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Network neighborhood for query Sequence : DGKA_HUMAN

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DGKA_HUMAN
SwissProt Accessions	P23743, O75481, O75482, O75483	Gene names	DGKA, DAGK, DAGK1
Domain Architecture
Description	Diacylglycerol kinase alpha (EC 2.7.1.107) (Diglyceride kinase alpha) (DGK-alpha) (DAG kinase alpha) (80 kDa diacylglycerol kinase).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

DGKA_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	151	Target Neighborhood Hits	151	Shared Neighborhood Hits	151
SwissProt Accessions	P23743, O75481, O75482, O75483	Gene names	DGKA, DAGK, DAGK1
Domain Architecture
Description	Diacylglycerol kinase alpha (EC 2.7.1.107) (Diglyceride kinase alpha) (DGK-alpha) (DAG kinase alpha) (80 kDa diacylglycerol kinase).

DGKA_MOUSE
θ value	0 (rank : 2)	NC score	0.982097 (rank : 2)
Query Neighborhood Hits	151	Target Neighborhood Hits	146	Shared Neighborhood Hits	114
SwissProt Accessions	O88673, Q922X2	Gene names	Dgka, Dagk1
Domain Architecture
Description	Diacylglycerol kinase alpha (EC 2.7.1.107) (Diglyceride kinase alpha) (DGK-alpha) (DAG kinase alpha) (80 kDa diacylglycerol kinase).

DGKB_HUMAN
θ value	0 (rank : 3)	NC score	0.959154 (rank : 5)
Query Neighborhood Hits	151	Target Neighborhood Hits	238	Shared Neighborhood Hits	123
SwissProt Accessions	Q9Y6T7, O75241, Q75MF9, Q75MU7, Q86UI5, Q86UM9, Q9UQ29	Gene names	DGKB, DAGK2, KIAA0718
Domain Architecture
Description	Diacylglycerol kinase beta (EC 2.7.1.107) (Diglyceride kinase beta) (DGK-beta) (DAG kinase beta) (90 kDa diacylglycerol kinase).

DGKG_HUMAN
θ value	0 (rank : 4)	NC score	0.970963 (rank : 3)
Query Neighborhood Hits	151	Target Neighborhood Hits	171	Shared Neighborhood Hits	108
SwissProt Accessions	P49619	Gene names	DGKG, DAGK3
Domain Architecture
Description	Diacylglycerol kinase gamma (EC 2.7.1.107) (Diglyceride kinase gamma) (DGK-gamma) (DAG kinase gamma).

DGKG_MOUSE
θ value	0 (rank : 5)	NC score	0.970343 (rank : 4)
Query Neighborhood Hits	151	Target Neighborhood Hits	188	Shared Neighborhood Hits	110
SwissProt Accessions	Q91WG7	Gene names	Dgkg, Dagk3
Domain Architecture
Description	Diacylglycerol kinase gamma (EC 2.7.1.107) (Diglyceride kinase gamma) (DGK-gamma) (DAG kinase gamma) (88 kDa diacylglycerol kinase).

DGKE_HUMAN
θ value	4.67263e-73 (rank : 6)	NC score	0.893616 (rank : 6)
Query Neighborhood Hits	151	Target Neighborhood Hits	32	Shared Neighborhood Hits	25
SwissProt Accessions	P52429, Q9UKQ3	Gene names	DGKE, DAGK5
Domain Architecture
Description	Diacylglycerol kinase epsilon (EC 2.7.1.107) (Diglyceride kinase epsilon) (DGK-epsilon) (DAG kinase epsilon).

DGKE_MOUSE
θ value	6.10265e-73 (rank : 7)	NC score	0.892328 (rank : 7)
Query Neighborhood Hits	151	Target Neighborhood Hits	30	Shared Neighborhood Hits	24
SwissProt Accessions	Q9R1C6	Gene names	Dgke
Domain Architecture
Description	Diacylglycerol kinase epsilon (EC 2.7.1.107) (Diglyceride kinase epsilon) (DGK-epsilon) (DAG kinase epsilon).

DGKZ_MOUSE
θ value	3.95564e-72 (rank : 8)	NC score	0.739273 (rank : 11)
Query Neighborhood Hits	151	Target Neighborhood Hits	542	Shared Neighborhood Hits	18
SwissProt Accessions	Q80UP3	Gene names	Dgkz
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

DGKI_HUMAN
θ value	5.1662e-72 (rank : 9)	NC score	0.727088 (rank : 14)
Query Neighborhood Hits	151	Target Neighborhood Hits	609	Shared Neighborhood Hits	18
SwissProt Accessions	O75912, Q9NZ49	Gene names	DGKI
Domain Architecture
Description	Diacylglycerol kinase iota (EC 2.7.1.107) (Diglyceride kinase iota) (DGK-iota) (DAG kinase iota).

DGKZ_HUMAN
θ value	2.56397e-71 (rank : 10)	NC score	0.734863 (rank : 13)
Query Neighborhood Hits	151	Target Neighborhood Hits	551	Shared Neighborhood Hits	17
SwissProt Accessions	Q13574, O00542	Gene names	DGKZ, DAGK6
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

DGKQ_HUMAN
θ value	1.08223e-53 (rank : 11)	NC score	0.879516 (rank : 8)
Query Neighborhood Hits	151	Target Neighborhood Hits	131	Shared Neighborhood Hits	67
SwissProt Accessions	P52824	Gene names	DGKQ, DAGK4
Domain Architecture
Description	Diacylglycerol kinase theta (EC 2.7.1.107) (Diglyceride kinase theta) (DGK-theta) (DAG kinase theta).

DGKD_HUMAN
θ value	7.01481e-53 (rank : 12)	NC score	0.796114 (rank : 9)
Query Neighborhood Hits	151	Target Neighborhood Hits	231	Shared Neighborhood Hits	62
SwissProt Accessions	Q16760, Q14158, Q6PK55, Q8NG53	Gene names	DGKD, KIAA0145
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase delta (EC 2.7.1.107) (Diglyceride kinase delta) (DGK-delta) (DAG kinase delta) (130 kDa diacylglycerol kinase).

DGKH_HUMAN
θ value	1.19655e-52 (rank : 13)	NC score	0.790582 (rank : 10)
Query Neighborhood Hits	151	Target Neighborhood Hits	255	Shared Neighborhood Hits	62
SwissProt Accessions	Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9	Gene names	DGKH
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).

DGKK_HUMAN
θ value	1.36902e-48 (rank : 14)	NC score	0.739081 (rank : 12)
Query Neighborhood Hits	151	Target Neighborhood Hits	378	Shared Neighborhood Hits	41
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

MRCKG_MOUSE
θ value	2.36244e-08 (rank : 15)	NC score	0.106631 (rank : 106)
Query Neighborhood Hits	151	Target Neighborhood Hits	1466	Shared Neighborhood Hits	51
SwissProt Accessions	Q80UW5	Gene names	Cdc42bpg
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42- binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma).

MRCKG_HUMAN
θ value	4.0297e-08 (rank : 16)	NC score	0.104232 (rank : 110)
Query Neighborhood Hits	151	Target Neighborhood Hits	1519	Shared Neighborhood Hits	57
SwissProt Accessions	Q6DT37, O00565	Gene names	CDC42BPG
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42- binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma).

KPCG_HUMAN
θ value	1.29631e-06 (rank : 17)	NC score	0.127043 (rank : 77)
Query Neighborhood Hits	151	Target Neighborhood Hits	1126	Shared Neighborhood Hits	62
SwissProt Accessions	P05129	Gene names	PRKCG, PKCG
Domain Architecture
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

KPCG_MOUSE
θ value	2.21117e-06 (rank : 18)	NC score	0.126677 (rank : 78)
Query Neighborhood Hits	151	Target Neighborhood Hits	1123	Shared Neighborhood Hits	62
SwissProt Accessions	P63318, P05697	Gene names	Prkcg, Pkcc, Pkcg, Prkcc
Domain Architecture	No domain graphic available
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

KPCD_HUMAN
θ value	2.44474e-05 (rank : 19)	NC score	0.127281 (rank : 76)
Query Neighborhood Hits	151	Target Neighborhood Hits	900	Shared Neighborhood Hits	63
SwissProt Accessions	Q05655, Q15144	Gene names	PRKCD
Domain Architecture
Description	Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta).

KPCL_HUMAN
θ value	3.19293e-05 (rank : 20)	NC score	0.128693 (rank : 72)
Query Neighborhood Hits	151	Target Neighborhood Hits	887	Shared Neighborhood Hits	62
SwissProt Accessions	P24723, Q16246	Gene names	PRKCH, PKCL
Domain Architecture
Description	Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta) (PKC-L).

KPCB_HUMAN
θ value	4.1701e-05 (rank : 21)	NC score	0.121153 (rank : 90)
Query Neighborhood Hits	151	Target Neighborhood Hits	1121	Shared Neighborhood Hits	57
SwissProt Accessions	P05771, O43744, P05127, Q15138, Q93060, Q9UE49, Q9UE50, Q9UEH8, Q9UJ30, Q9UJ33	Gene names	PRKCB1, PKCB, PRKCB
Domain Architecture
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

KPCB_MOUSE
θ value	4.1701e-05 (rank : 22)	NC score	0.121214 (rank : 89)
Query Neighborhood Hits	151	Target Neighborhood Hits	1117	Shared Neighborhood Hits	57
SwissProt Accessions	P68404, P04410, P04411	Gene names	Prkcb1, Pkcb, Prkcb
Domain Architecture	No domain graphic available
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

KPCT_HUMAN
θ value	4.1701e-05 (rank : 23)	NC score	0.122553 (rank : 86)
Query Neighborhood Hits	151	Target Neighborhood Hits	897	Shared Neighborhood Hits	62
SwissProt Accessions	Q04759, Q3MJF1, Q64FY5, Q9H508, Q9H549	Gene names	PRKCQ, PRKCT
Domain Architecture
Description	Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta).

KPCT_MOUSE
θ value	4.1701e-05 (rank : 24)	NC score	0.122819 (rank : 85)
Query Neighborhood Hits	151	Target Neighborhood Hits	895	Shared Neighborhood Hits	62
SwissProt Accessions	Q02111	Gene names	Prkcq, Pkcq
Domain Architecture
Description	Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta).

KPCD_MOUSE
θ value	5.44631e-05 (rank : 25)	NC score	0.127643 (rank : 75)
Query Neighborhood Hits	151	Target Neighborhood Hits	888	Shared Neighborhood Hits	63
SwissProt Accessions	P28867, Q91V85, Q9Z333	Gene names	Prkcd, Pkcd
Domain Architecture
Description	Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta).

KPCA_HUMAN
θ value	9.29e-05 (rank : 26)	NC score	0.116374 (rank : 92)
Query Neighborhood Hits	151	Target Neighborhood Hits	1070	Shared Neighborhood Hits	59
SwissProt Accessions	P17252, Q15137, Q96RE4	Gene names	PRKCA, PKCA, PRKACA
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

KPCA_MOUSE
θ value	9.29e-05 (rank : 27)	NC score	0.116098 (rank : 93)
Query Neighborhood Hits	151	Target Neighborhood Hits	1067	Shared Neighborhood Hits	59
SwissProt Accessions	P20444	Gene names	Prkca, Pkca
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

CHP2_MOUSE
θ value	0.000461057 (rank : 28)	NC score	0.229400 (rank : 20)
Query Neighborhood Hits	151	Target Neighborhood Hits	122	Shared Neighborhood Hits	62
SwissProt Accessions	Q9D869	Gene names	Chp2, Hca520
Domain Architecture
Description	Calcineurin B homologous protein 2 (Hepatocellular carcinoma- associated antigen 520 homolog).

GUC1A_MOUSE
θ value	0.000461057 (rank : 29)	NC score	0.240298 (rank : 17)
Query Neighborhood Hits	151	Target Neighborhood Hits	152	Shared Neighborhood Hits	67
SwissProt Accessions	P43081	Gene names	Guca1a, Gcap, Gcap1, Guca1
Domain Architecture
Description	Guanylyl cyclase-activating protein 1 (GCAP 1) (Guanylate cyclase activator 1A).

KPCL_MOUSE
θ value	0.000461057 (rank : 30)	NC score	0.125492 (rank : 79)
Query Neighborhood Hits	151	Target Neighborhood Hits	891	Shared Neighborhood Hits	62
SwissProt Accessions	P23298	Gene names	Prkch, Pkch
Domain Architecture
Description	Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta) (PKC-L).

CANB2_MOUSE
θ value	0.000602161 (rank : 31)	NC score	0.234213 (rank : 19)
Query Neighborhood Hits	151	Target Neighborhood Hits	173	Shared Neighborhood Hits	68
SwissProt Accessions	Q63811	Gene names	Ppp3r2
Domain Architecture
Description	Calcineurin subunit B isoform 2 (Protein phosphatase 2B regulatory subunit 2) (Protein phosphatase 3 regulatory subunit B beta isoform).

CANB2_HUMAN
θ value	0.000786445 (rank : 32)	NC score	0.228586 (rank : 21)
Query Neighborhood Hits	151	Target Neighborhood Hits	163	Shared Neighborhood Hits	66
SwissProt Accessions	Q96LZ3, Q7Z4V8, Q8WYJ4	Gene names	PPP3R2, CBLP
Domain Architecture	No domain graphic available
Description	Calcineurin subunit B isoform 2 (Protein phosphatase 2B regulatory subunit 2) (Protein phosphatase 3 regulatory subunit B beta isoform) (Calcineurin B-like protein) (CBLP) (CNBII).

GUC1A_HUMAN
θ value	0.00102713 (rank : 33)	NC score	0.238712 (rank : 18)
Query Neighborhood Hits	151	Target Neighborhood Hits	147	Shared Neighborhood Hits	67
SwissProt Accessions	P43080, Q9NU14	Gene names	GUCA1A, GCAP, GCAP1, GUCA1
Domain Architecture
Description	Guanylyl cyclase-activating protein 1 (GCAP 1) (Guanylate cyclase activator 1A).

HPCL1_MOUSE
θ value	0.00102713 (rank : 34)	NC score	0.226997 (rank : 26)
Query Neighborhood Hits	151	Target Neighborhood Hits	149	Shared Neighborhood Hits	66
SwissProt Accessions	P62748, P35333	Gene names	Hpcal1
Domain Architecture	No domain graphic available
Description	Hippocalcin-like protein 1 (Visinin-like protein 3) (VILIP-3) (Neural visinin-like protein 3) (NVL-3) (NVP-3).

KIP1_MOUSE
θ value	0.00102713 (rank : 35)	NC score	0.273545 (rank : 15)
Query Neighborhood Hits	151	Target Neighborhood Hits	109	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Z0F4, Q3TN80	Gene names	Cib1, Cib, Kip, Prkdcip
Domain Architecture
Description	Calcium and integrin-binding protein 1 (Calmyrin) (DNA-PKcs- interacting protein) (Kinase-interacting protein) (KIP) (CIB).

KPCI_HUMAN
θ value	0.00102713 (rank : 36)	NC score	0.102724 (rank : 116)
Query Neighborhood Hits	151	Target Neighborhood Hits	885	Shared Neighborhood Hits	59
SwissProt Accessions	P41743, Q8WW06	Gene names	PRKCI, DXS1179E
Domain Architecture
Description	Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota) (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota) (PRKC-lambda/iota).

KPCI_MOUSE
θ value	0.00102713 (rank : 37)	NC score	0.102778 (rank : 115)
Query Neighborhood Hits	151	Target Neighborhood Hits	888	Shared Neighborhood Hits	61
SwissProt Accessions	Q62074	Gene names	Prkci, Pkcl
Domain Architecture
Description	Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota) (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota).

KPCZ_HUMAN
θ value	0.00102713 (rank : 38)	NC score	0.108742 (rank : 101)
Query Neighborhood Hits	151	Target Neighborhood Hits	884	Shared Neighborhood Hits	61
SwissProt Accessions	Q05513, Q15207, Q5SYT5, Q969S4	Gene names	PRKCZ, PKC2
Domain Architecture
Description	Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta).

KPCZ_MOUSE
θ value	0.00102713 (rank : 39)	NC score	0.110041 (rank : 99)
Query Neighborhood Hits	151	Target Neighborhood Hits	882	Shared Neighborhood Hits	61
SwissProt Accessions	Q02956	Gene names	Prkcz, Pkcz
Domain Architecture
Description	Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta).

CHP2_HUMAN
θ value	0.00134147 (rank : 40)	NC score	0.217128 (rank : 34)
Query Neighborhood Hits	151	Target Neighborhood Hits	122	Shared Neighborhood Hits	57
SwissProt Accessions	O43745	Gene names	CHP2, HCA520
Domain Architecture
Description	Calcineurin B homologous protein 2 (Hepatocellular carcinoma- associated antigen 520).

HPCL1_HUMAN
θ value	0.00134147 (rank : 41)	NC score	0.225375 (rank : 29)
Query Neighborhood Hits	151	Target Neighborhood Hits	150	Shared Neighborhood Hits	65
SwissProt Accessions	P37235, Q969S5	Gene names	HPCAL1, BDR1
Domain Architecture
Description	Hippocalcin-like protein 1 (Visinin-like protein 3) (VILIP-3) (Calcium-binding protein BDR-1) (HLP2).

HPCA_HUMAN
θ value	0.00175202 (rank : 42)	NC score	0.225691 (rank : 27)
Query Neighborhood Hits	151	Target Neighborhood Hits	156	Shared Neighborhood Hits	66
SwissProt Accessions	P84074, P32076, P41211, P70510	Gene names	HPCA, BDR2
Domain Architecture	No domain graphic available
Description	Neuron-specific calcium-binding protein hippocalcin (Calcium-binding protein BDR-2).

HPCA_MOUSE
θ value	0.00175202 (rank : 43)	NC score	0.225691 (rank : 28)
Query Neighborhood Hits	151	Target Neighborhood Hits	156	Shared Neighborhood Hits	66
SwissProt Accessions	P84075, P32076, P41211, P70510	Gene names	Hpca
Domain Architecture	No domain graphic available
Description	Neuron-specific calcium-binding protein hippocalcin.

MRCKB_MOUSE
θ value	0.00175202 (rank : 44)	NC score	0.090451 (rank : 129)
Query Neighborhood Hits	151	Target Neighborhood Hits	2180	Shared Neighborhood Hits	63
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

NCALD_HUMAN
θ value	0.00228821 (rank : 45)	NC score	0.227365 (rank : 24)
Query Neighborhood Hits	151	Target Neighborhood Hits	153	Shared Neighborhood Hits	67
SwissProt Accessions	P61601, P29554, Q8IYC3, Q9H0W2	Gene names	NCALD
Domain Architecture
Description	Neurocalcin delta.

NCALD_MOUSE
θ value	0.00228821 (rank : 46)	NC score	0.227365 (rank : 25)
Query Neighborhood Hits	151	Target Neighborhood Hits	153	Shared Neighborhood Hits	67
SwissProt Accessions	Q91X97, Q3TJS9, Q8BZN9	Gene names	Ncald, D15Ertd412e
Domain Architecture
Description	Neurocalcin delta.

RECO_HUMAN
θ value	0.00228821 (rank : 47)	NC score	0.188655 (rank : 52)
Query Neighborhood Hits	151	Target Neighborhood Hits	101	Shared Neighborhood Hits	60
SwissProt Accessions	P35243	Gene names	RCVRN, RCV1
Domain Architecture
Description	Recoverin (Cancer-associated retinopathy protein) (Protein CAR).

KPCE_HUMAN
θ value	0.00390308 (rank : 48)	NC score	0.124053 (rank : 84)
Query Neighborhood Hits	151	Target Neighborhood Hits	906	Shared Neighborhood Hits	59
SwissProt Accessions	Q02156, Q53SL4, Q53SM5, Q9UE81	Gene names	PRKCE, PKCE
Domain Architecture
Description	Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon).

KPCE_MOUSE
θ value	0.00390308 (rank : 49)	NC score	0.124398 (rank : 83)
Query Neighborhood Hits	151	Target Neighborhood Hits	906	Shared Neighborhood Hits	59
SwissProt Accessions	P16054	Gene names	Prkce, Pkce, Pkcea
Domain Architecture
Description	Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon).

RECO_MOUSE
θ value	0.00390308 (rank : 50)	NC score	0.199655 (rank : 38)
Query Neighborhood Hits	151	Target Neighborhood Hits	108	Shared Neighborhood Hits	61
SwissProt Accessions	P34057	Gene names	Rcvrn, Rcv1
Domain Architecture
Description	Recoverin (Cancer-associated retinopathy protein) (Protein CAR) (23 kDa photoreceptor cell-specific protein).

KIP1_HUMAN
θ value	0.00509761 (rank : 51)	NC score	0.261789 (rank : 16)
Query Neighborhood Hits	151	Target Neighborhood Hits	105	Shared Neighborhood Hits	56
SwissProt Accessions	Q99828, O00693, O00735, Q6IB49, Q96J54, Q99971	Gene names	CIB1, CIB, KIP, PRKDCIP
Domain Architecture
Description	Calcium and integrin-binding protein 1 (Calmyrin) (DNA-PKcs- interacting protein) (Kinase-interacting protein) (KIP) (CIB) (SNK- interacting protein 2-28) (SIP2-28).

KPCD3_MOUSE
θ value	0.00509761 (rank : 52)	NC score	0.091740 (rank : 128)
Query Neighborhood Hits	151	Target Neighborhood Hits	901	Shared Neighborhood Hits	61
SwissProt Accessions	Q8K1Y2	Gene names	Prkd3, Prkcn
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) (nPKC-nu).

CANB1_HUMAN
θ value	0.00665767 (rank : 53)	NC score	0.227556 (rank : 22)
Query Neighborhood Hits	151	Target Neighborhood Hits	183	Shared Neighborhood Hits	66
SwissProt Accessions	P63098, P06705, P15117, Q08044	Gene names	PPP3R1, CNA2, CNB
Domain Architecture	No domain graphic available
Description	Calcineurin subunit B isoform 1 (Protein phosphatase 2B regulatory subunit 1) (Protein phosphatase 3 regulatory subunit B alpha isoform 1).

CANB1_MOUSE
θ value	0.00665767 (rank : 54)	NC score	0.227513 (rank : 23)
Query Neighborhood Hits	151	Target Neighborhood Hits	183	Shared Neighborhood Hits	66
SwissProt Accessions	Q63810	Gene names	Ppp3r1, Cnb
Domain Architecture
Description	Calcineurin subunit B isoform 1 (Protein phosphatase 2B regulatory subunit 1) (Protein phosphatase 3 regulatory subunit B alpha isoform 1).

CHP1_MOUSE
θ value	0.00869519 (rank : 55)	NC score	0.211683 (rank : 35)
Query Neighborhood Hits	151	Target Neighborhood Hits	117	Shared Neighborhood Hits	59
SwissProt Accessions	P61022, Q62877, Q6ZWQ8	Gene names	Chp, Sid470
Domain Architecture
Description	Calcium-binding protein p22 (Calcium-binding protein CHP) (Calcineurin homologous protein) (Sid 470).

GUC1B_MOUSE
θ value	0.00869519 (rank : 56)	NC score	0.224334 (rank : 30)
Query Neighborhood Hits	151	Target Neighborhood Hits	116	Shared Neighborhood Hits	63
SwissProt Accessions	Q8VBV8	Gene names	Guca1b
Domain Architecture	No domain graphic available
Description	Guanylyl cyclase-activating protein 2 (GCAP 2) (Guanylate cyclase activator 1B).

KCIP2_HUMAN
θ value	0.00869519 (rank : 57)	NC score	0.196926 (rank : 41)
Query Neighborhood Hits	151	Target Neighborhood Hits	125	Shared Neighborhood Hits	63
SwissProt Accessions	Q9NS61, Q7Z6F1, Q96K86, Q96T41, Q96T42, Q96T43, Q96T44, Q9H0N4, Q9HD10, Q9HD11, Q9NS60, Q9NY10, Q9NZI1	Gene names	KCNIP2, KCHIP2
Domain Architecture	No domain graphic available
Description	Kv channel-interacting protein 2 (KChIP2) (A-type potassium channel modulatory protein 2) (Potassium channel-interacting protein 2) (Cardiac voltage-gated potassium channel modulatory subunit).

CHP1_HUMAN
θ value	0.0113563 (rank : 58)	NC score	0.209437 (rank : 36)
Query Neighborhood Hits	151	Target Neighborhood Hits	114	Shared Neighborhood Hits	59
SwissProt Accessions	Q99653	Gene names	CHP
Domain Architecture
Description	Calcium-binding protein p22 (Calcium-binding protein CHP) (Calcineurin homologous protein) (Calcineurin B homolog).

KPCD3_HUMAN
θ value	0.0148317 (rank : 59)	NC score	0.092219 (rank : 127)
Query Neighborhood Hits	151	Target Neighborhood Hits	895	Shared Neighborhood Hits	61
SwissProt Accessions	O94806	Gene names	PRKD3, EPK2, PRKCN
Domain Architecture
Description	Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) (nPKC-nu) (Protein kinase EPK2).

MRCKA_HUMAN
θ value	0.0148317 (rank : 60)	NC score	0.093563 (rank : 125)
Query Neighborhood Hits	151	Target Neighborhood Hits	1999	Shared Neighborhood Hits	61
SwissProt Accessions	Q5VT25, Q59GZ1, Q5H9N9, Q5T797, Q5VT26, Q5VT27, Q86XX2, Q86XX3, Q99646	Gene names	CDC42BPA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42- binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) (DMPK-like alpha).

KCIP2_MOUSE
θ value	0.0193708 (rank : 61)	NC score	0.194519 (rank : 45)
Query Neighborhood Hits	151	Target Neighborhood Hits	124	Shared Neighborhood Hits	63
SwissProt Accessions	Q9JJ69, Q6DTJ2, Q8K1T8, Q8K1T9, Q8K1U0, Q8VHN4, Q8VHN5, Q8VHN6, Q9JJ68	Gene names	Kcnip2, Kchip2
Domain Architecture	No domain graphic available
Description	Kv channel-interacting protein 2 (KChIP2) (A-type potassium channel modulatory protein 2) (Potassium channel-interacting protein 2).

KPCD2_HUMAN
θ value	0.0252991 (rank : 62)	NC score	0.087373 (rank : 132)
Query Neighborhood Hits	151	Target Neighborhood Hits	910	Shared Neighborhood Hits	62
SwissProt Accessions	Q9BZL6, Q8TB08, Q9P0T6, Q9Y3X8	Gene names	PRKD2, PKD2
Domain Architecture
Description	Serine/threonine-protein kinase D2 (EC 2.7.11.13) (nPKC-D2).

MRCKB_HUMAN
θ value	0.0252991 (rank : 63)	NC score	0.088241 (rank : 130)
Query Neighborhood Hits	151	Target Neighborhood Hits	2239	Shared Neighborhood Hits	63
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

STAC3_HUMAN
θ value	0.0252991 (rank : 64)	NC score	0.183893 (rank : 55)
Query Neighborhood Hits	151	Target Neighborhood Hits	228	Shared Neighborhood Hits	52
SwissProt Accessions	Q96MF2, Q96HU5	Gene names	STAC3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

STAC3_MOUSE
θ value	0.0252991 (rank : 65)	NC score	0.183843 (rank : 56)
Query Neighborhood Hits	151	Target Neighborhood Hits	232	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BZ71	Gene names	Stac3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

TCF8_MOUSE
θ value	0.0252991 (rank : 66)	NC score	0.006818 (rank : 294)
Query Neighborhood Hits	151	Target Neighborhood Hits	1067	Shared Neighborhood Hits	7
SwissProt Accessions	Q64318, Q62519	Gene names	Tcf8, Zfhx1a, Zfx1a, Zfx1ha
Domain Architecture
Description	Transcription factor 8 (Zinc finger homeobox protein 1a) (MEB1) (Delta EF1).

GUC1B_HUMAN
θ value	0.0330416 (rank : 67)	NC score	0.221713 (rank : 31)
Query Neighborhood Hits	151	Target Neighborhood Hits	124	Shared Neighborhood Hits	63
SwissProt Accessions	Q9UMX6, Q9NU15	Gene names	GUCA1B, GCAP2
Domain Architecture
Description	Guanylyl cyclase-activating protein 2 (GCAP 2) (Guanylate cyclase activator 1B).

KPCD1_MOUSE
θ value	0.0330416 (rank : 68)	NC score	0.087871 (rank : 131)
Query Neighborhood Hits	151	Target Neighborhood Hits	891	Shared Neighborhood Hits	61
SwissProt Accessions	Q62101	Gene names	Prkd1, Pkcm, Pkd, Prkcm
Domain Architecture
Description	Serine/threonine-protein kinase D1 (EC 2.7.11.13) (nPKC-D1) (Protein kinase D) (Protein kinase C mu type) (nPKC-mu).

CHIN_HUMAN
θ value	0.0431538 (rank : 69)	NC score	0.150658 (rank : 66)
Query Neighborhood Hits	151	Target Neighborhood Hits	227	Shared Neighborhood Hits	59
SwissProt Accessions	P15882, Q53SD6, Q53SH5, Q96FB0	Gene names	CHN1, ARHGAP2, CHN
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

KPCD1_HUMAN
θ value	0.0431538 (rank : 70)	NC score	0.087154 (rank : 133)
Query Neighborhood Hits	151	Target Neighborhood Hits	901	Shared Neighborhood Hits	61
SwissProt Accessions	Q15139	Gene names	PRKD1, PKD, PKD1, PRKCM
Domain Architecture
Description	Serine/threonine-protein kinase D1 (EC 2.7.11.13) (nPKC-D1) (Protein kinase D) (Protein kinase C mu type) (nPKC-mu).

STAC_MOUSE
θ value	0.0431538 (rank : 71)	NC score	0.198547 (rank : 39)
Query Neighborhood Hits	151	Target Neighborhood Hits	268	Shared Neighborhood Hits	54
SwissProt Accessions	P97306	Gene names	Stac
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

CALL3_HUMAN
θ value	0.0736092 (rank : 72)	NC score	0.125064 (rank : 80)
Query Neighborhood Hits	151	Target Neighborhood Hits	225	Shared Neighborhood Hits	64
SwissProt Accessions	P27482	Gene names	CALML3
Domain Architecture
Description	Calmodulin-like protein 3 (Calmodulin-related protein NB-1) (CaM-like protein) (CLP).

KCIP4_HUMAN
θ value	0.0736092 (rank : 73)	NC score	0.192559 (rank : 47)
Query Neighborhood Hits	151	Target Neighborhood Hits	136	Shared Neighborhood Hits	64
SwissProt Accessions	Q6PIL6, Q4W5G8, Q8NEU0, Q9BWT2, Q9H294, Q9H2A4	Gene names	KCNIP4, CALP, KCHIP4
Domain Architecture	No domain graphic available
Description	Kv channel-interacting protein 4 (KChIP4) (A-type potassium channel modulatory protein 4) (Potassium channel-interacting protein 4) (Calsenilin-like protein).

KCIP4_MOUSE
θ value	0.0736092 (rank : 74)	NC score	0.192689 (rank : 46)
Query Neighborhood Hits	151	Target Neighborhood Hits	136	Shared Neighborhood Hits	64
SwissProt Accessions	Q6PHZ8, Q6DTJ3, Q8CAD0, Q8R4I2, Q9EQ01	Gene names	Kcnip4, Calp, Kchip4
Domain Architecture	No domain graphic available
Description	Kv channel-interacting protein 4 (KChIP4) (A-type potassium channel modulatory protein 4) (Potassium channel-interacting protein 4) (Calsenilin-like protein).

