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Network neighborhood for query Sequence : RXRA_HUMAN

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RXRA_HUMAN
SwissProt Accessions	P19793, Q2V504	Gene names	RXRA, NR2B1
Domain Architecture
Description	Retinoic acid receptor RXR-alpha (Retinoid X receptor alpha).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

RXRA_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	223	Target Neighborhood Hits	223	Shared Neighborhood Hits	223
SwissProt Accessions	P19793, Q2V504	Gene names	RXRA, NR2B1
Domain Architecture
Description	Retinoic acid receptor RXR-alpha (Retinoid X receptor alpha).

RXRA_MOUSE
θ value	0 (rank : 2)	NC score	0.997263 (rank : 2)
Query Neighborhood Hits	223	Target Neighborhood Hits	129	Shared Neighborhood Hits	122
SwissProt Accessions	P28700	Gene names	Rxra, Nr2b1
Domain Architecture
Description	Retinoic acid receptor RXR-alpha (Retinoid X receptor alpha).

RXRG_MOUSE
θ value	2.17943e-171 (rank : 3)	NC score	0.993745 (rank : 3)
Query Neighborhood Hits	223	Target Neighborhood Hits	113	Shared Neighborhood Hits	98
SwissProt Accessions	P28705	Gene names	Rxrg, Nr2b3
Domain Architecture
Description	Retinoic acid receptor RXR-gamma (Retinoid X receptor gamma).

RXRG_HUMAN
θ value	6.34118e-171 (rank : 4)	NC score	0.993744 (rank : 4)
Query Neighborhood Hits	223	Target Neighborhood Hits	114	Shared Neighborhood Hits	99
SwissProt Accessions	P48443	Gene names	RXRG, NR2B3
Domain Architecture
Description	Retinoic acid receptor RXR-gamma (Retinoid X receptor gamma).

RXRB_HUMAN
θ value	3.25673e-167 (rank : 5)	NC score	0.985407 (rank : 6)
Query Neighborhood Hits	223	Target Neighborhood Hits	280	Shared Neighborhood Hits	109
SwissProt Accessions	P28702, P28703	Gene names	RXRB, NR2B2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta).

RXRB_MOUSE
θ value	3.37019e-164 (rank : 6)	NC score	0.989598 (rank : 5)
Query Neighborhood Hits	223	Target Neighborhood Hits	230	Shared Neighborhood Hits	112
SwissProt Accessions	P28704, P33243	Gene names	Rxrb, Nr2b2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta) (MHC class I regulatory element-binding protein H-2RIIBP).

COT1_HUMAN
θ value	1.45253e-74 (rank : 7)	NC score	0.975643 (rank : 16)
Query Neighborhood Hits	223	Target Neighborhood Hits	159	Shared Neighborhood Hits	100
SwissProt Accessions	P10589	Gene names	NR2F1, EAR3, ERBAL3, TFCOUP1
Domain Architecture
Description	COUP transcription factor 1 (COUP-TF1) (COUP-TF I) (V-ERBA-related protein EAR-3).

COT1_MOUSE
θ value	1.45253e-74 (rank : 8)	NC score	0.975961 (rank : 15)
Query Neighborhood Hits	223	Target Neighborhood Hits	160	Shared Neighborhood Hits	100
SwissProt Accessions	Q60632, Q61438	Gene names	Nr2f1, Erbal3, Tfcoup1
Domain Architecture
Description	COUP transcription factor 1 (COUP-TF1) (COUP-TF I).

COT2_HUMAN
θ value	3.23591e-74 (rank : 9)	NC score	0.977225 (rank : 11)
Query Neighborhood Hits	223	Target Neighborhood Hits	135	Shared Neighborhood Hits	101
SwissProt Accessions	P24468, Q03754	Gene names	NR2F2, ARP1, TFCOUP2
Domain Architecture
Description	COUP transcription factor 2 (COUP-TF2) (COUP-TF II) (Apolipoprotein AI regulatory protein 1) (ARP-1).

COT2_MOUSE
θ value	3.23591e-74 (rank : 10)	NC score	0.977225 (rank : 12)
Query Neighborhood Hits	223	Target Neighborhood Hits	135	Shared Neighborhood Hits	101
SwissProt Accessions	P43135	Gene names	Nr2f2, Aporp1, Arp-1, Arp1, Tfcoup2
Domain Architecture
Description	COUP transcription factor 2 (COUP-TF2) (COUP-TF II) (Apolipoprotein AI regulatory protein 1) (ARP-1).

HNF4A_HUMAN
θ value	5.91091e-68 (rank : 11)	NC score	0.978176 (rank : 10)
Query Neighborhood Hits	223	Target Neighborhood Hits	105	Shared Neighborhood Hits	98
SwissProt Accessions	P41235, O00659, O00723, Q14540, Q92653, Q92654, Q92655, Q99864, Q9NQH0	Gene names	HNF4A, HNF4, NR2A1, TCF14
Domain Architecture
Description	Hepatocyte nuclear factor 4-alpha (HNF-4-alpha) (Transcription factor HNF-4) (Transcription factor 14).

HNF4G_MOUSE
θ value	5.91091e-68 (rank : 12)	NC score	0.978642 (rank : 8)
Query Neighborhood Hits	223	Target Neighborhood Hits	101	Shared Neighborhood Hits	98
SwissProt Accessions	Q9WUU6	Gene names	Hnf4g, Nr2a2
Domain Architecture
Description	Hepatocyte nuclear factor 4-gamma (HNF-4-gamma).

HNF4G_HUMAN
θ value	7.71989e-68 (rank : 13)	NC score	0.978957 (rank : 7)
Query Neighborhood Hits	223	Target Neighborhood Hits	100	Shared Neighborhood Hits	98
SwissProt Accessions	Q14541, Q9UH81, Q9UIS6	Gene names	HNF4G, NR2A2
Domain Architecture
Description	Hepatocyte nuclear factor 4-gamma (HNF-4-gamma).

HNF4A_MOUSE
θ value	2.93355e-67 (rank : 14)	NC score	0.978483 (rank : 9)
Query Neighborhood Hits	223	Target Neighborhood Hits	103	Shared Neighborhood Hits	98
SwissProt Accessions	P49698	Gene names	Hnf4a, Hnf-4, Hnf4, Nr2a1, Tcf14
Domain Architecture
Description	Hepatocyte nuclear factor 4-alpha (HNF-4-alpha) (Transcription factor HNF-4) (Transcription factor 14).

EAR2_HUMAN
θ value	1.77973e-64 (rank : 15)	NC score	0.977169 (rank : 13)
Query Neighborhood Hits	223	Target Neighborhood Hits	106	Shared Neighborhood Hits	98
SwissProt Accessions	P10588, Q9BUE8	Gene names	NR2F6, EAR2, ERBAL2
Domain Architecture
Description	Orphan nuclear receptor EAR-2 (V-erbA-related protein EAR-2).

EAR2_MOUSE
θ value	4.38363e-63 (rank : 16)	NC score	0.976331 (rank : 14)
Query Neighborhood Hits	223	Target Neighborhood Hits	104	Shared Neighborhood Hits	98
SwissProt Accessions	P43136, Q61504	Gene names	Nr2f6, Ear-2, Ear2, Erbal2
Domain Architecture
Description	Orphan nuclear receptor EAR-2 (V-erbA-related protein EAR-2).

ERR3_HUMAN
θ value	1.36585e-56 (rank : 17)	NC score	0.961832 (rank : 21)
Query Neighborhood Hits	223	Target Neighborhood Hits	106	Shared Neighborhood Hits	98
SwissProt Accessions	P62508, O75454, O96021, Q68DA0, Q6P274, Q6PK28, Q6TS38, Q9R1F3, Q9UNJ4	Gene names	ESRRG, ERR3, ERRG2, KIAA0832, NR3B3
Domain Architecture	No domain graphic available
Description	Estrogen-related receptor gamma (Estrogen receptor-related protein 3) (ERR gamma-2).

ERR3_MOUSE
θ value	1.36585e-56 (rank : 18)	NC score	0.961832 (rank : 22)
Query Neighborhood Hits	223	Target Neighborhood Hits	106	Shared Neighborhood Hits	98
SwissProt Accessions	P62509, O75454, O96021, Q8CHC9, Q9R1F3	Gene names	Esrrg, Err3, Kiaa0832, Nr3b3
Domain Architecture	No domain graphic available
Description	Estrogen-related receptor gamma (Estrogen receptor-related protein 3).

NR2E3_HUMAN
θ value	3.0428e-56 (rank : 19)	NC score	0.974423 (rank : 17)
Query Neighborhood Hits	223	Target Neighborhood Hits	102	Shared Neighborhood Hits	99
SwissProt Accessions	Q9Y5X4, Q9UHM4	Gene names	NR2E3, PNR, RNR
Domain Architecture
Description	Photoreceptor-specific nuclear receptor (Retina-specific nuclear receptor).

ERR2_MOUSE
θ value	6.34462e-54 (rank : 20)	NC score	0.960913 (rank : 23)
Query Neighborhood Hits	223	Target Neighborhood Hits	109	Shared Neighborhood Hits	99
SwissProt Accessions	Q61539, O09067, O09146	Gene names	Esrrb, Err-2, Err2, Nr3b2
Domain Architecture
Description	Steroid hormone receptor ERR2 (Estrogen-related receptor, beta) (ERR- beta) (Estrogen receptor-like 2).

NR2E3_MOUSE
θ value	2.41096e-53 (rank : 21)	NC score	0.973109 (rank : 18)
Query Neighborhood Hits	223	Target Neighborhood Hits	113	Shared Neighborhood Hits	98
SwissProt Accessions	Q9QXZ7	Gene names	Nr2e3, Pnr, Rnr
Domain Architecture
Description	Photoreceptor-specific nuclear receptor (Retina-specific nuclear receptor).

RARB_HUMAN
θ value	2.66562e-52 (rank : 22)	NC score	0.948331 (rank : 26)
Query Neighborhood Hits	223	Target Neighborhood Hits	118	Shared Neighborhood Hits	94
SwissProt Accessions	P10826, P12891, Q00989, Q15298, Q9UN48	Gene names	RARB, HAP, NR1B2
Domain Architecture
Description	Retinoic acid receptor beta (RAR-beta) (RAR-epsilon) (HBV-activated protein).

RARB_MOUSE
θ value	2.66562e-52 (rank : 23)	NC score	0.948245 (rank : 27)
Query Neighborhood Hits	223	Target Neighborhood Hits	109	Shared Neighborhood Hits	95
SwissProt Accessions	P22605, P11417, P22604	Gene names	Rarb, Nr1b2
Domain Architecture
Description	Retinoic acid receptor beta (RAR-beta).

ERR2_HUMAN
θ value	1.01294e-51 (rank : 24)	NC score	0.958519 (rank : 24)
Query Neighborhood Hits	223	Target Neighborhood Hits	108	Shared Neighborhood Hits	99
SwissProt Accessions	O95718, Q9HCB4	Gene names	ESRRB, ERRB2, NR3B2
Domain Architecture
Description	Steroid hormone receptor ERR2 (Estrogen-related receptor, beta) (ERR- beta) (Estrogen receptor-like 2) (ERR beta-2).

NR2E1_MOUSE
θ value	2.94719e-51 (rank : 25)	NC score	0.971260 (rank : 19)
Query Neighborhood Hits	223	Target Neighborhood Hits	106	Shared Neighborhood Hits	100
SwissProt Accessions	Q64104	Gene names	Nr2e1, Tll, Tlx
Domain Architecture
Description	Orphan nuclear receptor NR2E1 (Nuclear receptor TLX) (Tailless homolog) (Tll) (mTll).

NR2E1_HUMAN
θ value	1.91031e-50 (rank : 26)	NC score	0.969233 (rank : 20)
Query Neighborhood Hits	223	Target Neighborhood Hits	103	Shared Neighborhood Hits	98
SwissProt Accessions	Q9Y466	Gene names	NR2E1, TLX
Domain Architecture
Description	Orphan nuclear receptor NR2E1 (Nuclear receptor TLX) (Tailless homolog) (Tll) (hTll).

RARA_HUMAN
θ value	1.23823e-49 (rank : 27)	NC score	0.947893 (rank : 29)
Query Neighborhood Hits	223	Target Neighborhood Hits	118	Shared Neighborhood Hits	96
SwissProt Accessions	P10276, P78456, Q13440, Q13441, Q9NQS0	Gene names	RARA, NR1B1
Domain Architecture
Description	Retinoic acid receptor alpha (RAR-alpha).

RARA_MOUSE
θ value	1.23823e-49 (rank : 28)	NC score	0.948026 (rank : 28)
Query Neighborhood Hits	223	Target Neighborhood Hits	113	Shared Neighborhood Hits	96
SwissProt Accessions	P11416, P22603	Gene names	Rara, Nr1b1
Domain Architecture
Description	Retinoic acid receptor alpha (RAR-alpha).

RARG1_MOUSE
θ value	2.1121e-49 (rank : 29)	NC score	0.946718 (rank : 33)
Query Neighborhood Hits	223	Target Neighborhood Hits	113	Shared Neighborhood Hits	96
SwissProt Accessions	P18911, Q91VK5	Gene names	Rarg, Nr1b3
Domain Architecture
Description	Retinoic acid receptor gamma-A (RAR-gamma-A).

RARG2_MOUSE
θ value	2.1121e-49 (rank : 30)	NC score	0.947017 (rank : 31)
Query Neighborhood Hits	223	Target Neighborhood Hits	114	Shared Neighborhood Hits	96
SwissProt Accessions	P20787	Gene names	Rarg, Nr1b3
Domain Architecture
Description	Retinoic acid receptor gamma-B (RAR-gamma-B).

RARG1_HUMAN
θ value	1.36902e-48 (rank : 31)	NC score	0.947008 (rank : 32)
Query Neighborhood Hits	223	Target Neighborhood Hits	107	Shared Neighborhood Hits	95
SwissProt Accessions	P13631	Gene names	RARG, NR1B3
Domain Architecture
Description	Retinoic acid receptor gamma-1 (RAR-gamma-1).

RARG2_HUMAN
θ value	1.36902e-48 (rank : 32)	NC score	0.947163 (rank : 30)
Query Neighborhood Hits	223	Target Neighborhood Hits	109	Shared Neighborhood Hits	95
SwissProt Accessions	P22932, Q15281	Gene names	RARG, NR1B3
Domain Architecture	No domain graphic available
Description	Retinoic acid receptor gamma-2 (RAR-gamma-2).

NR4A2_HUMAN
θ value	1.41672e-45 (rank : 33)	NC score	0.944823 (rank : 35)
Query Neighborhood Hits	223	Target Neighborhood Hits	120	Shared Neighborhood Hits	96
SwissProt Accessions	P43354, Q16311	Gene names	NR4A2, NOT, NURR1, TINUR
Domain Architecture
Description	Orphan nuclear receptor NR4A2 (Orphan nuclear receptor NURR1) (Immediate-early response protein NOT) (Transcriptionally-inducible nuclear receptor).

NR4A2_MOUSE
θ value	1.41672e-45 (rank : 34)	NC score	0.944865 (rank : 34)
Query Neighborhood Hits	223	Target Neighborhood Hits	121	Shared Neighborhood Hits	96
SwissProt Accessions	Q06219, O08690	Gene names	Nr4a2, Nurr1
Domain Architecture
Description	Orphan nuclear receptor NR4A2 (Orphan nuclear receptor NURR1) (NUR- related factor 1).

ERR1_HUMAN
θ value	1.19932e-44 (rank : 35)	NC score	0.956389 (rank : 25)
Query Neighborhood Hits	223	Target Neighborhood Hits	157	Shared Neighborhood Hits	104
SwissProt Accessions	P11474, Q14514	Gene names	ESRRA, ERR1, ESRL1, NR3B1
Domain Architecture
Description	Steroid hormone receptor ERR1 (Estrogen-related receptor, alpha) (ERR- alpha) (Estrogen receptor-like 1).

NR4A3_MOUSE
θ value	6.15952e-41 (rank : 36)	NC score	0.943911 (rank : 36)
Query Neighborhood Hits	223	Target Neighborhood Hits	127	Shared Neighborhood Hits	95
SwissProt Accessions	Q9QZB6, Q9QZB5	Gene names	Nr4a3, Tec
Domain Architecture
Description	Orphan nuclear receptor NR4A3 (Orphan nuclear receptor TEC) (Translocated in extraskeletal chondrosarcoma).

NR4A3_HUMAN
θ value	8.89434e-40 (rank : 37)	NC score	0.943056 (rank : 37)
Query Neighborhood Hits	223	Target Neighborhood Hits	131	Shared Neighborhood Hits	95
SwissProt Accessions	Q92570, Q12935, Q14979, Q16420, Q4VXA9, Q9UEK2, Q9UEK3	Gene names	NR4A3, CHN, CSMF, MINOR, NOR1, TEC
Domain Architecture
Description	Orphan nuclear receptor NR4A3 (Nuclear hormone receptor NOR-1) (Neuron-derived orphan receptor 1) (Mitogen-induced nuclear orphan receptor).

ESR2_MOUSE
θ value	1.98146e-39 (rank : 38)	NC score	0.939405 (rank : 41)
Query Neighborhood Hits	223	Target Neighborhood Hits	110	Shared Neighborhood Hits	96
SwissProt Accessions	O08537, O35635, O70519	Gene names	Esr2, Estrb, Nr3a2
Domain Architecture
Description	Estrogen receptor beta (ER-beta).

ESR2_HUMAN
θ value	4.41421e-39 (rank : 39)	NC score	0.941071 (rank : 39)
Query Neighborhood Hits	223	Target Neighborhood Hits	110	Shared Neighborhood Hits	98
SwissProt Accessions	Q92731, O60608, O60685, O60702, O60703, O75583, O75584, Q86Z31, Q9UEV6, Q9UHD3, Q9UQK9	Gene names	ESR2, ESTRB, NR3A2
Domain Architecture
Description	Estrogen receptor beta (ER-beta).

THA_HUMAN
θ value	3.73686e-38 (rank : 40)	NC score	0.927946 (rank : 52)
Query Neighborhood Hits	223	Target Neighborhood Hits	113	Shared Neighborhood Hits	97
SwissProt Accessions	P10827, P21205, Q8N6A1, Q96H73	Gene names	THRA, ERBA1, NR1A1, THRA1
Domain Architecture
Description	Thyroid hormone receptor alpha (C-erbA-alpha) (c-erbA-1) (EAR-7) (EAR7).

THA_MOUSE
θ value	3.73686e-38 (rank : 41)	NC score	0.927919 (rank : 53)
Query Neighborhood Hits	223	Target Neighborhood Hits	113	Shared Neighborhood Hits	97
SwissProt Accessions	P63058, P10685, P15827, P16416, P37241, Q63107, Q63195, Q63196, Q99146	Gene names	Thra, C-erba-alpha, Nr1a1
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor alpha (C-erbA-alpha) (c-erbA-1).

NR4A1_HUMAN
θ value	2.05049e-36 (rank : 42)	NC score	0.941729 (rank : 38)
Query Neighborhood Hits	223	Target Neighborhood Hits	133	Shared Neighborhood Hits	98
SwissProt Accessions	P22736	Gene names	NR4A1, GFRP1, HMR, NAK1
Domain Architecture
Description	Orphan nuclear receptor NR4A1 (Orphan nuclear receptor HMR) (Early response protein NAK1) (TR3 orphan receptor) (ST-59).

PPARD_MOUSE
θ value	2.67802e-36 (rank : 43)	NC score	0.921085 (rank : 66)
Query Neighborhood Hits	223	Target Neighborhood Hits	103	Shared Neighborhood Hits	94
SwissProt Accessions	P35396, P37239	Gene names	Ppard, Nr1c2, Pparb
Domain Architecture
Description	Peroxisome proliferator-activated receptor delta (PPAR-delta) (PPAR- beta) (Nuclear hormone receptor 1) (NUC1).

PPARD_HUMAN
θ value	3.4976e-36 (rank : 44)	NC score	0.922839 (rank : 61)
Query Neighborhood Hits	223	Target Neighborhood Hits	102	Shared Neighborhood Hits	94
SwissProt Accessions	Q03181, Q7Z5K0, Q9BUD4	Gene names	PPARD, NR1C2, PPARB
Domain Architecture
Description	Peroxisome proliferator-activated receptor delta (PPAR-delta) (PPAR- beta) (Nuclear hormone receptor 1) (NUC1) (NUCI).

PPARA_HUMAN
θ value	5.96599e-36 (rank : 45)	NC score	0.926568 (rank : 56)
Query Neighborhood Hits	223	Target Neighborhood Hits	100	Shared Neighborhood Hits	94
SwissProt Accessions	Q07869, Q16241, Q92486, Q92689, Q9Y3N1	Gene names	PPARA, NR1C1, PPAR
Domain Architecture
Description	Peroxisome proliferator-activated receptor alpha (PPAR-alpha).

NR4A1_MOUSE
θ value	1.01765e-35 (rank : 46)	NC score	0.940157 (rank : 40)
Query Neighborhood Hits	223	Target Neighborhood Hits	128	Shared Neighborhood Hits	98
SwissProt Accessions	P12813	Gene names	Nr4a1, Gfrp, Hmr, N10, Nur77
Domain Architecture
Description	Orphan nuclear receptor NR4A1 (Orphan nuclear receptor HMR) (Nuclear hormone receptor NUR/77) (N10 nuclear protein).

ESR1_HUMAN
θ value	1.46948e-34 (rank : 47)	NC score	0.934789 (rank : 43)
Query Neighborhood Hits	223	Target Neighborhood Hits	105	Shared Neighborhood Hits	95
SwissProt Accessions	P03372, Q13511, Q14276, Q9NU51, Q9UDZ7, Q9UIS7	Gene names	ESR1, ESR, NR3A1
Domain Architecture
Description	Estrogen receptor (ER) (Estradiol receptor) (ER-alpha).

