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Network neighborhood for query Sequence : SPHK2_MOUSE

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SPHK2_MOUSE
SwissProt Accessions	Q9JIA7, Q91VA9, Q9DBH6	Gene names	Sphk2
Domain Architecture
Description	Sphingosine kinase 2 (EC 2.7.1.-) (SK 2) (SPK 2).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

SPHK2_HUMAN
θ value	0 (rank : 1)	NC score	0.978938 (rank : 2)
Query Neighborhood Hits	78	Target Neighborhood Hits	81	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NRA0, Q9BRN1, Q9H0Q2, Q9NWU7	Gene names	SPHK2
Domain Architecture
Description	Sphingosine kinase 2 (EC 2.7.1.-) (SK 2) (SPK 2).

SPHK2_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	78	Target Neighborhood Hits	78	Shared Neighborhood Hits	78
SwissProt Accessions	Q9JIA7, Q91VA9, Q9DBH6	Gene names	Sphk2
Domain Architecture
Description	Sphingosine kinase 2 (EC 2.7.1.-) (SK 2) (SPK 2).

SPHK1_HUMAN
θ value	1.01059e-59 (rank : 3)	NC score	0.903254 (rank : 3)
Query Neighborhood Hits	78	Target Neighborhood Hits	15	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NYA1, Q9HD92, Q9NY70, Q9NYL3	Gene names	SPHK1, SPHK, SPK
Domain Architecture
Description	Sphingosine kinase 1 (EC 2.7.1.-) (SK 1) (SPK 1).

CERK1_HUMAN
θ value	3.17815e-21 (rank : 4)	NC score	0.647346 (rank : 4)
Query Neighborhood Hits	78	Target Neighborhood Hits	10	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TCT0, Q9BYB3, Q9UGE5	Gene names	CERK, KIAA1646
Domain Architecture
Description	Ceramide kinase (EC 2.7.1.138) (Acylsphingosine kinase) (hCERK) (Lipid kinase 4) (LK4).

CERK1_MOUSE
θ value	1.13037e-18 (rank : 5)	NC score	0.632921 (rank : 5)
Query Neighborhood Hits	78	Target Neighborhood Hits	17	Shared Neighborhood Hits	8
SwissProt Accessions	Q8K4Q7	Gene names	Cerk
Domain Architecture
Description	Ceramide kinase (EC 2.7.1.138) (Acylsphingosine kinase) (mCERK).

MULK_HUMAN
θ value	3.52202e-12 (rank : 6)	NC score	0.560344 (rank : 6)
Query Neighborhood Hits	78	Target Neighborhood Hits	13	Shared Neighborhood Hits	9
SwissProt Accessions	Q53H12, Q75KN1, Q96GC3, Q9NP48	Gene names	MULK, AGK
Domain Architecture	No domain graphic available
Description	Multiple substrate lipid kinase, mitochondrial precursor (EC 2.7.1.94) (EC 2.7.1.107) (Multi-substrate lipid kinase) (MuLK) (HsMuLK) (Acylglycerol kinase) (hAGK).

MULK_MOUSE
θ value	1.02475e-11 (rank : 7)	NC score	0.556524 (rank : 7)
Query Neighborhood Hits	78	Target Neighborhood Hits	10	Shared Neighborhood Hits	9
SwissProt Accessions	Q9ESW4, Q9D087	Gene names	Mulk
Domain Architecture	No domain graphic available
Description	Multiple substrate lipid kinase, mitochondrial precursor (EC 2.7.1.94) (EC 2.7.1.107) (Multi-substrate lipid kinase) (MuLK).

CERKL_HUMAN
θ value	5.44631e-05 (rank : 8)	NC score	0.450351 (rank : 8)
Query Neighborhood Hits	78	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	Q49MI3, Q49MH9, Q49MI0, Q49MI1, Q49MI2, Q5DVJ2, Q5DVJ4, Q5DVJ5, Q6UZF6, Q6ZP59	Gene names	CERKL
Domain Architecture	No domain graphic available
Description	Ceramide kinase-like protein.

PRRT3_HUMAN
θ value	0.00665767 (rank : 9)	NC score	0.085803 (rank : 9)
Query Neighborhood Hits	78	Target Neighborhood Hits	998	Shared Neighborhood Hits	32
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

SMAL1_MOUSE
θ value	0.0961366 (rank : 10)	NC score	0.044319 (rank : 28)
Query Neighborhood Hits	78	Target Neighborhood Hits	157	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BJL0, Q8BVK7, Q8BXW4, Q8K309, Q9EQK8, Q9QYC4	Gene names	Smarcal1, Harp
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (mharp).

SON_HUMAN
θ value	0.125558 (rank : 11)	NC score	0.043827 (rank : 29)
Query Neighborhood Hits	78	Target Neighborhood Hits	1568	Shared Neighborhood Hits	39
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

ZN385_HUMAN
θ value	0.125558 (rank : 12)	NC score	0.060763 (rank : 13)
Query Neighborhood Hits	78	Target Neighborhood Hits	614	Shared Neighborhood Hits	22
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

NRX2A_HUMAN
θ value	0.21417 (rank : 13)	NC score	0.039557 (rank : 31)
Query Neighborhood Hits	78	Target Neighborhood Hits	614	Shared Neighborhood Hits	20
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

NRX2B_HUMAN
θ value	0.21417 (rank : 14)	NC score	0.055468 (rank : 14)
Query Neighborhood Hits	78	Target Neighborhood Hits	481	Shared Neighborhood Hits	19
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

ABRA_HUMAN
θ value	0.279714 (rank : 15)	NC score	0.053566 (rank : 16)
Query Neighborhood Hits	78	Target Neighborhood Hits	52	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N0Z2	Gene names	ABRA
Domain Architecture	No domain graphic available
Description	Actin-binding Rho-activating protein (Striated muscle activator of Rho-dependent signaling) (STARS).

DGKI_HUMAN
θ value	0.279714 (rank : 16)	NC score	0.073327 (rank : 11)
Query Neighborhood Hits	78	Target Neighborhood Hits	609	Shared Neighborhood Hits	12
SwissProt Accessions	O75912, Q9NZ49	Gene names	DGKI
Domain Architecture
Description	Diacylglycerol kinase iota (EC 2.7.1.107) (Diglyceride kinase iota) (DGK-iota) (DAG kinase iota).

MEF2D_HUMAN
θ value	0.365318 (rank : 17)	NC score	0.044702 (rank : 26)
Query Neighborhood Hits	78	Target Neighborhood Hits	170	Shared Neighborhood Hits	9
SwissProt Accessions	Q14814, Q14815	Gene names	MEF2D
Domain Architecture
Description	Myocyte-specific enhancer factor 2D.

MEF2D_MOUSE
θ value	0.365318 (rank : 18)	NC score	0.044910 (rank : 24)
Query Neighborhood Hits	78	Target Neighborhood Hits	146	Shared Neighborhood Hits	9
SwissProt Accessions	Q63943, Q63944	Gene names	Mef2d
Domain Architecture
Description	Myocyte-specific enhancer factor 2D.

CXX1_HUMAN
θ value	0.47712 (rank : 19)	NC score	0.084537 (rank : 10)
Query Neighborhood Hits	78	Target Neighborhood Hits	17	Shared Neighborhood Hits	4
SwissProt Accessions	O15255	Gene names	CXX1
Domain Architecture	No domain graphic available
Description	CAAX box protein 1 (Cerebral protein 5).