LAMA2_MOUSE
θ value	0.0736092 (rank : 75)	NC score	0.019131 (rank : 283)
Query Neighborhood Hits	151	Target Neighborhood Hits	1198	Shared Neighborhood Hits	16
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

CETN2_HUMAN
θ value	0.0961366 (rank : 76)	NC score	0.110342 (rank : 98)
Query Neighborhood Hits	151	Target Neighborhood Hits	213	Shared Neighborhood Hits	63
SwissProt Accessions	P41208, Q53XW1	Gene names	CETN2, CALT, CEN2
Domain Architecture
Description	Centrin-2 (Caltractin isoform 1).

GUC1C_HUMAN
θ value	0.0961366 (rank : 77)	NC score	0.217748 (rank : 33)
Query Neighborhood Hits	151	Target Neighborhood Hits	148	Shared Neighborhood Hits	67
SwissProt Accessions	O95843, O95844, Q9UNM0	Gene names	GUCA1C, GCAP3
Domain Architecture
Description	Guanylyl cyclase-activating protein 3 (GCAP 3) (Guanylate cyclase activator 1C).

AYTL1_HUMAN
θ value	0.125558 (rank : 78)	NC score	0.113898 (rank : 95)
Query Neighborhood Hits	151	Target Neighborhood Hits	140	Shared Neighborhood Hits	62
SwissProt Accessions	Q7L5N7, Q6MZJ6, Q9NX23	Gene names	AYTL1
Domain Architecture	No domain graphic available
Description	Acyltransferase-like 1 (EC 2.3.1.-).

LAMA2_HUMAN
θ value	0.125558 (rank : 79)	NC score	0.016618 (rank : 287)
Query Neighborhood Hits	151	Target Neighborhood Hits	1092	Shared Neighborhood Hits	14
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

RGNEF_MOUSE
θ value	0.125558 (rank : 80)	NC score	0.061317 (rank : 200)
Query Neighborhood Hits	151	Target Neighborhood Hits	641	Shared Neighborhood Hits	53
SwissProt Accessions	P97433	Gene names	Rgnef, Rhoip2
Domain Architecture
Description	Rho-guanine nucleotide exchange factor (Rho-interacting protein 2) (RhoGEF) (RIP2).

UBP32_HUMAN
θ value	0.125558 (rank : 81)	NC score	0.101075 (rank : 119)
Query Neighborhood Hits	151	Target Neighborhood Hits	170	Shared Neighborhood Hits	48
SwissProt Accessions	Q8NFA0, Q9BX85, Q9Y591	Gene names	USP32, USP10
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 32 (EC 3.1.2.15) (Ubiquitin thioesterase 32) (Ubiquitin-specific-processing protease 32) (Deubiquitinating enzyme 32) (NY-REN-60 antigen).

CALM_HUMAN
θ value	0.163984 (rank : 82)	NC score	0.124684 (rank : 81)
Query Neighborhood Hits	151	Target Neighborhood Hits	232	Shared Neighborhood Hits	65
SwissProt Accessions	P62158, P02593, P70667, P99014, Q13942, Q53S29, Q61379, Q61380, Q96HK3	Gene names	CALM1, CALM, CAM, CAM1
Domain Architecture
Description	Calmodulin (CaM).

CALM_MOUSE
θ value	0.163984 (rank : 83)	NC score	0.124684 (rank : 82)
Query Neighborhood Hits	151	Target Neighborhood Hits	232	Shared Neighborhood Hits	65
SwissProt Accessions	P62204, P02593, P70667, P99014, Q61379, Q61380	Gene names	Calm1, Calm, Cam, Cam1
Domain Architecture
Description	Calmodulin (CaM).

CETN3_HUMAN
θ value	0.163984 (rank : 84)	NC score	0.104183 (rank : 111)
Query Neighborhood Hits	151	Target Neighborhood Hits	211	Shared Neighborhood Hits	62
SwissProt Accessions	O15182, Q9BS23	Gene names	CETN3, CEN3
Domain Architecture
Description	Centrin-3.

CETN3_MOUSE
θ value	0.163984 (rank : 85)	NC score	0.104428 (rank : 109)
Query Neighborhood Hits	151	Target Neighborhood Hits	208	Shared Neighborhood Hits	62
SwissProt Accessions	O35648	Gene names	Cetn3, Cen3
Domain Architecture
Description	Centrin-3.

STAC_HUMAN
θ value	0.163984 (rank : 86)	NC score	0.190099 (rank : 49)
Query Neighborhood Hits	151	Target Neighborhood Hits	276	Shared Neighborhood Hits	55
SwissProt Accessions	Q99469	Gene names	STAC
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

CETN2_MOUSE
θ value	0.21417 (rank : 87)	NC score	0.107608 (rank : 103)
Query Neighborhood Hits	151	Target Neighborhood Hits	211	Shared Neighborhood Hits	63
SwissProt Accessions	Q9R1K9, Q3UBB4, Q9CWM0	Gene names	Cetn2, Calt
Domain Architecture
Description	Centrin-2 (Caltractin isoform 1).

RASF1_MOUSE
θ value	0.21417 (rank : 88)	NC score	0.207705 (rank : 37)
Query Neighborhood Hits	151	Target Neighborhood Hits	74	Shared Neighborhood Hits	55
SwissProt Accessions	Q99MK9, Q9WUF5	Gene names	Rassf1
Domain Architecture	No domain graphic available
Description	Ras association domain-containing protein 1 (Protein 123F2).

CABP7_HUMAN
θ value	0.279714 (rank : 89)	NC score	0.128497 (rank : 73)
Query Neighborhood Hits	151	Target Neighborhood Hits	205	Shared Neighborhood Hits	61
SwissProt Accessions	Q86V35	Gene names	CABP7
Domain Architecture
Description	Calcium-binding protein 7 (CaBP7).

CABP7_MOUSE
θ value	0.279714 (rank : 90)	NC score	0.128497 (rank : 74)
Query Neighborhood Hits	151	Target Neighborhood Hits	205	Shared Neighborhood Hits	61
SwissProt Accessions	Q91ZM8	Gene names	Cabp7
Domain Architecture
Description	Calcium-binding protein 7 (CaBP7).

CALB2_HUMAN
θ value	0.279714 (rank : 91)	NC score	0.112932 (rank : 96)
Query Neighborhood Hits	151	Target Neighborhood Hits	149	Shared Neighborhood Hits	52
SwissProt Accessions	P22676, Q53HD2, Q96BK4	Gene names	CALB2, CAB29
Domain Architecture
Description	Calretinin (CR) (29 kDa calbindin).

CALB2_MOUSE
θ value	0.279714 (rank : 92)	NC score	0.114038 (rank : 94)
Query Neighborhood Hits	151	Target Neighborhood Hits	141	Shared Neighborhood Hits	52
SwissProt Accessions	Q08331, Q60964, Q9JM81	Gene names	Calb2
Domain Architecture
Description	Calretinin (CR).

MYO9B_HUMAN
θ value	0.279714 (rank : 93)	NC score	0.051727 (rank : 268)
Query Neighborhood Hits	151	Target Neighborhood Hits	641	Shared Neighborhood Hits	51
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

EFHD1_HUMAN
θ value	0.365318 (rank : 94)	NC score	0.121280 (rank : 88)
Query Neighborhood Hits	151	Target Neighborhood Hits	108	Shared Neighborhood Hits	42
SwissProt Accessions	Q9BUP0, Q9BTF8, Q9H8I2, Q9HBQ0	Gene names	EFHD1, SWS2
Domain Architecture
Description	EF-hand domain-containing protein 1 (Swiprosin-2).

FSTL5_MOUSE
θ value	0.365318 (rank : 95)	NC score	0.036210 (rank : 277)
Query Neighborhood Hits	151	Target Neighborhood Hits	355	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BFR2, Q80TG3, Q8C4T3	Gene names	Fstl5, Kiaa1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5) (m- D/Bsp120I 1-2).

MLL3_HUMAN
θ value	0.365318 (rank : 96)	NC score	0.020375 (rank : 282)
Query Neighborhood Hits	151	Target Neighborhood Hits	1644	Shared Neighborhood Hits	14
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

MYO9B_MOUSE
θ value	0.365318 (rank : 97)	NC score	0.050913 (rank : 271)
Query Neighborhood Hits	151	Target Neighborhood Hits	311	Shared Neighborhood Hits	51
SwissProt Accessions	Q9QY06, Q9QY07, Q9QY08, Q9QY09	Gene names	Myo9b, Myr5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

TCF8_HUMAN
θ value	0.365318 (rank : 98)	NC score	0.003717 (rank : 297)
Query Neighborhood Hits	151	Target Neighborhood Hits	1057	Shared Neighborhood Hits	6
SwissProt Accessions	P37275, Q12924, Q13800	Gene names	TCF8, AREB6
Domain Architecture
Description	Transcription factor 8 (NIL-2-A zinc finger protein) (Negative regulator of IL2).

AYT1A_MOUSE
θ value	0.47712 (rank : 99)	NC score	0.103393 (rank : 113)
Query Neighborhood Hits	151	Target Neighborhood Hits	126	Shared Neighborhood Hits	59
SwissProt Accessions	Q8BYI6	Gene names	Aytl1a, Aytl1
Domain Architecture	No domain graphic available
Description	Acyltransferase-like 1-A (EC 2.3.1.-).

ITB6_MOUSE
θ value	0.47712 (rank : 100)	NC score	0.014923 (rank : 290)
Query Neighborhood Hits	151	Target Neighborhood Hits	341	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z0T9	Gene names	Itgb6
Domain Architecture
Description	Integrin beta-6 precursor.

SPHK2_MOUSE
θ value	0.47712 (rank : 101)	NC score	0.054499 (rank : 257)
Query Neighborhood Hits	151	Target Neighborhood Hits	78	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JIA7, Q91VA9, Q9DBH6	Gene names	Sphk2
Domain Architecture
Description	Sphingosine kinase 2 (EC 2.7.1.-) (SK 2) (SPK 2).

CETN1_HUMAN
θ value	0.62314 (rank : 102)	NC score	0.105828 (rank : 108)
Query Neighborhood Hits	151	Target Neighborhood Hits	232	Shared Neighborhood Hits	63
SwissProt Accessions	Q12798	Gene names	CETN1, CEN1, CETN
Domain Architecture
Description	Centrin-1 (Caltractin isoform 2).

DUOX1_HUMAN
θ value	0.62314 (rank : 103)	NC score	0.120723 (rank : 91)
Query Neighborhood Hits	151	Target Neighborhood Hits	172	Shared Neighborhood Hits	64
SwissProt Accessions	Q9NRD9, Q6ZMB3, Q6ZR09, Q9NZC1	Gene names	DUOX1, DUOX, LNOX1, THOX1
Domain Architecture	No domain graphic available
Description	Dual oxidase 1 precursor (EC 1.6.3.1) (EC 1.11.1.-) (NADPH thyroid oxidase 1) (Thyroid oxidase 1) (Large NOX 1) (Long NOX 1).

DUOX2_HUMAN
θ value	0.62314 (rank : 104)	NC score	0.121868 (rank : 87)
Query Neighborhood Hits	151	Target Neighborhood Hits	139	Shared Neighborhood Hits	62
SwissProt Accessions	Q9NRD8, Q9NR02, Q9UHF9	Gene names	DUOX2, LNOX2, THOX2
Domain Architecture	No domain graphic available
Description	Dual oxidase 2 precursor (EC 1.6.3.1) (EC 1.11.1.-) (NADPH oxidase/peroxidase DUOX2) (NADPH thyroid oxidase 2) (Thyroid oxidase 2) (NADH/NADPH thyroid oxidase p138-tox) (p138 thyroid oxidase) (Large NOX 2) (Long NOX 2).

KCIP1_HUMAN
θ value	0.62314 (rank : 105)	NC score	0.196069 (rank : 44)
Query Neighborhood Hits	151	Target Neighborhood Hits	113	Shared Neighborhood Hits	60
SwissProt Accessions	Q9NZI2, Q5U822	Gene names	KCNIP1, KCHIP1, VABP
Domain Architecture	No domain graphic available
Description	Kv channel-interacting protein 1 (KChIP1) (A-type potassium channel modulatory protein 1) (Potassium channel-interacting protein 1) (Vesicle APC-binding protein).

KCIP1_MOUSE
θ value	0.62314 (rank : 106)	NC score	0.196953 (rank : 40)
Query Neighborhood Hits	151	Target Neighborhood Hits	113	Shared Neighborhood Hits	60
SwissProt Accessions	Q9JJ57, Q5SSA3, Q6DTJ1, Q8BGJ4, Q8C4K4, Q8CGL1, Q8K1U1, Q8K3M2	Gene names	Kcnip1, Kchip1
Domain Architecture	No domain graphic available
Description	Kv channel-interacting protein 1 (KChIP1) (A-type potassium channel modulatory protein 1) (Potassium channel-interacting protein 1).

CHIN_MOUSE
θ value	0.813845 (rank : 107)	NC score	0.145724 (rank : 68)
Query Neighborhood Hits	151	Target Neighborhood Hits	229	Shared Neighborhood Hits	59
SwissProt Accessions	Q91V57, Q3UGY3, Q7TQE5, Q8BWU6, Q9D9B3	Gene names	Chn1, Arhgap2
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

FKBP7_HUMAN
θ value	0.813845 (rank : 108)	NC score	0.028539 (rank : 279)
Query Neighborhood Hits	151	Target Neighborhood Hits	46	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y680, Q86U65, Q96DA4, Q9Y6B0	Gene names	FKBP7, FKBP23
Domain Architecture
Description	FK506-binding protein 7 precursor (EC 5.2.1.8) (Peptidyl-prolyl cis- trans isomerase) (PPIase) (Rotamase) (FKBP-23).

PRD15_HUMAN
θ value	0.813845 (rank : 109)	NC score	0.000454 (rank : 298)
Query Neighborhood Hits	151	Target Neighborhood Hits	805	Shared Neighborhood Hits	10
SwissProt Accessions	P57071, Q8N0X3, Q8NEX0, Q9NQV3	Gene names	PRDM15, C21orf83, ZNF298
Domain Architecture
Description	PR domain zinc finger protein 15 (PR domain-containing protein 15) (Zinc finger protein 298).

FKBP7_MOUSE
θ value	1.06291 (rank : 110)	NC score	0.022945 (rank : 281)
Query Neighborhood Hits	151	Target Neighborhood Hits	58	Shared Neighborhood Hits	11
SwissProt Accessions	O54998	Gene names	Fkbp7, Fkbp23
Domain Architecture
Description	FK506-binding protein 7 precursor (EC 5.2.1.8) (Peptidyl-prolyl cis- trans isomerase) (PPIase) (Rotamase) (FKBP-23).

KIP2_HUMAN
θ value	1.06291 (rank : 111)	NC score	0.150873 (rank : 65)
Query Neighborhood Hits	151	Target Neighborhood Hits	107	Shared Neighborhood Hits	57
SwissProt Accessions	O75838	Gene names	CIB2, KIP2
Domain Architecture	No domain graphic available
Description	Calcium and integrin-binding protein 2 (Kinase-interacting protein 2) (KIP 2).

UN13B_HUMAN
θ value	1.06291 (rank : 112)	NC score	0.162859 (rank : 60)
Query Neighborhood Hits	151	Target Neighborhood Hits	217	Shared Neighborhood Hits	57
SwissProt Accessions	O14795	Gene names	UNC13B, UNC13
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

CALL5_HUMAN
θ value	1.38821 (rank : 113)	NC score	0.106831 (rank : 105)
Query Neighborhood Hits	151	Target Neighborhood Hits	231	Shared Neighborhood Hits	64
SwissProt Accessions	Q9NZT1, Q8IXU8	Gene names	CALML5, CLSP
Domain Architecture
Description	Calmodulin-like protein 5 (Calmodulin-like skin protein).

LAMB2_HUMAN
θ value	1.38821 (rank : 114)	NC score	0.017563 (rank : 285)
Query Neighborhood Hits	151	Target Neighborhood Hits	692	Shared Neighborhood Hits	13
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

LAMB2_MOUSE
θ value	1.38821 (rank : 115)	NC score	0.018801 (rank : 284)
Query Neighborhood Hits	151	Target Neighborhood Hits	722	Shared Neighborhood Hits	15
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

MLL3_MOUSE
θ value	1.38821 (rank : 116)	NC score	0.023391 (rank : 280)
Query Neighborhood Hits	151	Target Neighborhood Hits	1399	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

UN13A_HUMAN
θ value	1.38821 (rank : 117)	NC score	0.161645 (rank : 61)
Query Neighborhood Hits	151	Target Neighborhood Hits	285	Shared Neighborhood Hits	56
SwissProt Accessions	Q9UPW8	Gene names	UNC13A, KIAA1032
Domain Architecture	No domain graphic available
Description	Unc-13 homolog A (Munc13-1).

ZN335_HUMAN
θ value	1.38821 (rank : 118)	NC score	-0.000961 (rank : 299)
Query Neighborhood Hits	151	Target Neighborhood Hits	973	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H4Z2, Q9H684	Gene names	ZNF335
Domain Architecture	No domain graphic available
Description	Zinc finger protein 335.

CABP4_HUMAN
θ value	1.81305 (rank : 119)	NC score	0.099465 (rank : 121)
Query Neighborhood Hits	151	Target Neighborhood Hits	250	Shared Neighborhood Hits	62
SwissProt Accessions	P57796, Q8N4Z2, Q8WWY5	Gene names	CABP4
Domain Architecture
Description	Calcium-binding protein 4 (CaBP4).

CETN1_MOUSE
θ value	1.81305 (rank : 120)	NC score	0.102633 (rank : 117)
Query Neighborhood Hits	151	Target Neighborhood Hits	231	Shared Neighborhood Hits	64
SwissProt Accessions	P41209, Q3V119, Q9D9G9, Q9DAL6	Gene names	Cetn1, Calt
Domain Architecture
Description	Centrin-1 (Caltractin).

CHIO_HUMAN
θ value	1.81305 (rank : 121)	NC score	0.151995 (rank : 64)
Query Neighborhood Hits	151	Target Neighborhood Hits	220	Shared Neighborhood Hits	60
SwissProt Accessions	P52757, Q75MM2	Gene names	CHN2, ARHGAP3, BCH
Domain Architecture
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

CHIO_MOUSE
θ value	1.81305 (rank : 122)	NC score	0.158819 (rank : 62)
Query Neighborhood Hits	151	Target Neighborhood Hits	130	Shared Neighborhood Hits	60
SwissProt Accessions	Q80XD1, Q9D9W2, Q9ER57	Gene names	Chn2, Arhgap3, Bch
Domain Architecture	No domain graphic available
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

EFHD1_MOUSE
θ value	1.81305 (rank : 123)	NC score	0.103464 (rank : 112)
Query Neighborhood Hits	151	Target Neighborhood Hits	108	Shared Neighborhood Hits	44
SwissProt Accessions	Q9D4J1, Q543U4	Gene names	Efhd1, Sws2
Domain Architecture
Description	EF-hand domain-containing protein 1 (Swiprosin-2).

GRP3_HUMAN
θ value	1.81305 (rank : 124)	NC score	0.219925 (rank : 32)
Query Neighborhood Hits	151	Target Neighborhood Hits	131	Shared Neighborhood Hits	68
SwissProt Accessions	Q8IV61, O94931	Gene names	RASGRP3, GRP3, KIAA0846
Domain Architecture
Description	RAS guanyl-releasing protein 3 (Calcium and DAG-regulated guanine nucleotide exchange factor III) (Guanine nucleotide exchange factor for Rap1).

LAMB1_HUMAN
θ value	1.81305 (rank : 125)	NC score	0.016167 (rank : 288)
Query Neighborhood Hits	151	Target Neighborhood Hits	1018	Shared Neighborhood Hits	14
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

BRAP_HUMAN
θ value	2.36792 (rank : 126)	NC score	0.015740 (rank : 289)
Query Neighborhood Hits	151	Target Neighborhood Hits	560	Shared Neighborhood Hits	8
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

BRAP_MOUSE
θ value	2.36792 (rank : 127)	NC score	0.017184 (rank : 286)
Query Neighborhood Hits	151	Target Neighborhood Hits	409	Shared Neighborhood Hits	8
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

KIP2_MOUSE
θ value	2.36792 (rank : 128)	NC score	0.141950 (rank : 69)
Query Neighborhood Hits	151	Target Neighborhood Hits	110	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Z309	Gene names	Cib2, Kip2
Domain Architecture	No domain graphic available
Description	Calcium and integrin-binding protein 2 (Kinase-interacting protein 2) (KIP 2).

PCAT1_HUMAN
θ value	3.0926 (rank : 129)	NC score	0.082120 (rank : 137)
Query Neighborhood Hits	151	Target Neighborhood Hits	80	Shared Neighborhood Hits	50
SwissProt Accessions	Q8NF37, Q1HAQ1, Q7Z4G6, Q8N3U7, Q8WUL8, Q9GZW6	Gene names	AYTL2, LPCAT1, PFAAP3
Domain Architecture	No domain graphic available
Description	1-acylglycerophosphocholine O-acyltransferase 1 (EC 2.3.1.23) (Lung- type acyl-coa:lysophosphatidylcholine acyltransferase 1) (Acyltransferase-like 2) (Phosphonoformate immuno-associated protein 3).

RAF1_HUMAN
θ value	3.0926 (rank : 130)	NC score	0.053861 (rank : 263)
Query Neighborhood Hits	151	Target Neighborhood Hits	886	Shared Neighborhood Hits	58
SwissProt Accessions	P04049	Gene names	RAF1, RAF
Domain Architecture
Description	RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf- 1) (C-RAF) (cRaf).

RAF1_MOUSE
θ value	3.0926 (rank : 131)	NC score	0.054444 (rank : 258)
Query Neighborhood Hits	151	Target Neighborhood Hits	886	Shared Neighborhood Hits	58
SwissProt Accessions	Q99N57, Q91WH1	Gene names	Raf1, Craf
Domain Architecture
Description	RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf- 1) (C-RAF) (cRaf).

SPHK2_HUMAN
θ value	3.0926 (rank : 132)	NC score	0.056232 (rank : 242)
Query Neighborhood Hits	151	Target Neighborhood Hits	81	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NRA0, Q9BRN1, Q9H0Q2, Q9NWU7	Gene names	SPHK2
Domain Architecture
Description	Sphingosine kinase 2 (EC 2.7.1.-) (SK 2) (SPK 2).

KSR1_MOUSE
θ value	4.03905 (rank : 133)	NC score	0.039715 (rank : 276)
Query Neighborhood Hits	151	Target Neighborhood Hits	870	Shared Neighborhood Hits	46
SwissProt Accessions	Q61097, Q61648, Q78DX8	Gene names	Ksr1, Ksr
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-1 (Kinase suppressor of ras) (mKSR1) (Hb protein).

RGAP1_HUMAN
θ value	4.03905 (rank : 134)	NC score	0.042730 (rank : 275)
Query Neighborhood Hits	151	Target Neighborhood Hits	189	Shared Neighborhood Hits	38
SwissProt Accessions	Q9H0H5, Q6PJ26, Q9NWN2, Q9P250, Q9P2W2	Gene names	RACGAP1, KIAA1478, MGCRACGAP
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

RGAP1_MOUSE
θ value	4.03905 (rank : 135)	NC score	0.044632 (rank : 274)
Query Neighborhood Hits	151	Target Neighborhood Hits	185	Shared Neighborhood Hits	38
SwissProt Accessions	Q9WVM1, Q3THR5, Q3TI41, Q3TM81	Gene names	Racgap1, Mgcracgap
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

RASF5_HUMAN
θ value	5.27518 (rank : 136)	NC score	0.061220 (rank : 201)
Query Neighborhood Hits	151	Target Neighborhood Hits	79	Shared Neighborhood Hits	41
SwissProt Accessions	Q8WWW0, Q5SY32, Q8WWV9, Q8WXF4, Q9BT99	Gene names	RASSF5, NORE1, RAPL
Domain Architecture	No domain graphic available
Description	Ras association domain-containing family protein 5 (New ras effector 1) (Regulator for cell adhesion and polarization enriched in lymphoid tissues) (RAPL).

UBP4_MOUSE
θ value	5.27518 (rank : 137)	NC score	0.007315 (rank : 292)
Query Neighborhood Hits	151	Target Neighborhood Hits	90	Shared Neighborhood Hits	3
SwissProt Accessions	P35123, O54704	Gene names	Usp4, Unp
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.1.2.15) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Deubiquitinating enzyme 4) (Ubiquitous nuclear protein).

HRX_HUMAN
θ value	6.88961 (rank : 138)	NC score	0.013214 (rank : 291)
Query Neighborhood Hits	151	Target Neighborhood Hits	825	Shared Neighborhood Hits	13
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

NCS1_HUMAN
θ value	6.88961 (rank : 139)	NC score	0.188971 (rank : 50)
Query Neighborhood Hits	151	Target Neighborhood Hits	132	Shared Neighborhood Hits	64
SwissProt Accessions	P62166, P36610, Q9UK26	Gene names	FREQ, FLUP, NCS1
Domain Architecture
Description	Neuronal calcium sensor 1 (NCS-1) (Frequenin homolog) (Frequenin-like protein) (Frequenin-like ubiquitous protein).

NCS1_MOUSE
θ value	6.88961 (rank : 140)	NC score	0.188971 (rank : 51)
Query Neighborhood Hits	151	Target Neighborhood Hits	132	Shared Neighborhood Hits	64
SwissProt Accessions	Q8BNY6	Gene names	Freq, Ncs1
Domain Architecture
Description	Neuronal calcium sensor 1 (NCS-1) (Frequenin homolog).

RASF5_MOUSE
θ value	6.88961 (rank : 141)	NC score	0.067085 (rank : 160)
Query Neighborhood Hits	151	Target Neighborhood Hits	72	Shared Neighborhood Hits	45
SwissProt Accessions	Q5EBH1, O70407, Q6KAR0, Q8C2E8	Gene names	Rassf5, Nore1, Rapl
Domain Architecture	No domain graphic available
Description	Ras association domain-containing family protein 5 (New ras effector 1) (Regulator for cell adhesion and polarization enriched in lymphoid tissues) (RAPL).

SEGN_HUMAN
θ value	6.88961 (rank : 142)	NC score	0.077882 (rank : 140)
Query Neighborhood Hits	151	Target Neighborhood Hits	96	Shared Neighborhood Hits	42
SwissProt Accessions	O76038, Q5VV44, Q96QV7, Q9UJF6	Gene names	SCGN, SECRET
Domain Architecture
Description	Secretagogin.

TRI42_MOUSE
θ value	6.88961 (rank : 143)	NC score	0.007170 (rank : 293)
Query Neighborhood Hits	151	Target Neighborhood Hits	316	Shared Neighborhood Hits	7
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

UN13B_MOUSE
θ value	6.88961 (rank : 144)	NC score	0.152758 (rank : 63)
Query Neighborhood Hits	151	Target Neighborhood Hits	210	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Z1N9	Gene names	Unc13b, Unc13a
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

AYT1B_MOUSE
θ value	8.99809 (rank : 145)	NC score	0.098177 (rank : 122)
Query Neighborhood Hits	151	Target Neighborhood Hits	113	Shared Neighborhood Hits	58
SwissProt Accessions	Q9D5U0	Gene names	Aytl1b
Domain Architecture	No domain graphic available
Description	Acyltransferase-like 1-B (EC 2.3.1.-).

BSN_MOUSE
θ value	8.99809 (rank : 146)	NC score	0.006498 (rank : 295)
Query Neighborhood Hits	151	Target Neighborhood Hits	2057	Shared Neighborhood Hits	17
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

CALB1_HUMAN
θ value	8.99809 (rank : 147)	NC score	0.094699 (rank : 123)
Query Neighborhood Hits	151	Target Neighborhood Hits	130	Shared Neighborhood Hits	52
SwissProt Accessions	P05937	Gene names	CALB1, CAB27
Domain Architecture
Description	Calbindin (Vitamin D-dependent calcium-binding protein, avian-type) (Calbindin D28) (D-28K).

CALB1_MOUSE
θ value	8.99809 (rank : 148)	NC score	0.094029 (rank : 124)
Query Neighborhood Hits	151	Target Neighborhood Hits	129	Shared Neighborhood Hits	52
SwissProt Accessions	P12658, Q545N6	Gene names	Calb1
Domain Architecture
Description	Calbindin (Vitamin D-dependent calcium-binding protein, avian-type) (Calbindin D28) (D-28K) (Spot 35 protein) (PCD-29).

KSR1_HUMAN
θ value	8.99809 (rank : 149)	NC score	0.034409 (rank : 278)
Query Neighborhood Hits	151	Target Neighborhood Hits	867	Shared Neighborhood Hits	45
SwissProt Accessions	Q8IVT5, Q13476	Gene names	KSR1, KSR
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-1 (Kinase suppressor of ras).

NOX5_HUMAN
θ value	8.99809 (rank : 150)	NC score	0.107848 (rank : 102)
Query Neighborhood Hits	151	Target Neighborhood Hits	89	Shared Neighborhood Hits	51
SwissProt Accessions	Q96PH1, Q8TEQ1, Q8TER4, Q96PH2, Q96PJ8, Q96PJ9, Q9H6E0, Q9HAM8	Gene names	NOX5
Domain Architecture	No domain graphic available
Description	NADPH oxidase 5 (EC 1.6.3.-).

TRI42_HUMAN
θ value	8.99809 (rank : 151)	NC score	0.005441 (rank : 296)
Query Neighborhood Hits	151	Target Neighborhood Hits	283	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IWZ5, Q8N832, Q8NDL3	Gene names	TRIM42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

AKT1_HUMAN
θ value	θ > 10 (rank : 152)	NC score	0.065700 (rank : 165)
Query Neighborhood Hits	151	Target Neighborhood Hits	885	Shared Neighborhood Hits	33
SwissProt Accessions	P31749, Q9BWB6	Gene names	AKT1, PKB, RAC
Domain Architecture
Description	RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-alpha) (Protein kinase B) (PKB) (C-AKT).

AKT1_MOUSE
θ value	θ > 10 (rank : 153)	NC score	0.065445 (rank : 168)
Query Neighborhood Hits	151	Target Neighborhood Hits	878	Shared Neighborhood Hits	33
SwissProt Accessions	P31750, Q62274	Gene names	Akt1, Akt, Rac
Domain Architecture
Description	RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-alpha) (AKT1 kinase) (Protein kinase B) (PKB) (C-AKT) (Thymoma viral proto- oncogene).

AKT2_HUMAN
θ value	θ > 10 (rank : 154)	NC score	0.063896 (rank : 185)
Query Neighborhood Hits	151	Target Neighborhood Hits	878	Shared Neighborhood Hits	33
SwissProt Accessions	P31751, Q68GC0	Gene names	AKT2
Domain Architecture
Description	RAC-beta serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta).

AKT2_MOUSE
θ value	θ > 10 (rank : 155)	NC score	0.063992 (rank : 184)
Query Neighborhood Hits	151	Target Neighborhood Hits	875	Shared Neighborhood Hits	33
SwissProt Accessions	Q60823	Gene names	Akt2
Domain Architecture
Description	RAC-beta serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta).