ESR1_MOUSE
θ value	5.584e-34 (rank : 48)	NC score	0.934831 (rank : 42)
Query Neighborhood Hits	223	Target Neighborhood Hits	104	Shared Neighborhood Hits	95
SwissProt Accessions	P19785, Q9JJT5, Q9QY51, Q9QY52	Gene names	Esr1, Esr, Estr, Estra, Nr3a1
Domain Architecture
Description	Estrogen receptor (ER) (Estradiol receptor) (ER-alpha).

THB1_HUMAN
θ value	1.6247e-33 (rank : 49)	NC score	0.921651 (rank : 65)
Query Neighborhood Hits	223	Target Neighborhood Hits	106	Shared Neighborhood Hits	98
SwissProt Accessions	P10828, Q13986	Gene names	THRB, ERBA2, NR1A2, THR1
Domain Architecture
Description	Thyroid hormone receptor beta-1.

NR1H3_HUMAN
θ value	2.12192e-33 (rank : 50)	NC score	0.932897 (rank : 44)
Query Neighborhood Hits	223	Target Neighborhood Hits	104	Shared Neighborhood Hits	95
SwissProt Accessions	Q13133, Q96H87	Gene names	NR1H3, LXRA
Domain Architecture
Description	Oxysterols receptor LXR-alpha (Liver X receptor alpha) (Nuclear orphan receptor LXR-alpha).

PPARA_MOUSE
θ value	2.12192e-33 (rank : 51)	NC score	0.925383 (rank : 59)
Query Neighborhood Hits	223	Target Neighborhood Hits	99	Shared Neighborhood Hits	95
SwissProt Accessions	P23204	Gene names	Ppara, Nr1c1, Ppar
Domain Architecture
Description	Peroxisome proliferator-activated receptor alpha (PPAR-alpha).

THB1_MOUSE
θ value	2.12192e-33 (rank : 52)	NC score	0.920754 (rank : 68)
Query Neighborhood Hits	223	Target Neighborhood Hits	105	Shared Neighborhood Hits	98
SwissProt Accessions	P37242	Gene names	Thrb, C-erba-beta, Nr1a2
Domain Architecture
Description	Thyroid hormone receptor beta-1.

THB2_MOUSE
θ value	2.12192e-33 (rank : 53)	NC score	0.920781 (rank : 67)
Query Neighborhood Hits	223	Target Neighborhood Hits	106	Shared Neighborhood Hits	98
SwissProt Accessions	P37244	Gene names	Thrb, C-erba-beta, Nr1a2
Domain Architecture
Description	Thyroid hormone receptor beta-2.

THB2_HUMAN
θ value	2.77131e-33 (rank : 54)	NC score	0.922106 (rank : 63)
Query Neighborhood Hits	223	Target Neighborhood Hits	104	Shared Neighborhood Hits	98
SwissProt Accessions	P37243	Gene names	THRB, ERBA2, NR1A2, THR1
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor beta-2.

PPARG_HUMAN
θ value	3.61944e-33 (rank : 55)	NC score	0.920594 (rank : 70)
Query Neighborhood Hits	223	Target Neighborhood Hits	97	Shared Neighborhood Hits	94
SwissProt Accessions	P37231, O00684, O00710, O14515, Q15178, Q15179, Q15180, Q15832, Q86U60, Q96J12	Gene names	PPARG, NR1C3
Domain Architecture
Description	Peroxisome proliferator-activated receptor gamma (PPAR-gamma).

PPARG_MOUSE
θ value	8.06329e-33 (rank : 56)	NC score	0.920163 (rank : 71)
Query Neighborhood Hits	223	Target Neighborhood Hits	97	Shared Neighborhood Hits	94
SwissProt Accessions	P37238	Gene names	Pparg, Nr1c3
Domain Architecture
Description	Peroxisome proliferator-activated receptor gamma (PPAR-gamma).

NR1H3_MOUSE
θ value	1.0531e-32 (rank : 57)	NC score	0.932212 (rank : 46)
Query Neighborhood Hits	223	Target Neighborhood Hits	102	Shared Neighborhood Hits	94
SwissProt Accessions	Q9Z0Y9, Q9QUH7	Gene names	Nr1h3, Lxra
Domain Architecture
Description	Oxysterols receptor LXR-alpha (Liver X receptor alpha) (Nuclear orphan receptor LXR-alpha).

NR1H4_HUMAN
θ value	8.91499e-32 (rank : 58)	NC score	0.932774 (rank : 45)
Query Neighborhood Hits	223	Target Neighborhood Hits	112	Shared Neighborhood Hits	97
SwissProt Accessions	Q96RI1, Q8NFP5, Q8NFP6, Q92943	Gene names	NR1H4, BAR, FXR, HRR1, RIP14
Domain Architecture
Description	Bile acid receptor (Farnesoid X-activated receptor) (Farnesol receptor HRR-1) (Retinoid X receptor-interacting protein 14) (RXR-interacting protein 14).

NR1H4_MOUSE
θ value	1.98606e-31 (rank : 59)	NC score	0.932150 (rank : 47)
Query Neighborhood Hits	223	Target Neighborhood Hits	113	Shared Neighborhood Hits	97
SwissProt Accessions	Q60641, Q60642, Q60643	Gene names	Nr1h4, Bar, Fxr, Rip14
Domain Architecture
Description	Bile acid receptor (Farnesoid X-activated receptor) (Farnesol receptor HRR-1) (Retinoid X receptor-interacting protein 14) (RXR-interacting protein 14).

NR5A2_HUMAN
θ value	1.98606e-31 (rank : 60)	NC score	0.922528 (rank : 62)
Query Neighborhood Hits	223	Target Neighborhood Hits	112	Shared Neighborhood Hits	99
SwissProt Accessions	O00482, O95642	Gene names	NR5A2, B1F, CPF, FTF
Domain Architecture
Description	Orphan nuclear receptor NR5A2 (Alpha-1-fetoprotein transcription factor) (Hepatocytic transcription factor) (B1-binding factor) (hB1F) (CYP7A promoter-binding factor) (Liver receptor homolog 1) (LRH-1).

TR4_HUMAN
θ value	2.59387e-31 (rank : 61)	NC score	0.926725 (rank : 55)
Query Neighborhood Hits	223	Target Neighborhood Hits	117	Shared Neighborhood Hits	100
SwissProt Accessions	P49116, P55092	Gene names	NR2C2, TAK1, TR4
Domain Architecture
Description	Orphan nuclear receptor TR4 (Orphan nuclear receptor TAK1).

NR5A2_MOUSE
θ value	9.8567e-31 (rank : 62)	NC score	0.924352 (rank : 60)
Query Neighborhood Hits	223	Target Neighborhood Hits	107	Shared Neighborhood Hits	98
SwissProt Accessions	P45448	Gene names	Nr5a2, Lrh1
Domain Architecture
Description	Orphan nuclear receptor NR5A2 (Liver receptor homolog 1) (LRH-1).

TR4_MOUSE
θ value	1.6813e-30 (rank : 63)	NC score	0.926006 (rank : 57)
Query Neighborhood Hits	223	Target Neighborhood Hits	115	Shared Neighborhood Hits	99
SwissProt Accessions	P49117, P55093	Gene names	Nr2c2, Mtr2r1, Tak1, Tr4
Domain Architecture
Description	Orphan nuclear receptor TR4 (Orphan nuclear receptor TAK1).

TR2_MOUSE
θ value	1.4233e-29 (rank : 64)	NC score	0.926812 (rank : 54)
Query Neighborhood Hits	223	Target Neighborhood Hits	100	Shared Neighborhood Hits	98
SwissProt Accessions	Q505F1, P97763, Q3UIJ7, Q4U1Z4, Q60927, Q62152, Q8VIJ3	Gene names	Nr2c1, Tr2, Tr2-11
Domain Architecture	No domain graphic available
Description	Orphan nuclear receptor TR2 (Testicular receptor 2) (mTR2).

TR2_HUMAN
θ value	2.42779e-29 (rank : 65)	NC score	0.930284 (rank : 49)
Query Neighborhood Hits	223	Target Neighborhood Hits	110	Shared Neighborhood Hits	97
SwissProt Accessions	P13056	Gene names	NR2C1, TR2
Domain Architecture
Description	Orphan nuclear receptor TR2 (Testicular receptor 2).

NR1H2_HUMAN
θ value	5.40856e-29 (rank : 66)	NC score	0.914619 (rank : 74)
Query Neighborhood Hits	223	Target Neighborhood Hits	114	Shared Neighborhood Hits	96
SwissProt Accessions	P55055, Q12970	Gene names	NR1H2, LXRB, NER, UNR
Domain Architecture
Description	Oxysterols receptor LXR-beta (Liver X receptor beta) (Nuclear orphan receptor LXR-beta) (Ubiquitously-expressed nuclear receptor) (Nuclear receptor NER).

NR1H2_MOUSE
θ value	5.40856e-29 (rank : 67)	NC score	0.920736 (rank : 69)
Query Neighborhood Hits	223	Target Neighborhood Hits	109	Shared Neighborhood Hits	97
SwissProt Accessions	Q60644	Gene names	Nr1h2, Lxrb, Rip15, Unr, Unr2
Domain Architecture
Description	Oxysterols receptor LXR-beta (Liver X receptor beta) (Nuclear orphan receptor LXR-beta) (Ubiquitously-expressed nuclear receptor) (Retinoid X receptor-interacting protein No.15).

ANDR_MOUSE
θ value	5.59698e-26 (rank : 68)	NC score	0.883451 (rank : 88)
Query Neighborhood Hits	223	Target Neighborhood Hits	133	Shared Neighborhood Hits	95
SwissProt Accessions	P19091	Gene names	Ar, Nr3c4
Domain Architecture
Description	Androgen receptor (Dihydrotestosterone receptor).

GCR_HUMAN
θ value	1.62847e-25 (rank : 69)	NC score	0.885240 (rank : 87)
Query Neighborhood Hits	223	Target Neighborhood Hits	113	Shared Neighborhood Hits	94
SwissProt Accessions	P04150, P04151, Q53EP5, Q6N0A4	Gene names	NR3C1, GRL
Domain Architecture
Description	Glucocorticoid receptor (GR).

PXR_MOUSE
θ value	2.12685e-25 (rank : 70)	NC score	0.909829 (rank : 75)
Query Neighborhood Hits	223	Target Neighborhood Hits	107	Shared Neighborhood Hits	97
SwissProt Accessions	O54915	Gene names	Nr1i2, Pxr
Domain Architecture
Description	Orphan nuclear receptor PXR (Pregnane X receptor).

RORA_HUMAN
θ value	2.12685e-25 (rank : 71)	NC score	0.900413 (rank : 84)
Query Neighborhood Hits	223	Target Neighborhood Hits	105	Shared Neighborhood Hits	94
SwissProt Accessions	P35398, P35397, P35399, P45445, Q96H83	Gene names	RORA, NR1F1, RZRA
Domain Architecture
Description	Nuclear receptor ROR-alpha (Nuclear receptor RZR-alpha).

RORA_MOUSE
θ value	2.12685e-25 (rank : 72)	NC score	0.899846 (rank : 85)
Query Neighborhood Hits	223	Target Neighborhood Hits	105	Shared Neighborhood Hits	94
SwissProt Accessions	P51448, P70283, P97741, P97773, Q923G1	Gene names	Rora, Nr1f1, Rzra
Domain Architecture
Description	Nuclear receptor ROR-alpha (Nuclear receptor RZR-alpha).

PRGR_MOUSE
θ value	4.73814e-25 (rank : 73)	NC score	0.870063 (rank : 94)
Query Neighborhood Hits	223	Target Neighborhood Hits	286	Shared Neighborhood Hits	105
SwissProt Accessions	Q00175	Gene names	Pgr, Nr3c3, Pr
Domain Architecture
Description	Progesterone receptor (PR).

GCR_MOUSE
θ value	8.08199e-25 (rank : 74)	NC score	0.879325 (rank : 90)
Query Neighborhood Hits	223	Target Neighborhood Hits	117	Shared Neighborhood Hits	94
SwissProt Accessions	P06537, Q61628, Q61629	Gene names	Nr3c1, Grl, Grl1
Domain Architecture
Description	Glucocorticoid receptor (GR).

STF1_HUMAN
θ value	8.08199e-25 (rank : 75)	NC score	0.919612 (rank : 72)
Query Neighborhood Hits	223	Target Neighborhood Hits	132	Shared Neighborhood Hits	99
SwissProt Accessions	Q13285, O15196	Gene names	NR5A1, AD4BP, FTZF1, SF1
Domain Architecture
Description	Steroidogenic factor 1 (STF-1) (SF-1) (Adrenal 4-binding protein) (Steroid hormone receptor Ad4BP) (Fushi tarazu factor homolog 1).

STF1_MOUSE
θ value	8.08199e-25 (rank : 76)	NC score	0.921769 (rank : 64)
Query Neighborhood Hits	223	Target Neighborhood Hits	137	Shared Neighborhood Hits	99
SwissProt Accessions	P33242	Gene names	Nr5a1, Ftzf1
Domain Architecture
Description	Steroidogenic factor 1 (STF-1) (SF-1) (Adrenal 4-binding protein) (Steroid hormone receptor Ad4BP) (Fushi tarazu factor homolog 1) (Embryonal LTR-binding protein) (ELP) (Embryonal long terminal repeat- binding protein) (Steroid hydroxylase positive regulator).

RORB_HUMAN
θ value	1.05554e-24 (rank : 77)	NC score	0.900520 (rank : 83)
Query Neighborhood Hits	223	Target Neighborhood Hits	99	Shared Neighborhood Hits	94
SwissProt Accessions	Q92753, Q8WX73	Gene names	RORB, NR1F2, RZRB
Domain Architecture
Description	Nuclear receptor ROR-beta (Nuclear receptor RZR-beta).

RORB_MOUSE
θ value	1.05554e-24 (rank : 78)	NC score	0.900532 (rank : 82)
Query Neighborhood Hits	223	Target Neighborhood Hits	99	Shared Neighborhood Hits	94
SwissProt Accessions	Q8R1B8	Gene names	Rorb, Nr1f2
Domain Architecture
Description	Nuclear receptor ROR-beta (Nuclear receptor RZR-beta).

NR1I3_HUMAN
θ value	1.37858e-24 (rank : 79)	NC score	0.930007 (rank : 51)
Query Neighborhood Hits	223	Target Neighborhood Hits	107	Shared Neighborhood Hits	98
SwissProt Accessions	Q14994	Gene names	NR1I3, CAR
Domain Architecture
Description	Orphan nuclear receptor NR1I3 (Constitutive androstane receptor) (CAR) (Constitutive activator of retinoid response) (Constitutive active response) (Orphan nuclear receptor MB67).

NR1I3_MOUSE
θ value	2.35151e-24 (rank : 80)	NC score	0.925632 (rank : 58)
Query Neighborhood Hits	223	Target Neighborhood Hits	103	Shared Neighborhood Hits	98
SwissProt Accessions	O35627, O35628	Gene names	Nr1i3, Car
Domain Architecture
Description	Orphan nuclear receptor NR1I3 (Constitutive androstane receptor) (CAR) (Orphan nuclear receptor MB67).

NR6A1_HUMAN
θ value	2.35151e-24 (rank : 81)	NC score	0.930766 (rank : 48)
Query Neighborhood Hits	223	Target Neighborhood Hits	108	Shared Neighborhood Hits	98
SwissProt Accessions	Q15406, O00551, O00603, Q8NHQ0, Q92898, Q99802	Gene names	NR6A1, GCNF
Domain Architecture
Description	Orphan nuclear receptor NR6A1 (Germ cell nuclear factor) (GCNF) (Retinoid receptor-related testis-specific receptor) (RTR).

NR6A1_MOUSE
θ value	2.35151e-24 (rank : 82)	NC score	0.930064 (rank : 50)
Query Neighborhood Hits	223	Target Neighborhood Hits	110	Shared Neighborhood Hits	98
SwissProt Accessions	Q64249	Gene names	Nr6a1, Gcnf
Domain Architecture
Description	Orphan nuclear receptor NR6A1 (Germ cell nuclear factor) (GCNF) (Retinoid receptor-related testis-specific receptor) (RTR).

PRGR_HUMAN
θ value	2.35151e-24 (rank : 83)	NC score	0.874716 (rank : 92)
Query Neighborhood Hits	223	Target Neighborhood Hits	163	Shared Neighborhood Hits	98
SwissProt Accessions	P06401, Q9UPF7	Gene names	PGR, NR3C3
Domain Architecture
Description	Progesterone receptor (PR).

PXR_HUMAN
θ value	4.01107e-24 (rank : 84)	NC score	0.907300 (rank : 77)
Query Neighborhood Hits	223	Target Neighborhood Hits	107	Shared Neighborhood Hits	97
SwissProt Accessions	O75469, Q96AC7, Q9UJ22, Q9UJ23, Q9UJ24, Q9UJ25, Q9UJ26, Q9UJ27	Gene names	NR1I2, PXR
Domain Architecture
Description	Orphan nuclear receptor PXR (Pregnane X receptor) (Orphan nuclear receptor PAR1) (Steroid and xenobiotic receptor) (SXR).

RORG_HUMAN
θ value	4.01107e-24 (rank : 85)	NC score	0.898999 (rank : 86)
Query Neighborhood Hits	223	Target Neighborhood Hits	119	Shared Neighborhood Hits	95
SwissProt Accessions	P51449, Q8N5V7, Q8NCY8	Gene names	RORC, NR1F3, RORG, RZRG
Domain Architecture
Description	Nuclear receptor ROR-gamma (Nuclear receptor RZR-gamma).

RORG_MOUSE
θ value	1.16704e-23 (rank : 86)	NC score	0.902431 (rank : 81)
Query Neighborhood Hits	223	Target Neighborhood Hits	107	Shared Neighborhood Hits	95
SwissProt Accessions	P51450, Q61027, Q91YT5, Q9QXD9, Q9R177	Gene names	Rorc, Nr1f3, Rorg, Thor
Domain Architecture
Description	Nuclear receptor ROR-gamma (Nuclear receptor RZR-gamma) (Thymus orphan receptor) (TOR).

MCR_HUMAN
θ value	2.59989e-23 (rank : 87)	NC score	0.877950 (rank : 91)
Query Neighborhood Hits	223	Target Neighborhood Hits	149	Shared Neighborhood Hits	100
SwissProt Accessions	P08235, Q96KQ8, Q96KQ9	Gene names	NR3C2, MCR, MLR
Domain Architecture
Description	Mineralocorticoid receptor (MR).

NR1D2_HUMAN
θ value	9.87957e-23 (rank : 88)	NC score	0.908373 (rank : 76)
Query Neighborhood Hits	223	Target Neighborhood Hits	115	Shared Neighborhood Hits	94
SwissProt Accessions	Q14995, O00402, Q86XD4	Gene names	NR1D2
Domain Architecture
Description	Orphan nuclear receptor NR1D2 (Rev-erb-beta) (EAR-1R) (Orphan nuclear hormone receptor BD73).

ANDR_HUMAN
θ value	1.29031e-22 (rank : 89)	NC score	0.881044 (rank : 89)
Query Neighborhood Hits	223	Target Neighborhood Hits	126	Shared Neighborhood Hits	97
SwissProt Accessions	P10275	Gene names	AR, DHTR, NR3C4
Domain Architecture
Description	Androgen receptor (Dihydrotestosterone receptor).

NR1D2_MOUSE
θ value	2.20094e-22 (rank : 90)	NC score	0.905771 (rank : 80)
Query Neighborhood Hits	223	Target Neighborhood Hits	109	Shared Neighborhood Hits	94
SwissProt Accessions	Q60674, Q60646	Gene names	Nr1d2
Domain Architecture
Description	Orphan nuclear receptor NR1D2 (Rev-erb-beta) (Orphan nuclear receptor RVR).

MCR_MOUSE
θ value	8.36355e-22 (rank : 91)	NC score	0.873523 (rank : 93)
Query Neighborhood Hits	223	Target Neighborhood Hits	162	Shared Neighborhood Hits	102
SwissProt Accessions	Q8VII8, Q8VII9	Gene names	Nr3c2, Mlr
Domain Architecture	No domain graphic available
Description	Mineralocorticoid receptor (MR).

NR1D1_HUMAN
θ value	1.42661e-21 (rank : 92)	NC score	0.914935 (rank : 73)
Query Neighborhood Hits	223	Target Neighborhood Hits	140	Shared Neighborhood Hits	96
SwissProt Accessions	P20393, Q15304	Gene names	NR1D1, EAR1, HREV, THRAL
Domain Architecture
Description	Orphan nuclear receptor NR1D1 (V-erbA-related protein EAR-1) (Rev- erbA-alpha).

VDR_MOUSE
θ value	1.47631e-18 (rank : 93)	NC score	0.906699 (rank : 78)
Query Neighborhood Hits	223	Target Neighborhood Hits	103	Shared Neighborhood Hits	96
SwissProt Accessions	P48281	Gene names	Vdr, Nr1i1
Domain Architecture
Description	Vitamin D3 receptor (VDR) (1,25-dihydroxyvitamin D3 receptor).

VDR_HUMAN
θ value	1.92812e-18 (rank : 94)	NC score	0.906576 (rank : 79)
Query Neighborhood Hits	223	Target Neighborhood Hits	112	Shared Neighborhood Hits	96
SwissProt Accessions	P11473	Gene names	VDR, NR1I1
Domain Architecture
Description	Vitamin D3 receptor (VDR) (1,25-dihydroxyvitamin D3 receptor).

SHP_HUMAN
θ value	8.67504e-11 (rank : 95)	NC score	0.597473 (rank : 95)
Query Neighborhood Hits	223	Target Neighborhood Hits	57	Shared Neighborhood Hits	56
SwissProt Accessions	Q15466, Q5QP36	Gene names	NR0B2, SHP
Domain Architecture
Description	Nuclear receptor 0B2 (Orphan nuclear receptor SHP) (Small heterodimer partner).

DAX1_HUMAN
θ value	1.47974e-10 (rank : 96)	NC score	0.556164 (rank : 98)
Query Neighborhood Hits	223	Target Neighborhood Hits	65	Shared Neighborhood Hits	59
SwissProt Accessions	P51843, Q96F69	Gene names	NR0B1, AHC, DAX1
Domain Architecture
Description	Nuclear receptor 0B1 (Nuclear receptor DAX-1) (DSS-AHC critical region on the X chromosome protein 1).