DGKA_HUMAN
θ value	0.47712 (rank : 20)	NC score	0.054499 (rank : 15)
Query Neighborhood Hits	78	Target Neighborhood Hits	151	Shared Neighborhood Hits	8
SwissProt Accessions	P23743, O75481, O75482, O75483	Gene names	DGKA, DAGK, DAGK1
Domain Architecture
Description	Diacylglycerol kinase alpha (EC 2.7.1.107) (Diglyceride kinase alpha) (DGK-alpha) (DAG kinase alpha) (80 kDa diacylglycerol kinase).

RBM12_HUMAN
θ value	0.62314 (rank : 21)	NC score	0.050426 (rank : 18)
Query Neighborhood Hits	78	Target Neighborhood Hits	298	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NTZ6, O94865, Q8N3B1, Q9H196	Gene names	RBM12, KIAA0765
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

SF3B4_HUMAN
θ value	0.62314 (rank : 22)	NC score	0.027093 (rank : 37)
Query Neighborhood Hits	78	Target Neighborhood Hits	445	Shared Neighborhood Hits	17
SwissProt Accessions	Q15427	Gene names	SF3B4, SAP49
Domain Architecture
Description	Splicing factor 3B subunit 4 (Spliceosome-associated protein 49) (SAP 49) (SF3b50) (Pre-mRNA-splicing factor SF3b 49 kDa subunit).

BCL9_HUMAN
θ value	1.06291 (rank : 23)	NC score	0.044364 (rank : 27)
Query Neighborhood Hits	78	Target Neighborhood Hits	1008	Shared Neighborhood Hits	36
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

CSKI2_HUMAN
θ value	1.06291 (rank : 24)	NC score	0.021053 (rank : 42)
Query Neighborhood Hits	78	Target Neighborhood Hits	747	Shared Neighborhood Hits	23
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

SCAP_HUMAN
θ value	1.06291 (rank : 25)	NC score	0.025309 (rank : 38)
Query Neighborhood Hits	78	Target Neighborhood Hits	368	Shared Neighborhood Hits	8
SwissProt Accessions	Q12770, Q8N2E0, Q8WUA1	Gene names	SCAP, KIAA0199
Domain Architecture
Description	Sterol regulatory element-binding protein cleavage-activating protein (SREBP cleavage-activating protein) (SCAP).

YLPM1_MOUSE
θ value	1.06291 (rank : 26)	NC score	0.043608 (rank : 30)
Query Neighborhood Hits	78	Target Neighborhood Hits	505	Shared Neighborhood Hits	20
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

DGKG_HUMAN
θ value	1.38821 (rank : 27)	NC score	0.052384 (rank : 17)
Query Neighborhood Hits	78	Target Neighborhood Hits	171	Shared Neighborhood Hits	8
SwissProt Accessions	P49619	Gene names	DGKG, DAGK3
Domain Architecture
Description	Diacylglycerol kinase gamma (EC 2.7.1.107) (Diglyceride kinase gamma) (DGK-gamma) (DAG kinase gamma).

NIBL_HUMAN
θ value	1.38821 (rank : 28)	NC score	0.030556 (rank : 36)
Query Neighborhood Hits	78	Target Neighborhood Hits	61	Shared Neighborhood Hits	4
SwissProt Accessions	Q96TA1, Q9BUS2, Q9NT35	Gene names	C9orf88
Domain Architecture	No domain graphic available
Description	Niban-like protein (Meg-3).

EPHB6_HUMAN
θ value	1.81305 (rank : 29)	NC score	0.004220 (rank : 71)
Query Neighborhood Hits	78	Target Neighborhood Hits	912	Shared Neighborhood Hits	9
SwissProt Accessions	O15197	Gene names	EPHB6
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP).

LPP_HUMAN
θ value	1.81305 (rank : 30)	NC score	0.021306 (rank : 41)
Query Neighborhood Hits	78	Target Neighborhood Hits	775	Shared Neighborhood Hits	26
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

PDZD2_HUMAN
θ value	1.81305 (rank : 31)	NC score	0.019133 (rank : 45)
Query Neighborhood Hits	78	Target Neighborhood Hits	772	Shared Neighborhood Hits	18
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

RBM12_MOUSE
θ value	1.81305 (rank : 32)	NC score	0.046934 (rank : 23)
Query Neighborhood Hits	78	Target Neighborhood Hits	313	Shared Neighborhood Hits	16
SwissProt Accessions	Q8R4X3, Q8K373, Q8R302, Q9CS80	Gene names	Rbm12
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

SPEG_HUMAN
θ value	1.81305 (rank : 33)	NC score	0.006338 (rank : 70)
Query Neighborhood Hits	78	Target Neighborhood Hits	1762	Shared Neighborhood Hits	27
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

ZBTB3_HUMAN
θ value	1.81305 (rank : 34)	NC score	0.009685 (rank : 63)
Query Neighborhood Hits	78	Target Neighborhood Hits	910	Shared Neighborhood Hits	14
SwissProt Accessions	Q9H5J0	Gene names	ZBTB3
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 3.

DGKZ_HUMAN
θ value	2.36792 (rank : 35)	NC score	0.049116 (rank : 20)
Query Neighborhood Hits	78	Target Neighborhood Hits	551	Shared Neighborhood Hits	9
SwissProt Accessions	Q13574, O00542	Gene names	DGKZ, DAGK6
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

DGKZ_MOUSE
θ value	2.36792 (rank : 36)	NC score	0.049527 (rank : 19)
Query Neighborhood Hits	78	Target Neighborhood Hits	542	Shared Neighborhood Hits	9
SwissProt Accessions	Q80UP3	Gene names	Dgkz
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

HIC1_HUMAN
θ value	2.36792 (rank : 37)	NC score	0.003355 (rank : 75)
Query Neighborhood Hits	78	Target Neighborhood Hits	838	Shared Neighborhood Hits	12
SwissProt Accessions	Q14526	Gene names	HIC1, ZBTB29
Domain Architecture
Description	Hypermethylated in cancer 1 protein (Hic-1) (Zinc finger and BTB domain-containing protein 29).

PI5PA_HUMAN
θ value	2.36792 (rank : 38)	NC score	0.036748 (rank : 32)
Query Neighborhood Hits	78	Target Neighborhood Hits	749	Shared Neighborhood Hits	37
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

PRRT3_MOUSE
θ value	2.36792 (rank : 39)	NC score	0.067677 (rank : 12)
Query Neighborhood Hits	78	Target Neighborhood Hits	162	Shared Neighborhood Hits	8
SwissProt Accessions	Q6PE13	Gene names	Prrt3
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

ACINU_HUMAN
θ value	3.0926 (rank : 40)	NC score	0.017060 (rank : 50)
Query Neighborhood Hits	78	Target Neighborhood Hits	828	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

BRSK1_HUMAN
θ value	3.0926 (rank : 41)	NC score	0.002252 (rank : 77)
Query Neighborhood Hits	78	Target Neighborhood Hits	942	Shared Neighborhood Hits	11
SwissProt Accessions	Q8TDC3, Q5J5B5, Q8NDD0, Q8NDR4, Q8TDC2, Q96AV4, Q96JL4	Gene names	BRSK1, KIAA1811, SAD1
Domain Architecture
Description	BR serine/threonine-protein kinase 1 (EC 2.7.11.1) (SAD1 kinase) (SAD1A).