AKT3_HUMAN
θ value	θ > 10 (rank : 156)	NC score	0.063417 (rank : 187)
Query Neighborhood Hits	151	Target Neighborhood Hits	872	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y243, Q96QV3, Q9UFP5	Gene names	AKT3
Domain Architecture
Description	RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-gamma) (Protein kinase Akt-3) (Protein kinase B, gamma) (PKB gamma) (STK-2).

AKT3_MOUSE
θ value	θ > 10 (rank : 157)	NC score	0.063430 (rank : 186)
Query Neighborhood Hits	151	Target Neighborhood Hits	872	Shared Neighborhood Hits	32
SwissProt Accessions	Q9WUA6	Gene names	Akt3
Domain Architecture
Description	RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-gamma) (Protein kinase Akt-3) (Protein kinase B, gamma) (PKB gamma).

ARBK1_HUMAN
θ value	θ > 10 (rank : 158)	NC score	0.062067 (rank : 192)
Query Neighborhood Hits	151	Target Neighborhood Hits	859	Shared Neighborhood Hits	32
SwissProt Accessions	P25098, Q13837	Gene names	ADRBK1, BARK, BARK1, GRK2
Domain Architecture
Description	Beta-adrenergic receptor kinase 1 (EC 2.7.11.15) (Beta-ARK-1) (G- protein coupled receptor kinase 2).

ARBK1_MOUSE
θ value	θ > 10 (rank : 159)	NC score	0.062066 (rank : 193)
Query Neighborhood Hits	151	Target Neighborhood Hits	849	Shared Neighborhood Hits	32
SwissProt Accessions	Q99MK8, Q99LL8	Gene names	Adrbk1, Grk2
Domain Architecture
Description	Beta-adrenergic receptor kinase 1 (EC 2.7.11.15) (Beta-ARK-1) (G- protein-coupled receptor kinase 2).

ARBK2_HUMAN
θ value	θ > 10 (rank : 160)	NC score	0.061851 (rank : 197)
Query Neighborhood Hits	151	Target Neighborhood Hits	849	Shared Neighborhood Hits	32
SwissProt Accessions	P35626, Q9UGW9	Gene names	ADRBK2, BARK2, GRK3
Domain Architecture
Description	Beta-adrenergic receptor kinase 2 (EC 2.7.11.15) (Beta-ARK-2) (G- protein-coupled receptor kinase 3).

CABP1_HUMAN
θ value	θ > 10 (rank : 161)	NC score	0.075391 (rank : 144)
Query Neighborhood Hits	151	Target Neighborhood Hits	197	Shared Neighborhood Hits	53
SwissProt Accessions	Q9NZU7, O95663, Q9NZU8	Gene names	CABP1
Domain Architecture
Description	Calcium-binding protein 1 (CaBP1) (Calbrain).

CABP1_MOUSE
θ value	θ > 10 (rank : 162)	NC score	0.075405 (rank : 143)
Query Neighborhood Hits	151	Target Neighborhood Hits	197	Shared Neighborhood Hits	53
SwissProt Accessions	Q9JLK7, Q9JLK6	Gene names	Cabp1
Domain Architecture
Description	Calcium-binding protein 1 (CaBP1).

CABP2_HUMAN
θ value	θ > 10 (rank : 163)	NC score	0.077899 (rank : 139)
Query Neighborhood Hits	151	Target Neighborhood Hits	205	Shared Neighborhood Hits	56
SwissProt Accessions	Q9NPB3	Gene names	CABP2
Domain Architecture
Description	Calcium-binding protein 2 (CaBP2).

CABP2_MOUSE
θ value	θ > 10 (rank : 164)	NC score	0.079810 (rank : 138)
Query Neighborhood Hits	151	Target Neighborhood Hits	204	Shared Neighborhood Hits	56
SwissProt Accessions	Q9JLK4, Q9JLK5	Gene names	Cabp2
Domain Architecture
Description	Calcium-binding protein 2 (CaBP2).

CABP3_HUMAN
θ value	θ > 10 (rank : 165)	NC score	0.085664 (rank : 134)
Query Neighborhood Hits	151	Target Neighborhood Hits	162	Shared Neighborhood Hits	52
SwissProt Accessions	Q9NZU6, Q9NYY0, Q9NZT9	Gene names	CABP3
Domain Architecture
Description	Calcium-binding protein 3 (CaBP3).

CABP4_MOUSE
θ value	θ > 10 (rank : 166)	NC score	0.092299 (rank : 126)
Query Neighborhood Hits	151	Target Neighborhood Hits	212	Shared Neighborhood Hits	61
SwissProt Accessions	Q8VHC5	Gene names	Cabp4
Domain Architecture	No domain graphic available
Description	Calcium-binding protein 4 (CaBP4).

CABP5_HUMAN
θ value	θ > 10 (rank : 167)	NC score	0.075730 (rank : 142)
Query Neighborhood Hits	151	Target Neighborhood Hits	197	Shared Neighborhood Hits	54
SwissProt Accessions	Q9NP86	Gene names	CABP5
Domain Architecture
Description	Calcium-binding protein 5 (CaBP5).

CABP5_MOUSE
θ value	θ > 10 (rank : 168)	NC score	0.076245 (rank : 141)
Query Neighborhood Hits	151	Target Neighborhood Hits	207	Shared Neighborhood Hits	58
SwissProt Accessions	Q9JLK3	Gene names	Cabp5
Domain Architecture
Description	Calcium-binding protein 5 (CaBP5).

CALL6_HUMAN
θ value	θ > 10 (rank : 169)	NC score	0.074105 (rank : 145)
Query Neighborhood Hits	151	Target Neighborhood Hits	157	Shared Neighborhood Hits	44
SwissProt Accessions	Q8TD86, Q6Q2C4	Gene names	CALML6, CAGLP, CALGP
Domain Architecture	No domain graphic available
Description	Calmodulin-like protein 6 (Calglandulin-like protein).

CALM4_MOUSE
θ value	θ > 10 (rank : 170)	NC score	0.103005 (rank : 114)
Query Neighborhood Hits	151	Target Neighborhood Hits	229	Shared Neighborhood Hits	59
SwissProt Accessions	Q9JM83, Q9CR31, Q9D1E9	Gene names	Calm4, Dd112
Domain Architecture
Description	Calmodulin-4 (Calcium-binding protein Dd112).

CALN1_HUMAN
θ value	θ > 10 (rank : 171)	NC score	0.082647 (rank : 135)
Query Neighborhood Hits	151	Target Neighborhood Hits	161	Shared Neighborhood Hits	50
SwissProt Accessions	Q9BXU9	Gene names	CALN1, CABP8
Domain Architecture
Description	Calneuron-1 (Calcium-binding protein CaBP8).

CALN1_MOUSE
θ value	θ > 10 (rank : 172)	NC score	0.082640 (rank : 136)
Query Neighborhood Hits	151	Target Neighborhood Hits	161	Shared Neighborhood Hits	50
SwissProt Accessions	Q9JJG7	Gene names	Caln1
Domain Architecture
Description	Calneuron-1.

CAYP1_HUMAN
θ value	θ > 10 (rank : 173)	NC score	0.068517 (rank : 157)
Query Neighborhood Hits	151	Target Neighborhood Hits	94	Shared Neighborhood Hits	36
SwissProt Accessions	Q13938, Q3MJA7, Q8WUZ3	Gene names	CAPS
Domain Architecture
Description	Calcyphosin (Calcyphosine).

CSEN_HUMAN
θ value	θ > 10 (rank : 174)	NC score	0.178663 (rank : 57)
Query Neighborhood Hits	151	Target Neighborhood Hits	128	Shared Neighborhood Hits	63
SwissProt Accessions	Q9Y2W7, Q53TJ5, Q96T40, Q9UJ84, Q9UJ85	Gene names	KCNIP3, CSEN, DREAM, KCHIP3
Domain Architecture
Description	Calsenilin (DRE-antagonist modulator) (DREAM) (Kv channel-interacting protein 3) (KChIP3) (A-type potassium channel modulatory protein 3).

CSEN_MOUSE
θ value	θ > 10 (rank : 175)	NC score	0.174910 (rank : 58)
Query Neighborhood Hits	151	Target Neighborhood Hits	117	Shared Neighborhood Hits	60
SwissProt Accessions	Q9QXT8, Q924L0, Q99PH9, Q99PI0, Q99PI2, Q99PI3, Q9JHZ5	Gene names	Kcnip3, Csen, Dream, Kchip3
Domain Architecture
Description	Calsenilin (DRE-antagonist modulator) (DREAM) (Kv channel-interacting protein 3) (A-type potassium channel modulatory protein 3) (KChIP3).

CTRO_HUMAN
θ value	θ > 10 (rank : 176)	NC score	0.057477 (rank : 234)
Query Neighborhood Hits	151	Target Neighborhood Hits	2092	Shared Neighborhood Hits	53
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

CTRO_MOUSE
θ value	θ > 10 (rank : 177)	NC score	0.054337 (rank : 261)
Query Neighborhood Hits	151	Target Neighborhood Hits	2344	Shared Neighborhood Hits	52
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

DMPK_HUMAN
θ value	θ > 10 (rank : 178)	NC score	0.070170 (rank : 153)
Query Neighborhood Hits	151	Target Neighborhood Hits	944	Shared Neighborhood Hits	33
SwissProt Accessions	Q09013, Q16205	Gene names	DMPK, MDPK
Domain Architecture
Description	Myotonin-protein kinase (EC 2.7.11.1) (Myotonic dystrophy protein kinase) (MDPK) (DM-kinase) (DMK) (DMPK) (MT-PK).

DMPK_MOUSE
θ value	θ > 10 (rank : 179)	NC score	0.070374 (rank : 151)
Query Neighborhood Hits	151	Target Neighborhood Hits	908	Shared Neighborhood Hits	32
SwissProt Accessions	P54265	Gene names	Dmpk, Dm15, Mdpk
Domain Architecture
Description	Myotonin-protein kinase (EC 2.7.11.1) (Myotonic dystrophy protein kinase) (MDPK) (DM-kinase) (DMK) (DMPK) (MT-PK).

EFCB1_HUMAN
θ value	θ > 10 (rank : 180)	NC score	0.191739 (rank : 48)
Query Neighborhood Hits	151	Target Neighborhood Hits	121	Shared Neighborhood Hits	62
SwissProt Accessions	Q9HAE3	Gene names	EFCAB1
Domain Architecture	No domain graphic available
Description	EF-hand calcium-binding domain-containing protein 1.

EFCB1_MOUSE
θ value	θ > 10 (rank : 181)	NC score	0.172737 (rank : 59)
Query Neighborhood Hits	151	Target Neighborhood Hits	126	Shared Neighborhood Hits	63
SwissProt Accessions	Q9D3N2, Q8BSW3, Q8C982, Q8CAI0, Q9D527, Q9D5E7	Gene names	Efcab1
Domain Architecture	No domain graphic available
Description	EF-hand calcium-binding domain-containing protein 1.

EFHD2_HUMAN
θ value	θ > 10 (rank : 182)	NC score	0.063251 (rank : 188)
Query Neighborhood Hits	151	Target Neighborhood Hits	86	Shared Neighborhood Hits	30
SwissProt Accessions	Q96C19	Gene names	EFHD2, SWS1
Domain Architecture
Description	EF-hand domain-containing protein 2 (Swiprosin-1).

EFHD2_MOUSE
θ value	θ > 10 (rank : 183)	NC score	0.070812 (rank : 150)
Query Neighborhood Hits	151	Target Neighborhood Hits	88	Shared Neighborhood Hits	31
SwissProt Accessions	Q9D8Y0, Q9D0P4	Gene names	Efhd2, Sws1
Domain Architecture
Description	EF-hand domain-containing protein 2 (Swiprosin-1).

F5006_HUMAN
θ value	θ > 10 (rank : 184)	NC score	0.055270 (rank : 247)
Query Neighborhood Hits	151	Target Neighborhood Hits	794	Shared Neighborhood Hits	32
SwissProt Accessions	Q96LW2, Q49A48	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized serine/threonine-protein kinase FLJ25006 (EC 2.7.11.1).

F5006_MOUSE
θ value	θ > 10 (rank : 185)	NC score	0.055090 (rank : 250)
Query Neighborhood Hits	151	Target Neighborhood Hits	793	Shared Neighborhood Hits	32
SwissProt Accessions	Q5SYL1	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized serine/threonine-protein kinase FLJ25006 (EC 2.7.11.1).

GRK4_HUMAN
θ value	θ > 10 (rank : 186)	NC score	0.061853 (rank : 196)
Query Neighborhood Hits	151	Target Neighborhood Hits	822	Shared Neighborhood Hits	30
SwissProt Accessions	P32298, O00641, O00642, Q13293, Q13294, Q13295, Q14453, Q14725, Q15313, Q15314, Q15315, Q15316	Gene names	GRK4, GPRK2L, GPRK4
Domain Architecture
Description	G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK4) (ITI1).

GRK4_MOUSE
θ value	θ > 10 (rank : 187)	NC score	0.062024 (rank : 194)
Query Neighborhood Hits	151	Target Neighborhood Hits	808	Shared Neighborhood Hits	30
SwissProt Accessions	O70291	Gene names	Grk4, Gprk2l
Domain Architecture
Description	G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK4).

GRK5_HUMAN
θ value	θ > 10 (rank : 188)	NC score	0.060730 (rank : 205)
Query Neighborhood Hits	151	Target Neighborhood Hits	819	Shared Neighborhood Hits	32
SwissProt Accessions	P34947	Gene names	GRK5, GPRK5
Domain Architecture
Description	G protein-coupled receptor kinase 5 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK5).

GRK5_MOUSE
θ value	θ > 10 (rank : 189)	NC score	0.060635 (rank : 208)
Query Neighborhood Hits	151	Target Neighborhood Hits	823	Shared Neighborhood Hits	32
SwissProt Accessions	Q8VEB1, O70292, O70297	Gene names	Grk5, Gprk5
Domain Architecture
Description	G protein-coupled receptor kinase 5 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK5).

GRK6_HUMAN
θ value	θ > 10 (rank : 190)	NC score	0.059784 (rank : 214)
Query Neighborhood Hits	151	Target Neighborhood Hits	823	Shared Neighborhood Hits	34
SwissProt Accessions	P43250, O60541, Q13652	Gene names	GRK6, GPRK6
Domain Architecture
Description	G protein-coupled receptor kinase 6 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK6).

GRK6_MOUSE
θ value	θ > 10 (rank : 191)	NC score	0.060069 (rank : 210)
Query Neighborhood Hits	151	Target Neighborhood Hits	820	Shared Neighborhood Hits	32
SwissProt Accessions	O70293, O70294, O70295	Gene names	Grk6, Gprk6
Domain Architecture
Description	G protein-coupled receptor kinase 6 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK6).

GRK7_HUMAN
θ value	θ > 10 (rank : 192)	NC score	0.061773 (rank : 198)
Query Neighborhood Hits	151	Target Neighborhood Hits	820	Shared Neighborhood Hits	32
SwissProt Accessions	Q8WTQ7	Gene names	GRK7, GPRK7
Domain Architecture
Description	G protein-coupled receptor kinase 7 precursor (EC 2.7.11.16) (G protein-coupled receptor kinase GRK7).

HPCL4_HUMAN
θ value	θ > 10 (rank : 193)	NC score	0.196437 (rank : 43)
Query Neighborhood Hits	151	Target Neighborhood Hits	123	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UM19, Q5TG97, Q8N611	Gene names	HPCAL4
Domain Architecture	No domain graphic available
Description	Hippocalcin-like protein 4 (HLP4).

HPCL4_MOUSE
θ value	θ > 10 (rank : 194)	NC score	0.196622 (rank : 42)
Query Neighborhood Hits	151	Target Neighborhood Hits	123	Shared Neighborhood Hits	62
SwissProt Accessions	Q8BGZ1	Gene names	Hpcal4
Domain Architecture	No domain graphic available
Description	Hippocalcin-like protein 4 (Neural visinin-like protein 2) (NVP-2).

KAPCA_HUMAN
θ value	θ > 10 (rank : 195)	NC score	0.059551 (rank : 217)
Query Neighborhood Hits	151	Target Neighborhood Hits	838	Shared Neighborhood Hits	32
SwissProt Accessions	P17612, Q9H2Y0, Q9NRB4, Q9NRH9	Gene names	PRKACA, PKACA
Domain Architecture
Description	cAMP-dependent protein kinase, alpha-catalytic subunit (EC 2.7.11.11) (PKA C-alpha).

KAPCA_MOUSE
θ value	θ > 10 (rank : 196)	NC score	0.059728 (rank : 216)
Query Neighborhood Hits	151	Target Neighborhood Hits	836	Shared Neighborhood Hits	32
SwissProt Accessions	P05132, Q9JID0	Gene names	Prkaca, Pkaca
Domain Architecture
Description	cAMP-dependent protein kinase, alpha-catalytic subunit (EC 2.7.11.11) (PKA C-alpha).

KAPCB_HUMAN
θ value	θ > 10 (rank : 197)	NC score	0.059955 (rank : 212)
Query Neighborhood Hits	151	Target Neighborhood Hits	837	Shared Neighborhood Hits	32
SwissProt Accessions	P22694, Q59GC0, Q5BNE9, Q5BNF0, Q5BNF1, Q5BNF2, Q5BNF3, Q5CZ92, Q5T1K3, Q7Z3M1, Q8IYR5, Q8IZQ0	Gene names	PRKACB
Domain Architecture
Description	cAMP-dependent protein kinase, beta-catalytic subunit (EC 2.7.11.11) (PKA C-beta).

KAPCB_MOUSE
θ value	θ > 10 (rank : 198)	NC score	0.060028 (rank : 211)
Query Neighborhood Hits	151	Target Neighborhood Hits	836	Shared Neighborhood Hits	32
SwissProt Accessions	P68181, P05206, Q3TQH5, Q3UDD0, Q3UTH5	Gene names	Prkacb, Pkacb
Domain Architecture	No domain graphic available
Description	cAMP-dependent protein kinase, beta-catalytic subunit (EC 2.7.11.11) (PKA C-beta).

KAPCG_HUMAN
θ value	θ > 10 (rank : 199)	NC score	0.057939 (rank : 229)
Query Neighborhood Hits	151	Target Neighborhood Hits	845	Shared Neighborhood Hits	32
SwissProt Accessions	P22612, O60850, Q86YI1	Gene names	PRKACG
Domain Architecture
Description	cAMP-dependent protein kinase, gamma-catalytic subunit (EC 2.7.11.11) (PKA C-gamma).

KGP1A_HUMAN
θ value	θ > 10 (rank : 200)	NC score	0.058164 (rank : 225)
Query Neighborhood Hits	151	Target Neighborhood Hits	901	Shared Neighborhood Hits	32
SwissProt Accessions	Q13976	Gene names	PRKG1, PRKGR1A
Domain Architecture
Description	cGMP-dependent protein kinase 1, alpha isozyme (EC 2.7.11.12) (CGK 1 alpha) (cGKI-alpha).

KGP1B_HUMAN
θ value	θ > 10 (rank : 201)	NC score	0.058105 (rank : 228)
Query Neighborhood Hits	151	Target Neighborhood Hits	921	Shared Neighborhood Hits	32
SwissProt Accessions	P14619	Gene names	PRKG1, PRKG1B, PRKGR1B
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

KGP1B_MOUSE
θ value	θ > 10 (rank : 202)	NC score	0.058127 (rank : 226)
Query Neighborhood Hits	151	Target Neighborhood Hits	922	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Z0Z0	Gene names	Prkg1, Prkg1b, Prkgr1b
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

KGP2_HUMAN
θ value	θ > 10 (rank : 203)	NC score	0.055843 (rank : 245)
Query Neighborhood Hits	151	Target Neighborhood Hits	1023	Shared Neighborhood Hits	32
SwissProt Accessions	Q13237, O00125, O60916	Gene names	PRKG2, PRKGR2
Domain Architecture
Description	cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).

KGP2_MOUSE
θ value	θ > 10 (rank : 204)	NC score	0.056031 (rank : 244)
Query Neighborhood Hits	151	Target Neighborhood Hits	1029	Shared Neighborhood Hits	32
SwissProt Accessions	Q61410	Gene names	Prkg2, Prkgr2
Domain Architecture
Description	cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).

KIP3_HUMAN
θ value	θ > 10 (rank : 205)	NC score	0.136571 (rank : 70)
Query Neighborhood Hits	151	Target Neighborhood Hits	83	Shared Neighborhood Hits	50
SwissProt Accessions	Q96Q77	Gene names	CIB3, KIP3
Domain Architecture
Description	Calcium and integrin-binding protein 3 (Kinase-interacting protein 3) (KIP 3).

KS6A1_HUMAN
θ value	θ > 10 (rank : 206)	NC score	0.054821 (rank : 254)
Query Neighborhood Hits	151	Target Neighborhood Hits	854	Shared Neighborhood Hits	32
SwissProt Accessions	Q15418, Q5SVM5, Q5SVM8, Q5SVM9, Q96C05, Q9BQK2	Gene names	RPS6KA1, RSK1
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1) (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (p90S6K) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A).

KS6A1_MOUSE
θ value	θ > 10 (rank : 207)	NC score	0.055043 (rank : 251)
Query Neighborhood Hits	151	Target Neighborhood Hits	850	Shared Neighborhood Hits	32
SwissProt Accessions	P18653	Gene names	Rps6ka1, Rsk1
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1) (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (p90S6K) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A).

KS6A2_HUMAN
θ value	θ > 10 (rank : 208)	NC score	0.054622 (rank : 255)
Query Neighborhood Hits	151	Target Neighborhood Hits	857	Shared Neighborhood Hits	32
SwissProt Accessions	Q15349, Q15419, Q59GJ3, Q5TI68, Q96J38, Q9UJN5	Gene names	RPS6KA2, RSK3
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1) (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (MAP kinase-activated protein kinase 1c) (MAPKAPK1C).

KS6A2_MOUSE
θ value	θ > 10 (rank : 209)	NC score	0.054429 (rank : 260)
Query Neighborhood Hits	151	Target Neighborhood Hits	858	Shared Neighborhood Hits	32
SwissProt Accessions	Q9WUT3, Q9D2C0	Gene names	Rps6ka2, Rsk3
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1) (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (Protein-tyrosine kinase Mpk-9) (MAP kinase- activated protein kinase 1c) (MAPKAPK1C).

KS6A3_HUMAN
θ value	θ > 10 (rank : 210)	NC score	0.054840 (rank : 252)
Query Neighborhood Hits	151	Target Neighborhood Hits	859	Shared Neighborhood Hits	32
SwissProt Accessions	P51812, Q4VAP3, Q59H26, Q5JPK8, Q7Z3Z7	Gene names	RPS6KA3, ISPK1, RSK2
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1) (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protein kinase 1b) (MAPKAPK1B).

KS6A3_MOUSE
θ value	θ > 10 (rank : 211)	NC score	0.054839 (rank : 253)
Query Neighborhood Hits	151	Target Neighborhood Hits	860	Shared Neighborhood Hits	32
SwissProt Accessions	P18654, Q03140, Q8K3J8	Gene names	Rps6ka3, Rps6ka-rs1, Rsk2
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1) (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (MAP kinase-activated protein kinase 1b) (MAPKAPK1B).

KS6A4_HUMAN
θ value	θ > 10 (rank : 212)	NC score	0.060643 (rank : 207)
Query Neighborhood Hits	151	Target Neighborhood Hits	868	Shared Neighborhood Hits	32
SwissProt Accessions	O75676, O75585, Q53ES8	Gene names	RPS6KA4, MSK2
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-4 (EC 2.7.11.1) (Nuclear mitogen- and stress-activated protein kinase 2) (90 kDa ribosomal protein S6 kinase 4) (Ribosomal protein kinase B) (RSKB).

KS6A4_MOUSE
θ value	θ > 10 (rank : 213)	NC score	0.060481 (rank : 209)
Query Neighborhood Hits	151	Target Neighborhood Hits	866	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Z2B9, Q91X18	Gene names	Rps6ka4, Msk2
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-4 (EC 2.7.11.1) (Nuclear mitogen- and stress-activated protein kinase 2) (90 kDa ribosomal protein S6 kinase 4) (RSK-like protein kinase) (RLSK).

KS6A5_HUMAN
θ value	θ > 10 (rank : 214)	NC score	0.059272 (rank : 221)
Query Neighborhood Hits	151	Target Neighborhood Hits	855	Shared Neighborhood Hits	32
SwissProt Accessions	O75582, O95316, Q96AF7	Gene names	RPS6KA5, MSK1
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1) (Nuclear mitogen- and stress-activated protein kinase 1) (90 kDa ribosomal protein S6 kinase 5) (RSK-like protein kinase) (RSKL).

KS6A5_MOUSE
θ value	θ > 10 (rank : 215)	NC score	0.061865 (rank : 195)
Query Neighborhood Hits	151	Target Neighborhood Hits	854	Shared Neighborhood Hits	32
SwissProt Accessions	Q8C050, Q8CI92	Gene names	Rps6ka5, Msk1
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1) (Nuclear mitogen- and stress-activated protein kinase 1) (90 kDa ribosomal protein S6 kinase 5) (RSK-like protein kinase) (RLSK).

KS6A6_HUMAN
θ value	θ > 10 (rank : 216)	NC score	0.055325 (rank : 246)
Query Neighborhood Hits	151	Target Neighborhood Hits	853	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UK32, Q8WX28, Q9H4S6	Gene names	RPS6KA6, RSK4
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-6 (EC 2.7.11.1) (S6K-alpha 6) (90 kDa ribosomal protein S6 kinase 6) (p90-RSK 6) (Ribosomal S6 kinase 4) (RSK-4) (pp90RSK4).

KS6B1_HUMAN
θ value	θ > 10 (rank : 217)	NC score	0.060746 (rank : 203)
Query Neighborhood Hits	151	Target Neighborhood Hits	850	Shared Neighborhood Hits	32
SwissProt Accessions	P23443	Gene names	RPS6KB1
Domain Architecture
Description	Ribosomal protein S6 kinase beta-1 (EC 2.7.11.1) (Ribosomal protein S6 kinase I) (S6K) (S6K1) (70 kDa ribosomal protein S6 kinase 1) (p70 S6 kinase alpha) (p70(S6K)-alpha) (p70-S6K) (P70S6K) (p70-alpha).

KS6B1_MOUSE
θ value	θ > 10 (rank : 218)	NC score	0.060734 (rank : 204)
Query Neighborhood Hits	151	Target Neighborhood Hits	849	Shared Neighborhood Hits	32
SwissProt Accessions	Q8BSK8, Q8CHX0	Gene names	Rps6kb1
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase beta-1 (EC 2.7.11.1) (Ribosomal protein S6 kinase I) (S6K) (S6K1) (70 kDa ribosomal protein S6 kinase 1) (p70 S6 kinase alpha) (p70(S6K)-alpha) (p70-S6K) (P70S6K).

KS6B2_HUMAN
θ value	θ > 10 (rank : 219)	NC score	0.060675 (rank : 206)
Query Neighborhood Hits	151	Target Neighborhood Hits	858	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UBS0, O94809, Q9UEC1	Gene names	RPS6KB2, STK14B
Domain Architecture
Description	Ribosomal protein S6 kinase beta-2 (EC 2.7.11.1) (S6K2) (70 kDa ribosomal protein S6 kinase 2) (p70-S6KB) (p70 ribosomal S6 kinase beta) (p70 S6Kbeta) (p70 S6 kinase beta) (S6K-beta) (p70-beta) (S6 kinase-related kinase) (SRK) (Serine/threonine-protein kinase 14 beta).

KS6B2_MOUSE
θ value	θ > 10 (rank : 220)	NC score	0.061098 (rank : 202)
Query Neighborhood Hits	151	Target Neighborhood Hits	871	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Z1M4	Gene names	Rps6kb2
Domain Architecture
Description	Ribosomal protein S6 kinase beta-2 (EC 2.7.11.1) (S6K-beta 2) (70 kDa ribosomal protein S6 kinase 2) (p70-S6KB) (p70 ribosomal S6 kinase beta) (p70 S6Kbeta) (S6K2).

KS6C1_HUMAN
θ value	θ > 10 (rank : 221)	NC score	0.069169 (rank : 155)
Query Neighborhood Hits	151	Target Neighborhood Hits	682	Shared Neighborhood Hits	30
SwissProt Accessions	Q96S38, Q8TDD3, Q9NSF4, Q9UL66	Gene names	RPS6KC1, RPK118
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase delta-1 (EC 2.7.11.1) (52 kDa ribosomal protein S6 kinase) (Ribosomal S6 kinase-like protein with two PSK domains 118 kDa protein) (SPHK1-binding protein).

KS6C1_MOUSE
θ value	θ > 10 (rank : 222)	NC score	0.070308 (rank : 152)
Query Neighborhood Hits	151	Target Neighborhood Hits	700	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BLK9, Q3UDY3, Q6PDY4, Q8BMQ5, Q8BX49	Gene names	Rps6kc1
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase delta-1 (EC 2.7.11.1) (52 kDa ribosomal protein S6 kinase).

LATS1_HUMAN
θ value	θ > 10 (rank : 223)	NC score	0.065191 (rank : 170)
Query Neighborhood Hits	151	Target Neighborhood Hits	1057	Shared Neighborhood Hits	35
SwissProt Accessions	O95835, Q6PKD0	Gene names	LATS1, WARTS
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts).

LATS1_MOUSE
θ value	θ > 10 (rank : 224)	NC score	0.065469 (rank : 167)
Query Neighborhood Hits	151	Target Neighborhood Hits	1027	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BYR2, Q9Z0W4	Gene names	Lats1, Warts
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase).

LATS2_HUMAN
θ value	θ > 10 (rank : 225)	NC score	0.065022 (rank : 173)
Query Neighborhood Hits	151	Target Neighborhood Hits	884	Shared Neighborhood Hits	32
SwissProt Accessions	Q9NRM7, Q9P2X1	Gene names	LATS2, KPM
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Large tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Kinase phosphorylated during mitosis protein) (Warts-like kinase).

LATS2_MOUSE
θ value	θ > 10 (rank : 226)	NC score	0.065540 (rank : 166)
Query Neighborhood Hits	151	Target Neighborhood Hits	879	Shared Neighborhood Hits	32
SwissProt Accessions	Q7TSJ6, Q8CDJ4, Q9JMI3	Gene names	Lats2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Large tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Kinase phosphorylated during mitosis protein).

MAST1_HUMAN
θ value	θ > 10 (rank : 227)	NC score	0.059904 (rank : 213)
Query Neighborhood Hits	151	Target Neighborhood Hits	1146	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

MAST1_MOUSE
θ value	θ > 10 (rank : 228)	NC score	0.059745 (rank : 215)
Query Neighborhood Hits	151	Target Neighborhood Hits	1123	Shared Neighborhood Hits	33
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

MAST2_HUMAN
θ value	θ > 10 (rank : 229)	NC score	0.058491 (rank : 222)
Query Neighborhood Hits	151	Target Neighborhood Hits	1189	Shared Neighborhood Hits	35
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

MAST2_MOUSE
θ value	θ > 10 (rank : 230)	NC score	0.058361 (rank : 223)
Query Neighborhood Hits	151	Target Neighborhood Hits	1110	Shared Neighborhood Hits	34
SwissProt Accessions	Q60592, Q6P9M1, Q8CHD1	Gene names	Mast2, Mast205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

MAST3_HUMAN
θ value	θ > 10 (rank : 231)	NC score	0.059306 (rank : 220)
Query Neighborhood Hits	151	Target Neighborhood Hits	1128	Shared Neighborhood Hits	34
SwissProt Accessions	O60307, Q7LDZ8, Q9UPI0	Gene names	MAST3, KIAA0561
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1).

