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Network neighborhood for query Sequence : DGKE_MOUSE

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DGKE_MOUSE
SwissProt Accessions	Q9R1C6	Gene names	Dgke
Domain Architecture
Description	Diacylglycerol kinase epsilon (EC 2.7.1.107) (Diglyceride kinase epsilon) (DGK-epsilon) (DAG kinase epsilon).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

DGKE_HUMAN
θ value	0 (rank : 1)	NC score	0.995351 (rank : 2)
Query Neighborhood Hits	30	Target Neighborhood Hits	32	Shared Neighborhood Hits	25
SwissProt Accessions	P52429, Q9UKQ3	Gene names	DGKE, DAGK5
Domain Architecture
Description	Diacylglycerol kinase epsilon (EC 2.7.1.107) (Diglyceride kinase epsilon) (DGK-epsilon) (DAG kinase epsilon).

DGKE_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	30	Target Neighborhood Hits	30	Shared Neighborhood Hits	30
SwissProt Accessions	Q9R1C6	Gene names	Dgke
Domain Architecture
Description	Diacylglycerol kinase epsilon (EC 2.7.1.107) (Diglyceride kinase epsilon) (DGK-epsilon) (DAG kinase epsilon).

DGKB_HUMAN
θ value	5.8972e-76 (rank : 3)	NC score	0.836264 (rank : 8)
Query Neighborhood Hits	30	Target Neighborhood Hits	238	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y6T7, O75241, Q75MF9, Q75MU7, Q86UI5, Q86UM9, Q9UQ29	Gene names	DGKB, DAGK2, KIAA0718
Domain Architecture
Description	Diacylglycerol kinase beta (EC 2.7.1.107) (Diglyceride kinase beta) (DGK-beta) (DAG kinase beta) (90 kDa diacylglycerol kinase).

DGKG_HUMAN
θ value	3.82246e-75 (rank : 4)	NC score	0.872355 (rank : 5)
Query Neighborhood Hits	30	Target Neighborhood Hits	171	Shared Neighborhood Hits	24
SwissProt Accessions	P49619	Gene names	DGKG, DAGK3
Domain Architecture
Description	Diacylglycerol kinase gamma (EC 2.7.1.107) (Diglyceride kinase gamma) (DGK-gamma) (DAG kinase gamma).

DGKG_MOUSE
θ value	2.73936e-73 (rank : 5)	NC score	0.864318 (rank : 6)
Query Neighborhood Hits	30	Target Neighborhood Hits	188	Shared Neighborhood Hits	24
SwissProt Accessions	Q91WG7	Gene names	Dgkg, Dagk3
Domain Architecture
Description	Diacylglycerol kinase gamma (EC 2.7.1.107) (Diglyceride kinase gamma) (DGK-gamma) (DAG kinase gamma) (88 kDa diacylglycerol kinase).

DGKA_HUMAN
θ value	6.10265e-73 (rank : 6)	NC score	0.892328 (rank : 3)
Query Neighborhood Hits	30	Target Neighborhood Hits	151	Shared Neighborhood Hits	24
SwissProt Accessions	P23743, O75481, O75482, O75483	Gene names	DGKA, DAGK, DAGK1
Domain Architecture
Description	Diacylglycerol kinase alpha (EC 2.7.1.107) (Diglyceride kinase alpha) (DGK-alpha) (DAG kinase alpha) (80 kDa diacylglycerol kinase).

DGKA_MOUSE
θ value	4.37348e-71 (rank : 7)	NC score	0.887117 (rank : 4)
Query Neighborhood Hits	30	Target Neighborhood Hits	146	Shared Neighborhood Hits	22
SwissProt Accessions	O88673, Q922X2	Gene names	Dgka, Dagk1
Domain Architecture
Description	Diacylglycerol kinase alpha (EC 2.7.1.107) (Diglyceride kinase alpha) (DGK-alpha) (DAG kinase alpha) (80 kDa diacylglycerol kinase).

DGKQ_HUMAN
θ value	8.53533e-67 (rank : 8)	NC score	0.860582 (rank : 7)
Query Neighborhood Hits	30	Target Neighborhood Hits	131	Shared Neighborhood Hits	24
SwissProt Accessions	P52824	Gene names	DGKQ, DAGK4
Domain Architecture
Description	Diacylglycerol kinase theta (EC 2.7.1.107) (Diglyceride kinase theta) (DGK-theta) (DAG kinase theta).

DGKI_HUMAN
θ value	4.10295e-61 (rank : 9)	NC score	0.768362 (rank : 13)
Query Neighborhood Hits	30	Target Neighborhood Hits	609	Shared Neighborhood Hits	14
SwissProt Accessions	O75912, Q9NZ49	Gene names	DGKI
Domain Architecture
Description	Diacylglycerol kinase iota (EC 2.7.1.107) (Diglyceride kinase iota) (DGK-iota) (DAG kinase iota).

DGKZ_MOUSE
θ value	1.7238e-59 (rank : 10)	NC score	0.781439 (rank : 9)
Query Neighborhood Hits	30	Target Neighborhood Hits	542	Shared Neighborhood Hits	14
SwissProt Accessions	Q80UP3	Gene names	Dgkz
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

DGKZ_HUMAN
θ value	1.90589e-58 (rank : 11)	NC score	0.776319 (rank : 11)
Query Neighborhood Hits	30	Target Neighborhood Hits	551	Shared Neighborhood Hits	14
SwissProt Accessions	Q13574, O00542	Gene names	DGKZ, DAGK6
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

DGKH_HUMAN
θ value	2.58187e-47 (rank : 12)	NC score	0.774397 (rank : 12)
Query Neighborhood Hits	30	Target Neighborhood Hits	255	Shared Neighborhood Hits	24
SwissProt Accessions	Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9	Gene names	DGKH
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).

DGKD_HUMAN
θ value	1.28137e-46 (rank : 13)	NC score	0.778894 (rank : 10)
Query Neighborhood Hits	30	Target Neighborhood Hits	231	Shared Neighborhood Hits	24
SwissProt Accessions	Q16760, Q14158, Q6PK55, Q8NG53	Gene names	DGKD, KIAA0145
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase delta (EC 2.7.1.107) (Diglyceride kinase delta) (DGK-delta) (DAG kinase delta) (130 kDa diacylglycerol kinase).

DGKK_HUMAN
θ value	1.67352e-46 (rank : 14)	NC score	0.766601 (rank : 14)
Query Neighborhood Hits	30	Target Neighborhood Hits	378	Shared Neighborhood Hits	20
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

KPCT_HUMAN
θ value	0.0563607 (rank : 15)	NC score	0.052130 (rank : 53)
Query Neighborhood Hits	30	Target Neighborhood Hits	897	Shared Neighborhood Hits	21
SwissProt Accessions	Q04759, Q3MJF1, Q64FY5, Q9H508, Q9H549	Gene names	PRKCQ, PRKCT
Domain Architecture
Description	Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta).