CAC1B_MOUSE
θ value	3.0926 (rank : 42)	NC score	0.012850 (rank : 56)
Query Neighborhood Hits	78	Target Neighborhood Hits	351	Shared Neighborhood Hits	10
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

HSF4_MOUSE
θ value	3.0926 (rank : 43)	NC score	0.019361 (rank : 44)
Query Neighborhood Hits	78	Target Neighborhood Hits	57	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R0L1, Q9R0L2	Gene names	Hsf4
Domain Architecture
Description	Heat shock factor protein 4 (HSF 4) (Heat shock transcription factor 4) (HSTF 4) (mHSF4).

PLXB1_MOUSE
θ value	3.0926 (rank : 44)	NC score	0.010530 (rank : 60)
Query Neighborhood Hits	78	Target Neighborhood Hits	259	Shared Neighborhood Hits	6
SwissProt Accessions	Q8CJH3, Q6ZQC3, Q80ZZ1	Gene names	Plxnb1, Kiaa0407
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor.

ATN1_HUMAN
θ value	4.03905 (rank : 45)	NC score	0.031079 (rank : 35)
Query Neighborhood Hits	78	Target Neighborhood Hits	676	Shared Neighborhood Hits	18
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

BCL9_MOUSE
θ value	4.03905 (rank : 46)	NC score	0.044823 (rank : 25)
Query Neighborhood Hits	78	Target Neighborhood Hits	770	Shared Neighborhood Hits	33
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

DGKG_MOUSE
θ value	4.03905 (rank : 47)	NC score	0.047926 (rank : 22)
Query Neighborhood Hits	78	Target Neighborhood Hits	188	Shared Neighborhood Hits	8
SwissProt Accessions	Q91WG7	Gene names	Dgkg, Dagk3
Domain Architecture
Description	Diacylglycerol kinase gamma (EC 2.7.1.107) (Diglyceride kinase gamma) (DGK-gamma) (DAG kinase gamma) (88 kDa diacylglycerol kinase).

SAM68_HUMAN
θ value	4.03905 (rank : 48)	NC score	0.017460 (rank : 48)
Query Neighborhood Hits	78	Target Neighborhood Hits	68	Shared Neighborhood Hits	4
SwissProt Accessions	Q07666, Q6PJX7, Q8NB97, Q99760	Gene names	KHDRBS1, SAM68
Domain Architecture	No domain graphic available
Description	KH domain-containing, RNA-binding, signal transduction-associated protein 1 (p21 Ras GTPase-activating protein-associated p62) (GAP- associated tyrosine phosphoprotein p62) (Src-associated in mitosis 68 kDa protein) (Sam68) (p68).

TAF3_HUMAN
θ value	4.03905 (rank : 49)	NC score	0.017812 (rank : 47)
Query Neighborhood Hits	78	Target Neighborhood Hits	568	Shared Neighborhood Hits	13
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

ATBF1_MOUSE
θ value	5.27518 (rank : 50)	NC score	0.010395 (rank : 61)
Query Neighborhood Hits	78	Target Neighborhood Hits	1841	Shared Neighborhood Hits	29
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

CABL1_HUMAN
θ value	5.27518 (rank : 51)	NC score	0.015348 (rank : 51)
Query Neighborhood Hits	78	Target Neighborhood Hits	37	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TDN4, Q8N3Y8, Q8NA22, Q9BTG1	Gene names	CABLES1, CABLES
Domain Architecture	No domain graphic available
Description	CDK5 and ABL1 enzyme substrate 1 (Interactor with CDK3 1) (Ik3-1).

FMNL_HUMAN
θ value	5.27518 (rank : 52)	NC score	0.024719 (rank : 39)
Query Neighborhood Hits	78	Target Neighborhood Hits	529	Shared Neighborhood Hits	20
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

PRAM5_HUMAN
θ value	5.27518 (rank : 53)	NC score	0.013552 (rank : 55)
Query Neighborhood Hits	78	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	Q5TYX0	Gene names	PRAMEF5
Domain Architecture	No domain graphic available
Description	PRAME family member 5.

PRAM6_HUMAN
θ value	5.27518 (rank : 54)	NC score	0.013557 (rank : 54)
Query Neighborhood Hits	78	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	Q5VXH4	Gene names	PRAMEF6
Domain Architecture	No domain graphic available
Description	PRAME family member 6.

RSMB_HUMAN
θ value	5.27518 (rank : 55)	NC score	0.035547 (rank : 33)
Query Neighborhood Hits	78	Target Neighborhood Hits	117	Shared Neighborhood Hits	17
SwissProt Accessions	P14678, Q15490, Q9UIS5	Gene names	SNRPB, COD, SNRPB1
Domain Architecture
Description	Small nuclear ribonucleoprotein-associated proteins B and B' (snRNP-B) (Sm protein B/B') (Sm-B/Sm-B') (SmB/SmB').

RSMB_MOUSE
θ value	5.27518 (rank : 56)	NC score	0.033631 (rank : 34)
Query Neighborhood Hits	78	Target Neighborhood Hits	93	Shared Neighborhood Hits	14
SwissProt Accessions	P27048, Q3UJT1	Gene names	Snrpb
Domain Architecture
Description	Small nuclear ribonucleoprotein-associated protein B (snRNP-B) (Sm protein B) (Sm-B) (SmB).

SMR3A_HUMAN
θ value	5.27518 (rank : 57)	NC score	0.048405 (rank : 21)
Query Neighborhood Hits	78	Target Neighborhood Hits	93	Shared Neighborhood Hits	11
SwissProt Accessions	Q99954	Gene names	SMR3A, PBI, PROL5
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog A precursor (Proline-rich protein 5) (Proline-rich protein PBI).

Z3H7A_HUMAN
θ value	5.27518 (rank : 58)	NC score	0.018923 (rank : 46)
Query Neighborhood Hits	78	Target Neighborhood Hits	105	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IWR0, Q9NPE9	Gene names	ZC3H7A, ZC3H7, ZC3HDC7
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH-type domain-containing protein 7A.

ZN687_HUMAN
θ value	5.27518 (rank : 59)	NC score	0.007462 (rank : 67)
Query Neighborhood Hits	78	Target Neighborhood Hits	1244	Shared Neighborhood Hits	27
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

ATOH1_MOUSE
θ value	6.88961 (rank : 60)	NC score	0.010571 (rank : 59)
Query Neighborhood Hits	78	Target Neighborhood Hits	100	Shared Neighborhood Hits	2
SwissProt Accessions	P48985	Gene names	Atoh1, Ath1
Domain Architecture
Description	Atonal protein homolog 1 (Helix-loop-helix protein mATH-1) (MATH1).

CAC1G_HUMAN
θ value	6.88961 (rank : 61)	NC score	0.012581 (rank : 58)
Query Neighborhood Hits	78	Target Neighborhood Hits	587	Shared Neighborhood Hits	21
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

CBP_MOUSE
θ value	6.88961 (rank : 62)	NC score	0.023763 (rank : 40)
Query Neighborhood Hits	78	Target Neighborhood Hits	1051	Shared Neighborhood Hits	31
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

FBLN2_MOUSE
θ value	6.88961 (rank : 63)	NC score	0.006585 (rank : 68)
Query Neighborhood Hits	78	Target Neighborhood Hits	505	Shared Neighborhood Hits	14
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

FOXK1_MOUSE
θ value	6.88961 (rank : 64)	NC score	0.006472 (rank : 69)
Query Neighborhood Hits	78	Target Neighborhood Hits	215	Shared Neighborhood Hits	8
SwissProt Accessions	P42128, O35939	Gene names	Foxk1, Mnf
Domain Architecture
Description	Forkhead box protein K1 (Myocyte nuclear factor) (MNF).