MAST4_HUMAN
θ value	θ > 10 (rank : 232)	NC score	0.058258 (rank : 224)
Query Neighborhood Hits	151	Target Neighborhood Hits	1804	Shared Neighborhood Hits	39
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

MASTL_HUMAN
θ value	θ > 10 (rank : 233)	NC score	0.057617 (rank : 233)
Query Neighborhood Hits	151	Target Neighborhood Hits	894	Shared Neighborhood Hits	32
SwissProt Accessions	Q96GX5, Q5T8D5, Q5T8D7, Q8NCD6, Q96SJ5	Gene names	MASTL, THC2
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase-like (EC 2.7.11.1).

MASTL_MOUSE
θ value	θ > 10 (rank : 234)	NC score	0.057308 (rank : 235)
Query Neighborhood Hits	151	Target Neighborhood Hits	862	Shared Neighborhood Hits	32
SwissProt Accessions	Q8C0P0, Q5RJW0, Q6NXX9, Q8BVF3, Q9CZH9, Q9D9V0	Gene names	Mastl
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase-like (EC 2.7.11.1).

MCFD2_HUMAN
θ value	θ > 10 (rank : 235)	NC score	0.071570 (rank : 149)
Query Neighborhood Hits	151	Target Neighborhood Hits	62	Shared Neighborhood Hits	33
SwissProt Accessions	Q8NI22, Q8N3M5	Gene names	MCFD2, SDNSF
Domain Architecture
Description	Multiple coagulation factor deficiency protein 2 precursor (Neural stem cell-derived neuronal survival protein).

MCFD2_MOUSE
θ value	θ > 10 (rank : 236)	NC score	0.068347 (rank : 158)
Query Neighborhood Hits	151	Target Neighborhood Hits	61	Shared Neighborhood Hits	31
SwissProt Accessions	Q8K5B2, Q3U9G5	Gene names	Mcfd2, Sdnsf
Domain Architecture
Description	Multiple coagulation factor deficiency protein 2 homolog precursor (Neural stem cell-derived neuronal survival protein).

ONCO_HUMAN
θ value	θ > 10 (rank : 237)	NC score	0.068942 (rank : 156)
Query Neighborhood Hits	151	Target Neighborhood Hits	88	Shared Neighborhood Hits	36
SwissProt Accessions	P32930	Gene names	OCM, OCMN
Domain Architecture
Description	Oncomodulin (OM) (Parvalbumin beta).

ONCO_MOUSE
θ value	θ > 10 (rank : 238)	NC score	0.069808 (rank : 154)
Query Neighborhood Hits	151	Target Neighborhood Hits	98	Shared Neighborhood Hits	43
SwissProt Accessions	P51879, Q62004	Gene names	Ocm
Domain Architecture
Description	Oncomodulin (OM) (Parvalbumin beta).

PCAT1_MOUSE
θ value	θ > 10 (rank : 239)	NC score	0.073985 (rank : 146)
Query Neighborhood Hits	151	Target Neighborhood Hits	78	Shared Neighborhood Hits	47
SwissProt Accessions	Q3TFD2, Q3TAX4, Q6NXZ6, Q8BG23, Q8BUX7, Q99JU6	Gene names	Aytl2, Lpcat1
Domain Architecture	No domain graphic available
Description	1-acylglycerophosphocholine O-acyltransferase 1 (EC 2.3.1.23) (Lung- type acyl-coa:lysophosphatidylcholine acyltransferase 1) (mLPCAT1) (Acyltransferase-like 2).

PDCD6_HUMAN
θ value	θ > 10 (rank : 240)	NC score	0.062669 (rank : 190)
Query Neighborhood Hits	151	Target Neighborhood Hits	141	Shared Neighborhood Hits	51
SwissProt Accessions	O75340	Gene names	PDCD6, ALG2
Domain Architecture
Description	Programmed cell death protein 6 (Probable calcium-binding protein ALG- 2).

PDCD6_MOUSE
θ value	θ > 10 (rank : 241)	NC score	0.062995 (rank : 189)
Query Neighborhood Hits	151	Target Neighborhood Hits	142	Shared Neighborhood Hits	51
SwissProt Accessions	P12815, Q545I0, Q61145	Gene names	Pdcd6, Alg2
Domain Architecture
Description	Programmed cell death protein 6 (Probable calcium-binding protein ALG- 2) (PMP41) (ALG-257).

PDPK1_HUMAN
θ value	θ > 10 (rank : 242)	NC score	0.054433 (rank : 259)
Query Neighborhood Hits	151	Target Neighborhood Hits	851	Shared Neighborhood Hits	32
SwissProt Accessions	O15530	Gene names	PDPK1, PDK1
Domain Architecture
Description	3-phosphoinositide-dependent protein kinase 1 (EC 2.7.11.1) (hPDK1).

PDPK1_MOUSE
θ value	θ > 10 (rank : 243)	NC score	0.054575 (rank : 256)
Query Neighborhood Hits	151	Target Neighborhood Hits	852	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Z2A0, Q9R1D8, Q9R215	Gene names	Pdpk1, Pdk1
Domain Architecture
Description	3-phosphoinositide-dependent protein kinase 1 (EC 2.7.11.1) (mPDK1).

PDZD8_HUMAN
θ value	θ > 10 (rank : 244)	NC score	0.146432 (rank : 67)
Query Neighborhood Hits	151	Target Neighborhood Hits	185	Shared Neighborhood Hits	51
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

PKN1_HUMAN
θ value	θ > 10 (rank : 245)	NC score	0.065935 (rank : 163)
Query Neighborhood Hits	151	Target Neighborhood Hits	886	Shared Neighborhood Hits	33
SwissProt Accessions	Q16512, Q15143, Q8IUV5	Gene names	PKN1, PKN, PRK1, PRKCL1
Domain Architecture
Description	Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protein kinase C- like 1) (Protein-kinase C-related kinase 1) (Protein kinase C-like PKN) (Serine-threonine protein kinase N) (Protein kinase PKN-alpha).

PKN1_MOUSE
θ value	θ > 10 (rank : 246)	NC score	0.065979 (rank : 162)
Query Neighborhood Hits	151	Target Neighborhood Hits	888	Shared Neighborhood Hits	32
SwissProt Accessions	P70268, Q7TST2	Gene names	Pkn1, Pkn, Prk1, Prkcl1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protein kinase C- like 1) (Protein-kinase C-related kinase 1) (Protein kinase C-like PKN) (Serine-threonine protein kinase N).

PKN2_HUMAN
θ value	θ > 10 (rank : 247)	NC score	0.065290 (rank : 169)
Query Neighborhood Hits	151	Target Neighborhood Hits	892	Shared Neighborhood Hits	32
SwissProt Accessions	Q16513, Q9H1W4	Gene names	PKN2, PRK2, PRKCL2
Domain Architecture
Description	Serine/threonine-protein kinase N2 (EC 2.7.11.13) (Protein kinase C- like 2) (Protein-kinase C-related kinase 2).

PKN2_MOUSE
θ value	θ > 10 (rank : 248)	NC score	0.065160 (rank : 171)
Query Neighborhood Hits	151	Target Neighborhood Hits	899	Shared Neighborhood Hits	32
SwissProt Accessions	Q8BWW9, Q80WS2, Q8BJL7	Gene names	Pkn2, Prkcl2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N2 (EC 2.7.11.13) (Protein kinase C- like 2) (Protein-kinase C-related kinase 2).

PKN3_HUMAN
θ value	θ > 10 (rank : 249)	NC score	0.065811 (rank : 164)
Query Neighborhood Hits	151	Target Neighborhood Hits	893	Shared Neighborhood Hits	33
SwissProt Accessions	Q6P5Z2, Q9UM03	Gene names	PKN3, PKNBETA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein kinase PKN- beta) (Protein-kinase C-related kinase 3).

PKN3_MOUSE
θ value	θ > 10 (rank : 250)	NC score	0.064752 (rank : 175)
Query Neighborhood Hits	151	Target Neighborhood Hits	1009	Shared Neighborhood Hits	32
SwissProt Accessions	Q8K045	Gene names	Pkn3, Pknbeta
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein kinase PKN- beta) (Protein-kinase C-related kinase 3).

PRKX_HUMAN
θ value	θ > 10 (rank : 251)	NC score	0.057806 (rank : 231)
Query Neighborhood Hits	151	Target Neighborhood Hits	847	Shared Neighborhood Hits	32
SwissProt Accessions	P51817	Gene names	PRKX, PKX1
Domain Architecture
Description	Serine/threonine-protein kinase PRKX (EC 2.7.11.1) (Protein kinase PKX1).

PRKX_MOUSE
θ value	θ > 10 (rank : 252)	NC score	0.057842 (rank : 230)
Query Neighborhood Hits	151	Target Neighborhood Hits	846	Shared Neighborhood Hits	32
SwissProt Accessions	Q922R0, Q3UCD1, Q8BHD6, Q9QZ12	Gene names	Prkx, Pkare
Domain Architecture
Description	Serine/threonine-protein kinase PRKX (EC 2.7.11.1) (PKA-related protein kinase).

PRKY_HUMAN
θ value	θ > 10 (rank : 253)	NC score	0.054227 (rank : 262)
Query Neighborhood Hits	151	Target Neighborhood Hits	844	Shared Neighborhood Hits	32
SwissProt Accessions	O43930, O15348, O15349	Gene names	PRKY
Domain Architecture
Description	Serine/threonine-protein kinase PRKY (EC 2.7.11.1).

PRVA_MOUSE
θ value	θ > 10 (rank : 254)	NC score	0.059448 (rank : 219)
Query Neighborhood Hits	151	Target Neighborhood Hits	77	Shared Neighborhood Hits	33
SwissProt Accessions	P32848	Gene names	Pvalb, Pva
Domain Architecture
Description	Parvalbumin alpha.

RASF1_HUMAN
θ value	θ > 10 (rank : 255)	NC score	0.136397 (rank : 71)
Query Neighborhood Hits	151	Target Neighborhood Hits	62	Shared Neighborhood Hits	48
SwissProt Accessions	Q9NS23, O14571, O60539, O60710, Q9HB04, Q9HB18, Q9NS22, Q9UND4, Q9UND5	Gene names	RASSF1, RDA32
Domain Architecture	No domain graphic available
Description	Ras association domain-containing protein 1.

RK_HUMAN
θ value	θ > 10 (rank : 256)	NC score	0.061493 (rank : 199)
Query Neighborhood Hits	151	Target Neighborhood Hits	835	Shared Neighborhood Hits	32
SwissProt Accessions	Q15835	Gene names	GRK1, RHOK
Domain Architecture
Description	Rhodopsin kinase precursor (EC 2.7.11.14) (RK) (G protein-coupled receptor kinase 1).

RK_MOUSE
θ value	θ > 10 (rank : 257)	NC score	0.059459 (rank : 218)
Query Neighborhood Hits	151	Target Neighborhood Hits	829	Shared Neighborhood Hits	32
SwissProt Accessions	Q9WVL4	Gene names	Grk1, Rhok
Domain Architecture
Description	Rhodopsin kinase precursor (EC 2.7.11.14) (RK) (G protein-coupled receptor kinase 1).

ROCK1_HUMAN
θ value	θ > 10 (rank : 258)	NC score	0.056534 (rank : 241)
Query Neighborhood Hits	151	Target Neighborhood Hits	2000	Shared Neighborhood Hits	48
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).

ROCK1_MOUSE
θ value	θ > 10 (rank : 259)	NC score	0.055177 (rank : 249)
Query Neighborhood Hits	151	Target Neighborhood Hits	2126	Shared Neighborhood Hits	48
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

ROCK2_HUMAN
θ value	θ > 10 (rank : 260)	NC score	0.056902 (rank : 238)
Query Neighborhood Hits	151	Target Neighborhood Hits	2073	Shared Neighborhood Hits	47
SwissProt Accessions	O75116, Q9UQN5	Gene names	ROCK2, KIAA0619
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2).

ROCK2_MOUSE
θ value	θ > 10 (rank : 261)	NC score	0.056946 (rank : 237)
Query Neighborhood Hits	151	Target Neighborhood Hits	2072	Shared Neighborhood Hits	49
SwissProt Accessions	P70336, Q8BR64, Q8CBR0	Gene names	Rock2
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2).

RPKL1_HUMAN
θ value	θ > 10 (rank : 262)	NC score	0.073615 (rank : 147)
Query Neighborhood Hits	151	Target Neighborhood Hits	708	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Y6S9, Q69YT9, Q6ZMQ6, Q96NR9, Q9BSU9	Gene names	RPS6KL1
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase-like 1 (EC 2.7.11.1).

RPKL1_MOUSE
θ value	θ > 10 (rank : 263)	NC score	0.073146 (rank : 148)
Query Neighborhood Hits	151	Target Neighborhood Hits	704	Shared Neighborhood Hits	32
SwissProt Accessions	Q8R2S1, Q8R1D4	Gene names	Rps6kl1
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase-like 1 (EC 2.7.11.1).

SEGN_MOUSE
θ value	θ > 10 (rank : 264)	NC score	0.067830 (rank : 159)
Query Neighborhood Hits	151	Target Neighborhood Hits	101	Shared Neighborhood Hits	41
SwissProt Accessions	Q91WD9	Gene names	Scgn
Domain Architecture
Description	Secretagogin.

SGK1_HUMAN
θ value	θ > 10 (rank : 265)	NC score	0.064044 (rank : 182)
Query Neighborhood Hits	151	Target Neighborhood Hits	848	Shared Neighborhood Hits	32
SwissProt Accessions	O00141, Q5TCN3, Q9UN56	Gene names	SGK, SGK1
Domain Architecture
Description	Serine/threonine-protein kinase Sgk1 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 1).

SGK1_MOUSE
θ value	θ > 10 (rank : 266)	NC score	0.064210 (rank : 179)
Query Neighborhood Hits	151	Target Neighborhood Hits	848	Shared Neighborhood Hits	32
SwissProt Accessions	Q9WVC6	Gene names	Sgk, Sgk1
Domain Architecture
Description	Serine/threonine-protein kinase Sgk1 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 1).

SGK2_HUMAN
θ value	θ > 10 (rank : 267)	NC score	0.065125 (rank : 172)
Query Neighborhood Hits	151	Target Neighborhood Hits	840	Shared Neighborhood Hits	32
SwissProt Accessions	Q9HBY8, Q9UKG6	Gene names	SGK2
Domain Architecture
Description	Serine/threonine-protein kinase Sgk2 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 2).

SGK2_MOUSE
θ value	θ > 10 (rank : 268)	NC score	0.064547 (rank : 176)
Query Neighborhood Hits	151	Target Neighborhood Hits	833	Shared Neighborhood Hits	32
SwissProt Accessions	Q9QZS5, Q8R0P6	Gene names	Sgk2
Domain Architecture
Description	Serine/threonine-protein kinase Sgk2 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 2).

SGK3_HUMAN
θ value	θ > 10 (rank : 269)	NC score	0.064226 (rank : 178)
Query Neighborhood Hits	151	Target Neighborhood Hits	877	Shared Neighborhood Hits	32
SwissProt Accessions	Q96BR1, Q9P1Q7, Q9UKG5	Gene names	SGK3, SGKL
Domain Architecture
Description	Serine/threonine-protein kinase Sgk3 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 3) (Serum/glucocorticoid- regulated kinase-like).

SGK3_MOUSE
θ value	θ > 10 (rank : 270)	NC score	0.064019 (rank : 183)
Query Neighborhood Hits	151	Target Neighborhood Hits	882	Shared Neighborhood Hits	32
SwissProt Accessions	Q9ERE3, Q3UAY2	Gene names	Sgk3, Cisk, Sgkl
Domain Architecture
Description	Serine/threonine-protein kinase Sgk3 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 3) (Serum/glucocorticoid- regulated kinase-like) (Cytokine-independent survival kinase).

ST32A_HUMAN
θ value	θ > 10 (rank : 271)	NC score	0.056103 (rank : 243)
Query Neighborhood Hits	151	Target Neighborhood Hits	834	Shared Neighborhood Hits	32
SwissProt Accessions	Q8WU08	Gene names	STK32A
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 32A (EC 2.7.11.1) (YANK1).

ST32A_MOUSE
θ value	θ > 10 (rank : 272)	NC score	0.055185 (rank : 248)
Query Neighborhood Hits	151	Target Neighborhood Hits	833	Shared Neighborhood Hits	32
SwissProt Accessions	Q8BGW6, Q7TPQ4	Gene names	Stk32a
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 32A (EC 2.7.11.1).

ST32B_HUMAN
θ value	θ > 10 (rank : 273)	NC score	0.056993 (rank : 236)
Query Neighborhood Hits	151	Target Neighborhood Hits	830	Shared Neighborhood Hits	32
SwissProt Accessions	Q9NY57, Q6UXH3, Q8IY14	Gene names	STK32B
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 32B (EC 2.7.11.1) (YANK2).

ST32B_MOUSE
θ value	θ > 10 (rank : 274)	NC score	0.056638 (rank : 240)
Query Neighborhood Hits	151	Target Neighborhood Hits	828	Shared Neighborhood Hits	32
SwissProt Accessions	Q9JJX8, Q7TMD3, Q8C4E0	Gene names	Stk32b, Stk32
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 32B (EC 2.7.11.1).

ST32C_HUMAN
θ value	θ > 10 (rank : 275)	NC score	0.058112 (rank : 227)
Query Neighborhood Hits	151	Target Neighborhood Hits	832	Shared Neighborhood Hits	32
SwissProt Accessions	Q86UX6, Q5T0Q5, Q86UE1	Gene names	STK32C
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 32C (EC 2.7.11.1) (PKE) (YANK3).

ST32C_MOUSE
θ value	θ > 10 (rank : 276)	NC score	0.057706 (rank : 232)
Query Neighborhood Hits	151	Target Neighborhood Hits	824	Shared Neighborhood Hits	32
SwissProt Accessions	Q8QZV4, Q9JJG4	Gene names	Stk32c, Pkek
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 32C (EC 2.7.11.1).

ST38L_HUMAN
θ value	θ > 10 (rank : 277)	NC score	0.064313 (rank : 177)
Query Neighborhood Hits	151	Target Neighborhood Hits	824	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Y2H1, Q8TBX7	Gene names	STK38L, KIAA0965, NDR2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 38-like (EC 2.7.11.1) (NDR2 protein kinase) (Nuclear Dbf2-related kinase 2).

ST38L_MOUSE
θ value	θ > 10 (rank : 278)	NC score	0.064977 (rank : 174)
Query Neighborhood Hits	151	Target Neighborhood Hits	821	Shared Neighborhood Hits	33
SwissProt Accessions	Q7TSE6, Q6P6K6, Q8BWK4	Gene names	Stk38l, Ndr2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 38-like (EC 2.7.11.1) (NDR2 protein kinase) (Nuclear Dbf2-related kinase 2).

STK38_HUMAN
θ value	θ > 10 (rank : 279)	NC score	0.064104 (rank : 180)
Query Neighborhood Hits	151	Target Neighborhood Hits	840	Shared Neighborhood Hits	32
SwissProt Accessions	Q15208	Gene names	STK38, NDR1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 38 (EC 2.7.11.1) (NDR1 protein kinase) (Nuclear Dbf2-related kinase 1).

STK38_MOUSE
θ value	θ > 10 (rank : 280)	NC score	0.064064 (rank : 181)
Query Neighborhood Hits	151	Target Neighborhood Hits	838	Shared Neighborhood Hits	32
SwissProt Accessions	Q91VJ4	Gene names	Stk38, Ndr1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 38 (EC 2.7.11.1) (NDR1 protein kinase) (Nuclear Dbf2-related kinase 1).

STK40_HUMAN
θ value	θ > 10 (rank : 281)	NC score	0.051871 (rank : 267)
Query Neighborhood Hits	151	Target Neighborhood Hits	751	Shared Neighborhood Hits	32
SwissProt Accessions	Q8N2I9, Q5VTK8, Q5VTK9, Q6ZMN1, Q8N2J8, Q8N3I6, Q96HN6, Q96I44, Q9BSA3, Q9H7H6	Gene names	STK40, SHIK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 40 (EC 2.7.11.1) (SINK-homologous serine/threonine-protein kinase).

STK40_MOUSE
θ value	θ > 10 (rank : 282)	NC score	0.052135 (rank : 266)
Query Neighborhood Hits	151	Target Neighborhood Hits	751	Shared Neighborhood Hits	32
SwissProt Accessions	Q7TNL3, Q3U3G3, Q811D6, Q8BKT1, Q9D7K3	Gene names	Stk40, Lyk4
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 40 (EC 2.7.11.1) (Serine/threonine- protein kinase lyk4).

TESC_HUMAN
θ value	θ > 10 (rank : 283)	NC score	0.112187 (rank : 97)
Query Neighborhood Hits	151	Target Neighborhood Hits	64	Shared Neighborhood Hits	40
SwissProt Accessions	Q96BS2	Gene names	TESC
Domain Architecture	No domain graphic available
Description	Tescalcin (TSC).

TESC_MOUSE
θ value	θ > 10 (rank : 284)	NC score	0.109771 (rank : 100)
Query Neighborhood Hits	151	Target Neighborhood Hits	63	Shared Neighborhood Hits	39
SwissProt Accessions	Q9JKL5	Gene names	Tesc
Domain Architecture	No domain graphic available
Description	Tescalcin (TSC).

TNNC1_HUMAN
θ value	θ > 10 (rank : 285)	NC score	0.107099 (rank : 104)
Query Neighborhood Hits	151	Target Neighborhood Hits	219	Shared Neighborhood Hits	63
SwissProt Accessions	P63316, O14800, P02590, P04463	Gene names	TNNC1, TNNC
Domain Architecture	No domain graphic available
Description	Troponin C, slow skeletal and cardiac muscles (TN-C).

TNNC1_MOUSE
θ value	θ > 10 (rank : 286)	NC score	0.106615 (rank : 107)
Query Neighborhood Hits	151	Target Neighborhood Hits	221	Shared Neighborhood Hits	63
SwissProt Accessions	P19123	Gene names	Tnnc1, Tncc
Domain Architecture
Description	Troponin C, slow skeletal and cardiac muscles (TN-C).

TNNC2_HUMAN
θ value	θ > 10 (rank : 287)	NC score	0.100968 (rank : 120)
Query Neighborhood Hits	151	Target Neighborhood Hits	234	Shared Neighborhood Hits	62
SwissProt Accessions	P02585	Gene names	TNNC2
Domain Architecture
Description	Troponin C, skeletal muscle.

TNNC2_MOUSE
θ value	θ > 10 (rank : 288)	NC score	0.102285 (rank : 118)
Query Neighborhood Hits	151	Target Neighborhood Hits	233	Shared Neighborhood Hits	61
SwissProt Accessions	P20801	Gene names	Tnnc2, Tncs
Domain Architecture
Description	Troponin C, skeletal muscle (STNC).

TRIB1_HUMAN
θ value	θ > 10 (rank : 289)	NC score	0.051271 (rank : 270)
Query Neighborhood Hits	151	Target Neighborhood Hits	598	Shared Neighborhood Hits	32
SwissProt Accessions	Q96RU8, O15180, Q9H2Y8	Gene names	TRIB1, C8FW, GIG2, TRB1
Domain Architecture	No domain graphic available
Description	Tribbles homolog 1 (TRB-1) (SKIP1) (G-protein-coupled receptor-induced protein 2) (GIG-2).

TRIB1_MOUSE
θ value	θ > 10 (rank : 290)	NC score	0.050561 (rank : 272)
Query Neighborhood Hits	151	Target Neighborhood Hits	593	Shared Neighborhood Hits	32
SwissProt Accessions	Q8K4K4, Q8BFS7, Q8BJR9, Q8BZX3, Q91W04	Gene names	Trib1, Trb1
Domain Architecture	No domain graphic available
Description	Tribbles homolog 1 (TRB-1).

TRIB3_HUMAN
θ value	θ > 10 (rank : 291)	NC score	0.052590 (rank : 265)
Query Neighborhood Hits	151	Target Neighborhood Hits	519	Shared Neighborhood Hits	29
SwissProt Accessions	Q96RU7, Q53GU4, Q53ZW7, Q6I9Y9, Q8TAI6, Q9H5M8, Q9NUD2	Gene names	TRIB3, C20orf97, NIPK, SKIP3, TRB3
Domain Architecture
Description	Tribbles homolog 3 (TRB-3) (Neuronal cell death-inducible putative kinase) (p65-interacting inhibitor of NF-kappaB) (SINK).

TRIB3_MOUSE
θ value	θ > 10 (rank : 292)	NC score	0.051370 (rank : 269)
Query Neighborhood Hits	151	Target Neighborhood Hits	578	Shared Neighborhood Hits	30
SwissProt Accessions	Q8K4K2, Q3UMQ0, Q921E7	Gene names	Trib3, Nipk, Trb3
Domain Architecture
Description	Tribbles homolog 3 (TRB-3) (Neuronal cell death-inducible putative kinase).

ULK4_MOUSE
θ value	θ > 10 (rank : 293)	NC score	0.050533 (rank : 273)
Query Neighborhood Hits	151	Target Neighborhood Hits	793	Shared Neighborhood Hits	32
SwissProt Accessions	Q3V129, Q2VP87, Q32LZ6, Q8BLS0, Q8C8Z5, Q9D4H6	Gene names	Ulk4
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK4 (EC 2.7.11.1) (Unc-51-like kinase 4).

VAV2_HUMAN
θ value	θ > 10 (rank : 294)	NC score	0.066024 (rank : 161)
Query Neighborhood Hits	151	Target Neighborhood Hits	453	Shared Neighborhood Hits	49
SwissProt Accessions	P52735	Gene names	VAV2
Domain Architecture
Description	Protein vav-2.

VAV2_MOUSE
θ value	θ > 10 (rank : 295)	NC score	0.062194 (rank : 191)
Query Neighborhood Hits	151	Target Neighborhood Hits	456	Shared Neighborhood Hits	47
SwissProt Accessions	Q60992	Gene names	Vav2
Domain Architecture
Description	Protein vav-2.

VAV_HUMAN
θ value	θ > 10 (rank : 296)	NC score	0.056718 (rank : 239)
Query Neighborhood Hits	151	Target Neighborhood Hits	452	Shared Neighborhood Hits	50
SwissProt Accessions	P15498, Q15860	Gene names	VAV1, VAV
Domain Architecture
Description	Proto-oncogene vav.

VAV_MOUSE
θ value	θ > 10 (rank : 297)	NC score	0.053344 (rank : 264)
Query Neighborhood Hits	151	Target Neighborhood Hits	430	Shared Neighborhood Hits	48
SwissProt Accessions	P27870, Q8BTV7	Gene names	Vav1, Vav
Domain Architecture
Description	Proto-oncogene vav (p95vav).

VISL1_HUMAN
θ value	θ > 10 (rank : 298)	NC score	0.188193 (rank : 53)
Query Neighborhood Hits	151	Target Neighborhood Hits	124	Shared Neighborhood Hits	62
SwissProt Accessions	P62760, P28677, P29103, P42323, Q9UM20	Gene names	VSNL1, VISL1
Domain Architecture	No domain graphic available
Description	Visinin-like protein 1 (VILIP) (Hippocalcin-like protein 3) (HLP3).

VISL1_MOUSE
θ value	θ > 10 (rank : 299)	NC score	0.188193 (rank : 54)
Query Neighborhood Hits	151	Target Neighborhood Hits	124	Shared Neighborhood Hits	62
SwissProt Accessions	P62761, P28677, P29103, P42323, Q9UM20	Gene names	Vsnl1, Visl1
Domain Architecture	No domain graphic available
Description	Visinin-like protein 1 (VILIP) (Neural visinin-like protein 1) (NVL-1) (NVP-1).

Hits sorted by NC score

DGKA_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	151	Target Neighborhood Hits	151	Shared Neighborhood Hits	151
SwissProt Accessions	P23743, O75481, O75482, O75483	Gene names	DGKA, DAGK, DAGK1
Domain Architecture
Description	Diacylglycerol kinase alpha (EC 2.7.1.107) (Diglyceride kinase alpha) (DGK-alpha) (DAG kinase alpha) (80 kDa diacylglycerol kinase).

DGKA_MOUSE
NC score	0.982097 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	151	Target Neighborhood Hits	146	Shared Neighborhood Hits	114
SwissProt Accessions	O88673, Q922X2	Gene names	Dgka, Dagk1
Domain Architecture
Description	Diacylglycerol kinase alpha (EC 2.7.1.107) (Diglyceride kinase alpha) (DGK-alpha) (DAG kinase alpha) (80 kDa diacylglycerol kinase).

DGKG_HUMAN
NC score	0.970963 (rank : 3)	θ value	0 (rank : 4)
Query Neighborhood Hits	151	Target Neighborhood Hits	171	Shared Neighborhood Hits	108
SwissProt Accessions	P49619	Gene names	DGKG, DAGK3
Domain Architecture
Description	Diacylglycerol kinase gamma (EC 2.7.1.107) (Diglyceride kinase gamma) (DGK-gamma) (DAG kinase gamma).

DGKG_MOUSE
NC score	0.970343 (rank : 4)	θ value	0 (rank : 5)
Query Neighborhood Hits	151	Target Neighborhood Hits	188	Shared Neighborhood Hits	110
SwissProt Accessions	Q91WG7	Gene names	Dgkg, Dagk3
Domain Architecture
Description	Diacylglycerol kinase gamma (EC 2.7.1.107) (Diglyceride kinase gamma) (DGK-gamma) (DAG kinase gamma) (88 kDa diacylglycerol kinase).

DGKB_HUMAN
NC score	0.959154 (rank : 5)	θ value	0 (rank : 3)
Query Neighborhood Hits	151	Target Neighborhood Hits	238	Shared Neighborhood Hits	123
SwissProt Accessions	Q9Y6T7, O75241, Q75MF9, Q75MU7, Q86UI5, Q86UM9, Q9UQ29	Gene names	DGKB, DAGK2, KIAA0718
Domain Architecture
Description	Diacylglycerol kinase beta (EC 2.7.1.107) (Diglyceride kinase beta) (DGK-beta) (DAG kinase beta) (90 kDa diacylglycerol kinase).

DGKE_HUMAN
NC score	0.893616 (rank : 6)	θ value	4.67263e-73 (rank : 6)
Query Neighborhood Hits	151	Target Neighborhood Hits	32	Shared Neighborhood Hits	25
SwissProt Accessions	P52429, Q9UKQ3	Gene names	DGKE, DAGK5
Domain Architecture
Description	Diacylglycerol kinase epsilon (EC 2.7.1.107) (Diglyceride kinase epsilon) (DGK-epsilon) (DAG kinase epsilon).

DGKE_MOUSE
NC score	0.892328 (rank : 7)	θ value	6.10265e-73 (rank : 7)
Query Neighborhood Hits	151	Target Neighborhood Hits	30	Shared Neighborhood Hits	24
SwissProt Accessions	Q9R1C6	Gene names	Dgke
Domain Architecture
Description	Diacylglycerol kinase epsilon (EC 2.7.1.107) (Diglyceride kinase epsilon) (DGK-epsilon) (DAG kinase epsilon).