SHP_MOUSE
θ value	2.52405e-10 (rank : 97)	NC score	0.586770 (rank : 96)
Query Neighborhood Hits	223	Target Neighborhood Hits	53	Shared Neighborhood Hits	53
SwissProt Accessions	Q62227, Q53Z53	Gene names	Nr0b2, Shp
Domain Architecture
Description	Nuclear receptor 0B2 (Orphan nuclear receptor SHP) (Small heterodimer partner).

DAX1_MOUSE
θ value	4.30538e-10 (rank : 98)	NC score	0.578905 (rank : 97)
Query Neighborhood Hits	223	Target Neighborhood Hits	70	Shared Neighborhood Hits	60
SwissProt Accessions	Q61066, O09068, O09147	Gene names	Nr0b1, Ahch, Dax1
Domain Architecture
Description	Nuclear receptor 0B1 (Nuclear receptor DAX-1).

BCL9_HUMAN
θ value	0.00228821 (rank : 99)	NC score	0.050681 (rank : 100)
Query Neighborhood Hits	223	Target Neighborhood Hits	1008	Shared Neighborhood Hits	83
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

BCL9_MOUSE
θ value	0.00298849 (rank : 100)	NC score	0.055818 (rank : 99)
Query Neighborhood Hits	223	Target Neighborhood Hits	770	Shared Neighborhood Hits	68
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

EP300_HUMAN
θ value	0.0113563 (rank : 101)	NC score	0.034973 (rank : 101)
Query Neighborhood Hits	223	Target Neighborhood Hits	821	Shared Neighborhood Hits	45
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

CBP_HUMAN
θ value	0.0330416 (rank : 102)	NC score	0.031700 (rank : 103)
Query Neighborhood Hits	223	Target Neighborhood Hits	941	Shared Neighborhood Hits	58
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

WNK4_HUMAN
θ value	0.0431538 (rank : 103)	NC score	-0.002236 (rank : 211)
Query Neighborhood Hits	223	Target Neighborhood Hits	1043	Shared Neighborhood Hits	22
SwissProt Accessions	Q96J92, Q8N8X3, Q8N8Z2, Q96DT8, Q9BYS5	Gene names	WNK4, PRKWNK4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

GLIS1_MOUSE
θ value	0.0961366 (rank : 104)	NC score	-0.003735 (rank : 212)
Query Neighborhood Hits	223	Target Neighborhood Hits	751	Shared Neighborhood Hits	9
SwissProt Accessions	Q8K1M4, Q6NZF6, Q8R4Z3	Gene names	Glis1, Gli5
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLIS1 (GLI-similar 1) (Gli homologous protein 1) (GliH1).

UBQL2_MOUSE
θ value	0.0961366 (rank : 105)	NC score	0.014483 (rank : 118)
Query Neighborhood Hits	223	Target Neighborhood Hits	114	Shared Neighborhood Hits	7
SwissProt Accessions	Q9QZM0, Q7TSJ8, Q8VDH9	Gene names	Ubqln2, Plic2
Domain Architecture
Description	Ubiquilin-2 (Protein linking IAP with cytoskeleton 2) (PLIC-2) (Ubiquitin-like product Chap1/Dsk2) (DSK2 homolog) (Chap1).

PRDM2_HUMAN
θ value	0.163984 (rank : 106)	NC score	-0.001104 (rank : 210)
Query Neighborhood Hits	223	Target Neighborhood Hits	1135	Shared Neighborhood Hits	27
SwissProt Accessions	Q13029, Q13149, Q14550, Q5VUL9	Gene names	PRDM2, RIZ
Domain Architecture
Description	PR domain zinc finger protein 2 (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc-finger protein) (Zinc finger protein RIZ) (MTE-binding protein) (MTB-ZF) (GATA-3-binding protein G3B).

CBP_MOUSE
θ value	0.279714 (rank : 107)	NC score	0.034541 (rank : 102)
Query Neighborhood Hits	223	Target Neighborhood Hits	1051	Shared Neighborhood Hits	65
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

HCN4_MOUSE
θ value	0.279714 (rank : 108)	NC score	0.005891 (rank : 178)
Query Neighborhood Hits	223	Target Neighborhood Hits	284	Shared Neighborhood Hits	17
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

MA2C1_HUMAN
θ value	0.279714 (rank : 109)	NC score	0.026228 (rank : 106)
Query Neighborhood Hits	223	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NTJ4, Q13358, Q9UL64	Gene names	MAN2C1
Domain Architecture
Description	Alpha-mannosidase 2C1 (EC 3.2.1.24) (Alpha-D-mannoside mannohydrolase) (Mannosidase alpha class 2C member 1) (Alpha mannosidase 6A8B).

SMCA2_HUMAN
θ value	0.279714 (rank : 110)	NC score	0.006349 (rank : 174)
Query Neighborhood Hits	223	Target Neighborhood Hits	503	Shared Neighborhood Hits	28
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

DEN1A_MOUSE
θ value	0.365318 (rank : 111)	NC score	0.010435 (rank : 134)
Query Neighborhood Hits	223	Target Neighborhood Hits	178	Shared Neighborhood Hits	16
SwissProt Accessions	Q8K382	Gene names	Dennd1a
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 1A.

MAGE1_HUMAN
θ value	0.365318 (rank : 112)	NC score	0.026534 (rank : 104)
Query Neighborhood Hits	223	Target Neighborhood Hits	1389	Shared Neighborhood Hits	90
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

PAPOA_MOUSE
θ value	0.365318 (rank : 113)	NC score	0.008343 (rank : 161)
Query Neighborhood Hits	223	Target Neighborhood Hits	115	Shared Neighborhood Hits	6
SwissProt Accessions	Q61183, Q61208, Q61209, Q8K4X2	Gene names	Papola, Pap, Plap
Domain Architecture
Description	Poly(A) polymerase alpha (EC 2.7.7.19) (PAP) (Polynucleotide adenylyltransferase).

DIAP3_HUMAN
θ value	0.47712 (rank : 114)	NC score	0.006176 (rank : 177)
Query Neighborhood Hits	223	Target Neighborhood Hits	209	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NSV4, Q5T2S7, Q5XKF6, Q6MZF0, Q6NUP0, Q86VS4, Q8NAV4	Gene names	DIAPH3, DIAP3
Domain Architecture	No domain graphic available
Description	Protein diaphanous homolog 3 (Diaphanous-related formin-3) (DRF3).

MUC5B_HUMAN
θ value	0.47712 (rank : 115)	NC score	0.008838 (rank : 152)
Query Neighborhood Hits	223	Target Neighborhood Hits	1020	Shared Neighborhood Hits	42
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

UBQL2_HUMAN
θ value	0.47712 (rank : 116)	NC score	0.012830 (rank : 124)
Query Neighborhood Hits	223	Target Neighborhood Hits	103	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UHD9, O94798, Q9H3W6, Q9HAZ4	Gene names	UBQLN2, PLIC2
Domain Architecture
Description	Ubiquilin-2 (Protein linking IAP with cytoskeleton 2) (PLIC-2) (hPLIC- 2) (Ubiquitin-like product Chap1/Dsk2) (DSK2 homolog) (Chap1).

AATK_HUMAN
θ value	0.62314 (rank : 117)	NC score	-0.004759 (rank : 213)
Query Neighborhood Hits	223	Target Neighborhood Hits	1243	Shared Neighborhood Hits	44
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

ADRM1_HUMAN
θ value	0.62314 (rank : 118)	NC score	0.022433 (rank : 107)
Query Neighborhood Hits	223	Target Neighborhood Hits	81	Shared Neighborhood Hits	10
SwissProt Accessions	Q16186, Q9H1P2	Gene names	ADRM1, GP110
Domain Architecture
Description	Adhesion-regulating molecule 1 precursor (110 kDa cell membrane glycoprotein) (Gp110).

CCNK_MOUSE
θ value	0.62314 (rank : 119)	NC score	0.010942 (rank : 132)
Query Neighborhood Hits	223	Target Neighborhood Hits	350	Shared Neighborhood Hits	16
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

PER3_HUMAN
θ value	0.62314 (rank : 120)	NC score	0.021204 (rank : 110)
Query Neighborhood Hits	223	Target Neighborhood Hits	479	Shared Neighborhood Hits	50
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

RHG26_HUMAN
θ value	0.62314 (rank : 121)	NC score	0.002499 (rank : 196)
Query Neighborhood Hits	223	Target Neighborhood Hits	281	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

GLIS1_HUMAN
θ value	0.813845 (rank : 122)	NC score	-0.005573 (rank : 216)
Query Neighborhood Hits	223	Target Neighborhood Hits	748	Shared Neighborhood Hits	9
SwissProt Accessions	Q8NBF1, Q8N9V9	Gene names	GLIS1
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLIS1 (GLI-similar 1).

MUC13_MOUSE
θ value	0.813845 (rank : 123)	NC score	0.008419 (rank : 158)
Query Neighborhood Hits	223	Target Neighborhood Hits	447	Shared Neighborhood Hits	16
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

MUC2_HUMAN
θ value	0.813845 (rank : 124)	NC score	0.010183 (rank : 135)
Query Neighborhood Hits	223	Target Neighborhood Hits	906	Shared Neighborhood Hits	34
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

SFPQ_MOUSE
θ value	0.813845 (rank : 125)	NC score	0.006802 (rank : 172)
Query Neighborhood Hits	223	Target Neighborhood Hits	958	Shared Neighborhood Hits	29
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

ZC3H5_MOUSE
θ value	0.813845 (rank : 126)	NC score	0.010094 (rank : 137)
Query Neighborhood Hits	223	Target Neighborhood Hits	136	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BL48, Q8BVI6, Q99JZ8, Q99LL9	Gene names	Zc3h5, Kiaa1753, Zc3hdc5
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 5.

4ET_MOUSE
θ value	1.06291 (rank : 127)	NC score	0.012580 (rank : 126)
Query Neighborhood Hits	223	Target Neighborhood Hits	103	Shared Neighborhood Hits	8
SwissProt Accessions	Q9EST3, Q9CSS3	Gene names	Eif4enif1, Clast4
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4E transporter (eIF4E transporter) (4E-T) (Eukaryotic translation initiation factor 4E nuclear import factor 1).

CNTRB_MOUSE
θ value	1.06291 (rank : 128)	NC score	-0.000781 (rank : 208)
Query Neighborhood Hits	223	Target Neighborhood Hits	1029	Shared Neighborhood Hits	23
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

CS007_MOUSE
θ value	1.06291 (rank : 129)	NC score	0.011405 (rank : 128)
Query Neighborhood Hits	223	Target Neighborhood Hits	464	Shared Neighborhood Hits	29
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

CSKI2_MOUSE
θ value	1.06291 (rank : 130)	NC score	0.000082 (rank : 205)
Query Neighborhood Hits	223	Target Neighborhood Hits	812	Shared Neighborhood Hits	38
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

ENAH_MOUSE
θ value	1.06291 (rank : 131)	NC score	0.008447 (rank : 156)
Query Neighborhood Hits	223	Target Neighborhood Hits	919	Shared Neighborhood Hits	26
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

EP400_HUMAN
θ value	1.06291 (rank : 132)	NC score	0.009975 (rank : 138)
Query Neighborhood Hits	223	Target Neighborhood Hits	556	Shared Neighborhood Hits	31
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

MA2C1_MOUSE
θ value	1.06291 (rank : 133)	NC score	0.022333 (rank : 108)
Query Neighborhood Hits	223	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	Q91W89	Gene names	Man2c1
Domain Architecture
Description	Alpha-mannosidase 2C1 (EC 3.2.1.24) (Alpha-D-mannoside mannohydrolase) (Mannosidase alpha class 2C member 1).

MINT_MOUSE
θ value	1.06291 (rank : 134)	NC score	0.009576 (rank : 142)
Query Neighborhood Hits	223	Target Neighborhood Hits	1514	Shared Neighborhood Hits	61
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MUC1_MOUSE
θ value	1.06291 (rank : 135)	NC score	0.020623 (rank : 111)
Query Neighborhood Hits	223	Target Neighborhood Hits	388	Shared Neighborhood Hits	32
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

NASP_HUMAN
θ value	1.06291 (rank : 136)	NC score	0.008633 (rank : 154)
Query Neighborhood Hits	223	Target Neighborhood Hits	709	Shared Neighborhood Hits	14
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

PO121_HUMAN
θ value	1.06291 (rank : 137)	NC score	0.016112 (rank : 113)
Query Neighborhood Hits	223	Target Neighborhood Hits	344	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

PO121_MOUSE
θ value	1.06291 (rank : 138)	NC score	0.014132 (rank : 120)
Query Neighborhood Hits	223	Target Neighborhood Hits	345	Shared Neighborhood Hits	23
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

SGIP1_MOUSE
θ value	1.06291 (rank : 139)	NC score	0.015094 (rank : 114)
Query Neighborhood Hits	223	Target Neighborhood Hits	180	Shared Neighborhood Hits	15
SwissProt Accessions	Q8VD37, Q3UFU3, Q3UGA0, Q8BXX4, Q8C034, Q9CXT2	Gene names	Sgip1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

TLE1_MOUSE
θ value	1.06291 (rank : 140)	NC score	0.007182 (rank : 167)
Query Neighborhood Hits	223	Target Neighborhood Hits	491	Shared Neighborhood Hits	32
SwissProt Accessions	Q62440	Gene names	Tle1, Grg1
Domain Architecture
Description	Transducin-like enhancer protein 1 (Groucho-related protein 1) (Grg- 1).

ADRM1_MOUSE
θ value	1.38821 (rank : 141)	NC score	0.021587 (rank : 109)
Query Neighborhood Hits	223	Target Neighborhood Hits	84	Shared Neighborhood Hits	11
SwissProt Accessions	Q9JKV1	Gene names	Adrm1, Gp110
Domain Architecture
Description	Adhesion-regulating molecule 1 precursor (110 kDa cell membrane glycoprotein) (Gp110) (ARM-1).

ARHG1_HUMAN
θ value	1.38821 (rank : 142)	NC score	0.002979 (rank : 193)
Query Neighborhood Hits	223	Target Neighborhood Hits	176	Shared Neighborhood Hits	6
SwissProt Accessions	Q92888, O00513, Q8N4J4, Q96BF4, Q96F17, Q9BSB1	Gene names	ARHGEF1
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (p115-RhoGEF) (p115RhoGEF) (115 kDa guanine nucleotide exchange factor) (Sub1.5).

ATF6B_MOUSE
θ value	1.38821 (rank : 143)	NC score	0.008597 (rank : 155)
Query Neighborhood Hits	223	Target Neighborhood Hits	97	Shared Neighborhood Hits	6
SwissProt Accessions	O35451	Gene names	Crebl1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 beta (Activating transcription factor 6 beta) (ATF6-beta) (cAMP-responsive element- binding protein-like 1) (cAMP response element-binding protein-related protein) (Creb-rp).

DAG1_MOUSE
θ value	1.38821 (rank : 144)	NC score	0.014748 (rank : 117)
Query Neighborhood Hits	223	Target Neighborhood Hits	100	Shared Neighborhood Hits	9
SwissProt Accessions	Q62165, Q61094, Q61141, Q61497	Gene names	Dag1, Dag-1
Domain Architecture
Description	Dystroglycan precursor (Dystrophin-associated glycoprotein 1) [Contains: Alpha-dystroglycan (Alpha-DG); Beta-dystroglycan (Beta- DG)].

GMEB2_HUMAN
θ value	1.38821 (rank : 145)	NC score	0.011108 (rank : 130)
Query Neighborhood Hits	223	Target Neighborhood Hits	62	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UKD1, Q5TDS0, Q9H431, Q9H4X7, Q9H4X8, Q9UF78, Q9ULF1	Gene names	GMEB2, KIAA1269
Domain Architecture
Description	Glucocorticoid modulatory element-binding protein 2 (GMEB-2) (Parvovirus initiation factor p79) (PIF p79) (DNA-binding protein p79PIF).

KS6B2_MOUSE
θ value	1.38821 (rank : 146)	NC score	-0.007781 (rank : 220)
Query Neighborhood Hits	223	Target Neighborhood Hits	871	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Z1M4	Gene names	Rps6kb2
Domain Architecture
Description	Ribosomal protein S6 kinase beta-2 (EC 2.7.11.1) (S6K-beta 2) (70 kDa ribosomal protein S6 kinase 2) (p70-S6KB) (p70 ribosomal S6 kinase beta) (p70 S6Kbeta) (S6K2).

MINT_HUMAN
θ value	1.38821 (rank : 147)	NC score	0.005192 (rank : 182)
Query Neighborhood Hits	223	Target Neighborhood Hits	1291	Shared Neighborhood Hits	39
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

TAB2_HUMAN
θ value	1.38821 (rank : 148)	NC score	0.008988 (rank : 151)
Query Neighborhood Hits	223	Target Neighborhood Hits	169	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NYJ8, O94838, Q6I9W8, Q76N06, Q9UFP7	Gene names	MAP3K7IP2, KIAA0733, TAB2
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 2 (TAK1-binding protein 2).

TENS4_MOUSE
θ value	1.38821 (rank : 149)	NC score	0.010124 (rank : 136)
Query Neighborhood Hits	223	Target Neighborhood Hits	225	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BZ33, Q3TCM8, Q7TNR5	Gene names	Tns4
Domain Architecture	No domain graphic available
Description	Tensin-4 precursor.

WFS1_HUMAN
θ value	1.38821 (rank : 150)	NC score	0.017846 (rank : 112)
Query Neighborhood Hits	223	Target Neighborhood Hits	42	Shared Neighborhood Hits	6
SwissProt Accessions	O76024, Q8N6I3, Q9UNW6	Gene names	WFS1
Domain Architecture	No domain graphic available
Description	Wolframin.

GGN_MOUSE
θ value	1.81305 (rank : 151)	NC score	0.011057 (rank : 131)
Query Neighborhood Hits	223	Target Neighborhood Hits	311	Shared Neighborhood Hits	18
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

PODXL_HUMAN
θ value	1.81305 (rank : 152)	NC score	0.014845 (rank : 116)
Query Neighborhood Hits	223	Target Neighborhood Hits	191	Shared Neighborhood Hits	19
SwissProt Accessions	O00592	Gene names	PODXL, PCLP, PCLP1
Domain Architecture
Description	Podocalyxin-like protein 1 precursor.

RGDSR_HUMAN
θ value	1.81305 (rank : 153)	NC score	0.006687 (rank : 173)
Query Neighborhood Hits	223	Target Neighborhood Hits	63	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IZJ4	Gene names	RGR
Domain Architecture
Description	Ral-GDS-related protein (hRGR).

RPB1_HUMAN
θ value	1.81305 (rank : 154)	NC score	0.009747 (rank : 140)
Query Neighborhood Hits	223	Target Neighborhood Hits	362	Shared Neighborhood Hits	18
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RPB1_MOUSE
θ value	1.81305 (rank : 155)	NC score	0.009808 (rank : 139)
Query Neighborhood Hits	223	Target Neighborhood Hits	363	Shared Neighborhood Hits	18
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

ZBTB3_MOUSE
θ value	1.81305 (rank : 156)	NC score	-0.006466 (rank : 218)
Query Neighborhood Hits	223	Target Neighborhood Hits	792	Shared Neighborhood Hits	7
SwissProt Accessions	Q91X45, Q8BIJ4	Gene names	Zbtb3
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 3.

CT112_HUMAN
θ value	2.36792 (rank : 157)	NC score	0.009683 (rank : 141)
Query Neighborhood Hits	223	Target Neighborhood Hits	30	Shared Neighborhood Hits	4
SwissProt Accessions	Q96MY1, Q5JYB7, Q6P0Y4, Q9BR34, Q9NQF6	Gene names	C20orf112
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf112.

CUTL2_HUMAN
θ value	2.36792 (rank : 158)	NC score	0.000736 (rank : 202)
Query Neighborhood Hits	223	Target Neighborhood Hits	906	Shared Neighborhood Hits	25
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

MUCDL_MOUSE
θ value	2.36792 (rank : 159)	NC score	0.005396 (rank : 180)
Query Neighborhood Hits	223	Target Neighborhood Hits	461	Shared Neighborhood Hits	28
SwissProt Accessions	Q8VHF2, Q8CEJ3, Q9D8I9	Gene names	Mucdhl
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

ROBO4_MOUSE
θ value	2.36792 (rank : 160)	NC score	-0.001059 (rank : 209)
Query Neighborhood Hits	223	Target Neighborhood Hits	358	Shared Neighborhood Hits	5
SwissProt Accessions	Q8C310, Q9DBW1	Gene names	Robo4
Domain Architecture
Description	Roundabout homolog 4 precursor.

ROD1_HUMAN
θ value	2.36792 (rank : 161)	NC score	0.003870 (rank : 187)
Query Neighborhood Hits	223	Target Neighborhood Hits	60	Shared Neighborhood Hits	5
SwissProt Accessions	O95758, Q86YB3, Q86YH9	Gene names	ROD1
Domain Architecture	No domain graphic available
Description	Regulator of differentiation 1 (Rod1).

S23IP_MOUSE
θ value	2.36792 (rank : 162)	NC score	0.014950 (rank : 115)
Query Neighborhood Hits	223	Target Neighborhood Hits	363	Shared Neighborhood Hits	39
SwissProt Accessions	Q6NZC7, Q8BXY6	Gene names	Sec23ip
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein.

SF3A2_MOUSE
θ value	2.36792 (rank : 163)	NC score	0.012649 (rank : 125)
Query Neighborhood Hits	223	Target Neighborhood Hits	247	Shared Neighborhood Hits	17
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

UBE4B_HUMAN
θ value	2.36792 (rank : 164)	NC score	0.007476 (rank : 166)
Query Neighborhood Hits	223	Target Neighborhood Hits	158	Shared Neighborhood Hits	13
SwissProt Accessions	O95155, O75169, O95338, Q5SZ12, Q5SZ16, Q96QD4, Q9BYI7	Gene names	UBE4B, HDNB1, KIAA0684, UFD2
Domain Architecture
Description	Ubiquitin conjugation factor E4 B (Ubiquitin fusion degradation protein 2) (Homozygously deleted in neuroblastoma 1).

