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Network neighborhood for query Sequence : RGAP1_MOUSE

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RGAP1_MOUSE
SwissProt Accessions	Q9WVM1, Q3THR5, Q3TI41, Q3TM81	Gene names	Racgap1, Mgcracgap
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

RGAP1_HUMAN
θ value	0 (rank : 1)	NC score	0.981980 (rank : 2)
Query Neighborhood Hits	185	Target Neighborhood Hits	189	Shared Neighborhood Hits	126
SwissProt Accessions	Q9H0H5, Q6PJ26, Q9NWN2, Q9P250, Q9P2W2	Gene names	RACGAP1, KIAA1478, MGCRACGAP
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

RGAP1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	185	Target Neighborhood Hits	185	Shared Neighborhood Hits	185
SwissProt Accessions	Q9WVM1, Q3THR5, Q3TI41, Q3TM81	Gene names	Racgap1, Mgcracgap
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

CHIN_MOUSE
θ value	1.85889e-29 (rank : 3)	NC score	0.793956 (rank : 7)
Query Neighborhood Hits	185	Target Neighborhood Hits	229	Shared Neighborhood Hits	95
SwissProt Accessions	Q91V57, Q3UGY3, Q7TQE5, Q8BWU6, Q9D9B3	Gene names	Chn1, Arhgap2
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

CHIN_HUMAN
θ value	7.06379e-29 (rank : 4)	NC score	0.790710 (rank : 8)
Query Neighborhood Hits	185	Target Neighborhood Hits	227	Shared Neighborhood Hits	94
SwissProt Accessions	P15882, Q53SD6, Q53SH5, Q96FB0	Gene names	CHN1, ARHGAP2, CHN
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

CHIO_MOUSE
θ value	3.28125e-26 (rank : 5)	NC score	0.818720 (rank : 3)
Query Neighborhood Hits	185	Target Neighborhood Hits	130	Shared Neighborhood Hits	94
SwissProt Accessions	Q80XD1, Q9D9W2, Q9ER57	Gene names	Chn2, Arhgap3, Bch
Domain Architecture	No domain graphic available
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

CHIO_HUMAN
θ value	9.54697e-26 (rank : 6)	NC score	0.786580 (rank : 9)
Query Neighborhood Hits	185	Target Neighborhood Hits	220	Shared Neighborhood Hits	94
SwissProt Accessions	P52757, Q75MM2	Gene names	CHN2, ARHGAP3, BCH
Domain Architecture
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

MYO9B_HUMAN
θ value	3.07116e-24 (rank : 7)	NC score	0.442724 (rank : 58)
Query Neighborhood Hits	185	Target Neighborhood Hits	641	Shared Neighborhood Hits	105
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

MYO9B_MOUSE
θ value	6.84181e-24 (rank : 8)	NC score	0.448200 (rank : 57)
Query Neighborhood Hits	185	Target Neighborhood Hits	311	Shared Neighborhood Hits	101
SwissProt Accessions	Q9QY06, Q9QY07, Q9QY08, Q9QY09	Gene names	Myo9b, Myr5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

ABR_HUMAN
θ value	1.09232e-21 (rank : 9)	NC score	0.733942 (rank : 28)
Query Neighborhood Hits	185	Target Neighborhood Hits	166	Shared Neighborhood Hits	69
SwissProt Accessions	Q12979, Q13693, Q13694	Gene names	ABR
Domain Architecture
Description	Active breakpoint cluster region-related protein.

RHG26_HUMAN
θ value	7.82807e-20 (rank : 10)	NC score	0.738101 (rank : 24)
Query Neighborhood Hits	185	Target Neighborhood Hits	281	Shared Neighborhood Hits	72
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

OPHN1_HUMAN
θ value	2.13179e-17 (rank : 11)	NC score	0.770944 (rank : 12)
Query Neighborhood Hits	185	Target Neighborhood Hits	161	Shared Neighborhood Hits	70
SwissProt Accessions	O60890, Q5JQ81, Q8WX47	Gene names	OPHN1
Domain Architecture
Description	Oligophrenin 1.

OPHN1_MOUSE
θ value	3.63628e-17 (rank : 12)	NC score	0.767090 (rank : 15)
Query Neighborhood Hits	185	Target Neighborhood Hits	174	Shared Neighborhood Hits	68
SwissProt Accessions	Q99J31, Q544K7	Gene names	Ophn1
Domain Architecture
Description	Oligophrenin 1.

RBP1_MOUSE
θ value	3.63628e-17 (rank : 13)	NC score	0.734601 (rank : 27)
Query Neighborhood Hits	185	Target Neighborhood Hits	493	Shared Neighborhood Hits	107
SwissProt Accessions	Q62172, Q9CRE5	Gene names	Ralbp1, Rip1
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

BCR_HUMAN
θ value	1.80466e-16 (rank : 14)	NC score	0.717550 (rank : 31)
Query Neighborhood Hits	185	Target Neighborhood Hits	204	Shared Neighborhood Hits	68
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

RHG12_HUMAN
θ value	1.80466e-16 (rank : 15)	NC score	0.785558 (rank : 10)
Query Neighborhood Hits	185	Target Neighborhood Hits	190	Shared Neighborhood Hits	64
SwissProt Accessions	Q8IWW6, Q86UB3, Q8IWW7, Q8N3L1, Q9NT76	Gene names	ARHGAP12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

TCGAP_HUMAN
θ value	2.35696e-16 (rank : 16)	NC score	0.668923 (rank : 37)
Query Neighborhood Hits	185	Target Neighborhood Hits	872	Shared Neighborhood Hits	67
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

TCGAP_MOUSE
θ value	2.35696e-16 (rank : 17)	NC score	0.754107 (rank : 18)
Query Neighborhood Hits	185	Target Neighborhood Hits	409	Shared Neighborhood Hits	67
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

RHG12_MOUSE
θ value	3.07829e-16 (rank : 18)	NC score	0.781264 (rank : 11)
Query Neighborhood Hits	185	Target Neighborhood Hits	204	Shared Neighborhood Hits	62
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

GMIP_HUMAN
θ value	4.02038e-16 (rank : 19)	NC score	0.800940 (rank : 6)
Query Neighborhood Hits	185	Target Neighborhood Hits	225	Shared Neighborhood Hits	87
SwissProt Accessions	Q9P107	Gene names	GMIP
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

CEND2_HUMAN
θ value	5.25075e-16 (rank : 20)	NC score	0.634497 (rank : 42)
Query Neighborhood Hits	185	Target Neighborhood Hits	166	Shared Neighborhood Hits	59
SwissProt Accessions	Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71	Gene names	CENTD2, ARAP1, KIAA0782
Domain Architecture
Description	Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).

RBP1_HUMAN
θ value	6.85773e-16 (rank : 21)	NC score	0.717782 (rank : 30)
Query Neighborhood Hits	185	Target Neighborhood Hits	521	Shared Neighborhood Hits	108
SwissProt Accessions	Q15311	Gene names	RALBP1, RLIP1, RLIP76
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

GMIP_MOUSE
θ value	2.60593e-15 (rank : 22)	NC score	0.803061 (rank : 5)
Query Neighborhood Hits	185	Target Neighborhood Hits	202	Shared Neighborhood Hits	90
SwissProt Accessions	Q6PGG2, Q6P9S3	Gene names	Gmip
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

RHG05_HUMAN
θ value	1.68911e-14 (rank : 23)	NC score	0.736999 (rank : 25)
Query Neighborhood Hits	185	Target Neighborhood Hits	158	Shared Neighborhood Hits	66
SwissProt Accessions	Q13017	Gene names	ARHGAP5, RHOGAP5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

RHG25_MOUSE
θ value	3.76295e-14 (rank : 24)	NC score	0.713883 (rank : 32)
Query Neighborhood Hits	185	Target Neighborhood Hits	492	Shared Neighborhood Hits	88
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RHG05_MOUSE
θ value	4.91457e-14 (rank : 25)	NC score	0.741957 (rank : 22)
Query Neighborhood Hits	185	Target Neighborhood Hits	165	Shared Neighborhood Hits	69
SwissProt Accessions	P97393	Gene names	Arhgap5, Rhogap5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

RHG25_HUMAN
θ value	4.91457e-14 (rank : 26)	NC score	0.696405 (rank : 33)
Query Neighborhood Hits	185	Target Neighborhood Hits	550	Shared Neighborhood Hits	101
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

GRLF1_HUMAN
θ value	2.43908e-13 (rank : 27)	NC score	0.762676 (rank : 16)
Query Neighborhood Hits	185	Target Neighborhood Hits	167	Shared Neighborhood Hits	62
SwissProt Accessions	Q9NRY4, Q14452, Q9C0E1	Gene names	GRLF1, GRF1, KIAA1722
Domain Architecture
Description	Glucocorticoid receptor DNA-binding factor 1 (Glucocorticoid receptor repression factor 1) (GRF-1) (Rho GAP p190A) (p190-A).

RHG09_HUMAN
θ value	9.26847e-13 (rank : 28)	NC score	0.811033 (rank : 4)
Query Neighborhood Hits	185	Target Neighborhood Hits	186	Shared Neighborhood Hits	67
SwissProt Accessions	Q9BRR9, Q8TCJ3, Q8WYR0, Q96EZ2, Q96S74	Gene names	ARHGAP9
Domain Architecture
Description	Rho-GTPase-activating protein 9.

RHG01_HUMAN
θ value	1.2105e-12 (rank : 29)	NC score	0.748407 (rank : 21)
Query Neighborhood Hits	185	Target Neighborhood Hits	75	Shared Neighborhood Hits	61
SwissProt Accessions	Q07960	Gene names	ARHGAP1, CDC42GAP, RHOGAP1
Domain Architecture
Description	Rho-GTPase-activating protein 1 (GTPase-activating protein rhoOGAP) (Rho-related small GTPase protein activator) (CDC42 GTPase-activating protein) (p50-RhoGAP).

3BP1_HUMAN
θ value	1.58096e-12 (rank : 30)	NC score	0.751045 (rank : 19)
Query Neighborhood Hits	185	Target Neighborhood Hits	376	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

SRGP2_HUMAN
θ value	1.58096e-12 (rank : 31)	NC score	0.672533 (rank : 35)
Query Neighborhood Hits	185	Target Neighborhood Hits	331	Shared Neighborhood Hits	81
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

RHG06_MOUSE
θ value	2.0648e-12 (rank : 32)	NC score	0.768111 (rank : 14)
Query Neighborhood Hits	185	Target Neighborhood Hits	105	Shared Neighborhood Hits	62
SwissProt Accessions	O54834, Q9QZL8	Gene names	Arhgap6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

CEND3_MOUSE
θ value	2.69671e-12 (rank : 33)	NC score	0.595648 (rank : 47)
Query Neighborhood Hits	185	Target Neighborhood Hits	228	Shared Neighborhood Hits	61
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

RHG06_HUMAN
θ value	2.69671e-12 (rank : 34)	NC score	0.768998 (rank : 13)
Query Neighborhood Hits	185	Target Neighborhood Hits	114	Shared Neighborhood Hits	62
SwissProt Accessions	O43182, O43437, Q9P1B3, Q9UK81, Q9UK82	Gene names	ARHGAP6, RHOGAP6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

RHG08_HUMAN
θ value	2.69671e-12 (rank : 35)	NC score	0.731592 (rank : 29)
Query Neighborhood Hits	185	Target Neighborhood Hits	88	Shared Neighborhood Hits	61
SwissProt Accessions	Q9NSG0, O75983, O95695, Q96RW1, Q96RW2, Q9HA49, Q9HC46, Q9NVX8, Q9NXL1, Q9UH20	Gene names	ARHGAP8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

RHG08_MOUSE
θ value	2.69671e-12 (rank : 36)	NC score	0.735788 (rank : 26)
Query Neighborhood Hits	185	Target Neighborhood Hits	73	Shared Neighborhood Hits	61
SwissProt Accessions	Q9CXP4, Q99JY7	Gene names	Arhgap8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

SRGP2_MOUSE
θ value	6.00763e-12 (rank : 37)	NC score	0.664682 (rank : 39)
Query Neighborhood Hits	185	Target Neighborhood Hits	324	Shared Neighborhood Hits	81
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

CEND1_MOUSE
θ value	1.74796e-11 (rank : 38)	NC score	0.548346 (rank : 54)
Query Neighborhood Hits	185	Target Neighborhood Hits	260	Shared Neighborhood Hits	62
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

CEND3_HUMAN
θ value	1.133e-10 (rank : 39)	NC score	0.584230 (rank : 49)
Query Neighborhood Hits	185	Target Neighborhood Hits	275	Shared Neighborhood Hits	61
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

SRGP1_HUMAN
θ value	1.133e-10 (rank : 40)	NC score	0.658841 (rank : 40)
Query Neighborhood Hits	185	Target Neighborhood Hits	390	Shared Neighborhood Hits	86
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

RHG04_HUMAN
θ value	1.47974e-10 (rank : 41)	NC score	0.681466 (rank : 34)
Query Neighborhood Hits	185	Target Neighborhood Hits	307	Shared Neighborhood Hits	73
SwissProt Accessions	P98171, Q14144	Gene names	ARHGAP4, KIAA0131, RGC1, RHOGAP4
Domain Architecture
Description	Rho-GTPase-activating protein 4 (Rho-GAP hematopoietic protein C1) (p115).

RHG18_MOUSE
θ value	3.29651e-10 (rank : 42)	NC score	0.740276 (rank : 23)
Query Neighborhood Hits	185	Target Neighborhood Hits	110	Shared Neighborhood Hits	64
SwissProt Accessions	Q8K0Q5, Q8BP03, Q8R196	Gene names	Arhgap18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18.

RHG18_HUMAN
θ value	4.30538e-10 (rank : 43)	NC score	0.750594 (rank : 20)
Query Neighborhood Hits	185	Target Neighborhood Hits	90	Shared Neighborhood Hits	61
SwissProt Accessions	Q8N392, Q58EZ3, Q6P679, Q6PJD7, Q96S64	Gene names	ARHGAP18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18 (MacGAP).

CEND1_HUMAN
θ value	2.13673e-09 (rank : 44)	NC score	0.524491 (rank : 56)
Query Neighborhood Hits	185	Target Neighborhood Hits	284	Shared Neighborhood Hits	60
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

3BP1_MOUSE
θ value	2.79066e-09 (rank : 45)	NC score	0.758512 (rank : 17)
Query Neighborhood Hits	185	Target Neighborhood Hits	238	Shared Neighborhood Hits	64
SwissProt Accessions	P55194, Q99KK8	Gene names	Sh3bp1, 3bp1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

FNBP2_HUMAN
θ value	6.21693e-09 (rank : 46)	NC score	0.651493 (rank : 41)
Query Neighborhood Hits	185	Target Neighborhood Hits	432	Shared Neighborhood Hits	91
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

CE005_HUMAN
θ value	1.06045e-08 (rank : 47)	NC score	0.620878 (rank : 44)
Query Neighborhood Hits	185	Target Neighborhood Hits	213	Shared Neighborhood Hits	76
SwissProt Accessions	Q9NYF5, Q6PGQ2, Q9P0I7	Gene names	C5orf5
Domain Architecture
Description	Protein C5orf5 (GAP-like protein N61).

CE005_MOUSE
θ value	2.36244e-08 (rank : 48)	NC score	0.617749 (rank : 45)
Query Neighborhood Hits	185	Target Neighborhood Hits	238	Shared Neighborhood Hits	80
SwissProt Accessions	Q8K2H3	Gene names
Domain Architecture
Description	Protein C5orf5 homolog.

K1688_HUMAN
θ value	6.87365e-08 (rank : 49)	NC score	0.544090 (rank : 55)
Query Neighborhood Hits	185	Target Neighborhood Hits	217	Shared Neighborhood Hits	59
SwissProt Accessions	Q9C0H5	Gene names	KIAA1688
Domain Architecture
Description	Protein KIAA1688.

TAGAP_HUMAN
θ value	1.17247e-07 (rank : 50)	NC score	0.668909 (rank : 38)
Query Neighborhood Hits	185	Target Neighborhood Hits	82	Shared Neighborhood Hits	60
SwissProt Accessions	Q8N103, Q2NKM8, Q8NI40, Q96KZ2, Q96QA2	Gene names	TAGAP, TAGAP1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

K1688_MOUSE
θ value	1.53129e-07 (rank : 51)	NC score	0.555543 (rank : 52)
Query Neighborhood Hits	185	Target Neighborhood Hits	188	Shared Neighborhood Hits	58
SwissProt Accessions	P59281, Q69ZD4, Q6P9R6	Gene names	Kiaa1688, D15Wsu169e
Domain Architecture	No domain graphic available
Description	Protein KIAA1688.

RHG07_HUMAN
θ value	1.99992e-07 (rank : 52)	NC score	0.616869 (rank : 46)
Query Neighborhood Hits	185	Target Neighborhood Hits	108	Shared Neighborhood Hits	62
SwissProt Accessions	Q96QB1, O14868, O43199, Q9C0E0	Gene names	DLC1, ARHGAP7, KIAA1723, STARD12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein) (Dlc-1) (HP protein) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

RHG07_MOUSE
θ value	1.99992e-07 (rank : 53)	NC score	0.621123 (rank : 43)
Query Neighborhood Hits	185	Target Neighborhood Hits	103	Shared Neighborhood Hits	61
SwissProt Accessions	Q9R0Z9, Q8R541	Gene names	Dlc1, Arhgap7, Stard12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein homolog) (Dlc-1) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

STAR8_HUMAN
θ value	4.45536e-07 (rank : 54)	NC score	0.579462 (rank : 50)
Query Neighborhood Hits	185	Target Neighborhood Hits	216	Shared Neighborhood Hits	59
SwissProt Accessions	Q92502, Q5JST0	Gene names	STARD8, KIAA0189
Domain Architecture
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

STAR8_MOUSE
θ value	1.29631e-06 (rank : 55)	NC score	0.584488 (rank : 48)
Query Neighborhood Hits	185	Target Neighborhood Hits	101	Shared Neighborhood Hits	58
SwissProt Accessions	Q8K031, Q3UZC7, Q6A0A8, Q6P5E0, Q8R3X8	Gene names	Stard8, Kiaa0189
Domain Architecture	No domain graphic available
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

P85A_HUMAN
θ value	2.21117e-06 (rank : 56)	NC score	0.395640 (rank : 59)
Query Neighborhood Hits	185	Target Neighborhood Hits	479	Shared Neighborhood Hits	91
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

TAGAP_MOUSE
θ value	6.43352e-06 (rank : 57)	NC score	0.672007 (rank : 36)
Query Neighborhood Hits	185	Target Neighborhood Hits	83	Shared Neighborhood Hits	59
SwissProt Accessions	Q8K2L9, Q920D6	Gene names	Tagap, Tagap1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

P85A_MOUSE
θ value	1.43324e-05 (rank : 58)	NC score	0.386137 (rank : 60)
Query Neighborhood Hits	185	Target Neighborhood Hits	435	Shared Neighborhood Hits	84
SwissProt Accessions	P26450	Gene names	Pik3r1
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

STA13_MOUSE
θ value	0.00228821 (rank : 59)	NC score	0.553601 (rank : 53)
Query Neighborhood Hits	185	Target Neighborhood Hits	89	Shared Neighborhood Hits	58
SwissProt Accessions	Q923Q2, Q8K369	Gene names	Stard13
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13).

STA13_HUMAN
θ value	0.00298849 (rank : 60)	NC score	0.563339 (rank : 51)
Query Neighborhood Hits	185	Target Neighborhood Hits	89	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Y3M8, Q5HYH1, Q5TAE3, Q6UN61, Q86TP6, Q86WQ3, Q86XT1	Gene names	STARD13, DLC2, GT650
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13) (46H23.2) (Deleted in liver cancer protein 2) (Rho GTPase-activating protein).

CTRO_MOUSE
θ value	0.00509761 (rank : 61)	NC score	0.051576 (rank : 206)
Query Neighborhood Hits	185	Target Neighborhood Hits	2344	Shared Neighborhood Hits	118
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

KPCD2_HUMAN
θ value	0.0113563 (rank : 62)	NC score	0.049586 (rank : 233)
Query Neighborhood Hits	185	Target Neighborhood Hits	910	Shared Neighborhood Hits	50
SwissProt Accessions	Q9BZL6, Q8TB08, Q9P0T6, Q9Y3X8	Gene names	PRKD2, PKD2
Domain Architecture
Description	Serine/threonine-protein kinase D2 (EC 2.7.11.13) (nPKC-D2).

CTRO_HUMAN
θ value	0.0148317 (rank : 63)	NC score	0.047814 (rank : 237)
Query Neighborhood Hits	185	Target Neighborhood Hits	2092	Shared Neighborhood Hits	110
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

REST_HUMAN
θ value	0.0148317 (rank : 64)	NC score	0.061774 (rank : 122)
Query Neighborhood Hits	185	Target Neighborhood Hits	1605	Shared Neighborhood Hits	82
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

CENPF_HUMAN
θ value	0.0193708 (rank : 65)	NC score	0.064776 (rank : 103)
Query Neighborhood Hits	185	Target Neighborhood Hits	1932	Shared Neighborhood Hits	96
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

KPCD1_HUMAN
θ value	0.0193708 (rank : 66)	NC score	0.051325 (rank : 213)
Query Neighborhood Hits	185	Target Neighborhood Hits	901	Shared Neighborhood Hits	50
SwissProt Accessions	Q15139	Gene names	PRKD1, PKD, PKD1, PRKCM
Domain Architecture
Description	Serine/threonine-protein kinase D1 (EC 2.7.11.13) (nPKC-D1) (Protein kinase D) (Protein kinase C mu type) (nPKC-mu).

KPCD1_MOUSE
θ value	0.0330416 (rank : 67)	NC score	0.050971 (rank : 217)
Query Neighborhood Hits	185	Target Neighborhood Hits	891	Shared Neighborhood Hits	50
SwissProt Accessions	Q62101	Gene names	Prkd1, Pkcm, Pkd, Prkcm
Domain Architecture
Description	Serine/threonine-protein kinase D1 (EC 2.7.11.13) (nPKC-D1) (Protein kinase D) (Protein kinase C mu type) (nPKC-mu).

KSR2_HUMAN
θ value	0.0431538 (rank : 68)	NC score	0.034197 (rank : 263)
Query Neighborhood Hits	185	Target Neighborhood Hits	920	Shared Neighborhood Hits	45
SwissProt Accessions	Q6VAB6, Q8N775	Gene names	KSR2
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-2 (hKSR2).

RGNEF_MOUSE
θ value	0.0431538 (rank : 69)	NC score	0.077567 (rank : 82)
Query Neighborhood Hits	185	Target Neighborhood Hits	641	Shared Neighborhood Hits	82
SwissProt Accessions	P97433	Gene names	Rgnef, Rhoip2
Domain Architecture
Description	Rho-guanine nucleotide exchange factor (Rho-interacting protein 2) (RhoGEF) (RIP2).

GRP3_HUMAN
θ value	0.0736092 (rank : 70)	NC score	0.161910 (rank : 63)
Query Neighborhood Hits	185	Target Neighborhood Hits	131	Shared Neighborhood Hits	46
SwissProt Accessions	Q8IV61, O94931	Gene names	RASGRP3, GRP3, KIAA0846
Domain Architecture
Description	RAS guanyl-releasing protein 3 (Calcium and DAG-regulated guanine nucleotide exchange factor III) (Guanine nucleotide exchange factor for Rap1).

DGKQ_HUMAN
θ value	0.163984 (rank : 71)	NC score	0.096338 (rank : 66)
Query Neighborhood Hits	185	Target Neighborhood Hits	131	Shared Neighborhood Hits	41
SwissProt Accessions	P52824	Gene names	DGKQ, DAGK4
Domain Architecture
Description	Diacylglycerol kinase theta (EC 2.7.1.107) (Diglyceride kinase theta) (DGK-theta) (DAG kinase theta).

CO4A2_HUMAN
θ value	0.21417 (rank : 72)	NC score	0.005841 (rank : 300)
Query Neighborhood Hits	185	Target Neighborhood Hits	454	Shared Neighborhood Hits	6
SwissProt Accessions	P08572	Gene names	COL4A2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

KPCD3_HUMAN
θ value	0.21417 (rank : 73)	NC score	0.051830 (rank : 201)
Query Neighborhood Hits	185	Target Neighborhood Hits	895	Shared Neighborhood Hits	50
SwissProt Accessions	O94806	Gene names	PRKD3, EPK2, PRKCN
Domain Architecture
Description	Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) (nPKC-nu) (Protein kinase EPK2).

MY18A_HUMAN
θ value	0.21417 (rank : 74)	NC score	0.073603 (rank : 87)
Query Neighborhood Hits	185	Target Neighborhood Hits	1929	Shared Neighborhood Hits	93
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

SMC2_MOUSE
θ value	0.21417 (rank : 75)	NC score	0.057283 (rank : 155)
Query Neighborhood Hits	185	Target Neighborhood Hits	1131	Shared Neighborhood Hits	72
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

ITSN1_HUMAN
θ value	0.279714 (rank : 76)	NC score	0.077876 (rank : 81)
Query Neighborhood Hits	185	Target Neighborhood Hits	1757	Shared Neighborhood Hits	99
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

KPCD3_MOUSE
θ value	0.279714 (rank : 77)	NC score	0.050699 (rank : 223)
Query Neighborhood Hits	185	Target Neighborhood Hits	901	Shared Neighborhood Hits	50
SwissProt Accessions	Q8K1Y2	Gene names	Prkd3, Prkcn
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) (nPKC-nu).

MRIP_MOUSE
θ value	0.279714 (rank : 78)	NC score	0.060533 (rank : 130)
Query Neighborhood Hits	185	Target Neighborhood Hits	569	Shared Neighborhood Hits	53
SwissProt Accessions	P97434, Q3TBR5, Q3TC85, Q3TRS0, Q3U1Y8, Q3U3E4, Q5SWZ3, Q5SWZ4, Q5SWZ7, Q6P559, Q80YC8	Gene names	Mrip, Kiaa0864, Rhoip3
Domain Architecture
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (p116Rip) (RIP3).

RASF5_HUMAN
θ value	0.279714 (rank : 79)	NC score	0.092575 (rank : 68)
Query Neighborhood Hits	185	Target Neighborhood Hits	79	Shared Neighborhood Hits	32
SwissProt Accessions	Q8WWW0, Q5SY32, Q8WWV9, Q8WXF4, Q9BT99	Gene names	RASSF5, NORE1, RAPL
Domain Architecture	No domain graphic available
Description	Ras association domain-containing family protein 5 (New ras effector 1) (Regulator for cell adhesion and polarization enriched in lymphoid tissues) (RAPL).

SM1L2_MOUSE
θ value	0.279714 (rank : 80)	NC score	0.055870 (rank : 167)
Query Neighborhood Hits	185	Target Neighborhood Hits	918	Shared Neighborhood Hits	74
SwissProt Accessions	Q920F6	Gene names	Smc1l2
Domain Architecture
Description	Structural maintenance of chromosomes 1-like 2 protein (SMC1beta protein).

TJAP1_MOUSE
θ value	0.279714 (rank : 81)	NC score	0.046319 (rank : 238)
Query Neighborhood Hits	185	Target Neighborhood Hits	295	Shared Neighborhood Hits	45
SwissProt Accessions	Q9DCD5, Q8CFL7, Q8R5I2	Gene names	Tjap1, Pilt, Tjp4
Domain Architecture	No domain graphic available
Description	Tight junction-associated protein 1 (Tight junction protein 4) (Protein incorporated later into tight junctions).