KPCT_MOUSE
θ value	0.0563607 (rank : 16)	NC score	0.052354 (rank : 52)
Query Neighborhood Hits	30	Target Neighborhood Hits	895	Shared Neighborhood Hits	21
SwissProt Accessions	Q02111	Gene names	Prkcq, Pkcq
Domain Architecture
Description	Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta).

KPCD_MOUSE
θ value	0.125558 (rank : 17)	NC score	0.054454 (rank : 46)
Query Neighborhood Hits	30	Target Neighborhood Hits	888	Shared Neighborhood Hits	21
SwissProt Accessions	P28867, Q91V85, Q9Z333	Gene names	Prkcd, Pkcd
Domain Architecture
Description	Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta).

KPCD_HUMAN
θ value	0.163984 (rank : 18)	NC score	0.054099 (rank : 47)
Query Neighborhood Hits	30	Target Neighborhood Hits	900	Shared Neighborhood Hits	21
SwissProt Accessions	Q05655, Q15144	Gene names	PRKCD
Domain Architecture
Description	Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta).

BRD1_HUMAN
θ value	1.38821 (rank : 19)	NC score	0.015650 (rank : 62)
Query Neighborhood Hits	30	Target Neighborhood Hits	188	Shared Neighborhood Hits	5
SwissProt Accessions	O95696	Gene names	BRD1, BRL, BRPF2
Domain Architecture
Description	Bromodomain-containing protein 1 (BR140-like protein).

PHF14_HUMAN
θ value	1.81305 (rank : 20)	NC score	0.022146 (rank : 59)
Query Neighborhood Hits	30	Target Neighborhood Hits	447	Shared Neighborhood Hits	6
SwissProt Accessions	O94880	Gene names	PHF14, KIAA0783
Domain Architecture	No domain graphic available
Description	PHD finger protein 14.

PHF14_MOUSE
θ value	1.81305 (rank : 21)	NC score	0.022846 (rank : 58)
Query Neighborhood Hits	30	Target Neighborhood Hits	342	Shared Neighborhood Hits	6
SwissProt Accessions	Q9D4H9, Q810Z6, Q8C284, Q8CGF8, Q9D1Q8	Gene names	Phf14
Domain Architecture
Description	PHD finger protein 14.

KPCG_HUMAN
θ value	2.36792 (rank : 22)	NC score	0.048455 (rank : 56)
Query Neighborhood Hits	30	Target Neighborhood Hits	1126	Shared Neighborhood Hits	21
SwissProt Accessions	P05129	Gene names	PRKCG, PKCG
Domain Architecture
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

KPCG_MOUSE
θ value	2.36792 (rank : 23)	NC score	0.048098 (rank : 57)
Query Neighborhood Hits	30	Target Neighborhood Hits	1123	Shared Neighborhood Hits	21
SwissProt Accessions	P63318, P05697	Gene names	Prkcg, Pkcc, Pkcg, Prkcc
Domain Architecture	No domain graphic available
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

ZNFX1_MOUSE
θ value	2.36792 (rank : 24)	NC score	0.015197 (rank : 64)
Query Neighborhood Hits	30	Target Neighborhood Hits	407	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

ZNFX1_HUMAN
θ value	4.03905 (rank : 25)	NC score	0.014489 (rank : 65)
Query Neighborhood Hits	30	Target Neighborhood Hits	308	Shared Neighborhood Hits	3
SwissProt Accessions	Q9P2E3, Q9BQM7, Q9BQM8, Q9H8C1, Q9H9S2, Q9NUM1, Q9NWW1	Gene names	ZNFX1, KIAA1404
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

CHIO_HUMAN
θ value	5.27518 (rank : 26)	NC score	0.063876 (rank : 28)
Query Neighborhood Hits	30	Target Neighborhood Hits	220	Shared Neighborhood Hits	18
SwissProt Accessions	P52757, Q75MM2	Gene names	CHN2, ARHGAP3, BCH
Domain Architecture
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

CHIO_MOUSE
θ value	5.27518 (rank : 27)	NC score	0.067522 (rank : 23)
Query Neighborhood Hits	30	Target Neighborhood Hits	130	Shared Neighborhood Hits	18
SwissProt Accessions	Q80XD1, Q9D9W2, Q9ER57	Gene names	Chn2, Arhgap3, Bch
Domain Architecture	No domain graphic available
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

RAF1_HUMAN
θ value	5.27518 (rank : 28)	NC score	0.019916 (rank : 61)
Query Neighborhood Hits	30	Target Neighborhood Hits	886	Shared Neighborhood Hits	20
SwissProt Accessions	P04049	Gene names	RAF1, RAF
Domain Architecture
Description	RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf- 1) (C-RAF) (cRaf).

RAF1_MOUSE
θ value	5.27518 (rank : 29)	NC score	0.019995 (rank : 60)
Query Neighborhood Hits	30	Target Neighborhood Hits	886	Shared Neighborhood Hits	20
SwissProt Accessions	Q99N57, Q91WH1	Gene names	Raf1, Craf
Domain Architecture
Description	RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf- 1) (C-RAF) (cRaf).

BRPF3_HUMAN
θ value	8.99809 (rank : 30)	NC score	0.015613 (rank : 63)
Query Neighborhood Hits	30	Target Neighborhood Hits	217	Shared Neighborhood Hits	6
SwissProt Accessions	Q9ULD4, Q5R3K8	Gene names	BRPF3, KIAA1286
Domain Architecture	No domain graphic available
Description	Bromodomain and PHD finger-containing protein 3.

CANB1_HUMAN
θ value	θ > 10 (rank : 31)	NC score	0.055117 (rank : 45)
Query Neighborhood Hits	30	Target Neighborhood Hits	183	Shared Neighborhood Hits	5
SwissProt Accessions	P63098, P06705, P15117, Q08044	Gene names	PPP3R1, CNA2, CNB
Domain Architecture	No domain graphic available
Description	Calcineurin subunit B isoform 1 (Protein phosphatase 2B regulatory subunit 1) (Protein phosphatase 3 regulatory subunit B alpha isoform 1).

CANB1_MOUSE
θ value	θ > 10 (rank : 32)	NC score	0.055122 (rank : 44)
Query Neighborhood Hits	30	Target Neighborhood Hits	183	Shared Neighborhood Hits	5
SwissProt Accessions	Q63810	Gene names	Ppp3r1, Cnb
Domain Architecture
Description	Calcineurin subunit B isoform 1 (Protein phosphatase 2B regulatory subunit 1) (Protein phosphatase 3 regulatory subunit B alpha isoform 1).

CANB2_HUMAN
θ value	θ > 10 (rank : 33)	NC score	0.053471 (rank : 48)
Query Neighborhood Hits	30	Target Neighborhood Hits	163	Shared Neighborhood Hits	5
SwissProt Accessions	Q96LZ3, Q7Z4V8, Q8WYJ4	Gene names	PPP3R2, CBLP
Domain Architecture	No domain graphic available
Description	Calcineurin subunit B isoform 2 (Protein phosphatase 2B regulatory subunit 2) (Protein phosphatase 3 regulatory subunit B beta isoform) (Calcineurin B-like protein) (CBLP) (CNBII).