MAML3_HUMAN
θ value	6.88961 (rank : 65)	NC score	0.017127 (rank : 49)
Query Neighborhood Hits	78	Target Neighborhood Hits	323	Shared Neighborhood Hits	10
SwissProt Accessions	Q96JK9	Gene names	MAML3, KIAA1816
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 3 (Mam-3).

MK07_HUMAN
θ value	6.88961 (rank : 66)	NC score	0.003060 (rank : 76)
Query Neighborhood Hits	78	Target Neighborhood Hits	1087	Shared Neighborhood Hits	17
SwissProt Accessions	Q13164, Q16634	Gene names	MAPK7, ERK4, ERK5, PRKM7
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (ERK4) (BMK1 kinase).

PGCA_HUMAN
θ value	6.88961 (rank : 67)	NC score	0.012829 (rank : 57)
Query Neighborhood Hits	78	Target Neighborhood Hits	821	Shared Neighborhood Hits	17
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

PGCA_MOUSE
θ value	6.88961 (rank : 68)	NC score	0.014172 (rank : 53)
Query Neighborhood Hits	78	Target Neighborhood Hits	643	Shared Neighborhood Hits	12
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

PO121_MOUSE
θ value	6.88961 (rank : 69)	NC score	0.019916 (rank : 43)
Query Neighborhood Hits	78	Target Neighborhood Hits	345	Shared Neighborhood Hits	12
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

SP5_HUMAN
θ value	6.88961 (rank : 70)	NC score	0.003800 (rank : 73)
Query Neighborhood Hits	78	Target Neighborhood Hits	832	Shared Neighborhood Hits	16
SwissProt Accessions	Q6BEB4	Gene names	SP5
Domain Architecture	No domain graphic available
Description	Transcription factor Sp5.

SP5_MOUSE
θ value	6.88961 (rank : 71)	NC score	0.003598 (rank : 74)
Query Neighborhood Hits	78	Target Neighborhood Hits	821	Shared Neighborhood Hits	15
SwissProt Accessions	Q9JHX2	Gene names	Sp5
Domain Architecture
Description	Transcription factor Sp5.

CCD71_HUMAN
θ value	8.99809 (rank : 72)	NC score	0.014175 (rank : 52)
Query Neighborhood Hits	78	Target Neighborhood Hits	55	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IV32, Q6IPE2, Q9H8H4, Q9H9F1	Gene names	CCDC71
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 71.

CSPG2_MOUSE
θ value	8.99809 (rank : 73)	NC score	0.007656 (rank : 65)
Query Neighborhood Hits	78	Target Neighborhood Hits	711	Shared Neighborhood Hits	8
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

JHD2C_MOUSE
θ value	8.99809 (rank : 74)	NC score	0.007752 (rank : 64)
Query Neighborhood Hits	78	Target Neighborhood Hits	297	Shared Neighborhood Hits	6
SwissProt Accessions	Q69ZK6, Q6NV48, Q8BUF5, Q8C4I5, Q8C5Q9	Gene names	Jmjd1c, Jhdm2c, Kiaa1380
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C).

LHX3_HUMAN
θ value	8.99809 (rank : 75)	NC score	0.007632 (rank : 66)
Query Neighborhood Hits	78	Target Neighborhood Hits	474	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UBR4, Q9NZB5, Q9P0I8, Q9P0I9	Gene names	LHX3
Domain Architecture
Description	LIM/homeobox protein Lhx3.

LTBP2_MOUSE
θ value	8.99809 (rank : 76)	NC score	0.003854 (rank : 72)
Query Neighborhood Hits	78	Target Neighborhood Hits	617	Shared Neighborhood Hits	11
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

MAP2_HUMAN
θ value	8.99809 (rank : 77)	NC score	0.010039 (rank : 62)
Query Neighborhood Hits	78	Target Neighborhood Hits	348	Shared Neighborhood Hits	8
SwissProt Accessions	P11137, Q99975, Q99976	Gene names	MAP2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2) (MAP-2).

ZN509_MOUSE
θ value	8.99809 (rank : 78)	NC score	0.000697 (rank : 78)
Query Neighborhood Hits	78	Target Neighborhood Hits	990	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BXX2, Q8CID4, Q8K2Z6	Gene names	Znf509, Zfp509
Domain Architecture	No domain graphic available
Description	Zinc finger protein 509.

Hits sorted by NC score

SPHK2_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	78	Target Neighborhood Hits	78	Shared Neighborhood Hits	78
SwissProt Accessions	Q9JIA7, Q91VA9, Q9DBH6	Gene names	Sphk2
Domain Architecture
Description	Sphingosine kinase 2 (EC 2.7.1.-) (SK 2) (SPK 2).

SPHK2_HUMAN
NC score	0.978938 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	78	Target Neighborhood Hits	81	Shared Neighborhood Hits	25
SwissProt Accessions	Q9NRA0, Q9BRN1, Q9H0Q2, Q9NWU7	Gene names	SPHK2
Domain Architecture
Description	Sphingosine kinase 2 (EC 2.7.1.-) (SK 2) (SPK 2).

SPHK1_HUMAN
NC score	0.903254 (rank : 3)	θ value	1.01059e-59 (rank : 3)
Query Neighborhood Hits	78	Target Neighborhood Hits	15	Shared Neighborhood Hits	9
SwissProt Accessions	Q9NYA1, Q9HD92, Q9NY70, Q9NYL3	Gene names	SPHK1, SPHK, SPK
Domain Architecture
Description	Sphingosine kinase 1 (EC 2.7.1.-) (SK 1) (SPK 1).

CERK1_HUMAN
NC score	0.647346 (rank : 4)	θ value	3.17815e-21 (rank : 4)
Query Neighborhood Hits	78	Target Neighborhood Hits	10	Shared Neighborhood Hits	8
SwissProt Accessions	Q8TCT0, Q9BYB3, Q9UGE5	Gene names	CERK, KIAA1646
Domain Architecture
Description	Ceramide kinase (EC 2.7.1.138) (Acylsphingosine kinase) (hCERK) (Lipid kinase 4) (LK4).

CERK1_MOUSE
NC score	0.632921 (rank : 5)	θ value	1.13037e-18 (rank : 5)
Query Neighborhood Hits	78	Target Neighborhood Hits	17	Shared Neighborhood Hits	8
SwissProt Accessions	Q8K4Q7	Gene names	Cerk
Domain Architecture
Description	Ceramide kinase (EC 2.7.1.138) (Acylsphingosine kinase) (mCERK).

MULK_HUMAN
NC score	0.560344 (rank : 6)	θ value	3.52202e-12 (rank : 6)
Query Neighborhood Hits	78	Target Neighborhood Hits	13	Shared Neighborhood Hits	9
SwissProt Accessions	Q53H12, Q75KN1, Q96GC3, Q9NP48	Gene names	MULK, AGK
Domain Architecture	No domain graphic available
Description	Multiple substrate lipid kinase, mitochondrial precursor (EC 2.7.1.94) (EC 2.7.1.107) (Multi-substrate lipid kinase) (MuLK) (HsMuLK) (Acylglycerol kinase) (hAGK).

MULK_MOUSE
NC score	0.556524 (rank : 7)	θ value	1.02475e-11 (rank : 7)
Query Neighborhood Hits	78	Target Neighborhood Hits	10	Shared Neighborhood Hits	9
SwissProt Accessions	Q9ESW4, Q9D087	Gene names	Mulk
Domain Architecture	No domain graphic available
Description	Multiple substrate lipid kinase, mitochondrial precursor (EC 2.7.1.94) (EC 2.7.1.107) (Multi-substrate lipid kinase) (MuLK).