ARI1A_HUMAN
θ value	3.0926 (rank : 165)	NC score	0.013154 (rank : 123)
Query Neighborhood Hits	223	Target Neighborhood Hits	787	Shared Neighborhood Hits	46
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

CHFR_HUMAN
θ value	3.0926 (rank : 166)	NC score	0.001738 (rank : 199)
Query Neighborhood Hits	223	Target Neighborhood Hits	255	Shared Neighborhood Hits	2
SwissProt Accessions	Q96EP1, Q96SL3, Q9NRT4, Q9NT32, Q9NVD5	Gene names	CHFR
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

DAG1_HUMAN
θ value	3.0926 (rank : 167)	NC score	0.014042 (rank : 121)
Query Neighborhood Hits	223	Target Neighborhood Hits	104	Shared Neighborhood Hits	10
SwissProt Accessions	Q14118	Gene names	DAG1
Domain Architecture
Description	Dystroglycan precursor (Dystrophin-associated glycoprotein 1) [Contains: Alpha-dystroglycan (Alpha-DG); Beta-dystroglycan (Beta- DG)].

KPCD1_HUMAN
θ value	3.0926 (rank : 168)	NC score	-0.007601 (rank : 219)
Query Neighborhood Hits	223	Target Neighborhood Hits	901	Shared Neighborhood Hits	9
SwissProt Accessions	Q15139	Gene names	PRKD1, PKD, PKD1, PRKCM
Domain Architecture
Description	Serine/threonine-protein kinase D1 (EC 2.7.11.13) (nPKC-D1) (Protein kinase D) (Protein kinase C mu type) (nPKC-mu).

MLL2_HUMAN
θ value	3.0926 (rank : 169)	NC score	0.004686 (rank : 183)
Query Neighborhood Hits	223	Target Neighborhood Hits	1788	Shared Neighborhood Hits	58
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

OLIG3_MOUSE
θ value	3.0926 (rank : 170)	NC score	0.003259 (rank : 191)
Query Neighborhood Hits	223	Target Neighborhood Hits	76	Shared Neighborhood Hits	3
SwissProt Accessions	Q6PFG8, Q9EQW5	Gene names	Olig3, Bhlhb7
Domain Architecture	No domain graphic available
Description	Oligodendrocyte transcription factor 3 (Oligo3) (Oligodendrocyte- specific bHLH transcription factor 3) (Basic helix-loop-helix domain- containing class B protein 7).

PCQAP_HUMAN
θ value	3.0926 (rank : 171)	NC score	0.004457 (rank : 185)
Query Neighborhood Hits	223	Target Neighborhood Hits	549	Shared Neighborhood Hits	19
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

PTN23_HUMAN
θ value	3.0926 (rank : 172)	NC score	0.001411 (rank : 200)
Query Neighborhood Hits	223	Target Neighborhood Hits	646	Shared Neighborhood Hits	24
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

SFPQ_HUMAN
θ value	3.0926 (rank : 173)	NC score	0.006228 (rank : 175)
Query Neighborhood Hits	223	Target Neighborhood Hits	986	Shared Neighborhood Hits	31
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

BRD7_HUMAN
θ value	4.03905 (rank : 174)	NC score	0.014208 (rank : 119)
Query Neighborhood Hits	223	Target Neighborhood Hits	94	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NPI1, Q4VC09, Q8N2L9, Q96KA4, Q9BV48, Q9UH59	Gene names	BRD7, BP75, CELTIX1
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 7 (75 kDa bromodomain protein) (Protein CELTIX-1).

BRD7_MOUSE
θ value	4.03905 (rank : 175)	NC score	0.013847 (rank : 122)
Query Neighborhood Hits	223	Target Neighborhood Hits	141	Shared Neighborhood Hits	8
SwissProt Accessions	O88665, Q3UQ56, Q3UU06, Q9CT78	Gene names	Brd7, Bp75
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 7 (75 kDa bromodomain protein).

CB017_HUMAN
θ value	4.03905 (rank : 176)	NC score	0.006859 (rank : 171)
Query Neighborhood Hits	223	Target Neighborhood Hits	38	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NC44, Q6P1P5, Q9H0K7	Gene names	C2orf17
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C2orf17.

CNOT3_MOUSE
θ value	4.03905 (rank : 177)	NC score	0.004248 (rank : 186)
Query Neighborhood Hits	223	Target Neighborhood Hits	504	Shared Neighborhood Hits	15
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

GMEB2_MOUSE
θ value	4.03905 (rank : 178)	NC score	0.009486 (rank : 143)
Query Neighborhood Hits	223	Target Neighborhood Hits	64	Shared Neighborhood Hits	5
SwissProt Accessions	P58929, Q6PCY0	Gene names	Gmeb2
Domain Architecture	No domain graphic available
Description	Glucocorticoid modulatory element-binding protein 2 (GMEB-2).

GPR64_HUMAN
θ value	4.03905 (rank : 179)	NC score	0.002935 (rank : 194)
Query Neighborhood Hits	223	Target Neighborhood Hits	207	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IZP9, O00406, Q8IWT2, Q8IZE4, Q8IZE5, Q8IZE6, Q8IZE7, Q8IZP3, Q8IZP4	Gene names	GPR64, HE6, TM7LN2
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (He6 receptor).

NCOA2_HUMAN
θ value	4.03905 (rank : 180)	NC score	0.007129 (rank : 168)
Query Neighborhood Hits	223	Target Neighborhood Hits	281	Shared Neighborhood Hits	26
SwissProt Accessions	Q15596	Gene names	NCOA2, TIF2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2).

NOTC3_MOUSE
θ value	4.03905 (rank : 181)	NC score	-0.006238 (rank : 217)
Query Neighborhood Hits	223	Target Neighborhood Hits	975	Shared Neighborhood Hits	12
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

RBM12_HUMAN
θ value	4.03905 (rank : 182)	NC score	0.009412 (rank : 144)
Query Neighborhood Hits	223	Target Neighborhood Hits	298	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NTZ6, O94865, Q8N3B1, Q9H196	Gene names	RBM12, KIAA0765
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

RBM12_MOUSE
θ value	4.03905 (rank : 183)	NC score	0.009015 (rank : 150)
Query Neighborhood Hits	223	Target Neighborhood Hits	313	Shared Neighborhood Hits	16
SwissProt Accessions	Q8R4X3, Q8K373, Q8R302, Q9CS80	Gene names	Rbm12
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

RIN3_MOUSE
θ value	4.03905 (rank : 184)	NC score	0.005440 (rank : 179)
Query Neighborhood Hits	223	Target Neighborhood Hits	239	Shared Neighborhood Hits	16
SwissProt Accessions	P59729	Gene names	Rin3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

SF01_HUMAN
θ value	4.03905 (rank : 185)	NC score	0.012327 (rank : 127)
Query Neighborhood Hits	223	Target Neighborhood Hits	287	Shared Neighborhood Hits	21
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

SF01_MOUSE
θ value	4.03905 (rank : 186)	NC score	0.011160 (rank : 129)
Query Neighborhood Hits	223	Target Neighborhood Hits	240	Shared Neighborhood Hits	17
SwissProt Accessions	Q64213, O08817, P70167, Q61454, Q921Z4	Gene names	Sf1, Zfm1, Zfp162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (mZFM) (Zinc finger gene in MEN1 locus) (Mammalian branch point- binding protein mBBP) (BBP) (CW17).

SRBP1_HUMAN
θ value	4.03905 (rank : 187)	NC score	0.006200 (rank : 176)
Query Neighborhood Hits	223	Target Neighborhood Hits	225	Shared Neighborhood Hits	14
SwissProt Accessions	P36956, Q16062	Gene names	SREBF1, SREBP1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

TCF7_HUMAN
θ value	4.03905 (rank : 188)	NC score	0.002397 (rank : 197)
Query Neighborhood Hits	223	Target Neighborhood Hits	186	Shared Neighborhood Hits	12
SwissProt Accessions	P36402, Q9UKI4	Gene names	TCF7, TCF1
Domain Architecture
Description	Transcription factor 7 (T-cell-specific transcription factor 1) (TCF- 1) (T-cell factor 1).

UBP2L_HUMAN
θ value	4.03905 (rank : 189)	NC score	0.009268 (rank : 145)
Query Neighborhood Hits	223	Target Neighborhood Hits	170	Shared Neighborhood Hits	11
SwissProt Accessions	Q14157, Q5VU75, Q5VU76, Q9BTU3, Q9UGL5	Gene names	UBAP2L, KIAA0144, NICE4
Domain Architecture
Description	Ubiquitin-associated protein 2-like (Protein NICE-4).

UBP2L_MOUSE
θ value	4.03905 (rank : 190)	NC score	0.009202 (rank : 146)
Query Neighborhood Hits	223	Target Neighborhood Hits	173	Shared Neighborhood Hits	11
SwissProt Accessions	Q80X50, Q8BIT6, Q8BIW4, Q8BJ01, Q8CIG7, Q8K102, Q9CRT6	Gene names	Ubap2l
Domain Architecture	No domain graphic available
Description	Ubiquitin-associated protein 2-like.

WNK1_HUMAN
θ value	4.03905 (rank : 191)	NC score	-0.004823 (rank : 215)
Query Neighborhood Hits	223	Target Neighborhood Hits	1158	Shared Neighborhood Hits	35
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

YLPM1_MOUSE
θ value	4.03905 (rank : 192)	NC score	0.007538 (rank : 165)
Query Neighborhood Hits	223	Target Neighborhood Hits	505	Shared Neighborhood Hits	25
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

CF142_MOUSE
θ value	5.27518 (rank : 193)	NC score	0.006919 (rank : 170)
Query Neighborhood Hits	223	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	Q5FW52, Q9D6X9	Gene names
Domain Architecture	No domain graphic available
Description	Protein C6orf142 homolog.

COHA1_MOUSE
θ value	5.27518 (rank : 194)	NC score	0.003223 (rank : 192)
Query Neighborhood Hits	223	Target Neighborhood Hits	414	Shared Neighborhood Hits	25
SwissProt Accessions	Q07563, Q99LK8	Gene names	Col17a1, Bp180, Bpag2
Domain Architecture
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

CT112_MOUSE
θ value	5.27518 (rank : 195)	NC score	0.008179 (rank : 162)
Query Neighborhood Hits	223	Target Neighborhood Hits	35	Shared Neighborhood Hits	4
SwissProt Accessions	Q6DIB4	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf112 homolog.

MMP9_MOUSE
θ value	5.27518 (rank : 196)	NC score	0.000085 (rank : 204)
Query Neighborhood Hits	223	Target Neighborhood Hits	151	Shared Neighborhood Hits	6
SwissProt Accessions	P41245, Q06788, Q9DC02	Gene names	Mmp9, Clg4b
Domain Architecture
Description	Matrix metalloproteinase-9 precursor (EC 3.4.24.35) (MMP-9) (92 kDa type IV collagenase) (92 kDa gelatinase) (Gelatinase B) (GELB).

SC24C_HUMAN
θ value	5.27518 (rank : 197)	NC score	0.026469 (rank : 105)
Query Neighborhood Hits	223	Target Neighborhood Hits	662	Shared Neighborhood Hits	69
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

SMR3A_HUMAN
θ value	5.27518 (rank : 198)	NC score	0.007545 (rank : 164)
Query Neighborhood Hits	223	Target Neighborhood Hits	93	Shared Neighborhood Hits	5
SwissProt Accessions	Q99954	Gene names	SMR3A, PBI, PROL5
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog A precursor (Proline-rich protein 5) (Proline-rich protein PBI).

SNTB2_HUMAN
θ value	5.27518 (rank : 199)	NC score	-0.000449 (rank : 207)
Query Neighborhood Hits	223	Target Neighborhood Hits	180	Shared Neighborhood Hits	3
SwissProt Accessions	Q13425, Q9BY09	Gene names	SNTB2, SNT2B2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

TAB3_HUMAN
θ value	5.27518 (rank : 200)	NC score	0.008382 (rank : 160)
Query Neighborhood Hits	223	Target Neighborhood Hits	168	Shared Neighborhood Hits	11
SwissProt Accessions	Q8N5C8, Q6VQR0	Gene names	MAP3K7IP3, TAB3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3) (NF-kappa-B-activating protein 1).

TCRG1_HUMAN
θ value	5.27518 (rank : 201)	NC score	-0.000037 (rank : 206)
Query Neighborhood Hits	223	Target Neighborhood Hits	929	Shared Neighborhood Hits	28
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

TLE1_HUMAN
θ value	5.27518 (rank : 202)	NC score	0.005243 (rank : 181)
Query Neighborhood Hits	223	Target Neighborhood Hits	485	Shared Neighborhood Hits	30
SwissProt Accessions	Q04724, Q5T3G4, Q969V9	Gene names	TLE1
Domain Architecture
Description	Transducin-like enhancer protein 1 (ESG1) (E(Sp1) homolog).

AUXI_MOUSE
θ value	6.88961 (rank : 203)	NC score	0.002351 (rank : 198)
Query Neighborhood Hits	223	Target Neighborhood Hits	114	Shared Neighborhood Hits	6
SwissProt Accessions	Q80TZ3, Q6P2K9, Q8C7L9	Gene names	Dnajc6, Kiaa0473
Domain Architecture	No domain graphic available
Description	Putative tyrosine-protein phosphatase auxilin (EC 3.1.3.48) (DnaJ homolog subfamily C member 6).

BRSK1_HUMAN
θ value	6.88961 (rank : 204)	NC score	-0.008528 (rank : 223)
Query Neighborhood Hits	223	Target Neighborhood Hits	942	Shared Neighborhood Hits	11
SwissProt Accessions	Q8TDC3, Q5J5B5, Q8NDD0, Q8NDR4, Q8TDC2, Q96AV4, Q96JL4	Gene names	BRSK1, KIAA1811, SAD1
Domain Architecture
Description	BR serine/threonine-protein kinase 1 (EC 2.7.11.1) (SAD1 kinase) (SAD1A).

CDSN_MOUSE
θ value	6.88961 (rank : 205)	NC score	0.003461 (rank : 190)
Query Neighborhood Hits	223	Target Neighborhood Hits	131	Shared Neighborhood Hits	3
SwissProt Accessions	Q7TPC1	Gene names	Cdsn
Domain Architecture	No domain graphic available
Description	Corneodesmosin precursor.

GGN_HUMAN
θ value	6.88961 (rank : 206)	NC score	0.008394 (rank : 159)
Query Neighborhood Hits	223	Target Neighborhood Hits	269	Shared Neighborhood Hits	13
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

SSXT_HUMAN
θ value	6.88961 (rank : 207)	NC score	0.007095 (rank : 169)
Query Neighborhood Hits	223	Target Neighborhood Hits	125	Shared Neighborhood Hits	12
SwissProt Accessions	Q15532, Q16404, Q9BXC6	Gene names	SS18, SSXT, SYT
Domain Architecture
Description	SSXT protein (Synovial sarcoma, translocated to X chromosome) (SYT protein).

ZCHC8_HUMAN
θ value	6.88961 (rank : 208)	NC score	0.007818 (rank : 163)
Query Neighborhood Hits	223	Target Neighborhood Hits	92	Shared Neighborhood Hits	4
SwissProt Accessions	Q6NZY4, Q7L2P6, Q8N2K5, Q96SK7, Q9NSS2, Q9NSS3	Gene names	ZCCHC8
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 8.

3BP1_HUMAN
θ value	8.99809 (rank : 209)	NC score	0.000285 (rank : 203)
Query Neighborhood Hits	223	Target Neighborhood Hits	376	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

ASPP1_HUMAN
θ value	8.99809 (rank : 210)	NC score	-0.004785 (rank : 214)
Query Neighborhood Hits	223	Target Neighborhood Hits	956	Shared Neighborhood Hits	19
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

ATX1_HUMAN
θ value	8.99809 (rank : 211)	NC score	0.003573 (rank : 189)
Query Neighborhood Hits	223	Target Neighborhood Hits	79	Shared Neighborhood Hits	6
SwissProt Accessions	P54253, Q9UJG2, Q9Y4J1	Gene names	ATXN1, ATX1, SCA1
Domain Architecture
Description	Ataxin-1 (Spinocerebellar ataxia type 1 protein).

CO4A5_HUMAN
θ value	8.99809 (rank : 212)	NC score	0.010564 (rank : 133)
Query Neighborhood Hits	223	Target Neighborhood Hits	383	Shared Neighborhood Hits	29
SwissProt Accessions	P29400, Q16006, Q16126, Q6LD84	Gene names	COL4A5
Domain Architecture
Description	Collagen alpha-5(IV) chain precursor.

COHA1_HUMAN
θ value	8.99809 (rank : 213)	NC score	0.003661 (rank : 188)
Query Neighborhood Hits	223	Target Neighborhood Hits	400	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UMD9, Q02802, Q99018, Q9NQK9, Q9UC14	Gene names	COL17A1, BP180, BPAG2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

FMNL_HUMAN
θ value	8.99809 (rank : 214)	NC score	0.004580 (rank : 184)
Query Neighborhood Hits	223	Target Neighborhood Hits	529	Shared Neighborhood Hits	21
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

GRSF1_MOUSE
θ value	8.99809 (rank : 215)	NC score	0.002806 (rank : 195)
Query Neighborhood Hits	223	Target Neighborhood Hits	60	Shared Neighborhood Hits	4
SwissProt Accessions	Q8C5Q4, Q8BR05, Q8BRG7	Gene names	Grsf1
Domain Architecture	No domain graphic available
Description	G-rich sequence factor 1 (GRSF-1).

NEK3_MOUSE
θ value	8.99809 (rank : 216)	NC score	-0.008454 (rank : 222)
Query Neighborhood Hits	223	Target Neighborhood Hits	854	Shared Neighborhood Hits	9
SwissProt Accessions	Q9R0A5, Q9Z0X9	Gene names	Nek3
Domain Architecture
Description	Serine/threonine-protein kinase Nek3 (EC 2.7.11.1) (NimA-related protein kinase 3).

PKHA6_MOUSE
θ value	8.99809 (rank : 217)	NC score	0.001385 (rank : 201)
Query Neighborhood Hits	223	Target Neighborhood Hits	591	Shared Neighborhood Hits	15
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

RSMB_HUMAN
θ value	8.99809 (rank : 218)	NC score	0.009143 (rank : 147)
Query Neighborhood Hits	223	Target Neighborhood Hits	117	Shared Neighborhood Hits	14
SwissProt Accessions	P14678, Q15490, Q9UIS5	Gene names	SNRPB, COD, SNRPB1
Domain Architecture
Description	Small nuclear ribonucleoprotein-associated proteins B and B' (snRNP-B) (Sm protein B/B') (Sm-B/Sm-B') (SmB/SmB').

RSMB_MOUSE
θ value	8.99809 (rank : 219)	NC score	0.008667 (rank : 153)
Query Neighborhood Hits	223	Target Neighborhood Hits	93	Shared Neighborhood Hits	11
SwissProt Accessions	P27048, Q3UJT1	Gene names	Snrpb
Domain Architecture
Description	Small nuclear ribonucleoprotein-associated protein B (snRNP-B) (Sm protein B) (Sm-B) (SmB).

RSMN_HUMAN
θ value	8.99809 (rank : 220)	NC score	0.009109 (rank : 148)
Query Neighborhood Hits	223	Target Neighborhood Hits	110	Shared Neighborhood Hits	15
SwissProt Accessions	P63162, P14648, P17135	Gene names	SNRPN, HCERN3, SMN
Domain Architecture	No domain graphic available
Description	Small nuclear ribonucleoprotein-associated protein N (snRNP-N) (Sm protein N) (Sm-N) (SmN) (Sm-D) (Tissue-specific-splicing protein).

RSMN_MOUSE
θ value	8.99809 (rank : 221)	NC score	0.009109 (rank : 149)
Query Neighborhood Hits	223	Target Neighborhood Hits	110	Shared Neighborhood Hits	15
SwissProt Accessions	P63163, P14648, P17135	Gene names	Snrpn, Smn
Domain Architecture	No domain graphic available
Description	Small nuclear ribonucleoprotein-associated protein N (snRNP-N) (Sm protein N) (Sm-N) (SmN) (Sm-D) (Tissue-specific-splicing protein).

SON_MOUSE
θ value	8.99809 (rank : 222)	NC score	0.008437 (rank : 157)
Query Neighborhood Hits	223	Target Neighborhood Hits	957	Shared Neighborhood Hits	60
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

ZFP28_HUMAN
θ value	8.99809 (rank : 223)	NC score	-0.007994 (rank : 221)
Query Neighborhood Hits	223	Target Neighborhood Hits	843	Shared Neighborhood Hits	13
SwissProt Accessions	Q8NHY6, Q9BY30, Q9P2B6	Gene names	ZFP28, KIAA1431
Domain Architecture
Description	Zinc finger protein 28 homolog (Zfp-28) (Krueppel-like zinc finger factor X6).

Hits sorted by NC score

RXRA_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	223	Target Neighborhood Hits	223	Shared Neighborhood Hits	223
SwissProt Accessions	P19793, Q2V504	Gene names	RXRA, NR2B1
Domain Architecture
Description	Retinoic acid receptor RXR-alpha (Retinoid X receptor alpha).

RXRA_MOUSE
NC score	0.997263 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	223	Target Neighborhood Hits	129	Shared Neighborhood Hits	122
SwissProt Accessions	P28700	Gene names	Rxra, Nr2b1
Domain Architecture
Description	Retinoic acid receptor RXR-alpha (Retinoid X receptor alpha).

RXRG_MOUSE
NC score	0.993745 (rank : 3)	θ value	2.17943e-171 (rank : 3)
Query Neighborhood Hits	223	Target Neighborhood Hits	113	Shared Neighborhood Hits	98
SwissProt Accessions	P28705	Gene names	Rxrg, Nr2b3
Domain Architecture
Description	Retinoic acid receptor RXR-gamma (Retinoid X receptor gamma).