CANB2_MOUSE
θ value	θ > 10 (rank : 34)	NC score	0.059083 (rank : 37)
Query Neighborhood Hits	30	Target Neighborhood Hits	173	Shared Neighborhood Hits	5
SwissProt Accessions	Q63811	Gene names	Ppp3r2
Domain Architecture
Description	Calcineurin subunit B isoform 2 (Protein phosphatase 2B regulatory subunit 2) (Protein phosphatase 3 regulatory subunit B beta isoform).

CHIN_HUMAN
θ value	θ > 10 (rank : 35)	NC score	0.059731 (rank : 36)
Query Neighborhood Hits	30	Target Neighborhood Hits	227	Shared Neighborhood Hits	17
SwissProt Accessions	P15882, Q53SD6, Q53SH5, Q96FB0	Gene names	CHN1, ARHGAP2, CHN
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

CHIN_MOUSE
θ value	θ > 10 (rank : 36)	NC score	0.055802 (rank : 43)
Query Neighborhood Hits	30	Target Neighborhood Hits	229	Shared Neighborhood Hits	17
SwissProt Accessions	Q91V57, Q3UGY3, Q7TQE5, Q8BWU6, Q9D9B3	Gene names	Chn1, Arhgap2
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

CHP2_HUMAN
θ value	θ > 10 (rank : 37)	NC score	0.058511 (rank : 41)
Query Neighborhood Hits	30	Target Neighborhood Hits	122	Shared Neighborhood Hits	5
SwissProt Accessions	O43745	Gene names	CHP2, HCA520
Domain Architecture
Description	Calcineurin B homologous protein 2 (Hepatocellular carcinoma- associated antigen 520).

CHP2_MOUSE
θ value	θ > 10 (rank : 38)	NC score	0.066063 (rank : 24)
Query Neighborhood Hits	30	Target Neighborhood Hits	122	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D869	Gene names	Chp2, Hca520
Domain Architecture
Description	Calcineurin B homologous protein 2 (Hepatocellular carcinoma- associated antigen 520 homolog).

EFHD1_HUMAN
θ value	θ > 10 (rank : 39)	NC score	0.052407 (rank : 51)
Query Neighborhood Hits	30	Target Neighborhood Hits	108	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BUP0, Q9BTF8, Q9H8I2, Q9HBQ0	Gene names	EFHD1, SWS2
Domain Architecture
Description	EF-hand domain-containing protein 1 (Swiprosin-2).

GRP3_HUMAN
θ value	θ > 10 (rank : 40)	NC score	0.100414 (rank : 16)
Query Neighborhood Hits	30	Target Neighborhood Hits	131	Shared Neighborhood Hits	17
SwissProt Accessions	Q8IV61, O94931	Gene names	RASGRP3, GRP3, KIAA0846
Domain Architecture
Description	RAS guanyl-releasing protein 3 (Calcium and DAG-regulated guanine nucleotide exchange factor III) (Guanine nucleotide exchange factor for Rap1).

GUC1A_HUMAN
θ value	θ > 10 (rank : 41)	NC score	0.064006 (rank : 27)
Query Neighborhood Hits	30	Target Neighborhood Hits	147	Shared Neighborhood Hits	5
SwissProt Accessions	P43080, Q9NU14	Gene names	GUCA1A, GCAP, GCAP1, GUCA1
Domain Architecture
Description	Guanylyl cyclase-activating protein 1 (GCAP 1) (Guanylate cyclase activator 1A).

GUC1A_MOUSE
θ value	θ > 10 (rank : 42)	NC score	0.064690 (rank : 26)
Query Neighborhood Hits	30	Target Neighborhood Hits	152	Shared Neighborhood Hits	5
SwissProt Accessions	P43081	Gene names	Guca1a, Gcap, Gcap1, Guca1
Domain Architecture
Description	Guanylyl cyclase-activating protein 1 (GCAP 1) (Guanylate cyclase activator 1A).

GUC1B_HUMAN
θ value	θ > 10 (rank : 43)	NC score	0.057400 (rank : 42)
Query Neighborhood Hits	30	Target Neighborhood Hits	124	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UMX6, Q9NU15	Gene names	GUCA1B, GCAP2
Domain Architecture
Description	Guanylyl cyclase-activating protein 2 (GCAP 2) (Guanylate cyclase activator 1B).

GUC1B_MOUSE
θ value	θ > 10 (rank : 44)	NC score	0.058737 (rank : 38)
Query Neighborhood Hits	30	Target Neighborhood Hits	116	Shared Neighborhood Hits	5
SwissProt Accessions	Q8VBV8	Gene names	Guca1b
Domain Architecture	No domain graphic available
Description	Guanylyl cyclase-activating protein 2 (GCAP 2) (Guanylate cyclase activator 1B).

GUC1C_HUMAN
θ value	θ > 10 (rank : 45)	NC score	0.053075 (rank : 50)
Query Neighborhood Hits	30	Target Neighborhood Hits	148	Shared Neighborhood Hits	5
SwissProt Accessions	O95843, O95844, Q9UNM0	Gene names	GUCA1C, GCAP3
Domain Architecture
Description	Guanylyl cyclase-activating protein 3 (GCAP 3) (Guanylate cyclase activator 1C).

HPCA_HUMAN
θ value	θ > 10 (rank : 46)	NC score	0.060035 (rank : 34)
Query Neighborhood Hits	30	Target Neighborhood Hits	156	Shared Neighborhood Hits	5
SwissProt Accessions	P84074, P32076, P41211, P70510	Gene names	HPCA, BDR2
Domain Architecture	No domain graphic available
Description	Neuron-specific calcium-binding protein hippocalcin (Calcium-binding protein BDR-2).

HPCA_MOUSE
θ value	θ > 10 (rank : 47)	NC score	0.060035 (rank : 35)
Query Neighborhood Hits	30	Target Neighborhood Hits	156	Shared Neighborhood Hits	5
SwissProt Accessions	P84075, P32076, P41211, P70510	Gene names	Hpca
Domain Architecture	No domain graphic available
Description	Neuron-specific calcium-binding protein hippocalcin.

HPCL1_HUMAN
θ value	θ > 10 (rank : 48)	NC score	0.058583 (rank : 39)
Query Neighborhood Hits	30	Target Neighborhood Hits	150	Shared Neighborhood Hits	5
SwissProt Accessions	P37235, Q969S5	Gene names	HPCAL1, BDR1
Domain Architecture
Description	Hippocalcin-like protein 1 (Visinin-like protein 3) (VILIP-3) (Calcium-binding protein BDR-1) (HLP2).