CERKL_HUMAN
NC score	0.450351 (rank : 8)	θ value	5.44631e-05 (rank : 8)
Query Neighborhood Hits	78	Target Neighborhood Hits	14	Shared Neighborhood Hits	8
SwissProt Accessions	Q49MI3, Q49MH9, Q49MI0, Q49MI1, Q49MI2, Q5DVJ2, Q5DVJ4, Q5DVJ5, Q6UZF6, Q6ZP59	Gene names	CERKL
Domain Architecture	No domain graphic available
Description	Ceramide kinase-like protein.

PRRT3_HUMAN
NC score	0.085803 (rank : 9)	θ value	0.00665767 (rank : 9)
Query Neighborhood Hits	78	Target Neighborhood Hits	998	Shared Neighborhood Hits	32
SwissProt Accessions	Q5FWE3, Q49AD0, Q6UXY6, Q8NBC9	Gene names	PRRT3, UNQ5823/PRO19642
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

CXX1_HUMAN
NC score	0.084537 (rank : 10)	θ value	0.47712 (rank : 19)
Query Neighborhood Hits	78	Target Neighborhood Hits	17	Shared Neighborhood Hits	4
SwissProt Accessions	O15255	Gene names	CXX1
Domain Architecture	No domain graphic available
Description	CAAX box protein 1 (Cerebral protein 5).

DGKI_HUMAN
NC score	0.073327 (rank : 11)	θ value	0.279714 (rank : 16)
Query Neighborhood Hits	78	Target Neighborhood Hits	609	Shared Neighborhood Hits	12
SwissProt Accessions	O75912, Q9NZ49	Gene names	DGKI
Domain Architecture
Description	Diacylglycerol kinase iota (EC 2.7.1.107) (Diglyceride kinase iota) (DGK-iota) (DAG kinase iota).

PRRT3_MOUSE
NC score	0.067677 (rank : 12)	θ value	2.36792 (rank : 39)
Query Neighborhood Hits	78	Target Neighborhood Hits	162	Shared Neighborhood Hits	8
SwissProt Accessions	Q6PE13	Gene names	Prrt3
Domain Architecture	No domain graphic available
Description	Proline-rich transmembrane protein 3.

ZN385_HUMAN
NC score	0.060763 (rank : 13)	θ value	0.125558 (rank : 12)
Query Neighborhood Hits	78	Target Neighborhood Hits	614	Shared Neighborhood Hits	22
SwissProt Accessions	Q96PM9, Q5VH53, Q9H7R6, Q9UFU3	Gene names	ZNF385, HZF, RZF
Domain Architecture
Description	Zinc finger protein 385 (Hematopoietic zinc finger protein) (Retinal zinc finger protein).

NRX2B_HUMAN
NC score	0.055468 (rank : 14)	θ value	0.21417 (rank : 14)
Query Neighborhood Hits	78	Target Neighborhood Hits	481	Shared Neighborhood Hits	19
SwissProt Accessions	P58401	Gene names	NRXN2
Domain Architecture	No domain graphic available
Description	Neurexin-2-beta precursor (Neurexin II-beta).

DGKA_HUMAN
NC score	0.054499 (rank : 15)	θ value	0.47712 (rank : 20)
Query Neighborhood Hits	78	Target Neighborhood Hits	151	Shared Neighborhood Hits	8
SwissProt Accessions	P23743, O75481, O75482, O75483	Gene names	DGKA, DAGK, DAGK1
Domain Architecture
Description	Diacylglycerol kinase alpha (EC 2.7.1.107) (Diglyceride kinase alpha) (DGK-alpha) (DAG kinase alpha) (80 kDa diacylglycerol kinase).

ABRA_HUMAN
NC score	0.053566 (rank : 16)	θ value	0.279714 (rank : 15)
Query Neighborhood Hits	78	Target Neighborhood Hits	52	Shared Neighborhood Hits	3
SwissProt Accessions	Q8N0Z2	Gene names	ABRA
Domain Architecture	No domain graphic available
Description	Actin-binding Rho-activating protein (Striated muscle activator of Rho-dependent signaling) (STARS).

DGKG_HUMAN
NC score	0.052384 (rank : 17)	θ value	1.38821 (rank : 27)
Query Neighborhood Hits	78	Target Neighborhood Hits	171	Shared Neighborhood Hits	8
SwissProt Accessions	P49619	Gene names	DGKG, DAGK3
Domain Architecture
Description	Diacylglycerol kinase gamma (EC 2.7.1.107) (Diglyceride kinase gamma) (DGK-gamma) (DAG kinase gamma).

RBM12_HUMAN
NC score	0.050426 (rank : 18)	θ value	0.62314 (rank : 21)
Query Neighborhood Hits	78	Target Neighborhood Hits	298	Shared Neighborhood Hits	16
SwissProt Accessions	Q9NTZ6, O94865, Q8N3B1, Q9H196	Gene names	RBM12, KIAA0765
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

DGKZ_MOUSE
NC score	0.049527 (rank : 19)	θ value	2.36792 (rank : 36)
Query Neighborhood Hits	78	Target Neighborhood Hits	542	Shared Neighborhood Hits	9
SwissProt Accessions	Q80UP3	Gene names	Dgkz
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

DGKZ_HUMAN
NC score	0.049116 (rank : 20)	θ value	2.36792 (rank : 35)
Query Neighborhood Hits	78	Target Neighborhood Hits	551	Shared Neighborhood Hits	9
SwissProt Accessions	Q13574, O00542	Gene names	DGKZ, DAGK6
Domain Architecture
Description	Diacylglycerol kinase zeta (EC 2.7.1.107) (Diglyceride kinase zeta) (DGK-zeta) (DAG kinase zeta).

SMR3A_HUMAN
NC score	0.048405 (rank : 21)	θ value	5.27518 (rank : 57)
Query Neighborhood Hits	78	Target Neighborhood Hits	93	Shared Neighborhood Hits	11
SwissProt Accessions	Q99954	Gene names	SMR3A, PBI, PROL5
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog A precursor (Proline-rich protein 5) (Proline-rich protein PBI).

DGKG_MOUSE
NC score	0.047926 (rank : 22)	θ value	4.03905 (rank : 47)
Query Neighborhood Hits	78	Target Neighborhood Hits	188	Shared Neighborhood Hits	8
SwissProt Accessions	Q91WG7	Gene names	Dgkg, Dagk3
Domain Architecture
Description	Diacylglycerol kinase gamma (EC 2.7.1.107) (Diglyceride kinase gamma) (DGK-gamma) (DAG kinase gamma) (88 kDa diacylglycerol kinase).

RBM12_MOUSE
NC score	0.046934 (rank : 23)	θ value	1.81305 (rank : 32)
Query Neighborhood Hits	78	Target Neighborhood Hits	313	Shared Neighborhood Hits	16
SwissProt Accessions	Q8R4X3, Q8K373, Q8R302, Q9CS80	Gene names	Rbm12
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

MEF2D_MOUSE
NC score	0.044910 (rank : 24)	θ value	0.365318 (rank : 18)
Query Neighborhood Hits	78	Target Neighborhood Hits	146	Shared Neighborhood Hits	9
SwissProt Accessions	Q63943, Q63944	Gene names	Mef2d
Domain Architecture
Description	Myocyte-specific enhancer factor 2D.

