers against decapentaplegic homolog 6 (SMAD 6) (Mothers against DPP homolog 6) (Smad6) (hSMAD6).

SMAD7_MOUSE
NC score	0.799806 (rank : 15)	θ value	1.24688e-25 (rank : 16)
Query Neighborhood Hits	25	Target Neighborhood Hits	18	Shared Neighborhood Hits	16
SwissProt Accessions	O35253, O88709	Gene names	Smad7, Madh7
Domain Architecture
Description	Mothers against decapentaplegic homolog 7 (SMAD 7) (Mothers against DPP homolog 7) (Smad7) (Madh8).

SMAD7_HUMAN
NC score	0.798995 (rank : 16)	θ value	1.24688e-25 (rank : 15)
Query Neighborhood Hits	25	Target Neighborhood Hits	20	Shared Neighborhood Hits	16
SwissProt Accessions	O15105, O14740, Q6DK23	Gene names	SMAD7, MADH7, MADH8
Domain Architecture
Description	Mothers against decapentaplegic homolog 7 (SMAD 7) (Mothers against DPP homolog 7) (Smad7) (hSMAD7).

CRSP2_HUMAN
NC score	0.063079 (rank : 17)	θ value	θ > 10 (rank : 26)
Query Neighborhood Hits	25	Target Neighborhood Hits	380	Shared Neighborhood Hits	5
SwissProt Accessions	O60244, Q9UNB3	Gene names	CRSP2, ARC150, DRIP150, EXLM1, TRAP170
Domain Architecture	No domain graphic available
Description	CRSP complex subunit 2 (Cofactor required for Sp1 transcriptional activation subunit 2) (Transcriptional coactivator CRSP150) (Vitamin D3 receptor-interacting protein complex 150 kDa component) (DRIP150) (Thyroid hormone receptor-associated protein complex 170 kDa component) (Trap170) (Activator-recruited cofactor 150 kDa component) (ARC150).

NU214_HUMAN
NC score	0.025027 (rank : 18)	θ value	0.62314 (rank : 17)
Query Neighborhood Hits	25	Target Neighborhood Hits	657	Shared Neighborhood Hits	4
SwissProt Accessions	P35658	Gene names	NUP214, CAIN, CAN
Domain Architecture
Description	Nuclear pore complex protein Nup214 (Nucleoporin Nup214) (214 kDa nucleoporin) (CAN protein).

RBNS5_HUMAN
NC score	0.017136 (rank : 19)	θ value	2.36792 (rank : 20)
Query Neighborhood Hits	25	Target Neighborhood Hits	242	Shared Neighborhood Hits	3
SwissProt Accessions	Q9H1K0, Q3KP30, Q59EY8, Q8NAQ1	Gene names	ZFYVE20
Domain Architecture	No domain graphic available
Description	Rabenosyn-5 (FYVE finger-containing Rab5 effector protein rabenosyn-5) (Zinc finger FYVE domain-containing protein 20) (110 kDa protein).

PTN21_MOUSE
NC score	0.011371 (rank : 20)	θ value	0.813845 (rank : 18)
Query Neighborhood Hits	25	Target Neighborhood Hits	155	Shared Neighborhood Hits	5
SwissProt Accessions	Q62136	Gene names	Ptpn21
Domain Architecture
Description	Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase PTP-RL10).

GAB1_HUMAN
NC score	0.010237 (rank : 21)	θ value	5.27518 (rank : 22)
Query Neighborhood Hits	25	Target Neighborhood Hits	279	Shared Neighborhood Hits	4
SwissProt Accessions	Q13480, Q4W5G2, Q6P1W2	Gene names	GAB1
Domain Architecture
Description	GRB2-associated-binding protein 1 (GRB2-associated binder 1).

ITAX_HUMAN
NC score	0.010035 (rank : 22)	θ value	4.03905 (rank : 21)
Query Neighborhood Hits	25	Target Neighborhood Hits	81	Shared Neighborhood Hits	5
SwissProt Accessions	P20702, Q8IVA6	Gene names	ITGAX, CD11C
Domain Architecture
Description	Integrin alpha-X precursor (Leukocyte adhesion glycoprotein p150,95 alpha chain) (Leukocyte adhesion receptor p150,95) (Leu M5) (CD11c antigen).

IKBE_HUMAN
NC score	0.008242 (rank : 23)	θ value	2.36792 (rank : 19)
Query Neighborhood Hits	25	Target Neighborhood Hits	288	Shared Neighborhood Hits	3
SwissProt Accessions	O00221	Gene names	NFKBIE, IKBE
Domain Architecture
Description	NF-kappa-B inhibitor epsilon (NF-kappa-BIE) (I-kappa-B-epsilon) (IkappaBepsilon) (IKB-epsilon) (IKBE).

UB7I1_MOUSE
NC score	0.007744 (rank : 24)	θ value	8.99809 (rank : 25)
Query Neighborhood Hits	25	Target Neighborhood Hits	206	Shared Neighborhood Hits	3
SwissProt Accessions	P58283, Q3U493, Q3UE56, Q3UGM3, Q68FN0, Q6P1H8, Q6PWY5, Q8BN27, Q8C1U3	Gene names	Ubce7ip1, Triad3, Uip83, Zin
Domain Architecture	No domain graphic available
Description	E3 ubiquitin ligase TRIAD3 (EC 6.3.2.-) (Ubiquitin-conjugating enzyme 7-interacting protein 1) (UbcM4-interacting protein 83) (Triad domain- containing protein 3).

PKP4_MOUSE
NC score	0.005954 (rank : 25)	θ value	6.88961 (rank : 23)
Query Neighborhood Hits	25	Target Neighborhood Hits	129	Shared Neighborhood Hits	3
SwissProt Accessions	Q68FH0, Q640N0, Q68G56, Q8BK47, Q8BVH1, Q9CRE3	Gene names	Pkp4, Armrp
Domain Architecture	No domain graphic available
Description	Plakophilin-4 (Armadillo-related protein).

ZEP1_HUMAN
NC score	0.000495 (rank : 26)	θ value	6.88961 (rank : 24)
Query Neighborhood Hits	25	Target Neighborhood Hits	1036	Shared Neighborhood Hits	5
SwissProt Accessions	P15822, Q14122	Gene names	HIVEP1, ZNF40
Domain Architecture	No domain graphic available
Description	Zinc finger protein 40 (Human immunodeficiency virus type I enhancer- binding protein 1) (HIV-EP1) (Major histocompatibility complex-binding protein 1) (MBP-1) (Positive regulatory domain II-binding factor 1) (PRDII-BF1).