MRIP_HUMAN
θ value	0.365318 (rank : 82)	NC score	0.060013 (rank : 135)
Query Neighborhood Hits	185	Target Neighborhood Hits	578	Shared Neighborhood Hits	55
SwissProt Accessions	Q6WCQ1, Q3KQZ5, Q5FB94, Q6DHW2, Q7Z5Y2, Q8N390, Q96G40	Gene names	MRIP, KIAA0864, RHOIP3
Domain Architecture	No domain graphic available
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (M-RIP) (RIP3) (p116Rip).

MYH3_HUMAN
θ value	0.365318 (rank : 83)	NC score	0.069319 (rank : 96)
Query Neighborhood Hits	185	Target Neighborhood Hits	1660	Shared Neighborhood Hits	86
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

RABX5_MOUSE
θ value	0.47712 (rank : 84)	NC score	0.027322 (rank : 275)
Query Neighborhood Hits	185	Target Neighborhood Hits	39	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JM13, Q3UIW0	Gene names	Rabgef1, Rabex5
Domain Architecture
Description	Rab5 GDP/GTP exchange factor (Rabex-5).

TAXB1_HUMAN
θ value	0.47712 (rank : 85)	NC score	0.058701 (rank : 146)
Query Neighborhood Hits	185	Target Neighborhood Hits	829	Shared Neighborhood Hits	71
SwissProt Accessions	Q86VP1, O60398, O95770, Q13311, Q9BQG5, Q9UI88	Gene names	TAX1BP1, T6BP
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 (TRAF6-binding protein).

DPOA2_HUMAN
θ value	0.62314 (rank : 86)	NC score	0.027494 (rank : 272)
Query Neighborhood Hits	185	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q14181, Q9BPV3	Gene names	POLA2
Domain Architecture
Description	DNA polymerase subunit alpha B (DNA polymerase alpha 70 kDa subunit).

MY18A_MOUSE
θ value	0.62314 (rank : 87)	NC score	0.071102 (rank : 90)
Query Neighborhood Hits	185	Target Neighborhood Hits	1989	Shared Neighborhood Hits	94
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

SC11A_HUMAN
θ value	0.62314 (rank : 88)	NC score	0.011736 (rank : 294)
Query Neighborhood Hits	185	Target Neighborhood Hits	111	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UI33, Q68K15, Q8NDX3, Q9UHE0, Q9UHM0	Gene names	SCN11A, PN5, SCN12A, SNS2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (Peripheral nerve sodium channel 5) (hNaN).

TPM3_MOUSE
θ value	0.62314 (rank : 89)	NC score	0.062603 (rank : 115)
Query Neighborhood Hits	185	Target Neighborhood Hits	676	Shared Neighborhood Hits	62
SwissProt Accessions	P21107, Q09021, Q60606, Q80SW6, Q9EPW3	Gene names	Tpm3, Tpm-5, Tpm5
Domain Architecture
Description	Tropomyosin alpha-3 chain (Tropomyosin-3) (Tropomyosin gamma).

BPAEA_MOUSE
θ value	0.813845 (rank : 90)	NC score	0.048138 (rank : 236)
Query Neighborhood Hits	185	Target Neighborhood Hits	1480	Shared Neighborhood Hits	75
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CING_HUMAN
θ value	0.813845 (rank : 91)	NC score	0.052545 (rank : 195)
Query Neighborhood Hits	185	Target Neighborhood Hits	1275	Shared Neighborhood Hits	75
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

KPCD_HUMAN
θ value	0.813845 (rank : 92)	NC score	0.042531 (rank : 246)
Query Neighborhood Hits	185	Target Neighborhood Hits	900	Shared Neighborhood Hits	50
SwissProt Accessions	Q05655, Q15144	Gene names	PRKCD
Domain Architecture
Description	Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta).

KSR1_HUMAN
θ value	0.813845 (rank : 93)	NC score	0.026647 (rank : 278)
Query Neighborhood Hits	185	Target Neighborhood Hits	867	Shared Neighborhood Hits	43
SwissProt Accessions	Q8IVT5, Q13476	Gene names	KSR1, KSR
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-1 (Kinase suppressor of ras).

M3K10_HUMAN
θ value	0.813845 (rank : 94)	NC score	0.016846 (rank : 288)
Query Neighborhood Hits	185	Target Neighborhood Hits	1071	Shared Neighborhood Hits	52
SwissProt Accessions	Q02779, Q12761, Q14871	Gene names	MAP3K10, MLK2, MST
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST).

NACAM_MOUSE
θ value	0.813845 (rank : 95)	NC score	0.019653 (rank : 285)
Query Neighborhood Hits	185	Target Neighborhood Hits	1866	Shared Neighborhood Hits	32
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

TPM3_HUMAN
θ value	0.813845 (rank : 96)	NC score	0.061644 (rank : 124)
Query Neighborhood Hits	185	Target Neighborhood Hits	689	Shared Neighborhood Hits	62
SwissProt Accessions	P06753, P12324, Q969Q2, Q9NQH8	Gene names	TPM3
Domain Architecture
Description	Tropomyosin alpha-3 chain (Tropomyosin-3) (Tropomyosin gamma) (hTM5).

BAT2_HUMAN
θ value	1.06291 (rank : 97)	NC score	0.035775 (rank : 259)
Query Neighborhood Hits	185	Target Neighborhood Hits	931	Shared Neighborhood Hits	21
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

CJ118_HUMAN
θ value	1.06291 (rank : 98)	NC score	0.053196 (rank : 188)
Query Neighborhood Hits	185	Target Neighborhood Hits	937	Shared Neighborhood Hits	69
SwissProt Accessions	Q7Z3E2, Q2M2V6, Q6NS91, Q7RTP1, Q8N117, Q8N3G3, Q8N6C2, Q9NWA3	Gene names	C10orf118
Domain Architecture	No domain graphic available
Description	Protein C10orf118 (CTCL tumor antigen HD-CL-01/L14-2).

CROCC_HUMAN
θ value	1.06291 (rank : 99)	NC score	0.055925 (rank : 165)
Query Neighborhood Hits	185	Target Neighborhood Hits	1409	Shared Neighborhood Hits	80
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

PEPL_HUMAN
θ value	1.06291 (rank : 100)	NC score	0.045356 (rank : 240)
Query Neighborhood Hits	185	Target Neighborhood Hits	1141	Shared Neighborhood Hits	74
SwissProt Accessions	O60437, O60314, O60454	Gene names	PPL, KIAA0568
Domain Architecture
Description	Periplakin (195 kDa cornified envelope precursor protein) (190 kDa paraneoplastic pemphigus antigen).

UACA_HUMAN
θ value	1.06291 (rank : 101)	NC score	0.039238 (rank : 250)
Query Neighborhood Hits	185	Target Neighborhood Hits	1622	Shared Neighborhood Hits	78
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

CCD96_HUMAN
θ value	1.38821 (rank : 102)	NC score	0.059725 (rank : 138)
Query Neighborhood Hits	185	Target Neighborhood Hits	595	Shared Neighborhood Hits	60
SwissProt Accessions	Q2M329, Q8N2I7	Gene names	CCDC96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

CCD96_MOUSE
θ value	1.38821 (rank : 103)	NC score	0.055717 (rank : 171)
Query Neighborhood Hits	185	Target Neighborhood Hits	704	Shared Neighborhood Hits	59
SwissProt Accessions	Q9CR92	Gene names	Ccdc96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

FA47B_HUMAN
θ value	1.38821 (rank : 104)	NC score	0.016629 (rank : 289)
Query Neighborhood Hits	185	Target Neighborhood Hits	431	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

GOGA4_HUMAN
θ value	1.38821 (rank : 105)	NC score	0.051372 (rank : 212)
Query Neighborhood Hits	185	Target Neighborhood Hits	2034	Shared Neighborhood Hits	87
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

MOES_HUMAN
θ value	1.38821 (rank : 106)	NC score	0.032051 (rank : 268)
Query Neighborhood Hits	185	Target Neighborhood Hits	892	Shared Neighborhood Hits	68
SwissProt Accessions	P26038	Gene names	MSN
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

OCRL_HUMAN
θ value	1.38821 (rank : 107)	NC score	0.286606 (rank : 61)
Query Neighborhood Hits	185	Target Neighborhood Hits	77	Shared Neighborhood Hits	50
SwissProt Accessions	Q01968, O60800, Q15684, Q15774, Q5JQF1, Q5JQF2, Q9UJG5, Q9UMA5	Gene names	OCRL, INPP5F, OCRL1
Domain Architecture
Description	Inositol polyphosphate 5-phosphatase OCRL-1 (EC 3.1.3.36) (Lowe oculocerebrorenal syndrome protein).

SFR17_HUMAN
θ value	1.38821 (rank : 108)	NC score	0.032832 (rank : 267)
Query Neighborhood Hits	185	Target Neighborhood Hits	325	Shared Neighborhood Hits	31
SwissProt Accessions	Q8TF01, Q5T064, Q6P2B4, Q6P2N4, Q6PJ93, Q6PK36, Q7Z640, Q8TF00, Q96K10, Q96SM5, Q9P076, Q9P0C0, Q9Y4N3	Gene names	SRRP130, C6orf111
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 130 (Serine-arginine-rich- splicing regulatory protein 130) (SRrp130) (SR-rich protein) (SR- related protein).

TPM1_HUMAN
θ value	1.38821 (rank : 109)	NC score	0.063442 (rank : 111)
Query Neighborhood Hits	185	Target Neighborhood Hits	716	Shared Neighborhood Hits	65
SwissProt Accessions	P09493, P09494, P10469, Q86W64, Q96IK2, Q9UCY9	Gene names	TPM1, TMSA
Domain Architecture
Description	Tropomyosin 1 alpha chain (Alpha-tropomyosin).

TPM1_MOUSE
θ value	1.38821 (rank : 110)	NC score	0.062602 (rank : 116)
Query Neighborhood Hits	185	Target Neighborhood Hits	729	Shared Neighborhood Hits	64
SwissProt Accessions	P58771, P02558, P19354, P46902, P99034	Gene names	Tpm1, Tpm-1, Tpma
Domain Architecture
Description	Tropomyosin 1 alpha chain (Alpha-tropomyosin).

CING_MOUSE
θ value	1.81305 (rank : 111)	NC score	0.053326 (rank : 187)
Query Neighborhood Hits	185	Target Neighborhood Hits	1432	Shared Neighborhood Hits	83
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

FLIP1_HUMAN
θ value	1.81305 (rank : 112)	NC score	0.051710 (rank : 204)
Query Neighborhood Hits	185	Target Neighborhood Hits	1405	Shared Neighborhood Hits	76
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

GRAP1_MOUSE
θ value	1.81305 (rank : 113)	NC score	0.045218 (rank : 242)
Query Neighborhood Hits	185	Target Neighborhood Hits	1234	Shared Neighborhood Hits	75
SwissProt Accessions	Q8VD04, O35693, Q3T9C3, Q69ZP9	Gene names	Gripap1, DXImx47e, Kiaa1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1) (HCMV-interacting protein).

KPCD_MOUSE
θ value	1.81305 (rank : 114)	NC score	0.041585 (rank : 248)
Query Neighborhood Hits	185	Target Neighborhood Hits	888	Shared Neighborhood Hits	50
SwissProt Accessions	P28867, Q91V85, Q9Z333	Gene names	Prkcd, Pkcd
Domain Architecture
Description	Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta).

KPCI_MOUSE
θ value	1.81305 (rank : 115)	NC score	0.033762 (rank : 264)
Query Neighborhood Hits	185	Target Neighborhood Hits	888	Shared Neighborhood Hits	50
SwissProt Accessions	Q62074	Gene names	Prkci, Pkcl
Domain Architecture
Description	Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota) (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota).

GOPC_MOUSE
θ value	2.36792 (rank : 116)	NC score	0.015728 (rank : 292)
Query Neighborhood Hits	185	Target Neighborhood Hits	323	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BH60, Q8BSV4, Q920R1, Q9ET11	Gene names	Gopc
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST).

ITSN1_MOUSE
θ value	2.36792 (rank : 117)	NC score	0.073907 (rank : 85)
Query Neighborhood Hits	185	Target Neighborhood Hits	1669	Shared Neighborhood Hits	98
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

ITSN2_MOUSE
θ value	2.36792 (rank : 118)	NC score	0.072235 (rank : 89)
Query Neighborhood Hits	185	Target Neighborhood Hits	1371	Shared Neighborhood Hits	88
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

KPCA_HUMAN
θ value	2.36792 (rank : 119)	NC score	0.039517 (rank : 249)
Query Neighborhood Hits	185	Target Neighborhood Hits	1070	Shared Neighborhood Hits	55
SwissProt Accessions	P17252, Q15137, Q96RE4	Gene names	PRKCA, PKCA, PRKACA
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

KPCA_MOUSE
θ value	2.36792 (rank : 120)	NC score	0.038580 (rank : 253)
Query Neighborhood Hits	185	Target Neighborhood Hits	1067	Shared Neighborhood Hits	55
SwissProt Accessions	P20444	Gene names	Prkca, Pkca
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

KPCI_HUMAN
θ value	2.36792 (rank : 121)	NC score	0.033518 (rank : 265)
Query Neighborhood Hits	185	Target Neighborhood Hits	885	Shared Neighborhood Hits	50
SwissProt Accessions	P41743, Q8WW06	Gene names	PRKCI, DXS1179E
Domain Architecture
Description	Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota) (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota) (PRKC-lambda/iota).

LAMB3_HUMAN
θ value	2.36792 (rank : 122)	NC score	0.013792 (rank : 293)
Query Neighborhood Hits	185	Target Neighborhood Hits	461	Shared Neighborhood Hits	44
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

RASF5_MOUSE
θ value	2.36792 (rank : 123)	NC score	0.079800 (rank : 78)
Query Neighborhood Hits	185	Target Neighborhood Hits	72	Shared Neighborhood Hits	34
SwissProt Accessions	Q5EBH1, O70407, Q6KAR0, Q8C2E8	Gene names	Rassf5, Nore1, Rapl
Domain Architecture	No domain graphic available
Description	Ras association domain-containing family protein 5 (New ras effector 1) (Regulator for cell adhesion and polarization enriched in lymphoid tissues) (RAPL).

ROCK1_MOUSE
θ value	2.36792 (rank : 124)	NC score	0.043809 (rank : 244)
Query Neighborhood Hits	185	Target Neighborhood Hits	2126	Shared Neighborhood Hits	112
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

TAXB1_MOUSE
θ value	2.36792 (rank : 125)	NC score	0.058737 (rank : 145)
Query Neighborhood Hits	185	Target Neighborhood Hits	886	Shared Neighborhood Hits	77
SwissProt Accessions	Q3UKC1, Q91YT6, Q9CVF0, Q9DC45	Gene names	Tax1bp1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 homolog.

TPR_HUMAN
θ value	2.36792 (rank : 126)	NC score	0.052627 (rank : 192)
Query Neighborhood Hits	185	Target Neighborhood Hits	1921	Shared Neighborhood Hits	90
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

ARAF_HUMAN
θ value	3.0926 (rank : 127)	NC score	0.027349 (rank : 274)
Query Neighborhood Hits	185	Target Neighborhood Hits	924	Shared Neighborhood Hits	43
SwissProt Accessions	P10398, P07557, Q5H9B3	Gene names	ARAF, ARAF1, PKS, PKS2
Domain Architecture
Description	A-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (A- raf-1) (Proto-oncogene Pks).

ARAF_MOUSE
θ value	3.0926 (rank : 128)	NC score	0.027554 (rank : 271)
Query Neighborhood Hits	185	Target Neighborhood Hits	874	Shared Neighborhood Hits	42
SwissProt Accessions	P04627, Q99J44, Q9CTT5, Q9D6R6, Q9DBU7	Gene names	Araf, A-raf, Araf1
Domain Architecture
Description	A-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1).

KPCZ_HUMAN
θ value	3.0926 (rank : 129)	NC score	0.034524 (rank : 262)
Query Neighborhood Hits	185	Target Neighborhood Hits	884	Shared Neighborhood Hits	48
SwissProt Accessions	Q05513, Q15207, Q5SYT5, Q969S4	Gene names	PRKCZ, PKC2
Domain Architecture
Description	Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta).

KS6C1_MOUSE
θ value	3.0926 (rank : 130)	NC score	0.019943 (rank : 283)
Query Neighborhood Hits	185	Target Neighborhood Hits	700	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BLK9, Q3UDY3, Q6PDY4, Q8BMQ5, Q8BX49	Gene names	Rps6kc1
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase delta-1 (EC 2.7.11.1) (52 kDa ribosomal protein S6 kinase).

NCOA2_HUMAN
θ value	3.0926 (rank : 131)	NC score	0.007535 (rank : 299)
Query Neighborhood Hits	185	Target Neighborhood Hits	281	Shared Neighborhood Hits	7
SwissProt Accessions	Q15596	Gene names	NCOA2, TIF2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2).

RADI_MOUSE
θ value	3.0926 (rank : 132)	NC score	0.036278 (rank : 257)
Query Neighborhood Hits	185	Target Neighborhood Hits	773	Shared Neighborhood Hits	68
SwissProt Accessions	P26043, Q9QW27	Gene names	Rdx
Domain Architecture
Description	Radixin (ESP10).

RAF1_HUMAN
θ value	3.0926 (rank : 133)	NC score	0.027357 (rank : 273)
Query Neighborhood Hits	185	Target Neighborhood Hits	886	Shared Neighborhood Hits	43
SwissProt Accessions	P04049	Gene names	RAF1, RAF
Domain Architecture
Description	RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf- 1) (C-RAF) (cRaf).

RAF1_MOUSE
θ value	3.0926 (rank : 134)	NC score	0.026983 (rank : 277)
Query Neighborhood Hits	185	Target Neighborhood Hits	886	Shared Neighborhood Hits	43
SwissProt Accessions	Q99N57, Q91WH1	Gene names	Raf1, Craf
Domain Architecture
Description	RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf- 1) (C-RAF) (cRaf).

RN168_MOUSE
θ value	3.0926 (rank : 135)	NC score	0.022678 (rank : 282)
Query Neighborhood Hits	185	Target Neighborhood Hits	440	Shared Neighborhood Hits	34
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

ROCK1_HUMAN
θ value	3.0926 (rank : 136)	NC score	0.042090 (rank : 247)
Query Neighborhood Hits	185	Target Neighborhood Hits	2000	Shared Neighborhood Hits	109
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).

SMC2_HUMAN
θ value	3.0926 (rank : 137)	NC score	0.055891 (rank : 166)
Query Neighborhood Hits	185	Target Neighborhood Hits	1405	Shared Neighborhood Hits	77
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

TEX9_HUMAN
θ value	3.0926 (rank : 138)	NC score	0.050846 (rank : 219)
Query Neighborhood Hits	185	Target Neighborhood Hits	541	Shared Neighborhood Hits	62
SwissProt Accessions	Q8N6V9	Gene names	TEX9
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 9 protein.

TPM2_HUMAN
θ value	3.0926 (rank : 139)	NC score	0.059025 (rank : 141)
Query Neighborhood Hits	185	Target Neighborhood Hits	677	Shared Neighborhood Hits	62
SwissProt Accessions	P07951, P06468, Q13894, Q53FM4, Q5TCU4, Q5TCU7, Q9UH67	Gene names	TPM2, TMSB
Domain Architecture
Description	Tropomyosin beta chain (Tropomyosin 2) (Beta-tropomyosin).

AKAP9_HUMAN
θ value	4.03905 (rank : 140)	NC score	0.048869 (rank : 235)
Query Neighborhood Hits	185	Target Neighborhood Hits	1710	Shared Neighborhood Hits	84
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

CTR9_HUMAN
θ value	4.03905 (rank : 141)	NC score	0.019690 (rank : 284)
Query Neighborhood Hits	185	Target Neighborhood Hits	383	Shared Neighborhood Hits	24
SwissProt Accessions	Q6PD62, Q15015	Gene names	CTR9, KIAA0155, SH2BP1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1).

CYLN2_HUMAN
θ value	4.03905 (rank : 142)	NC score	0.055268 (rank : 174)
Query Neighborhood Hits	185	Target Neighborhood Hits	1004	Shared Neighborhood Hits	76
SwissProt Accessions	Q9UDT6, O14527, O43611	Gene names	CYLN2, KIAA0291, WBSCR4, WSCR4
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115) (Williams-Beuren syndrome chromosome region 4 protein).

DGKA_HUMAN
θ value	4.03905 (rank : 143)	NC score	0.044632 (rank : 243)
Query Neighborhood Hits	185	Target Neighborhood Hits	151	Shared Neighborhood Hits	38
SwissProt Accessions	P23743, O75481, O75482, O75483	Gene names	DGKA, DAGK, DAGK1
Domain Architecture
Description	Diacylglycerol kinase alpha (EC 2.7.1.107) (Diglyceride kinase alpha) (DGK-alpha) (DAG kinase alpha) (80 kDa diacylglycerol kinase).

FLIP1_MOUSE
θ value	4.03905 (rank : 144)	NC score	0.045343 (rank : 241)
Query Neighborhood Hits	185	Target Neighborhood Hits	1176	Shared Neighborhood Hits	72
SwissProt Accessions	Q9CS72	Gene names	Filip1
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

IFT81_HUMAN
θ value	4.03905 (rank : 145)	NC score	0.046058 (rank : 239)
Query Neighborhood Hits	185	Target Neighborhood Hits	893	Shared Neighborhood Hits	72
SwissProt Accessions	Q8WYA0, Q8NB51, Q9BSV2, Q9UNY8	Gene names	IFT81, CDV1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

ITSN2_HUMAN
θ value	4.03905 (rank : 146)	NC score	0.069747 (rank : 94)
Query Neighborhood Hits	185	Target Neighborhood Hits	1173	Shared Neighborhood Hits	77
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

KPCB_HUMAN
θ value	4.03905 (rank : 147)	NC score	0.039091 (rank : 252)
Query Neighborhood Hits	185	Target Neighborhood Hits	1121	Shared Neighborhood Hits	52
SwissProt Accessions	P05771, O43744, P05127, Q15138, Q93060, Q9UE49, Q9UE50, Q9UEH8, Q9UJ30, Q9UJ33	Gene names	PRKCB1, PKCB, PRKCB
Domain Architecture
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

KPCB_MOUSE
θ value	4.03905 (rank : 148)	NC score	0.039125 (rank : 251)
Query Neighborhood Hits	185	Target Neighborhood Hits	1117	Shared Neighborhood Hits	52
SwissProt Accessions	P68404, P04410, P04411	Gene names	Prkcb1, Pkcb, Prkcb
Domain Architecture	No domain graphic available
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

KSR1_MOUSE
θ value	4.03905 (rank : 149)	NC score	0.025623 (rank : 280)
Query Neighborhood Hits	185	Target Neighborhood Hits	870	Shared Neighborhood Hits	40
SwissProt Accessions	Q61097, Q61648, Q78DX8	Gene names	Ksr1, Ksr
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-1 (Kinase suppressor of ras) (mKSR1) (Hb protein).

LAMA4_HUMAN
θ value	4.03905 (rank : 150)	NC score	0.026988 (rank : 276)
Query Neighborhood Hits	185	Target Neighborhood Hits	708	Shared Neighborhood Hits	58
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

MACF1_HUMAN
θ value	4.03905 (rank : 151)	NC score	0.035712 (rank : 260)
Query Neighborhood Hits	185	Target Neighborhood Hits	1341	Shared Neighborhood Hits	78
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

MACF4_HUMAN
θ value	4.03905 (rank : 152)	NC score	0.036412 (rank : 256)
Query Neighborhood Hits	185	Target Neighborhood Hits	1321	Shared Neighborhood Hits	76
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

TPM2_MOUSE
θ value	4.03905 (rank : 153)	NC score	0.058231 (rank : 150)
Query Neighborhood Hits	185	Target Neighborhood Hits	676	Shared Neighborhood Hits	63
SwissProt Accessions	P58774, P02560, P46901	Gene names	Tpm2, Tpm-2
Domain Architecture
Description	Tropomyosin beta chain (Tropomyosin 2) (Beta-tropomyosin).

ZC3H6_MOUSE
θ value	4.03905 (rank : 154)	NC score	0.009740 (rank : 297)
Query Neighborhood Hits	185	Target Neighborhood Hits	239	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BYK8, Q80UK3, Q8C1H1, Q9D604	Gene names	Zc3h6, Zc3hdc6
Domain Architecture
Description	Zinc finger CCCH domain-containing protein 6.

BRAF1_HUMAN
θ value	5.27518 (rank : 155)	NC score	0.025638 (rank : 279)
Query Neighborhood Hits	185	Target Neighborhood Hits	883	Shared Neighborhood Hits	43
SwissProt Accessions	P15056, Q13878, Q9Y6T3	Gene names	BRAF, BRAF1, RAFB1
Domain Architecture
Description	B-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (p94) (v-Raf murine sarcoma viral oncogene homolog B1).

CYLN2_MOUSE
θ value	5.27518 (rank : 156)	NC score	0.058834 (rank : 144)
Query Neighborhood Hits	185	Target Neighborhood Hits	1002	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Z0H8, Q7TSI9, Q8CHU1, Q9EP81	Gene names	Cyln2, Kiaa0291
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115).

DEK_MOUSE
θ value	5.27518 (rank : 157)	NC score	0.019141 (rank : 286)
Query Neighborhood Hits	185	Target Neighborhood Hits	280	Shared Neighborhood Hits	16
SwissProt Accessions	Q7TNV0, Q80VC5, Q8BZV6	Gene names	Dek
Domain Architecture	No domain graphic available
Description	Protein DEK.

DESP_HUMAN
θ value	5.27518 (rank : 158)	NC score	0.054222 (rank : 185)
Query Neighborhood Hits	185	Target Neighborhood Hits	1470	Shared Neighborhood Hits	81
SwissProt Accessions	P15924, O75993, Q14189, Q9UHN4	Gene names	DSP
Domain Architecture
Description	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen).

DGKB_HUMAN
θ value	5.27518 (rank : 159)	NC score	0.064208 (rank : 106)
Query Neighborhood Hits	185	Target Neighborhood Hits	238	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Y6T7, O75241, Q75MF9, Q75MU7, Q86UI5, Q86UM9, Q9UQ29	Gene names	DGKB, DAGK2, KIAA0718
Domain Architecture
Description	Diacylglycerol kinase beta (EC 2.7.1.107) (Diglyceride kinase beta) (DGK-beta) (DAG kinase beta) (90 kDa diacylglycerol kinase).

GCC2_MOUSE
θ value	5.27518 (rank : 160)	NC score	0.049275 (rank : 234)
Query Neighborhood Hits	185	Target Neighborhood Hits	1619	Shared Neighborhood Hits	81
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

KPCZ_MOUSE
θ value	5.27518 (rank : 161)	NC score	0.033195 (rank : 266)
Query Neighborhood Hits	185	Target Neighborhood Hits	882	Shared Neighborhood Hits	47
SwissProt Accessions	Q02956	Gene names	Prkcz, Pkcz
Domain Architecture
Description	Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta).

PRC1_MOUSE
θ value	5.27518 (rank : 162)	NC score	0.029240 (rank : 270)
Query Neighborhood Hits	185	Target Neighborhood Hits	382	Shared Neighborhood Hits	47
SwissProt Accessions	Q99K43, Q8CE25	Gene names	Prc1
Domain Architecture	No domain graphic available
Description	Protein regulator of cytokinesis 1.