DGKQ_HUMAN
NC score	0.879516 (rank : 8)	θ value	1.08223e-53 (rank : 11)
Query Neighborhood Hits	151	Target Neighborhood Hits	131	Shared Neighborhood Hits	67
SwissProt Accessions	P52824	Gene names	DGKQ, DAGK4
Domain Architecture
Description	Diacylglycerol kinase theta (EC 2.7.1.107) (Diglyceride kinase theta) (DGK-theta) (DAG kinase theta).

DGKD_HUMAN
NC score	0.796114 (rank : 9)	θ value	7.01481e-53 (rank : 12)
Query Neighborhood Hits	151	Target Neighborhood Hits	231	Shared Neighborhood Hits	62
SwissProt Accessions	Q16760, Q14158, Q6PK55, Q8NG53	Gene names	DGKD, KIAA0145
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase delta (EC 2.7.1.107) (Diglyceride kinase delta) (DGK-delta) (DAG kinase delta) (130 kDa diacylglycerol kinase).

DGKH_HUMAN
NC score	0.790582 (rank : 10)	θ value	1.19655e-52 (rank : 13)
Query Neighborhood Hits	151	Target Neighborhood Hits	255	Shared Neighborhood Hits	62
SwissProt Accessions	Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9	Gene names	DGKH
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).

DGKZ_MOUSE
NC score	0.739273 (rank : 11)	θ value	3.95564e-72 (rank : 8)
Query Neighborhood Hits	151	Target Neighborhood Hits	542	Shared Neighborhood Hits	18
SwissProt Accessions	Q80UP3	Gene names	Dgkz
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

DGKK_HUMAN
NC score	0.739081 (rank : 12)	θ value	1.36902e-48 (rank : 14)
Query Neighborhood Hits	151	Target Neighborhood Hits	378	Shared Neighborhood Hits	41
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

DGKZ_HUMAN
NC score	0.734863 (rank : 13)	θ value	2.56397e-71 (rank : 10)
Query Neighborhood Hits	151	Target Neighborhood Hits	551	Shared Neighborhood Hits	17
SwissProt Accessions	Q13574, O00542	Gene names	DGKZ, DAGK6
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

DGKI_HUMAN
NC score	0.727088 (rank : 14)	θ value	5.1662e-72 (rank : 9)
Query Neighborhood Hits	151	Target Neighborhood Hits	609	Shared Neighborhood Hits	18
SwissProt Accessions	O75912, Q9NZ49	Gene names	DGKI
Domain Architecture
Description	Diacylglycerol kinase iota (EC 2.7.1.107) (Diglyceride kinase iota) (DGK-iota) (DAG kinase iota).

KIP1_MOUSE
NC score	0.273545 (rank : 15)	θ value	0.00102713 (rank : 35)
Query Neighborhood Hits	151	Target Neighborhood Hits	109	Shared Neighborhood Hits	56
SwissProt Accessions	Q9Z0F4, Q3TN80	Gene names	Cib1, Cib, Kip, Prkdcip
Domain Architecture
Description	Calcium and integrin-binding protein 1 (Calmyrin) (DNA-PKcs- interacting protein) (Kinase-interacting protein) (KIP) (CIB).

KIP1_HUMAN
NC score	0.261789 (rank : 16)	θ value	0.00509761 (rank : 51)
Query Neighborhood Hits	151	Target Neighborhood Hits	105	Shared Neighborhood Hits	56
SwissProt Accessions	Q99828, O00693, O00735, Q6IB49, Q96J54, Q99971	Gene names	CIB1, CIB, KIP, PRKDCIP
Domain Architecture
Description	Calcium and integrin-binding protein 1 (Calmyrin) (DNA-PKcs- interacting protein) (Kinase-interacting protein) (KIP) (CIB) (SNK- interacting protein 2-28) (SIP2-28).

GUC1A_MOUSE
NC score	0.240298 (rank : 17)	θ value	0.000461057 (rank : 29)
Query Neighborhood Hits	151	Target Neighborhood Hits	152	Shared Neighborhood Hits	67
SwissProt Accessions	P43081	Gene names	Guca1a, Gcap, Gcap1, Guca1
Domain Architecture
Description	Guanylyl cyclase-activating protein 1 (GCAP 1) (Guanylate cyclase activator 1A).

GUC1A_HUMAN
NC score	0.238712 (rank : 18)	θ value	0.00102713 (rank : 33)
Query Neighborhood Hits	151	Target Neighborhood Hits	147	Shared Neighborhood Hits	67
SwissProt Accessions	P43080, Q9NU14	Gene names	GUCA1A, GCAP, GCAP1, GUCA1
Domain Architecture
Description	Guanylyl cyclase-activating protein 1 (GCAP 1) (Guanylate cyclase activator 1A).

CANB2_MOUSE
NC score	0.234213 (rank : 19)	θ value	0.000602161 (rank : 31)
Query Neighborhood Hits	151	Target Neighborhood Hits	173	Shared Neighborhood Hits	68
SwissProt Accessions	Q63811	Gene names	Ppp3r2
Domain Architecture
Description	Calcineurin subunit B isoform 2 (Protein phosphatase 2B regulatory subunit 2) (Protein phosphatase 3 regulatory subunit B beta isoform).

CHP2_MOUSE
NC score	0.229400 (rank : 20)	θ value	0.000461057 (rank : 28)
Query Neighborhood Hits	151	Target Neighborhood Hits	122	Shared Neighborhood Hits	62
SwissProt Accessions	Q9D869	Gene names	Chp2, Hca520
Domain Architecture
Description	Calcineurin B homologous protein 2 (Hepatocellular carcinoma- associated antigen 520 homolog).

CANB2_HUMAN
NC score	0.228586 (rank : 21)	θ value	0.000786445 (rank : 32)
Query Neighborhood Hits	151	Target Neighborhood Hits	163	Shared Neighborhood Hits	66
SwissProt Accessions	Q96LZ3, Q7Z4V8, Q8WYJ4	Gene names	PPP3R2, CBLP
Domain Architecture	No domain graphic available
Description	Calcineurin subunit B isoform 2 (Protein phosphatase 2B regulatory subunit 2) (Protein phosphatase 3 regulatory subunit B beta isoform) (Calcineurin B-like protein) (CBLP) (CNBII).

CANB1_HUMAN
NC score	0.227556 (rank : 22)	θ value	0.00665767 (rank : 53)
Query Neighborhood Hits	151	Target Neighborhood Hits	183	Shared Neighborhood Hits	66
SwissProt Accessions	P63098, P06705, P15117, Q08044	Gene names	PPP3R1, CNA2, CNB
Domain Architecture	No domain graphic available
Description	Calcineurin subunit B isoform 1 (Protein phosphatase 2B regulatory subunit 1) (Protein phosphatase 3 regulatory subunit B alpha isoform 1).

CANB1_MOUSE
NC score	0.227513 (rank : 23)	θ value	0.00665767 (rank : 54)
Query Neighborhood Hits	151	Target Neighborhood Hits	183	Shared Neighborhood Hits	66
SwissProt Accessions	Q63810	Gene names	Ppp3r1, Cnb
Domain Architecture
Description	Calcineurin subunit B isoform 1 (Protein phosphatase 2B regulatory subunit 1) (Protein phosphatase 3 regulatory subunit B alpha isoform 1).

NCALD_HUMAN
NC score	0.227365 (rank : 24)	θ value	0.00228821 (rank : 45)
Query Neighborhood Hits	151	Target Neighborhood Hits	153	Shared Neighborhood Hits	67
SwissProt Accessions	P61601, P29554, Q8IYC3, Q9H0W2	Gene names	NCALD
Domain Architecture
Description	Neurocalcin delta.

NCALD_MOUSE
NC score	0.227365 (rank : 25)	θ value	0.00228821 (rank : 46)
Query Neighborhood Hits	151	Target Neighborhood Hits	153	Shared Neighborhood Hits	67
SwissProt Accessions	Q91X97, Q3TJS9, Q8BZN9	Gene names	Ncald, D15Ertd412e
Domain Architecture
Description	Neurocalcin delta.

HPCL1_MOUSE
NC score	0.226997 (rank : 26)	θ value	0.00102713 (rank : 34)
Query Neighborhood Hits	151	Target Neighborhood Hits	149	Shared Neighborhood Hits	66
SwissProt Accessions	P62748, P35333	Gene names	Hpcal1
Domain Architecture	No domain graphic available
Description	Hippocalcin-like protein 1 (Visinin-like protein 3) (VILIP-3) (Neural visinin-like protein 3) (NVL-3) (NVP-3).

HPCA_HUMAN
NC score	0.225691 (rank : 27)	θ value	0.00175202 (rank : 42)
Query Neighborhood Hits	151	Target Neighborhood Hits	156	Shared Neighborhood Hits	66
SwissProt Accessions	P84074, P32076, P41211, P70510	Gene names	HPCA, BDR2
Domain Architecture	No domain graphic available
Description	Neuron-specific calcium-binding protein hippocalcin (Calcium-binding protein BDR-2).

HPCA_MOUSE
NC score	0.225691 (rank : 28)	θ value	0.00175202 (rank : 43)
Query Neighborhood Hits	151	Target Neighborhood Hits	156	Shared Neighborhood Hits	66
SwissProt Accessions	P84075, P32076, P41211, P70510	Gene names	Hpca
Domain Architecture	No domain graphic available
Description	Neuron-specific calcium-binding protein hippocalcin.

HPCL1_HUMAN
NC score	0.225375 (rank : 29)	θ value	0.00134147 (rank : 41)
Query Neighborhood Hits	151	Target Neighborhood Hits	150	Shared Neighborhood Hits	65
SwissProt Accessions	P37235, Q969S5	Gene names	HPCAL1, BDR1
Domain Architecture
Description	Hippocalcin-like protein 1 (Visinin-like protein 3) (VILIP-3) (Calcium-binding protein BDR-1) (HLP2).

GUC1B_MOUSE
NC score	0.224334 (rank : 30)	θ value	0.00869519 (rank : 56)
Query Neighborhood Hits	151	Target Neighborhood Hits	116	Shared Neighborhood Hits	63
SwissProt Accessions	Q8VBV8	Gene names	Guca1b
Domain Architecture	No domain graphic available
Description	Guanylyl cyclase-activating protein 2 (GCAP 2) (Guanylate cyclase activator 1B).

GUC1B_HUMAN
NC score	0.221713 (rank : 31)	θ value	0.0330416 (rank : 67)
Query Neighborhood Hits	151	Target Neighborhood Hits	124	Shared Neighborhood Hits	63
SwissProt Accessions	Q9UMX6, Q9NU15	Gene names	GUCA1B, GCAP2
Domain Architecture
Description	Guanylyl cyclase-activating protein 2 (GCAP 2) (Guanylate cyclase activator 1B).

GRP3_HUMAN
NC score	0.219925 (rank : 32)	θ value	1.81305 (rank : 124)
Query Neighborhood Hits	151	Target Neighborhood Hits	131	Shared Neighborhood Hits	68
SwissProt Accessions	Q8IV61, O94931	Gene names	RASGRP3, GRP3, KIAA0846
Domain Architecture
Description	RAS guanyl-releasing protein 3 (Calcium and DAG-regulated guanine nucleotide exchange factor III) (Guanine nucleotide exchange factor for Rap1).

GUC1C_HUMAN
NC score	0.217748 (rank : 33)	θ value	0.0961366 (rank : 77)
Query Neighborhood Hits	151	Target Neighborhood Hits	148	Shared Neighborhood Hits	67
SwissProt Accessions	O95843, O95844, Q9UNM0	Gene names	GUCA1C, GCAP3
Domain Architecture
Description	Guanylyl cyclase-activating protein 3 (GCAP 3) (Guanylate cyclase activator 1C).

CHP2_HUMAN
NC score	0.217128 (rank : 34)	θ value	0.00134147 (rank : 40)
Query Neighborhood Hits	151	Target Neighborhood Hits	122	Shared Neighborhood Hits	57
SwissProt Accessions	O43745	Gene names	CHP2, HCA520
Domain Architecture
Description	Calcineurin B homologous protein 2 (Hepatocellular carcinoma- associated antigen 520).

CHP1_MOUSE
NC score	0.211683 (rank : 35)	θ value	0.00869519 (rank : 55)
Query Neighborhood Hits	151	Target Neighborhood Hits	117	Shared Neighborhood Hits	59
SwissProt Accessions	P61022, Q62877, Q6ZWQ8	Gene names	Chp, Sid470
Domain Architecture
Description	Calcium-binding protein p22 (Calcium-binding protein CHP) (Calcineurin homologous protein) (Sid 470).

CHP1_HUMAN
NC score	0.209437 (rank : 36)	θ value	0.0113563 (rank : 58)
Query Neighborhood Hits	151	Target Neighborhood Hits	114	Shared Neighborhood Hits	59
SwissProt Accessions	Q99653	Gene names	CHP
Domain Architecture
Description	Calcium-binding protein p22 (Calcium-binding protein CHP) (Calcineurin homologous protein) (Calcineurin B homolog).

RASF1_MOUSE
NC score	0.207705 (rank : 37)	θ value	0.21417 (rank : 88)
Query Neighborhood Hits	151	Target Neighborhood Hits	74	Shared Neighborhood Hits	55
SwissProt Accessions	Q99MK9, Q9WUF5	Gene names	Rassf1
Domain Architecture	No domain graphic available
Description	Ras association domain-containing protein 1 (Protein 123F2).

RECO_MOUSE
NC score	0.199655 (rank : 38)	θ value	0.00390308 (rank : 50)
Query Neighborhood Hits	151	Target Neighborhood Hits	108	Shared Neighborhood Hits	61
SwissProt Accessions	P34057	Gene names	Rcvrn, Rcv1
Domain Architecture
Description	Recoverin (Cancer-associated retinopathy protein) (Protein CAR) (23 kDa photoreceptor cell-specific protein).

STAC_MOUSE
NC score	0.198547 (rank : 39)	θ value	0.0431538 (rank : 71)
Query Neighborhood Hits	151	Target Neighborhood Hits	268	Shared Neighborhood Hits	54
SwissProt Accessions	P97306	Gene names	Stac
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

KCIP1_MOUSE
NC score	0.196953 (rank : 40)	θ value	0.62314 (rank : 106)
Query Neighborhood Hits	151	Target Neighborhood Hits	113	Shared Neighborhood Hits	60
SwissProt Accessions	Q9JJ57, Q5SSA3, Q6DTJ1, Q8BGJ4, Q8C4K4, Q8CGL1, Q8K1U1, Q8K3M2	Gene names	Kcnip1, Kchip1
Domain Architecture	No domain graphic available
Description	Kv channel-interacting protein 1 (KChIP1) (A-type potassium channel modulatory protein 1) (Potassium channel-interacting protein 1).

KCIP2_HUMAN
NC score	0.196926 (rank : 41)	θ value	0.00869519 (rank : 57)
Query Neighborhood Hits	151	Target Neighborhood Hits	125	Shared Neighborhood Hits	63
SwissProt Accessions	Q9NS61, Q7Z6F1, Q96K86, Q96T41, Q96T42, Q96T43, Q96T44, Q9H0N4, Q9HD10, Q9HD11, Q9NS60, Q9NY10, Q9NZI1	Gene names	KCNIP2, KCHIP2
Domain Architecture	No domain graphic available
Description	Kv channel-interacting protein 2 (KChIP2) (A-type potassium channel modulatory protein 2) (Potassium channel-interacting protein 2) (Cardiac voltage-gated potassium channel modulatory subunit).

HPCL4_MOUSE
NC score	0.196622 (rank : 42)	θ value	θ > 10 (rank : 194)
Query Neighborhood Hits	151	Target Neighborhood Hits	123	Shared Neighborhood Hits	62
SwissProt Accessions	Q8BGZ1	Gene names	Hpcal4
Domain Architecture	No domain graphic available
Description	Hippocalcin-like protein 4 (Neural visinin-like protein 2) (NVP-2).

HPCL4_HUMAN
NC score	0.196437 (rank : 43)	θ value	θ > 10 (rank : 193)
Query Neighborhood Hits	151	Target Neighborhood Hits	123	Shared Neighborhood Hits	62
SwissProt Accessions	Q9UM19, Q5TG97, Q8N611	Gene names	HPCAL4
Domain Architecture	No domain graphic available
Description	Hippocalcin-like protein 4 (HLP4).

KCIP1_HUMAN
NC score	0.196069 (rank : 44)	θ value	0.62314 (rank : 105)
Query Neighborhood Hits	151	Target Neighborhood Hits	113	Shared Neighborhood Hits	60
SwissProt Accessions	Q9NZI2, Q5U822	Gene names	KCNIP1, KCHIP1, VABP
Domain Architecture	No domain graphic available
Description	Kv channel-interacting protein 1 (KChIP1) (A-type potassium channel modulatory protein 1) (Potassium channel-interacting protein 1) (Vesicle APC-binding protein).

KCIP2_MOUSE
NC score	0.194519 (rank : 45)	θ value	0.0193708 (rank : 61)
Query Neighborhood Hits	151	Target Neighborhood Hits	124	Shared Neighborhood Hits	63
SwissProt Accessions	Q9JJ69, Q6DTJ2, Q8K1T8, Q8K1T9, Q8K1U0, Q8VHN4, Q8VHN5, Q8VHN6, Q9JJ68	Gene names	Kcnip2, Kchip2
Domain Architecture	No domain graphic available
Description	Kv channel-interacting protein 2 (KChIP2) (A-type potassium channel modulatory protein 2) (Potassium channel-interacting protein 2).

KCIP4_MOUSE
NC score	0.192689 (rank : 46)	θ value	0.0736092 (rank : 74)
Query Neighborhood Hits	151	Target Neighborhood Hits	136	Shared Neighborhood Hits	64
SwissProt Accessions	Q6PHZ8, Q6DTJ3, Q8CAD0, Q8R4I2, Q9EQ01	Gene names	Kcnip4, Calp, Kchip4
Domain Architecture	No domain graphic available
Description	Kv channel-interacting protein 4 (KChIP4) (A-type potassium channel modulatory protein 4) (Potassium channel-interacting protein 4) (Calsenilin-like protein).

KCIP4_HUMAN
NC score	0.192559 (rank : 47)	θ value	0.0736092 (rank : 73)
Query Neighborhood Hits	151	Target Neighborhood Hits	136	Shared Neighborhood Hits	64
SwissProt Accessions	Q6PIL6, Q4W5G8, Q8NEU0, Q9BWT2, Q9H294, Q9H2A4	Gene names	KCNIP4, CALP, KCHIP4
Domain Architecture	No domain graphic available
Description	Kv channel-interacting protein 4 (KChIP4) (A-type potassium channel modulatory protein 4) (Potassium channel-interacting protein 4) (Calsenilin-like protein).

EFCB1_HUMAN
NC score	0.191739 (rank : 48)	θ value	θ > 10 (rank : 180)
Query Neighborhood Hits	151	Target Neighborhood Hits	121	Shared Neighborhood Hits	62
SwissProt Accessions	Q9HAE3	Gene names	EFCAB1
Domain Architecture	No domain graphic available
Description	EF-hand calcium-binding domain-containing protein 1.

STAC_HUMAN
NC score	0.190099 (rank : 49)	θ value	0.163984 (rank : 86)
Query Neighborhood Hits	151	Target Neighborhood Hits	276	Shared Neighborhood Hits	55
SwissProt Accessions	Q99469	Gene names	STAC
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

NCS1_HUMAN
NC score	0.188971 (rank : 50)	θ value	6.88961 (rank : 139)
Query Neighborhood Hits	151	Target Neighborhood Hits	132	Shared Neighborhood Hits	64
SwissProt Accessions	P62166, P36610, Q9UK26	Gene names	FREQ, FLUP, NCS1
Domain Architecture
Description	Neuronal calcium sensor 1 (NCS-1) (Frequenin homolog) (Frequenin-like protein) (Frequenin-like ubiquitous protein).

NCS1_MOUSE
NC score	0.188971 (rank : 51)	θ value	6.88961 (rank : 140)
Query Neighborhood Hits	151	Target Neighborhood Hits	132	Shared Neighborhood Hits	64
SwissProt Accessions	Q8BNY6	Gene names	Freq, Ncs1
Domain Architecture
Description	Neuronal calcium sensor 1 (NCS-1) (Frequenin homolog).

RECO_HUMAN
NC score	0.188655 (rank : 52)	θ value	0.00228821 (rank : 47)
Query Neighborhood Hits	151	Target Neighborhood Hits	101	Shared Neighborhood Hits	60
SwissProt Accessions	P35243	Gene names	RCVRN, RCV1
Domain Architecture
Description	Recoverin (Cancer-associated retinopathy protein) (Protein CAR).

VISL1_HUMAN
NC score	0.188193 (rank : 53)	θ value	θ > 10 (rank : 298)
Query Neighborhood Hits	151	Target Neighborhood Hits	124	Shared Neighborhood Hits	62
SwissProt Accessions	P62760, P28677, P29103, P42323, Q9UM20	Gene names	VSNL1, VISL1
Domain Architecture	No domain graphic available
Description	Visinin-like protein 1 (VILIP) (Hippocalcin-like protein 3) (HLP3).

VISL1_MOUSE
NC score	0.188193 (rank : 54)	θ value	θ > 10 (rank : 299)
Query Neighborhood Hits	151	Target Neighborhood Hits	124	Shared Neighborhood Hits	62
SwissProt Accessions	P62761, P28677, P29103, P42323, Q9UM20	Gene names	Vsnl1, Visl1
Domain Architecture	No domain graphic available
Description	Visinin-like protein 1 (VILIP) (Neural visinin-like protein 1) (NVL-1) (NVP-1).

STAC3_HUMAN
NC score	0.183893 (rank : 55)	θ value	0.0252991 (rank : 64)
Query Neighborhood Hits	151	Target Neighborhood Hits	228	Shared Neighborhood Hits	52
SwissProt Accessions	Q96MF2, Q96HU5	Gene names	STAC3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

STAC3_MOUSE
NC score	0.183843 (rank : 56)	θ value	0.0252991 (rank : 65)
Query Neighborhood Hits	151	Target Neighborhood Hits	232	Shared Neighborhood Hits	51
SwissProt Accessions	Q8BZ71	Gene names	Stac3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

CSEN_HUMAN
NC score	0.178663 (rank : 57)	θ value	θ > 10 (rank : 174)
Query Neighborhood Hits	151	Target Neighborhood Hits	128	Shared Neighborhood Hits	63
SwissProt Accessions	Q9Y2W7, Q53TJ5, Q96T40, Q9UJ84, Q9UJ85	Gene names	KCNIP3, CSEN, DREAM, KCHIP3
Domain Architecture
Description	Calsenilin (DRE-antagonist modulator) (DREAM) (Kv channel-interacting protein 3) (KChIP3) (A-type potassium channel modulatory protein 3).

CSEN_MOUSE
NC score	0.174910 (rank : 58)	θ value	θ > 10 (rank : 175)
Query Neighborhood Hits	151	Target Neighborhood Hits	117	Shared Neighborhood Hits	60
SwissProt Accessions	Q9QXT8, Q924L0, Q99PH9, Q99PI0, Q99PI2, Q99PI3, Q9JHZ5	Gene names	Kcnip3, Csen, Dream, Kchip3
Domain Architecture
Description	Calsenilin (DRE-antagonist modulator) (DREAM) (Kv channel-interacting protein 3) (A-type potassium channel modulatory protein 3) (KChIP3).

EFCB1_MOUSE
NC score	0.172737 (rank : 59)	θ value	θ > 10 (rank : 181)
Query Neighborhood Hits	151	Target Neighborhood Hits	126	Shared Neighborhood Hits	63
SwissProt Accessions	Q9D3N2, Q8BSW3, Q8C982, Q8CAI0, Q9D527, Q9D5E7	Gene names	Efcab1
Domain Architecture	No domain graphic available
Description	EF-hand calcium-binding domain-containing protein 1.

UN13B_HUMAN
NC score	0.162859 (rank : 60)	θ value	1.06291 (rank : 112)
Query Neighborhood Hits	151	Target Neighborhood Hits	217	Shared Neighborhood Hits	57
SwissProt Accessions	O14795	Gene names	UNC13B, UNC13
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

UN13A_HUMAN
NC score	0.161645 (rank : 61)	θ value	1.38821 (rank : 117)
Query Neighborhood Hits	151	Target Neighborhood Hits	285	Shared Neighborhood Hits	56
SwissProt Accessions	Q9UPW8	Gene names	UNC13A, KIAA1032
Domain Architecture	No domain graphic available
Description	Unc-13 homolog A (Munc13-1).

CHIO_MOUSE
NC score	0.158819 (rank : 62)	θ value	1.81305 (rank : 122)
Query Neighborhood Hits	151	Target Neighborhood Hits	130	Shared Neighborhood Hits	60
SwissProt Accessions	Q80XD1, Q9D9W2, Q9ER57	Gene names	Chn2, Arhgap3, Bch
Domain Architecture	No domain graphic available
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

UN13B_MOUSE
NC score	0.152758 (rank : 63)	θ value	6.88961 (rank : 144)
Query Neighborhood Hits	151	Target Neighborhood Hits	210	Shared Neighborhood Hits	55
SwissProt Accessions	Q9Z1N9	Gene names	Unc13b, Unc13a
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

CHIO_HUMAN
NC score	0.151995 (rank : 64)	θ value	1.81305 (rank : 121)
Query Neighborhood Hits	151	Target Neighborhood Hits	220	Shared Neighborhood Hits	60
SwissProt Accessions	P52757, Q75MM2	Gene names	CHN2, ARHGAP3, BCH
Domain Architecture
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

KIP2_HUMAN
NC score	0.150873 (rank : 65)	θ value	1.06291 (rank : 111)
Query Neighborhood Hits	151	Target Neighborhood Hits	107	Shared Neighborhood Hits	57
SwissProt Accessions	O75838	Gene names	CIB2, KIP2
Domain Architecture	No domain graphic available
Description	Calcium and integrin-binding protein 2 (Kinase-interacting protein 2) (KIP 2).

CHIN_HUMAN
NC score	0.150658 (rank : 66)	θ value	0.0431538 (rank : 69)
Query Neighborhood Hits	151	Target Neighborhood Hits	227	Shared Neighborhood Hits	59
SwissProt Accessions	P15882, Q53SD6, Q53SH5, Q96FB0	Gene names	CHN1, ARHGAP2, CHN
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

PDZD8_HUMAN
NC score	0.146432 (rank : 67)	θ value	θ > 10 (rank : 244)
Query Neighborhood Hits	151	Target Neighborhood Hits	185	Shared Neighborhood Hits	51
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

CHIN_MOUSE
NC score	0.145724 (rank : 68)	θ value	0.813845 (rank : 107)
Query Neighborhood Hits	151	Target Neighborhood Hits	229	Shared Neighborhood Hits	59
SwissProt Accessions	Q91V57, Q3UGY3, Q7TQE5, Q8BWU6, Q9D9B3	Gene names	Chn1, Arhgap2
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

KIP2_MOUSE
NC score	0.141950 (rank : 69)	θ value	2.36792 (rank : 128)
Query Neighborhood Hits	151	Target Neighborhood Hits	110	Shared Neighborhood Hits	59
SwissProt Accessions	Q9Z309	Gene names	Cib2, Kip2
Domain Architecture	No domain graphic available
Description	Calcium and integrin-binding protein 2 (Kinase-interacting protein 2) (KIP 2).

KIP3_HUMAN
NC score	0.136571 (rank : 70)	θ value	θ > 10 (rank : 205)
Query Neighborhood Hits	151	Target Neighborhood Hits	83	Shared Neighborhood Hits	50
SwissProt Accessions	Q96Q77	Gene names	CIB3, KIP3
Domain Architecture
Description	Calcium and integrin-binding protein 3 (Kinase-interacting protein 3) (KIP 3).

RASF1_HUMAN
NC score	0.136397 (rank : 71)	θ value	θ > 10 (rank : 255)
Query Neighborhood Hits	151	Target Neighborhood Hits	62	Shared Neighborhood Hits	48
SwissProt Accessions	Q9NS23, O14571, O60539, O60710, Q9HB04, Q9HB18, Q9NS22, Q9UND4, Q9UND5	Gene names	RASSF1, RDA32
Domain Architecture	No domain graphic available
Description	Ras association domain-containing protein 1.

KPCL_HUMAN
NC score	0.128693 (rank : 72)	θ value	3.19293e-05 (rank : 20)
Query Neighborhood Hits	151	Target Neighborhood Hits	887	Shared Neighborhood Hits	62
SwissProt Accessions	P24723, Q16246	Gene names	PRKCH, PKCL
Domain Architecture
Description	Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta) (PKC-L).

CABP7_HUMAN
NC score	0.128497 (rank : 73)	θ value	0.279714 (rank : 89)
Query Neighborhood Hits	151	Target Neighborhood Hits	205	Shared Neighborhood Hits	61
SwissProt Accessions	Q86V35	Gene names	CABP7
Domain Architecture
Description	Calcium-binding protein 7 (CaBP7).

CABP7_MOUSE
NC score	0.128497 (rank : 74)	θ value	0.279714 (rank : 90)
Query Neighborhood Hits	151	Target Neighborhood Hits	205	Shared Neighborhood Hits	61
SwissProt Accessions	Q91ZM8	Gene names	Cabp7
Domain Architecture
Description	Calcium-binding protein 7 (CaBP7).

KPCD_MOUSE
NC score	0.127643 (rank : 75)	θ value	5.44631e-05 (rank : 25)
Query Neighborhood Hits	151	Target Neighborhood Hits	888	Shared Neighborhood Hits	63
SwissProt Accessions	P28867, Q91V85, Q9Z333	Gene names	Prkcd, Pkcd
Domain Architecture
Description	Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta).

KPCD_HUMAN
NC score	0.127281 (rank : 76)	θ value	2.44474e-05 (rank : 19)
Query Neighborhood Hits	151	Target Neighborhood Hits	900	Shared Neighborhood Hits	63
SwissProt Accessions	Q05655, Q15144	Gene names	PRKCD
Domain Architecture
Description	Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta).

KPCG_HUMAN
NC score	0.127043 (rank : 77)	θ value	1.29631e-06 (rank : 17)
Query Neighborhood Hits	151	Target Neighborhood Hits	1126	Shared Neighborhood Hits	62
SwissProt Accessions	P05129	Gene names	PRKCG, PKCG
Domain Architecture
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

KPCG_MOUSE
NC score	0.126677 (rank : 78)	θ value	2.21117e-06 (rank : 18)
Query Neighborhood Hits	151	Target Neighborhood Hits	1123	Shared Neighborhood Hits	62
SwissProt Accessions	P63318, P05697	Gene names	Prkcg, Pkcc, Pkcg, Prkcc
Domain Architecture	No domain graphic available
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

KPCL_MOUSE
NC score	0.125492 (rank : 79)	θ value	0.000461057 (rank : 30)
Query Neighborhood Hits	151	Target Neighborhood Hits	891	Shared Neighborhood Hits	62
SwissProt Accessions	P23298	Gene names	Prkch, Pkch
Domain Architecture
Description	Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta) (PKC-L).

CALL3_HUMAN
NC score	0.125064 (rank : 80)	θ value	0.0736092 (rank : 72)
Query Neighborhood Hits	151	Target Neighborhood Hits	225	Shared Neighborhood Hits	64
SwissProt Accessions	P27482	Gene names	CALML3
Domain Architecture
Description	Calmodulin-like protein 3 (Calmodulin-related protein NB-1) (CaM-like protein) (CLP).