HPCL1_MOUSE
θ value	θ > 10 (rank : 49)	NC score	0.060222 (rank : 33)
Query Neighborhood Hits	30	Target Neighborhood Hits	149	Shared Neighborhood Hits	5
SwissProt Accessions	P62748, P35333	Gene names	Hpcal1
Domain Architecture	No domain graphic available
Description	Hippocalcin-like protein 1 (Visinin-like protein 3) (VILIP-3) (Neural visinin-like protein 3) (NVL-3) (NVP-3).

KIP1_HUMAN
θ value	θ > 10 (rank : 50)	NC score	0.096389 (rank : 18)
Query Neighborhood Hits	30	Target Neighborhood Hits	105	Shared Neighborhood Hits	5
SwissProt Accessions	Q99828, O00693, O00735, Q6IB49, Q96J54, Q99971	Gene names	CIB1, CIB, KIP, PRKDCIP
Domain Architecture
Description	Calcium and integrin-binding protein 1 (Calmyrin) (DNA-PKcs- interacting protein) (Kinase-interacting protein) (KIP) (CIB) (SNK- interacting protein 2-28) (SIP2-28).

KIP1_MOUSE
θ value	θ > 10 (rank : 51)	NC score	0.105619 (rank : 15)
Query Neighborhood Hits	30	Target Neighborhood Hits	109	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z0F4, Q3TN80	Gene names	Cib1, Cib, Kip, Prkdcip
Domain Architecture
Description	Calcium and integrin-binding protein 1 (Calmyrin) (DNA-PKcs- interacting protein) (Kinase-interacting protein) (KIP) (CIB).

KPCL_HUMAN
θ value	θ > 10 (rank : 52)	NC score	0.053153 (rank : 49)
Query Neighborhood Hits	30	Target Neighborhood Hits	887	Shared Neighborhood Hits	20
SwissProt Accessions	P24723, Q16246	Gene names	PRKCH, PKCL
Domain Architecture
Description	Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta) (PKC-L).

KPCL_MOUSE
θ value	θ > 10 (rank : 53)	NC score	0.051195 (rank : 55)
Query Neighborhood Hits	30	Target Neighborhood Hits	891	Shared Neighborhood Hits	20
SwissProt Accessions	P23298	Gene names	Prkch, Pkch
Domain Architecture
Description	Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta) (PKC-L).

NCALD_HUMAN
θ value	θ > 10 (rank : 54)	NC score	0.061143 (rank : 31)
Query Neighborhood Hits	30	Target Neighborhood Hits	153	Shared Neighborhood Hits	5
SwissProt Accessions	P61601, P29554, Q8IYC3, Q9H0W2	Gene names	NCALD
Domain Architecture
Description	Neurocalcin delta.

NCALD_MOUSE
θ value	θ > 10 (rank : 55)	NC score	0.061143 (rank : 32)
Query Neighborhood Hits	30	Target Neighborhood Hits	153	Shared Neighborhood Hits	5
SwissProt Accessions	Q91X97, Q3TJS9, Q8BZN9	Gene names	Ncald, D15Ertd412e
Domain Architecture
Description	Neurocalcin delta.

PDZD8_HUMAN
θ value	θ > 10 (rank : 56)	NC score	0.062447 (rank : 30)
Query Neighborhood Hits	30	Target Neighborhood Hits	185	Shared Neighborhood Hits	13
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

RASF1_HUMAN
θ value	θ > 10 (rank : 57)	NC score	0.051789 (rank : 54)
Query Neighborhood Hits	30	Target Neighborhood Hits	62	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NS23, O14571, O60539, O60710, Q9HB04, Q9HB18, Q9NS22, Q9UND4, Q9UND5	Gene names	RASSF1, RDA32
Domain Architecture	No domain graphic available
Description	Ras association domain-containing protein 1.

RASF1_MOUSE
θ value	θ > 10 (rank : 58)	NC score	0.098069 (rank : 17)
Query Neighborhood Hits	30	Target Neighborhood Hits	74	Shared Neighborhood Hits	18
SwissProt Accessions	Q99MK9, Q9WUF5	Gene names	Rassf1
Domain Architecture	No domain graphic available
Description	Ras association domain-containing protein 1 (Protein 123F2).

STAC3_HUMAN
θ value	θ > 10 (rank : 59)	NC score	0.079926 (rank : 21)
Query Neighborhood Hits	30	Target Neighborhood Hits	228	Shared Neighborhood Hits	19
SwissProt Accessions	Q96MF2, Q96HU5	Gene names	STAC3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

STAC3_MOUSE
θ value	θ > 10 (rank : 60)	NC score	0.078819 (rank : 22)
Query Neighborhood Hits	30	Target Neighborhood Hits	232	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BZ71	Gene names	Stac3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

STAC_HUMAN
θ value	θ > 10 (rank : 61)	NC score	0.091766 (rank : 20)
Query Neighborhood Hits	30	Target Neighborhood Hits	276	Shared Neighborhood Hits	18
SwissProt Accessions	Q99469	Gene names	STAC
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

STAC_MOUSE
θ value	θ > 10 (rank : 62)	NC score	0.094343 (rank : 19)
Query Neighborhood Hits	30	Target Neighborhood Hits	268	Shared Neighborhood Hits	18
SwissProt Accessions	P97306	Gene names	Stac
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

UN13A_HUMAN
θ value	θ > 10 (rank : 63)	NC score	0.063600 (rank : 29)
Query Neighborhood Hits	30	Target Neighborhood Hits	285	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UPW8	Gene names	UNC13A, KIAA1032
Domain Architecture	No domain graphic available
Description	Unc-13 homolog A (Munc13-1).

UN13B_HUMAN
θ value	θ > 10 (rank : 64)	NC score	0.065202 (rank : 25)
Query Neighborhood Hits	30	Target Neighborhood Hits	217	Shared Neighborhood Hits	19
SwissProt Accessions	O14795	Gene names	UNC13B, UNC13
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

UN13B_MOUSE
θ value	θ > 10 (rank : 65)	NC score	0.058569 (rank : 40)
Query Neighborhood Hits	30	Target Neighborhood Hits	210	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Z1N9	Gene names	Unc13b, Unc13a
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

Hits sorted by NC score

DGKE_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	30	Target Neighborhood Hits	30	Shared Neighborhood Hits	30
SwissProt Accessions	Q9R1C6	Gene names	Dgke
Domain Architecture
Description	Diacylglycerol kinase epsilon (EC 2.7.1.107) (Diglyceride kinase epsilon) (DGK-epsilon) (DAG kinase epsilon).

DGKE_HUMAN
NC score	0.995351 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	30	Target Neighborhood Hits	32	Shared Neighborhood Hits	25
SwissProt Accessions	P52429, Q9UKQ3	Gene names	DGKE, DAGK5
Domain Architecture
Description	Diacylglycerol kinase epsilon (EC 2.7.1.107) (Diglyceride kinase epsilon) (DGK-epsilon) (DAG kinase epsilon).