BCL9_MOUSE
NC score	0.044823 (rank : 25)	θ value	4.03905 (rank : 46)
Query Neighborhood Hits	78	Target Neighborhood Hits	770	Shared Neighborhood Hits	33
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

MEF2D_HUMAN
NC score	0.044702 (rank : 26)	θ value	0.365318 (rank : 17)
Query Neighborhood Hits	78	Target Neighborhood Hits	170	Shared Neighborhood Hits	9
SwissProt Accessions	Q14814, Q14815	Gene names	MEF2D
Domain Architecture
Description	Myocyte-specific enhancer factor 2D.

BCL9_HUMAN
NC score	0.044364 (rank : 27)	θ value	1.06291 (rank : 23)
Query Neighborhood Hits	78	Target Neighborhood Hits	1008	Shared Neighborhood Hits	36
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

SMAL1_MOUSE
NC score	0.044319 (rank : 28)	θ value	0.0961366 (rank : 10)
Query Neighborhood Hits	78	Target Neighborhood Hits	157	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BJL0, Q8BVK7, Q8BXW4, Q8K309, Q9EQK8, Q9QYC4	Gene names	Smarcal1, Harp
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (EC 3.6.1.-) (Sucrose nonfermenting protein 2-like 1) (HepA-related protein) (mharp).

SON_HUMAN
NC score	0.043827 (rank : 29)	θ value	0.125558 (rank : 11)
Query Neighborhood Hits	78	Target Neighborhood Hits	1568	Shared Neighborhood Hits	39
SwissProt Accessions	P18583, O14487, O95981, Q14120, Q9H7B1, Q9P070, Q9P072, Q9UKP9, Q9UPY0	Gene names	SON, C21orf50, DBP5, KIAA1019, NREBP
Domain Architecture
Description	SON protein (SON3) (Negative regulatory element-binding protein) (NRE- binding protein) (DBP-5) (Bax antagonist selected in saccharomyces 1) (BASS1).

YLPM1_MOUSE
NC score	0.043608 (rank : 30)	θ value	1.06291 (rank : 26)
Query Neighborhood Hits	78	Target Neighborhood Hits	505	Shared Neighborhood Hits	20
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

NRX2A_HUMAN
NC score	0.039557 (rank : 31)	θ value	0.21417 (rank : 13)
Query Neighborhood Hits	78	Target Neighborhood Hits	614	Shared Neighborhood Hits	20
SwissProt Accessions	Q9P2S2, Q9Y2D6	Gene names	NRXN2, KIAA0921
Domain Architecture
Description	Neurexin-2-alpha precursor (Neurexin II-alpha).

PI5PA_HUMAN
NC score	0.036748 (rank : 32)	θ value	2.36792 (rank : 38)
Query Neighborhood Hits	78	Target Neighborhood Hits	749	Shared Neighborhood Hits	37
SwissProt Accessions	Q15735, Q32M61, Q6ZTH6, Q8N902, Q9UDT9	Gene names	PIB5PA, PIPP
Domain Architecture
Description	Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A (EC 3.1.3.56).

RSMB_HUMAN
NC score	0.035547 (rank : 33)	θ value	5.27518 (rank : 55)
Query Neighborhood Hits	78	Target Neighborhood Hits	117	Shared Neighborhood Hits	17
SwissProt Accessions	P14678, Q15490, Q9UIS5	Gene names	SNRPB, COD, SNRPB1
Domain Architecture
Description	Small nuclear ribonucleoprotein-associated proteins B and B' (snRNP-B) (Sm protein B/B') (Sm-B/Sm-B') (SmB/SmB').

RSMB_MOUSE
NC score	0.033631 (rank : 34)	θ value	5.27518 (rank : 56)
Query Neighborhood Hits	78	Target Neighborhood Hits	93	Shared Neighborhood Hits	14
SwissProt Accessions	P27048, Q3UJT1	Gene names	Snrpb
Domain Architecture
Description	Small nuclear ribonucleoprotein-associated protein B (snRNP-B) (Sm protein B) (Sm-B) (SmB).

ATN1_HUMAN
NC score	0.031079 (rank : 35)	θ value	4.03905 (rank : 45)
Query Neighborhood Hits	78	Target Neighborhood Hits	676	Shared Neighborhood Hits	18
SwissProt Accessions	P54259, Q99495, Q99621, Q9UEK7	Gene names	ATN1, DRPLA
Domain Architecture
Description	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein).

NIBL_HUMAN
NC score	0.030556 (rank : 36)	θ value	1.38821 (rank : 28)
Query Neighborhood Hits	78	Target Neighborhood Hits	61	Shared Neighborhood Hits	4
SwissProt Accessions	Q96TA1, Q9BUS2, Q9NT35	Gene names	C9orf88
Domain Architecture	No domain graphic available
Description	Niban-like protein (Meg-3).

SF3B4_HUMAN
NC score	0.027093 (rank : 37)	θ value	0.62314 (rank : 22)
Query Neighborhood Hits	78	Target Neighborhood Hits	445	Shared Neighborhood Hits	17
SwissProt Accessions	Q15427	Gene names	SF3B4, SAP49
Domain Architecture
Description	Splicing factor 3B subunit 4 (Spliceosome-associated protein 49) (SAP 49) (SF3b50) (Pre-mRNA-splicing factor SF3b 49 kDa subunit).

SCAP_HUMAN
NC score	0.025309 (rank : 38)	θ value	1.06291 (rank : 25)
Query Neighborhood Hits	78	Target Neighborhood Hits	368	Shared Neighborhood Hits	8
SwissProt Accessions	Q12770, Q8N2E0, Q8WUA1	Gene names	SCAP, KIAA0199
Domain Architecture
Description	Sterol regulatory element-binding protein cleavage-activating protein (SREBP cleavage-activating protein) (SCAP).

FMNL_HUMAN
NC score	0.024719 (rank : 39)	θ value	5.27518 (rank : 52)
Query Neighborhood Hits	78	Target Neighborhood Hits	529	Shared Neighborhood Hits	20
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

CBP_MOUSE
NC score	0.023763 (rank : 40)	θ value	6.88961 (rank : 62)
Query Neighborhood Hits	78	Target Neighborhood Hits	1051	Shared Neighborhood Hits	31
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

LPP_HUMAN
NC score	0.021306 (rank : 41)	θ value	1.81305 (rank : 30)
Query Neighborhood Hits	78	Target Neighborhood Hits	775	Shared Neighborhood Hits	26
SwissProt Accessions	Q93052, Q8NFX5	Gene names	LPP
Domain Architecture	No domain graphic available
Description	Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma).

CSKI2_HUMAN
NC score	0.021053 (rank : 42)	θ value	1.06291 (rank : 24)
Query Neighborhood Hits	78	Target Neighborhood Hits	747	Shared Neighborhood Hits	23
SwissProt Accessions	Q8WXE0, Q7LG69, Q9ULT1	Gene names	CASKIN2, KIAA1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

PO121_MOUSE
NC score	0.019916 (rank : 43)	θ value	6.88961 (rank : 69)
Query Neighborhood Hits	78	Target Neighborhood Hits	345	Shared Neighborhood Hits	12
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

HSF4_MOUSE
NC score	0.019361 (rank : 44)	θ value	3.0926 (rank : 43)
Query Neighborhood Hits	78	Target Neighborhood Hits	57	Shared Neighborhood Hits	3
SwissProt Accessions	Q9R0L1, Q9R0L2	Gene names	Hsf4
Domain Architecture
Description	Heat shock factor protein 4 (HSF 4) (Heat shock transcription factor 4) (HSTF 4) (mHSF4).