AKA12_HUMAN
θ value	6.88961 (rank : 163)	NC score	0.031050 (rank : 269)
Query Neighborhood Hits	185	Target Neighborhood Hits	825	Shared Neighborhood Hits	46
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

ASXL1_HUMAN
θ value	6.88961 (rank : 164)	NC score	0.009803 (rank : 296)
Query Neighborhood Hits	185	Target Neighborhood Hits	260	Shared Neighborhood Hits	10
SwissProt Accessions	Q8IXJ9, Q5JWS9, Q8IYY7, Q9H466, Q9NQF8, Q9UFJ0, Q9UFP8, Q9Y2I4	Gene names	ASXL1, KIAA0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

CROCC_MOUSE
θ value	6.88961 (rank : 165)	NC score	0.051947 (rank : 198)
Query Neighborhood Hits	185	Target Neighborhood Hits	1460	Shared Neighborhood Hits	82
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

HRX_HUMAN
θ value	6.88961 (rank : 166)	NC score	0.011580 (rank : 295)
Query Neighborhood Hits	185	Target Neighborhood Hits	825	Shared Neighborhood Hits	17
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

LPIN2_HUMAN
θ value	6.88961 (rank : 167)	NC score	0.005340 (rank : 301)
Query Neighborhood Hits	185	Target Neighborhood Hits	117	Shared Neighborhood Hits	3
SwissProt Accessions	Q92539	Gene names	LPIN2, KIAA0249
Domain Architecture	No domain graphic available
Description	Lipin-2.

MYH8_HUMAN
θ value	6.88961 (rank : 168)	NC score	0.066767 (rank : 97)
Query Neighborhood Hits	185	Target Neighborhood Hits	1610	Shared Neighborhood Hits	90
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

OPTN_MOUSE
θ value	6.88961 (rank : 169)	NC score	0.050954 (rank : 218)
Query Neighborhood Hits	185	Target Neighborhood Hits	1120	Shared Neighborhood Hits	75
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

PDZD8_HUMAN
θ value	6.88961 (rank : 170)	NC score	0.110267 (rank : 65)
Query Neighborhood Hits	185	Target Neighborhood Hits	185	Shared Neighborhood Hits	42
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

ZFP13_MOUSE
θ value	6.88961 (rank : 171)	NC score	-0.007098 (rank : 302)
Query Neighborhood Hits	185	Target Neighborhood Hits	771	Shared Neighborhood Hits	3
SwissProt Accessions	P10754, Q80WS0, Q8CDD0	Gene names	Zfp13, Krox-8, Zfp-13
Domain Architecture	No domain graphic available
Description	Zinc finger protein 13 (Zfp-13) (Krox-8 protein).

C102B_HUMAN
θ value	8.99809 (rank : 172)	NC score	0.043577 (rank : 245)
Query Neighborhood Hits	185	Target Neighborhood Hits	542	Shared Neighborhood Hits	58
SwissProt Accessions	Q68D86, Q7Z467, Q8NDK7, Q9H5C1	Gene names	CCDC102B, C18orf14
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 102B.

CTR9_MOUSE
θ value	8.99809 (rank : 173)	NC score	0.017589 (rank : 287)
Query Neighborhood Hits	185	Target Neighborhood Hits	427	Shared Neighborhood Hits	26
SwissProt Accessions	Q62018, Q3UFF5, Q3UY40, Q66JX4, Q7TPS6, Q8BND9, Q8BRD1, Q8C9W7, Q8C9Y3, Q8CHI1	Gene names	Ctr9, Kiaa0155, Sh2bp1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1) (Tetratricopeptide repeat-containing, SH2-binding phosphoprotein of 150 kDa) (TPR-containing, SH2-binding phosphoprotein of 150 kDa) (p150TSP).

KI21A_HUMAN
θ value	8.99809 (rank : 174)	NC score	0.024252 (rank : 281)
Query Neighborhood Hits	185	Target Neighborhood Hits	1543	Shared Neighborhood Hits	80
SwissProt Accessions	Q7Z4S6, Q6UKL9, Q7Z668, Q86WZ5, Q8IVZ8, Q9C0F5, Q9NXU4, Q9Y590	Gene names	KIF21A, KIAA1708, KIF2
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A (Kinesin-like protein KIF2) (NY-REN-62 antigen).

KPCG_HUMAN
θ value	8.99809 (rank : 175)	NC score	0.037455 (rank : 255)
Query Neighborhood Hits	185	Target Neighborhood Hits	1126	Shared Neighborhood Hits	52
SwissProt Accessions	P05129	Gene names	PRKCG, PKCG
Domain Architecture
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

KPCG_MOUSE
θ value	8.99809 (rank : 176)	NC score	0.037476 (rank : 254)
Query Neighborhood Hits	185	Target Neighborhood Hits	1123	Shared Neighborhood Hits	52
SwissProt Accessions	P63318, P05697	Gene names	Prkcg, Pkcc, Pkcg, Prkcc
Domain Architecture	No domain graphic available
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

LCE2A_HUMAN
θ value	8.99809 (rank : 177)	NC score	0.015809 (rank : 291)
Query Neighborhood Hits	185	Target Neighborhood Hits	50	Shared Neighborhood Hits	1
SwissProt Accessions	Q5TA79	Gene names	LCE2A, LEP9
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2A (Late envelope protein 9).

LIPB1_MOUSE
θ value	8.99809 (rank : 178)	NC score	0.036249 (rank : 258)
Query Neighborhood Hits	185	Target Neighborhood Hits	727	Shared Neighborhood Hits	66
SwissProt Accessions	Q8C8U0, Q69ZN5, Q6GQV3, Q80VB4, Q9CUT7	Gene names	Ppfibp1, Kiaa1230
Domain Architecture
Description	Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1).

MRCKA_HUMAN
θ value	8.99809 (rank : 179)	NC score	0.051964 (rank : 197)
Query Neighborhood Hits	185	Target Neighborhood Hits	1999	Shared Neighborhood Hits	115
SwissProt Accessions	Q5VT25, Q59GZ1, Q5H9N9, Q5T797, Q5VT26, Q5VT27, Q86XX2, Q86XX3, Q99646	Gene names	CDC42BPA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42- binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) (DMPK-like alpha).

MYH14_MOUSE
θ value	8.99809 (rank : 180)	NC score	0.059282 (rank : 140)
Query Neighborhood Hits	185	Target Neighborhood Hits	1225	Shared Neighborhood Hits	76
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

MYH9_HUMAN
θ value	8.99809 (rank : 181)	NC score	0.063625 (rank : 110)
Query Neighborhood Hits	185	Target Neighborhood Hits	1762	Shared Neighborhood Hits	88
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

MYH9_MOUSE
θ value	8.99809 (rank : 182)	NC score	0.064366 (rank : 105)
Query Neighborhood Hits	185	Target Neighborhood Hits	1829	Shared Neighborhood Hits	89
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

OXSM_HUMAN
θ value	8.99809 (rank : 183)	NC score	0.007883 (rank : 298)
Query Neighborhood Hits	185	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NWU1	Gene names	OXSM
Domain Architecture	No domain graphic available
Description	3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial precursor (EC 2.3.1.41) (Beta-ketoacyl synthase).

PLEC1_HUMAN
θ value	8.99809 (rank : 184)	NC score	0.035441 (rank : 261)
Query Neighborhood Hits	185	Target Neighborhood Hits	1326	Shared Neighborhood Hits	70
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

TCOF_MOUSE
θ value	8.99809 (rank : 185)	NC score	0.016003 (rank : 290)
Query Neighborhood Hits	185	Target Neighborhood Hits	471	Shared Neighborhood Hits	12
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

ARFG3_HUMAN
θ value	θ > 10 (rank : 186)	NC score	0.050764 (rank : 222)
Query Neighborhood Hits	185	Target Neighborhood Hits	56	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NP61, Q9BSC6, Q9H9J0, Q9NT10, Q9NUP5, Q9Y4V3, Q9Y4V4	Gene names	ARFGAP3, ARFGAP1
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3).

ARFG3_MOUSE
θ value	θ > 10 (rank : 187)	NC score	0.051392 (rank : 211)
Query Neighborhood Hits	185	Target Neighborhood Hits	80	Shared Neighborhood Hits	7
SwissProt Accessions	Q9D8S3, Q99KN8	Gene names	Arfgap3
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3).

ATCAY_HUMAN
θ value	θ > 10 (rank : 188)	NC score	0.051324 (rank : 214)
Query Neighborhood Hits	185	Target Neighborhood Hits	18	Shared Neighborhood Hits	4
SwissProt Accessions	Q86WG3, Q8NAQ2, Q8TAQ3, Q96HC6, Q96JF5	Gene names	ATCAY, KIAA1872
Domain Architecture
Description	Caytaxin (Ataxia Cayman type protein) (BNIP-H).

ATCAY_MOUSE
θ value	θ > 10 (rank : 189)	NC score	0.051752 (rank : 202)
Query Neighborhood Hits	185	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BHE3, Q3TR94	Gene names	Atcay
Domain Architecture
Description	Caytaxin.

BNIP2_HUMAN
θ value	θ > 10 (rank : 190)	NC score	0.054350 (rank : 182)
Query Neighborhood Hits	185	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q12982	Gene names	BNIP2, NIP2
Domain Architecture
Description	BCL2/adenovirus E1B 19 kDa protein-interacting protein 2.

BNIP2_MOUSE
θ value	θ > 10 (rank : 191)	NC score	0.054273 (rank : 184)
Query Neighborhood Hits	185	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	O54940	Gene names	Bnip2, Nip2l
Domain Architecture
Description	BCL2/adenovirus E1B 19 kDa protein-interacting protein 2.

BNIPL_HUMAN
θ value	θ > 10 (rank : 192)	NC score	0.050197 (rank : 231)
Query Neighborhood Hits	185	Target Neighborhood Hits	40	Shared Neighborhood Hits	4
SwissProt Accessions	Q7Z465, Q6DK43, Q8TCY7, Q8WYG2	Gene names	BNIPL
Domain Architecture	No domain graphic available
Description	Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein.

BNIPL_MOUSE
θ value	θ > 10 (rank : 193)	NC score	0.050192 (rank : 232)
Query Neighborhood Hits	185	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q99JU7, Q923E3	Gene names	Bnipl
Domain Architecture	No domain graphic available
Description	Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein.

CCD13_HUMAN
θ value	θ > 10 (rank : 194)	NC score	0.054372 (rank : 181)
Query Neighborhood Hits	185	Target Neighborhood Hits	721	Shared Neighborhood Hits	67
SwissProt Accessions	Q8IYE1	Gene names	CCDC13
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 13.

CCD46_HUMAN
θ value	θ > 10 (rank : 195)	NC score	0.052597 (rank : 193)
Query Neighborhood Hits	185	Target Neighborhood Hits	1430	Shared Neighborhood Hits	85
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

CCD46_MOUSE
θ value	θ > 10 (rank : 196)	NC score	0.051557 (rank : 209)
Query Neighborhood Hits	185	Target Neighborhood Hits	1405	Shared Neighborhood Hits	84
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

CENA1_HUMAN
θ value	θ > 10 (rank : 197)	NC score	0.054456 (rank : 180)
Query Neighborhood Hits	185	Target Neighborhood Hits	87	Shared Neighborhood Hits	7
SwissProt Accessions	O75689	Gene names	CENTA1
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 1 (Putative MAPK-activating protein PM25).

CENA2_HUMAN
θ value	θ > 10 (rank : 198)	NC score	0.057315 (rank : 153)
Query Neighborhood Hits	185	Target Neighborhood Hits	83	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NPF8, Q8N4Q6, Q96SD5	Gene names	CENTA2
Domain Architecture
Description	Centaurin-alpha 2.

CENB1_HUMAN
θ value	θ > 10 (rank : 199)	NC score	0.079192 (rank : 79)
Query Neighborhood Hits	185	Target Neighborhood Hits	383	Shared Neighborhood Hits	14
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

CENB2_HUMAN
θ value	θ > 10 (rank : 200)	NC score	0.087231 (rank : 73)
Query Neighborhood Hits	185	Target Neighborhood Hits	425	Shared Neighborhood Hits	24
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

CENB5_HUMAN
θ value	θ > 10 (rank : 201)	NC score	0.080864 (rank : 76)
Query Neighborhood Hits	185	Target Neighborhood Hits	395	Shared Neighborhood Hits	17
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

CI093_HUMAN
θ value	θ > 10 (rank : 202)	NC score	0.054324 (rank : 183)
Query Neighborhood Hits	185	Target Neighborhood Hits	1088	Shared Neighborhood Hits	78
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

CIP4_HUMAN
θ value	θ > 10 (rank : 203)	NC score	0.069583 (rank : 95)
Query Neighborhood Hits	185	Target Neighborhood Hits	374	Shared Neighborhood Hits	47
SwissProt Accessions	Q15642, O15184, Q5TZN1	Gene names	TRIP10, CIP4
Domain Architecture
Description	Cdc42-interacting protein 4 (Thyroid receptor-interacting protein 10) (TRIP-10).

CK5P2_HUMAN
θ value	θ > 10 (rank : 204)	NC score	0.050489 (rank : 227)
Query Neighborhood Hits	185	Target Neighborhood Hits	1433	Shared Neighborhood Hits	85
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

CN145_HUMAN
θ value	θ > 10 (rank : 205)	NC score	0.051634 (rank : 205)
Query Neighborhood Hits	185	Target Neighborhood Hits	1196	Shared Neighborhood Hits	79
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

CP250_HUMAN
θ value	θ > 10 (rank : 206)	NC score	0.050791 (rank : 221)
Query Neighborhood Hits	185	Target Neighborhood Hits	1805	Shared Neighborhood Hits	85
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

DAPP1_HUMAN
θ value	θ > 10 (rank : 207)	NC score	0.056999 (rank : 159)
Query Neighborhood Hits	185	Target Neighborhood Hits	227	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

DAPP1_MOUSE
θ value	θ > 10 (rank : 208)	NC score	0.058377 (rank : 149)
Query Neighborhood Hits	185	Target Neighborhood Hits	225	Shared Neighborhood Hits	11
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

DDEF1_MOUSE
θ value	θ > 10 (rank : 209)	NC score	0.058586 (rank : 147)
Query Neighborhood Hits	185	Target Neighborhood Hits	592	Shared Neighborhood Hits	24
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

DDEF2_HUMAN
θ value	θ > 10 (rank : 210)	NC score	0.062385 (rank : 117)
Query Neighborhood Hits	185	Target Neighborhood Hits	599	Shared Neighborhood Hits	25
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDEF2_MOUSE
θ value	θ > 10 (rank : 211)	NC score	0.061552 (rank : 126)
Query Neighborhood Hits	185	Target Neighborhood Hits	625	Shared Neighborhood Hits	24
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

DDFL1_HUMAN
θ value	θ > 10 (rank : 212)	NC score	0.055817 (rank : 168)
Query Neighborhood Hits	185	Target Neighborhood Hits	353	Shared Neighborhood Hits	11
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

DDFL1_MOUSE
θ value	θ > 10 (rank : 213)	NC score	0.050470 (rank : 228)
Query Neighborhood Hits	185	Target Neighborhood Hits	324	Shared Neighborhood Hits	11
SwissProt Accessions	Q5U464	Gene names	Ddefl1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1.

DGKD_HUMAN
θ value	θ > 10 (rank : 214)	NC score	0.069751 (rank : 93)
Query Neighborhood Hits	185	Target Neighborhood Hits	231	Shared Neighborhood Hits	50
SwissProt Accessions	Q16760, Q14158, Q6PK55, Q8NG53	Gene names	DGKD, KIAA0145
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase delta (EC 2.7.1.107) (Diglyceride kinase delta) (DGK-delta) (DAG kinase delta) (130 kDa diacylglycerol kinase).

DGKH_HUMAN
θ value	θ > 10 (rank : 215)	NC score	0.078544 (rank : 80)
Query Neighborhood Hits	185	Target Neighborhood Hits	255	Shared Neighborhood Hits	48
SwissProt Accessions	Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9	Gene names	DGKH
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).

DP13A_HUMAN
θ value	θ > 10 (rank : 216)	NC score	0.056402 (rank : 163)
Query Neighborhood Hits	185	Target Neighborhood Hits	107	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UKG1, Q9P2B9	Gene names	APPL1, APPL, DIP13A, KIAA1428
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 alpha (Dip13 alpha) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 1).

DP13A_MOUSE
θ value	θ > 10 (rank : 217)	NC score	0.052905 (rank : 190)
Query Neighborhood Hits	185	Target Neighborhood Hits	96	Shared Neighborhood Hits	16
SwissProt Accessions	Q8K3H0, Q3UJP7, Q69ZJ9, Q8BWZ8, Q8VCJ8, Q9CUW4	Gene names	Appl1, Dip13a, Kiaa1428
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 alpha (Dip13 alpha) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 1).

FA13A_HUMAN
θ value	θ > 10 (rank : 218)	NC score	0.064033 (rank : 107)
Query Neighborhood Hits	185	Target Neighborhood Hits	102	Shared Neighborhood Hits	13
SwissProt Accessions	O94988, Q8NBA3	Gene names	FAM13A1, KIAA0914
Domain Architecture	No domain graphic available
Description	Protein FAM13A1.

FA13A_MOUSE
θ value	θ > 10 (rank : 219)	NC score	0.062929 (rank : 113)
Query Neighborhood Hits	185	Target Neighborhood Hits	83	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BGI4, Q8BZ91	Gene names	Fam13a1, Precm1
Domain Architecture	No domain graphic available
Description	Protein FAM13A1 (Precm1 protein).

GCC2_HUMAN
θ value	θ > 10 (rank : 220)	NC score	0.050502 (rank : 226)
Query Neighborhood Hits	185	Target Neighborhood Hits	1558	Shared Neighborhood Hits	85
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

GOGB1_HUMAN
θ value	θ > 10 (rank : 221)	NC score	0.051565 (rank : 208)
Query Neighborhood Hits	185	Target Neighborhood Hits	2297	Shared Neighborhood Hits	94
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

GRAP_HUMAN
θ value	θ > 10 (rank : 222)	NC score	0.062898 (rank : 114)
Query Neighborhood Hits	185	Target Neighborhood Hits	307	Shared Neighborhood Hits	18
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

GRAP_MOUSE
θ value	θ > 10 (rank : 223)	NC score	0.060244 (rank : 134)
Query Neighborhood Hits	185	Target Neighborhood Hits	309	Shared Neighborhood Hits	18
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

GRB2_HUMAN
θ value	θ > 10 (rank : 224)	NC score	0.058968 (rank : 142)
Query Neighborhood Hits	185	Target Neighborhood Hits	310	Shared Neighborhood Hits	18
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

GRB2_MOUSE
θ value	θ > 10 (rank : 225)	NC score	0.058954 (rank : 143)
Query Neighborhood Hits	185	Target Neighborhood Hits	312	Shared Neighborhood Hits	18
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

HMMR_MOUSE
θ value	θ > 10 (rank : 226)	NC score	0.053815 (rank : 186)
Query Neighborhood Hits	185	Target Neighborhood Hits	1178	Shared Neighborhood Hits	79
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

HOOK3_HUMAN
θ value	θ > 10 (rank : 227)	NC score	0.050822 (rank : 220)
Query Neighborhood Hits	185	Target Neighborhood Hits	1070	Shared Neighborhood Hits	75
SwissProt Accessions	Q86VS8, Q8NBH0, Q9BY13	Gene names	HOOK3
Domain Architecture
Description	Hook homolog 3 (hHK3).

I5P2_HUMAN
θ value	θ > 10 (rank : 228)	NC score	0.278712 (rank : 62)
Query Neighborhood Hits	185	Target Neighborhood Hits	86	Shared Neighborhood Hits	51
SwissProt Accessions	P32019, Q5VSG9, Q5VSH0, Q5VSH1, Q658Q5, Q6P6D4, Q6PD53, Q86YE1	Gene names	INPP5B
Domain Architecture	No domain graphic available
Description	Type II inositol-1,4,5-trisphosphate 5-phosphatase precursor (EC 3.1.3.36) (Phosphoinositide 5-phosphatase) (5PTase) (75 kDa inositol polyphosphate-5-phosphatase).

KMHN1_HUMAN
θ value	θ > 10 (rank : 229)	NC score	0.050560 (rank : 224)
Query Neighborhood Hits	185	Target Neighborhood Hits	950	Shared Neighborhood Hits	73
SwissProt Accessions	Q8TBZ0, Q86YI9, Q8N7W0	Gene names	KMHN1
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1.

MRCKB_MOUSE
θ value	θ > 10 (rank : 230)	NC score	0.053157 (rank : 189)
Query Neighborhood Hits	185	Target Neighborhood Hits	2180	Shared Neighborhood Hits	122
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

MY18B_HUMAN
θ value	θ > 10 (rank : 231)	NC score	0.061467 (rank : 128)
Query Neighborhood Hits	185	Target Neighborhood Hits	1299	Shared Neighborhood Hits	77
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

MYH10_HUMAN
θ value	θ > 10 (rank : 232)	NC score	0.060433 (rank : 131)
Query Neighborhood Hits	185	Target Neighborhood Hits	1620	Shared Neighborhood Hits	82
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH10_MOUSE
θ value	θ > 10 (rank : 233)	NC score	0.060431 (rank : 132)
Query Neighborhood Hits	185	Target Neighborhood Hits	1612	Shared Neighborhood Hits	82
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH11_HUMAN
θ value	θ > 10 (rank : 234)	NC score	0.063824 (rank : 109)
Query Neighborhood Hits	185	Target Neighborhood Hits	1806	Shared Neighborhood Hits	89
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYH11_MOUSE
θ value	θ > 10 (rank : 235)	NC score	0.064512 (rank : 104)
Query Neighborhood Hits	185	Target Neighborhood Hits	1777	Shared Neighborhood Hits	90
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYH13_HUMAN
θ value	θ > 10 (rank : 236)	NC score	0.058476 (rank : 148)
Query Neighborhood Hits	185	Target Neighborhood Hits	1504	Shared Neighborhood Hits	83
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

MYH14_HUMAN
θ value	θ > 10 (rank : 237)	NC score	0.055781 (rank : 169)
Query Neighborhood Hits	185	Target Neighborhood Hits	995	Shared Neighborhood Hits	67
SwissProt Accessions	Q7Z406, Q5CZ75, Q6XYE4, Q76B62, Q8WV23, Q96I22, Q9BT27, Q9BW35, Q9H882	Gene names	MYH14, KIAA2034
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

MYH1_HUMAN
θ value	θ > 10 (rank : 238)	NC score	0.062267 (rank : 119)
Query Neighborhood Hits	185	Target Neighborhood Hits	1478	Shared Neighborhood Hits	84
SwissProt Accessions	P12882, Q9Y622	Gene names	MYH1
Domain Architecture
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1) (Myosin heavy chain IIx/d) (MyHC-IIx/d).

MYH1_MOUSE
θ value	θ > 10 (rank : 239)	NC score	0.061899 (rank : 121)
Query Neighborhood Hits	185	Target Neighborhood Hits	1461	Shared Neighborhood Hits	85
SwissProt Accessions	Q5SX40	Gene names	Myh1
Domain Architecture	No domain graphic available
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1).

MYH2_HUMAN
θ value	θ > 10 (rank : 240)	NC score	0.061753 (rank : 123)
Query Neighborhood Hits	185	Target Neighborhood Hits	1491	Shared Neighborhood Hits	84
SwissProt Accessions	Q9UKX2, Q14322, Q16229	Gene names	MYH2, MYHSA2
Domain Architecture
Description	Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa).

MYH4_HUMAN
θ value	θ > 10 (rank : 241)	NC score	0.063358 (rank : 112)
Query Neighborhood Hits	185	Target Neighborhood Hits	1377	Shared Neighborhood Hits	83
SwissProt Accessions	Q9Y623	Gene names	MYH4
Domain Architecture
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal) (Myosin heavy chain IIb) (MyHC-IIb).

MYH4_MOUSE
θ value	θ > 10 (rank : 242)	NC score	0.060810 (rank : 129)
Query Neighborhood Hits	185	Target Neighborhood Hits	1476	Shared Neighborhood Hits	84
SwissProt Accessions	Q5SX39	Gene names	Myh4
Domain Architecture	No domain graphic available
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal).

MYH6_HUMAN
θ value	θ > 10 (rank : 243)	NC score	0.059445 (rank : 139)
Query Neighborhood Hits	185	Target Neighborhood Hits	1426	Shared Neighborhood Hits	79
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

MYH6_MOUSE
θ value	θ > 10 (rank : 244)	NC score	0.060292 (rank : 133)
Query Neighborhood Hits	185	Target Neighborhood Hits	1501	Shared Neighborhood Hits	78
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

MYH7_HUMAN
θ value	θ > 10 (rank : 245)	NC score	0.057118 (rank : 156)
Query Neighborhood Hits	185	Target Neighborhood Hits	1559	Shared Neighborhood Hits	83
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

MYH8_MOUSE
θ value	θ > 10 (rank : 246)	NC score	0.063933 (rank : 108)
Query Neighborhood Hits	185	Target Neighborhood Hits	1600	Shared Neighborhood Hits	84
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

MYO10_HUMAN
θ value	θ > 10 (rank : 247)	NC score	0.075807 (rank : 84)
Query Neighborhood Hits	185	Target Neighborhood Hits	920	Shared Neighborhood Hits	74
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

MYO15_HUMAN
θ value	θ > 10 (rank : 248)	NC score	0.055169 (rank : 175)
Query Neighborhood Hits	185	Target Neighborhood Hits	671	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

MYO15_MOUSE
θ value	θ > 10 (rank : 249)	NC score	0.055618 (rank : 173)
Query Neighborhood Hits	185	Target Neighborhood Hits	467	Shared Neighborhood Hits	22
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

MYO1E_HUMAN
θ value	θ > 10 (rank : 250)	NC score	0.058156 (rank : 151)
Query Neighborhood Hits	185	Target Neighborhood Hits	293	Shared Neighborhood Hits	24
SwissProt Accessions	Q12965, Q14778	Gene names	MYO1E, MYO1C
Domain Architecture
Description	Myosin Ie (Myosin Ic).

MYO1F_HUMAN
θ value	θ > 10 (rank : 251)	NC score	0.059988 (rank : 136)
Query Neighborhood Hits	185	Target Neighborhood Hits	275	Shared Neighborhood Hits	23
SwissProt Accessions	O00160, Q8WWN7	Gene names	MYO1F
Domain Architecture
Description	Myosin If (Myosin-IE).

MYO1F_MOUSE
θ value	θ > 10 (rank : 252)	NC score	0.059872 (rank : 137)
Query Neighborhood Hits	185	Target Neighborhood Hits	262	Shared Neighborhood Hits	22
SwissProt Accessions	P70248	Gene names	Myo1f
Domain Architecture
Description	Myosin If.

MYO5A_HUMAN
θ value	θ > 10 (rank : 253)	NC score	0.061608 (rank : 125)
Query Neighborhood Hits	185	Target Neighborhood Hits	1092	Shared Neighborhood Hits	76
SwissProt Accessions	Q9Y4I1, O60653, Q07902, Q16249, Q9UE30, Q9UE31	Gene names	MYO5A, MYH12
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle) (Myosin heavy chain 12) (Myoxin).