DGKA_HUMAN
NC score	0.892328 (rank : 3)	θ value	6.10265e-73 (rank : 6)
Query Neighborhood Hits	30	Target Neighborhood Hits	151	Shared Neighborhood Hits	24
SwissProt Accessions	P23743, O75481, O75482, O75483	Gene names	DGKA, DAGK, DAGK1
Domain Architecture
Description	Diacylglycerol kinase alpha (EC 2.7.1.107) (Diglyceride kinase alpha) (DGK-alpha) (DAG kinase alpha) (80 kDa diacylglycerol kinase).

DGKA_MOUSE
NC score	0.887117 (rank : 4)	θ value	4.37348e-71 (rank : 7)
Query Neighborhood Hits	30	Target Neighborhood Hits	146	Shared Neighborhood Hits	22
SwissProt Accessions	O88673, Q922X2	Gene names	Dgka, Dagk1
Domain Architecture
Description	Diacylglycerol kinase alpha (EC 2.7.1.107) (Diglyceride kinase alpha) (DGK-alpha) (DAG kinase alpha) (80 kDa diacylglycerol kinase).

DGKG_HUMAN
NC score	0.872355 (rank : 5)	θ value	3.82246e-75 (rank : 4)
Query Neighborhood Hits	30	Target Neighborhood Hits	171	Shared Neighborhood Hits	24
SwissProt Accessions	P49619	Gene names	DGKG, DAGK3
Domain Architecture
Description	Diacylglycerol kinase gamma (EC 2.7.1.107) (Diglyceride kinase gamma) (DGK-gamma) (DAG kinase gamma).

DGKG_MOUSE
NC score	0.864318 (rank : 6)	θ value	2.73936e-73 (rank : 5)
Query Neighborhood Hits	30	Target Neighborhood Hits	188	Shared Neighborhood Hits	24
SwissProt Accessions	Q91WG7	Gene names	Dgkg, Dagk3
Domain Architecture
Description	Diacylglycerol kinase gamma (EC 2.7.1.107) (Diglyceride kinase gamma) (DGK-gamma) (DAG kinase gamma) (88 kDa diacylglycerol kinase).

DGKQ_HUMAN
NC score	0.860582 (rank : 7)	θ value	8.53533e-67 (rank : 8)
Query Neighborhood Hits	30	Target Neighborhood Hits	131	Shared Neighborhood Hits	24
SwissProt Accessions	P52824	Gene names	DGKQ, DAGK4
Domain Architecture
Description	Diacylglycerol kinase theta (EC 2.7.1.107) (Diglyceride kinase theta) (DGK-theta) (DAG kinase theta).

DGKB_HUMAN
NC score	0.836264 (rank : 8)	θ value	5.8972e-76 (rank : 3)
Query Neighborhood Hits	30	Target Neighborhood Hits	238	Shared Neighborhood Hits	24
SwissProt Accessions	Q9Y6T7, O75241, Q75MF9, Q75MU7, Q86UI5, Q86UM9, Q9UQ29	Gene names	DGKB, DAGK2, KIAA0718
Domain Architecture
Description	Diacylglycerol kinase beta (EC 2.7.1.107) (Diglyceride kinase beta) (DGK-beta) (DAG kinase beta) (90 kDa diacylglycerol kinase).

DGKZ_MOUSE
NC score	0.781439 (rank : 9)	θ value	1.7238e-59 (rank : 10)
Query Neighborhood Hits	30	Target Neighborhood Hits	542	Shared Neighborhood Hits	14
SwissProt Accessions	Q80UP3	Gene names	Dgkz
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

DGKD_HUMAN
NC score	0.778894 (rank : 10)	θ value	1.28137e-46 (rank : 13)
Query Neighborhood Hits	30	Target Neighborhood Hits	231	Shared Neighborhood Hits	24
SwissProt Accessions	Q16760, Q14158, Q6PK55, Q8NG53	Gene names	DGKD, KIAA0145
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase delta (EC 2.7.1.107) (Diglyceride kinase delta) (DGK-delta) (DAG kinase delta) (130 kDa diacylglycerol kinase).

DGKZ_HUMAN
NC score	0.776319 (rank : 11)	θ value	1.90589e-58 (rank : 11)
Query Neighborhood Hits	30	Target Neighborhood Hits	551	Shared Neighborhood Hits	14
SwissProt Accessions	Q13574, O00542	Gene names	DGKZ, DAGK6
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

DGKH_HUMAN
NC score	0.774397 (rank : 12)	θ value	2.58187e-47 (rank : 12)
Query Neighborhood Hits	30	Target Neighborhood Hits	255	Shared Neighborhood Hits	24
SwissProt Accessions	Q86XP1, Q5VZW0, Q6PI56, Q86XP2, Q8N3N0, Q8N7J9	Gene names	DGKH
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase eta (EC 2.7.1.107) (Diglyceride kinase eta) (DGK-eta) (DAG kinase eta).

DGKI_HUMAN
NC score	0.768362 (rank : 13)	θ value	4.10295e-61 (rank : 9)
Query Neighborhood Hits	30	Target Neighborhood Hits	609	Shared Neighborhood Hits	14
SwissProt Accessions	O75912, Q9NZ49	Gene names	DGKI
Domain Architecture
Description	Diacylglycerol kinase iota (EC 2.7.1.107) (Diglyceride kinase iota) (DGK-iota) (DAG kinase iota).

DGKK_HUMAN
NC score	0.766601 (rank : 14)	θ value	1.67352e-46 (rank : 14)
Query Neighborhood Hits	30	Target Neighborhood Hits	378	Shared Neighborhood Hits	20
SwissProt Accessions	Q5KSL6	Gene names	DGKK
Domain Architecture	No domain graphic available
Description	Diacylglycerol kinase kappa (EC 2.7.1.107) (Diglyceride kinase kappa) (DGK-kappa) (DAG kinase kappa) (142 kDa diacylglycerol kinase).

KIP1_MOUSE
NC score	0.105619 (rank : 15)	θ value	θ > 10 (rank : 51)
Query Neighborhood Hits	30	Target Neighborhood Hits	109	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z0F4, Q3TN80	Gene names	Cib1, Cib, Kip, Prkdcip
Domain Architecture
Description	Calcium and integrin-binding protein 1 (Calmyrin) (DNA-PKcs- interacting protein) (Kinase-interacting protein) (KIP) (CIB).

GRP3_HUMAN
NC score	0.100414 (rank : 16)	θ value	θ > 10 (rank : 40)
Query Neighborhood Hits	30	Target Neighborhood Hits	131	Shared Neighborhood Hits	17
SwissProt Accessions	Q8IV61, O94931	Gene names	RASGRP3, GRP3, KIAA0846
Domain Architecture
Description	RAS guanyl-releasing protein 3 (Calcium and DAG-regulated guanine nucleotide exchange factor III) (Guanine nucleotide exchange factor for Rap1).

RASF1_MOUSE
NC score	0.098069 (rank : 17)	θ value	θ > 10 (rank : 58)
Query Neighborhood Hits	30	Target Neighborhood Hits	74	Shared Neighborhood Hits	18
SwissProt Accessions	Q99MK9, Q9WUF5	Gene names	Rassf1
Domain Architecture	No domain graphic available
Description	Ras association domain-containing protein 1 (Protein 123F2).