RXRG_HUMAN
NC score	0.993744 (rank : 4)	θ value	6.34118e-171 (rank : 4)
Query Neighborhood Hits	223	Target Neighborhood Hits	114	Shared Neighborhood Hits	99
SwissProt Accessions	P48443	Gene names	RXRG, NR2B3
Domain Architecture
Description	Retinoic acid receptor RXR-gamma (Retinoid X receptor gamma).

RXRB_MOUSE
NC score	0.989598 (rank : 5)	θ value	3.37019e-164 (rank : 6)
Query Neighborhood Hits	223	Target Neighborhood Hits	230	Shared Neighborhood Hits	112
SwissProt Accessions	P28704, P33243	Gene names	Rxrb, Nr2b2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta) (MHC class I regulatory element-binding protein H-2RIIBP).

RXRB_HUMAN
NC score	0.985407 (rank : 6)	θ value	3.25673e-167 (rank : 5)
Query Neighborhood Hits	223	Target Neighborhood Hits	280	Shared Neighborhood Hits	109
SwissProt Accessions	P28702, P28703	Gene names	RXRB, NR2B2
Domain Architecture
Description	Retinoic acid receptor RXR-beta (Retinoid X receptor beta).

HNF4G_HUMAN
NC score	0.978957 (rank : 7)	θ value	7.71989e-68 (rank : 13)
Query Neighborhood Hits	223	Target Neighborhood Hits	100	Shared Neighborhood Hits	98
SwissProt Accessions	Q14541, Q9UH81, Q9UIS6	Gene names	HNF4G, NR2A2
Domain Architecture
Description	Hepatocyte nuclear factor 4-gamma (HNF-4-gamma).

HNF4G_MOUSE
NC score	0.978642 (rank : 8)	θ value	5.91091e-68 (rank : 12)
Query Neighborhood Hits	223	Target Neighborhood Hits	101	Shared Neighborhood Hits	98
SwissProt Accessions	Q9WUU6	Gene names	Hnf4g, Nr2a2
Domain Architecture
Description	Hepatocyte nuclear factor 4-gamma (HNF-4-gamma).

HNF4A_MOUSE
NC score	0.978483 (rank : 9)	θ value	2.93355e-67 (rank : 14)
Query Neighborhood Hits	223	Target Neighborhood Hits	103	Shared Neighborhood Hits	98
SwissProt Accessions	P49698	Gene names	Hnf4a, Hnf-4, Hnf4, Nr2a1, Tcf14
Domain Architecture
Description	Hepatocyte nuclear factor 4-alpha (HNF-4-alpha) (Transcription factor HNF-4) (Transcription factor 14).

HNF4A_HUMAN
NC score	0.978176 (rank : 10)	θ value	5.91091e-68 (rank : 11)
Query Neighborhood Hits	223	Target Neighborhood Hits	105	Shared Neighborhood Hits	98
SwissProt Accessions	P41235, O00659, O00723, Q14540, Q92653, Q92654, Q92655, Q99864, Q9NQH0	Gene names	HNF4A, HNF4, NR2A1, TCF14
Domain Architecture
Description	Hepatocyte nuclear factor 4-alpha (HNF-4-alpha) (Transcription factor HNF-4) (Transcription factor 14).

COT2_HUMAN
NC score	0.977225 (rank : 11)	θ value	3.23591e-74 (rank : 9)
Query Neighborhood Hits	223	Target Neighborhood Hits	135	Shared Neighborhood Hits	101
SwissProt Accessions	P24468, Q03754	Gene names	NR2F2, ARP1, TFCOUP2
Domain Architecture
Description	COUP transcription factor 2 (COUP-TF2) (COUP-TF II) (Apolipoprotein AI regulatory protein 1) (ARP-1).

COT2_MOUSE
NC score	0.977225 (rank : 12)	θ value	3.23591e-74 (rank : 10)
Query Neighborhood Hits	223	Target Neighborhood Hits	135	Shared Neighborhood Hits	101
SwissProt Accessions	P43135	Gene names	Nr2f2, Aporp1, Arp-1, Arp1, Tfcoup2
Domain Architecture
Description	COUP transcription factor 2 (COUP-TF2) (COUP-TF II) (Apolipoprotein AI regulatory protein 1) (ARP-1).

EAR2_HUMAN
NC score	0.977169 (rank : 13)	θ value	1.77973e-64 (rank : 15)
Query Neighborhood Hits	223	Target Neighborhood Hits	106	Shared Neighborhood Hits	98
SwissProt Accessions	P10588, Q9BUE8	Gene names	NR2F6, EAR2, ERBAL2
Domain Architecture
Description	Orphan nuclear receptor EAR-2 (V-erbA-related protein EAR-2).

EAR2_MOUSE
NC score	0.976331 (rank : 14)	θ value	4.38363e-63 (rank : 16)
Query Neighborhood Hits	223	Target Neighborhood Hits	104	Shared Neighborhood Hits	98
SwissProt Accessions	P43136, Q61504	Gene names	Nr2f6, Ear-2, Ear2, Erbal2
Domain Architecture
Description	Orphan nuclear receptor EAR-2 (V-erbA-related protein EAR-2).

COT1_MOUSE
NC score	0.975961 (rank : 15)	θ value	1.45253e-74 (rank : 8)
Query Neighborhood Hits	223	Target Neighborhood Hits	160	Shared Neighborhood Hits	100
SwissProt Accessions	Q60632, Q61438	Gene names	Nr2f1, Erbal3, Tfcoup1
Domain Architecture
Description	COUP transcription factor 1 (COUP-TF1) (COUP-TF I).

COT1_HUMAN
NC score	0.975643 (rank : 16)	θ value	1.45253e-74 (rank : 7)
Query Neighborhood Hits	223	Target Neighborhood Hits	159	Shared Neighborhood Hits	100
SwissProt Accessions	P10589	Gene names	NR2F1, EAR3, ERBAL3, TFCOUP1
Domain Architecture
Description	COUP transcription factor 1 (COUP-TF1) (COUP-TF I) (V-ERBA-related protein EAR-3).

NR2E3_HUMAN
NC score	0.974423 (rank : 17)	θ value	3.0428e-56 (rank : 19)
Query Neighborhood Hits	223	Target Neighborhood Hits	102	Shared Neighborhood Hits	99
SwissProt Accessions	Q9Y5X4, Q9UHM4	Gene names	NR2E3, PNR, RNR
Domain Architecture
Description	Photoreceptor-specific nuclear receptor (Retina-specific nuclear receptor).

NR2E3_MOUSE
NC score	0.973109 (rank : 18)	θ value	2.41096e-53 (rank : 21)
Query Neighborhood Hits	223	Target Neighborhood Hits	113	Shared Neighborhood Hits	98
SwissProt Accessions	Q9QXZ7	Gene names	Nr2e3, Pnr, Rnr
Domain Architecture
Description	Photoreceptor-specific nuclear receptor (Retina-specific nuclear receptor).

NR2E1_MOUSE
NC score	0.971260 (rank : 19)	θ value	2.94719e-51 (rank : 25)
Query Neighborhood Hits	223	Target Neighborhood Hits	106	Shared Neighborhood Hits	100
SwissProt Accessions	Q64104	Gene names	Nr2e1, Tll, Tlx
Domain Architecture
Description	Orphan nuclear receptor NR2E1 (Nuclear receptor TLX) (Tailless homolog) (Tll) (mTll).

NR2E1_HUMAN
NC score	0.969233 (rank : 20)	θ value	1.91031e-50 (rank : 26)
Query Neighborhood Hits	223	Target Neighborhood Hits	103	Shared Neighborhood Hits	98
SwissProt Accessions	Q9Y466	Gene names	NR2E1, TLX
Domain Architecture
Description	Orphan nuclear receptor NR2E1 (Nuclear receptor TLX) (Tailless homolog) (Tll) (hTll).

ERR3_HUMAN
NC score	0.961832 (rank : 21)	θ value	1.36585e-56 (rank : 17)
Query Neighborhood Hits	223	Target Neighborhood Hits	106	Shared Neighborhood Hits	98
SwissProt Accessions	P62508, O75454, O96021, Q68DA0, Q6P274, Q6PK28, Q6TS38, Q9R1F3, Q9UNJ4	Gene names	ESRRG, ERR3, ERRG2, KIAA0832, NR3B3
Domain Architecture	No domain graphic available
Description	Estrogen-related receptor gamma (Estrogen receptor-related protein 3) (ERR gamma-2).

ERR3_MOUSE
NC score	0.961832 (rank : 22)	θ value	1.36585e-56 (rank : 18)
Query Neighborhood Hits	223	Target Neighborhood Hits	106	Shared Neighborhood Hits	98
SwissProt Accessions	P62509, O75454, O96021, Q8CHC9, Q9R1F3	Gene names	Esrrg, Err3, Kiaa0832, Nr3b3
Domain Architecture	No domain graphic available
Description	Estrogen-related receptor gamma (Estrogen receptor-related protein 3).

ERR2_MOUSE
NC score	0.960913 (rank : 23)	θ value	6.34462e-54 (rank : 20)
Query Neighborhood Hits	223	Target Neighborhood Hits	109	Shared Neighborhood Hits	99
SwissProt Accessions	Q61539, O09067, O09146	Gene names	Esrrb, Err-2, Err2, Nr3b2
Domain Architecture
Description	Steroid hormone receptor ERR2 (Estrogen-related receptor, beta) (ERR- beta) (Estrogen receptor-like 2).

ERR2_HUMAN
NC score	0.958519 (rank : 24)	θ value	1.01294e-51 (rank : 24)
Query Neighborhood Hits	223	Target Neighborhood Hits	108	Shared Neighborhood Hits	99
SwissProt Accessions	O95718, Q9HCB4	Gene names	ESRRB, ERRB2, NR3B2
Domain Architecture
Description	Steroid hormone receptor ERR2 (Estrogen-related receptor, beta) (ERR- beta) (Estrogen receptor-like 2) (ERR beta-2).

ERR1_HUMAN
NC score	0.956389 (rank : 25)	θ value	1.19932e-44 (rank : 35)
Query Neighborhood Hits	223	Target Neighborhood Hits	157	Shared Neighborhood Hits	104
SwissProt Accessions	P11474, Q14514	Gene names	ESRRA, ERR1, ESRL1, NR3B1
Domain Architecture
Description	Steroid hormone receptor ERR1 (Estrogen-related receptor, alpha) (ERR- alpha) (Estrogen receptor-like 1).

RARB_HUMAN
NC score	0.948331 (rank : 26)	θ value	2.66562e-52 (rank : 22)
Query Neighborhood Hits	223	Target Neighborhood Hits	118	Shared Neighborhood Hits	94
SwissProt Accessions	P10826, P12891, Q00989, Q15298, Q9UN48	Gene names	RARB, HAP, NR1B2
Domain Architecture
Description	Retinoic acid receptor beta (RAR-beta) (RAR-epsilon) (HBV-activated protein).

RARB_MOUSE
NC score	0.948245 (rank : 27)	θ value	2.66562e-52 (rank : 23)
Query Neighborhood Hits	223	Target Neighborhood Hits	109	Shared Neighborhood Hits	95
SwissProt Accessions	P22605, P11417, P22604	Gene names	Rarb, Nr1b2
Domain Architecture
Description	Retinoic acid receptor beta (RAR-beta).

RARA_MOUSE
NC score	0.948026 (rank : 28)	θ value	1.23823e-49 (rank : 28)
Query Neighborhood Hits	223	Target Neighborhood Hits	113	Shared Neighborhood Hits	96
SwissProt Accessions	P11416, P22603	Gene names	Rara, Nr1b1
Domain Architecture
Description	Retinoic acid receptor alpha (RAR-alpha).

RARA_HUMAN
NC score	0.947893 (rank : 29)	θ value	1.23823e-49 (rank : 27)
Query Neighborhood Hits	223	Target Neighborhood Hits	118	Shared Neighborhood Hits	96
SwissProt Accessions	P10276, P78456, Q13440, Q13441, Q9NQS0	Gene names	RARA, NR1B1
Domain Architecture
Description	Retinoic acid receptor alpha (RAR-alpha).

RARG2_HUMAN
NC score	0.947163 (rank : 30)	θ value	1.36902e-48 (rank : 32)
Query Neighborhood Hits	223	Target Neighborhood Hits	109	Shared Neighborhood Hits	95
SwissProt Accessions	P22932, Q15281	Gene names	RARG, NR1B3
Domain Architecture	No domain graphic available
Description	Retinoic acid receptor gamma-2 (RAR-gamma-2).

RARG2_MOUSE
NC score	0.947017 (rank : 31)	θ value	2.1121e-49 (rank : 30)
Query Neighborhood Hits	223	Target Neighborhood Hits	114	Shared Neighborhood Hits	96
SwissProt Accessions	P20787	Gene names	Rarg, Nr1b3
Domain Architecture
Description	Retinoic acid receptor gamma-B (RAR-gamma-B).

RARG1_HUMAN
NC score	0.947008 (rank : 32)	θ value	1.36902e-48 (rank : 31)
Query Neighborhood Hits	223	Target Neighborhood Hits	107	Shared Neighborhood Hits	95
SwissProt Accessions	P13631	Gene names	RARG, NR1B3
Domain Architecture
Description	Retinoic acid receptor gamma-1 (RAR-gamma-1).

RARG1_MOUSE
NC score	0.946718 (rank : 33)	θ value	2.1121e-49 (rank : 29)
Query Neighborhood Hits	223	Target Neighborhood Hits	113	Shared Neighborhood Hits	96
SwissProt Accessions	P18911, Q91VK5	Gene names	Rarg, Nr1b3
Domain Architecture
Description	Retinoic acid receptor gamma-A (RAR-gamma-A).

NR4A2_MOUSE
NC score	0.944865 (rank : 34)	θ value	1.41672e-45 (rank : 34)
Query Neighborhood Hits	223	Target Neighborhood Hits	121	Shared Neighborhood Hits	96
SwissProt Accessions	Q06219, O08690	Gene names	Nr4a2, Nurr1
Domain Architecture
Description	Orphan nuclear receptor NR4A2 (Orphan nuclear receptor NURR1) (NUR- related factor 1).

NR4A2_HUMAN
NC score	0.944823 (rank : 35)	θ value	1.41672e-45 (rank : 33)
Query Neighborhood Hits	223	Target Neighborhood Hits	120	Shared Neighborhood Hits	96
SwissProt Accessions	P43354, Q16311	Gene names	NR4A2, NOT, NURR1, TINUR
Domain Architecture
Description	Orphan nuclear receptor NR4A2 (Orphan nuclear receptor NURR1) (Immediate-early response protein NOT) (Transcriptionally-inducible nuclear receptor).

NR4A3_MOUSE
NC score	0.943911 (rank : 36)	θ value	6.15952e-41 (rank : 36)
Query Neighborhood Hits	223	Target Neighborhood Hits	127	Shared Neighborhood Hits	95
SwissProt Accessions	Q9QZB6, Q9QZB5	Gene names	Nr4a3, Tec
Domain Architecture
Description	Orphan nuclear receptor NR4A3 (Orphan nuclear receptor TEC) (Translocated in extraskeletal chondrosarcoma).

NR4A3_HUMAN
NC score	0.943056 (rank : 37)	θ value	8.89434e-40 (rank : 37)
Query Neighborhood Hits	223	Target Neighborhood Hits	131	Shared Neighborhood Hits	95
SwissProt Accessions	Q92570, Q12935, Q14979, Q16420, Q4VXA9, Q9UEK2, Q9UEK3	Gene names	NR4A3, CHN, CSMF, MINOR, NOR1, TEC
Domain Architecture
Description	Orphan nuclear receptor NR4A3 (Nuclear hormone receptor NOR-1) (Neuron-derived orphan receptor 1) (Mitogen-induced nuclear orphan receptor).

NR4A1_HUMAN
NC score	0.941729 (rank : 38)	θ value	2.05049e-36 (rank : 42)
Query Neighborhood Hits	223	Target Neighborhood Hits	133	Shared Neighborhood Hits	98
SwissProt Accessions	P22736	Gene names	NR4A1, GFRP1, HMR, NAK1
Domain Architecture
Description	Orphan nuclear receptor NR4A1 (Orphan nuclear receptor HMR) (Early response protein NAK1) (TR3 orphan receptor) (ST-59).

ESR2_HUMAN
NC score	0.941071 (rank : 39)	θ value	4.41421e-39 (rank : 39)
Query Neighborhood Hits	223	Target Neighborhood Hits	110	Shared Neighborhood Hits	98
SwissProt Accessions	Q92731, O60608, O60685, O60702, O60703, O75583, O75584, Q86Z31, Q9UEV6, Q9UHD3, Q9UQK9	Gene names	ESR2, ESTRB, NR3A2
Domain Architecture
Description	Estrogen receptor beta (ER-beta).

NR4A1_MOUSE
NC score	0.940157 (rank : 40)	θ value	1.01765e-35 (rank : 46)
Query Neighborhood Hits	223	Target Neighborhood Hits	128	Shared Neighborhood Hits	98
SwissProt Accessions	P12813	Gene names	Nr4a1, Gfrp, Hmr, N10, Nur77
Domain Architecture
Description	Orphan nuclear receptor NR4A1 (Orphan nuclear receptor HMR) (Nuclear hormone receptor NUR/77) (N10 nuclear protein).

ESR2_MOUSE
NC score	0.939405 (rank : 41)	θ value	1.98146e-39 (rank : 38)
Query Neighborhood Hits	223	Target Neighborhood Hits	110	Shared Neighborhood Hits	96
SwissProt Accessions	O08537, O35635, O70519	Gene names	Esr2, Estrb, Nr3a2
Domain Architecture
Description	Estrogen receptor beta (ER-beta).

ESR1_MOUSE
NC score	0.934831 (rank : 42)	θ value	5.584e-34 (rank : 48)
Query Neighborhood Hits	223	Target Neighborhood Hits	104	Shared Neighborhood Hits	95
SwissProt Accessions	P19785, Q9JJT5, Q9QY51, Q9QY52	Gene names	Esr1, Esr, Estr, Estra, Nr3a1
Domain Architecture
Description	Estrogen receptor (ER) (Estradiol receptor) (ER-alpha).

ESR1_HUMAN
NC score	0.934789 (rank : 43)	θ value	1.46948e-34 (rank : 47)
Query Neighborhood Hits	223	Target Neighborhood Hits	105	Shared Neighborhood Hits	95
SwissProt Accessions	P03372, Q13511, Q14276, Q9NU51, Q9UDZ7, Q9UIS7	Gene names	ESR1, ESR, NR3A1
Domain Architecture
Description	Estrogen receptor (ER) (Estradiol receptor) (ER-alpha).

NR1H3_HUMAN
NC score	0.932897 (rank : 44)	θ value	2.12192e-33 (rank : 50)
Query Neighborhood Hits	223	Target Neighborhood Hits	104	Shared Neighborhood Hits	95
SwissProt Accessions	Q13133, Q96H87	Gene names	NR1H3, LXRA
Domain Architecture
Description	Oxysterols receptor LXR-alpha (Liver X receptor alpha) (Nuclear orphan receptor LXR-alpha).

NR1H4_HUMAN
NC score	0.932774 (rank : 45)	θ value	8.91499e-32 (rank : 58)
Query Neighborhood Hits	223	Target Neighborhood Hits	112	Shared Neighborhood Hits	97
SwissProt Accessions	Q96RI1, Q8NFP5, Q8NFP6, Q92943	Gene names	NR1H4, BAR, FXR, HRR1, RIP14
Domain Architecture
Description	Bile acid receptor (Farnesoid X-activated receptor) (Farnesol receptor HRR-1) (Retinoid X receptor-interacting protein 14) (RXR-interacting protein 14).

NR1H3_MOUSE
NC score	0.932212 (rank : 46)	θ value	1.0531e-32 (rank : 57)
Query Neighborhood Hits	223	Target Neighborhood Hits	102	Shared Neighborhood Hits	94
SwissProt Accessions	Q9Z0Y9, Q9QUH7	Gene names	Nr1h3, Lxra
Domain Architecture
Description	Oxysterols receptor LXR-alpha (Liver X receptor alpha) (Nuclear orphan receptor LXR-alpha).

NR1H4_MOUSE
NC score	0.932150 (rank : 47)	θ value	1.98606e-31 (rank : 59)
Query Neighborhood Hits	223	Target Neighborhood Hits	113	Shared Neighborhood Hits	97
SwissProt Accessions	Q60641, Q60642, Q60643	Gene names	Nr1h4, Bar, Fxr, Rip14
Domain Architecture
Description	Bile acid receptor (Farnesoid X-activated receptor) (Farnesol receptor HRR-1) (Retinoid X receptor-interacting protein 14) (RXR-interacting protein 14).

NR6A1_HUMAN
NC score	0.930766 (rank : 48)	θ value	2.35151e-24 (rank : 81)
Query Neighborhood Hits	223	Target Neighborhood Hits	108	Shared Neighborhood Hits	98
SwissProt Accessions	Q15406, O00551, O00603, Q8NHQ0, Q92898, Q99802	Gene names	NR6A1, GCNF
Domain Architecture
Description	Orphan nuclear receptor NR6A1 (Germ cell nuclear factor) (GCNF) (Retinoid receptor-related testis-specific receptor) (RTR).

TR2_HUMAN
NC score	0.930284 (rank : 49)	θ value	2.42779e-29 (rank : 65)
Query Neighborhood Hits	223	Target Neighborhood Hits	110	Shared Neighborhood Hits	97
SwissProt Accessions	P13056	Gene names	NR2C1, TR2
Domain Architecture
Description	Orphan nuclear receptor TR2 (Testicular receptor 2).