MYO5A_MOUSE
θ value	θ > 10 (rank : 254)	NC score	0.062368 (rank : 118)
Query Neighborhood Hits	185	Target Neighborhood Hits	1117	Shared Neighborhood Hits	74
SwissProt Accessions	Q99104	Gene names	Myo5a, Dilute
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle).

MYO5B_HUMAN
θ value	θ > 10 (rank : 255)	NC score	0.061548 (rank : 127)
Query Neighborhood Hits	185	Target Neighborhood Hits	911	Shared Neighborhood Hits	68
SwissProt Accessions	Q9ULV0	Gene names	MYO5B, KIAA1119
Domain Architecture
Description	Myosin-5B (Myosin Vb).

MYO5C_HUMAN
θ value	θ > 10 (rank : 256)	NC score	0.064930 (rank : 102)
Query Neighborhood Hits	185	Target Neighborhood Hits	1206	Shared Neighborhood Hits	79
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

MYO6_HUMAN
θ value	θ > 10 (rank : 257)	NC score	0.057067 (rank : 158)
Query Neighborhood Hits	185	Target Neighborhood Hits	727	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UM54, Q9BZZ7, Q9UEG2	Gene names	MYO6, KIAA0389
Domain Architecture
Description	Myosin-6 (Myosin VI).

MYO6_MOUSE
θ value	θ > 10 (rank : 258)	NC score	0.055073 (rank : 177)
Query Neighborhood Hits	185	Target Neighborhood Hits	586	Shared Neighborhood Hits	53
SwissProt Accessions	Q64331	Gene names	Myo6, Sv
Domain Architecture
Description	Myosin-6 (Myosin VI).

MYO7A_HUMAN
θ value	θ > 10 (rank : 259)	NC score	0.055779 (rank : 170)
Query Neighborhood Hits	185	Target Neighborhood Hits	209	Shared Neighborhood Hits	25
SwissProt Accessions	Q13402, P78427, Q13321, Q14785, Q92821, Q92822	Gene names	MYO7A, USH1B
Domain Architecture
Description	Myosin-7A (Myosin VIIa).

MYO7A_MOUSE
θ value	θ > 10 (rank : 260)	NC score	0.057312 (rank : 154)
Query Neighborhood Hits	185	Target Neighborhood Hits	235	Shared Neighborhood Hits	26
SwissProt Accessions	P97479	Gene names	Myo7a, Myo7
Domain Architecture
Description	Myosin-7A (Myosin VIIa).

NCK2_HUMAN
θ value	θ > 10 (rank : 261)	NC score	0.066284 (rank : 98)
Query Neighborhood Hits	185	Target Neighborhood Hits	310	Shared Neighborhood Hits	20
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

NIN_HUMAN
θ value	θ > 10 (rank : 262)	NC score	0.051568 (rank : 207)
Query Neighborhood Hits	185	Target Neighborhood Hits	1416	Shared Neighborhood Hits	83
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

P55G_HUMAN
θ value	θ > 10 (rank : 263)	NC score	0.069972 (rank : 92)
Query Neighborhood Hits	185	Target Neighborhood Hits	451	Shared Neighborhood Hits	48
SwissProt Accessions	Q92569, O60482	Gene names	PIK3R3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

P55G_MOUSE
θ value	θ > 10 (rank : 264)	NC score	0.065274 (rank : 100)
Query Neighborhood Hits	185	Target Neighborhood Hits	401	Shared Neighborhood Hits	41
SwissProt Accessions	Q64143	Gene names	Pik3r3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

P85B_HUMAN
θ value	θ > 10 (rank : 265)	NC score	0.130542 (rank : 64)
Query Neighborhood Hits	185	Target Neighborhood Hits	543	Shared Neighborhood Hits	70
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

P85B_MOUSE
θ value	θ > 10 (rank : 266)	NC score	0.091907 (rank : 70)
Query Neighborhood Hits	185	Target Neighborhood Hits	519	Shared Neighborhood Hits	65
SwissProt Accessions	O08908	Gene names	Pik3r2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

PIBF1_HUMAN
θ value	θ > 10 (rank : 267)	NC score	0.051940 (rank : 200)
Query Neighborhood Hits	185	Target Neighborhood Hits	1041	Shared Neighborhood Hits	76
SwissProt Accessions	Q8WXW3, O95664, Q6U9V2, Q6UG50, Q86V07, Q96SF4	Gene names	PIBF1, C13orf24, PIBF
Domain Architecture
Description	Progesterone-induced-blocking factor 1.

PKHA1_HUMAN
θ value	θ > 10 (rank : 268)	NC score	0.062124 (rank : 120)
Query Neighborhood Hits	185	Target Neighborhood Hits	127	Shared Neighborhood Hits	17
SwissProt Accessions	Q9HB21, Q9BVK0	Gene names	PLEKHA1, TAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

PKHA1_MOUSE
θ value	θ > 10 (rank : 269)	NC score	0.056797 (rank : 160)
Query Neighborhood Hits	185	Target Neighborhood Hits	120	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BUL6, Q8BK96, Q8BXU1, Q8VE13	Gene names	Plekha1, Tapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

RAD50_HUMAN
θ value	θ > 10 (rank : 270)	NC score	0.051116 (rank : 215)
Query Neighborhood Hits	185	Target Neighborhood Hits	1317	Shared Neighborhood Hits	79
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

RAD50_MOUSE
θ value	θ > 10 (rank : 271)	NC score	0.051464 (rank : 210)
Query Neighborhood Hits	185	Target Neighborhood Hits	1366	Shared Neighborhood Hits	82
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

RASF1_HUMAN
θ value	θ > 10 (rank : 272)	NC score	0.080618 (rank : 77)
Query Neighborhood Hits	185	Target Neighborhood Hits	62	Shared Neighborhood Hits	31
SwissProt Accessions	Q9NS23, O14571, O60539, O60710, Q9HB04, Q9HB18, Q9NS22, Q9UND4, Q9UND5	Gene names	RASSF1, RDA32
Domain Architecture	No domain graphic available
Description	Ras association domain-containing protein 1.

RASF1_MOUSE
θ value	θ > 10 (rank : 273)	NC score	0.095181 (rank : 67)
Query Neighborhood Hits	185	Target Neighborhood Hits	74	Shared Neighborhood Hits	35
SwissProt Accessions	Q99MK9, Q9WUF5	Gene names	Rassf1
Domain Architecture	No domain graphic available
Description	Ras association domain-containing protein 1 (Protein 123F2).

RBP24_HUMAN
θ value	θ > 10 (rank : 274)	NC score	0.050291 (rank : 230)
Query Neighborhood Hits	185	Target Neighborhood Hits	1559	Shared Neighborhood Hits	85
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

REST_MOUSE
θ value	θ > 10 (rank : 275)	NC score	0.052837 (rank : 191)
Query Neighborhood Hits	185	Target Neighborhood Hits	1506	Shared Neighborhood Hits	84
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

SH3K1_MOUSE
θ value	θ > 10 (rank : 276)	NC score	0.051739 (rank : 203)
Query Neighborhood Hits	185	Target Neighborhood Hits	332	Shared Neighborhood Hits	25
SwissProt Accessions	Q8R550, Q8CAL8, Q8CEF6, Q8R545, Q8R546, Q8R547, Q8R548, Q8R549, Q8R551, Q9CTQ9, Q9DC14, Q9JKC3	Gene names	Sh3kbp1, Ruk, Seta
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (SH3-containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk).

SMAP1_HUMAN
θ value	θ > 10 (rank : 277)	NC score	0.055136 (rank : 176)
Query Neighborhood Hits	185	Target Neighborhood Hits	98	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IYB5, Q53H70, Q5SYQ2, Q6PK24, Q8NDH4, Q96L38, Q96L39, Q9H8X4	Gene names	SMAP1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

SMAP1_MOUSE
θ value	θ > 10 (rank : 278)	NC score	0.054938 (rank : 178)
Query Neighborhood Hits	185	Target Neighborhood Hits	120	Shared Neighborhood Hits	8
SwissProt Accessions	Q91VZ6, Q497I6, Q68EF3	Gene names	Smap1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

SMP1L_HUMAN
θ value	θ > 10 (rank : 279)	NC score	0.056677 (rank : 162)
Query Neighborhood Hits	185	Target Neighborhood Hits	74	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WU79, Q5QPL2, Q96C93, Q9NST2, Q9UJL8	Gene names	SMAP1L
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like.

SMP1L_MOUSE
θ value	θ > 10 (rank : 280)	NC score	0.056377 (rank : 164)
Query Neighborhood Hits	185	Target Neighborhood Hits	70	Shared Neighborhood Hits	5
SwissProt Accessions	Q7TN29, Q3U798	Gene names	Smap1l, Smap2
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like (Stromal membrane- associated protein 2).

SRBS1_HUMAN
θ value	θ > 10 (rank : 281)	NC score	0.051067 (rank : 216)
Query Neighborhood Hits	185	Target Neighborhood Hits	396	Shared Neighborhood Hits	24
SwissProt Accessions	Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338	Gene names	SORBS1, KIAA1296, SH3D5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

SRBS1_MOUSE
θ value	θ > 10 (rank : 282)	NC score	0.050522 (rank : 225)
Query Neighborhood Hits	185	Target Neighborhood Hits	409	Shared Neighborhood Hits	25
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

STAC3_HUMAN
θ value	θ > 10 (rank : 283)	NC score	0.087013 (rank : 74)
Query Neighborhood Hits	185	Target Neighborhood Hits	228	Shared Neighborhood Hits	51
SwissProt Accessions	Q96MF2, Q96HU5	Gene names	STAC3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

STAC3_MOUSE
θ value	θ > 10 (rank : 284)	NC score	0.088762 (rank : 72)
Query Neighborhood Hits	185	Target Neighborhood Hits	232	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BZ71	Gene names	Stac3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

STAC_HUMAN
θ value	θ > 10 (rank : 285)	NC score	0.070135 (rank : 91)
Query Neighborhood Hits	185	Target Neighborhood Hits	276	Shared Neighborhood Hits	49
SwissProt Accessions	Q99469	Gene names	STAC
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

STAC_MOUSE
θ value	θ > 10 (rank : 286)	NC score	0.076926 (rank : 83)
Query Neighborhood Hits	185	Target Neighborhood Hits	268	Shared Neighborhood Hits	48
SwissProt Accessions	P97306	Gene names	Stac
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

SYCP1_MOUSE
θ value	θ > 10 (rank : 287)	NC score	0.050304 (rank : 229)
Query Neighborhood Hits	185	Target Neighborhood Hits	1456	Shared Neighborhood Hits	80
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

TCRG1_HUMAN
θ value	θ > 10 (rank : 288)	NC score	0.056719 (rank : 161)
Query Neighborhood Hits	185	Target Neighborhood Hits	929	Shared Neighborhood Hits	64
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

TCRG1_MOUSE
θ value	θ > 10 (rank : 289)	NC score	0.057073 (rank : 157)
Query Neighborhood Hits	185	Target Neighborhood Hits	947	Shared Neighborhood Hits	65
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

TPM4_HUMAN
θ value	θ > 10 (rank : 290)	NC score	0.052585 (rank : 194)
Query Neighborhood Hits	185	Target Neighborhood Hits	525	Shared Neighborhood Hits	57
SwissProt Accessions	P67936, P07226, Q15659, Q9BU85, Q9H8Q3	Gene names	TPM4
Domain Architecture	No domain graphic available
Description	Tropomyosin alpha-4 chain (Tropomyosin-4) (TM30p1).

TPM4_MOUSE
θ value	θ > 10 (rank : 291)	NC score	0.052222 (rank : 196)
Query Neighborhood Hits	185	Target Neighborhood Hits	703	Shared Neighborhood Hits	62
SwissProt Accessions	Q6IRU2	Gene names	Tpm4
Domain Architecture	No domain graphic available
Description	Tropomyosin alpha-4 chain (Tropomyosin-4).

UN13A_HUMAN
θ value	θ > 10 (rank : 292)	NC score	0.092461 (rank : 69)
Query Neighborhood Hits	185	Target Neighborhood Hits	285	Shared Neighborhood Hits	52
SwissProt Accessions	Q9UPW8	Gene names	UNC13A, KIAA1032
Domain Architecture	No domain graphic available
Description	Unc-13 homolog A (Munc13-1).

UN13B_HUMAN
θ value	θ > 10 (rank : 293)	NC score	0.091587 (rank : 71)
Query Neighborhood Hits	185	Target Neighborhood Hits	217	Shared Neighborhood Hits	51
SwissProt Accessions	O14795	Gene names	UNC13B, UNC13
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

UN13B_MOUSE
θ value	θ > 10 (rank : 294)	NC score	0.085117 (rank : 75)
Query Neighborhood Hits	185	Target Neighborhood Hits	210	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Z1N9	Gene names	Unc13b, Unc13a
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

VAV2_HUMAN
θ value	θ > 10 (rank : 295)	NC score	0.066222 (rank : 99)
Query Neighborhood Hits	185	Target Neighborhood Hits	453	Shared Neighborhood Hits	55
SwissProt Accessions	P52735	Gene names	VAV2
Domain Architecture
Description	Protein vav-2.

VAV2_MOUSE
θ value	θ > 10 (rank : 296)	NC score	0.065040 (rank : 101)
Query Neighborhood Hits	185	Target Neighborhood Hits	456	Shared Neighborhood Hits	49
SwissProt Accessions	Q60992	Gene names	Vav2
Domain Architecture
Description	Protein vav-2.

VAV3_HUMAN
θ value	θ > 10 (rank : 297)	NC score	0.073608 (rank : 86)
Query Neighborhood Hits	185	Target Neighborhood Hits	398	Shared Neighborhood Hits	48
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

VAV3_MOUSE
θ value	θ > 10 (rank : 298)	NC score	0.072975 (rank : 88)
Query Neighborhood Hits	185	Target Neighborhood Hits	404	Shared Neighborhood Hits	50
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

VAV_HUMAN
θ value	θ > 10 (rank : 299)	NC score	0.055652 (rank : 172)
Query Neighborhood Hits	185	Target Neighborhood Hits	452	Shared Neighborhood Hits	53
SwissProt Accessions	P15498, Q15860	Gene names	VAV1, VAV
Domain Architecture
Description	Proto-oncogene vav.

VAV_MOUSE
θ value	θ > 10 (rank : 300)	NC score	0.057398 (rank : 152)
Query Neighborhood Hits	185	Target Neighborhood Hits	430	Shared Neighborhood Hits	48
SwissProt Accessions	P27870, Q8BTV7	Gene names	Vav1, Vav
Domain Architecture
Description	Proto-oncogene vav (p95vav).

VINEX_HUMAN
θ value	θ > 10 (rank : 301)	NC score	0.051943 (rank : 199)
Query Neighborhood Hits	185	Target Neighborhood Hits	270	Shared Neighborhood Hits	20
SwissProt Accessions	O60504, Q9UQE4	Gene names	SORBS3, SCAM1
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1).

VINEX_MOUSE
θ value	θ > 10 (rank : 302)	NC score	0.054773 (rank : 179)
Query Neighborhood Hits	185	Target Neighborhood Hits	286	Shared Neighborhood Hits	20
SwissProt Accessions	Q9R1Z8, Q62423	Gene names	Sorbs3, Scam1, Sh3d4
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1) (SH3 domain-containing protein SH3P3).

Hits sorted by NC score

RGAP1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	185	Target Neighborhood Hits	185	Shared Neighborhood Hits	185
SwissProt Accessions	Q9WVM1, Q3THR5, Q3TI41, Q3TM81	Gene names	Racgap1, Mgcracgap
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

RGAP1_HUMAN
NC score	0.981980 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	185	Target Neighborhood Hits	189	Shared Neighborhood Hits	126
SwissProt Accessions	Q9H0H5, Q6PJ26, Q9NWN2, Q9P250, Q9P2W2	Gene names	RACGAP1, KIAA1478, MGCRACGAP
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

CHIO_MOUSE
NC score	0.818720 (rank : 3)	θ value	3.28125e-26 (rank : 5)
Query Neighborhood Hits	185	Target Neighborhood Hits	130	Shared Neighborhood Hits	94
SwissProt Accessions	Q80XD1, Q9D9W2, Q9ER57	Gene names	Chn2, Arhgap3, Bch
Domain Architecture	No domain graphic available
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

RHG09_HUMAN
NC score	0.811033 (rank : 4)	θ value	9.26847e-13 (rank : 28)
Query Neighborhood Hits	185	Target Neighborhood Hits	186	Shared Neighborhood Hits	67
SwissProt Accessions	Q9BRR9, Q8TCJ3, Q8WYR0, Q96EZ2, Q96S74	Gene names	ARHGAP9
Domain Architecture
Description	Rho-GTPase-activating protein 9.

GMIP_MOUSE
NC score	0.803061 (rank : 5)	θ value	2.60593e-15 (rank : 22)
Query Neighborhood Hits	185	Target Neighborhood Hits	202	Shared Neighborhood Hits	90
SwissProt Accessions	Q6PGG2, Q6P9S3	Gene names	Gmip
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

GMIP_HUMAN
NC score	0.800940 (rank : 6)	θ value	4.02038e-16 (rank : 19)
Query Neighborhood Hits	185	Target Neighborhood Hits	225	Shared Neighborhood Hits	87
SwissProt Accessions	Q9P107	Gene names	GMIP
Domain Architecture	No domain graphic available
Description	GEM-interacting protein (GMIP).

CHIN_MOUSE
NC score	0.793956 (rank : 7)	θ value	1.85889e-29 (rank : 3)
Query Neighborhood Hits	185	Target Neighborhood Hits	229	Shared Neighborhood Hits	95
SwissProt Accessions	Q91V57, Q3UGY3, Q7TQE5, Q8BWU6, Q9D9B3	Gene names	Chn1, Arhgap2
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

CHIN_HUMAN
NC score	0.790710 (rank : 8)	θ value	7.06379e-29 (rank : 4)
Query Neighborhood Hits	185	Target Neighborhood Hits	227	Shared Neighborhood Hits	94
SwissProt Accessions	P15882, Q53SD6, Q53SH5, Q96FB0	Gene names	CHN1, ARHGAP2, CHN
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

CHIO_HUMAN
NC score	0.786580 (rank : 9)	θ value	9.54697e-26 (rank : 6)
Query Neighborhood Hits	185	Target Neighborhood Hits	220	Shared Neighborhood Hits	94
SwissProt Accessions	P52757, Q75MM2	Gene names	CHN2, ARHGAP3, BCH
Domain Architecture
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

RHG12_HUMAN
NC score	0.785558 (rank : 10)	θ value	1.80466e-16 (rank : 15)
Query Neighborhood Hits	185	Target Neighborhood Hits	190	Shared Neighborhood Hits	64
SwissProt Accessions	Q8IWW6, Q86UB3, Q8IWW7, Q8N3L1, Q9NT76	Gene names	ARHGAP12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

RHG12_MOUSE
NC score	0.781264 (rank : 11)	θ value	3.07829e-16 (rank : 18)
Query Neighborhood Hits	185	Target Neighborhood Hits	204	Shared Neighborhood Hits	62
SwissProt Accessions	Q8C0D4, Q8BVP8	Gene names	Arhgap12
Domain Architecture
Description	Rho-GTPase-activating protein 12.

OPHN1_HUMAN
NC score	0.770944 (rank : 12)	θ value	2.13179e-17 (rank : 11)
Query Neighborhood Hits	185	Target Neighborhood Hits	161	Shared Neighborhood Hits	70
SwissProt Accessions	O60890, Q5JQ81, Q8WX47	Gene names	OPHN1
Domain Architecture
Description	Oligophrenin 1.

RHG06_HUMAN
NC score	0.768998 (rank : 13)	θ value	2.69671e-12 (rank : 34)
Query Neighborhood Hits	185	Target Neighborhood Hits	114	Shared Neighborhood Hits	62
SwissProt Accessions	O43182, O43437, Q9P1B3, Q9UK81, Q9UK82	Gene names	ARHGAP6, RHOGAP6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

RHG06_MOUSE
NC score	0.768111 (rank : 14)	θ value	2.0648e-12 (rank : 32)
Query Neighborhood Hits	185	Target Neighborhood Hits	105	Shared Neighborhood Hits	62
SwissProt Accessions	O54834, Q9QZL8	Gene names	Arhgap6
Domain Architecture
Description	Rho-GTPase-activating protein 6 (Rho-type GTPase-activating protein RhoGAPX-1).

OPHN1_MOUSE
NC score	0.767090 (rank : 15)	θ value	3.63628e-17 (rank : 12)
Query Neighborhood Hits	185	Target Neighborhood Hits	174	Shared Neighborhood Hits	68
SwissProt Accessions	Q99J31, Q544K7	Gene names	Ophn1
Domain Architecture
Description	Oligophrenin 1.

GRLF1_HUMAN
NC score	0.762676 (rank : 16)	θ value	2.43908e-13 (rank : 27)
Query Neighborhood Hits	185	Target Neighborhood Hits	167	Shared Neighborhood Hits	62
SwissProt Accessions	Q9NRY4, Q14452, Q9C0E1	Gene names	GRLF1, GRF1, KIAA1722
Domain Architecture
Description	Glucocorticoid receptor DNA-binding factor 1 (Glucocorticoid receptor repression factor 1) (GRF-1) (Rho GAP p190A) (p190-A).

3BP1_MOUSE
NC score	0.758512 (rank : 17)	θ value	2.79066e-09 (rank : 45)
Query Neighborhood Hits	185	Target Neighborhood Hits	238	Shared Neighborhood Hits	64
SwissProt Accessions	P55194, Q99KK8	Gene names	Sh3bp1, 3bp1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

TCGAP_MOUSE
NC score	0.754107 (rank : 18)	θ value	2.35696e-16 (rank : 17)
Query Neighborhood Hits	185	Target Neighborhood Hits	409	Shared Neighborhood Hits	67
SwissProt Accessions	Q80YF9, Q6P7W6	Gene names	Snx26, Tcgap
Domain Architecture	No domain graphic available
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

3BP1_HUMAN
NC score	0.751045 (rank : 19)	θ value	1.58096e-12 (rank : 30)
Query Neighborhood Hits	185	Target Neighborhood Hits	376	Shared Neighborhood Hits	69
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

RHG18_HUMAN
NC score	0.750594 (rank : 20)	θ value	4.30538e-10 (rank : 43)
Query Neighborhood Hits	185	Target Neighborhood Hits	90	Shared Neighborhood Hits	61
SwissProt Accessions	Q8N392, Q58EZ3, Q6P679, Q6PJD7, Q96S64	Gene names	ARHGAP18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18 (MacGAP).

RHG01_HUMAN
NC score	0.748407 (rank : 21)	θ value	1.2105e-12 (rank : 29)
Query Neighborhood Hits	185	Target Neighborhood Hits	75	Shared Neighborhood Hits	61
SwissProt Accessions	Q07960	Gene names	ARHGAP1, CDC42GAP, RHOGAP1
Domain Architecture
Description	Rho-GTPase-activating protein 1 (GTPase-activating protein rhoOGAP) (Rho-related small GTPase protein activator) (CDC42 GTPase-activating protein) (p50-RhoGAP).

RHG05_MOUSE
NC score	0.741957 (rank : 22)	θ value	4.91457e-14 (rank : 25)
Query Neighborhood Hits	185	Target Neighborhood Hits	165	Shared Neighborhood Hits	69
SwissProt Accessions	P97393	Gene names	Arhgap5, Rhogap5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

RHG18_MOUSE
NC score	0.740276 (rank : 23)	θ value	3.29651e-10 (rank : 42)
Query Neighborhood Hits	185	Target Neighborhood Hits	110	Shared Neighborhood Hits	64
SwissProt Accessions	Q8K0Q5, Q8BP03, Q8R196	Gene names	Arhgap18
Domain Architecture	No domain graphic available
Description	Rho-GTPase-activating protein 18.

RHG26_HUMAN
NC score	0.738101 (rank : 24)	θ value	7.82807e-20 (rank : 10)
Query Neighborhood Hits	185	Target Neighborhood Hits	281	Shared Neighborhood Hits	72
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

RHG05_HUMAN
NC score	0.736999 (rank : 25)	θ value	1.68911e-14 (rank : 23)
Query Neighborhood Hits	185	Target Neighborhood Hits	158	Shared Neighborhood Hits	66
SwissProt Accessions	Q13017	Gene names	ARHGAP5, RHOGAP5
Domain Architecture
Description	Rho-GTPase-activating protein 5 (p190-B).

RHG08_MOUSE
NC score	0.735788 (rank : 26)	θ value	2.69671e-12 (rank : 36)
Query Neighborhood Hits	185	Target Neighborhood Hits	73	Shared Neighborhood Hits	61
SwissProt Accessions	Q9CXP4, Q99JY7	Gene names	Arhgap8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

RBP1_MOUSE
NC score	0.734601 (rank : 27)	θ value	3.63628e-17 (rank : 13)
Query Neighborhood Hits	185	Target Neighborhood Hits	493	Shared Neighborhood Hits	107
SwissProt Accessions	Q62172, Q9CRE5	Gene names	Ralbp1, Rip1
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

ABR_HUMAN
NC score	0.733942 (rank : 28)	θ value	1.09232e-21 (rank : 9)
Query Neighborhood Hits	185	Target Neighborhood Hits	166	Shared Neighborhood Hits	69
SwissProt Accessions	Q12979, Q13693, Q13694	Gene names	ABR
Domain Architecture
Description	Active breakpoint cluster region-related protein.

RHG08_HUMAN
NC score	0.731592 (rank : 29)	θ value	2.69671e-12 (rank : 35)
Query Neighborhood Hits	185	Target Neighborhood Hits	88	Shared Neighborhood Hits	61
SwissProt Accessions	Q9NSG0, O75983, O95695, Q96RW1, Q96RW2, Q9HA49, Q9HC46, Q9NVX8, Q9NXL1, Q9UH20	Gene names	ARHGAP8
Domain Architecture
Description	Rho-GTPase-activating protein 8.

RBP1_HUMAN
NC score	0.717782 (rank : 30)	θ value	6.85773e-16 (rank : 21)
Query Neighborhood Hits	185	Target Neighborhood Hits	521	Shared Neighborhood Hits	108
SwissProt Accessions	Q15311	Gene names	RALBP1, RLIP1, RLIP76
Domain Architecture
Description	RalA-binding protein 1 (RalBP1) (Ral-interacting protein 1) (76 kDa Ral-interacting protein) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase).

BCR_HUMAN
NC score	0.717550 (rank : 31)	θ value	1.80466e-16 (rank : 14)
Query Neighborhood Hits	185	Target Neighborhood Hits	204	Shared Neighborhood Hits	68
SwissProt Accessions	P11274, P78501, Q12842	Gene names	BCR, BCR1
Domain Architecture
Description	Breakpoint cluster region protein (EC 2.7.11.1) (NY-REN-26 antigen).

RHG25_MOUSE
NC score	0.713883 (rank : 32)	θ value	3.76295e-14 (rank : 24)
Query Neighborhood Hits	185	Target Neighborhood Hits	492	Shared Neighborhood Hits	88
SwissProt Accessions	Q8BYW1, Q2VPR2, Q3TE04, Q3TVX0, Q3UVB7, Q6A0E0, Q8BX98	Gene names	Arhgap25, Kiaa0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RHG25_HUMAN
NC score	0.696405 (rank : 33)	θ value	4.91457e-14 (rank : 26)
Query Neighborhood Hits	185	Target Neighborhood Hits	550	Shared Neighborhood Hits	101
SwissProt Accessions	P42331, Q8IXQ2	Gene names	ARHGAP25, KIAA0053
Domain Architecture
Description	Rho-GTPase-activating protein 25.