CALM_HUMAN
NC score	0.124684 (rank : 81)	θ value	0.163984 (rank : 82)
Query Neighborhood Hits	151	Target Neighborhood Hits	232	Shared Neighborhood Hits	65
SwissProt Accessions	P62158, P02593, P70667, P99014, Q13942, Q53S29, Q61379, Q61380, Q96HK3	Gene names	CALM1, CALM, CAM, CAM1
Domain Architecture
Description	Calmodulin (CaM).

CALM_MOUSE
NC score	0.124684 (rank : 82)	θ value	0.163984 (rank : 83)
Query Neighborhood Hits	151	Target Neighborhood Hits	232	Shared Neighborhood Hits	65
SwissProt Accessions	P62204, P02593, P70667, P99014, Q61379, Q61380	Gene names	Calm1, Calm, Cam, Cam1
Domain Architecture
Description	Calmodulin (CaM).

KPCE_MOUSE
NC score	0.124398 (rank : 83)	θ value	0.00390308 (rank : 49)
Query Neighborhood Hits	151	Target Neighborhood Hits	906	Shared Neighborhood Hits	59
SwissProt Accessions	P16054	Gene names	Prkce, Pkce, Pkcea
Domain Architecture
Description	Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon).

KPCE_HUMAN
NC score	0.124053 (rank : 84)	θ value	0.00390308 (rank : 48)
Query Neighborhood Hits	151	Target Neighborhood Hits	906	Shared Neighborhood Hits	59
SwissProt Accessions	Q02156, Q53SL4, Q53SM5, Q9UE81	Gene names	PRKCE, PKCE
Domain Architecture
Description	Protein kinase C epsilon type (EC 2.7.11.13) (nPKC-epsilon).

KPCT_MOUSE
NC score	0.122819 (rank : 85)	θ value	4.1701e-05 (rank : 24)
Query Neighborhood Hits	151	Target Neighborhood Hits	895	Shared Neighborhood Hits	62
SwissProt Accessions	Q02111	Gene names	Prkcq, Pkcq
Domain Architecture
Description	Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta).

KPCT_HUMAN
NC score	0.122553 (rank : 86)	θ value	4.1701e-05 (rank : 23)
Query Neighborhood Hits	151	Target Neighborhood Hits	897	Shared Neighborhood Hits	62
SwissProt Accessions	Q04759, Q3MJF1, Q64FY5, Q9H508, Q9H549	Gene names	PRKCQ, PRKCT
Domain Architecture
Description	Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta).

DUOX2_HUMAN
NC score	0.121868 (rank : 87)	θ value	0.62314 (rank : 104)
Query Neighborhood Hits	151	Target Neighborhood Hits	139	Shared Neighborhood Hits	62
SwissProt Accessions	Q9NRD8, Q9NR02, Q9UHF9	Gene names	DUOX2, LNOX2, THOX2
Domain Architecture	No domain graphic available
Description	Dual oxidase 2 precursor (EC 1.6.3.1) (EC 1.11.1.-) (NADPH oxidase/peroxidase DUOX2) (NADPH thyroid oxidase 2) (Thyroid oxidase 2) (NADH/NADPH thyroid oxidase p138-tox) (p138 thyroid oxidase) (Large NOX 2) (Long NOX 2).

EFHD1_HUMAN
NC score	0.121280 (rank : 88)	θ value	0.365318 (rank : 94)
Query Neighborhood Hits	151	Target Neighborhood Hits	108	Shared Neighborhood Hits	42
SwissProt Accessions	Q9BUP0, Q9BTF8, Q9H8I2, Q9HBQ0	Gene names	EFHD1, SWS2
Domain Architecture
Description	EF-hand domain-containing protein 1 (Swiprosin-2).

KPCB_MOUSE
NC score	0.121214 (rank : 89)	θ value	4.1701e-05 (rank : 22)
Query Neighborhood Hits	151	Target Neighborhood Hits	1117	Shared Neighborhood Hits	57
SwissProt Accessions	P68404, P04410, P04411	Gene names	Prkcb1, Pkcb, Prkcb
Domain Architecture	No domain graphic available
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

KPCB_HUMAN
NC score	0.121153 (rank : 90)	θ value	4.1701e-05 (rank : 21)
Query Neighborhood Hits	151	Target Neighborhood Hits	1121	Shared Neighborhood Hits	57
SwissProt Accessions	P05771, O43744, P05127, Q15138, Q93060, Q9UE49, Q9UE50, Q9UEH8, Q9UJ30, Q9UJ33	Gene names	PRKCB1, PKCB, PRKCB
Domain Architecture
Description	Protein kinase C beta type (EC 2.7.11.13) (PKC-beta) (PKC-B).

DUOX1_HUMAN
NC score	0.120723 (rank : 91)	θ value	0.62314 (rank : 103)
Query Neighborhood Hits	151	Target Neighborhood Hits	172	Shared Neighborhood Hits	64
SwissProt Accessions	Q9NRD9, Q6ZMB3, Q6ZR09, Q9NZC1	Gene names	DUOX1, DUOX, LNOX1, THOX1
Domain Architecture	No domain graphic available
Description	Dual oxidase 1 precursor (EC 1.6.3.1) (EC 1.11.1.-) (NADPH thyroid oxidase 1) (Thyroid oxidase 1) (Large NOX 1) (Long NOX 1).

KPCA_HUMAN
NC score	0.116374 (rank : 92)	θ value	9.29e-05 (rank : 26)
Query Neighborhood Hits	151	Target Neighborhood Hits	1070	Shared Neighborhood Hits	59
SwissProt Accessions	P17252, Q15137, Q96RE4	Gene names	PRKCA, PKCA, PRKACA
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

KPCA_MOUSE
NC score	0.116098 (rank : 93)	θ value	9.29e-05 (rank : 27)
Query Neighborhood Hits	151	Target Neighborhood Hits	1067	Shared Neighborhood Hits	59
SwissProt Accessions	P20444	Gene names	Prkca, Pkca
Domain Architecture
Description	Protein kinase C alpha type (EC 2.7.11.13) (PKC-alpha) (PKC-A).

CALB2_MOUSE
NC score	0.114038 (rank : 94)	θ value	0.279714 (rank : 92)
Query Neighborhood Hits	151	Target Neighborhood Hits	141	Shared Neighborhood Hits	52
SwissProt Accessions	Q08331, Q60964, Q9JM81	Gene names	Calb2
Domain Architecture
Description	Calretinin (CR).

AYTL1_HUMAN
NC score	0.113898 (rank : 95)	θ value	0.125558 (rank : 78)
Query Neighborhood Hits	151	Target Neighborhood Hits	140	Shared Neighborhood Hits	62
SwissProt Accessions	Q7L5N7, Q6MZJ6, Q9NX23	Gene names	AYTL1
Domain Architecture	No domain graphic available
Description	Acyltransferase-like 1 (EC 2.3.1.-).

CALB2_HUMAN
NC score	0.112932 (rank : 96)	θ value	0.279714 (rank : 91)
Query Neighborhood Hits	151	Target Neighborhood Hits	149	Shared Neighborhood Hits	52
SwissProt Accessions	P22676, Q53HD2, Q96BK4	Gene names	CALB2, CAB29
Domain Architecture
Description	Calretinin (CR) (29 kDa calbindin).

TESC_HUMAN
NC score	0.112187 (rank : 97)	θ value	θ > 10 (rank : 283)
Query Neighborhood Hits	151	Target Neighborhood Hits	64	Shared Neighborhood Hits	40
SwissProt Accessions	Q96BS2	Gene names	TESC
Domain Architecture	No domain graphic available
Description	Tescalcin (TSC).

CETN2_HUMAN
NC score	0.110342 (rank : 98)	θ value	0.0961366 (rank : 76)
Query Neighborhood Hits	151	Target Neighborhood Hits	213	Shared Neighborhood Hits	63
SwissProt Accessions	P41208, Q53XW1	Gene names	CETN2, CALT, CEN2
Domain Architecture
Description	Centrin-2 (Caltractin isoform 1).

KPCZ_MOUSE
NC score	0.110041 (rank : 99)	θ value	0.00102713 (rank : 39)
Query Neighborhood Hits	151	Target Neighborhood Hits	882	Shared Neighborhood Hits	61
SwissProt Accessions	Q02956	Gene names	Prkcz, Pkcz
Domain Architecture
Description	Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta).

TESC_MOUSE
NC score	0.109771 (rank : 100)	θ value	θ > 10 (rank : 284)
Query Neighborhood Hits	151	Target Neighborhood Hits	63	Shared Neighborhood Hits	39
SwissProt Accessions	Q9JKL5	Gene names	Tesc
Domain Architecture	No domain graphic available
Description	Tescalcin (TSC).

KPCZ_HUMAN
NC score	0.108742 (rank : 101)	θ value	0.00102713 (rank : 38)
Query Neighborhood Hits	151	Target Neighborhood Hits	884	Shared Neighborhood Hits	61
SwissProt Accessions	Q05513, Q15207, Q5SYT5, Q969S4	Gene names	PRKCZ, PKC2
Domain Architecture
Description	Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta).

NOX5_HUMAN
NC score	0.107848 (rank : 102)	θ value	8.99809 (rank : 150)
Query Neighborhood Hits	151	Target Neighborhood Hits	89	Shared Neighborhood Hits	51
SwissProt Accessions	Q96PH1, Q8TEQ1, Q8TER4, Q96PH2, Q96PJ8, Q96PJ9, Q9H6E0, Q9HAM8	Gene names	NOX5
Domain Architecture	No domain graphic available
Description	NADPH oxidase 5 (EC 1.6.3.-).

CETN2_MOUSE
NC score	0.107608 (rank : 103)	θ value	0.21417 (rank : 87)
Query Neighborhood Hits	151	Target Neighborhood Hits	211	Shared Neighborhood Hits	63
SwissProt Accessions	Q9R1K9, Q3UBB4, Q9CWM0	Gene names	Cetn2, Calt
Domain Architecture
Description	Centrin-2 (Caltractin isoform 1).

TNNC1_HUMAN
NC score	0.107099 (rank : 104)	θ value	θ > 10 (rank : 285)
Query Neighborhood Hits	151	Target Neighborhood Hits	219	Shared Neighborhood Hits	63
SwissProt Accessions	P63316, O14800, P02590, P04463	Gene names	TNNC1, TNNC
Domain Architecture	No domain graphic available
Description	Troponin C, slow skeletal and cardiac muscles (TN-C).

CALL5_HUMAN
NC score	0.106831 (rank : 105)	θ value	1.38821 (rank : 113)
Query Neighborhood Hits	151	Target Neighborhood Hits	231	Shared Neighborhood Hits	64
SwissProt Accessions	Q9NZT1, Q8IXU8	Gene names	CALML5, CLSP
Domain Architecture
Description	Calmodulin-like protein 5 (Calmodulin-like skin protein).

MRCKG_MOUSE
NC score	0.106631 (rank : 106)	θ value	2.36244e-08 (rank : 15)
Query Neighborhood Hits	151	Target Neighborhood Hits	1466	Shared Neighborhood Hits	51
SwissProt Accessions	Q80UW5	Gene names	Cdc42bpg
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42- binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma).

TNNC1_MOUSE
NC score	0.106615 (rank : 107)	θ value	θ > 10 (rank : 286)
Query Neighborhood Hits	151	Target Neighborhood Hits	221	Shared Neighborhood Hits	63
SwissProt Accessions	P19123	Gene names	Tnnc1, Tncc
Domain Architecture
Description	Troponin C, slow skeletal and cardiac muscles (TN-C).

CETN1_HUMAN
NC score	0.105828 (rank : 108)	θ value	0.62314 (rank : 102)
Query Neighborhood Hits	151	Target Neighborhood Hits	232	Shared Neighborhood Hits	63
SwissProt Accessions	Q12798	Gene names	CETN1, CEN1, CETN
Domain Architecture
Description	Centrin-1 (Caltractin isoform 2).

CETN3_MOUSE
NC score	0.104428 (rank : 109)	θ value	0.163984 (rank : 85)
Query Neighborhood Hits	151	Target Neighborhood Hits	208	Shared Neighborhood Hits	62
SwissProt Accessions	O35648	Gene names	Cetn3, Cen3
Domain Architecture
Description	Centrin-3.

MRCKG_HUMAN
NC score	0.104232 (rank : 110)	θ value	4.0297e-08 (rank : 16)
Query Neighborhood Hits	151	Target Neighborhood Hits	1519	Shared Neighborhood Hits	57
SwissProt Accessions	Q6DT37, O00565	Gene names	CDC42BPG
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42- binding protein kinase gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (Myotonic dystrophy protein kinase-like alpha) (MRCK gamma) (DMPK-like gamma).

CETN3_HUMAN
NC score	0.104183 (rank : 111)	θ value	0.163984 (rank : 84)
Query Neighborhood Hits	151	Target Neighborhood Hits	211	Shared Neighborhood Hits	62
SwissProt Accessions	O15182, Q9BS23	Gene names	CETN3, CEN3
Domain Architecture
Description	Centrin-3.

EFHD1_MOUSE
NC score	0.103464 (rank : 112)	θ value	1.81305 (rank : 123)
Query Neighborhood Hits	151	Target Neighborhood Hits	108	Shared Neighborhood Hits	44
SwissProt Accessions	Q9D4J1, Q543U4	Gene names	Efhd1, Sws2
Domain Architecture
Description	EF-hand domain-containing protein 1 (Swiprosin-2).

AYT1A_MOUSE
NC score	0.103393 (rank : 113)	θ value	0.47712 (rank : 99)
Query Neighborhood Hits	151	Target Neighborhood Hits	126	Shared Neighborhood Hits	59
SwissProt Accessions	Q8BYI6	Gene names	Aytl1a, Aytl1
Domain Architecture	No domain graphic available
Description	Acyltransferase-like 1-A (EC 2.3.1.-).

CALM4_MOUSE
NC score	0.103005 (rank : 114)	θ value	θ > 10 (rank : 170)
Query Neighborhood Hits	151	Target Neighborhood Hits	229	Shared Neighborhood Hits	59
SwissProt Accessions	Q9JM83, Q9CR31, Q9D1E9	Gene names	Calm4, Dd112
Domain Architecture
Description	Calmodulin-4 (Calcium-binding protein Dd112).

KPCI_MOUSE
NC score	0.102778 (rank : 115)	θ value	0.00102713 (rank : 37)
Query Neighborhood Hits	151	Target Neighborhood Hits	888	Shared Neighborhood Hits	61
SwissProt Accessions	Q62074	Gene names	Prkci, Pkcl
Domain Architecture
Description	Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota) (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota).

KPCI_HUMAN
NC score	0.102724 (rank : 116)	θ value	0.00102713 (rank : 36)
Query Neighborhood Hits	151	Target Neighborhood Hits	885	Shared Neighborhood Hits	59
SwissProt Accessions	P41743, Q8WW06	Gene names	PRKCI, DXS1179E
Domain Architecture
Description	Protein kinase C iota type (EC 2.7.11.13) (nPKC-iota) (Atypical protein kinase C-lambda/iota) (aPKC-lambda/iota) (PRKC-lambda/iota).

CETN1_MOUSE
NC score	0.102633 (rank : 117)	θ value	1.81305 (rank : 120)
Query Neighborhood Hits	151	Target Neighborhood Hits	231	Shared Neighborhood Hits	64
SwissProt Accessions	P41209, Q3V119, Q9D9G9, Q9DAL6	Gene names	Cetn1, Calt
Domain Architecture
Description	Centrin-1 (Caltractin).

TNNC2_MOUSE
NC score	0.102285 (rank : 118)	θ value	θ > 10 (rank : 288)
Query Neighborhood Hits	151	Target Neighborhood Hits	233	Shared Neighborhood Hits	61
SwissProt Accessions	P20801	Gene names	Tnnc2, Tncs
Domain Architecture
Description	Troponin C, skeletal muscle (STNC).

UBP32_HUMAN
NC score	0.101075 (rank : 119)	θ value	0.125558 (rank : 81)
Query Neighborhood Hits	151	Target Neighborhood Hits	170	Shared Neighborhood Hits	48
SwissProt Accessions	Q8NFA0, Q9BX85, Q9Y591	Gene names	USP32, USP10
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 32 (EC 3.1.2.15) (Ubiquitin thioesterase 32) (Ubiquitin-specific-processing protease 32) (Deubiquitinating enzyme 32) (NY-REN-60 antigen).

TNNC2_HUMAN
NC score	0.100968 (rank : 120)	θ value	θ > 10 (rank : 287)
Query Neighborhood Hits	151	Target Neighborhood Hits	234	Shared Neighborhood Hits	62
SwissProt Accessions	P02585	Gene names	TNNC2
Domain Architecture
Description	Troponin C, skeletal muscle.

CABP4_HUMAN
NC score	0.099465 (rank : 121)	θ value	1.81305 (rank : 119)
Query Neighborhood Hits	151	Target Neighborhood Hits	250	Shared Neighborhood Hits	62
SwissProt Accessions	P57796, Q8N4Z2, Q8WWY5	Gene names	CABP4
Domain Architecture
Description	Calcium-binding protein 4 (CaBP4).

AYT1B_MOUSE
NC score	0.098177 (rank : 122)	θ value	8.99809 (rank : 145)
Query Neighborhood Hits	151	Target Neighborhood Hits	113	Shared Neighborhood Hits	58
SwissProt Accessions	Q9D5U0	Gene names	Aytl1b
Domain Architecture	No domain graphic available
Description	Acyltransferase-like 1-B (EC 2.3.1.-).

CALB1_HUMAN
NC score	0.094699 (rank : 123)	θ value	8.99809 (rank : 147)
Query Neighborhood Hits	151	Target Neighborhood Hits	130	Shared Neighborhood Hits	52
SwissProt Accessions	P05937	Gene names	CALB1, CAB27
Domain Architecture
Description	Calbindin (Vitamin D-dependent calcium-binding protein, avian-type) (Calbindin D28) (D-28K).

CALB1_MOUSE
NC score	0.094029 (rank : 124)	θ value	8.99809 (rank : 148)
Query Neighborhood Hits	151	Target Neighborhood Hits	129	Shared Neighborhood Hits	52
SwissProt Accessions	P12658, Q545N6	Gene names	Calb1
Domain Architecture
Description	Calbindin (Vitamin D-dependent calcium-binding protein, avian-type) (Calbindin D28) (D-28K) (Spot 35 protein) (PCD-29).

MRCKA_HUMAN
NC score	0.093563 (rank : 125)	θ value	0.0148317 (rank : 60)
Query Neighborhood Hits	151	Target Neighborhood Hits	1999	Shared Neighborhood Hits	61
SwissProt Accessions	Q5VT25, Q59GZ1, Q5H9N9, Q5T797, Q5VT26, Q5VT27, Q86XX2, Q86XX3, Q99646	Gene names	CDC42BPA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK alpha (EC 2.7.11.1) (CDC42- binding protein kinase alpha) (Myotonic dystrophy kinase-related CDC42-binding kinase alpha) (Myotonic dystrophy protein kinase-like alpha) (MRCK alpha) (DMPK-like alpha).

CABP4_MOUSE
NC score	0.092299 (rank : 126)	θ value	θ > 10 (rank : 166)
Query Neighborhood Hits	151	Target Neighborhood Hits	212	Shared Neighborhood Hits	61
SwissProt Accessions	Q8VHC5	Gene names	Cabp4
Domain Architecture	No domain graphic available
Description	Calcium-binding protein 4 (CaBP4).

KPCD3_HUMAN
NC score	0.092219 (rank : 127)	θ value	0.0148317 (rank : 59)
Query Neighborhood Hits	151	Target Neighborhood Hits	895	Shared Neighborhood Hits	61
SwissProt Accessions	O94806	Gene names	PRKD3, EPK2, PRKCN
Domain Architecture
Description	Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) (nPKC-nu) (Protein kinase EPK2).

KPCD3_MOUSE
NC score	0.091740 (rank : 128)	θ value	0.00509761 (rank : 52)
Query Neighborhood Hits	151	Target Neighborhood Hits	901	Shared Neighborhood Hits	61
SwissProt Accessions	Q8K1Y2	Gene names	Prkd3, Prkcn
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) (nPKC-nu).

MRCKB_MOUSE
NC score	0.090451 (rank : 129)	θ value	0.00175202 (rank : 44)
Query Neighborhood Hits	151	Target Neighborhood Hits	2180	Shared Neighborhood Hits	63
SwissProt Accessions	Q7TT50, Q69ZR5, Q80W33	Gene names	Cdc42bpb, Kiaa1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

MRCKB_HUMAN
NC score	0.088241 (rank : 130)	θ value	0.0252991 (rank : 63)
Query Neighborhood Hits	151	Target Neighborhood Hits	2239	Shared Neighborhood Hits	63
SwissProt Accessions	Q9Y5S2, Q2L7A5, Q86TJ1, Q9ULU5	Gene names	CDC42BPB, KIAA1124
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (Myotonic dystrophy protein kinase-like beta) (MRCK beta) (DMPK-like beta).

KPCD1_MOUSE
NC score	0.087871 (rank : 131)	θ value	0.0330416 (rank : 68)
Query Neighborhood Hits	151	Target Neighborhood Hits	891	Shared Neighborhood Hits	61
SwissProt Accessions	Q62101	Gene names	Prkd1, Pkcm, Pkd, Prkcm
Domain Architecture
Description	Serine/threonine-protein kinase D1 (EC 2.7.11.13) (nPKC-D1) (Protein kinase D) (Protein kinase C mu type) (nPKC-mu).

KPCD2_HUMAN
NC score	0.087373 (rank : 132)	θ value	0.0252991 (rank : 62)
Query Neighborhood Hits	151	Target Neighborhood Hits	910	Shared Neighborhood Hits	62
SwissProt Accessions	Q9BZL6, Q8TB08, Q9P0T6, Q9Y3X8	Gene names	PRKD2, PKD2
Domain Architecture
Description	Serine/threonine-protein kinase D2 (EC 2.7.11.13) (nPKC-D2).

KPCD1_HUMAN
NC score	0.087154 (rank : 133)	θ value	0.0431538 (rank : 70)
Query Neighborhood Hits	151	Target Neighborhood Hits	901	Shared Neighborhood Hits	61
SwissProt Accessions	Q15139	Gene names	PRKD1, PKD, PKD1, PRKCM
Domain Architecture
Description	Serine/threonine-protein kinase D1 (EC 2.7.11.13) (nPKC-D1) (Protein kinase D) (Protein kinase C mu type) (nPKC-mu).

CABP3_HUMAN
NC score	0.085664 (rank : 134)	θ value	θ > 10 (rank : 165)
Query Neighborhood Hits	151	Target Neighborhood Hits	162	Shared Neighborhood Hits	52
SwissProt Accessions	Q9NZU6, Q9NYY0, Q9NZT9	Gene names	CABP3
Domain Architecture
Description	Calcium-binding protein 3 (CaBP3).

CALN1_HUMAN
NC score	0.082647 (rank : 135)	θ value	θ > 10 (rank : 171)
Query Neighborhood Hits	151	Target Neighborhood Hits	161	Shared Neighborhood Hits	50
SwissProt Accessions	Q9BXU9	Gene names	CALN1, CABP8
Domain Architecture
Description	Calneuron-1 (Calcium-binding protein CaBP8).

CALN1_MOUSE
NC score	0.082640 (rank : 136)	θ value	θ > 10 (rank : 172)
Query Neighborhood Hits	151	Target Neighborhood Hits	161	Shared Neighborhood Hits	50
SwissProt Accessions	Q9JJG7	Gene names	Caln1
Domain Architecture
Description	Calneuron-1.

PCAT1_HUMAN
NC score	0.082120 (rank : 137)	θ value	3.0926 (rank : 129)
Query Neighborhood Hits	151	Target Neighborhood Hits	80	Shared Neighborhood Hits	50
SwissProt Accessions	Q8NF37, Q1HAQ1, Q7Z4G6, Q8N3U7, Q8WUL8, Q9GZW6	Gene names	AYTL2, LPCAT1, PFAAP3
Domain Architecture	No domain graphic available
Description	1-acylglycerophosphocholine O-acyltransferase 1 (EC 2.3.1.23) (Lung- type acyl-coa:lysophosphatidylcholine acyltransferase 1) (Acyltransferase-like 2) (Phosphonoformate immuno-associated protein 3).

CABP2_MOUSE
NC score	0.079810 (rank : 138)	θ value	θ > 10 (rank : 164)
Query Neighborhood Hits	151	Target Neighborhood Hits	204	Shared Neighborhood Hits	56
SwissProt Accessions	Q9JLK4, Q9JLK5	Gene names	Cabp2
Domain Architecture
Description	Calcium-binding protein 2 (CaBP2).

CABP2_HUMAN
NC score	0.077899 (rank : 139)	θ value	θ > 10 (rank : 163)
Query Neighborhood Hits	151	Target Neighborhood Hits	205	Shared Neighborhood Hits	56
SwissProt Accessions	Q9NPB3	Gene names	CABP2
Domain Architecture
Description	Calcium-binding protein 2 (CaBP2).

SEGN_HUMAN
NC score	0.077882 (rank : 140)	θ value	6.88961 (rank : 142)
Query Neighborhood Hits	151	Target Neighborhood Hits	96	Shared Neighborhood Hits	42
SwissProt Accessions	O76038, Q5VV44, Q96QV7, Q9UJF6	Gene names	SCGN, SECRET
Domain Architecture
Description	Secretagogin.

CABP5_MOUSE
NC score	0.076245 (rank : 141)	θ value	θ > 10 (rank : 168)
Query Neighborhood Hits	151	Target Neighborhood Hits	207	Shared Neighborhood Hits	58
SwissProt Accessions	Q9JLK3	Gene names	Cabp5
Domain Architecture
Description	Calcium-binding protein 5 (CaBP5).

CABP5_HUMAN
NC score	0.075730 (rank : 142)	θ value	θ > 10 (rank : 167)
Query Neighborhood Hits	151	Target Neighborhood Hits	197	Shared Neighborhood Hits	54
SwissProt Accessions	Q9NP86	Gene names	CABP5
Domain Architecture
Description	Calcium-binding protein 5 (CaBP5).

CABP1_MOUSE
NC score	0.075405 (rank : 143)	θ value	θ > 10 (rank : 162)
Query Neighborhood Hits	151	Target Neighborhood Hits	197	Shared Neighborhood Hits	53
SwissProt Accessions	Q9JLK7, Q9JLK6	Gene names	Cabp1
Domain Architecture
Description	Calcium-binding protein 1 (CaBP1).

CABP1_HUMAN
NC score	0.075391 (rank : 144)	θ value	θ > 10 (rank : 161)
Query Neighborhood Hits	151	Target Neighborhood Hits	197	Shared Neighborhood Hits	53
SwissProt Accessions	Q9NZU7, O95663, Q9NZU8	Gene names	CABP1
Domain Architecture
Description	Calcium-binding protein 1 (CaBP1) (Calbrain).

CALL6_HUMAN
NC score	0.074105 (rank : 145)	θ value	θ > 10 (rank : 169)
Query Neighborhood Hits	151	Target Neighborhood Hits	157	Shared Neighborhood Hits	44
SwissProt Accessions	Q8TD86, Q6Q2C4	Gene names	CALML6, CAGLP, CALGP
Domain Architecture	No domain graphic available
Description	Calmodulin-like protein 6 (Calglandulin-like protein).

PCAT1_MOUSE
NC score	0.073985 (rank : 146)	θ value	θ > 10 (rank : 239)
Query Neighborhood Hits	151	Target Neighborhood Hits	78	Shared Neighborhood Hits	47
SwissProt Accessions	Q3TFD2, Q3TAX4, Q6NXZ6, Q8BG23, Q8BUX7, Q99JU6	Gene names	Aytl2, Lpcat1
Domain Architecture	No domain graphic available
Description	1-acylglycerophosphocholine O-acyltransferase 1 (EC 2.3.1.23) (Lung- type acyl-coa:lysophosphatidylcholine acyltransferase 1) (mLPCAT1) (Acyltransferase-like 2).

RPKL1_HUMAN
NC score	0.073615 (rank : 147)	θ value	θ > 10 (rank : 262)
Query Neighborhood Hits	151	Target Neighborhood Hits	708	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Y6S9, Q69YT9, Q6ZMQ6, Q96NR9, Q9BSU9	Gene names	RPS6KL1
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase-like 1 (EC 2.7.11.1).

RPKL1_MOUSE
NC score	0.073146 (rank : 148)	θ value	θ > 10 (rank : 263)
Query Neighborhood Hits	151	Target Neighborhood Hits	704	Shared Neighborhood Hits	32
SwissProt Accessions	Q8R2S1, Q8R1D4	Gene names	Rps6kl1
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase-like 1 (EC 2.7.11.1).

MCFD2_HUMAN
NC score	0.071570 (rank : 149)	θ value	θ > 10 (rank : 235)
Query Neighborhood Hits	151	Target Neighborhood Hits	62	Shared Neighborhood Hits	33
SwissProt Accessions	Q8NI22, Q8N3M5	Gene names	MCFD2, SDNSF
Domain Architecture
Description	Multiple coagulation factor deficiency protein 2 precursor (Neural stem cell-derived neuronal survival protein).

EFHD2_MOUSE
NC score	0.070812 (rank : 150)	θ value	θ > 10 (rank : 183)
Query Neighborhood Hits	151	Target Neighborhood Hits	88	Shared Neighborhood Hits	31
SwissProt Accessions	Q9D8Y0, Q9D0P4	Gene names	Efhd2, Sws1
Domain Architecture
Description	EF-hand domain-containing protein 2 (Swiprosin-1).

DMPK_MOUSE
NC score	0.070374 (rank : 151)	θ value	θ > 10 (rank : 179)
Query Neighborhood Hits	151	Target Neighborhood Hits	908	Shared Neighborhood Hits	32
SwissProt Accessions	P54265	Gene names	Dmpk, Dm15, Mdpk
Domain Architecture
Description	Myotonin-protein kinase (EC 2.7.11.1) (Myotonic dystrophy protein kinase) (MDPK) (DM-kinase) (DMK) (DMPK) (MT-PK).

KS6C1_MOUSE
NC score	0.070308 (rank : 152)	θ value	θ > 10 (rank : 222)
Query Neighborhood Hits	151	Target Neighborhood Hits	700	Shared Neighborhood Hits	31
SwissProt Accessions	Q8BLK9, Q3UDY3, Q6PDY4, Q8BMQ5, Q8BX49	Gene names	Rps6kc1
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase delta-1 (EC 2.7.11.1) (52 kDa ribosomal protein S6 kinase).

DMPK_HUMAN
NC score	0.070170 (rank : 153)	θ value	θ > 10 (rank : 178)
Query Neighborhood Hits	151	Target Neighborhood Hits	944	Shared Neighborhood Hits	33
SwissProt Accessions	Q09013, Q16205	Gene names	DMPK, MDPK
Domain Architecture
Description	Myotonin-protein kinase (EC 2.7.11.1) (Myotonic dystrophy protein kinase) (MDPK) (DM-kinase) (DMK) (DMPK) (MT-PK).

ONCO_MOUSE
NC score	0.069808 (rank : 154)	θ value	θ > 10 (rank : 238)
Query Neighborhood Hits	151	Target Neighborhood Hits	98	Shared Neighborhood Hits	43
SwissProt Accessions	P51879, Q62004	Gene names	Ocm
Domain Architecture
Description	Oncomodulin (OM) (Parvalbumin beta).