NR6A1_MOUSE
NC score	0.930064 (rank : 50)	θ value	2.35151e-24 (rank : 82)
Query Neighborhood Hits	223	Target Neighborhood Hits	110	Shared Neighborhood Hits	98
SwissProt Accessions	Q64249	Gene names	Nr6a1, Gcnf
Domain Architecture
Description	Orphan nuclear receptor NR6A1 (Germ cell nuclear factor) (GCNF) (Retinoid receptor-related testis-specific receptor) (RTR).

NR1I3_HUMAN
NC score	0.930007 (rank : 51)	θ value	1.37858e-24 (rank : 79)
Query Neighborhood Hits	223	Target Neighborhood Hits	107	Shared Neighborhood Hits	98
SwissProt Accessions	Q14994	Gene names	NR1I3, CAR
Domain Architecture
Description	Orphan nuclear receptor NR1I3 (Constitutive androstane receptor) (CAR) (Constitutive activator of retinoid response) (Constitutive active response) (Orphan nuclear receptor MB67).

THA_HUMAN
NC score	0.927946 (rank : 52)	θ value	3.73686e-38 (rank : 40)
Query Neighborhood Hits	223	Target Neighborhood Hits	113	Shared Neighborhood Hits	97
SwissProt Accessions	P10827, P21205, Q8N6A1, Q96H73	Gene names	THRA, ERBA1, NR1A1, THRA1
Domain Architecture
Description	Thyroid hormone receptor alpha (C-erbA-alpha) (c-erbA-1) (EAR-7) (EAR7).

THA_MOUSE
NC score	0.927919 (rank : 53)	θ value	3.73686e-38 (rank : 41)
Query Neighborhood Hits	223	Target Neighborhood Hits	113	Shared Neighborhood Hits	97
SwissProt Accessions	P63058, P10685, P15827, P16416, P37241, Q63107, Q63195, Q63196, Q99146	Gene names	Thra, C-erba-alpha, Nr1a1
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor alpha (C-erbA-alpha) (c-erbA-1).

TR2_MOUSE
NC score	0.926812 (rank : 54)	θ value	1.4233e-29 (rank : 64)
Query Neighborhood Hits	223	Target Neighborhood Hits	100	Shared Neighborhood Hits	98
SwissProt Accessions	Q505F1, P97763, Q3UIJ7, Q4U1Z4, Q60927, Q62152, Q8VIJ3	Gene names	Nr2c1, Tr2, Tr2-11
Domain Architecture	No domain graphic available
Description	Orphan nuclear receptor TR2 (Testicular receptor 2) (mTR2).

TR4_HUMAN
NC score	0.926725 (rank : 55)	θ value	2.59387e-31 (rank : 61)
Query Neighborhood Hits	223	Target Neighborhood Hits	117	Shared Neighborhood Hits	100
SwissProt Accessions	P49116, P55092	Gene names	NR2C2, TAK1, TR4
Domain Architecture
Description	Orphan nuclear receptor TR4 (Orphan nuclear receptor TAK1).

PPARA_HUMAN
NC score	0.926568 (rank : 56)	θ value	5.96599e-36 (rank : 45)
Query Neighborhood Hits	223	Target Neighborhood Hits	100	Shared Neighborhood Hits	94
SwissProt Accessions	Q07869, Q16241, Q92486, Q92689, Q9Y3N1	Gene names	PPARA, NR1C1, PPAR
Domain Architecture
Description	Peroxisome proliferator-activated receptor alpha (PPAR-alpha).

TR4_MOUSE
NC score	0.926006 (rank : 57)	θ value	1.6813e-30 (rank : 63)
Query Neighborhood Hits	223	Target Neighborhood Hits	115	Shared Neighborhood Hits	99
SwissProt Accessions	P49117, P55093	Gene names	Nr2c2, Mtr2r1, Tak1, Tr4
Domain Architecture
Description	Orphan nuclear receptor TR4 (Orphan nuclear receptor TAK1).

NR1I3_MOUSE
NC score	0.925632 (rank : 58)	θ value	2.35151e-24 (rank : 80)
Query Neighborhood Hits	223	Target Neighborhood Hits	103	Shared Neighborhood Hits	98
SwissProt Accessions	O35627, O35628	Gene names	Nr1i3, Car
Domain Architecture
Description	Orphan nuclear receptor NR1I3 (Constitutive androstane receptor) (CAR) (Orphan nuclear receptor MB67).

PPARA_MOUSE
NC score	0.925383 (rank : 59)	θ value	2.12192e-33 (rank : 51)
Query Neighborhood Hits	223	Target Neighborhood Hits	99	Shared Neighborhood Hits	95
SwissProt Accessions	P23204	Gene names	Ppara, Nr1c1, Ppar
Domain Architecture
Description	Peroxisome proliferator-activated receptor alpha (PPAR-alpha).

NR5A2_MOUSE
NC score	0.924352 (rank : 60)	θ value	9.8567e-31 (rank : 62)
Query Neighborhood Hits	223	Target Neighborhood Hits	107	Shared Neighborhood Hits	98
SwissProt Accessions	P45448	Gene names	Nr5a2, Lrh1
Domain Architecture
Description	Orphan nuclear receptor NR5A2 (Liver receptor homolog 1) (LRH-1).

PPARD_HUMAN
NC score	0.922839 (rank : 61)	θ value	3.4976e-36 (rank : 44)
Query Neighborhood Hits	223	Target Neighborhood Hits	102	Shared Neighborhood Hits	94
SwissProt Accessions	Q03181, Q7Z5K0, Q9BUD4	Gene names	PPARD, NR1C2, PPARB
Domain Architecture
Description	Peroxisome proliferator-activated receptor delta (PPAR-delta) (PPAR- beta) (Nuclear hormone receptor 1) (NUC1) (NUCI).

NR5A2_HUMAN
NC score	0.922528 (rank : 62)	θ value	1.98606e-31 (rank : 60)
Query Neighborhood Hits	223	Target Neighborhood Hits	112	Shared Neighborhood Hits	99
SwissProt Accessions	O00482, O95642	Gene names	NR5A2, B1F, CPF, FTF
Domain Architecture
Description	Orphan nuclear receptor NR5A2 (Alpha-1-fetoprotein transcription factor) (Hepatocytic transcription factor) (B1-binding factor) (hB1F) (CYP7A promoter-binding factor) (Liver receptor homolog 1) (LRH-1).

THB2_HUMAN
NC score	0.922106 (rank : 63)	θ value	2.77131e-33 (rank : 54)
Query Neighborhood Hits	223	Target Neighborhood Hits	104	Shared Neighborhood Hits	98
SwissProt Accessions	P37243	Gene names	THRB, ERBA2, NR1A2, THR1
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor beta-2.

STF1_MOUSE
NC score	0.921769 (rank : 64)	θ value	8.08199e-25 (rank : 76)
Query Neighborhood Hits	223	Target Neighborhood Hits	137	Shared Neighborhood Hits	99
SwissProt Accessions	P33242	Gene names	Nr5a1, Ftzf1
Domain Architecture
Description	Steroidogenic factor 1 (STF-1) (SF-1) (Adrenal 4-binding protein) (Steroid hormone receptor Ad4BP) (Fushi tarazu factor homolog 1) (Embryonal LTR-binding protein) (ELP) (Embryonal long terminal repeat- binding protein) (Steroid hydroxylase positive regulator).

THB1_HUMAN
NC score	0.921651 (rank : 65)	θ value	1.6247e-33 (rank : 49)
Query Neighborhood Hits	223	Target Neighborhood Hits	106	Shared Neighborhood Hits	98
SwissProt Accessions	P10828, Q13986	Gene names	THRB, ERBA2, NR1A2, THR1
Domain Architecture
Description	Thyroid hormone receptor beta-1.

PPARD_MOUSE
NC score	0.921085 (rank : 66)	θ value	2.67802e-36 (rank : 43)
Query Neighborhood Hits	223	Target Neighborhood Hits	103	Shared Neighborhood Hits	94
SwissProt Accessions	P35396, P37239	Gene names	Ppard, Nr1c2, Pparb
Domain Architecture
Description	Peroxisome proliferator-activated receptor delta (PPAR-delta) (PPAR- beta) (Nuclear hormone receptor 1) (NUC1).

THB2_MOUSE
NC score	0.920781 (rank : 67)	θ value	2.12192e-33 (rank : 53)
Query Neighborhood Hits	223	Target Neighborhood Hits	106	Shared Neighborhood Hits	98
SwissProt Accessions	P37244	Gene names	Thrb, C-erba-beta, Nr1a2
Domain Architecture
Description	Thyroid hormone receptor beta-2.

THB1_MOUSE
NC score	0.920754 (rank : 68)	θ value	2.12192e-33 (rank : 52)
Query Neighborhood Hits	223	Target Neighborhood Hits	105	Shared Neighborhood Hits	98
SwissProt Accessions	P37242	Gene names	Thrb, C-erba-beta, Nr1a2
Domain Architecture
Description	Thyroid hormone receptor beta-1.

NR1H2_MOUSE
NC score	0.920736 (rank : 69)	θ value	5.40856e-29 (rank : 67)
Query Neighborhood Hits	223	Target Neighborhood Hits	109	Shared Neighborhood Hits	97
SwissProt Accessions	Q60644	Gene names	Nr1h2, Lxrb, Rip15, Unr, Unr2
Domain Architecture
Description	Oxysterols receptor LXR-beta (Liver X receptor beta) (Nuclear orphan receptor LXR-beta) (Ubiquitously-expressed nuclear receptor) (Retinoid X receptor-interacting protein No.15).

PPARG_HUMAN
NC score	0.920594 (rank : 70)	θ value	3.61944e-33 (rank : 55)
Query Neighborhood Hits	223	Target Neighborhood Hits	97	Shared Neighborhood Hits	94
SwissProt Accessions	P37231, O00684, O00710, O14515, Q15178, Q15179, Q15180, Q15832, Q86U60, Q96J12	Gene names	PPARG, NR1C3
Domain Architecture
Description	Peroxisome proliferator-activated receptor gamma (PPAR-gamma).

PPARG_MOUSE
NC score	0.920163 (rank : 71)	θ value	8.06329e-33 (rank : 56)
Query Neighborhood Hits	223	Target Neighborhood Hits	97	Shared Neighborhood Hits	94
SwissProt Accessions	P37238	Gene names	Pparg, Nr1c3
Domain Architecture
Description	Peroxisome proliferator-activated receptor gamma (PPAR-gamma).

STF1_HUMAN
NC score	0.919612 (rank : 72)	θ value	8.08199e-25 (rank : 75)
Query Neighborhood Hits	223	Target Neighborhood Hits	132	Shared Neighborhood Hits	99
SwissProt Accessions	Q13285, O15196	Gene names	NR5A1, AD4BP, FTZF1, SF1
Domain Architecture
Description	Steroidogenic factor 1 (STF-1) (SF-1) (Adrenal 4-binding protein) (Steroid hormone receptor Ad4BP) (Fushi tarazu factor homolog 1).

NR1D1_HUMAN
NC score	0.914935 (rank : 73)	θ value	1.42661e-21 (rank : 92)
Query Neighborhood Hits	223	Target Neighborhood Hits	140	Shared Neighborhood Hits	96
SwissProt Accessions	P20393, Q15304	Gene names	NR1D1, EAR1, HREV, THRAL
Domain Architecture
Description	Orphan nuclear receptor NR1D1 (V-erbA-related protein EAR-1) (Rev- erbA-alpha).

NR1H2_HUMAN
NC score	0.914619 (rank : 74)	θ value	5.40856e-29 (rank : 66)
Query Neighborhood Hits	223	Target Neighborhood Hits	114	Shared Neighborhood Hits	96
SwissProt Accessions	P55055, Q12970	Gene names	NR1H2, LXRB, NER, UNR
Domain Architecture
Description	Oxysterols receptor LXR-beta (Liver X receptor beta) (Nuclear orphan receptor LXR-beta) (Ubiquitously-expressed nuclear receptor) (Nuclear receptor NER).

PXR_MOUSE
NC score	0.909829 (rank : 75)	θ value	2.12685e-25 (rank : 70)
Query Neighborhood Hits	223	Target Neighborhood Hits	107	Shared Neighborhood Hits	97
SwissProt Accessions	O54915	Gene names	Nr1i2, Pxr
Domain Architecture
Description	Orphan nuclear receptor PXR (Pregnane X receptor).

NR1D2_HUMAN
NC score	0.908373 (rank : 76)	θ value	9.87957e-23 (rank : 88)
Query Neighborhood Hits	223	Target Neighborhood Hits	115	Shared Neighborhood Hits	94
SwissProt Accessions	Q14995, O00402, Q86XD4	Gene names	NR1D2
Domain Architecture
Description	Orphan nuclear receptor NR1D2 (Rev-erb-beta) (EAR-1R) (Orphan nuclear hormone receptor BD73).

PXR_HUMAN
NC score	0.907300 (rank : 77)	θ value	4.01107e-24 (rank : 84)
Query Neighborhood Hits	223	Target Neighborhood Hits	107	Shared Neighborhood Hits	97
SwissProt Accessions	O75469, Q96AC7, Q9UJ22, Q9UJ23, Q9UJ24, Q9UJ25, Q9UJ26, Q9UJ27	Gene names	NR1I2, PXR
Domain Architecture
Description	Orphan nuclear receptor PXR (Pregnane X receptor) (Orphan nuclear receptor PAR1) (Steroid and xenobiotic receptor) (SXR).

VDR_MOUSE
NC score	0.906699 (rank : 78)	θ value	1.47631e-18 (rank : 93)
Query Neighborhood Hits	223	Target Neighborhood Hits	103	Shared Neighborhood Hits	96
SwissProt Accessions	P48281	Gene names	Vdr, Nr1i1
Domain Architecture
Description	Vitamin D3 receptor (VDR) (1,25-dihydroxyvitamin D3 receptor).

VDR_HUMAN
NC score	0.906576 (rank : 79)	θ value	1.92812e-18 (rank : 94)
Query Neighborhood Hits	223	Target Neighborhood Hits	112	Shared Neighborhood Hits	96
SwissProt Accessions	P11473	Gene names	VDR, NR1I1
Domain Architecture
Description	Vitamin D3 receptor (VDR) (1,25-dihydroxyvitamin D3 receptor).

NR1D2_MOUSE
NC score	0.905771 (rank : 80)	θ value	2.20094e-22 (rank : 90)
Query Neighborhood Hits	223	Target Neighborhood Hits	109	Shared Neighborhood Hits	94
SwissProt Accessions	Q60674, Q60646	Gene names	Nr1d2
Domain Architecture
Description	Orphan nuclear receptor NR1D2 (Rev-erb-beta) (Orphan nuclear receptor RVR).

RORG_MOUSE
NC score	0.902431 (rank : 81)	θ value	1.16704e-23 (rank : 86)
Query Neighborhood Hits	223	Target Neighborhood Hits	107	Shared Neighborhood Hits	95
SwissProt Accessions	P51450, Q61027, Q91YT5, Q9QXD9, Q9R177	Gene names	Rorc, Nr1f3, Rorg, Thor
Domain Architecture
Description	Nuclear receptor ROR-gamma (Nuclear receptor RZR-gamma) (Thymus orphan receptor) (TOR).

RORB_MOUSE
NC score	0.900532 (rank : 82)	θ value	1.05554e-24 (rank : 78)
Query Neighborhood Hits	223	Target Neighborhood Hits	99	Shared Neighborhood Hits	94
SwissProt Accessions	Q8R1B8	Gene names	Rorb, Nr1f2
Domain Architecture
Description	Nuclear receptor ROR-beta (Nuclear receptor RZR-beta).

RORB_HUMAN
NC score	0.900520 (rank : 83)	θ value	1.05554e-24 (rank : 77)
Query Neighborhood Hits	223	Target Neighborhood Hits	99	Shared Neighborhood Hits	94
SwissProt Accessions	Q92753, Q8WX73	Gene names	RORB, NR1F2, RZRB
Domain Architecture
Description	Nuclear receptor ROR-beta (Nuclear receptor RZR-beta).

RORA_HUMAN
NC score	0.900413 (rank : 84)	θ value	2.12685e-25 (rank : 71)
Query Neighborhood Hits	223	Target Neighborhood Hits	105	Shared Neighborhood Hits	94
SwissProt Accessions	P35398, P35397, P35399, P45445, Q96H83	Gene names	RORA, NR1F1, RZRA
Domain Architecture
Description	Nuclear receptor ROR-alpha (Nuclear receptor RZR-alpha).

RORA_MOUSE
NC score	0.899846 (rank : 85)	θ value	2.12685e-25 (rank : 72)
Query Neighborhood Hits	223	Target Neighborhood Hits	105	Shared Neighborhood Hits	94
SwissProt Accessions	P51448, P70283, P97741, P97773, Q923G1	Gene names	Rora, Nr1f1, Rzra
Domain Architecture
Description	Nuclear receptor ROR-alpha (Nuclear receptor RZR-alpha).

RORG_HUMAN
NC score	0.898999 (rank : 86)	θ value	4.01107e-24 (rank : 85)
Query Neighborhood Hits	223	Target Neighborhood Hits	119	Shared Neighborhood Hits	95
SwissProt Accessions	P51449, Q8N5V7, Q8NCY8	Gene names	RORC, NR1F3, RORG, RZRG
Domain Architecture
Description	Nuclear receptor ROR-gamma (Nuclear receptor RZR-gamma).

GCR_HUMAN
NC score	0.885240 (rank : 87)	θ value	1.62847e-25 (rank : 69)
Query Neighborhood Hits	223	Target Neighborhood Hits	113	Shared Neighborhood Hits	94
SwissProt Accessions	P04150, P04151, Q53EP5, Q6N0A4	Gene names	NR3C1, GRL
Domain Architecture
Description	Glucocorticoid receptor (GR).

ANDR_MOUSE
NC score	0.883451 (rank : 88)	θ value	5.59698e-26 (rank : 68)
Query Neighborhood Hits	223	Target Neighborhood Hits	133	Shared Neighborhood Hits	95
SwissProt Accessions	P19091	Gene names	Ar, Nr3c4
Domain Architecture
Description	Androgen receptor (Dihydrotestosterone receptor).

ANDR_HUMAN
NC score	0.881044 (rank : 89)	θ value	1.29031e-22 (rank : 89)
Query Neighborhood Hits	223	Target Neighborhood Hits	126	Shared Neighborhood Hits	97
SwissProt Accessions	P10275	Gene names	AR, DHTR, NR3C4
Domain Architecture
Description	Androgen receptor (Dihydrotestosterone receptor).

GCR_MOUSE
NC score	0.879325 (rank : 90)	θ value	8.08199e-25 (rank : 74)
Query Neighborhood Hits	223	Target Neighborhood Hits	117	Shared Neighborhood Hits	94
SwissProt Accessions	P06537, Q61628, Q61629	Gene names	Nr3c1, Grl, Grl1
Domain Architecture
Description	Glucocorticoid receptor (GR).

MCR_HUMAN
NC score	0.877950 (rank : 91)	θ value	2.59989e-23 (rank : 87)
Query Neighborhood Hits	223	Target Neighborhood Hits	149	Shared Neighborhood Hits	100
SwissProt Accessions	P08235, Q96KQ8, Q96KQ9	Gene names	NR3C2, MCR, MLR
Domain Architecture
Description	Mineralocorticoid receptor (MR).

PRGR_HUMAN
NC score	0.874716 (rank : 92)	θ value	2.35151e-24 (rank : 83)
Query Neighborhood Hits	223	Target Neighborhood Hits	163	Shared Neighborhood Hits	98
SwissProt Accessions	P06401, Q9UPF7	Gene names	PGR, NR3C3
Domain Architecture
Description	Progesterone receptor (PR).

MCR_MOUSE
NC score	0.873523 (rank : 93)	θ value	8.36355e-22 (rank : 91)
Query Neighborhood Hits	223	Target Neighborhood Hits	162	Shared Neighborhood Hits	102
SwissProt Accessions	Q8VII8, Q8VII9	Gene names	Nr3c2, Mlr
Domain Architecture	No domain graphic available
Description	Mineralocorticoid receptor (MR).

PRGR_MOUSE
NC score	0.870063 (rank : 94)	θ value	4.73814e-25 (rank : 73)
Query Neighborhood Hits	223	Target Neighborhood Hits	286	Shared Neighborhood Hits	105
SwissProt Accessions	Q00175	Gene names	Pgr, Nr3c3, Pr
Domain Architecture
Description	Progesterone receptor (PR).

SHP_HUMAN
NC score	0.597473 (rank : 95)	θ value	8.67504e-11 (rank : 95)
Query Neighborhood Hits	223	Target Neighborhood Hits	57	Shared Neighborhood Hits	56
SwissProt Accessions	Q15466, Q5QP36	Gene names	NR0B2, SHP
Domain Architecture
Description	Nuclear receptor 0B2 (Orphan nuclear receptor SHP) (Small heterodimer partner).

SHP_MOUSE
NC score	0.586770 (rank : 96)	θ value	2.52405e-10 (rank : 97)
Query Neighborhood Hits	223	Target Neighborhood Hits	53	Shared Neighborhood Hits	53
SwissProt Accessions	Q62227, Q53Z53	Gene names	Nr0b2, Shp
Domain Architecture
Description	Nuclear receptor 0B2 (Orphan nuclear receptor SHP) (Small heterodimer partner).

DAX1_MOUSE
NC score	0.578905 (rank : 97)	θ value	4.30538e-10 (rank : 98)
Query Neighborhood Hits	223	Target Neighborhood Hits	70	Shared Neighborhood Hits	60
SwissProt Accessions	Q61066, O09068, O09147	Gene names	Nr0b1, Ahch, Dax1
Domain Architecture
Description	Nuclear receptor 0B1 (Nuclear receptor DAX-1).

DAX1_HUMAN
NC score	0.556164 (rank : 98)	θ value	1.47974e-10 (rank : 96)
Query Neighborhood Hits	223	Target Neighborhood Hits	65	Shared Neighborhood Hits	59
SwissProt Accessions	P51843, Q96F69	Gene names	NR0B1, AHC, DAX1
Domain Architecture
Description	Nuclear receptor 0B1 (Nuclear receptor DAX-1) (DSS-AHC critical region on the X chromosome protein 1).