PDZD2_HUMAN
NC score	0.019133 (rank : 45)	θ value	1.81305 (rank : 31)
Query Neighborhood Hits	78	Target Neighborhood Hits	772	Shared Neighborhood Hits	18
SwissProt Accessions	O15018, Q9BXD4	Gene names	PDZD2, AIPC, KIAA0300, PDZK3
Domain Architecture	No domain graphic available
Description	PDZ domain-containing protein 2 (PDZ domain-containing protein 3) (Activated in prostate cancer protein).

Z3H7A_HUMAN
NC score	0.018923 (rank : 46)	θ value	5.27518 (rank : 58)
Query Neighborhood Hits	78	Target Neighborhood Hits	105	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IWR0, Q9NPE9	Gene names	ZC3H7A, ZC3H7, ZC3HDC7
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH-type domain-containing protein 7A.

TAF3_HUMAN
NC score	0.017812 (rank : 47)	θ value	4.03905 (rank : 49)
Query Neighborhood Hits	78	Target Neighborhood Hits	568	Shared Neighborhood Hits	13
SwissProt Accessions	Q5VWG9, Q6GMS5, Q6P6B5, Q86VY6, Q9BQS9, Q9UFI8	Gene names	TAF3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

SAM68_HUMAN
NC score	0.017460 (rank : 48)	θ value	4.03905 (rank : 48)
Query Neighborhood Hits	78	Target Neighborhood Hits	68	Shared Neighborhood Hits	4
SwissProt Accessions	Q07666, Q6PJX7, Q8NB97, Q99760	Gene names	KHDRBS1, SAM68
Domain Architecture	No domain graphic available
Description	KH domain-containing, RNA-binding, signal transduction-associated protein 1 (p21 Ras GTPase-activating protein-associated p62) (GAP- associated tyrosine phosphoprotein p62) (Src-associated in mitosis 68 kDa protein) (Sam68) (p68).

MAML3_HUMAN
NC score	0.017127 (rank : 49)	θ value	6.88961 (rank : 65)
Query Neighborhood Hits	78	Target Neighborhood Hits	323	Shared Neighborhood Hits	10
SwissProt Accessions	Q96JK9	Gene names	MAML3, KIAA1816
Domain Architecture	No domain graphic available
Description	Mastermind-like protein 3 (Mam-3).

ACINU_HUMAN
NC score	0.017060 (rank : 50)	θ value	3.0926 (rank : 40)
Query Neighborhood Hits	78	Target Neighborhood Hits	828	Shared Neighborhood Hits	11
SwissProt Accessions	Q9UKV3, O75158, Q9UG91, Q9UKV1, Q9UKV2	Gene names	ACIN1, ACINUS, KIAA0670
Domain Architecture
Description	Apoptotic chromatin condensation inducer in the nucleus (Acinus).

CABL1_HUMAN
NC score	0.015348 (rank : 51)	θ value	5.27518 (rank : 51)
Query Neighborhood Hits	78	Target Neighborhood Hits	37	Shared Neighborhood Hits	2
SwissProt Accessions	Q8TDN4, Q8N3Y8, Q8NA22, Q9BTG1	Gene names	CABLES1, CABLES
Domain Architecture	No domain graphic available
Description	CDK5 and ABL1 enzyme substrate 1 (Interactor with CDK3 1) (Ik3-1).

CCD71_HUMAN
NC score	0.014175 (rank : 52)	θ value	8.99809 (rank : 72)
Query Neighborhood Hits	78	Target Neighborhood Hits	55	Shared Neighborhood Hits	2
SwissProt Accessions	Q8IV32, Q6IPE2, Q9H8H4, Q9H9F1	Gene names	CCDC71
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 71.

PGCA_MOUSE
NC score	0.014172 (rank : 53)	θ value	6.88961 (rank : 68)
Query Neighborhood Hits	78	Target Neighborhood Hits	643	Shared Neighborhood Hits	12
SwissProt Accessions	Q61282, Q64021	Gene names	Agc1, Agc
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP).

PRAM6_HUMAN
NC score	0.013557 (rank : 54)	θ value	5.27518 (rank : 54)
Query Neighborhood Hits	78	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	Q5VXH4	Gene names	PRAMEF6
Domain Architecture	No domain graphic available
Description	PRAME family member 6.

PRAM5_HUMAN
NC score	0.013552 (rank : 55)	θ value	5.27518 (rank : 53)
Query Neighborhood Hits	78	Target Neighborhood Hits	31	Shared Neighborhood Hits	3
SwissProt Accessions	Q5TYX0	Gene names	PRAMEF5
Domain Architecture	No domain graphic available
Description	PRAME family member 5.

CAC1B_MOUSE
NC score	0.012850 (rank : 56)	θ value	3.0926 (rank : 42)
Query Neighborhood Hits	78	Target Neighborhood Hits	351	Shared Neighborhood Hits	10
SwissProt Accessions	O55017, Q60609	Gene names	Cacna1b, Cach5, Cacnl1a5, Cchn1a
Domain Architecture
Description	Voltage-dependent N-type calcium channel subunit alpha-1B (Voltage- gated calcium channel subunit alpha Cav2.2) (Calcium channel, L type, alpha-1 polypeptide isoform 5) (Brain calcium channel III) (BIII).

PGCA_HUMAN
NC score	0.012829 (rank : 57)	θ value	6.88961 (rank : 67)
Query Neighborhood Hits	78	Target Neighborhood Hits	821	Shared Neighborhood Hits	17
SwissProt Accessions	P16112, Q13650, Q9UCP4, Q9UCP5, Q9UDE0	Gene names	AGC1, CSPG1
Domain Architecture
Description	Aggrecan core protein precursor (Cartilage-specific proteoglycan core protein) (CSPCP) (Chondroitin sulfate proteoglycan core protein 1) [Contains: Aggrecan core protein 2].

CAC1G_HUMAN
NC score	0.012581 (rank : 58)	θ value	6.88961 (rank : 61)
Query Neighborhood Hits	78	Target Neighborhood Hits	587	Shared Neighborhood Hits	21
SwissProt Accessions	O43497, O43498, O94770, Q9NYU4, Q9NYU5, Q9NYU6, Q9NYU7, Q9NYU8, Q9NYU9, Q9NYV0, Q9NYV1, Q9UHN9, Q9UHP0, Q9ULU6, Q9UNG7, Q9Y5T2, Q9Y5T3	Gene names	CACNA1G, KIAA1123
Domain Architecture
Description	Voltage-dependent T-type calcium channel subunit alpha-1G (Voltage- gated calcium channel subunit alpha Cav3.1) (Cav3.1c) (NBR13).

ATOH1_MOUSE
NC score	0.010571 (rank : 59)	θ value	6.88961 (rank : 60)
Query Neighborhood Hits	78	Target Neighborhood Hits	100	Shared Neighborhood Hits	2
SwissProt Accessions	P48985	Gene names	Atoh1, Ath1
Domain Architecture
Description	Atonal protein homolog 1 (Helix-loop-helix protein mATH-1) (MATH1).

PLXB1_MOUSE
NC score	0.010530 (rank : 60)	θ value	3.0926 (rank : 44)
Query Neighborhood Hits	78	Target Neighborhood Hits	259	Shared Neighborhood Hits	6
SwissProt Accessions	Q8CJH3, Q6ZQC3, Q80ZZ1	Gene names	Plxnb1, Kiaa0407
Domain Architecture	No domain graphic available
Description	Plexin-B1 precursor.

ATBF1_MOUSE
NC score	0.010395 (rank : 61)	θ value	5.27518 (rank : 50)
Query Neighborhood Hits	78	Target Neighborhood Hits	1841	Shared Neighborhood Hits	29
SwissProt Accessions	Q61329	Gene names	Atbf1
Domain Architecture
Description	Alpha-fetoprotein enhancer-binding protein (AT motif-binding factor) (AT-binding transcription factor 1).