KS6C1_HUMAN
NC score	0.069169 (rank : 155)	θ value	θ > 10 (rank : 221)
Query Neighborhood Hits	151	Target Neighborhood Hits	682	Shared Neighborhood Hits	30
SwissProt Accessions	Q96S38, Q8TDD3, Q9NSF4, Q9UL66	Gene names	RPS6KC1, RPK118
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase delta-1 (EC 2.7.11.1) (52 kDa ribosomal protein S6 kinase) (Ribosomal S6 kinase-like protein with two PSK domains 118 kDa protein) (SPHK1-binding protein).

ONCO_HUMAN
NC score	0.068942 (rank : 156)	θ value	θ > 10 (rank : 237)
Query Neighborhood Hits	151	Target Neighborhood Hits	88	Shared Neighborhood Hits	36
SwissProt Accessions	P32930	Gene names	OCM, OCMN
Domain Architecture
Description	Oncomodulin (OM) (Parvalbumin beta).

CAYP1_HUMAN
NC score	0.068517 (rank : 157)	θ value	θ > 10 (rank : 173)
Query Neighborhood Hits	151	Target Neighborhood Hits	94	Shared Neighborhood Hits	36
SwissProt Accessions	Q13938, Q3MJA7, Q8WUZ3	Gene names	CAPS
Domain Architecture
Description	Calcyphosin (Calcyphosine).

MCFD2_MOUSE
NC score	0.068347 (rank : 158)	θ value	θ > 10 (rank : 236)
Query Neighborhood Hits	151	Target Neighborhood Hits	61	Shared Neighborhood Hits	31
SwissProt Accessions	Q8K5B2, Q3U9G5	Gene names	Mcfd2, Sdnsf
Domain Architecture
Description	Multiple coagulation factor deficiency protein 2 homolog precursor (Neural stem cell-derived neuronal survival protein).

SEGN_MOUSE
NC score	0.067830 (rank : 159)	θ value	θ > 10 (rank : 264)
Query Neighborhood Hits	151	Target Neighborhood Hits	101	Shared Neighborhood Hits	41
SwissProt Accessions	Q91WD9	Gene names	Scgn
Domain Architecture
Description	Secretagogin.

RASF5_MOUSE
NC score	0.067085 (rank : 160)	θ value	6.88961 (rank : 141)
Query Neighborhood Hits	151	Target Neighborhood Hits	72	Shared Neighborhood Hits	45
SwissProt Accessions	Q5EBH1, O70407, Q6KAR0, Q8C2E8	Gene names	Rassf5, Nore1, Rapl
Domain Architecture	No domain graphic available
Description	Ras association domain-containing family protein 5 (New ras effector 1) (Regulator for cell adhesion and polarization enriched in lymphoid tissues) (RAPL).

VAV2_HUMAN
NC score	0.066024 (rank : 161)	θ value	θ > 10 (rank : 294)
Query Neighborhood Hits	151	Target Neighborhood Hits	453	Shared Neighborhood Hits	49
SwissProt Accessions	P52735	Gene names	VAV2
Domain Architecture
Description	Protein vav-2.

PKN1_MOUSE
NC score	0.065979 (rank : 162)	θ value	θ > 10 (rank : 246)
Query Neighborhood Hits	151	Target Neighborhood Hits	888	Shared Neighborhood Hits	32
SwissProt Accessions	P70268, Q7TST2	Gene names	Pkn1, Pkn, Prk1, Prkcl1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protein kinase C- like 1) (Protein-kinase C-related kinase 1) (Protein kinase C-like PKN) (Serine-threonine protein kinase N).

PKN1_HUMAN
NC score	0.065935 (rank : 163)	θ value	θ > 10 (rank : 245)
Query Neighborhood Hits	151	Target Neighborhood Hits	886	Shared Neighborhood Hits	33
SwissProt Accessions	Q16512, Q15143, Q8IUV5	Gene names	PKN1, PKN, PRK1, PRKCL1
Domain Architecture
Description	Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protein kinase C- like 1) (Protein-kinase C-related kinase 1) (Protein kinase C-like PKN) (Serine-threonine protein kinase N) (Protein kinase PKN-alpha).

PKN3_HUMAN
NC score	0.065811 (rank : 164)	θ value	θ > 10 (rank : 249)
Query Neighborhood Hits	151	Target Neighborhood Hits	893	Shared Neighborhood Hits	33
SwissProt Accessions	Q6P5Z2, Q9UM03	Gene names	PKN3, PKNBETA
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein kinase PKN- beta) (Protein-kinase C-related kinase 3).

AKT1_HUMAN
NC score	0.065700 (rank : 165)	θ value	θ > 10 (rank : 152)
Query Neighborhood Hits	151	Target Neighborhood Hits	885	Shared Neighborhood Hits	33
SwissProt Accessions	P31749, Q9BWB6	Gene names	AKT1, PKB, RAC
Domain Architecture
Description	RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-alpha) (Protein kinase B) (PKB) (C-AKT).

LATS2_MOUSE
NC score	0.065540 (rank : 166)	θ value	θ > 10 (rank : 226)
Query Neighborhood Hits	151	Target Neighborhood Hits	879	Shared Neighborhood Hits	32
SwissProt Accessions	Q7TSJ6, Q8CDJ4, Q9JMI3	Gene names	Lats2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Large tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Kinase phosphorylated during mitosis protein).

LATS1_MOUSE
NC score	0.065469 (rank : 167)	θ value	θ > 10 (rank : 224)
Query Neighborhood Hits	151	Target Neighborhood Hits	1027	Shared Neighborhood Hits	36
SwissProt Accessions	Q8BYR2, Q9Z0W4	Gene names	Lats1, Warts
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase).

AKT1_MOUSE
NC score	0.065445 (rank : 168)	θ value	θ > 10 (rank : 153)
Query Neighborhood Hits	151	Target Neighborhood Hits	878	Shared Neighborhood Hits	33
SwissProt Accessions	P31750, Q62274	Gene names	Akt1, Akt, Rac
Domain Architecture
Description	RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-alpha) (AKT1 kinase) (Protein kinase B) (PKB) (C-AKT) (Thymoma viral proto- oncogene).

PKN2_HUMAN
NC score	0.065290 (rank : 169)	θ value	θ > 10 (rank : 247)
Query Neighborhood Hits	151	Target Neighborhood Hits	892	Shared Neighborhood Hits	32
SwissProt Accessions	Q16513, Q9H1W4	Gene names	PKN2, PRK2, PRKCL2
Domain Architecture
Description	Serine/threonine-protein kinase N2 (EC 2.7.11.13) (Protein kinase C- like 2) (Protein-kinase C-related kinase 2).

LATS1_HUMAN
NC score	0.065191 (rank : 170)	θ value	θ > 10 (rank : 223)
Query Neighborhood Hits	151	Target Neighborhood Hits	1057	Shared Neighborhood Hits	35
SwissProt Accessions	O95835, Q6PKD0	Gene names	LATS1, WARTS
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts).

PKN2_MOUSE
NC score	0.065160 (rank : 171)	θ value	θ > 10 (rank : 248)
Query Neighborhood Hits	151	Target Neighborhood Hits	899	Shared Neighborhood Hits	32
SwissProt Accessions	Q8BWW9, Q80WS2, Q8BJL7	Gene names	Pkn2, Prkcl2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N2 (EC 2.7.11.13) (Protein kinase C- like 2) (Protein-kinase C-related kinase 2).

SGK2_HUMAN
NC score	0.065125 (rank : 172)	θ value	θ > 10 (rank : 267)
Query Neighborhood Hits	151	Target Neighborhood Hits	840	Shared Neighborhood Hits	32
SwissProt Accessions	Q9HBY8, Q9UKG6	Gene names	SGK2
Domain Architecture
Description	Serine/threonine-protein kinase Sgk2 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 2).

LATS2_HUMAN
NC score	0.065022 (rank : 173)	θ value	θ > 10 (rank : 225)
Query Neighborhood Hits	151	Target Neighborhood Hits	884	Shared Neighborhood Hits	32
SwissProt Accessions	Q9NRM7, Q9P2X1	Gene names	LATS2, KPM
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Large tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Kinase phosphorylated during mitosis protein) (Warts-like kinase).

ST38L_MOUSE
NC score	0.064977 (rank : 174)	θ value	θ > 10 (rank : 278)
Query Neighborhood Hits	151	Target Neighborhood Hits	821	Shared Neighborhood Hits	33
SwissProt Accessions	Q7TSE6, Q6P6K6, Q8BWK4	Gene names	Stk38l, Ndr2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 38-like (EC 2.7.11.1) (NDR2 protein kinase) (Nuclear Dbf2-related kinase 2).

PKN3_MOUSE
NC score	0.064752 (rank : 175)	θ value	θ > 10 (rank : 250)
Query Neighborhood Hits	151	Target Neighborhood Hits	1009	Shared Neighborhood Hits	32
SwissProt Accessions	Q8K045	Gene names	Pkn3, Pknbeta
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase N3 (EC 2.7.11.13) (Protein kinase PKN- beta) (Protein-kinase C-related kinase 3).

SGK2_MOUSE
NC score	0.064547 (rank : 176)	θ value	θ > 10 (rank : 268)
Query Neighborhood Hits	151	Target Neighborhood Hits	833	Shared Neighborhood Hits	32
SwissProt Accessions	Q9QZS5, Q8R0P6	Gene names	Sgk2
Domain Architecture
Description	Serine/threonine-protein kinase Sgk2 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 2).

ST38L_HUMAN
NC score	0.064313 (rank : 177)	θ value	θ > 10 (rank : 277)
Query Neighborhood Hits	151	Target Neighborhood Hits	824	Shared Neighborhood Hits	33
SwissProt Accessions	Q9Y2H1, Q8TBX7	Gene names	STK38L, KIAA0965, NDR2
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 38-like (EC 2.7.11.1) (NDR2 protein kinase) (Nuclear Dbf2-related kinase 2).

SGK3_HUMAN
NC score	0.064226 (rank : 178)	θ value	θ > 10 (rank : 269)
Query Neighborhood Hits	151	Target Neighborhood Hits	877	Shared Neighborhood Hits	32
SwissProt Accessions	Q96BR1, Q9P1Q7, Q9UKG5	Gene names	SGK3, SGKL
Domain Architecture
Description	Serine/threonine-protein kinase Sgk3 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 3) (Serum/glucocorticoid- regulated kinase-like).

SGK1_MOUSE
NC score	0.064210 (rank : 179)	θ value	θ > 10 (rank : 266)
Query Neighborhood Hits	151	Target Neighborhood Hits	848	Shared Neighborhood Hits	32
SwissProt Accessions	Q9WVC6	Gene names	Sgk, Sgk1
Domain Architecture
Description	Serine/threonine-protein kinase Sgk1 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 1).

STK38_HUMAN
NC score	0.064104 (rank : 180)	θ value	θ > 10 (rank : 279)
Query Neighborhood Hits	151	Target Neighborhood Hits	840	Shared Neighborhood Hits	32
SwissProt Accessions	Q15208	Gene names	STK38, NDR1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 38 (EC 2.7.11.1) (NDR1 protein kinase) (Nuclear Dbf2-related kinase 1).

STK38_MOUSE
NC score	0.064064 (rank : 181)	θ value	θ > 10 (rank : 280)
Query Neighborhood Hits	151	Target Neighborhood Hits	838	Shared Neighborhood Hits	32
SwissProt Accessions	Q91VJ4	Gene names	Stk38, Ndr1
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 38 (EC 2.7.11.1) (NDR1 protein kinase) (Nuclear Dbf2-related kinase 1).

SGK1_HUMAN
NC score	0.064044 (rank : 182)	θ value	θ > 10 (rank : 265)
Query Neighborhood Hits	151	Target Neighborhood Hits	848	Shared Neighborhood Hits	32
SwissProt Accessions	O00141, Q5TCN3, Q9UN56	Gene names	SGK, SGK1
Domain Architecture
Description	Serine/threonine-protein kinase Sgk1 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 1).

SGK3_MOUSE
NC score	0.064019 (rank : 183)	θ value	θ > 10 (rank : 270)
Query Neighborhood Hits	151	Target Neighborhood Hits	882	Shared Neighborhood Hits	32
SwissProt Accessions	Q9ERE3, Q3UAY2	Gene names	Sgk3, Cisk, Sgkl
Domain Architecture
Description	Serine/threonine-protein kinase Sgk3 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 3) (Serum/glucocorticoid- regulated kinase-like) (Cytokine-independent survival kinase).

AKT2_MOUSE
NC score	0.063992 (rank : 184)	θ value	θ > 10 (rank : 155)
Query Neighborhood Hits	151	Target Neighborhood Hits	875	Shared Neighborhood Hits	33
SwissProt Accessions	Q60823	Gene names	Akt2
Domain Architecture
Description	RAC-beta serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta).

AKT2_HUMAN
NC score	0.063896 (rank : 185)	θ value	θ > 10 (rank : 154)
Query Neighborhood Hits	151	Target Neighborhood Hits	878	Shared Neighborhood Hits	33
SwissProt Accessions	P31751, Q68GC0	Gene names	AKT2
Domain Architecture
Description	RAC-beta serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-beta) (Protein kinase Akt-2) (Protein kinase B, beta) (PKB beta).

AKT3_MOUSE
NC score	0.063430 (rank : 186)	θ value	θ > 10 (rank : 157)
Query Neighborhood Hits	151	Target Neighborhood Hits	872	Shared Neighborhood Hits	32
SwissProt Accessions	Q9WUA6	Gene names	Akt3
Domain Architecture
Description	RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-gamma) (Protein kinase Akt-3) (Protein kinase B, gamma) (PKB gamma).

AKT3_HUMAN
NC score	0.063417 (rank : 187)	θ value	θ > 10 (rank : 156)
Query Neighborhood Hits	151	Target Neighborhood Hits	872	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Y243, Q96QV3, Q9UFP5	Gene names	AKT3
Domain Architecture
Description	RAC-gamma serine/threonine-protein kinase (EC 2.7.11.1) (RAC-PK-gamma) (Protein kinase Akt-3) (Protein kinase B, gamma) (PKB gamma) (STK-2).

EFHD2_HUMAN
NC score	0.063251 (rank : 188)	θ value	θ > 10 (rank : 182)
Query Neighborhood Hits	151	Target Neighborhood Hits	86	Shared Neighborhood Hits	30
SwissProt Accessions	Q96C19	Gene names	EFHD2, SWS1
Domain Architecture
Description	EF-hand domain-containing protein 2 (Swiprosin-1).

PDCD6_MOUSE
NC score	0.062995 (rank : 189)	θ value	θ > 10 (rank : 241)
Query Neighborhood Hits	151	Target Neighborhood Hits	142	Shared Neighborhood Hits	51
SwissProt Accessions	P12815, Q545I0, Q61145	Gene names	Pdcd6, Alg2
Domain Architecture
Description	Programmed cell death protein 6 (Probable calcium-binding protein ALG- 2) (PMP41) (ALG-257).

PDCD6_HUMAN
NC score	0.062669 (rank : 190)	θ value	θ > 10 (rank : 240)
Query Neighborhood Hits	151	Target Neighborhood Hits	141	Shared Neighborhood Hits	51
SwissProt Accessions	O75340	Gene names	PDCD6, ALG2
Domain Architecture
Description	Programmed cell death protein 6 (Probable calcium-binding protein ALG- 2).

VAV2_MOUSE
NC score	0.062194 (rank : 191)	θ value	θ > 10 (rank : 295)
Query Neighborhood Hits	151	Target Neighborhood Hits	456	Shared Neighborhood Hits	47
SwissProt Accessions	Q60992	Gene names	Vav2
Domain Architecture
Description	Protein vav-2.

ARBK1_HUMAN
NC score	0.062067 (rank : 192)	θ value	θ > 10 (rank : 158)
Query Neighborhood Hits	151	Target Neighborhood Hits	859	Shared Neighborhood Hits	32
SwissProt Accessions	P25098, Q13837	Gene names	ADRBK1, BARK, BARK1, GRK2
Domain Architecture
Description	Beta-adrenergic receptor kinase 1 (EC 2.7.11.15) (Beta-ARK-1) (G- protein coupled receptor kinase 2).

ARBK1_MOUSE
NC score	0.062066 (rank : 193)	θ value	θ > 10 (rank : 159)
Query Neighborhood Hits	151	Target Neighborhood Hits	849	Shared Neighborhood Hits	32
SwissProt Accessions	Q99MK8, Q99LL8	Gene names	Adrbk1, Grk2
Domain Architecture
Description	Beta-adrenergic receptor kinase 1 (EC 2.7.11.15) (Beta-ARK-1) (G- protein-coupled receptor kinase 2).

GRK4_MOUSE
NC score	0.062024 (rank : 194)	θ value	θ > 10 (rank : 187)
Query Neighborhood Hits	151	Target Neighborhood Hits	808	Shared Neighborhood Hits	30
SwissProt Accessions	O70291	Gene names	Grk4, Gprk2l
Domain Architecture
Description	G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK4).

KS6A5_MOUSE
NC score	0.061865 (rank : 195)	θ value	θ > 10 (rank : 215)
Query Neighborhood Hits	151	Target Neighborhood Hits	854	Shared Neighborhood Hits	32
SwissProt Accessions	Q8C050, Q8CI92	Gene names	Rps6ka5, Msk1
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1) (Nuclear mitogen- and stress-activated protein kinase 1) (90 kDa ribosomal protein S6 kinase 5) (RSK-like protein kinase) (RLSK).

GRK4_HUMAN
NC score	0.061853 (rank : 196)	θ value	θ > 10 (rank : 186)
Query Neighborhood Hits	151	Target Neighborhood Hits	822	Shared Neighborhood Hits	30
SwissProt Accessions	P32298, O00641, O00642, Q13293, Q13294, Q13295, Q14453, Q14725, Q15313, Q15314, Q15315, Q15316	Gene names	GRK4, GPRK2L, GPRK4
Domain Architecture
Description	G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK4) (ITI1).

ARBK2_HUMAN
NC score	0.061851 (rank : 197)	θ value	θ > 10 (rank : 160)
Query Neighborhood Hits	151	Target Neighborhood Hits	849	Shared Neighborhood Hits	32
SwissProt Accessions	P35626, Q9UGW9	Gene names	ADRBK2, BARK2, GRK3
Domain Architecture
Description	Beta-adrenergic receptor kinase 2 (EC 2.7.11.15) (Beta-ARK-2) (G- protein-coupled receptor kinase 3).

GRK7_HUMAN
NC score	0.061773 (rank : 198)	θ value	θ > 10 (rank : 192)
Query Neighborhood Hits	151	Target Neighborhood Hits	820	Shared Neighborhood Hits	32
SwissProt Accessions	Q8WTQ7	Gene names	GRK7, GPRK7
Domain Architecture
Description	G protein-coupled receptor kinase 7 precursor (EC 2.7.11.16) (G protein-coupled receptor kinase GRK7).

RK_HUMAN
NC score	0.061493 (rank : 199)	θ value	θ > 10 (rank : 256)
Query Neighborhood Hits	151	Target Neighborhood Hits	835	Shared Neighborhood Hits	32
SwissProt Accessions	Q15835	Gene names	GRK1, RHOK
Domain Architecture
Description	Rhodopsin kinase precursor (EC 2.7.11.14) (RK) (G protein-coupled receptor kinase 1).

RGNEF_MOUSE
NC score	0.061317 (rank : 200)	θ value	0.125558 (rank : 80)
Query Neighborhood Hits	151	Target Neighborhood Hits	641	Shared Neighborhood Hits	53
SwissProt Accessions	P97433	Gene names	Rgnef, Rhoip2
Domain Architecture
Description	Rho-guanine nucleotide exchange factor (Rho-interacting protein 2) (RhoGEF) (RIP2).

RASF5_HUMAN
NC score	0.061220 (rank : 201)	θ value	5.27518 (rank : 136)
Query Neighborhood Hits	151	Target Neighborhood Hits	79	Shared Neighborhood Hits	41
SwissProt Accessions	Q8WWW0, Q5SY32, Q8WWV9, Q8WXF4, Q9BT99	Gene names	RASSF5, NORE1, RAPL
Domain Architecture	No domain graphic available
Description	Ras association domain-containing family protein 5 (New ras effector 1) (Regulator for cell adhesion and polarization enriched in lymphoid tissues) (RAPL).

KS6B2_MOUSE
NC score	0.061098 (rank : 202)	θ value	θ > 10 (rank : 220)
Query Neighborhood Hits	151	Target Neighborhood Hits	871	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Z1M4	Gene names	Rps6kb2
Domain Architecture
Description	Ribosomal protein S6 kinase beta-2 (EC 2.7.11.1) (S6K-beta 2) (70 kDa ribosomal protein S6 kinase 2) (p70-S6KB) (p70 ribosomal S6 kinase beta) (p70 S6Kbeta) (S6K2).

KS6B1_HUMAN
NC score	0.060746 (rank : 203)	θ value	θ > 10 (rank : 217)
Query Neighborhood Hits	151	Target Neighborhood Hits	850	Shared Neighborhood Hits	32
SwissProt Accessions	P23443	Gene names	RPS6KB1
Domain Architecture
Description	Ribosomal protein S6 kinase beta-1 (EC 2.7.11.1) (Ribosomal protein S6 kinase I) (S6K) (S6K1) (70 kDa ribosomal protein S6 kinase 1) (p70 S6 kinase alpha) (p70(S6K)-alpha) (p70-S6K) (P70S6K) (p70-alpha).

KS6B1_MOUSE
NC score	0.060734 (rank : 204)	θ value	θ > 10 (rank : 218)
Query Neighborhood Hits	151	Target Neighborhood Hits	849	Shared Neighborhood Hits	32
SwissProt Accessions	Q8BSK8, Q8CHX0	Gene names	Rps6kb1
Domain Architecture	No domain graphic available
Description	Ribosomal protein S6 kinase beta-1 (EC 2.7.11.1) (Ribosomal protein S6 kinase I) (S6K) (S6K1) (70 kDa ribosomal protein S6 kinase 1) (p70 S6 kinase alpha) (p70(S6K)-alpha) (p70-S6K) (P70S6K).

GRK5_HUMAN
NC score	0.060730 (rank : 205)	θ value	θ > 10 (rank : 188)
Query Neighborhood Hits	151	Target Neighborhood Hits	819	Shared Neighborhood Hits	32
SwissProt Accessions	P34947	Gene names	GRK5, GPRK5
Domain Architecture
Description	G protein-coupled receptor kinase 5 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK5).

KS6B2_HUMAN
NC score	0.060675 (rank : 206)	θ value	θ > 10 (rank : 219)
Query Neighborhood Hits	151	Target Neighborhood Hits	858	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UBS0, O94809, Q9UEC1	Gene names	RPS6KB2, STK14B
Domain Architecture
Description	Ribosomal protein S6 kinase beta-2 (EC 2.7.11.1) (S6K2) (70 kDa ribosomal protein S6 kinase 2) (p70-S6KB) (p70 ribosomal S6 kinase beta) (p70 S6Kbeta) (p70 S6 kinase beta) (S6K-beta) (p70-beta) (S6 kinase-related kinase) (SRK) (Serine/threonine-protein kinase 14 beta).

KS6A4_HUMAN
NC score	0.060643 (rank : 207)	θ value	θ > 10 (rank : 212)
Query Neighborhood Hits	151	Target Neighborhood Hits	868	Shared Neighborhood Hits	32
SwissProt Accessions	O75676, O75585, Q53ES8	Gene names	RPS6KA4, MSK2
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-4 (EC 2.7.11.1) (Nuclear mitogen- and stress-activated protein kinase 2) (90 kDa ribosomal protein S6 kinase 4) (Ribosomal protein kinase B) (RSKB).

GRK5_MOUSE
NC score	0.060635 (rank : 208)	θ value	θ > 10 (rank : 189)
Query Neighborhood Hits	151	Target Neighborhood Hits	823	Shared Neighborhood Hits	32
SwissProt Accessions	Q8VEB1, O70292, O70297	Gene names	Grk5, Gprk5
Domain Architecture
Description	G protein-coupled receptor kinase 5 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK5).

KS6A4_MOUSE
NC score	0.060481 (rank : 209)	θ value	θ > 10 (rank : 213)
Query Neighborhood Hits	151	Target Neighborhood Hits	866	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Z2B9, Q91X18	Gene names	Rps6ka4, Msk2
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-4 (EC 2.7.11.1) (Nuclear mitogen- and stress-activated protein kinase 2) (90 kDa ribosomal protein S6 kinase 4) (RSK-like protein kinase) (RLSK).

GRK6_MOUSE
NC score	0.060069 (rank : 210)	θ value	θ > 10 (rank : 191)
Query Neighborhood Hits	151	Target Neighborhood Hits	820	Shared Neighborhood Hits	32
SwissProt Accessions	O70293, O70294, O70295	Gene names	Grk6, Gprk6
Domain Architecture
Description	G protein-coupled receptor kinase 6 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK6).

KAPCB_MOUSE
NC score	0.060028 (rank : 211)	θ value	θ > 10 (rank : 198)
Query Neighborhood Hits	151	Target Neighborhood Hits	836	Shared Neighborhood Hits	32
SwissProt Accessions	P68181, P05206, Q3TQH5, Q3UDD0, Q3UTH5	Gene names	Prkacb, Pkacb
Domain Architecture	No domain graphic available
Description	cAMP-dependent protein kinase, beta-catalytic subunit (EC 2.7.11.11) (PKA C-beta).

KAPCB_HUMAN
NC score	0.059955 (rank : 212)	θ value	θ > 10 (rank : 197)
Query Neighborhood Hits	151	Target Neighborhood Hits	837	Shared Neighborhood Hits	32
SwissProt Accessions	P22694, Q59GC0, Q5BNE9, Q5BNF0, Q5BNF1, Q5BNF2, Q5BNF3, Q5CZ92, Q5T1K3, Q7Z3M1, Q8IYR5, Q8IZQ0	Gene names	PRKACB
Domain Architecture
Description	cAMP-dependent protein kinase, beta-catalytic subunit (EC 2.7.11.11) (PKA C-beta).

MAST1_HUMAN
NC score	0.059904 (rank : 213)	θ value	θ > 10 (rank : 227)
Query Neighborhood Hits	151	Target Neighborhood Hits	1146	Shared Neighborhood Hits	35
SwissProt Accessions	Q9Y2H9, O00114, Q8N6X0	Gene names	MAST1, KIAA0973
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

GRK6_HUMAN
NC score	0.059784 (rank : 214)	θ value	θ > 10 (rank : 190)
Query Neighborhood Hits	151	Target Neighborhood Hits	823	Shared Neighborhood Hits	34
SwissProt Accessions	P43250, O60541, Q13652	Gene names	GRK6, GPRK6
Domain Architecture
Description	G protein-coupled receptor kinase 6 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK6).

MAST1_MOUSE
NC score	0.059745 (rank : 215)	θ value	θ > 10 (rank : 228)
Query Neighborhood Hits	151	Target Neighborhood Hits	1123	Shared Neighborhood Hits	33
SwissProt Accessions	Q9R1L5, Q7TQG9, Q80TN0	Gene names	Mast1, Kiaa0973, Sast
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 1 (EC 2.7.11.1) (Syntrophin-associated serine/threonine-protein kinase).

KAPCA_MOUSE
NC score	0.059728 (rank : 216)	θ value	θ > 10 (rank : 196)
Query Neighborhood Hits	151	Target Neighborhood Hits	836	Shared Neighborhood Hits	32
SwissProt Accessions	P05132, Q9JID0	Gene names	Prkaca, Pkaca
Domain Architecture
Description	cAMP-dependent protein kinase, alpha-catalytic subunit (EC 2.7.11.11) (PKA C-alpha).

KAPCA_HUMAN
NC score	0.059551 (rank : 217)	θ value	θ > 10 (rank : 195)
Query Neighborhood Hits	151	Target Neighborhood Hits	838	Shared Neighborhood Hits	32
SwissProt Accessions	P17612, Q9H2Y0, Q9NRB4, Q9NRH9	Gene names	PRKACA, PKACA
Domain Architecture
Description	cAMP-dependent protein kinase, alpha-catalytic subunit (EC 2.7.11.11) (PKA C-alpha).

RK_MOUSE
NC score	0.059459 (rank : 218)	θ value	θ > 10 (rank : 257)
Query Neighborhood Hits	151	Target Neighborhood Hits	829	Shared Neighborhood Hits	32
SwissProt Accessions	Q9WVL4	Gene names	Grk1, Rhok
Domain Architecture
Description	Rhodopsin kinase precursor (EC 2.7.11.14) (RK) (G protein-coupled receptor kinase 1).

PRVA_MOUSE
NC score	0.059448 (rank : 219)	θ value	θ > 10 (rank : 254)
Query Neighborhood Hits	151	Target Neighborhood Hits	77	Shared Neighborhood Hits	33
SwissProt Accessions	P32848	Gene names	Pvalb, Pva
Domain Architecture
Description	Parvalbumin alpha.

MAST3_HUMAN
NC score	0.059306 (rank : 220)	θ value	θ > 10 (rank : 231)
Query Neighborhood Hits	151	Target Neighborhood Hits	1128	Shared Neighborhood Hits	34
SwissProt Accessions	O60307, Q7LDZ8, Q9UPI0	Gene names	MAST3, KIAA0561
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 3 (EC 2.7.11.1).

KS6A5_HUMAN
NC score	0.059272 (rank : 221)	θ value	θ > 10 (rank : 214)
Query Neighborhood Hits	151	Target Neighborhood Hits	855	Shared Neighborhood Hits	32
SwissProt Accessions	O75582, O95316, Q96AF7	Gene names	RPS6KA5, MSK1
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-5 (EC 2.7.11.1) (Nuclear mitogen- and stress-activated protein kinase 1) (90 kDa ribosomal protein S6 kinase 5) (RSK-like protein kinase) (RSKL).

MAST2_HUMAN
NC score	0.058491 (rank : 222)	θ value	θ > 10 (rank : 229)
Query Neighborhood Hits	151	Target Neighborhood Hits	1189	Shared Neighborhood Hits	35
SwissProt Accessions	Q6P0Q8, O94899, Q5VT07, Q5VT08, Q7LGC4, Q8NDG1, Q96B94, Q9BYE8	Gene names	MAST2, KIAA0807, MAST205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

MAST2_MOUSE
NC score	0.058361 (rank : 223)	θ value	θ > 10 (rank : 230)
Query Neighborhood Hits	151	Target Neighborhood Hits	1110	Shared Neighborhood Hits	34
SwissProt Accessions	Q60592, Q6P9M1, Q8CHD1	Gene names	Mast2, Mast205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

MAST4_HUMAN
NC score	0.058258 (rank : 224)	θ value	θ > 10 (rank : 232)
Query Neighborhood Hits	151	Target Neighborhood Hits	1804	Shared Neighborhood Hits	39
SwissProt Accessions	O15021, Q6ZN07, Q96LY3	Gene names	MAST4, KIAA0303
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 4 (EC 2.7.11.1).

KGP1A_HUMAN
NC score	0.058164 (rank : 225)	θ value	θ > 10 (rank : 200)
Query Neighborhood Hits	151	Target Neighborhood Hits	901	Shared Neighborhood Hits	32
SwissProt Accessions	Q13976	Gene names	PRKG1, PRKGR1A
Domain Architecture
Description	cGMP-dependent protein kinase 1, alpha isozyme (EC 2.7.11.12) (CGK 1 alpha) (cGKI-alpha).