BCL9_MOUSE
NC score	0.055818 (rank : 99)	θ value	0.00298849 (rank : 100)
Query Neighborhood Hits	223	Target Neighborhood Hits	770	Shared Neighborhood Hits	68
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

BCL9_HUMAN
NC score	0.050681 (rank : 100)	θ value	0.00228821 (rank : 99)
Query Neighborhood Hits	223	Target Neighborhood Hits	1008	Shared Neighborhood Hits	83
SwissProt Accessions	O00512	Gene names	BCL9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9) (Legless homolog).

EP300_HUMAN
NC score	0.034973 (rank : 101)	θ value	0.0113563 (rank : 101)
Query Neighborhood Hits	223	Target Neighborhood Hits	821	Shared Neighborhood Hits	45
SwissProt Accessions	Q09472	Gene names	EP300, P300
Domain Architecture
Description	E1A-associated protein p300 (EC 2.3.1.48).

CBP_MOUSE
NC score	0.034541 (rank : 102)	θ value	0.279714 (rank : 107)
Query Neighborhood Hits	223	Target Neighborhood Hits	1051	Shared Neighborhood Hits	65
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

CBP_HUMAN
NC score	0.031700 (rank : 103)	θ value	0.0330416 (rank : 102)
Query Neighborhood Hits	223	Target Neighborhood Hits	941	Shared Neighborhood Hits	58
SwissProt Accessions	Q92793, O00147, Q16376	Gene names	CREBBP, CBP
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

MAGE1_HUMAN
NC score	0.026534 (rank : 104)	θ value	0.365318 (rank : 112)
Query Neighborhood Hits	223	Target Neighborhood Hits	1389	Shared Neighborhood Hits	90
SwissProt Accessions	Q9HCI5, Q86TG0, Q8TD92, Q9H216	Gene names	MAGEE1, HCA1, KIAA1587
Domain Architecture	No domain graphic available
Description	Melanoma-associated antigen E1 (MAGE-E1 antigen) (Hepatocellular carcinoma-associated protein 1).

SC24C_HUMAN
NC score	0.026469 (rank : 105)	θ value	5.27518 (rank : 197)
Query Neighborhood Hits	223	Target Neighborhood Hits	662	Shared Neighborhood Hits	69
SwissProt Accessions	P53992, Q8WV25	Gene names	SEC24C, KIAA0079
Domain Architecture
Description	Protein transport protein Sec24C (SEC24-related protein C).

MA2C1_HUMAN
NC score	0.026228 (rank : 106)	θ value	0.279714 (rank : 109)
Query Neighborhood Hits	223	Target Neighborhood Hits	21	Shared Neighborhood Hits	4
SwissProt Accessions	Q9NTJ4, Q13358, Q9UL64	Gene names	MAN2C1
Domain Architecture
Description	Alpha-mannosidase 2C1 (EC 3.2.1.24) (Alpha-D-mannoside mannohydrolase) (Mannosidase alpha class 2C member 1) (Alpha mannosidase 6A8B).

ADRM1_HUMAN
NC score	0.022433 (rank : 107)	θ value	0.62314 (rank : 118)
Query Neighborhood Hits	223	Target Neighborhood Hits	81	Shared Neighborhood Hits	10
SwissProt Accessions	Q16186, Q9H1P2	Gene names	ADRM1, GP110
Domain Architecture
Description	Adhesion-regulating molecule 1 precursor (110 kDa cell membrane glycoprotein) (Gp110).

MA2C1_MOUSE
NC score	0.022333 (rank : 108)	θ value	1.06291 (rank : 133)
Query Neighborhood Hits	223	Target Neighborhood Hits	14	Shared Neighborhood Hits	4
SwissProt Accessions	Q91W89	Gene names	Man2c1
Domain Architecture
Description	Alpha-mannosidase 2C1 (EC 3.2.1.24) (Alpha-D-mannoside mannohydrolase) (Mannosidase alpha class 2C member 1).

ADRM1_MOUSE
NC score	0.021587 (rank : 109)	θ value	1.38821 (rank : 141)
Query Neighborhood Hits	223	Target Neighborhood Hits	84	Shared Neighborhood Hits	11
SwissProt Accessions	Q9JKV1	Gene names	Adrm1, Gp110
Domain Architecture
Description	Adhesion-regulating molecule 1 precursor (110 kDa cell membrane glycoprotein) (Gp110) (ARM-1).

PER3_HUMAN
NC score	0.021204 (rank : 110)	θ value	0.62314 (rank : 120)
Query Neighborhood Hits	223	Target Neighborhood Hits	479	Shared Neighborhood Hits	50
SwissProt Accessions	P56645, Q5H8X4, Q969K6, Q96S77, Q96S78, Q9C0J3, Q9NSP9, Q9UGU8	Gene names	PER3
Domain Architecture
Description	Period circadian protein 3 (hPER3).

MUC1_MOUSE
NC score	0.020623 (rank : 111)	θ value	1.06291 (rank : 135)
Query Neighborhood Hits	223	Target Neighborhood Hits	388	Shared Neighborhood Hits	32
SwissProt Accessions	Q02496	Gene names	Muc1, Muc-1
Domain Architecture
Description	Mucin-1 precursor (Polymorphic epithelial mucin) (PEMT) (Episialin).

WFS1_HUMAN
NC score	0.017846 (rank : 112)	θ value	1.38821 (rank : 150)
Query Neighborhood Hits	223	Target Neighborhood Hits	42	Shared Neighborhood Hits	6
SwissProt Accessions	O76024, Q8N6I3, Q9UNW6	Gene names	WFS1
Domain Architecture	No domain graphic available
Description	Wolframin.

PO121_HUMAN
NC score	0.016112 (rank : 113)	θ value	1.06291 (rank : 137)
Query Neighborhood Hits	223	Target Neighborhood Hits	344	Shared Neighborhood Hits	21
SwissProt Accessions	Q9Y2N3, O75115, Q9Y4S7	Gene names	POM121, KIAA0618, NUP121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa) (P145).

SGIP1_MOUSE
NC score	0.015094 (rank : 114)	θ value	1.06291 (rank : 139)
Query Neighborhood Hits	223	Target Neighborhood Hits	180	Shared Neighborhood Hits	15
SwissProt Accessions	Q8VD37, Q3UFU3, Q3UGA0, Q8BXX4, Q8C034, Q9CXT2	Gene names	Sgip1
Domain Architecture	No domain graphic available
Description	SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin- 3-interacting protein).

S23IP_MOUSE
NC score	0.014950 (rank : 115)	θ value	2.36792 (rank : 162)
Query Neighborhood Hits	223	Target Neighborhood Hits	363	Shared Neighborhood Hits	39
SwissProt Accessions	Q6NZC7, Q8BXY6	Gene names	Sec23ip
Domain Architecture	No domain graphic available
Description	SEC23-interacting protein.

PODXL_HUMAN
NC score	0.014845 (rank : 116)	θ value	1.81305 (rank : 152)
Query Neighborhood Hits	223	Target Neighborhood Hits	191	Shared Neighborhood Hits	19
SwissProt Accessions	O00592	Gene names	PODXL, PCLP, PCLP1
Domain Architecture
Description	Podocalyxin-like protein 1 precursor.

DAG1_MOUSE
NC score	0.014748 (rank : 117)	θ value	1.38821 (rank : 144)
Query Neighborhood Hits	223	Target Neighborhood Hits	100	Shared Neighborhood Hits	9
SwissProt Accessions	Q62165, Q61094, Q61141, Q61497	Gene names	Dag1, Dag-1
Domain Architecture
Description	Dystroglycan precursor (Dystrophin-associated glycoprotein 1) [Contains: Alpha-dystroglycan (Alpha-DG); Beta-dystroglycan (Beta- DG)].

UBQL2_MOUSE
NC score	0.014483 (rank : 118)	θ value	0.0961366 (rank : 105)
Query Neighborhood Hits	223	Target Neighborhood Hits	114	Shared Neighborhood Hits	7
SwissProt Accessions	Q9QZM0, Q7TSJ8, Q8VDH9	Gene names	Ubqln2, Plic2
Domain Architecture
Description	Ubiquilin-2 (Protein linking IAP with cytoskeleton 2) (PLIC-2) (Ubiquitin-like product Chap1/Dsk2) (DSK2 homolog) (Chap1).

BRD7_HUMAN
NC score	0.014208 (rank : 119)	θ value	4.03905 (rank : 174)
Query Neighborhood Hits	223	Target Neighborhood Hits	94	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NPI1, Q4VC09, Q8N2L9, Q96KA4, Q9BV48, Q9UH59	Gene names	BRD7, BP75, CELTIX1
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 7 (75 kDa bromodomain protein) (Protein CELTIX-1).

PO121_MOUSE
NC score	0.014132 (rank : 120)	θ value	1.06291 (rank : 138)
Query Neighborhood Hits	223	Target Neighborhood Hits	345	Shared Neighborhood Hits	23
SwissProt Accessions	Q8K3Z9, Q7TSH5	Gene names	Pom121, Nup121
Domain Architecture	No domain graphic available
Description	Nuclear envelope pore membrane protein POM 121 (Pore membrane protein of 121 kDa).

DAG1_HUMAN
NC score	0.014042 (rank : 121)	θ value	3.0926 (rank : 167)
Query Neighborhood Hits	223	Target Neighborhood Hits	104	Shared Neighborhood Hits	10
SwissProt Accessions	Q14118	Gene names	DAG1
Domain Architecture
Description	Dystroglycan precursor (Dystrophin-associated glycoprotein 1) [Contains: Alpha-dystroglycan (Alpha-DG); Beta-dystroglycan (Beta- DG)].

BRD7_MOUSE
NC score	0.013847 (rank : 122)	θ value	4.03905 (rank : 175)
Query Neighborhood Hits	223	Target Neighborhood Hits	141	Shared Neighborhood Hits	8
SwissProt Accessions	O88665, Q3UQ56, Q3UU06, Q9CT78	Gene names	Brd7, Bp75
Domain Architecture	No domain graphic available
Description	Bromodomain-containing protein 7 (75 kDa bromodomain protein).

ARI1A_HUMAN
NC score	0.013154 (rank : 123)	θ value	3.0926 (rank : 165)
Query Neighborhood Hits	223	Target Neighborhood Hits	787	Shared Neighborhood Hits	46
SwissProt Accessions	O14497, Q53FK9, Q5T0W1, Q5T0W2, Q5T0W3, Q8NFD6, Q96T89, Q9BY33, Q9HBJ5, Q9UPZ1	Gene names	ARID1A, C1orf4, OSA1, SMARCF1
Domain Architecture
Description	AT-rich interactive domain-containing protein 1A (ARID domain- containing protein 1A) (SWI/SNF-related, matrix-associated, actin- dependent regulator of chromatin subfamily F member 1) (SWI-SNF complex protein p270) (B120) (SWI-like protein) (Osa homolog 1) (hOSA1) (hELD) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A).

UBQL2_HUMAN
NC score	0.012830 (rank : 124)	θ value	0.47712 (rank : 116)
Query Neighborhood Hits	223	Target Neighborhood Hits	103	Shared Neighborhood Hits	7
SwissProt Accessions	Q9UHD9, O94798, Q9H3W6, Q9HAZ4	Gene names	UBQLN2, PLIC2
Domain Architecture
Description	Ubiquilin-2 (Protein linking IAP with cytoskeleton 2) (PLIC-2) (hPLIC- 2) (Ubiquitin-like product Chap1/Dsk2) (DSK2 homolog) (Chap1).

SF3A2_MOUSE
NC score	0.012649 (rank : 125)	θ value	2.36792 (rank : 163)
Query Neighborhood Hits	223	Target Neighborhood Hits	247	Shared Neighborhood Hits	17
SwissProt Accessions	Q62203	Gene names	Sf3a2, Sap62
Domain Architecture
Description	Splicing factor 3A subunit 2 (Spliceosome-associated protein 62) (SAP 62) (SF3a66).

4ET_MOUSE
NC score	0.012580 (rank : 126)	θ value	1.06291 (rank : 127)
Query Neighborhood Hits	223	Target Neighborhood Hits	103	Shared Neighborhood Hits	8
SwissProt Accessions	Q9EST3, Q9CSS3	Gene names	Eif4enif1, Clast4
Domain Architecture	No domain graphic available
Description	Eukaryotic translation initiation factor 4E transporter (eIF4E transporter) (4E-T) (Eukaryotic translation initiation factor 4E nuclear import factor 1).

SF01_HUMAN
NC score	0.012327 (rank : 127)	θ value	4.03905 (rank : 185)
Query Neighborhood Hits	223	Target Neighborhood Hits	287	Shared Neighborhood Hits	21
SwissProt Accessions	Q15637, Q14818, Q14819, Q15913, Q8IY00, Q92744, Q92745, Q969H7, Q9BW01, Q9UEI0	Gene names	SF1, ZFM1, ZNF162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (Zinc finger gene in MEN1 locus) (Mammalian branch point-binding protein mBBP) (BBP).

CS007_MOUSE
NC score	0.011405 (rank : 128)	θ value	1.06291 (rank : 129)
Query Neighborhood Hits	223	Target Neighborhood Hits	464	Shared Neighborhood Hits	29
SwissProt Accessions	Q6ZPZ3	Gene names	Kiaa1064
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein C19orf7 homolog.

SF01_MOUSE
NC score	0.011160 (rank : 129)	θ value	4.03905 (rank : 186)
Query Neighborhood Hits	223	Target Neighborhood Hits	240	Shared Neighborhood Hits	17
SwissProt Accessions	Q64213, O08817, P70167, Q61454, Q921Z4	Gene names	Sf1, Zfm1, Zfp162
Domain Architecture
Description	Splicing factor 1 (Zinc finger protein 162) (Transcription factor ZFM1) (mZFM) (Zinc finger gene in MEN1 locus) (Mammalian branch point- binding protein mBBP) (BBP) (CW17).

GMEB2_HUMAN
NC score	0.011108 (rank : 130)	θ value	1.38821 (rank : 145)
Query Neighborhood Hits	223	Target Neighborhood Hits	62	Shared Neighborhood Hits	6
SwissProt Accessions	Q9UKD1, Q5TDS0, Q9H431, Q9H4X7, Q9H4X8, Q9UF78, Q9ULF1	Gene names	GMEB2, KIAA1269
Domain Architecture
Description	Glucocorticoid modulatory element-binding protein 2 (GMEB-2) (Parvovirus initiation factor p79) (PIF p79) (DNA-binding protein p79PIF).

GGN_MOUSE
NC score	0.011057 (rank : 131)	θ value	1.81305 (rank : 151)
Query Neighborhood Hits	223	Target Neighborhood Hits	311	Shared Neighborhood Hits	18
SwissProt Accessions	Q80WJ1, Q5EBP4, Q80WI9, Q80WJ0	Gene names	Ggn
Domain Architecture	No domain graphic available
Description	Gametogenetin.

CCNK_MOUSE
NC score	0.010942 (rank : 132)	θ value	0.62314 (rank : 119)
Query Neighborhood Hits	223	Target Neighborhood Hits	350	Shared Neighborhood Hits	16
SwissProt Accessions	O88874, Q8R068	Gene names	Ccnk
Domain Architecture	No domain graphic available
Description	Cyclin-K.

CO4A5_HUMAN
NC score	0.010564 (rank : 133)	θ value	8.99809 (rank : 212)
Query Neighborhood Hits	223	Target Neighborhood Hits	383	Shared Neighborhood Hits	29
SwissProt Accessions	P29400, Q16006, Q16126, Q6LD84	Gene names	COL4A5
Domain Architecture
Description	Collagen alpha-5(IV) chain precursor.

DEN1A_MOUSE
NC score	0.010435 (rank : 134)	θ value	0.365318 (rank : 111)
Query Neighborhood Hits	223	Target Neighborhood Hits	178	Shared Neighborhood Hits	16
SwissProt Accessions	Q8K382	Gene names	Dennd1a
Domain Architecture	No domain graphic available
Description	DENN domain-containing protein 1A.

MUC2_HUMAN
NC score	0.010183 (rank : 135)	θ value	0.813845 (rank : 124)
Query Neighborhood Hits	223	Target Neighborhood Hits	906	Shared Neighborhood Hits	34
SwissProt Accessions	Q02817, Q14878	Gene names	MUC2, SMUC
Domain Architecture
Description	Mucin-2 precursor (Intestinal mucin-2).

TENS4_MOUSE
NC score	0.010124 (rank : 136)	θ value	1.38821 (rank : 149)
Query Neighborhood Hits	223	Target Neighborhood Hits	225	Shared Neighborhood Hits	19
SwissProt Accessions	Q8BZ33, Q3TCM8, Q7TNR5	Gene names	Tns4
Domain Architecture	No domain graphic available
Description	Tensin-4 precursor.

ZC3H5_MOUSE
NC score	0.010094 (rank : 137)	θ value	0.813845 (rank : 126)
Query Neighborhood Hits	223	Target Neighborhood Hits	136	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BL48, Q8BVI6, Q99JZ8, Q99LL9	Gene names	Zc3h5, Kiaa1753, Zc3hdc5
Domain Architecture	No domain graphic available
Description	Zinc finger CCCH domain-containing protein 5.

EP400_HUMAN
NC score	0.009975 (rank : 138)	θ value	1.06291 (rank : 132)
Query Neighborhood Hits	223	Target Neighborhood Hits	556	Shared Neighborhood Hits	31
SwissProt Accessions	Q96L91, O15411, Q6P2F5, Q8N8Q7, Q8NE05, Q96JK7, Q9P230	Gene names	EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Domain Architecture	No domain graphic available
Description	E1A-binding protein p400 (EC 3.6.1.-) (p400 kDa SWI2/SNF2-related protein) (Domino homolog) (hDomino) (CAG repeat protein 32) (Trinucleotide repeat-containing gene 12 protein).

RPB1_MOUSE
NC score	0.009808 (rank : 139)	θ value	1.81305 (rank : 155)
Query Neighborhood Hits	223	Target Neighborhood Hits	363	Shared Neighborhood Hits	18
SwissProt Accessions	P08775	Gene names	Polr2a, Rpii215, Rpo2-1
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

RPB1_HUMAN
NC score	0.009747 (rank : 140)	θ value	1.81305 (rank : 154)
Query Neighborhood Hits	223	Target Neighborhood Hits	362	Shared Neighborhood Hits	18
SwissProt Accessions	P24928	Gene names	POLR2A
Domain Architecture
Description	DNA-directed RNA polymerase II largest subunit (EC 2.7.7.6) (RPB1).

CT112_HUMAN
NC score	0.009683 (rank : 141)	θ value	2.36792 (rank : 157)
Query Neighborhood Hits	223	Target Neighborhood Hits	30	Shared Neighborhood Hits	4
SwissProt Accessions	Q96MY1, Q5JYB7, Q6P0Y4, Q9BR34, Q9NQF6	Gene names	C20orf112
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf112.

MINT_MOUSE
NC score	0.009576 (rank : 142)	θ value	1.06291 (rank : 134)
Query Neighborhood Hits	223	Target Neighborhood Hits	1514	Shared Neighborhood Hits	61
SwissProt Accessions	Q62504, Q80TN9, Q99PS4, Q9QZW2	Gene names	Spen, Kiaa0929, Mint, Sharp
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

GMEB2_MOUSE
NC score	0.009486 (rank : 143)	θ value	4.03905 (rank : 178)
Query Neighborhood Hits	223	Target Neighborhood Hits	64	Shared Neighborhood Hits	5
SwissProt Accessions	P58929, Q6PCY0	Gene names	Gmeb2
Domain Architecture	No domain graphic available
Description	Glucocorticoid modulatory element-binding protein 2 (GMEB-2).

RBM12_HUMAN
NC score	0.009412 (rank : 144)	θ value	4.03905 (rank : 182)
Query Neighborhood Hits	223	Target Neighborhood Hits	298	Shared Neighborhood Hits	17
SwissProt Accessions	Q9NTZ6, O94865, Q8N3B1, Q9H196	Gene names	RBM12, KIAA0765
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

UBP2L_HUMAN
NC score	0.009268 (rank : 145)	θ value	4.03905 (rank : 189)
Query Neighborhood Hits	223	Target Neighborhood Hits	170	Shared Neighborhood Hits	11
SwissProt Accessions	Q14157, Q5VU75, Q5VU76, Q9BTU3, Q9UGL5	Gene names	UBAP2L, KIAA0144, NICE4
Domain Architecture
Description	Ubiquitin-associated protein 2-like (Protein NICE-4).

UBP2L_MOUSE
NC score	0.009202 (rank : 146)	θ value	4.03905 (rank : 190)
Query Neighborhood Hits	223	Target Neighborhood Hits	173	Shared Neighborhood Hits	11
SwissProt Accessions	Q80X50, Q8BIT6, Q8BIW4, Q8BJ01, Q8CIG7, Q8K102, Q9CRT6	Gene names	Ubap2l
Domain Architecture	No domain graphic available
Description	Ubiquitin-associated protein 2-like.

RSMB_HUMAN
NC score	0.009143 (rank : 147)	θ value	8.99809 (rank : 218)
Query Neighborhood Hits	223	Target Neighborhood Hits	117	Shared Neighborhood Hits	14
SwissProt Accessions	P14678, Q15490, Q9UIS5	Gene names	SNRPB, COD, SNRPB1
Domain Architecture
Description	Small nuclear ribonucleoprotein-associated proteins B and B' (snRNP-B) (Sm protein B/B') (Sm-B/Sm-B') (SmB/SmB').

RSMN_HUMAN
NC score	0.009109 (rank : 148)	θ value	8.99809 (rank : 220)
Query Neighborhood Hits	223	Target Neighborhood Hits	110	Shared Neighborhood Hits	15
SwissProt Accessions	P63162, P14648, P17135	Gene names	SNRPN, HCERN3, SMN
Domain Architecture	No domain graphic available
Description	Small nuclear ribonucleoprotein-associated protein N (snRNP-N) (Sm protein N) (Sm-N) (SmN) (Sm-D) (Tissue-specific-splicing protein).