RHG04_HUMAN
NC score	0.681466 (rank : 34)	θ value	1.47974e-10 (rank : 41)
Query Neighborhood Hits	185	Target Neighborhood Hits	307	Shared Neighborhood Hits	73
SwissProt Accessions	P98171, Q14144	Gene names	ARHGAP4, KIAA0131, RGC1, RHOGAP4
Domain Architecture
Description	Rho-GTPase-activating protein 4 (Rho-GAP hematopoietic protein C1) (p115).

SRGP2_HUMAN
NC score	0.672533 (rank : 35)	θ value	1.58096e-12 (rank : 31)
Query Neighborhood Hits	185	Target Neighborhood Hits	331	Shared Neighborhood Hits	81
SwissProt Accessions	O43295, Q8IX13, Q8IZV8	Gene names	SRGAP3, ARHGAP14, KIAA0411, MEGAP, SRGAP2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Mental disorder- associated GAP) (Rho-GTPase-activating protein 14).

TAGAP_MOUSE
NC score	0.672007 (rank : 36)	θ value	6.43352e-06 (rank : 57)
Query Neighborhood Hits	185	Target Neighborhood Hits	83	Shared Neighborhood Hits	59
SwissProt Accessions	Q8K2L9, Q920D6	Gene names	Tagap, Tagap1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

TCGAP_HUMAN
NC score	0.668923 (rank : 37)	θ value	2.35696e-16 (rank : 16)
Query Neighborhood Hits	185	Target Neighborhood Hits	872	Shared Neighborhood Hits	67
SwissProt Accessions	O14559, O14552, O14560, Q6ZSP6, Q96CP3, Q9NT23	Gene names	SNX26, TCGAP
Domain Architecture
Description	TC10/CDC42 GTPase-activating protein (Sorting nexin-26).

TAGAP_HUMAN
NC score	0.668909 (rank : 38)	θ value	1.17247e-07 (rank : 50)
Query Neighborhood Hits	185	Target Neighborhood Hits	82	Shared Neighborhood Hits	60
SwissProt Accessions	Q8N103, Q2NKM8, Q8NI40, Q96KZ2, Q96QA2	Gene names	TAGAP, TAGAP1
Domain Architecture	No domain graphic available
Description	T-cell activation Rho GTPase-activating protein (T-cell activation GTPase-activating protein).

SRGP2_MOUSE
NC score	0.664682 (rank : 39)	θ value	6.00763e-12 (rank : 37)
Query Neighborhood Hits	185	Target Neighborhood Hits	324	Shared Neighborhood Hits	81
SwissProt Accessions	Q812A2, Q80U09, Q8BKP4, Q8BLD0, Q925I2	Gene names	Srgap3, Arhgap14, Kiaa0411, Srgap2
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 3 (srGAP3) (srGAP2) (WAVE- associated Rac GTPase-activating protein) (WRP) (Rho-GTPase-activating protein 14).

SRGP1_HUMAN
NC score	0.658841 (rank : 40)	θ value	1.133e-10 (rank : 40)
Query Neighborhood Hits	185	Target Neighborhood Hits	390	Shared Neighborhood Hits	86
SwissProt Accessions	Q7Z6B7, Q9H8A3, Q9P2P2	Gene names	SRGAP1, ARHGAP13, KIAA1304
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 1 (srGAP1) (Rho-GTPase- activating protein 13).

FNBP2_HUMAN
NC score	0.651493 (rank : 41)	θ value	6.21693e-09 (rank : 46)
Query Neighborhood Hits	185	Target Neighborhood Hits	432	Shared Neighborhood Hits	91
SwissProt Accessions	O75044	Gene names	SRGAP2, FNBP2, KIAA0456
Domain Architecture
Description	SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2).

CEND2_HUMAN
NC score	0.634497 (rank : 42)	θ value	5.25075e-16 (rank : 20)
Query Neighborhood Hits	185	Target Neighborhood Hits	166	Shared Neighborhood Hits	59
SwissProt Accessions	Q96P48, O94879, Q59FI7, Q6PHS3, Q8WU51, Q96HP6, Q96L71	Gene names	CENTD2, ARAP1, KIAA0782
Domain Architecture
Description	Centaurin-delta 2 (Cnt-d2) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 1).

RHG07_MOUSE
NC score	0.621123 (rank : 43)	θ value	1.99992e-07 (rank : 53)
Query Neighborhood Hits	185	Target Neighborhood Hits	103	Shared Neighborhood Hits	61
SwissProt Accessions	Q9R0Z9, Q8R541	Gene names	Dlc1, Arhgap7, Stard12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein homolog) (Dlc-1) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

CE005_HUMAN
NC score	0.620878 (rank : 44)	θ value	1.06045e-08 (rank : 47)
Query Neighborhood Hits	185	Target Neighborhood Hits	213	Shared Neighborhood Hits	76
SwissProt Accessions	Q9NYF5, Q6PGQ2, Q9P0I7	Gene names	C5orf5
Domain Architecture
Description	Protein C5orf5 (GAP-like protein N61).

CE005_MOUSE
NC score	0.617749 (rank : 45)	θ value	2.36244e-08 (rank : 48)
Query Neighborhood Hits	185	Target Neighborhood Hits	238	Shared Neighborhood Hits	80
SwissProt Accessions	Q8K2H3	Gene names
Domain Architecture
Description	Protein C5orf5 homolog.

RHG07_HUMAN
NC score	0.616869 (rank : 46)	θ value	1.99992e-07 (rank : 52)
Query Neighborhood Hits	185	Target Neighborhood Hits	108	Shared Neighborhood Hits	62
SwissProt Accessions	Q96QB1, O14868, O43199, Q9C0E0	Gene names	DLC1, ARHGAP7, KIAA1723, STARD12
Domain Architecture
Description	Rho-GTPase-activating protein 7 (Rho-type GTPase-activating protein 7) (Deleted in liver cancer 1 protein) (Dlc-1) (HP protein) (StAR-related lipid transfer protein 12) (StARD12) (START domain-containing protein 12).

CEND3_MOUSE
NC score	0.595648 (rank : 47)	θ value	2.69671e-12 (rank : 33)
Query Neighborhood Hits	185	Target Neighborhood Hits	228	Shared Neighborhood Hits	61
SwissProt Accessions	Q8R5G7, Q5DTN4, Q6NVF1, Q8R5G6	Gene names	Centd3, Arap3, Drag1, Kiaa4097
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3) (Dual specificity Rho- and Arf-GTPase-activating protein 1).

STAR8_MOUSE
NC score	0.584488 (rank : 48)	θ value	1.29631e-06 (rank : 55)
Query Neighborhood Hits	185	Target Neighborhood Hits	101	Shared Neighborhood Hits	58
SwissProt Accessions	Q8K031, Q3UZC7, Q6A0A8, Q6P5E0, Q8R3X8	Gene names	Stard8, Kiaa0189
Domain Architecture	No domain graphic available
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

CEND3_HUMAN
NC score	0.584230 (rank : 49)	θ value	1.133e-10 (rank : 39)
Query Neighborhood Hits	185	Target Neighborhood Hits	275	Shared Neighborhood Hits	61
SwissProt Accessions	Q8WWN8	Gene names	CENTD3, ARAP3
Domain Architecture	No domain graphic available
Description	Centaurin-delta 3 (Cnt-d3) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 3).

STAR8_HUMAN
NC score	0.579462 (rank : 50)	θ value	4.45536e-07 (rank : 54)
Query Neighborhood Hits	185	Target Neighborhood Hits	216	Shared Neighborhood Hits	59
SwissProt Accessions	Q92502, Q5JST0	Gene names	STARD8, KIAA0189
Domain Architecture
Description	StAR-related lipid transfer protein 8 (StARD8) (START domain- containing protein 8).

STA13_HUMAN
NC score	0.563339 (rank : 51)	θ value	0.00298849 (rank : 60)
Query Neighborhood Hits	185	Target Neighborhood Hits	89	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Y3M8, Q5HYH1, Q5TAE3, Q6UN61, Q86TP6, Q86WQ3, Q86XT1	Gene names	STARD13, DLC2, GT650
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13) (46H23.2) (Deleted in liver cancer protein 2) (Rho GTPase-activating protein).

K1688_MOUSE
NC score	0.555543 (rank : 52)	θ value	1.53129e-07 (rank : 51)
Query Neighborhood Hits	185	Target Neighborhood Hits	188	Shared Neighborhood Hits	58
SwissProt Accessions	P59281, Q69ZD4, Q6P9R6	Gene names	Kiaa1688, D15Wsu169e
Domain Architecture	No domain graphic available
Description	Protein KIAA1688.

STA13_MOUSE
NC score	0.553601 (rank : 53)	θ value	0.00228821 (rank : 59)
Query Neighborhood Hits	185	Target Neighborhood Hits	89	Shared Neighborhood Hits	58
SwissProt Accessions	Q923Q2, Q8K369	Gene names	Stard13
Domain Architecture
Description	StAR-related lipid transfer protein 13 (StARD13) (START domain- containing protein 13).

CEND1_MOUSE
NC score	0.548346 (rank : 54)	θ value	1.74796e-11 (rank : 38)
Query Neighborhood Hits	185	Target Neighborhood Hits	260	Shared Neighborhood Hits	62
SwissProt Accessions	Q8BZ05, Q80TX2, Q8C3T2, Q8VEL6	Gene names	Centd1, Kiaa0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1).

K1688_HUMAN
NC score	0.544090 (rank : 55)	θ value	6.87365e-08 (rank : 49)
Query Neighborhood Hits	185	Target Neighborhood Hits	217	Shared Neighborhood Hits	59
SwissProt Accessions	Q9C0H5	Gene names	KIAA1688
Domain Architecture
Description	Protein KIAA1688.

CEND1_HUMAN
NC score	0.524491 (rank : 56)	θ value	2.13673e-09 (rank : 44)
Query Neighborhood Hits	185	Target Neighborhood Hits	284	Shared Neighborhood Hits	60
SwissProt Accessions	Q8WZ64, Q4W5D2, Q7Z2L5, Q96L70, Q96P49, Q9Y4E4	Gene names	CENTD1, ARAP2, KIAA0580
Domain Architecture	No domain graphic available
Description	Centaurin-delta 1 (Cnt-d1) (Arf-GAP, Rho-GAP, ankyrin repeat and pleckstrin homology domain-containing protein 2) (PARX protein).

MYO9B_MOUSE
NC score	0.448200 (rank : 57)	θ value	6.84181e-24 (rank : 8)
Query Neighborhood Hits	185	Target Neighborhood Hits	311	Shared Neighborhood Hits	101
SwissProt Accessions	Q9QY06, Q9QY07, Q9QY08, Q9QY09	Gene names	Myo9b, Myr5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

MYO9B_HUMAN
NC score	0.442724 (rank : 58)	θ value	3.07116e-24 (rank : 7)
Query Neighborhood Hits	185	Target Neighborhood Hits	641	Shared Neighborhood Hits	105
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

P85A_HUMAN
NC score	0.395640 (rank : 59)	θ value	2.21117e-06 (rank : 56)
Query Neighborhood Hits	185	Target Neighborhood Hits	479	Shared Neighborhood Hits	91
SwissProt Accessions	P27986	Gene names	PIK3R1, GRB1
Domain Architecture	No domain graphic available
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

P85A_MOUSE
NC score	0.386137 (rank : 60)	θ value	1.43324e-05 (rank : 58)
Query Neighborhood Hits	185	Target Neighborhood Hits	435	Shared Neighborhood Hits	84
SwissProt Accessions	P26450	Gene names	Pik3r1
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase p85-subunit alpha) (PtdIns-3-kinase p85-alpha) (PI3K).

OCRL_HUMAN
NC score	0.286606 (rank : 61)	θ value	1.38821 (rank : 107)
Query Neighborhood Hits	185	Target Neighborhood Hits	77	Shared Neighborhood Hits	50
SwissProt Accessions	Q01968, O60800, Q15684, Q15774, Q5JQF1, Q5JQF2, Q9UJG5, Q9UMA5	Gene names	OCRL, INPP5F, OCRL1
Domain Architecture
Description	Inositol polyphosphate 5-phosphatase OCRL-1 (EC 3.1.3.36) (Lowe oculocerebrorenal syndrome protein).

I5P2_HUMAN
NC score	0.278712 (rank : 62)	θ value	θ > 10 (rank : 228)
Query Neighborhood Hits	185	Target Neighborhood Hits	86	Shared Neighborhood Hits	51
SwissProt Accessions	P32019, Q5VSG9, Q5VSH0, Q5VSH1, Q658Q5, Q6P6D4, Q6PD53, Q86YE1	Gene names	INPP5B
Domain Architecture	No domain graphic available
Description	Type II inositol-1,4,5-trisphosphate 5-phosphatase precursor (EC 3.1.3.36) (Phosphoinositide 5-phosphatase) (5PTase) (75 kDa inositol polyphosphate-5-phosphatase).

GRP3_HUMAN
NC score	0.161910 (rank : 63)	θ value	0.0736092 (rank : 70)
Query Neighborhood Hits	185	Target Neighborhood Hits	131	Shared Neighborhood Hits	46
SwissProt Accessions	Q8IV61, O94931	Gene names	RASGRP3, GRP3, KIAA0846
Domain Architecture
Description	RAS guanyl-releasing protein 3 (Calcium and DAG-regulated guanine nucleotide exchange factor III) (Guanine nucleotide exchange factor for Rap1).

P85B_HUMAN
NC score	0.130542 (rank : 64)	θ value	θ > 10 (rank : 265)
Query Neighborhood Hits	185	Target Neighborhood Hits	543	Shared Neighborhood Hits	70
SwissProt Accessions	O00459, Q9UPH9	Gene names	PIK3R2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

PDZD8_HUMAN
NC score	0.110267 (rank : 65)	θ value	6.88961 (rank : 170)
Query Neighborhood Hits	185	Target Neighborhood Hits	185	Shared Neighborhood Hits	42
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

DGKQ_HUMAN
NC score	0.096338 (rank : 66)	θ value	0.163984 (rank : 71)
Query Neighborhood Hits	185	Target Neighborhood Hits	131	Shared Neighborhood Hits	41
SwissProt Accessions	P52824	Gene names	DGKQ, DAGK4
Domain Architecture
Description	Diacylglycerol kinase theta (EC 2.7.1.107) (Diglyceride kinase theta) (DGK-theta) (DAG kinase theta).

RASF1_MOUSE
NC score	0.095181 (rank : 67)	θ value	θ > 10 (rank : 273)
Query Neighborhood Hits	185	Target Neighborhood Hits	74	Shared Neighborhood Hits	35
SwissProt Accessions	Q99MK9, Q9WUF5	Gene names	Rassf1
Domain Architecture	No domain graphic available
Description	Ras association domain-containing protein 1 (Protein 123F2).

RASF5_HUMAN
NC score	0.092575 (rank : 68)	θ value	0.279714 (rank : 79)
Query Neighborhood Hits	185	Target Neighborhood Hits	79	Shared Neighborhood Hits	32
SwissProt Accessions	Q8WWW0, Q5SY32, Q8WWV9, Q8WXF4, Q9BT99	Gene names	RASSF5, NORE1, RAPL
Domain Architecture	No domain graphic available
Description	Ras association domain-containing family protein 5 (New ras effector 1) (Regulator for cell adhesion and polarization enriched in lymphoid tissues) (RAPL).

UN13A_HUMAN
NC score	0.092461 (rank : 69)	θ value	θ > 10 (rank : 292)
Query Neighborhood Hits	185	Target Neighborhood Hits	285	Shared Neighborhood Hits	52
SwissProt Accessions	Q9UPW8	Gene names	UNC13A, KIAA1032
Domain Architecture	No domain graphic available
Description	Unc-13 homolog A (Munc13-1).

P85B_MOUSE
NC score	0.091907 (rank : 70)	θ value	θ > 10 (rank : 266)
Query Neighborhood Hits	185	Target Neighborhood Hits	519	Shared Neighborhood Hits	65
SwissProt Accessions	O08908	Gene names	Pik3r2
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit beta (PI3-kinase p85- subunit beta) (PtdIns-3-kinase p85-beta).

UN13B_HUMAN
NC score	0.091587 (rank : 71)	θ value	θ > 10 (rank : 293)
Query Neighborhood Hits	185	Target Neighborhood Hits	217	Shared Neighborhood Hits	51
SwissProt Accessions	O14795	Gene names	UNC13B, UNC13
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

STAC3_MOUSE
NC score	0.088762 (rank : 72)	θ value	θ > 10 (rank : 284)
Query Neighborhood Hits	185	Target Neighborhood Hits	232	Shared Neighborhood Hits	50
SwissProt Accessions	Q8BZ71	Gene names	Stac3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

CENB2_HUMAN
NC score	0.087231 (rank : 73)	θ value	θ > 10 (rank : 200)
Query Neighborhood Hits	185	Target Neighborhood Hits	425	Shared Neighborhood Hits	24
SwissProt Accessions	Q15057, Q9UQR3	Gene names	CENTB2, KIAA0041
Domain Architecture
Description	Centaurin-beta 2 (Cnt-b2).

STAC3_HUMAN
NC score	0.087013 (rank : 74)	θ value	θ > 10 (rank : 283)
Query Neighborhood Hits	185	Target Neighborhood Hits	228	Shared Neighborhood Hits	51
SwissProt Accessions	Q96MF2, Q96HU5	Gene names	STAC3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

UN13B_MOUSE
NC score	0.085117 (rank : 75)	θ value	θ > 10 (rank : 294)
Query Neighborhood Hits	185	Target Neighborhood Hits	210	Shared Neighborhood Hits	49
SwissProt Accessions	Q9Z1N9	Gene names	Unc13b, Unc13a
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

CENB5_HUMAN
NC score	0.080864 (rank : 76)	θ value	θ > 10 (rank : 201)
Query Neighborhood Hits	185	Target Neighborhood Hits	395	Shared Neighborhood Hits	17
SwissProt Accessions	Q96P50, Q9BSR9, Q9C0E7	Gene names	CENTB5, KIAA1716
Domain Architecture
Description	Centaurin-beta 5 (Cnt-b5).

RASF1_HUMAN
NC score	0.080618 (rank : 77)	θ value	θ > 10 (rank : 272)
Query Neighborhood Hits	185	Target Neighborhood Hits	62	Shared Neighborhood Hits	31
SwissProt Accessions	Q9NS23, O14571, O60539, O60710, Q9HB04, Q9HB18, Q9NS22, Q9UND4, Q9UND5	Gene names	RASSF1, RDA32
Domain Architecture	No domain graphic available
Description	Ras association domain-containing protein 1.

RASF5_MOUSE
NC score	0.079800 (rank : 78)	θ value	2.36792 (rank : 123)
Query Neighborhood Hits	185	Target Neighborhood Hits	72	Shared Neighborhood Hits	34
SwissProt Accessions	Q5EBH1, O70407, Q6KAR0, Q8C2E8	Gene names	Rassf5, Nore1, Rapl
Domain Architecture	No domain graphic available
Description	Ras association domain-containing family protein 5 (New ras effector 1) (Regulator for cell adhesion and polarization enriched in lymphoid tissues) (RAPL).

CENB1_HUMAN
NC score	0.079192 (rank : 79)	θ value	θ > 10 (rank : 199)
Query Neighborhood Hits	185	Target Neighborhood Hits	383	Shared Neighborhood Hits	14
SwissProt Accessions	Q15027	Gene names	CENTB1, KIAA0050
Domain Architecture
Description	Centaurin-beta 1 (Cnt-b1).

DGKH_HUMAN
NC score	0.078544 (rank : 80)	θ value	θ > 10 (rank : 215)
Query Neighborhood Hits	185	Target Neighborhood Hits	255	Shared Neighborhood Hits	48
SwissProt Accessions	Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9	Gene names	DGKH
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).

ITSN1_HUMAN
NC score	0.077876 (rank : 81)	θ value	0.279714 (rank : 76)
Query Neighborhood Hits	185	Target Neighborhood Hits	1757	Shared Neighborhood Hits	99
SwissProt Accessions	Q15811, O95216, Q9UET5, Q9UK60, Q9UNK1, Q9UNK2, Q9UQ92	Gene names	ITSN1, ITSN, SH3D1A
Domain Architecture
Description	Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17).

RGNEF_MOUSE
NC score	0.077567 (rank : 82)	θ value	0.0431538 (rank : 69)
Query Neighborhood Hits	185	Target Neighborhood Hits	641	Shared Neighborhood Hits	82
SwissProt Accessions	P97433	Gene names	Rgnef, Rhoip2
Domain Architecture
Description	Rho-guanine nucleotide exchange factor (Rho-interacting protein 2) (RhoGEF) (RIP2).

STAC_MOUSE
NC score	0.076926 (rank : 83)	θ value	θ > 10 (rank : 286)
Query Neighborhood Hits	185	Target Neighborhood Hits	268	Shared Neighborhood Hits	48
SwissProt Accessions	P97306	Gene names	Stac
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

MYO10_HUMAN
NC score	0.075807 (rank : 84)	θ value	θ > 10 (rank : 247)
Query Neighborhood Hits	185	Target Neighborhood Hits	920	Shared Neighborhood Hits	74
SwissProt Accessions	Q9HD67, Q9NYM7, Q9P110, Q9P111, Q9UHF6	Gene names	MYO10
Domain Architecture
Description	Myosin-10 (Myosin X).

ITSN1_MOUSE
NC score	0.073907 (rank : 85)	θ value	2.36792 (rank : 117)
Query Neighborhood Hits	185	Target Neighborhood Hits	1669	Shared Neighborhood Hits	98
SwissProt Accessions	Q9Z0R4, Q9R143	Gene names	Itsn1, Ese1, Itsn
Domain Architecture
Description	Intersectin-1 (EH and SH3 domains protein 1).

VAV3_HUMAN
NC score	0.073608 (rank : 86)	θ value	θ > 10 (rank : 297)
Query Neighborhood Hits	185	Target Neighborhood Hits	398	Shared Neighborhood Hits	48
SwissProt Accessions	Q9UKW4, O95230, Q9Y5X8	Gene names	VAV3
Domain Architecture
Description	Protein vav-3.

MY18A_HUMAN
NC score	0.073603 (rank : 87)	θ value	0.21417 (rank : 74)
Query Neighborhood Hits	185	Target Neighborhood Hits	1929	Shared Neighborhood Hits	93
SwissProt Accessions	Q92614, Q8IXP8	Gene names	MYO18A, KIAA0216, MYSPDZ
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

VAV3_MOUSE
NC score	0.072975 (rank : 88)	θ value	θ > 10 (rank : 298)
Query Neighborhood Hits	185	Target Neighborhood Hits	404	Shared Neighborhood Hits	50
SwissProt Accessions	Q9R0C8, Q7TS85	Gene names	Vav3
Domain Architecture
Description	Protein vav-3.

ITSN2_MOUSE
NC score	0.072235 (rank : 89)	θ value	2.36792 (rank : 118)
Query Neighborhood Hits	185	Target Neighborhood Hits	1371	Shared Neighborhood Hits	88
SwissProt Accessions	Q9Z0R6, Q9Z0R5	Gene names	Itsn2, Ese2, Sh3d1B
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (EH and SH3 domains protein 2) (EH domain and SH3 domain regulator of endocytosis 2).

MY18A_MOUSE
NC score	0.071102 (rank : 90)	θ value	0.62314 (rank : 87)
Query Neighborhood Hits	185	Target Neighborhood Hits	1989	Shared Neighborhood Hits	94
SwissProt Accessions	Q9JMH9, Q811D7	Gene names	Myo18a, Myspdz
Domain Architecture
Description	Myosin-18A (Myosin XVIIIa) (Myosin containing PDZ domain) (Molecule associated with JAK3 N-terminus) (MAJN).

STAC_HUMAN
NC score	0.070135 (rank : 91)	θ value	θ > 10 (rank : 285)
Query Neighborhood Hits	185	Target Neighborhood Hits	276	Shared Neighborhood Hits	49
SwissProt Accessions	Q99469	Gene names	STAC
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

P55G_HUMAN
NC score	0.069972 (rank : 92)	θ value	θ > 10 (rank : 263)
Query Neighborhood Hits	185	Target Neighborhood Hits	451	Shared Neighborhood Hits	48
SwissProt Accessions	Q92569, O60482	Gene names	PIK3R3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

DGKD_HUMAN
NC score	0.069751 (rank : 93)	θ value	θ > 10 (rank : 214)
Query Neighborhood Hits	185	Target Neighborhood Hits	231	Shared Neighborhood Hits	50
SwissProt Accessions	Q16760, Q14158, Q6PK55, Q8NG53	Gene names	DGKD, KIAA0145
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase delta (EC 2.7.1.107) (Diglyceride kinase delta) (DGK-delta) (DAG kinase delta) (130 kDa diacylglycerol kinase).

ITSN2_HUMAN
NC score	0.069747 (rank : 94)	θ value	4.03905 (rank : 146)
Query Neighborhood Hits	185	Target Neighborhood Hits	1173	Shared Neighborhood Hits	77
SwissProt Accessions	Q9NZM3, O95062, Q15812, Q9HAK4, Q9NXE6, Q9NYG0, Q9NZM2, Q9ULG4	Gene names	ITSN2, KIAA1256, SH3D1B, SWAP
Domain Architecture
Description	Intersectin-2 (SH3 domain-containing protein 1B) (SH3P18) (SH3P18-like WASP-associated protein).

CIP4_HUMAN
NC score	0.069583 (rank : 95)	θ value	θ > 10 (rank : 203)
Query Neighborhood Hits	185	Target Neighborhood Hits	374	Shared Neighborhood Hits	47
SwissProt Accessions	Q15642, O15184, Q5TZN1	Gene names	TRIP10, CIP4
Domain Architecture
Description	Cdc42-interacting protein 4 (Thyroid receptor-interacting protein 10) (TRIP-10).

MYH3_HUMAN
NC score	0.069319 (rank : 96)	θ value	0.365318 (rank : 83)
Query Neighborhood Hits	185	Target Neighborhood Hits	1660	Shared Neighborhood Hits	86
SwissProt Accessions	P11055, Q15492	Gene names	MYH3
Domain Architecture
Description	Myosin heavy chain, fast skeletal muscle, embryonic (Muscle embryonic myosin heavy chain) (SMHCE).

MYH8_HUMAN
NC score	0.066767 (rank : 97)	θ value	6.88961 (rank : 168)
Query Neighborhood Hits	185	Target Neighborhood Hits	1610	Shared Neighborhood Hits	90
SwissProt Accessions	P13535, Q14910	Gene names	MYH8
Domain Architecture
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

NCK2_HUMAN
NC score	0.066284 (rank : 98)	θ value	θ > 10 (rank : 261)
Query Neighborhood Hits	185	Target Neighborhood Hits	310	Shared Neighborhood Hits	20
SwissProt Accessions	O43639, Q9BWN9, Q9UIC3	Gene names	NCK2
Domain Architecture
Description	Cytoplasmic protein NCK2 (NCK adaptor protein 2) (SH2/SH3 adaptor protein NCK-beta) (Nck-2).

VAV2_HUMAN
NC score	0.066222 (rank : 99)	θ value	θ > 10 (rank : 295)
Query Neighborhood Hits	185	Target Neighborhood Hits	453	Shared Neighborhood Hits	55
SwissProt Accessions	P52735	Gene names	VAV2
Domain Architecture
Description	Protein vav-2.