KIP1_HUMAN
NC score	0.096389 (rank : 18)	θ value	θ > 10 (rank : 50)
Query Neighborhood Hits	30	Target Neighborhood Hits	105	Shared Neighborhood Hits	5
SwissProt Accessions	Q99828, O00693, O00735, Q6IB49, Q96J54, Q99971	Gene names	CIB1, CIB, KIP, PRKDCIP
Domain Architecture
Description	Calcium and integrin-binding protein 1 (Calmyrin) (DNA-PKcs- interacting protein) (Kinase-interacting protein) (KIP) (CIB) (SNK- interacting protein 2-28) (SIP2-28).

STAC_MOUSE
NC score	0.094343 (rank : 19)	θ value	θ > 10 (rank : 62)
Query Neighborhood Hits	30	Target Neighborhood Hits	268	Shared Neighborhood Hits	18
SwissProt Accessions	P97306	Gene names	Stac
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

STAC_HUMAN
NC score	0.091766 (rank : 20)	θ value	θ > 10 (rank : 61)
Query Neighborhood Hits	30	Target Neighborhood Hits	276	Shared Neighborhood Hits	18
SwissProt Accessions	Q99469	Gene names	STAC
Domain Architecture
Description	SH3 and cysteine-rich domain-containing protein (SRC homology 3 and cysteine-rich domain protein).

STAC3_HUMAN
NC score	0.079926 (rank : 21)	θ value	θ > 10 (rank : 59)
Query Neighborhood Hits	30	Target Neighborhood Hits	228	Shared Neighborhood Hits	19
SwissProt Accessions	Q96MF2, Q96HU5	Gene names	STAC3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

STAC3_MOUSE
NC score	0.078819 (rank : 22)	θ value	θ > 10 (rank : 60)
Query Neighborhood Hits	30	Target Neighborhood Hits	232	Shared Neighborhood Hits	18
SwissProt Accessions	Q8BZ71	Gene names	Stac3
Domain Architecture	No domain graphic available
Description	SH3 and cysteine-rich domain-containing protein 3.

CHIO_MOUSE
NC score	0.067522 (rank : 23)	θ value	5.27518 (rank : 27)
Query Neighborhood Hits	30	Target Neighborhood Hits	130	Shared Neighborhood Hits	18
SwissProt Accessions	Q80XD1, Q9D9W2, Q9ER57	Gene names	Chn2, Arhgap3, Bch
Domain Architecture	No domain graphic available
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

CHP2_MOUSE
NC score	0.066063 (rank : 24)	θ value	θ > 10 (rank : 38)
Query Neighborhood Hits	30	Target Neighborhood Hits	122	Shared Neighborhood Hits	5
SwissProt Accessions	Q9D869	Gene names	Chp2, Hca520
Domain Architecture
Description	Calcineurin B homologous protein 2 (Hepatocellular carcinoma- associated antigen 520 homolog).

UN13B_HUMAN
NC score	0.065202 (rank : 25)	θ value	θ > 10 (rank : 64)
Query Neighborhood Hits	30	Target Neighborhood Hits	217	Shared Neighborhood Hits	19
SwissProt Accessions	O14795	Gene names	UNC13B, UNC13
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

GUC1A_MOUSE
NC score	0.064690 (rank : 26)	θ value	θ > 10 (rank : 42)
Query Neighborhood Hits	30	Target Neighborhood Hits	152	Shared Neighborhood Hits	5
SwissProt Accessions	P43081	Gene names	Guca1a, Gcap, Gcap1, Guca1
Domain Architecture
Description	Guanylyl cyclase-activating protein 1 (GCAP 1) (Guanylate cyclase activator 1A).

GUC1A_HUMAN
NC score	0.064006 (rank : 27)	θ value	θ > 10 (rank : 41)
Query Neighborhood Hits	30	Target Neighborhood Hits	147	Shared Neighborhood Hits	5
SwissProt Accessions	P43080, Q9NU14	Gene names	GUCA1A, GCAP, GCAP1, GUCA1
Domain Architecture
Description	Guanylyl cyclase-activating protein 1 (GCAP 1) (Guanylate cyclase activator 1A).

CHIO_HUMAN
NC score	0.063876 (rank : 28)	θ value	5.27518 (rank : 26)
Query Neighborhood Hits	30	Target Neighborhood Hits	220	Shared Neighborhood Hits	18
SwissProt Accessions	P52757, Q75MM2	Gene names	CHN2, ARHGAP3, BCH
Domain Architecture
Description	Beta-chimaerin (Beta-chimerin) (Rho-GTPase-activating protein 3).

UN13A_HUMAN
NC score	0.063600 (rank : 29)	θ value	θ > 10 (rank : 63)
Query Neighborhood Hits	30	Target Neighborhood Hits	285	Shared Neighborhood Hits	17
SwissProt Accessions	Q9UPW8	Gene names	UNC13A, KIAA1032
Domain Architecture	No domain graphic available
Description	Unc-13 homolog A (Munc13-1).

PDZD8_HUMAN
NC score	0.062447 (rank : 30)	θ value	θ > 10 (rank : 56)
Query Neighborhood Hits	30	Target Neighborhood Hits	185	Shared Neighborhood Hits	13
SwissProt Accessions	Q8NEN9, Q86WE0, Q86WE5, Q9UFF1	Gene names	PDZD8, PDZK8
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 8 (Sarcoma antigen NY-SAR-84/NY-SAR- 104).

NCALD_HUMAN
NC score	0.061143 (rank : 31)	θ value	θ > 10 (rank : 54)
Query Neighborhood Hits	30	Target Neighborhood Hits	153	Shared Neighborhood Hits	5
SwissProt Accessions	P61601, P29554, Q8IYC3, Q9H0W2	Gene names	NCALD
Domain Architecture
Description	Neurocalcin delta.

NCALD_MOUSE
NC score	0.061143 (rank : 32)	θ value	θ > 10 (rank : 55)
Query Neighborhood Hits	30	Target Neighborhood Hits	153	Shared Neighborhood Hits	5
SwissProt Accessions	Q91X97, Q3TJS9, Q8BZN9	Gene names	Ncald, D15Ertd412e
Domain Architecture
Description	Neurocalcin delta.

HPCL1_MOUSE
NC score	0.060222 (rank : 33)	θ value	θ > 10 (rank : 49)
Query Neighborhood Hits	30	Target Neighborhood Hits	149	Shared Neighborhood Hits	5
SwissProt Accessions	P62748, P35333	Gene names	Hpcal1
Domain Architecture	No domain graphic available
Description	Hippocalcin-like protein 1 (Visinin-like protein 3) (VILIP-3) (Neural visinin-like protein 3) (NVL-3) (NVP-3).