MAP2_HUMAN
NC score	0.010039 (rank : 62)	θ value	8.99809 (rank : 77)
Query Neighborhood Hits	78	Target Neighborhood Hits	348	Shared Neighborhood Hits	8
SwissProt Accessions	P11137, Q99975, Q99976	Gene names	MAP2
Domain Architecture
Description	Microtubule-associated protein 2 (MAP 2) (MAP-2).

ZBTB3_HUMAN
NC score	0.009685 (rank : 63)	θ value	1.81305 (rank : 34)
Query Neighborhood Hits	78	Target Neighborhood Hits	910	Shared Neighborhood Hits	14
SwissProt Accessions	Q9H5J0	Gene names	ZBTB3
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 3.

JHD2C_MOUSE
NC score	0.007752 (rank : 64)	θ value	8.99809 (rank : 74)
Query Neighborhood Hits	78	Target Neighborhood Hits	297	Shared Neighborhood Hits	6
SwissProt Accessions	Q69ZK6, Q6NV48, Q8BUF5, Q8C4I5, Q8C5Q9	Gene names	Jmjd1c, Jhdm2c, Kiaa1380
Domain Architecture	No domain graphic available
Description	Probable JmjC domain-containing histone demethylation protein 2C (EC 1.14.11.-) (Jumonji domain-containing protein 1C).

CSPG2_MOUSE
NC score	0.007656 (rank : 65)	θ value	8.99809 (rank : 73)
Query Neighborhood Hits	78	Target Neighborhood Hits	711	Shared Neighborhood Hits	8
SwissProt Accessions	Q62059, Q62058, Q9CUU0	Gene names	Cspg2
Domain Architecture
Description	Versican core protein precursor (Large fibroblast proteoglycan) (Chondroitin sulfate proteoglycan core protein 2) (PG-M).

LHX3_HUMAN
NC score	0.007632 (rank : 66)	θ value	8.99809 (rank : 75)
Query Neighborhood Hits	78	Target Neighborhood Hits	474	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UBR4, Q9NZB5, Q9P0I8, Q9P0I9	Gene names	LHX3
Domain Architecture
Description	LIM/homeobox protein Lhx3.

ZN687_HUMAN
NC score	0.007462 (rank : 67)	θ value	5.27518 (rank : 59)
Query Neighborhood Hits	78	Target Neighborhood Hits	1244	Shared Neighborhood Hits	27
SwissProt Accessions	Q8N1G0, Q68DQ8, Q9H937, Q9P2A7	Gene names	ZNF687, KIAA1441
Domain Architecture	No domain graphic available
Description	Zinc finger protein 687.

FBLN2_MOUSE
NC score	0.006585 (rank : 68)	θ value	6.88961 (rank : 63)
Query Neighborhood Hits	78	Target Neighborhood Hits	505	Shared Neighborhood Hits	14
SwissProt Accessions	P37889, Q9WUI2	Gene names	Fbln2
Domain Architecture
Description	Fibulin-2 precursor.

FOXK1_MOUSE
NC score	0.006472 (rank : 69)	θ value	6.88961 (rank : 64)
Query Neighborhood Hits	78	Target Neighborhood Hits	215	Shared Neighborhood Hits	8
SwissProt Accessions	P42128, O35939	Gene names	Foxk1, Mnf
Domain Architecture
Description	Forkhead box protein K1 (Myocyte nuclear factor) (MNF).

SPEG_HUMAN
NC score	0.006338 (rank : 70)	θ value	1.81305 (rank : 33)
Query Neighborhood Hits	78	Target Neighborhood Hits	1762	Shared Neighborhood Hits	27
SwissProt Accessions	Q15772, Q27J74, Q695L1, Q6FGA6, Q6ZQW1, Q6ZTL8, Q9P2P9	Gene names	SPEG, APEG1, KIAA1297
Domain Architecture
Description	Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1).

EPHB6_HUMAN
NC score	0.004220 (rank : 71)	θ value	1.81305 (rank : 29)
Query Neighborhood Hits	78	Target Neighborhood Hits	912	Shared Neighborhood Hits	9
SwissProt Accessions	O15197	Gene names	EPHB6
Domain Architecture
Description	Ephrin type-B receptor 6 precursor (Tyrosine-protein kinase-defective receptor EPH-6) (HEP).

LTBP2_MOUSE
NC score	0.003854 (rank : 72)	θ value	8.99809 (rank : 76)
Query Neighborhood Hits	78	Target Neighborhood Hits	617	Shared Neighborhood Hits	11
SwissProt Accessions	O08999, Q8C6W9	Gene names	Ltbp2
Domain Architecture
Description	Latent-transforming growth factor beta-binding protein 2 precursor (LTBP-2).

SP5_HUMAN
NC score	0.003800 (rank : 73)	θ value	6.88961 (rank : 70)
Query Neighborhood Hits	78	Target Neighborhood Hits	832	Shared Neighborhood Hits	16
SwissProt Accessions	Q6BEB4	Gene names	SP5
Domain Architecture	No domain graphic available
Description	Transcription factor Sp5.

SP5_MOUSE
NC score	0.003598 (rank : 74)	θ value	6.88961 (rank : 71)
Query Neighborhood Hits	78	Target Neighborhood Hits	821	Shared Neighborhood Hits	15
SwissProt Accessions	Q9JHX2	Gene names	Sp5
Domain Architecture
Description	Transcription factor Sp5.

HIC1_HUMAN
NC score	0.003355 (rank : 75)	θ value	2.36792 (rank : 37)
Query Neighborhood Hits	78	Target Neighborhood Hits	838	Shared Neighborhood Hits	12
SwissProt Accessions	Q14526	Gene names	HIC1, ZBTB29
Domain Architecture
Description	Hypermethylated in cancer 1 protein (Hic-1) (Zinc finger and BTB domain-containing protein 29).

MK07_HUMAN
NC score	0.003060 (rank : 76)	θ value	6.88961 (rank : 66)
Query Neighborhood Hits	78	Target Neighborhood Hits	1087	Shared Neighborhood Hits	17
SwissProt Accessions	Q13164, Q16634	Gene names	MAPK7, ERK4, ERK5, PRKM7
Domain Architecture
Description	Mitogen-activated protein kinase 7 (EC 2.7.11.24) (Extracellular signal-regulated kinase 5) (ERK-5) (ERK4) (BMK1 kinase).

BRSK1_HUMAN
NC score	0.002252 (rank : 77)	θ value	3.0926 (rank : 41)
Query Neighborhood Hits	78	Target Neighborhood Hits	942	Shared Neighborhood Hits	11
SwissProt Accessions	Q8TDC3, Q5J5B5, Q8NDD0, Q8NDR4, Q8TDC2, Q96AV4, Q96JL4	Gene names	BRSK1, KIAA1811, SAD1
Domain Architecture
Description	BR serine/threonine-protein kinase 1 (EC 2.7.11.1) (SAD1 kinase) (SAD1A).

ZN509_MOUSE
NC score	0.000697 (rank : 78)	θ value	8.99809 (rank : 78)
Query Neighborhood Hits	78	Target Neighborhood Hits	990	Shared Neighborhood Hits	11
SwissProt Accessions	Q8BXX2, Q8CID4, Q8K2Z6	Gene names	Znf509, Zfp509
Domain Architecture	No domain graphic available
Description	Zinc finger protein 509.