P55G_MOUSE
NC score	0.065274 (rank : 100)	θ value	θ > 10 (rank : 264)
Query Neighborhood Hits	185	Target Neighborhood Hits	401	Shared Neighborhood Hits	41
SwissProt Accessions	Q64143	Gene names	Pik3r3
Domain Architecture
Description	Phosphatidylinositol 3-kinase regulatory subunit gamma (PI3-kinase p85-subunit gamma) (PtdIns-3-kinase p85-gamma) (p55PIK).

VAV2_MOUSE
NC score	0.065040 (rank : 101)	θ value	θ > 10 (rank : 296)
Query Neighborhood Hits	185	Target Neighborhood Hits	456	Shared Neighborhood Hits	49
SwissProt Accessions	Q60992	Gene names	Vav2
Domain Architecture
Description	Protein vav-2.

MYO5C_HUMAN
NC score	0.064930 (rank : 102)	θ value	θ > 10 (rank : 256)
Query Neighborhood Hits	185	Target Neighborhood Hits	1206	Shared Neighborhood Hits	79
SwissProt Accessions	Q9NQX4	Gene names	MYO5C
Domain Architecture
Description	Myosin-5C (Myosin Vc).

CENPF_HUMAN
NC score	0.064776 (rank : 103)	θ value	0.0193708 (rank : 65)
Query Neighborhood Hits	185	Target Neighborhood Hits	1932	Shared Neighborhood Hits	96
SwissProt Accessions	P49454, Q13171, Q13246	Gene names	CENPF
Domain Architecture
Description	Centromere protein F (Kinetochore protein CENP-F) (Mitosin) (AH antigen).

MYH11_MOUSE
NC score	0.064512 (rank : 104)	θ value	θ > 10 (rank : 235)
Query Neighborhood Hits	185	Target Neighborhood Hits	1777	Shared Neighborhood Hits	90
SwissProt Accessions	O08638, O08639, Q62462, Q64195	Gene names	Myh11
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYH9_MOUSE
NC score	0.064366 (rank : 105)	θ value	8.99809 (rank : 182)
Query Neighborhood Hits	185	Target Neighborhood Hits	1829	Shared Neighborhood Hits	89
SwissProt Accessions	Q8VDD5	Gene names	Myh9
Domain Architecture	No domain graphic available
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

DGKB_HUMAN
NC score	0.064208 (rank : 106)	θ value	5.27518 (rank : 159)
Query Neighborhood Hits	185	Target Neighborhood Hits	238	Shared Neighborhood Hits	41
SwissProt Accessions	Q9Y6T7, O75241, Q75MF9, Q75MU7, Q86UI5, Q86UM9, Q9UQ29	Gene names	DGKB, DAGK2, KIAA0718
Domain Architecture
Description	Diacylglycerol kinase beta (EC 2.7.1.107) (Diglyceride kinase beta) (DGK-beta) (DAG kinase beta) (90 kDa diacylglycerol kinase).

FA13A_HUMAN
NC score	0.064033 (rank : 107)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	185	Target Neighborhood Hits	102	Shared Neighborhood Hits	13
SwissProt Accessions	O94988, Q8NBA3	Gene names	FAM13A1, KIAA0914
Domain Architecture	No domain graphic available
Description	Protein FAM13A1.

MYH8_MOUSE
NC score	0.063933 (rank : 108)	θ value	θ > 10 (rank : 246)
Query Neighborhood Hits	185	Target Neighborhood Hits	1600	Shared Neighborhood Hits	84
SwissProt Accessions	P13542, Q5SX36	Gene names	Myh8, Myhsp
Domain Architecture	No domain graphic available
Description	Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal) (MyHC- perinatal).

MYH11_HUMAN
NC score	0.063824 (rank : 109)	θ value	θ > 10 (rank : 234)
Query Neighborhood Hits	185	Target Neighborhood Hits	1806	Shared Neighborhood Hits	89
SwissProt Accessions	P35749, O00396, O94944, P78422	Gene names	MYH11, KIAA0866
Domain Architecture
Description	Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC).

MYH9_HUMAN
NC score	0.063625 (rank : 110)	θ value	8.99809 (rank : 181)
Query Neighborhood Hits	185	Target Neighborhood Hits	1762	Shared Neighborhood Hits	88
SwissProt Accessions	P35579, O60805	Gene names	MYH9
Domain Architecture
Description	Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A).

TPM1_HUMAN
NC score	0.063442 (rank : 111)	θ value	1.38821 (rank : 109)
Query Neighborhood Hits	185	Target Neighborhood Hits	716	Shared Neighborhood Hits	65
SwissProt Accessions	P09493, P09494, P10469, Q86W64, Q96IK2, Q9UCY9	Gene names	TPM1, TMSA
Domain Architecture
Description	Tropomyosin 1 alpha chain (Alpha-tropomyosin).

MYH4_HUMAN
NC score	0.063358 (rank : 112)	θ value	θ > 10 (rank : 241)
Query Neighborhood Hits	185	Target Neighborhood Hits	1377	Shared Neighborhood Hits	83
SwissProt Accessions	Q9Y623	Gene names	MYH4
Domain Architecture
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal) (Myosin heavy chain IIb) (MyHC-IIb).

FA13A_MOUSE
NC score	0.062929 (rank : 113)	θ value	θ > 10 (rank : 219)
Query Neighborhood Hits	185	Target Neighborhood Hits	83	Shared Neighborhood Hits	12
SwissProt Accessions	Q8BGI4, Q8BZ91	Gene names	Fam13a1, Precm1
Domain Architecture	No domain graphic available
Description	Protein FAM13A1 (Precm1 protein).

GRAP_HUMAN
NC score	0.062898 (rank : 114)	θ value	θ > 10 (rank : 222)
Query Neighborhood Hits	185	Target Neighborhood Hits	307	Shared Neighborhood Hits	18
SwissProt Accessions	Q13588	Gene names	GRAP
Domain Architecture
Description	GRB2-related adapter protein.

TPM3_MOUSE
NC score	0.062603 (rank : 115)	θ value	0.62314 (rank : 89)
Query Neighborhood Hits	185	Target Neighborhood Hits	676	Shared Neighborhood Hits	62
SwissProt Accessions	P21107, Q09021, Q60606, Q80SW6, Q9EPW3	Gene names	Tpm3, Tpm-5, Tpm5
Domain Architecture
Description	Tropomyosin alpha-3 chain (Tropomyosin-3) (Tropomyosin gamma).

TPM1_MOUSE
NC score	0.062602 (rank : 116)	θ value	1.38821 (rank : 110)
Query Neighborhood Hits	185	Target Neighborhood Hits	729	Shared Neighborhood Hits	64
SwissProt Accessions	P58771, P02558, P19354, P46902, P99034	Gene names	Tpm1, Tpm-1, Tpma
Domain Architecture
Description	Tropomyosin 1 alpha chain (Alpha-tropomyosin).

DDEF2_HUMAN
NC score	0.062385 (rank : 117)	θ value	θ > 10 (rank : 210)
Query Neighborhood Hits	185	Target Neighborhood Hits	599	Shared Neighborhood Hits	25
SwissProt Accessions	O43150	Gene names	DDEF2, KIAA0400
Domain Architecture
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

MYO5A_MOUSE
NC score	0.062368 (rank : 118)	θ value	θ > 10 (rank : 254)
Query Neighborhood Hits	185	Target Neighborhood Hits	1117	Shared Neighborhood Hits	74
SwissProt Accessions	Q99104	Gene names	Myo5a, Dilute
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle).

MYH1_HUMAN
NC score	0.062267 (rank : 119)	θ value	θ > 10 (rank : 238)
Query Neighborhood Hits	185	Target Neighborhood Hits	1478	Shared Neighborhood Hits	84
SwissProt Accessions	P12882, Q9Y622	Gene names	MYH1
Domain Architecture
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1) (Myosin heavy chain IIx/d) (MyHC-IIx/d).

PKHA1_HUMAN
NC score	0.062124 (rank : 120)	θ value	θ > 10 (rank : 268)
Query Neighborhood Hits	185	Target Neighborhood Hits	127	Shared Neighborhood Hits	17
SwissProt Accessions	Q9HB21, Q9BVK0	Gene names	PLEKHA1, TAPP1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

MYH1_MOUSE
NC score	0.061899 (rank : 121)	θ value	θ > 10 (rank : 239)
Query Neighborhood Hits	185	Target Neighborhood Hits	1461	Shared Neighborhood Hits	85
SwissProt Accessions	Q5SX40	Gene names	Myh1
Domain Architecture	No domain graphic available
Description	Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1).

REST_HUMAN
NC score	0.061774 (rank : 122)	θ value	0.0148317 (rank : 64)
Query Neighborhood Hits	185	Target Neighborhood Hits	1605	Shared Neighborhood Hits	82
SwissProt Accessions	P30622	Gene names	RSN, CYLN1
Domain Architecture
Description	Restin (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed- Sternberg intermediate filament-associated protein) (Cytoplasmic linker protein 1).

MYH2_HUMAN
NC score	0.061753 (rank : 123)	θ value	θ > 10 (rank : 240)
Query Neighborhood Hits	185	Target Neighborhood Hits	1491	Shared Neighborhood Hits	84
SwissProt Accessions	Q9UKX2, Q14322, Q16229	Gene names	MYH2, MYHSA2
Domain Architecture
Description	Myosin heavy chain, skeletal muscle, adult 2 (Myosin heavy chain IIa) (MyHC-IIa).

TPM3_HUMAN
NC score	0.061644 (rank : 124)	θ value	0.813845 (rank : 96)
Query Neighborhood Hits	185	Target Neighborhood Hits	689	Shared Neighborhood Hits	62
SwissProt Accessions	P06753, P12324, Q969Q2, Q9NQH8	Gene names	TPM3
Domain Architecture
Description	Tropomyosin alpha-3 chain (Tropomyosin-3) (Tropomyosin gamma) (hTM5).

MYO5A_HUMAN
NC score	0.061608 (rank : 125)	θ value	θ > 10 (rank : 253)
Query Neighborhood Hits	185	Target Neighborhood Hits	1092	Shared Neighborhood Hits	76
SwissProt Accessions	Q9Y4I1, O60653, Q07902, Q16249, Q9UE30, Q9UE31	Gene names	MYO5A, MYH12
Domain Architecture
Description	Myosin-5A (Myosin Va) (Dilute myosin heavy chain, non-muscle) (Myosin heavy chain 12) (Myoxin).

DDEF2_MOUSE
NC score	0.061552 (rank : 126)	θ value	θ > 10 (rank : 211)
Query Neighborhood Hits	185	Target Neighborhood Hits	625	Shared Neighborhood Hits	24
SwissProt Accessions	Q7SIG6, Q501K1, Q66JN2	Gene names	Ddef2
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor 2 (Pyk2 C-terminus- associated protein) (PAP) (Paxillin-associated protein with ARFGAP activity 3) (PAG3).

MYO5B_HUMAN
NC score	0.061548 (rank : 127)	θ value	θ > 10 (rank : 255)
Query Neighborhood Hits	185	Target Neighborhood Hits	911	Shared Neighborhood Hits	68
SwissProt Accessions	Q9ULV0	Gene names	MYO5B, KIAA1119
Domain Architecture
Description	Myosin-5B (Myosin Vb).

MY18B_HUMAN
NC score	0.061467 (rank : 128)	θ value	θ > 10 (rank : 231)
Query Neighborhood Hits	185	Target Neighborhood Hits	1299	Shared Neighborhood Hits	77
SwissProt Accessions	Q8IUG5, Q8NDI8, Q8TE65, Q8WWS0, Q96KH2, Q96KR8, Q96KR9	Gene names	MYO18B
Domain Architecture
Description	Myosin-18B (Myosin XVIIIb).

MYH4_MOUSE
NC score	0.060810 (rank : 129)	θ value	θ > 10 (rank : 242)
Query Neighborhood Hits	185	Target Neighborhood Hits	1476	Shared Neighborhood Hits	84
SwissProt Accessions	Q5SX39	Gene names	Myh4
Domain Architecture	No domain graphic available
Description	Myosin-4 (Myosin heavy chain, skeletal muscle, fetal).

MRIP_MOUSE
NC score	0.060533 (rank : 130)	θ value	0.279714 (rank : 78)
Query Neighborhood Hits	185	Target Neighborhood Hits	569	Shared Neighborhood Hits	53
SwissProt Accessions	P97434, Q3TBR5, Q3TC85, Q3TRS0, Q3U1Y8, Q3U3E4, Q5SWZ3, Q5SWZ4, Q5SWZ7, Q6P559, Q80YC8	Gene names	Mrip, Kiaa0864, Rhoip3
Domain Architecture
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (p116Rip) (RIP3).

MYH10_HUMAN
NC score	0.060433 (rank : 131)	θ value	θ > 10 (rank : 232)
Query Neighborhood Hits	185	Target Neighborhood Hits	1620	Shared Neighborhood Hits	82
SwissProt Accessions	P35580, Q16087	Gene names	MYH10
Domain Architecture
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH10_MOUSE
NC score	0.060431 (rank : 132)	θ value	θ > 10 (rank : 233)
Query Neighborhood Hits	185	Target Neighborhood Hits	1612	Shared Neighborhood Hits	82
SwissProt Accessions	Q61879, Q5SV63	Gene names	Myh10
Domain Architecture	No domain graphic available
Description	Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin heavy chain, type B) (Nonmuscle myosin heavy chain-B) (NMMHC-B).

MYH6_MOUSE
NC score	0.060292 (rank : 133)	θ value	θ > 10 (rank : 244)
Query Neighborhood Hits	185	Target Neighborhood Hits	1501	Shared Neighborhood Hits	78
SwissProt Accessions	Q02566, Q64258, Q64738	Gene names	Myh6, Myhca
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

GRAP_MOUSE
NC score	0.060244 (rank : 134)	θ value	θ > 10 (rank : 223)
Query Neighborhood Hits	185	Target Neighborhood Hits	309	Shared Neighborhood Hits	18
SwissProt Accessions	Q9CX99, Q3U545	Gene names	Grap
Domain Architecture	No domain graphic available
Description	GRB2-related adapter protein.

MRIP_HUMAN
NC score	0.060013 (rank : 135)	θ value	0.365318 (rank : 82)
Query Neighborhood Hits	185	Target Neighborhood Hits	578	Shared Neighborhood Hits	55
SwissProt Accessions	Q6WCQ1, Q3KQZ5, Q5FB94, Q6DHW2, Q7Z5Y2, Q8N390, Q96G40	Gene names	MRIP, KIAA0864, RHOIP3
Domain Architecture	No domain graphic available
Description	Myosin phosphatase Rho-interacting protein (Rho-interacting protein 3) (M-RIP) (RIP3) (p116Rip).

MYO1F_HUMAN
NC score	0.059988 (rank : 136)	θ value	θ > 10 (rank : 251)
Query Neighborhood Hits	185	Target Neighborhood Hits	275	Shared Neighborhood Hits	23
SwissProt Accessions	O00160, Q8WWN7	Gene names	MYO1F
Domain Architecture
Description	Myosin If (Myosin-IE).

MYO1F_MOUSE
NC score	0.059872 (rank : 137)	θ value	θ > 10 (rank : 252)
Query Neighborhood Hits	185	Target Neighborhood Hits	262	Shared Neighborhood Hits	22
SwissProt Accessions	P70248	Gene names	Myo1f
Domain Architecture
Description	Myosin If.

CCD96_HUMAN
NC score	0.059725 (rank : 138)	θ value	1.38821 (rank : 102)
Query Neighborhood Hits	185	Target Neighborhood Hits	595	Shared Neighborhood Hits	60
SwissProt Accessions	Q2M329, Q8N2I7	Gene names	CCDC96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

MYH6_HUMAN
NC score	0.059445 (rank : 139)	θ value	θ > 10 (rank : 243)
Query Neighborhood Hits	185	Target Neighborhood Hits	1426	Shared Neighborhood Hits	79
SwissProt Accessions	P13533, Q13943, Q14906, Q14907	Gene names	MYH6, MYHCA
Domain Architecture
Description	Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha).

MYH14_MOUSE
NC score	0.059282 (rank : 140)	θ value	8.99809 (rank : 180)
Query Neighborhood Hits	185	Target Neighborhood Hits	1225	Shared Neighborhood Hits	76
SwissProt Accessions	Q6URW6, Q80V64, Q80ZE6	Gene names	Myh14
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

TPM2_HUMAN
NC score	0.059025 (rank : 141)	θ value	3.0926 (rank : 139)
Query Neighborhood Hits	185	Target Neighborhood Hits	677	Shared Neighborhood Hits	62
SwissProt Accessions	P07951, P06468, Q13894, Q53FM4, Q5TCU4, Q5TCU7, Q9UH67	Gene names	TPM2, TMSB
Domain Architecture
Description	Tropomyosin beta chain (Tropomyosin 2) (Beta-tropomyosin).

GRB2_HUMAN
NC score	0.058968 (rank : 142)	θ value	θ > 10 (rank : 224)
Query Neighborhood Hits	185	Target Neighborhood Hits	310	Shared Neighborhood Hits	18
SwissProt Accessions	P62993, P29354, Q14450, Q63057, Q63059	Gene names	GRB2, ASH
Domain Architecture	No domain graphic available
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2) (Protein Ash).

GRB2_MOUSE
NC score	0.058954 (rank : 143)	θ value	θ > 10 (rank : 225)
Query Neighborhood Hits	185	Target Neighborhood Hits	312	Shared Neighborhood Hits	18
SwissProt Accessions	Q60631, Q61240	Gene names	Grb2
Domain Architecture
Description	Growth factor receptor-bound protein 2 (Adapter protein GRB2) (SH2/SH3 adapter GRB2).

CYLN2_MOUSE
NC score	0.058834 (rank : 144)	θ value	5.27518 (rank : 156)
Query Neighborhood Hits	185	Target Neighborhood Hits	1002	Shared Neighborhood Hits	77
SwissProt Accessions	Q9Z0H8, Q7TSI9, Q8CHU1, Q9EP81	Gene names	Cyln2, Kiaa0291
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115).

TAXB1_MOUSE
NC score	0.058737 (rank : 145)	θ value	2.36792 (rank : 125)
Query Neighborhood Hits	185	Target Neighborhood Hits	886	Shared Neighborhood Hits	77
SwissProt Accessions	Q3UKC1, Q91YT6, Q9CVF0, Q9DC45	Gene names	Tax1bp1
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 homolog.

TAXB1_HUMAN
NC score	0.058701 (rank : 146)	θ value	0.47712 (rank : 85)
Query Neighborhood Hits	185	Target Neighborhood Hits	829	Shared Neighborhood Hits	71
SwissProt Accessions	Q86VP1, O60398, O95770, Q13311, Q9BQG5, Q9UI88	Gene names	TAX1BP1, T6BP
Domain Architecture	No domain graphic available
Description	Tax1-binding protein 1 (TRAF6-binding protein).

DDEF1_MOUSE
NC score	0.058586 (rank : 147)	θ value	θ > 10 (rank : 209)
Query Neighborhood Hits	185	Target Neighborhood Hits	592	Shared Neighborhood Hits	24
SwissProt Accessions	Q9QWY8, O08612, Q80TG8, Q80UV6, Q99LV8, Q9Z2B6	Gene names	Ddef1, Asap1, Kiaa1249, Shag1
Domain Architecture
Description	130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase- activating protein (PIP2-dependent ARF1 GAP) (ADP-ribosylation factor- directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (Differentiation-enhancing factor 1) (DEF-1).

MYH13_HUMAN
NC score	0.058476 (rank : 148)	θ value	θ > 10 (rank : 236)
Query Neighborhood Hits	185	Target Neighborhood Hits	1504	Shared Neighborhood Hits	83
SwissProt Accessions	Q9UKX3, O95252	Gene names	MYH13
Domain Architecture
Description	Myosin-13 (Myosin heavy chain, skeletal muscle, extraocular) (MyHC- eo).

DAPP1_MOUSE
NC score	0.058377 (rank : 149)	θ value	θ > 10 (rank : 208)
Query Neighborhood Hits	185	Target Neighborhood Hits	225	Shared Neighborhood Hits	11
SwissProt Accessions	Q9QXT1, Q9R178	Gene names	Dapp1, Bam32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (mDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

TPM2_MOUSE
NC score	0.058231 (rank : 150)	θ value	4.03905 (rank : 153)
Query Neighborhood Hits	185	Target Neighborhood Hits	676	Shared Neighborhood Hits	63
SwissProt Accessions	P58774, P02560, P46901	Gene names	Tpm2, Tpm-2
Domain Architecture
Description	Tropomyosin beta chain (Tropomyosin 2) (Beta-tropomyosin).

MYO1E_HUMAN
NC score	0.058156 (rank : 151)	θ value	θ > 10 (rank : 250)
Query Neighborhood Hits	185	Target Neighborhood Hits	293	Shared Neighborhood Hits	24
SwissProt Accessions	Q12965, Q14778	Gene names	MYO1E, MYO1C
Domain Architecture
Description	Myosin Ie (Myosin Ic).

VAV_MOUSE
NC score	0.057398 (rank : 152)	θ value	θ > 10 (rank : 300)
Query Neighborhood Hits	185	Target Neighborhood Hits	430	Shared Neighborhood Hits	48
SwissProt Accessions	P27870, Q8BTV7	Gene names	Vav1, Vav
Domain Architecture
Description	Proto-oncogene vav (p95vav).

CENA2_HUMAN
NC score	0.057315 (rank : 153)	θ value	θ > 10 (rank : 198)
Query Neighborhood Hits	185	Target Neighborhood Hits	83	Shared Neighborhood Hits	7
SwissProt Accessions	Q9NPF8, Q8N4Q6, Q96SD5	Gene names	CENTA2
Domain Architecture
Description	Centaurin-alpha 2.

MYO7A_MOUSE
NC score	0.057312 (rank : 154)	θ value	θ > 10 (rank : 260)
Query Neighborhood Hits	185	Target Neighborhood Hits	235	Shared Neighborhood Hits	26
SwissProt Accessions	P97479	Gene names	Myo7a, Myo7
Domain Architecture
Description	Myosin-7A (Myosin VIIa).

SMC2_MOUSE
NC score	0.057283 (rank : 155)	θ value	0.21417 (rank : 75)
Query Neighborhood Hits	185	Target Neighborhood Hits	1131	Shared Neighborhood Hits	72
SwissProt Accessions	Q8CG48, Q61076, Q9CS17, Q9CSD8	Gene names	Smc2l1, Cape, Fin16, Smc2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (XCAP-E homolog) (FGF-inducible protein 16).

MYH7_HUMAN
NC score	0.057118 (rank : 156)	θ value	θ > 10 (rank : 245)
Query Neighborhood Hits	185	Target Neighborhood Hits	1559	Shared Neighborhood Hits	83
SwissProt Accessions	P12883, Q14836, Q14837, Q14904, Q16579, Q92679, Q9H1D5, Q9UMM8	Gene names	MYH7, MYHCB
Domain Architecture
Description	Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta).

TCRG1_MOUSE
NC score	0.057073 (rank : 157)	θ value	θ > 10 (rank : 289)
Query Neighborhood Hits	185	Target Neighborhood Hits	947	Shared Neighborhood Hits	65
SwissProt Accessions	Q8CGF7, Q61051, Q8C490, Q8CHT8, Q9R0R5	Gene names	Tcerg1, Taf2s
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150) (p144) (Formin- binding protein 28) (FBP 28).

MYO6_HUMAN
NC score	0.057067 (rank : 158)	θ value	θ > 10 (rank : 257)
Query Neighborhood Hits	185	Target Neighborhood Hits	727	Shared Neighborhood Hits	57
SwissProt Accessions	Q9UM54, Q9BZZ7, Q9UEG2	Gene names	MYO6, KIAA0389
Domain Architecture
Description	Myosin-6 (Myosin VI).

DAPP1_HUMAN
NC score	0.056999 (rank : 159)	θ value	θ > 10 (rank : 207)
Query Neighborhood Hits	185	Target Neighborhood Hits	227	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UN19, Q8TCK5, Q9UHF2	Gene names	DAPP1, BAM32
Domain Architecture
Description	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3- phosphoinositide (hDAPP1) (B cell adapter molecule of 32 kDa) (B lymphocyte adapter protein Bam32).

PKHA1_MOUSE
NC score	0.056797 (rank : 160)	θ value	θ > 10 (rank : 269)
Query Neighborhood Hits	185	Target Neighborhood Hits	120	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BUL6, Q8BK96, Q8BXU1, Q8VE13	Gene names	Plekha1, Tapp1
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 1 (Tandem PH domain-containing protein 1) (TAPP-1).

TCRG1_HUMAN
NC score	0.056719 (rank : 161)	θ value	θ > 10 (rank : 288)
Query Neighborhood Hits	185	Target Neighborhood Hits	929	Shared Neighborhood Hits	64
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

SMP1L_HUMAN
NC score	0.056677 (rank : 162)	θ value	θ > 10 (rank : 279)
Query Neighborhood Hits	185	Target Neighborhood Hits	74	Shared Neighborhood Hits	6
SwissProt Accessions	Q8WU79, Q5QPL2, Q96C93, Q9NST2, Q9UJL8	Gene names	SMAP1L
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like.

DP13A_HUMAN
NC score	0.056402 (rank : 163)	θ value	θ > 10 (rank : 216)
Query Neighborhood Hits	185	Target Neighborhood Hits	107	Shared Neighborhood Hits	21
SwissProt Accessions	Q9UKG1, Q9P2B9	Gene names	APPL1, APPL, DIP13A, KIAA1428
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 alpha (Dip13 alpha) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 1).

SMP1L_MOUSE
NC score	0.056377 (rank : 164)	θ value	θ > 10 (rank : 280)
Query Neighborhood Hits	185	Target Neighborhood Hits	70	Shared Neighborhood Hits	5
SwissProt Accessions	Q7TN29, Q3U798	Gene names	Smap1l, Smap2
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1-like (Stromal membrane- associated protein 2).

CROCC_HUMAN
NC score	0.055925 (rank : 165)	θ value	1.06291 (rank : 99)
Query Neighborhood Hits	185	Target Neighborhood Hits	1409	Shared Neighborhood Hits	80
SwissProt Accessions	Q5TZA2, Q2VHY3, Q66GT7, Q7Z2L4, Q7Z5D7	Gene names	CROCC, KIAA0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

SMC2_HUMAN
NC score	0.055891 (rank : 166)	θ value	3.0926 (rank : 137)
Query Neighborhood Hits	185	Target Neighborhood Hits	1405	Shared Neighborhood Hits	77
SwissProt Accessions	O95347, Q9P1P2	Gene names	SMC2L1, CAPE, SMC2
Domain Architecture
Description	Structural maintenance of chromosome 2-like 1 protein (Chromosome- associated protein E) (hCAP-E) (XCAP-E homolog).

SM1L2_MOUSE
NC score	0.055870 (rank : 167)	θ value	0.279714 (rank : 80)
Query Neighborhood Hits	185	Target Neighborhood Hits	918	Shared Neighborhood Hits	74
SwissProt Accessions	Q920F6	Gene names	Smc1l2
Domain Architecture
Description	Structural maintenance of chromosomes 1-like 2 protein (SMC1beta protein).