HPCA_HUMAN
NC score	0.060035 (rank : 34)	θ value	θ > 10 (rank : 46)
Query Neighborhood Hits	30	Target Neighborhood Hits	156	Shared Neighborhood Hits	5
SwissProt Accessions	P84074, P32076, P41211, P70510	Gene names	HPCA, BDR2
Domain Architecture	No domain graphic available
Description	Neuron-specific calcium-binding protein hippocalcin (Calcium-binding protein BDR-2).

HPCA_MOUSE
NC score	0.060035 (rank : 35)	θ value	θ > 10 (rank : 47)
Query Neighborhood Hits	30	Target Neighborhood Hits	156	Shared Neighborhood Hits	5
SwissProt Accessions	P84075, P32076, P41211, P70510	Gene names	Hpca
Domain Architecture	No domain graphic available
Description	Neuron-specific calcium-binding protein hippocalcin.

CHIN_HUMAN
NC score	0.059731 (rank : 36)	θ value	θ > 10 (rank : 35)
Query Neighborhood Hits	30	Target Neighborhood Hits	227	Shared Neighborhood Hits	17
SwissProt Accessions	P15882, Q53SD6, Q53SH5, Q96FB0	Gene names	CHN1, ARHGAP2, CHN
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

CANB2_MOUSE
NC score	0.059083 (rank : 37)	θ value	θ > 10 (rank : 34)
Query Neighborhood Hits	30	Target Neighborhood Hits	173	Shared Neighborhood Hits	5
SwissProt Accessions	Q63811	Gene names	Ppp3r2
Domain Architecture
Description	Calcineurin subunit B isoform 2 (Protein phosphatase 2B regulatory subunit 2) (Protein phosphatase 3 regulatory subunit B beta isoform).

GUC1B_MOUSE
NC score	0.058737 (rank : 38)	θ value	θ > 10 (rank : 44)
Query Neighborhood Hits	30	Target Neighborhood Hits	116	Shared Neighborhood Hits	5
SwissProt Accessions	Q8VBV8	Gene names	Guca1b
Domain Architecture	No domain graphic available
Description	Guanylyl cyclase-activating protein 2 (GCAP 2) (Guanylate cyclase activator 1B).

HPCL1_HUMAN
NC score	0.058583 (rank : 39)	θ value	θ > 10 (rank : 48)
Query Neighborhood Hits	30	Target Neighborhood Hits	150	Shared Neighborhood Hits	5
SwissProt Accessions	P37235, Q969S5	Gene names	HPCAL1, BDR1
Domain Architecture
Description	Hippocalcin-like protein 1 (Visinin-like protein 3) (VILIP-3) (Calcium-binding protein BDR-1) (HLP2).

UN13B_MOUSE
NC score	0.058569 (rank : 40)	θ value	θ > 10 (rank : 65)
Query Neighborhood Hits	30	Target Neighborhood Hits	210	Shared Neighborhood Hits	18
SwissProt Accessions	Q9Z1N9	Gene names	Unc13b, Unc13a
Domain Architecture	No domain graphic available
Description	Unc-13 homolog B (Munc13-2) (munc13).

CHP2_HUMAN
NC score	0.058511 (rank : 41)	θ value	θ > 10 (rank : 37)
Query Neighborhood Hits	30	Target Neighborhood Hits	122	Shared Neighborhood Hits	5
SwissProt Accessions	O43745	Gene names	CHP2, HCA520
Domain Architecture
Description	Calcineurin B homologous protein 2 (Hepatocellular carcinoma- associated antigen 520).

GUC1B_HUMAN
NC score	0.057400 (rank : 42)	θ value	θ > 10 (rank : 43)
Query Neighborhood Hits	30	Target Neighborhood Hits	124	Shared Neighborhood Hits	5
SwissProt Accessions	Q9UMX6, Q9NU15	Gene names	GUCA1B, GCAP2
Domain Architecture
Description	Guanylyl cyclase-activating protein 2 (GCAP 2) (Guanylate cyclase activator 1B).

CHIN_MOUSE
NC score	0.055802 (rank : 43)	θ value	θ > 10 (rank : 36)
Query Neighborhood Hits	30	Target Neighborhood Hits	229	Shared Neighborhood Hits	17
SwissProt Accessions	Q91V57, Q3UGY3, Q7TQE5, Q8BWU6, Q9D9B3	Gene names	Chn1, Arhgap2
Domain Architecture
Description	N-chimaerin (NC) (N-chimerin) (Alpha chimerin) (A-chimaerin) (Rho- GTPase-activating protein 2).

CANB1_MOUSE
NC score	0.055122 (rank : 44)	θ value	θ > 10 (rank : 32)
Query Neighborhood Hits	30	Target Neighborhood Hits	183	Shared Neighborhood Hits	5
SwissProt Accessions	Q63810	Gene names	Ppp3r1, Cnb
Domain Architecture
Description	Calcineurin subunit B isoform 1 (Protein phosphatase 2B regulatory subunit 1) (Protein phosphatase 3 regulatory subunit B alpha isoform 1).

CANB1_HUMAN
NC score	0.055117 (rank : 45)	θ value	θ > 10 (rank : 31)
Query Neighborhood Hits	30	Target Neighborhood Hits	183	Shared Neighborhood Hits	5
SwissProt Accessions	P63098, P06705, P15117, Q08044	Gene names	PPP3R1, CNA2, CNB
Domain Architecture	No domain graphic available
Description	Calcineurin subunit B isoform 1 (Protein phosphatase 2B regulatory subunit 1) (Protein phosphatase 3 regulatory subunit B alpha isoform 1).

KPCD_MOUSE
NC score	0.054454 (rank : 46)	θ value	0.125558 (rank : 17)
Query Neighborhood Hits	30	Target Neighborhood Hits	888	Shared Neighborhood Hits	21
SwissProt Accessions	P28867, Q91V85, Q9Z333	Gene names	Prkcd, Pkcd
Domain Architecture
Description	Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta).

KPCD_HUMAN
NC score	0.054099 (rank : 47)	θ value	0.163984 (rank : 18)
Query Neighborhood Hits	30	Target Neighborhood Hits	900	Shared Neighborhood Hits	21
SwissProt Accessions	Q05655, Q15144	Gene names	PRKCD
Domain Architecture
Description	Protein kinase C delta type (EC 2.7.11.13) (nPKC-delta).

CANB2_HUMAN
NC score	0.053471 (rank : 48)	θ value	θ > 10 (rank : 33)
Query Neighborhood Hits	30	Target Neighborhood Hits	163	Shared Neighborhood Hits	5
SwissProt Accessions	Q96LZ3, Q7Z4V8, Q8WYJ4	Gene names	PPP3R2, CBLP
Domain Architecture	No domain graphic available
Description	Calcineurin subunit B isoform 2 (Protein phosphatase 2B regulatory subunit 2) (Protein phosphatase 3 regulatory subunit B beta isoform) (Calcineurin B-like protein) (CBLP) (CNBII).