KGP1B_MOUSE
NC score	0.058127 (rank : 226)	θ value	θ > 10 (rank : 202)
Query Neighborhood Hits	151	Target Neighborhood Hits	922	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Z0Z0	Gene names	Prkg1, Prkg1b, Prkgr1b
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

ST32C_HUMAN
NC score	0.058112 (rank : 227)	θ value	θ > 10 (rank : 275)
Query Neighborhood Hits	151	Target Neighborhood Hits	832	Shared Neighborhood Hits	32
SwissProt Accessions	Q86UX6, Q5T0Q5, Q86UE1	Gene names	STK32C
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 32C (EC 2.7.11.1) (PKE) (YANK3).

KGP1B_HUMAN
NC score	0.058105 (rank : 228)	θ value	θ > 10 (rank : 201)
Query Neighborhood Hits	151	Target Neighborhood Hits	921	Shared Neighborhood Hits	32
SwissProt Accessions	P14619	Gene names	PRKG1, PRKG1B, PRKGR1B
Domain Architecture
Description	cGMP-dependent protein kinase 1, beta isozyme (EC 2.7.11.12) (cGK 1 beta) (cGKI-beta).

KAPCG_HUMAN
NC score	0.057939 (rank : 229)	θ value	θ > 10 (rank : 199)
Query Neighborhood Hits	151	Target Neighborhood Hits	845	Shared Neighborhood Hits	32
SwissProt Accessions	P22612, O60850, Q86YI1	Gene names	PRKACG
Domain Architecture
Description	cAMP-dependent protein kinase, gamma-catalytic subunit (EC 2.7.11.11) (PKA C-gamma).

PRKX_MOUSE
NC score	0.057842 (rank : 230)	θ value	θ > 10 (rank : 252)
Query Neighborhood Hits	151	Target Neighborhood Hits	846	Shared Neighborhood Hits	32
SwissProt Accessions	Q922R0, Q3UCD1, Q8BHD6, Q9QZ12	Gene names	Prkx, Pkare
Domain Architecture
Description	Serine/threonine-protein kinase PRKX (EC 2.7.11.1) (PKA-related protein kinase).

PRKX_HUMAN
NC score	0.057806 (rank : 231)	θ value	θ > 10 (rank : 251)
Query Neighborhood Hits	151	Target Neighborhood Hits	847	Shared Neighborhood Hits	32
SwissProt Accessions	P51817	Gene names	PRKX, PKX1
Domain Architecture
Description	Serine/threonine-protein kinase PRKX (EC 2.7.11.1) (Protein kinase PKX1).

ST32C_MOUSE
NC score	0.057706 (rank : 232)	θ value	θ > 10 (rank : 276)
Query Neighborhood Hits	151	Target Neighborhood Hits	824	Shared Neighborhood Hits	32
SwissProt Accessions	Q8QZV4, Q9JJG4	Gene names	Stk32c, Pkek
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 32C (EC 2.7.11.1).

MASTL_HUMAN
NC score	0.057617 (rank : 233)	θ value	θ > 10 (rank : 233)
Query Neighborhood Hits	151	Target Neighborhood Hits	894	Shared Neighborhood Hits	32
SwissProt Accessions	Q96GX5, Q5T8D5, Q5T8D7, Q8NCD6, Q96SJ5	Gene names	MASTL, THC2
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase-like (EC 2.7.11.1).

CTRO_HUMAN
NC score	0.057477 (rank : 234)	θ value	θ > 10 (rank : 176)
Query Neighborhood Hits	151	Target Neighborhood Hits	2092	Shared Neighborhood Hits	53
SwissProt Accessions	O14578, Q6XUH8, Q86UQ9, Q9UPZ7	Gene names	CIT, KIAA0949, STK21
Domain Architecture	No domain graphic available
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

MASTL_MOUSE
NC score	0.057308 (rank : 235)	θ value	θ > 10 (rank : 234)
Query Neighborhood Hits	151	Target Neighborhood Hits	862	Shared Neighborhood Hits	32
SwissProt Accessions	Q8C0P0, Q5RJW0, Q6NXX9, Q8BVF3, Q9CZH9, Q9D9V0	Gene names	Mastl
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase-like (EC 2.7.11.1).

ST32B_HUMAN
NC score	0.056993 (rank : 236)	θ value	θ > 10 (rank : 273)
Query Neighborhood Hits	151	Target Neighborhood Hits	830	Shared Neighborhood Hits	32
SwissProt Accessions	Q9NY57, Q6UXH3, Q8IY14	Gene names	STK32B
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 32B (EC 2.7.11.1) (YANK2).

ROCK2_MOUSE
NC score	0.056946 (rank : 237)	θ value	θ > 10 (rank : 261)
Query Neighborhood Hits	151	Target Neighborhood Hits	2072	Shared Neighborhood Hits	49
SwissProt Accessions	P70336, Q8BR64, Q8CBR0	Gene names	Rock2
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2).

ROCK2_HUMAN
NC score	0.056902 (rank : 238)	θ value	θ > 10 (rank : 260)
Query Neighborhood Hits	151	Target Neighborhood Hits	2073	Shared Neighborhood Hits	47
SwissProt Accessions	O75116, Q9UQN5	Gene names	ROCK2, KIAA0619
Domain Architecture
Description	Rho-associated protein kinase 2 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 2) (p164 ROCK-2) (Rho kinase 2).

VAV_HUMAN
NC score	0.056718 (rank : 239)	θ value	θ > 10 (rank : 296)
Query Neighborhood Hits	151	Target Neighborhood Hits	452	Shared Neighborhood Hits	50
SwissProt Accessions	P15498, Q15860	Gene names	VAV1, VAV
Domain Architecture
Description	Proto-oncogene vav.

ST32B_MOUSE
NC score	0.056638 (rank : 240)	θ value	θ > 10 (rank : 274)
Query Neighborhood Hits	151	Target Neighborhood Hits	828	Shared Neighborhood Hits	32
SwissProt Accessions	Q9JJX8, Q7TMD3, Q8C4E0	Gene names	Stk32b, Stk32
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 32B (EC 2.7.11.1).

ROCK1_HUMAN
NC score	0.056534 (rank : 241)	θ value	θ > 10 (rank : 258)
Query Neighborhood Hits	151	Target Neighborhood Hits	2000	Shared Neighborhood Hits	48
SwissProt Accessions	Q13464	Gene names	ROCK1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK) (NY-REN-35 antigen).

SPHK2_HUMAN
NC score	0.056232 (rank : 242)	θ value	3.0926 (rank : 132)
Query Neighborhood Hits	151	Target Neighborhood Hits	81	Shared Neighborhood Hits	10
SwissProt Accessions	Q9NRA0, Q9BRN1, Q9H0Q2, Q9NWU7	Gene names	SPHK2
Domain Architecture
Description	Sphingosine kinase 2 (EC 2.7.1.-) (SK 2) (SPK 2).

ST32A_HUMAN
NC score	0.056103 (rank : 243)	θ value	θ > 10 (rank : 271)
Query Neighborhood Hits	151	Target Neighborhood Hits	834	Shared Neighborhood Hits	32
SwissProt Accessions	Q8WU08	Gene names	STK32A
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 32A (EC 2.7.11.1) (YANK1).

KGP2_MOUSE
NC score	0.056031 (rank : 244)	θ value	θ > 10 (rank : 204)
Query Neighborhood Hits	151	Target Neighborhood Hits	1029	Shared Neighborhood Hits	32
SwissProt Accessions	Q61410	Gene names	Prkg2, Prkgr2
Domain Architecture
Description	cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).

KGP2_HUMAN
NC score	0.055843 (rank : 245)	θ value	θ > 10 (rank : 203)
Query Neighborhood Hits	151	Target Neighborhood Hits	1023	Shared Neighborhood Hits	32
SwissProt Accessions	Q13237, O00125, O60916	Gene names	PRKG2, PRKGR2
Domain Architecture
Description	cGMP-dependent protein kinase 2 (EC 2.7.11.12) (CGK 2) (cGKII) (Type II cGMP-dependent protein kinase).

KS6A6_HUMAN
NC score	0.055325 (rank : 246)	θ value	θ > 10 (rank : 216)
Query Neighborhood Hits	151	Target Neighborhood Hits	853	Shared Neighborhood Hits	32
SwissProt Accessions	Q9UK32, Q8WX28, Q9H4S6	Gene names	RPS6KA6, RSK4
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-6 (EC 2.7.11.1) (S6K-alpha 6) (90 kDa ribosomal protein S6 kinase 6) (p90-RSK 6) (Ribosomal S6 kinase 4) (RSK-4) (pp90RSK4).

F5006_HUMAN
NC score	0.055270 (rank : 247)	θ value	θ > 10 (rank : 184)
Query Neighborhood Hits	151	Target Neighborhood Hits	794	Shared Neighborhood Hits	32
SwissProt Accessions	Q96LW2, Q49A48	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized serine/threonine-protein kinase FLJ25006 (EC 2.7.11.1).

ST32A_MOUSE
NC score	0.055185 (rank : 248)	θ value	θ > 10 (rank : 272)
Query Neighborhood Hits	151	Target Neighborhood Hits	833	Shared Neighborhood Hits	32
SwissProt Accessions	Q8BGW6, Q7TPQ4	Gene names	Stk32a
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 32A (EC 2.7.11.1).

ROCK1_MOUSE
NC score	0.055177 (rank : 249)	θ value	θ > 10 (rank : 259)
Query Neighborhood Hits	151	Target Neighborhood Hits	2126	Shared Neighborhood Hits	48
SwissProt Accessions	P70335, Q8C3G4, Q8C7H0	Gene names	Rock1
Domain Architecture
Description	Rho-associated protein kinase 1 (EC 2.7.11.1) (Rho-associated, coiled- coil-containing protein kinase 1) (p160 ROCK-1) (p160ROCK).

F5006_MOUSE
NC score	0.055090 (rank : 250)	θ value	θ > 10 (rank : 185)
Query Neighborhood Hits	151	Target Neighborhood Hits	793	Shared Neighborhood Hits	32
SwissProt Accessions	Q5SYL1	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized serine/threonine-protein kinase FLJ25006 (EC 2.7.11.1).

KS6A1_MOUSE
NC score	0.055043 (rank : 251)	θ value	θ > 10 (rank : 207)
Query Neighborhood Hits	151	Target Neighborhood Hits	850	Shared Neighborhood Hits	32
SwissProt Accessions	P18653	Gene names	Rps6ka1, Rsk1
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1) (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (p90S6K) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A).

KS6A3_HUMAN
NC score	0.054840 (rank : 252)	θ value	θ > 10 (rank : 210)
Query Neighborhood Hits	151	Target Neighborhood Hits	859	Shared Neighborhood Hits	32
SwissProt Accessions	P51812, Q4VAP3, Q59H26, Q5JPK8, Q7Z3Z7	Gene names	RPS6KA3, ISPK1, RSK2
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1) (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protein kinase 1b) (MAPKAPK1B).

KS6A3_MOUSE
NC score	0.054839 (rank : 253)	θ value	θ > 10 (rank : 211)
Query Neighborhood Hits	151	Target Neighborhood Hits	860	Shared Neighborhood Hits	32
SwissProt Accessions	P18654, Q03140, Q8K3J8	Gene names	Rps6ka3, Rps6ka-rs1, Rsk2
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-3 (EC 2.7.11.1) (S6K-alpha 3) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2) (MAP kinase-activated protein kinase 1b) (MAPKAPK1B).

KS6A1_HUMAN
NC score	0.054821 (rank : 254)	θ value	θ > 10 (rank : 206)
Query Neighborhood Hits	151	Target Neighborhood Hits	854	Shared Neighborhood Hits	32
SwissProt Accessions	Q15418, Q5SVM5, Q5SVM8, Q5SVM9, Q96C05, Q9BQK2	Gene names	RPS6KA1, RSK1
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1) (S6K-alpha 1) (90 kDa ribosomal protein S6 kinase 1) (p90-RSK 1) (Ribosomal S6 kinase 1) (RSK-1) (pp90RSK1) (p90S6K) (MAP kinase-activated protein kinase 1a) (MAPKAPK1A).

KS6A2_HUMAN
NC score	0.054622 (rank : 255)	θ value	θ > 10 (rank : 208)
Query Neighborhood Hits	151	Target Neighborhood Hits	857	Shared Neighborhood Hits	32
SwissProt Accessions	Q15349, Q15419, Q59GJ3, Q5TI68, Q96J38, Q9UJN5	Gene names	RPS6KA2, RSK3
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1) (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (MAP kinase-activated protein kinase 1c) (MAPKAPK1C).

PDPK1_MOUSE
NC score	0.054575 (rank : 256)	θ value	θ > 10 (rank : 243)
Query Neighborhood Hits	151	Target Neighborhood Hits	852	Shared Neighborhood Hits	32
SwissProt Accessions	Q9Z2A0, Q9R1D8, Q9R215	Gene names	Pdpk1, Pdk1
Domain Architecture
Description	3-phosphoinositide-dependent protein kinase 1 (EC 2.7.11.1) (mPDK1).

SPHK2_MOUSE
NC score	0.054499 (rank : 257)	θ value	0.47712 (rank : 101)
Query Neighborhood Hits	151	Target Neighborhood Hits	78	Shared Neighborhood Hits	8
SwissProt Accessions	Q9JIA7, Q91VA9, Q9DBH6	Gene names	Sphk2
Domain Architecture
Description	Sphingosine kinase 2 (EC 2.7.1.-) (SK 2) (SPK 2).

RAF1_MOUSE
NC score	0.054444 (rank : 258)	θ value	3.0926 (rank : 131)
Query Neighborhood Hits	151	Target Neighborhood Hits	886	Shared Neighborhood Hits	58
SwissProt Accessions	Q99N57, Q91WH1	Gene names	Raf1, Craf
Domain Architecture
Description	RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf- 1) (C-RAF) (cRaf).

PDPK1_HUMAN
NC score	0.054433 (rank : 259)	θ value	θ > 10 (rank : 242)
Query Neighborhood Hits	151	Target Neighborhood Hits	851	Shared Neighborhood Hits	32
SwissProt Accessions	O15530	Gene names	PDPK1, PDK1
Domain Architecture
Description	3-phosphoinositide-dependent protein kinase 1 (EC 2.7.11.1) (hPDK1).

KS6A2_MOUSE
NC score	0.054429 (rank : 260)	θ value	θ > 10 (rank : 209)
Query Neighborhood Hits	151	Target Neighborhood Hits	858	Shared Neighborhood Hits	32
SwissProt Accessions	Q9WUT3, Q9D2C0	Gene names	Rps6ka2, Rsk3
Domain Architecture
Description	Ribosomal protein S6 kinase alpha-2 (EC 2.7.11.1) (S6K-alpha 2) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3) (Protein-tyrosine kinase Mpk-9) (MAP kinase- activated protein kinase 1c) (MAPKAPK1C).

CTRO_MOUSE
NC score	0.054337 (rank : 261)	θ value	θ > 10 (rank : 177)
Query Neighborhood Hits	151	Target Neighborhood Hits	2344	Shared Neighborhood Hits	52
SwissProt Accessions	P49025, O88528, O88937, O88938, Q3UM99, Q8CIJ1	Gene names	Cit
Domain Architecture
Description	Citron Rho-interacting kinase (EC 2.7.11.1) (CRIK) (Rho-interacting, serine/threonine-protein kinase 21).

PRKY_HUMAN
NC score	0.054227 (rank : 262)	θ value	θ > 10 (rank : 253)
Query Neighborhood Hits	151	Target Neighborhood Hits	844	Shared Neighborhood Hits	32
SwissProt Accessions	O43930, O15348, O15349	Gene names	PRKY
Domain Architecture
Description	Serine/threonine-protein kinase PRKY (EC 2.7.11.1).

RAF1_HUMAN
NC score	0.053861 (rank : 263)	θ value	3.0926 (rank : 130)
Query Neighborhood Hits	151	Target Neighborhood Hits	886	Shared Neighborhood Hits	58
SwissProt Accessions	P04049	Gene names	RAF1, RAF
Domain Architecture
Description	RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf- 1) (C-RAF) (cRaf).

VAV_MOUSE
NC score	0.053344 (rank : 264)	θ value	θ > 10 (rank : 297)
Query Neighborhood Hits	151	Target Neighborhood Hits	430	Shared Neighborhood Hits	48
SwissProt Accessions	P27870, Q8BTV7	Gene names	Vav1, Vav
Domain Architecture
Description	Proto-oncogene vav (p95vav).

TRIB3_HUMAN
NC score	0.052590 (rank : 265)	θ value	θ > 10 (rank : 291)
Query Neighborhood Hits	151	Target Neighborhood Hits	519	Shared Neighborhood Hits	29
SwissProt Accessions	Q96RU7, Q53GU4, Q53ZW7, Q6I9Y9, Q8TAI6, Q9H5M8, Q9NUD2	Gene names	TRIB3, C20orf97, NIPK, SKIP3, TRB3
Domain Architecture
Description	Tribbles homolog 3 (TRB-3) (Neuronal cell death-inducible putative kinase) (p65-interacting inhibitor of NF-kappaB) (SINK).

STK40_MOUSE
NC score	0.052135 (rank : 266)	θ value	θ > 10 (rank : 282)
Query Neighborhood Hits	151	Target Neighborhood Hits	751	Shared Neighborhood Hits	32
SwissProt Accessions	Q7TNL3, Q3U3G3, Q811D6, Q8BKT1, Q9D7K3	Gene names	Stk40, Lyk4
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 40 (EC 2.7.11.1) (Serine/threonine- protein kinase lyk4).

STK40_HUMAN
NC score	0.051871 (rank : 267)	θ value	θ > 10 (rank : 281)
Query Neighborhood Hits	151	Target Neighborhood Hits	751	Shared Neighborhood Hits	32
SwissProt Accessions	Q8N2I9, Q5VTK8, Q5VTK9, Q6ZMN1, Q8N2J8, Q8N3I6, Q96HN6, Q96I44, Q9BSA3, Q9H7H6	Gene names	STK40, SHIK
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase 40 (EC 2.7.11.1) (SINK-homologous serine/threonine-protein kinase).

MYO9B_HUMAN
NC score	0.051727 (rank : 268)	θ value	0.279714 (rank : 93)
Query Neighborhood Hits	151	Target Neighborhood Hits	641	Shared Neighborhood Hits	51
SwissProt Accessions	Q13459, O75314, Q9NUJ2, Q9UHN0	Gene names	MYO9B, MYR5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

TRIB3_MOUSE
NC score	0.051370 (rank : 269)	θ value	θ > 10 (rank : 292)
Query Neighborhood Hits	151	Target Neighborhood Hits	578	Shared Neighborhood Hits	30
SwissProt Accessions	Q8K4K2, Q3UMQ0, Q921E7	Gene names	Trib3, Nipk, Trb3
Domain Architecture
Description	Tribbles homolog 3 (TRB-3) (Neuronal cell death-inducible putative kinase).

TRIB1_HUMAN
NC score	0.051271 (rank : 270)	θ value	θ > 10 (rank : 289)
Query Neighborhood Hits	151	Target Neighborhood Hits	598	Shared Neighborhood Hits	32
SwissProt Accessions	Q96RU8, O15180, Q9H2Y8	Gene names	TRIB1, C8FW, GIG2, TRB1
Domain Architecture	No domain graphic available
Description	Tribbles homolog 1 (TRB-1) (SKIP1) (G-protein-coupled receptor-induced protein 2) (GIG-2).

MYO9B_MOUSE
NC score	0.050913 (rank : 271)	θ value	0.365318 (rank : 97)
Query Neighborhood Hits	151	Target Neighborhood Hits	311	Shared Neighborhood Hits	51
SwissProt Accessions	Q9QY06, Q9QY07, Q9QY08, Q9QY09	Gene names	Myo9b, Myr5
Domain Architecture
Description	Myosin-9B (Myosin IXb) (Unconventional myosin-9b).

TRIB1_MOUSE
NC score	0.050561 (rank : 272)	θ value	θ > 10 (rank : 290)
Query Neighborhood Hits	151	Target Neighborhood Hits	593	Shared Neighborhood Hits	32
SwissProt Accessions	Q8K4K4, Q8BFS7, Q8BJR9, Q8BZX3, Q91W04	Gene names	Trib1, Trb1
Domain Architecture	No domain graphic available
Description	Tribbles homolog 1 (TRB-1).

ULK4_MOUSE
NC score	0.050533 (rank : 273)	θ value	θ > 10 (rank : 293)
Query Neighborhood Hits	151	Target Neighborhood Hits	793	Shared Neighborhood Hits	32
SwissProt Accessions	Q3V129, Q2VP87, Q32LZ6, Q8BLS0, Q8C8Z5, Q9D4H6	Gene names	Ulk4
Domain Architecture	No domain graphic available
Description	Serine/threonine-protein kinase ULK4 (EC 2.7.11.1) (Unc-51-like kinase 4).

RGAP1_MOUSE
NC score	0.044632 (rank : 274)	θ value	4.03905 (rank : 135)
Query Neighborhood Hits	151	Target Neighborhood Hits	185	Shared Neighborhood Hits	38
SwissProt Accessions	Q9WVM1, Q3THR5, Q3TI41, Q3TM81	Gene names	Racgap1, Mgcracgap
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

RGAP1_HUMAN
NC score	0.042730 (rank : 275)	θ value	4.03905 (rank : 134)
Query Neighborhood Hits	151	Target Neighborhood Hits	189	Shared Neighborhood Hits	38
SwissProt Accessions	Q9H0H5, Q6PJ26, Q9NWN2, Q9P250, Q9P2W2	Gene names	RACGAP1, KIAA1478, MGCRACGAP
Domain Architecture	No domain graphic available
Description	Rac GTPase-activating protein 1 (MgcRacGAP).

KSR1_MOUSE
NC score	0.039715 (rank : 276)	θ value	4.03905 (rank : 133)
Query Neighborhood Hits	151	Target Neighborhood Hits	870	Shared Neighborhood Hits	46
SwissProt Accessions	Q61097, Q61648, Q78DX8	Gene names	Ksr1, Ksr
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-1 (Kinase suppressor of ras) (mKSR1) (Hb protein).

FSTL5_MOUSE
NC score	0.036210 (rank : 277)	θ value	0.365318 (rank : 95)
Query Neighborhood Hits	151	Target Neighborhood Hits	355	Shared Neighborhood Hits	26
SwissProt Accessions	Q8BFR2, Q80TG3, Q8C4T3	Gene names	Fstl5, Kiaa1263
Domain Architecture	No domain graphic available
Description	Follistatin-related protein 5 precursor (Follistatin-like 5) (m- D/Bsp120I 1-2).

KSR1_HUMAN
NC score	0.034409 (rank : 278)	θ value	8.99809 (rank : 149)
Query Neighborhood Hits	151	Target Neighborhood Hits	867	Shared Neighborhood Hits	45
SwissProt Accessions	Q8IVT5, Q13476	Gene names	KSR1, KSR
Domain Architecture	No domain graphic available
Description	Kinase suppressor of ras-1 (Kinase suppressor of ras).

FKBP7_HUMAN
NC score	0.028539 (rank : 279)	θ value	0.813845 (rank : 108)
Query Neighborhood Hits	151	Target Neighborhood Hits	46	Shared Neighborhood Hits	6
SwissProt Accessions	Q9Y680, Q86U65, Q96DA4, Q9Y6B0	Gene names	FKBP7, FKBP23
Domain Architecture
Description	FK506-binding protein 7 precursor (EC 5.2.1.8) (Peptidyl-prolyl cis- trans isomerase) (PPIase) (Rotamase) (FKBP-23).

MLL3_MOUSE
NC score	0.023391 (rank : 280)	θ value	1.38821 (rank : 116)
Query Neighborhood Hits	151	Target Neighborhood Hits	1399	Shared Neighborhood Hits	16
SwissProt Accessions	Q8BRH4, Q5YLV9, Q8BK12, Q8C6M3, Q923H5, Q923H6	Gene names	Mll3
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3).

FKBP7_MOUSE
NC score	0.022945 (rank : 281)	θ value	1.06291 (rank : 110)
Query Neighborhood Hits	151	Target Neighborhood Hits	58	Shared Neighborhood Hits	11
SwissProt Accessions	O54998	Gene names	Fkbp7, Fkbp23
Domain Architecture
Description	FK506-binding protein 7 precursor (EC 5.2.1.8) (Peptidyl-prolyl cis- trans isomerase) (PPIase) (Rotamase) (FKBP-23).

MLL3_HUMAN
NC score	0.020375 (rank : 282)	θ value	0.365318 (rank : 96)
Query Neighborhood Hits	151	Target Neighborhood Hits	1644	Shared Neighborhood Hits	14
SwissProt Accessions	Q8NEZ4, Q8NC02, Q8NDF6, Q9H9P4, Q9NR13, Q9P222, Q9UDR7	Gene names	MLL3, HALR, KIAA1506
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog (EC 2.1.1.43) (Histone-lysine N-methyltransferase, H3 lysine-4 specific MLL3) (Homologous to ALR protein).

LAMA2_MOUSE
NC score	0.019131 (rank : 283)	θ value	0.0736092 (rank : 75)
Query Neighborhood Hits	151	Target Neighborhood Hits	1198	Shared Neighborhood Hits	16
SwissProt Accessions	Q60675, Q05003, Q64061	Gene names	Lama2
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMB2_MOUSE
NC score	0.018801 (rank : 284)	θ value	1.38821 (rank : 115)
Query Neighborhood Hits	151	Target Neighborhood Hits	722	Shared Neighborhood Hits	15
SwissProt Accessions	Q61292, Q62182	Gene names	Lamb2, Lams
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (S-LAM).

LAMB2_HUMAN
NC score	0.017563 (rank : 285)	θ value	1.38821 (rank : 114)
Query Neighborhood Hits	151	Target Neighborhood Hits	692	Shared Neighborhood Hits	13
SwissProt Accessions	P55268, Q16321	Gene names	LAMB2, LAMS
Domain Architecture
Description	Laminin beta-2 chain precursor (S-laminin) (Laminin B1s chain).

BRAP_MOUSE
NC score	0.017184 (rank : 286)	θ value	2.36792 (rank : 127)
Query Neighborhood Hits	151	Target Neighborhood Hits	409	Shared Neighborhood Hits	8
SwissProt Accessions	Q99MP8, Q8CC00, Q8CHX1, Q99MP7, Q9CXX8	Gene names	Brap
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP).

LAMA2_HUMAN
NC score	0.016618 (rank : 287)	θ value	0.125558 (rank : 79)
Query Neighborhood Hits	151	Target Neighborhood Hits	1092	Shared Neighborhood Hits	14
SwissProt Accessions	P24043, Q14736, Q93022	Gene names	LAMA2, LAMM
Domain Architecture
Description	Laminin alpha-2 chain precursor (Laminin M chain) (Merosin heavy chain).

LAMB1_HUMAN
NC score	0.016167 (rank : 288)	θ value	1.81305 (rank : 125)
Query Neighborhood Hits	151	Target Neighborhood Hits	1018	Shared Neighborhood Hits	14
SwissProt Accessions	P07942	Gene names	LAMB1
Domain Architecture
Description	Laminin beta-1 chain precursor (Laminin B1 chain).

BRAP_HUMAN
NC score	0.015740 (rank : 289)	θ value	2.36792 (rank : 126)
Query Neighborhood Hits	151	Target Neighborhood Hits	560	Shared Neighborhood Hits	8
SwissProt Accessions	Q7Z569, O43238, O75341	Gene names	BRAP, RNF52
Domain Architecture	No domain graphic available
Description	BRCA1-associated protein (EC 6.3.2.-) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (NY-REN-63 antigen).

ITB6_MOUSE
NC score	0.014923 (rank : 290)	θ value	0.47712 (rank : 100)
Query Neighborhood Hits	151	Target Neighborhood Hits	341	Shared Neighborhood Hits	11
SwissProt Accessions	Q9Z0T9	Gene names	Itgb6
Domain Architecture
Description	Integrin beta-6 precursor.

HRX_HUMAN
NC score	0.013214 (rank : 291)	θ value	6.88961 (rank : 138)
Query Neighborhood Hits	151	Target Neighborhood Hits	825	Shared Neighborhood Hits	13
SwissProt Accessions	Q03164, Q13743, Q13744, Q14845, Q16364, Q6UBD1, Q9UMA3	Gene names	MLL, ALL1, HRX, HTRX, TRX1
Domain Architecture
Description	Zinc finger protein HRX (ALL-1) (Trithorax-like protein).

UBP4_MOUSE
NC score	0.007315 (rank : 292)	θ value	5.27518 (rank : 137)
Query Neighborhood Hits	151	Target Neighborhood Hits	90	Shared Neighborhood Hits	3
SwissProt Accessions	P35123, O54704	Gene names	Usp4, Unp
Domain Architecture
Description	Ubiquitin carboxyl-terminal hydrolase 4 (EC 3.1.2.15) (Ubiquitin thioesterase 4) (Ubiquitin-specific-processing protease 4) (Deubiquitinating enzyme 4) (Ubiquitous nuclear protein).

TRI42_MOUSE
NC score	0.007170 (rank : 293)	θ value	6.88961 (rank : 143)
Query Neighborhood Hits	151	Target Neighborhood Hits	316	Shared Neighborhood Hits	7
SwissProt Accessions	Q9D2H5	Gene names	Trim42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

TCF8_MOUSE
NC score	0.006818 (rank : 294)	θ value	0.0252991 (rank : 66)
Query Neighborhood Hits	151	Target Neighborhood Hits	1067	Shared Neighborhood Hits	7
SwissProt Accessions	Q64318, Q62519	Gene names	Tcf8, Zfhx1a, Zfx1a, Zfx1ha
Domain Architecture
Description	Transcription factor 8 (Zinc finger homeobox protein 1a) (MEB1) (Delta EF1).

BSN_MOUSE
NC score	0.006498 (rank : 295)	θ value	8.99809 (rank : 146)
Query Neighborhood Hits	151	Target Neighborhood Hits	2057	Shared Neighborhood Hits	17
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

TRI42_HUMAN
NC score	0.005441 (rank : 296)	θ value	8.99809 (rank : 151)
Query Neighborhood Hits	151	Target Neighborhood Hits	283	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IWZ5, Q8N832, Q8NDL3	Gene names	TRIM42
Domain Architecture	No domain graphic available
Description	Tripartite motif-containing protein 42.

TCF8_HUMAN
NC score	0.003717 (rank : 297)	θ value	0.365318 (rank : 98)
Query Neighborhood Hits	151	Target Neighborhood Hits	1057	Shared Neighborhood Hits	6
SwissProt Accessions	P37275, Q12924, Q13800	Gene names	TCF8, AREB6
Domain Architecture
Description	Transcription factor 8 (NIL-2-A zinc finger protein) (Negative regulator of IL2).

PRD15_HUMAN
NC score	0.000454 (rank : 298)	θ value	0.813845 (rank : 109)
Query Neighborhood Hits	151	Target Neighborhood Hits	805	Shared Neighborhood Hits	10
SwissProt Accessions	P57071, Q8N0X3, Q8NEX0, Q9NQV3	Gene names	PRDM15, C21orf83, ZNF298
Domain Architecture
Description	PR domain zinc finger protein 15 (PR domain-containing protein 15) (Zinc finger protein 298).

ZN335_HUMAN
NC score	-0.000961 (rank : 299)	θ value	1.38821 (rank : 118)
Query Neighborhood Hits	151	Target Neighborhood Hits	973	Shared Neighborhood Hits	8
SwissProt Accessions	Q9H4Z2, Q9H684	Gene names	ZNF335
Domain Architecture	No domain graphic available
Description	Zinc finger protein 335.