DDFL1_HUMAN
NC score	0.055817 (rank : 168)	θ value	θ > 10 (rank : 212)
Query Neighborhood Hits	185	Target Neighborhood Hits	353	Shared Neighborhood Hits	11
SwissProt Accessions	Q8TDY4, Q6P9F4, Q86UY1, Q9NXK2	Gene names	DDEFL1, UPLC1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1 (Protein up- regulated in liver cancer 1).

MYH14_HUMAN
NC score	0.055781 (rank : 169)	θ value	θ > 10 (rank : 237)
Query Neighborhood Hits	185	Target Neighborhood Hits	995	Shared Neighborhood Hits	67
SwissProt Accessions	Q7Z406, Q5CZ75, Q6XYE4, Q76B62, Q8WV23, Q96I22, Q9BT27, Q9BW35, Q9H882	Gene names	MYH14, KIAA2034
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

MYO7A_HUMAN
NC score	0.055779 (rank : 170)	θ value	θ > 10 (rank : 259)
Query Neighborhood Hits	185	Target Neighborhood Hits	209	Shared Neighborhood Hits	25
SwissProt Accessions	Q13402, P78427, Q13321, Q14785, Q92821, Q92822	Gene names	MYO7A, USH1B
Domain Architecture
Description	Myosin-7A (Myosin VIIa).

CCD96_MOUSE
NC score	0.055717 (rank : 171)	θ value	1.38821 (rank : 103)
Query Neighborhood Hits	185	Target Neighborhood Hits	704	Shared Neighborhood Hits	59
SwissProt Accessions	Q9CR92	Gene names	Ccdc96
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 96.

VAV_HUMAN
NC score	0.055652 (rank : 172)	θ value	θ > 10 (rank : 299)
Query Neighborhood Hits	185	Target Neighborhood Hits	452	Shared Neighborhood Hits	53
SwissProt Accessions	P15498, Q15860	Gene names	VAV1, VAV
Domain Architecture
Description	Proto-oncogene vav.

MYO15_MOUSE
NC score	0.055618 (rank : 173)	θ value	θ > 10 (rank : 249)
Query Neighborhood Hits	185	Target Neighborhood Hits	467	Shared Neighborhood Hits	22
SwissProt Accessions	Q9QZZ4, O70395, Q9QWL6	Gene names	Myo15a, Myo15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

CYLN2_HUMAN
NC score	0.055268 (rank : 174)	θ value	4.03905 (rank : 142)
Query Neighborhood Hits	185	Target Neighborhood Hits	1004	Shared Neighborhood Hits	76
SwissProt Accessions	Q9UDT6, O14527, O43611	Gene names	CYLN2, KIAA0291, WBSCR4, WSCR4
Domain Architecture	No domain graphic available
Description	Cytoplasmic linker protein 2 (Cytoplasmic linker protein 115) (CLIP- 115) (Williams-Beuren syndrome chromosome region 4 protein).

MYO15_HUMAN
NC score	0.055169 (rank : 175)	θ value	θ > 10 (rank : 248)
Query Neighborhood Hits	185	Target Neighborhood Hits	671	Shared Neighborhood Hits	22
SwissProt Accessions	Q9UKN7	Gene names	MYO15A, MYO15
Domain Architecture
Description	Myosin-15 (Myosin XV) (Unconventional myosin-15).

SMAP1_HUMAN
NC score	0.055136 (rank : 176)	θ value	θ > 10 (rank : 277)
Query Neighborhood Hits	185	Target Neighborhood Hits	98	Shared Neighborhood Hits	7
SwissProt Accessions	Q8IYB5, Q53H70, Q5SYQ2, Q6PK24, Q8NDH4, Q96L38, Q96L39, Q9H8X4	Gene names	SMAP1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

MYO6_MOUSE
NC score	0.055073 (rank : 177)	θ value	θ > 10 (rank : 258)
Query Neighborhood Hits	185	Target Neighborhood Hits	586	Shared Neighborhood Hits	53
SwissProt Accessions	Q64331	Gene names	Myo6, Sv
Domain Architecture
Description	Myosin-6 (Myosin VI).

SMAP1_MOUSE
NC score	0.054938 (rank : 178)	θ value	θ > 10 (rank : 278)
Query Neighborhood Hits	185	Target Neighborhood Hits	120	Shared Neighborhood Hits	8
SwissProt Accessions	Q91VZ6, Q497I6, Q68EF3	Gene names	Smap1
Domain Architecture	No domain graphic available
Description	Stromal membrane-associated protein 1.

VINEX_MOUSE
NC score	0.054773 (rank : 179)	θ value	θ > 10 (rank : 302)
Query Neighborhood Hits	185	Target Neighborhood Hits	286	Shared Neighborhood Hits	20
SwissProt Accessions	Q9R1Z8, Q62423	Gene names	Sorbs3, Scam1, Sh3d4
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1) (SH3 domain-containing protein SH3P3).

CENA1_HUMAN
NC score	0.054456 (rank : 180)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	185	Target Neighborhood Hits	87	Shared Neighborhood Hits	7
SwissProt Accessions	O75689	Gene names	CENTA1
Domain Architecture	No domain graphic available
Description	Centaurin-alpha 1 (Putative MAPK-activating protein PM25).

CCD13_HUMAN
NC score	0.054372 (rank : 181)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	185	Target Neighborhood Hits	721	Shared Neighborhood Hits	67
SwissProt Accessions	Q8IYE1	Gene names	CCDC13
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 13.

BNIP2_HUMAN
NC score	0.054350 (rank : 182)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	185	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q12982	Gene names	BNIP2, NIP2
Domain Architecture
Description	BCL2/adenovirus E1B 19 kDa protein-interacting protein 2.

CI093_HUMAN
NC score	0.054324 (rank : 183)	θ value	θ > 10 (rank : 202)
Query Neighborhood Hits	185	Target Neighborhood Hits	1088	Shared Neighborhood Hits	78
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

BNIP2_MOUSE
NC score	0.054273 (rank : 184)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	185	Target Neighborhood Hits	23	Shared Neighborhood Hits	3
SwissProt Accessions	O54940	Gene names	Bnip2, Nip2l
Domain Architecture
Description	BCL2/adenovirus E1B 19 kDa protein-interacting protein 2.

DESP_HUMAN
NC score	0.054222 (rank : 185)	θ value	5.27518 (rank : 158)
Query Neighborhood Hits	185	Target Neighborhood Hits	1470	Shared Neighborhood Hits	81
SwissProt Accessions	P15924, O75993, Q14189, Q9UHN4	Gene names	DSP
Domain Architecture
Description	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen).

HMMR_MOUSE
NC score	0.053815 (rank : 186)	θ value	θ > 10 (rank : 226)
Query Neighborhood Hits	185	Target Neighborhood Hits	1178	Shared Neighborhood Hits	79
SwissProt Accessions	Q00547	Gene names	Hmmr, Ihabp, Rhamm
Domain Architecture
Description	Hyaluronan mediated motility receptor (Intracellular hyaluronic acid- binding protein) (Receptor for hyaluronan-mediated motility).

CING_MOUSE
NC score	0.053326 (rank : 187)	θ value	1.81305 (rank : 111)
Query Neighborhood Hits	185	Target Neighborhood Hits	1432	Shared Neighborhood Hits	83
SwissProt Accessions	P59242	Gene names	Cgn
Domain Architecture
Description	Cingulin.

CJ118_HUMAN
NC score	0.053196 (rank : 188)	θ value	1.06291 (rank : 98)
Query Neighborhood Hits	185	Target Neighborhood Hits	937	Shared Neighborhood Hits	69
SwissProt Accessions	Q7Z3E2, Q2M2V6, Q6NS91, Q7RTP1, Q8N117, Q8N3G3, Q8N6C2, Q9NWA3	Gene names	C10orf118
Domain Architecture	No domain graphic available
Description	Protein C10orf118 (CTCL tumor antigen HD-CL-01/L14-2).

MRCKB_MOUSE
NC score	0.053157 (rank : 189)	θ value	θ > 10 (rank : 230)
Query Neighborhood Hits	185	Target Neighborhood Hits	2180	Shared Neighborhood Hits	122
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

DP13A_MOUSE
NC score	0.052905 (rank : 190)	θ value	θ > 10 (rank : 217)
Query Neighborhood Hits	185	Target Neighborhood Hits	96	Shared Neighborhood Hits	16
SwissProt Accessions	Q8K3H0, Q3UJP7, Q69ZJ9, Q8BWZ8, Q8VCJ8, Q9CUW4	Gene names	Appl1, Dip13a, Kiaa1428
Domain Architecture	No domain graphic available
Description	DCC-interacting protein 13 alpha (Dip13 alpha) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 1).

REST_MOUSE
NC score	0.052837 (rank : 191)	θ value	θ > 10 (rank : 275)
Query Neighborhood Hits	185	Target Neighborhood Hits	1506	Shared Neighborhood Hits	84
SwissProt Accessions	Q922J3, Q571L7	Gene names	Rsn, Kiaa4046
Domain Architecture	No domain graphic available
Description	Restin.

TPR_HUMAN
NC score	0.052627 (rank : 192)	θ value	2.36792 (rank : 126)
Query Neighborhood Hits	185	Target Neighborhood Hits	1921	Shared Neighborhood Hits	90
SwissProt Accessions	P12270, Q15655	Gene names	TPR
Domain Architecture
Description	Nucleoprotein TPR.

CCD46_HUMAN
NC score	0.052597 (rank : 193)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	185	Target Neighborhood Hits	1430	Shared Neighborhood Hits	85
SwissProt Accessions	Q8N8E3, Q6PIB5, Q8NCR4, Q8NFR4	Gene names	CCDC46
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 46.

TPM4_HUMAN
NC score	0.052585 (rank : 194)	θ value	θ > 10 (rank : 290)
Query Neighborhood Hits	185	Target Neighborhood Hits	525	Shared Neighborhood Hits	57
SwissProt Accessions	P67936, P07226, Q15659, Q9BU85, Q9H8Q3	Gene names	TPM4
Domain Architecture	No domain graphic available
Description	Tropomyosin alpha-4 chain (Tropomyosin-4) (TM30p1).

CING_HUMAN
NC score	0.052545 (rank : 195)	θ value	0.813845 (rank : 91)
Query Neighborhood Hits	185	Target Neighborhood Hits	1275	Shared Neighborhood Hits	75
SwissProt Accessions	Q9P2M7, Q5T386, Q9NR25	Gene names	CGN, KIAA1319
Domain Architecture
Description	Cingulin.

TPM4_MOUSE
NC score	0.052222 (rank : 196)	θ value	θ > 10 (rank : 291)
Query Neighborhood Hits	185	Target Neighborhood Hits	703	Shared Neighborhood Hits	62
SwissProt Accessions	Q6IRU2	Gene names	Tpm4
Domain Architecture	No domain graphic available
Description	Tropomyosin alpha-4 chain (Tropomyosin-4).

MRCKA_HUMAN
NC score	0.051964 (rank : 197)	θ value	8.99809 (rank : 179)
Query Neighborhood Hits	185	Target Neighborhood Hits	1999	Shared Neighborhood Hits	115
SwissProt Accessions	Q5VT25, Q59GZ1, Q5H9N9, Q5T797, Q5VT26, Q5VT27, Q86XX2, Q86XX3, Q99646	Gene names	CDC42BPA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42- binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) (DMPK-like alpha).

CROCC_MOUSE
NC score	0.051947 (rank : 198)	θ value	6.88961 (rank : 165)
Query Neighborhood Hits	185	Target Neighborhood Hits	1460	Shared Neighborhood Hits	82
SwissProt Accessions	Q8CJ40, Q7TQL2, Q80U01, Q8R0B9	Gene names	Crocc, Kiaa0445
Domain Architecture	No domain graphic available
Description	Rootletin (Ciliary rootlet coiled-coil protein).

VINEX_HUMAN
NC score	0.051943 (rank : 199)	θ value	θ > 10 (rank : 301)
Query Neighborhood Hits	185	Target Neighborhood Hits	270	Shared Neighborhood Hits	20
SwissProt Accessions	O60504, Q9UQE4	Gene names	SORBS3, SCAM1
Domain Architecture
Description	Vinexin (Sorbin and SH3 domain-containing protein 3) (SH3-containing adapter molecule 1) (SCAM-1).

PIBF1_HUMAN
NC score	0.051940 (rank : 200)	θ value	θ > 10 (rank : 267)
Query Neighborhood Hits	185	Target Neighborhood Hits	1041	Shared Neighborhood Hits	76
SwissProt Accessions	Q8WXW3, O95664, Q6U9V2, Q6UG50, Q86V07, Q96SF4	Gene names	PIBF1, C13orf24, PIBF
Domain Architecture
Description	Progesterone-induced-blocking factor 1.

KPCD3_HUMAN
NC score	0.051830 (rank : 201)	θ value	0.21417 (rank : 73)
Query Neighborhood Hits	185	Target Neighborhood Hits	895	Shared Neighborhood Hits	50
SwissProt Accessions	O94806	Gene names	PRKD3, EPK2, PRKCN
Domain Architecture
Description	Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) (nPKC-nu) (Protein kinase EPK2).

ATCAY_MOUSE
NC score	0.051752 (rank : 202)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	185	Target Neighborhood Hits	19	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BHE3, Q3TR94	Gene names	Atcay
Domain Architecture
Description	Caytaxin.

SH3K1_MOUSE
NC score	0.051739 (rank : 203)	θ value	θ > 10 (rank : 276)
Query Neighborhood Hits	185	Target Neighborhood Hits	332	Shared Neighborhood Hits	25
SwissProt Accessions	Q8R550, Q8CAL8, Q8CEF6, Q8R545, Q8R546, Q8R547, Q8R548, Q8R549, Q8R551, Q9CTQ9, Q9DC14, Q9JKC3	Gene names	Sh3kbp1, Ruk, Seta
Domain Architecture
Description	SH3-domain kinase-binding protein 1 (SH3-containing, expressed in tumorigenic astrocytes) (Regulator of ubiquitous kinase) (Ruk).

FLIP1_HUMAN
NC score	0.051710 (rank : 204)	θ value	1.81305 (rank : 112)
Query Neighborhood Hits	185	Target Neighborhood Hits	1405	Shared Neighborhood Hits	76
SwissProt Accessions	Q7Z7B0, Q5VUL6, Q86TC3, Q8N8B9, Q96SK6, Q9NVI8, Q9ULE5	Gene names	FILIP1, KIAA1275
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

CN145_HUMAN
NC score	0.051634 (rank : 205)	θ value	θ > 10 (rank : 205)
Query Neighborhood Hits	185	Target Neighborhood Hits	1196	Shared Neighborhood Hits	79
SwissProt Accessions	Q6ZU80, Q96ML4	Gene names	C14orf145
Domain Architecture	No domain graphic available
Description	Protein C14orf145.

CTRO_MOUSE
NC score	0.051576 (rank : 206)	θ value	0.00509761 (rank : 61)
Query Neighborhood Hits	185	Target Neighborhood Hits	2344	Shared Neighborhood Hits	118
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

NIN_HUMAN
NC score	0.051568 (rank : 207)	θ value	θ > 10 (rank : 262)
Query Neighborhood Hits	185	Target Neighborhood Hits	1416	Shared Neighborhood Hits	83
SwissProt Accessions	Q8N4C6, Q6P0P6, Q9BWU6, Q9C012, Q9C013, Q9C014, Q9H5I6, Q9HAT7, Q9HBY5, Q9HCK7, Q9UH61	Gene names	NIN, KIAA1565
Domain Architecture	No domain graphic available
Description	Ninein (hNinein) (Glycogen synthase kinase 3 beta-interacting protein) (GSK3B-interacting protein).

GOGB1_HUMAN
NC score	0.051565 (rank : 208)	θ value	θ > 10 (rank : 221)
Query Neighborhood Hits	185	Target Neighborhood Hits	2297	Shared Neighborhood Hits	94
SwissProt Accessions	Q14789, Q14398	Gene names	GOLGB1
Domain Architecture
Description	Golgin subfamily B member 1 (Giantin) (Macrogolgin) (372 kDa Golgi complex-associated protein) (GCP372).

CCD46_MOUSE
NC score	0.051557 (rank : 209)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	185	Target Neighborhood Hits	1405	Shared Neighborhood Hits	84
SwissProt Accessions	Q5PR68, Q80ZN6, Q99JS4, Q9D9T1	Gene names	Ccdc46
Domain Architecture	No domain graphic available
Description	Coiled coil domain-containing protein 46.

RAD50_MOUSE
NC score	0.051464 (rank : 210)	θ value	θ > 10 (rank : 271)
Query Neighborhood Hits	185	Target Neighborhood Hits	1366	Shared Neighborhood Hits	82
SwissProt Accessions	P70388, Q6PEB0, Q8C2T7, Q9CU59	Gene names	Rad50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (mRad50).

ARFG3_MOUSE
NC score	0.051392 (rank : 211)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	185	Target Neighborhood Hits	80	Shared Neighborhood Hits	7
SwissProt Accessions	Q9D8S3, Q99KN8	Gene names	Arfgap3
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3).

GOGA4_HUMAN
NC score	0.051372 (rank : 212)	θ value	1.38821 (rank : 105)
Query Neighborhood Hits	185	Target Neighborhood Hits	2034	Shared Neighborhood Hits	87
SwissProt Accessions	Q13439, Q13270, Q13654, Q14436	Gene names	GOLGA4
Domain Architecture
Description	Golgin subfamily A member 4 (Trans-Golgi p230) (256 kDa golgin) (Golgin-245) (Protein 72.1).

KPCD1_HUMAN
NC score	0.051325 (rank : 213)	θ value	0.0193708 (rank : 66)
Query Neighborhood Hits	185	Target Neighborhood Hits	901	Shared Neighborhood Hits	50
SwissProt Accessions	Q15139	Gene names	PRKD1, PKD, PKD1, PRKCM
Domain Architecture
Description	Serine/threonine-protein kinase D1 (EC 2.7.11.13) (nPKC-D1) (Protein kinase D) (Protein kinase C mu type) (nPKC-mu).

ATCAY_HUMAN
NC score	0.051324 (rank : 214)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	185	Target Neighborhood Hits	18	Shared Neighborhood Hits	4
SwissProt Accessions	Q86WG3, Q8NAQ2, Q8TAQ3, Q96HC6, Q96JF5	Gene names	ATCAY, KIAA1872
Domain Architecture
Description	Caytaxin (Ataxia Cayman type protein) (BNIP-H).

RAD50_HUMAN
NC score	0.051116 (rank : 215)	θ value	θ > 10 (rank : 270)
Query Neighborhood Hits	185	Target Neighborhood Hits	1317	Shared Neighborhood Hits	79
SwissProt Accessions	Q92878, O43254, Q6GMT7, Q6P5X3, Q9UP86	Gene names	RAD50
Domain Architecture	No domain graphic available
Description	DNA repair protein RAD50 (EC 3.6.-.-) (hRAD50).

SRBS1_HUMAN
NC score	0.051067 (rank : 216)	θ value	θ > 10 (rank : 281)
Query Neighborhood Hits	185	Target Neighborhood Hits	396	Shared Neighborhood Hits	24
SwissProt Accessions	Q9BX66, Q7LBE5, Q8IVK0, Q8IVQ4, Q96KF3, Q96KF4, Q9BX64, Q9BX65, Q9P2Q0, Q9UFT2, Q9UHN7, Q9Y338	Gene names	SORBS1, KIAA1296, SH3D5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

KPCD1_MOUSE
NC score	0.050971 (rank : 217)	θ value	0.0330416 (rank : 67)
Query Neighborhood Hits	185	Target Neighborhood Hits	891	Shared Neighborhood Hits	50
SwissProt Accessions	Q62101	Gene names	Prkd1, Pkcm, Pkd, Prkcm
Domain Architecture
Description	Serine/threonine-protein kinase D1 (EC 2.7.11.13) (nPKC-D1) (Protein kinase D) (Protein kinase C mu type) (nPKC-mu).

OPTN_MOUSE
NC score	0.050954 (rank : 218)	θ value	6.88961 (rank : 169)
Query Neighborhood Hits	185	Target Neighborhood Hits	1120	Shared Neighborhood Hits	75
SwissProt Accessions	Q8K3K8	Gene names	Optn
Domain Architecture	No domain graphic available
Description	Optineurin.

TEX9_HUMAN
NC score	0.050846 (rank : 219)	θ value	3.0926 (rank : 138)
Query Neighborhood Hits	185	Target Neighborhood Hits	541	Shared Neighborhood Hits	62
SwissProt Accessions	Q8N6V9	Gene names	TEX9
Domain Architecture	No domain graphic available
Description	Testis-expressed sequence 9 protein.

HOOK3_HUMAN
NC score	0.050822 (rank : 220)	θ value	θ > 10 (rank : 227)
Query Neighborhood Hits	185	Target Neighborhood Hits	1070	Shared Neighborhood Hits	75
SwissProt Accessions	Q86VS8, Q8NBH0, Q9BY13	Gene names	HOOK3
Domain Architecture
Description	Hook homolog 3 (hHK3).

CP250_HUMAN
NC score	0.050791 (rank : 221)	θ value	θ > 10 (rank : 206)
Query Neighborhood Hits	185	Target Neighborhood Hits	1805	Shared Neighborhood Hits	85
SwissProt Accessions	Q9BV73, O14812, O60588, Q9H450	Gene names	CEP250, CEP2, CNAP1
Domain Architecture
Description	Centrosome-associated protein CEP250 (Centrosomal protein 2) (Centrosomal Nek2-associated protein 1) (C-Nap1).

ARFG3_HUMAN
NC score	0.050764 (rank : 222)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	185	Target Neighborhood Hits	56	Shared Neighborhood Hits	6
SwissProt Accessions	Q9NP61, Q9BSC6, Q9H9J0, Q9NT10, Q9NUP5, Q9Y4V3, Q9Y4V4	Gene names	ARFGAP3, ARFGAP1
Domain Architecture
Description	ADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3).

KPCD3_MOUSE
NC score	0.050699 (rank : 223)	θ value	0.279714 (rank : 77)
Query Neighborhood Hits	185	Target Neighborhood Hits	901	Shared Neighborhood Hits	50
SwissProt Accessions	Q8K1Y2	Gene names	Prkd3, Prkcn
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) (nPKC-nu).

KMHN1_HUMAN
NC score	0.050560 (rank : 224)	θ value	θ > 10 (rank : 229)
Query Neighborhood Hits	185	Target Neighborhood Hits	950	Shared Neighborhood Hits	73
SwissProt Accessions	Q8TBZ0, Q86YI9, Q8N7W0	Gene names	KMHN1
Domain Architecture	No domain graphic available
Description	Cancer/testis antigen KM-HN-1.

SRBS1_MOUSE
NC score	0.050522 (rank : 225)	θ value	θ > 10 (rank : 282)
Query Neighborhood Hits	185	Target Neighborhood Hits	409	Shared Neighborhood Hits	25
SwissProt Accessions	Q62417, Q80TF8, Q8BZI3, Q8K3Y2, Q921F8, Q9Z0Z8, Q9Z0Z9	Gene names	Sorbs1, Kiaa1296, Sh3d5
Domain Architecture	No domain graphic available
Description	Sorbin and SH3 domain-containing protein 1 (Ponsin) (c-Cbl-associated protein) (CAP) (SH3 domain protein 5) (SH3P12).

GCC2_HUMAN
NC score	0.050502 (rank : 226)	θ value	θ > 10 (rank : 220)
Query Neighborhood Hits	185	Target Neighborhood Hits	1558	Shared Neighborhood Hits	85
SwissProt Accessions	Q8IWJ2, O15045, Q8TDH3, Q9H2G8	Gene names	GCC2, KIAA0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185) (CTCL tumor antigen se1-1) (CLL-associated antigen KW- 11) (NY-REN-53 antigen).

CK5P2_HUMAN
NC score	0.050489 (rank : 227)	θ value	θ > 10 (rank : 204)
Query Neighborhood Hits	185	Target Neighborhood Hits	1433	Shared Neighborhood Hits	85
SwissProt Accessions	Q96SN8, Q7Z3L4, Q7Z3U1, Q7Z7I6, Q9BSW0, Q9H6J6, Q9HCD9, Q9NV90, Q9UIW9	Gene names	CDK5RAP2, CEP215, KIAA1633
Domain Architecture
Description	CDK5 regulatory subunit-associated protein 2 (CDK5 activator-binding protein C48) (Centrosome-associated protein 215).

DDFL1_MOUSE
NC score	0.050470 (rank : 228)	θ value	θ > 10 (rank : 213)
Query Neighborhood Hits	185	Target Neighborhood Hits	324	Shared Neighborhood Hits	11
SwissProt Accessions	Q5U464	Gene names	Ddefl1
Domain Architecture	No domain graphic available
Description	Development and differentiation-enhancing factor-like 1.

SYCP1_MOUSE
NC score	0.050304 (rank : 229)	θ value	θ > 10 (rank : 287)
Query Neighborhood Hits	185	Target Neighborhood Hits	1456	Shared Neighborhood Hits	80
SwissProt Accessions	Q62209, O09205, P70192, Q62329	Gene names	Sycp1, Scp1
Domain Architecture
Description	Synaptonemal complex protein 1 (SCP-1).

RBP24_HUMAN
NC score	0.050291 (rank : 230)	θ value	θ > 10 (rank : 274)
Query Neighborhood Hits	185	Target Neighborhood Hits	1559	Shared Neighborhood Hits	85
SwissProt Accessions	Q4ZG46	Gene names	RANBP2L4
Domain Architecture	No domain graphic available
Description	Ran-binding protein 2-like 4 (RanBP2L4).

BNIPL_HUMAN
NC score	0.050197 (rank : 231)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	185	Target Neighborhood Hits	40	Shared Neighborhood Hits	4
SwissProt Accessions	Q7Z465, Q6DK43, Q8TCY7, Q8WYG2	Gene names	BNIPL
Domain Architecture	No domain graphic available
Description	Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein.

BNIPL_MOUSE
NC score	0.050192 (rank : 232)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	185	Target Neighborhood Hits	13	Shared Neighborhood Hits	3
SwissProt Accessions	Q99JU7, Q923E3	Gene names	Bnipl
Domain Architecture	No domain graphic available
Description	Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein.

KPCD2_HUMAN
NC score	0.049586 (rank : 233)	θ value	0.0113563 (rank : 62)
Query Neighborhood Hits	185	Target Neighborhood Hits	910	Shared Neighborhood Hits	50
SwissProt Accessions	Q9BZL6, Q8TB08, Q9P0T6, Q9Y3X8	Gene names	PRKD2, PKD2
Domain Architecture
Description	Serine/threonine-protein kinase D2 (EC 2.7.11.13) (nPKC-D2).

GCC2_MOUSE
NC score	0.049275 (rank : 234)	θ value	5.27518 (rank : 160)
Query Neighborhood Hits	185	Target Neighborhood Hits	1619	Shared Neighborhood Hits	81
SwissProt Accessions	Q8CHG3, Q8BR44, Q8R2Q5, Q9CT45	Gene names	Gcc2, Kiaa0336
Domain Architecture
Description	GRIP and coiled-coil domain-containing protein 2 (Golgi coiled coil protein GCC185).

AKAP9_HUMAN
NC score	0.048869 (rank : 235)	θ value	4.03905 (rank : 140)
Query Neighborhood Hits	185	Target Neighborhood Hits	1710	Shared Neighborhood Hits	84
SwissProt Accessions	Q99996, O14869, O43355, O94895, Q9UQH3, Q9UQQ4, Q9Y6B8, Q9Y6Y2	Gene names	AKAP9, AKAP350, AKAP450, KIAA0803
Domain Architecture
Description	A-kinase anchor protein 9 (Protein kinase A-anchoring protein 9) (PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (AKAP 120-like protein) (Protein hyperion) (Protein yotiao) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP).