KPCL_HUMAN
NC score	0.053153 (rank : 49)	θ value	θ > 10 (rank : 52)
Query Neighborhood Hits	30	Target Neighborhood Hits	887	Shared Neighborhood Hits	20
SwissProt Accessions	P24723, Q16246	Gene names	PRKCH, PKCL
Domain Architecture
Description	Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta) (PKC-L).

GUC1C_HUMAN
NC score	0.053075 (rank : 50)	θ value	θ > 10 (rank : 45)
Query Neighborhood Hits	30	Target Neighborhood Hits	148	Shared Neighborhood Hits	5
SwissProt Accessions	O95843, O95844, Q9UNM0	Gene names	GUCA1C, GCAP3
Domain Architecture
Description	Guanylyl cyclase-activating protein 3 (GCAP 3) (Guanylate cyclase activator 1C).

EFHD1_HUMAN
NC score	0.052407 (rank : 51)	θ value	θ > 10 (rank : 39)
Query Neighborhood Hits	30	Target Neighborhood Hits	108	Shared Neighborhood Hits	5
SwissProt Accessions	Q9BUP0, Q9BTF8, Q9H8I2, Q9HBQ0	Gene names	EFHD1, SWS2
Domain Architecture
Description	EF-hand domain-containing protein 1 (Swiprosin-2).

KPCT_MOUSE
NC score	0.052354 (rank : 52)	θ value	0.0563607 (rank : 16)
Query Neighborhood Hits	30	Target Neighborhood Hits	895	Shared Neighborhood Hits	21
SwissProt Accessions	Q02111	Gene names	Prkcq, Pkcq
Domain Architecture
Description	Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta).

KPCT_HUMAN
NC score	0.052130 (rank : 53)	θ value	0.0563607 (rank : 15)
Query Neighborhood Hits	30	Target Neighborhood Hits	897	Shared Neighborhood Hits	21
SwissProt Accessions	Q04759, Q3MJF1, Q64FY5, Q9H508, Q9H549	Gene names	PRKCQ, PRKCT
Domain Architecture
Description	Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta).

RASF1_HUMAN
NC score	0.051789 (rank : 54)	θ value	θ > 10 (rank : 57)
Query Neighborhood Hits	30	Target Neighborhood Hits	62	Shared Neighborhood Hits	14
SwissProt Accessions	Q9NS23, O14571, O60539, O60710, Q9HB04, Q9HB18, Q9NS22, Q9UND4, Q9UND5	Gene names	RASSF1, RDA32
Domain Architecture	No domain graphic available
Description	Ras association domain-containing protein 1.

KPCL_MOUSE
NC score	0.051195 (rank : 55)	θ value	θ > 10 (rank : 53)
Query Neighborhood Hits	30	Target Neighborhood Hits	891	Shared Neighborhood Hits	20
SwissProt Accessions	P23298	Gene names	Prkch, Pkch
Domain Architecture
Description	Protein kinase C eta type (EC 2.7.11.13) (nPKC-eta) (PKC-L).

KPCG_HUMAN
NC score	0.048455 (rank : 56)	θ value	2.36792 (rank : 22)
Query Neighborhood Hits	30	Target Neighborhood Hits	1126	Shared Neighborhood Hits	21
SwissProt Accessions	P05129	Gene names	PRKCG, PKCG
Domain Architecture
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

KPCG_MOUSE
NC score	0.048098 (rank : 57)	θ value	2.36792 (rank : 23)
Query Neighborhood Hits	30	Target Neighborhood Hits	1123	Shared Neighborhood Hits	21
SwissProt Accessions	P63318, P05697	Gene names	Prkcg, Pkcc, Pkcg, Prkcc
Domain Architecture	No domain graphic available
Description	Protein kinase C gamma type (EC 2.7.11.13) (PKC-gamma).

PHF14_MOUSE
NC score	0.022846 (rank : 58)	θ value	1.81305 (rank : 21)
Query Neighborhood Hits	30	Target Neighborhood Hits	342	Shared Neighborhood Hits	6
SwissProt Accessions	Q9D4H9, Q810Z6, Q8C284, Q8CGF8, Q9D1Q8	Gene names	Phf14
Domain Architecture
Description	PHD finger protein 14.

PHF14_HUMAN
NC score	0.022146 (rank : 59)	θ value	1.81305 (rank : 20)
Query Neighborhood Hits	30	Target Neighborhood Hits	447	Shared Neighborhood Hits	6
SwissProt Accessions	O94880	Gene names	PHF14, KIAA0783
Domain Architecture	No domain graphic available
Description	PHD finger protein 14.

RAF1_MOUSE
NC score	0.019995 (rank : 60)	θ value	5.27518 (rank : 29)
Query Neighborhood Hits	30	Target Neighborhood Hits	886	Shared Neighborhood Hits	20
SwissProt Accessions	Q99N57, Q91WH1	Gene names	Raf1, Craf
Domain Architecture
Description	RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf- 1) (C-RAF) (cRaf).

RAF1_HUMAN
NC score	0.019916 (rank : 61)	θ value	5.27518 (rank : 28)
Query Neighborhood Hits	30	Target Neighborhood Hits	886	Shared Neighborhood Hits	20
SwissProt Accessions	P04049	Gene names	RAF1, RAF
Domain Architecture
Description	RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Raf- 1) (C-RAF) (cRaf).

BRD1_HUMAN
NC score	0.015650 (rank : 62)	θ value	1.38821 (rank : 19)
Query Neighborhood Hits	30	Target Neighborhood Hits	188	Shared Neighborhood Hits	5
SwissProt Accessions	O95696	Gene names	BRD1, BRL, BRPF2
Domain Architecture
Description	Bromodomain-containing protein 1 (BR140-like protein).

BRPF3_HUMAN
NC score	0.015613 (rank : 63)	θ value	8.99809 (rank : 30)
Query Neighborhood Hits	30	Target Neighborhood Hits	217	Shared Neighborhood Hits	6
SwissProt Accessions	Q9ULD4, Q5R3K8	Gene names	BRPF3, KIAA1286
Domain Architecture	No domain graphic available
Description	Bromodomain and PHD finger-containing protein 3.

ZNFX1_MOUSE
NC score	0.015197 (rank : 64)	θ value	2.36792 (rank : 24)
Query Neighborhood Hits	30	Target Neighborhood Hits	407	Shared Neighborhood Hits	3
SwissProt Accessions	Q8R151, Q3U016, Q3UD71, Q3UEZ0	Gene names	ZNFX1
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.

ZNFX1_HUMAN
NC score	0.014489 (rank : 65)	θ value	4.03905 (rank : 25)
Query Neighborhood Hits	30	Target Neighborhood Hits	308	Shared Neighborhood Hits	3
SwissProt Accessions	Q9P2E3, Q9BQM7, Q9BQM8, Q9H8C1, Q9H9S2, Q9NUM1, Q9NWW1	Gene names	ZNFX1, KIAA1404
Domain Architecture	No domain graphic available
Description	NFX1-type zinc finger-containing protein 1.