BPAEA_MOUSE
NC score	0.048138 (rank : 236)	θ value	0.813845 (rank : 90)
Query Neighborhood Hits	185	Target Neighborhood Hits	1480	Shared Neighborhood Hits	75
SwissProt Accessions	Q91ZU8, Q8K5D4	Gene names	Dst, Bpag1
Domain Architecture
Description	Bullous pemphigoid antigen 1, isoform 5 (BPA) (Hemidesmosomal plaque protein) (Dystonia musculorum protein) (Dystonin).

CTRO_HUMAN
NC score	0.047814 (rank : 237)	θ value	0.0148317 (rank : 63)
Query Neighborhood Hits	185	Target Neighborhood Hits	2092	Shared Neighborhood Hits	110
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

TJAP1_MOUSE
NC score	0.046319 (rank : 238)	θ value	0.279714 (rank : 81)
Query Neighborhood Hits	185	Target Neighborhood Hits	295	Shared Neighborhood Hits	45
SwissProt Accessions	Q9DCD5, Q8CFL7, Q8R5I2	Gene names	Tjap1, Pilt, Tjp4
Domain Architecture	No domain graphic available
Description	Tight junction-associated protein 1 (Tight junction protein 4) (Protein incorporated later into tight junctions).

IFT81_HUMAN
NC score	0.046058 (rank : 239)	θ value	4.03905 (rank : 145)
Query Neighborhood Hits	185	Target Neighborhood Hits	893	Shared Neighborhood Hits	72
SwissProt Accessions	Q8WYA0, Q8NB51, Q9BSV2, Q9UNY8	Gene names	IFT81, CDV1
Domain Architecture	No domain graphic available
Description	Intraflagellar transport 81 (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1 protein).

PEPL_HUMAN
NC score	0.045356 (rank : 240)	θ value	1.06291 (rank : 100)
Query Neighborhood Hits	185	Target Neighborhood Hits	1141	Shared Neighborhood Hits	74
SwissProt Accessions	O60437, O60314, O60454	Gene names	PPL, KIAA0568
Domain Architecture
Description	Periplakin (195 kDa cornified envelope precursor protein) (190 kDa paraneoplastic pemphigus antigen).

FLIP1_MOUSE
NC score	0.045343 (rank : 241)	θ value	4.03905 (rank : 144)
Query Neighborhood Hits	185	Target Neighborhood Hits	1176	Shared Neighborhood Hits	72
SwissProt Accessions	Q9CS72	Gene names	Filip1
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

GRAP1_MOUSE
NC score	0.045218 (rank : 242)	θ value	1.81305 (rank : 113)
Query Neighborhood Hits	185	Target Neighborhood Hits	1234	Shared Neighborhood Hits	75
SwissProt Accessions	Q8VD04, O35693, Q3T9C3, Q69ZP9	Gene names	Gripap1, DXImx47e, Kiaa1167
Domain Architecture	No domain graphic available
Description	GRIP1-associated protein 1 (GRASP-1) (HCMV-interacting protein).

DGKA_HUMAN
NC score	0.044632 (rank : 243)	θ value	4.03905 (rank : 143)
Query Neighborhood Hits	185	Target Neighborhood Hits	151	Shared Neighborhood Hits	38
SwissProt Accessions	P23743, O75481, O75482, O75483	Gene names	DGKA, DAGK, DAGK1
Domain Architecture
Description	Diacylglycerol kinase alpha (EC 2.7.1.107) (Diglyceride kinase alpha) (DGK-alpha) (DAG kinase alpha) (80 kDa diacylglycerol kinase).

ROCK1_MOUSE
NC score	0.043809 (rank : 244)	θ value	2.36792 (rank : 124)
Query Neighborhood Hits	185	Target Neighborhood Hits	2126	Shared Neighborhood Hits	112
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

C102B_HUMAN
NC score	0.043577 (rank : 245)	θ value	8.99809 (rank : 172)
Query Neighborhood Hits	185	Target Neighborhood Hits	542	Shared Neighborhood Hits	58
SwissProt Accessions	Q68D86, Q7Z467, Q8NDK7, Q9H5C1	Gene names	CCDC102B, C18orf14
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 102B.

KPCD_HUMAN
NC score	0.042531 (rank : 246)	θ value	0.813845 (rank : 92)
Query Neighborhood Hits	185	Target Neighborhood Hits	900	Shared Neighborhood Hits	50
SwissProt Accessions	Q05655, Q15144	Gene names	PRKCD
Domain Architecture
Description	Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta).

ROCK1_HUMAN
NC score	0.042090 (rank : 247)	θ value	3.0926 (rank : 136)
Query Neighborhood Hits	185	Target Neighborhood Hits	2000	Shared Neighborhood Hits	109
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).

KPCD_MOUSE
NC score	0.041585 (rank : 248)	θ value	1.81305 (rank : 114)
Query Neighborhood Hits	185	Target Neighborhood Hits	888	Shared Neighborhood Hits	50
SwissProt Accessions	P28867, Q91V85, Q9Z333	Gene names	Prkcd, Pkcd
Domain Architecture
Description	Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta).

KPCA_HUMAN
NC score	0.039517 (rank : 249)	θ value	2.36792 (rank : 119)
Query Neighborhood Hits	185	Target Neighborhood Hits	1070	Shared Neighborhood Hits	55
SwissProt Accessions	P17252, Q15137, Q96RE4	Gene names	PRKCA, PKCA, PRKACA
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

UACA_HUMAN
NC score	0.039238 (rank : 250)	θ value	1.06291 (rank : 101)
Query Neighborhood Hits	185	Target Neighborhood Hits	1622	Shared Neighborhood Hits	78
SwissProt Accessions	Q9BZF9, Q8N3B8, Q9HCL1, Q9NWC6	Gene names	UACA, KIAA1561
Domain Architecture	No domain graphic available
Description	Uveal autoantigen with coiled-coil domains and ankyrin repeats protein.

KPCB_MOUSE
NC score	0.039125 (rank : 251)	θ value	4.03905 (rank : 148)
Query Neighborhood Hits	185	Target Neighborhood Hits	1117	Shared Neighborhood Hits	52
SwissProt Accessions	P68404, P04410, P04411	Gene names	Prkcb1, Pkcb, Prkcb
Domain Architecture	No domain graphic available
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

KPCB_HUMAN
NC score	0.039091 (rank : 252)	θ value	4.03905 (rank : 147)
Query Neighborhood Hits	185	Target Neighborhood Hits	1121	Shared Neighborhood Hits	52
SwissProt Accessions	P05771, O43744, P05127, Q15138, Q93060, Q9UE49, Q9UE50, Q9UEH8, Q9UJ30, Q9UJ33	Gene names	PRKCB1, PKCB, PRKCB
Domain Architecture
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

KPCA_MOUSE
NC score	0.038580 (rank : 253)	θ value	2.36792 (rank : 120)
Query Neighborhood Hits	185	Target Neighborhood Hits	1067	Shared Neighborhood Hits	55
SwissProt Accessions	P20444	Gene names	Prkca, Pkca
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

KPCG_MOUSE
NC score	0.037476 (rank : 254)	θ value	8.99809 (rank : 176)
Query Neighborhood Hits	185	Target Neighborhood Hits	1123	Shared Neighborhood Hits	52
SwissProt Accessions	P63318, P05697	Gene names	Prkcg, Pkcc, Pkcg, Prkcc
Domain Architecture	No domain graphic available
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

KPCG_HUMAN
NC score	0.037455 (rank : 255)	θ value	8.99809 (rank : 175)
Query Neighborhood Hits	185	Target Neighborhood Hits	1126	Shared Neighborhood Hits	52
SwissProt Accessions	P05129	Gene names	PRKCG, PKCG
Domain Architecture
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

MACF4_HUMAN
NC score	0.036412 (rank : 256)	θ value	4.03905 (rank : 152)
Query Neighborhood Hits	185	Target Neighborhood Hits	1321	Shared Neighborhood Hits	76
SwissProt Accessions	Q96PK2, Q8WXY1	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoform 4.

RADI_MOUSE
NC score	0.036278 (rank : 257)	θ value	3.0926 (rank : 132)
Query Neighborhood Hits	185	Target Neighborhood Hits	773	Shared Neighborhood Hits	68
SwissProt Accessions	P26043, Q9QW27	Gene names	Rdx
Domain Architecture
Description	Radixin (ESP10).

LIPB1_MOUSE
NC score	0.036249 (rank : 258)	θ value	8.99809 (rank : 178)
Query Neighborhood Hits	185	Target Neighborhood Hits	727	Shared Neighborhood Hits	66
SwissProt Accessions	Q8C8U0, Q69ZN5, Q6GQV3, Q80VB4, Q9CUT7	Gene names	Ppfibp1, Kiaa1230
Domain Architecture
Description	Liprin-beta-1 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1) (PTPRF-interacting protein-binding protein 1).

BAT2_HUMAN
NC score	0.035775 (rank : 259)	θ value	1.06291 (rank : 97)
Query Neighborhood Hits	185	Target Neighborhood Hits	931	Shared Neighborhood Hits	21
SwissProt Accessions	P48634, O95875, Q5SQ29, Q5SQ30, Q5ST84, Q5STX6, Q5STX7, Q68DW9, Q6P9P7, Q6PIN1, Q96QC6	Gene names	BAT2, G2
Domain Architecture
Description	Large proline-rich protein BAT2 (HLA-B-associated transcript 2).

MACF1_HUMAN
NC score	0.035712 (rank : 260)	θ value	4.03905 (rank : 151)
Query Neighborhood Hits	185	Target Neighborhood Hits	1341	Shared Neighborhood Hits	78
SwissProt Accessions	Q9UPN3, O75053, Q5VW20, Q8WXY2, Q9H540, Q9UKP0, Q9ULG9	Gene names	MACF1, ABP620, ACF7, KIAA0465, KIAA1251
Domain Architecture
Description	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha) (620 kDa actin-binding protein) (ABP620).

PLEC1_HUMAN
NC score	0.035441 (rank : 261)	θ value	8.99809 (rank : 184)
Query Neighborhood Hits	185	Target Neighborhood Hits	1326	Shared Neighborhood Hits	70
SwissProt Accessions	Q15149, Q15148, Q16640	Gene names	PLEC1
Domain Architecture
Description	Plectin-1 (PLTN) (PCN) (Hemidesmosomal protein 1) (HD1).

KPCZ_HUMAN
NC score	0.034524 (rank : 262)	θ value	3.0926 (rank : 129)
Query Neighborhood Hits	185	Target Neighborhood Hits	884	Shared Neighborhood Hits	48
SwissProt Accessions	Q05513, Q15207, Q5SYT5, Q969S4	Gene names	PRKCZ, PKC2
Domain Architecture
Description	Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta).

KSR2_HUMAN
NC score	0.034197 (rank : 263)	θ value	0.0431538 (rank : 68)
Query Neighborhood Hits	185	Target Neighborhood Hits	920	Shared Neighborhood Hits	45
SwissProt Accessions	Q6VAB6, Q8N775	Gene names	KSR2
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-2 (hKSR2).

KPCI_MOUSE
NC score	0.033762 (rank : 264)	θ value	1.81305 (rank : 115)
Query Neighborhood Hits	185	Target Neighborhood Hits	888	Shared Neighborhood Hits	50
SwissProt Accessions	Q62074	Gene names	Prkci, Pkcl
Domain Architecture
Description	Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota) (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota).

KPCI_HUMAN
NC score	0.033518 (rank : 265)	θ value	2.36792 (rank : 121)
Query Neighborhood Hits	185	Target Neighborhood Hits	885	Shared Neighborhood Hits	50
SwissProt Accessions	P41743, Q8WW06	Gene names	PRKCI, DXS1179E
Domain Architecture
Description	Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota) (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota) (PRKC-lambda/iota).

KPCZ_MOUSE
NC score	0.033195 (rank : 266)	θ value	5.27518 (rank : 161)
Query Neighborhood Hits	185	Target Neighborhood Hits	882	Shared Neighborhood Hits	47
SwissProt Accessions	Q02956	Gene names	Prkcz, Pkcz
Domain Architecture
Description	Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta).

SFR17_HUMAN
NC score	0.032832 (rank : 267)	θ value	1.38821 (rank : 108)
Query Neighborhood Hits	185	Target Neighborhood Hits	325	Shared Neighborhood Hits	31
SwissProt Accessions	Q8TF01, Q5T064, Q6P2B4, Q6P2N4, Q6PJ93, Q6PK36, Q7Z640, Q8TF00, Q96K10, Q96SM5, Q9P076, Q9P0C0, Q9Y4N3	Gene names	SRRP130, C6orf111
Domain Architecture	No domain graphic available
Description	Splicing factor, arginine/serine-rich 130 (Serine-arginine-rich- splicing regulatory protein 130) (SRrp130) (SR-rich protein) (SR- related protein).

MOES_HUMAN
NC score	0.032051 (rank : 268)	θ value	1.38821 (rank : 106)
Query Neighborhood Hits	185	Target Neighborhood Hits	892	Shared Neighborhood Hits	68
SwissProt Accessions	P26038	Gene names	MSN
Domain Architecture
Description	Moesin (Membrane-organizing extension spike protein).

AKA12_HUMAN
NC score	0.031050 (rank : 269)	θ value	6.88961 (rank : 163)
Query Neighborhood Hits	185	Target Neighborhood Hits	825	Shared Neighborhood Hits	46
SwissProt Accessions	Q02952, O00310, O00498, Q99970	Gene names	AKAP12, AKAP250
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 12 (A-kinase anchor protein 250 kDa) (AKAP 250) (Myasthenia gravis autoantigen gravin).

PRC1_MOUSE
NC score	0.029240 (rank : 270)	θ value	5.27518 (rank : 162)
Query Neighborhood Hits	185	Target Neighborhood Hits	382	Shared Neighborhood Hits	47
SwissProt Accessions	Q99K43, Q8CE25	Gene names	Prc1
Domain Architecture	No domain graphic available
Description	Protein regulator of cytokinesis 1.

ARAF_MOUSE
NC score	0.027554 (rank : 271)	θ value	3.0926 (rank : 128)
Query Neighborhood Hits	185	Target Neighborhood Hits	874	Shared Neighborhood Hits	42
SwissProt Accessions	P04627, Q99J44, Q9CTT5, Q9D6R6, Q9DBU7	Gene names	Araf, A-raf, Araf1
Domain Architecture
Description	A-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1).

DPOA2_HUMAN
NC score	0.027494 (rank : 272)	θ value	0.62314 (rank : 86)
Query Neighborhood Hits	185	Target Neighborhood Hits	10	Shared Neighborhood Hits	2
SwissProt Accessions	Q14181, Q9BPV3	Gene names	POLA2
Domain Architecture
Description	DNA polymerase subunit alpha B (DNA polymerase alpha 70 kDa subunit).

RAF1_HUMAN
NC score	0.027357 (rank : 273)	θ value	3.0926 (rank : 133)
Query Neighborhood Hits	185	Target Neighborhood Hits	886	Shared Neighborhood Hits	43
SwissProt Accessions	P04049	Gene names	RAF1, RAF
Domain Architecture
Description	RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf- 1) (C-RAF) (cRaf).

ARAF_HUMAN
NC score	0.027349 (rank : 274)	θ value	3.0926 (rank : 127)
Query Neighborhood Hits	185	Target Neighborhood Hits	924	Shared Neighborhood Hits	43
SwissProt Accessions	P10398, P07557, Q5H9B3	Gene names	ARAF, ARAF1, PKS, PKS2
Domain Architecture
Description	A-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (A- raf-1) (Proto-oncogene Pks).

RABX5_MOUSE
NC score	0.027322 (rank : 275)	θ value	0.47712 (rank : 84)
Query Neighborhood Hits	185	Target Neighborhood Hits	39	Shared Neighborhood Hits	2
SwissProt Accessions	Q9JM13, Q3UIW0	Gene names	Rabgef1, Rabex5
Domain Architecture
Description	Rab5 GDP/GTP exchange factor (Rabex-5).

LAMA4_HUMAN
NC score	0.026988 (rank : 276)	θ value	4.03905 (rank : 150)
Query Neighborhood Hits	185	Target Neighborhood Hits	708	Shared Neighborhood Hits	58
SwissProt Accessions	Q16363, Q14735, Q15335, Q4LE44, Q5SZG8, Q9UE18, Q9UJN9	Gene names	LAMA4
Domain Architecture
Description	Laminin alpha-4 chain precursor.

RAF1_MOUSE
NC score	0.026983 (rank : 277)	θ value	3.0926 (rank : 134)
Query Neighborhood Hits	185	Target Neighborhood Hits	886	Shared Neighborhood Hits	43
SwissProt Accessions	Q99N57, Q91WH1	Gene names	Raf1, Craf
Domain Architecture
Description	RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf- 1) (C-RAF) (cRaf).

KSR1_HUMAN
NC score	0.026647 (rank : 278)	θ value	0.813845 (rank : 93)
Query Neighborhood Hits	185	Target Neighborhood Hits	867	Shared Neighborhood Hits	43
SwissProt Accessions	Q8IVT5, Q13476	Gene names	KSR1, KSR
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-1 (Kinase suppressor of ras).

BRAF1_HUMAN
NC score	0.025638 (rank : 279)	θ value	5.27518 (rank : 155)
Query Neighborhood Hits	185	Target Neighborhood Hits	883	Shared Neighborhood Hits	43
SwissProt Accessions	P15056, Q13878, Q9Y6T3	Gene names	BRAF, BRAF1, RAFB1
Domain Architecture
Description	B-Raf proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (p94) (v-Raf murine sarcoma viral oncogene homolog B1).

KSR1_MOUSE
NC score	0.025623 (rank : 280)	θ value	4.03905 (rank : 149)
Query Neighborhood Hits	185	Target Neighborhood Hits	870	Shared Neighborhood Hits	40
SwissProt Accessions	Q61097, Q61648, Q78DX8	Gene names	Ksr1, Ksr
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-1 (Kinase suppressor of ras) (mKSR1) (Hb protein).

KI21A_HUMAN
NC score	0.024252 (rank : 281)	θ value	8.99809 (rank : 174)
Query Neighborhood Hits	185	Target Neighborhood Hits	1543	Shared Neighborhood Hits	80
SwissProt Accessions	Q7Z4S6, Q6UKL9, Q7Z668, Q86WZ5, Q8IVZ8, Q9C0F5, Q9NXU4, Q9Y590	Gene names	KIF21A, KIAA1708, KIF2
Domain Architecture	No domain graphic available
Description	Kinesin family member 21A (Kinesin-like protein KIF2) (NY-REN-62 antigen).

RN168_MOUSE
NC score	0.022678 (rank : 282)	θ value	3.0926 (rank : 135)
Query Neighborhood Hits	185	Target Neighborhood Hits	440	Shared Neighborhood Hits	34
SwissProt Accessions	Q80XJ2	Gene names	Rnf168
Domain Architecture	No domain graphic available
Description	RING finger protein 168.

KS6C1_MOUSE
NC score	0.019943 (rank : 283)	θ value	3.0926 (rank : 130)
Query Neighborhood Hits	185	Target Neighborhood Hits	700	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BLK9, Q3UDY3, Q6PDY4, Q8BMQ5, Q8BX49	Gene names	Rps6kc1
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase delta-1 (EC 2.7.11.1) (52 kDa ribosomal protein S6 kinase).

CTR9_HUMAN
NC score	0.019690 (rank : 284)	θ value	4.03905 (rank : 141)
Query Neighborhood Hits	185	Target Neighborhood Hits	383	Shared Neighborhood Hits	24
SwissProt Accessions	Q6PD62, Q15015	Gene names	CTR9, KIAA0155, SH2BP1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1).

NACAM_MOUSE
NC score	0.019653 (rank : 285)	θ value	0.813845 (rank : 95)
Query Neighborhood Hits	185	Target Neighborhood Hits	1866	Shared Neighborhood Hits	32
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

DEK_MOUSE
NC score	0.019141 (rank : 286)	θ value	5.27518 (rank : 157)
Query Neighborhood Hits	185	Target Neighborhood Hits	280	Shared Neighborhood Hits	16
SwissProt Accessions	Q7TNV0, Q80VC5, Q8BZV6	Gene names	Dek
Domain Architecture	No domain graphic available
Description	Protein DEK.

CTR9_MOUSE
NC score	0.017589 (rank : 287)	θ value	8.99809 (rank : 173)
Query Neighborhood Hits	185	Target Neighborhood Hits	427	Shared Neighborhood Hits	26
SwissProt Accessions	Q62018, Q3UFF5, Q3UY40, Q66JX4, Q7TPS6, Q8BND9, Q8BRD1, Q8C9W7, Q8C9Y3, Q8CHI1	Gene names	Ctr9, Kiaa0155, Sh2bp1
Domain Architecture	No domain graphic available
Description	RNA polymerase-associated protein CTR9 homolog (SH2 domain-binding protein 1) (Tetratricopeptide repeat-containing, SH2-binding phosphoprotein of 150 kDa) (TPR-containing, SH2-binding phosphoprotein of 150 kDa) (p150TSP).

M3K10_HUMAN
NC score	0.016846 (rank : 288)	θ value	0.813845 (rank : 94)
Query Neighborhood Hits	185	Target Neighborhood Hits	1071	Shared Neighborhood Hits	52
SwissProt Accessions	Q02779, Q12761, Q14871	Gene names	MAP3K10, MLK2, MST
Domain Architecture
Description	Mitogen-activated protein kinase kinase kinase 10 (EC 2.7.11.25) (Mixed lineage kinase 2) (Protein kinase MST).

FA47B_HUMAN
NC score	0.016629 (rank : 289)	θ value	1.38821 (rank : 104)
Query Neighborhood Hits	185	Target Neighborhood Hits	431	Shared Neighborhood Hits	8
SwissProt Accessions	Q8NA70, Q5JQN5, Q6PIG3	Gene names	FAM47B
Domain Architecture	No domain graphic available
Description	Protein FAM47B.

TCOF_MOUSE
NC score	0.016003 (rank : 290)	θ value	8.99809 (rank : 185)
Query Neighborhood Hits	185	Target Neighborhood Hits	471	Shared Neighborhood Hits	12
SwissProt Accessions	O08784, O08857	Gene names	Tcof1
Domain Architecture
Description	Treacle protein (Treacher Collins syndrome protein homolog).

LCE2A_HUMAN
NC score	0.015809 (rank : 291)	θ value	8.99809 (rank : 177)
Query Neighborhood Hits	185	Target Neighborhood Hits	50	Shared Neighborhood Hits	1
SwissProt Accessions	Q5TA79	Gene names	LCE2A, LEP9
Domain Architecture	No domain graphic available
Description	Late cornified envelope protein 2A (Late envelope protein 9).

GOPC_MOUSE
NC score	0.015728 (rank : 292)	θ value	2.36792 (rank : 116)
Query Neighborhood Hits	185	Target Neighborhood Hits	323	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BH60, Q8BSV4, Q920R1, Q9ET11	Gene names	Gopc
Domain Architecture	No domain graphic available
Description	Golgi-associated PDZ and coiled-coil motif-containing protein (PDZ protein interacting specifically with TC10) (PIST).

LAMB3_HUMAN
NC score	0.013792 (rank : 293)	θ value	2.36792 (rank : 122)
Query Neighborhood Hits	185	Target Neighborhood Hits	461	Shared Neighborhood Hits	44
SwissProt Accessions	Q13751, O14947, Q14733, Q9UJK4, Q9UJL1	Gene names	LAMB3
Domain Architecture
Description	Laminin beta-3 chain precursor (Laminin 5 beta 3) (Laminin B1k chain) (Kalinin B1 chain).

SC11A_HUMAN
NC score	0.011736 (rank : 294)	θ value	0.62314 (rank : 88)
Query Neighborhood Hits	185	Target Neighborhood Hits	111	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UI33, Q68K15, Q8NDX3, Q9UHE0, Q9UHM0	Gene names	SCN11A, PN5, SCN12A, SNS2
Domain Architecture	No domain graphic available
Description	Sodium channel protein type 11 subunit alpha (Sodium channel protein type XI subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.9) (Sensory neuron sodium channel 2) (Peripheral nerve sodium channel 5) (hNaN).

HRX_HUMAN
NC score	0.011580 (rank : 295)	θ value	6.88961 (rank : 166)
Query Neighborhood Hits	185	Target Neighborhood Hits	825	Shared Neighborhood Hits	17
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

ASXL1_HUMAN
NC score	0.009803 (rank : 296)	θ value	6.88961 (rank : 164)
Query Neighborhood Hits	185	Target Neighborhood Hits	260	Shared Neighborhood Hits	10
SwissProt Accessions	Q8IXJ9, Q5JWS9, Q8IYY7, Q9H466, Q9NQF8, Q9UFJ0, Q9UFP8, Q9Y2I4	Gene names	ASXL1, KIAA0978
Domain Architecture	No domain graphic available
Description	Putative Polycomb group protein ASXL1 (Additional sex combs-like protein 1).

ZC3H6_MOUSE
NC score	0.009740 (rank : 297)	θ value	4.03905 (rank : 154)
Query Neighborhood Hits	185	Target Neighborhood Hits	239	Shared Neighborhood Hits	8
SwissProt Accessions	Q8BYK8, Q80UK3, Q8C1H1, Q9D604	Gene names	Zc3h6, Zc3hdc6
Domain Architecture
Description	Zinc finger CCCH domain-containing protein 6.

OXSM_HUMAN
NC score	0.007883 (rank : 298)	θ value	8.99809 (rank : 183)
Query Neighborhood Hits	185	Target Neighborhood Hits	13	Shared Neighborhood Hits	2
SwissProt Accessions	Q9NWU1	Gene names	OXSM
Domain Architecture	No domain graphic available
Description	3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial precursor (EC 2.3.1.41) (Beta-ketoacyl synthase).

NCOA2_HUMAN
NC score	0.007535 (rank : 299)	θ value	3.0926 (rank : 131)
Query Neighborhood Hits	185	Target Neighborhood Hits	281	Shared Neighborhood Hits	7
SwissProt Accessions	Q15596	Gene names	NCOA2, TIF2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2).

CO4A2_HUMAN
NC score	0.005841 (rank : 300)	θ value	0.21417 (rank : 72)
Query Neighborhood Hits	185	Target Neighborhood Hits	454	Shared Neighborhood Hits	6
SwissProt Accessions	P08572	Gene names	COL4A2
Domain Architecture
Description	Collagen alpha-2(IV) chain precursor.

LPIN2_HUMAN
NC score	0.005340 (rank : 301)	θ value	6.88961 (rank : 167)
Query Neighborhood Hits	185	Target Neighborhood Hits	117	Shared Neighborhood Hits	3
SwissProt Accessions	Q92539	Gene names	LPIN2, KIAA0249
Domain Architecture	No domain graphic available
Description	Lipin-2.

ZFP13_MOUSE
NC score	-0.007098 (rank : 302)	θ value	6.88961 (rank : 171)
Query Neighborhood Hits	185	Target Neighborhood Hits	771	Shared Neighborhood Hits	3
SwissProt Accessions	P10754, Q80WS0, Q8CDD0	Gene names	Zfp13, Krox-8, Zfp-13
Domain Architecture	No domain graphic available
Description	Zinc finger protein 13 (Zfp-13) (Krox-8 protein).