RSMN_MOUSE
NC score	0.009109 (rank : 149)	θ value	8.99809 (rank : 221)
Query Neighborhood Hits	223	Target Neighborhood Hits	110	Shared Neighborhood Hits	15
SwissProt Accessions	P63163, P14648, P17135	Gene names	Snrpn, Smn
Domain Architecture	No domain graphic available
Description	Small nuclear ribonucleoprotein-associated protein N (snRNP-N) (Sm protein N) (Sm-N) (SmN) (Sm-D) (Tissue-specific-splicing protein).

RBM12_MOUSE
NC score	0.009015 (rank : 150)	θ value	4.03905 (rank : 183)
Query Neighborhood Hits	223	Target Neighborhood Hits	313	Shared Neighborhood Hits	16
SwissProt Accessions	Q8R4X3, Q8K373, Q8R302, Q9CS80	Gene names	Rbm12
Domain Architecture
Description	RNA-binding protein 12 (RNA-binding motif protein 12) (SH3/WW domain anchor protein in the nucleus) (SWAN).

TAB2_HUMAN
NC score	0.008988 (rank : 151)	θ value	1.38821 (rank : 148)
Query Neighborhood Hits	223	Target Neighborhood Hits	169	Shared Neighborhood Hits	5
SwissProt Accessions	Q9NYJ8, O94838, Q6I9W8, Q76N06, Q9UFP7	Gene names	MAP3K7IP2, KIAA0733, TAB2
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 2 (TAK1-binding protein 2).

MUC5B_HUMAN
NC score	0.008838 (rank : 152)	θ value	0.47712 (rank : 115)
Query Neighborhood Hits	223	Target Neighborhood Hits	1020	Shared Neighborhood Hits	42
SwissProt Accessions	Q9HC84, O00447, O00573, O14985, O15494, O95291, O95451, Q14881, Q99552, Q9UE28	Gene names	MUC5B, MUC5
Domain Architecture
Description	Mucin-5B precursor (Mucin-5 subtype B, tracheobronchial) (High molecular weight salivary mucin MG1) (Sublingual gland mucin).

RSMB_MOUSE
NC score	0.008667 (rank : 153)	θ value	8.99809 (rank : 219)
Query Neighborhood Hits	223	Target Neighborhood Hits	93	Shared Neighborhood Hits	11
SwissProt Accessions	P27048, Q3UJT1	Gene names	Snrpb
Domain Architecture
Description	Small nuclear ribonucleoprotein-associated protein B (snRNP-B) (Sm protein B) (Sm-B) (SmB).

NASP_HUMAN
NC score	0.008633 (rank : 154)	θ value	1.06291 (rank : 136)
Query Neighborhood Hits	223	Target Neighborhood Hits	709	Shared Neighborhood Hits	14
SwissProt Accessions	P49321, Q96A69, Q9BTW2	Gene names	NASP
Domain Architecture
Description	Nuclear autoantigenic sperm protein (NASP).

ATF6B_MOUSE
NC score	0.008597 (rank : 155)	θ value	1.38821 (rank : 143)
Query Neighborhood Hits	223	Target Neighborhood Hits	97	Shared Neighborhood Hits	6
SwissProt Accessions	O35451	Gene names	Crebl1
Domain Architecture
Description	Cyclic AMP-dependent transcription factor ATF-6 beta (Activating transcription factor 6 beta) (ATF6-beta) (cAMP-responsive element- binding protein-like 1) (cAMP response element-binding protein-related protein) (Creb-rp).

ENAH_MOUSE
NC score	0.008447 (rank : 156)	θ value	1.06291 (rank : 131)
Query Neighborhood Hits	223	Target Neighborhood Hits	919	Shared Neighborhood Hits	26
SwissProt Accessions	Q03173, P70430, P70431, P70432, P70433, Q5D053	Gene names	Enah, Mena, Ndpp1
Domain Architecture
Description	Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1).

SON_MOUSE
NC score	0.008437 (rank : 157)	θ value	8.99809 (rank : 222)
Query Neighborhood Hits	223	Target Neighborhood Hits	957	Shared Neighborhood Hits	60
SwissProt Accessions	Q9QX47, Q9CQ12, Q9CQK6, Q9QXP5	Gene names	Son
Domain Architecture
Description	SON protein.

MUC13_MOUSE
NC score	0.008419 (rank : 158)	θ value	0.813845 (rank : 123)
Query Neighborhood Hits	223	Target Neighborhood Hits	447	Shared Neighborhood Hits	16
SwissProt Accessions	P19467	Gene names	Muc13, Ly64
Domain Architecture
Description	Mucin-13 precursor (Cell surface antigen 114/A10) (Lymphocyte antigen 64).

GGN_HUMAN
NC score	0.008394 (rank : 159)	θ value	6.88961 (rank : 206)
Query Neighborhood Hits	223	Target Neighborhood Hits	269	Shared Neighborhood Hits	13
SwissProt Accessions	Q86UU5, Q7RTU6, Q86UU4, Q8NAA1	Gene names	GGN
Domain Architecture	No domain graphic available
Description	Gametogenetin.

TAB3_HUMAN
NC score	0.008382 (rank : 160)	θ value	5.27518 (rank : 200)
Query Neighborhood Hits	223	Target Neighborhood Hits	168	Shared Neighborhood Hits	11
SwissProt Accessions	Q8N5C8, Q6VQR0	Gene names	MAP3K7IP3, TAB3
Domain Architecture	No domain graphic available
Description	Mitogen-activated protein kinase kinase kinase 7-interacting protein 3 (TAK1-binding protein 3) (NF-kappa-B-activating protein 1).

PAPOA_MOUSE
NC score	0.008343 (rank : 161)	θ value	0.365318 (rank : 113)
Query Neighborhood Hits	223	Target Neighborhood Hits	115	Shared Neighborhood Hits	6
SwissProt Accessions	Q61183, Q61208, Q61209, Q8K4X2	Gene names	Papola, Pap, Plap
Domain Architecture
Description	Poly(A) polymerase alpha (EC 2.7.7.19) (PAP) (Polynucleotide adenylyltransferase).

CT112_MOUSE
NC score	0.008179 (rank : 162)	θ value	5.27518 (rank : 195)
Query Neighborhood Hits	223	Target Neighborhood Hits	35	Shared Neighborhood Hits	4
SwissProt Accessions	Q6DIB4	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C20orf112 homolog.

ZCHC8_HUMAN
NC score	0.007818 (rank : 163)	θ value	6.88961 (rank : 208)
Query Neighborhood Hits	223	Target Neighborhood Hits	92	Shared Neighborhood Hits	4
SwissProt Accessions	Q6NZY4, Q7L2P6, Q8N2K5, Q96SK7, Q9NSS2, Q9NSS3	Gene names	ZCCHC8
Domain Architecture	No domain graphic available
Description	Zinc finger CCHC domain-containing protein 8.

SMR3A_HUMAN
NC score	0.007545 (rank : 164)	θ value	5.27518 (rank : 198)
Query Neighborhood Hits	223	Target Neighborhood Hits	93	Shared Neighborhood Hits	5
SwissProt Accessions	Q99954	Gene names	SMR3A, PBI, PROL5
Domain Architecture	No domain graphic available
Description	Submaxillary gland androgen-regulated protein 3 homolog A precursor (Proline-rich protein 5) (Proline-rich protein PBI).

YLPM1_MOUSE
NC score	0.007538 (rank : 165)	θ value	4.03905 (rank : 192)
Query Neighborhood Hits	223	Target Neighborhood Hits	505	Shared Neighborhood Hits	25
SwissProt Accessions	Q9R0I7, Q7TMM4	Gene names	Ylpm1, Zap, Zap3
Domain Architecture	No domain graphic available
Description	YLP motif-containing protein 1 (Nuclear protein ZAP3).

UBE4B_HUMAN
NC score	0.007476 (rank : 166)	θ value	2.36792 (rank : 164)
Query Neighborhood Hits	223	Target Neighborhood Hits	158	Shared Neighborhood Hits	13
SwissProt Accessions	O95155, O75169, O95338, Q5SZ12, Q5SZ16, Q96QD4, Q9BYI7	Gene names	UBE4B, HDNB1, KIAA0684, UFD2
Domain Architecture
Description	Ubiquitin conjugation factor E4 B (Ubiquitin fusion degradation protein 2) (Homozygously deleted in neuroblastoma 1).

TLE1_MOUSE
NC score	0.007182 (rank : 167)	θ value	1.06291 (rank : 140)
Query Neighborhood Hits	223	Target Neighborhood Hits	491	Shared Neighborhood Hits	32
SwissProt Accessions	Q62440	Gene names	Tle1, Grg1
Domain Architecture
Description	Transducin-like enhancer protein 1 (Groucho-related protein 1) (Grg- 1).

NCOA2_HUMAN
NC score	0.007129 (rank : 168)	θ value	4.03905 (rank : 180)
Query Neighborhood Hits	223	Target Neighborhood Hits	281	Shared Neighborhood Hits	26
SwissProt Accessions	Q15596	Gene names	NCOA2, TIF2
Domain Architecture
Description	Nuclear receptor coactivator 2 (NCoA-2) (Transcriptional intermediary factor 2).

SSXT_HUMAN
NC score	0.007095 (rank : 169)	θ value	6.88961 (rank : 207)
Query Neighborhood Hits	223	Target Neighborhood Hits	125	Shared Neighborhood Hits	12
SwissProt Accessions	Q15532, Q16404, Q9BXC6	Gene names	SS18, SSXT, SYT
Domain Architecture
Description	SSXT protein (Synovial sarcoma, translocated to X chromosome) (SYT protein).

CF142_MOUSE
NC score	0.006919 (rank : 170)	θ value	5.27518 (rank : 193)
Query Neighborhood Hits	223	Target Neighborhood Hits	22	Shared Neighborhood Hits	2
SwissProt Accessions	Q5FW52, Q9D6X9	Gene names
Domain Architecture	No domain graphic available
Description	Protein C6orf142 homolog.

CB017_HUMAN
NC score	0.006859 (rank : 171)	θ value	4.03905 (rank : 176)
Query Neighborhood Hits	223	Target Neighborhood Hits	38	Shared Neighborhood Hits	3
SwissProt Accessions	Q8NC44, Q6P1P5, Q9H0K7	Gene names	C2orf17
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C2orf17.

SFPQ_MOUSE
NC score	0.006802 (rank : 172)	θ value	0.813845 (rank : 125)
Query Neighborhood Hits	223	Target Neighborhood Hits	958	Shared Neighborhood Hits	29
SwissProt Accessions	Q8VIJ6, Q9ERW2	Gene names	Sfpq
Domain Architecture	No domain graphic available
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit).

RGDSR_HUMAN
NC score	0.006687 (rank : 173)	θ value	1.81305 (rank : 153)
Query Neighborhood Hits	223	Target Neighborhood Hits	63	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IZJ4	Gene names	RGR
Domain Architecture
Description	Ral-GDS-related protein (hRGR).

SMCA2_HUMAN
NC score	0.006349 (rank : 174)	θ value	0.279714 (rank : 110)
Query Neighborhood Hits	223	Target Neighborhood Hits	503	Shared Neighborhood Hits	28
SwissProt Accessions	P51531	Gene names	SMARCA2, BRM, SNF2A, SNF2L2
Domain Architecture
Description	Probable global transcription activator SNF2L2 (EC 3.6.1.-) (ATP- dependent helicase SMARCA2) (SNF2-alpha) (SWI/SNF-related matrix- associated actin-dependent regulator of chromatin subfamily A member 2) (hBRM).

SFPQ_HUMAN
NC score	0.006228 (rank : 175)	θ value	3.0926 (rank : 173)
Query Neighborhood Hits	223	Target Neighborhood Hits	986	Shared Neighborhood Hits	31
SwissProt Accessions	P23246, P30808	Gene names	SFPQ, PSF
Domain Architecture
Description	Splicing factor, proline- and glutamine-rich (Polypyrimidine tract- binding protein-associated-splicing factor) (PTB-associated-splicing factor) (PSF) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA-pairing protein) (hPOMp100).

SRBP1_HUMAN
NC score	0.006200 (rank : 176)	θ value	4.03905 (rank : 187)
Query Neighborhood Hits	223	Target Neighborhood Hits	225	Shared Neighborhood Hits	14
SwissProt Accessions	P36956, Q16062	Gene names	SREBF1, SREBP1
Domain Architecture
Description	Sterol regulatory element-binding protein 1 (SREBP-1) (Sterol regulatory element-binding transcription factor 1).

DIAP3_HUMAN
NC score	0.006176 (rank : 177)	θ value	0.47712 (rank : 114)
Query Neighborhood Hits	223	Target Neighborhood Hits	209	Shared Neighborhood Hits	8
SwissProt Accessions	Q9NSV4, Q5T2S7, Q5XKF6, Q6MZF0, Q6NUP0, Q86VS4, Q8NAV4	Gene names	DIAPH3, DIAP3
Domain Architecture	No domain graphic available
Description	Protein diaphanous homolog 3 (Diaphanous-related formin-3) (DRF3).

HCN4_MOUSE
NC score	0.005891 (rank : 178)	θ value	0.279714 (rank : 108)
Query Neighborhood Hits	223	Target Neighborhood Hits	284	Shared Neighborhood Hits	17
SwissProt Accessions	O70507	Gene names	Hcn4, Bcng3
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Brain cyclic nucleotide-gated channel 3) (BCNG-3).

RIN3_MOUSE
NC score	0.005440 (rank : 179)	θ value	4.03905 (rank : 184)
Query Neighborhood Hits	223	Target Neighborhood Hits	239	Shared Neighborhood Hits	16
SwissProt Accessions	P59729	Gene names	Rin3
Domain Architecture
Description	Ras and Rab interactor 3 (Ras interaction/interference protein 3).

MUCDL_MOUSE
NC score	0.005396 (rank : 180)	θ value	2.36792 (rank : 159)
Query Neighborhood Hits	223	Target Neighborhood Hits	461	Shared Neighborhood Hits	28
SwissProt Accessions	Q8VHF2, Q8CEJ3, Q9D8I9	Gene names	Mucdhl
Domain Architecture
Description	Mucin and cadherin-like protein precursor (Mu-protocadherin).

TLE1_HUMAN
NC score	0.005243 (rank : 181)	θ value	5.27518 (rank : 202)
Query Neighborhood Hits	223	Target Neighborhood Hits	485	Shared Neighborhood Hits	30
SwissProt Accessions	Q04724, Q5T3G4, Q969V9	Gene names	TLE1
Domain Architecture
Description	Transducin-like enhancer protein 1 (ESG1) (E(Sp1) homolog).

MINT_HUMAN
NC score	0.005192 (rank : 182)	θ value	1.38821 (rank : 147)
Query Neighborhood Hits	223	Target Neighborhood Hits	1291	Shared Neighborhood Hits	39
SwissProt Accessions	Q96T58, Q9H9A8, Q9NWH5, Q9UQ01, Q9Y556	Gene names	SPEN, KIAA0929, MINT, SHARP
Domain Architecture
Description	Msx2-interacting protein (SPEN homolog) (SMART/HDAC1-associated repressor protein).

MLL2_HUMAN
NC score	0.004686 (rank : 183)	θ value	3.0926 (rank : 169)
Query Neighborhood Hits	223	Target Neighborhood Hits	1788	Shared Neighborhood Hits	58
SwissProt Accessions	O14686, O14687	Gene names	MLL2, ALR
Domain Architecture
Description	Myeloid/lymphoid or mixed-lineage leukemia protein 2 (ALL1-related protein).

FMNL_HUMAN
NC score	0.004580 (rank : 184)	θ value	8.99809 (rank : 214)
Query Neighborhood Hits	223	Target Neighborhood Hits	529	Shared Neighborhood Hits	21
SwissProt Accessions	O95466, Q6DKG5, Q6IBP3, Q86UH1, Q8N671, Q8TDH1, Q96H10	Gene names	FMNL1, C17orf1, C17orf1B, FMNL
Domain Architecture
Description	Formin-like protein 1 (Leukocyte formin) (CLL-associated antigen KW- 13).

PCQAP_HUMAN
NC score	0.004457 (rank : 185)	θ value	3.0926 (rank : 171)
Query Neighborhood Hits	223	Target Neighborhood Hits	549	Shared Neighborhood Hits	19
SwissProt Accessions	Q96RN5, O15413, Q6IC31, Q8NF16, Q96CT0, Q96IH7, Q9P1T3	Gene names	PCQAP, ARC105, CTG7A, TIG1
Domain Architecture	No domain graphic available
Description	Positive cofactor 2 glutamine/Q-rich-associated protein (PC2 glutamine/Q-rich-associated protein) (TPA-inducible gene 1 protein) (TIG-1) (Activator-recruited cofactor 105 kDa component) (ARC105) (CTG repeat protein 7a).

CNOT3_MOUSE
NC score	0.004248 (rank : 186)	θ value	4.03905 (rank : 177)
Query Neighborhood Hits	223	Target Neighborhood Hits	504	Shared Neighborhood Hits	15
SwissProt Accessions	Q8K0V4	Gene names	Cnot3, Not3
Domain Architecture
Description	CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3).

ROD1_HUMAN
NC score	0.003870 (rank : 187)	θ value	2.36792 (rank : 161)
Query Neighborhood Hits	223	Target Neighborhood Hits	60	Shared Neighborhood Hits	5
SwissProt Accessions	O95758, Q86YB3, Q86YH9	Gene names	ROD1
Domain Architecture	No domain graphic available
Description	Regulator of differentiation 1 (Rod1).

COHA1_HUMAN
NC score	0.003661 (rank : 188)	θ value	8.99809 (rank : 213)
Query Neighborhood Hits	223	Target Neighborhood Hits	400	Shared Neighborhood Hits	26
SwissProt Accessions	Q9UMD9, Q02802, Q99018, Q9NQK9, Q9UC14	Gene names	COL17A1, BP180, BPAG2
Domain Architecture	No domain graphic available
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

ATX1_HUMAN
NC score	0.003573 (rank : 189)	θ value	8.99809 (rank : 211)
Query Neighborhood Hits	223	Target Neighborhood Hits	79	Shared Neighborhood Hits	6
SwissProt Accessions	P54253, Q9UJG2, Q9Y4J1	Gene names	ATXN1, ATX1, SCA1
Domain Architecture
Description	Ataxin-1 (Spinocerebellar ataxia type 1 protein).

CDSN_MOUSE
NC score	0.003461 (rank : 190)	θ value	6.88961 (rank : 205)
Query Neighborhood Hits	223	Target Neighborhood Hits	131	Shared Neighborhood Hits	3
SwissProt Accessions	Q7TPC1	Gene names	Cdsn
Domain Architecture	No domain graphic available
Description	Corneodesmosin precursor.

OLIG3_MOUSE
NC score	0.003259 (rank : 191)	θ value	3.0926 (rank : 170)
Query Neighborhood Hits	223	Target Neighborhood Hits	76	Shared Neighborhood Hits	3
SwissProt Accessions	Q6PFG8, Q9EQW5	Gene names	Olig3, Bhlhb7
Domain Architecture	No domain graphic available
Description	Oligodendrocyte transcription factor 3 (Oligo3) (Oligodendrocyte- specific bHLH transcription factor 3) (Basic helix-loop-helix domain- containing class B protein 7).

COHA1_MOUSE
NC score	0.003223 (rank : 192)	θ value	5.27518 (rank : 194)
Query Neighborhood Hits	223	Target Neighborhood Hits	414	Shared Neighborhood Hits	25
SwissProt Accessions	Q07563, Q99LK8	Gene names	Col17a1, Bp180, Bpag2
Domain Architecture
Description	Collagen alpha-1(XVII) chain (Bullous pemphigoid antigen 2) (180 kDa bullous pemphigoid antigen 2).

ARHG1_HUMAN
NC score	0.002979 (rank : 193)	θ value	1.38821 (rank : 142)
Query Neighborhood Hits	223	Target Neighborhood Hits	176	Shared Neighborhood Hits	6
SwissProt Accessions	Q92888, O00513, Q8N4J4, Q96BF4, Q96F17, Q9BSB1	Gene names	ARHGEF1
Domain Architecture
Description	Rho guanine nucleotide exchange factor 1 (p115-RhoGEF) (p115RhoGEF) (115 kDa guanine nucleotide exchange factor) (Sub1.5).

GPR64_HUMAN
NC score	0.002935 (rank : 194)	θ value	4.03905 (rank : 179)
Query Neighborhood Hits	223	Target Neighborhood Hits	207	Shared Neighborhood Hits	12
SwissProt Accessions	Q8IZP9, O00406, Q8IWT2, Q8IZE4, Q8IZE5, Q8IZE6, Q8IZE7, Q8IZP3, Q8IZP4	Gene names	GPR64, HE6, TM7LN2
Domain Architecture
Description	G-protein coupled receptor 64 precursor (Epididymis-specific protein 6) (He6 receptor).

GRSF1_MOUSE
NC score	0.002806 (rank : 195)	θ value	8.99809 (rank : 215)
Query Neighborhood Hits	223	Target Neighborhood Hits	60	Shared Neighborhood Hits	4
SwissProt Accessions	Q8C5Q4, Q8BR05, Q8BRG7	Gene names	Grsf1
Domain Architecture	No domain graphic available
Description	G-rich sequence factor 1 (GRSF-1).

RHG26_HUMAN
NC score	0.002499 (rank : 196)	θ value	0.62314 (rank : 121)
Query Neighborhood Hits	223	Target Neighborhood Hits	281	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UNA1, O75117, Q9BYS6, Q9BYS7, Q9UJ00	Gene names	ARHGAP26, GRAF, KIAA0621, OPHN1L
Domain Architecture
Description	Rho-GTPase-activating protein 26 (Oligophrenin-1-like protein) (GTPase regulator associated with focal adhesion kinase).

TCF7_HUMAN
NC score	0.002397 (rank : 197)	θ value	4.03905 (rank : 188)
Query Neighborhood Hits	223	Target Neighborhood Hits	186	Shared Neighborhood Hits	12
SwissProt Accessions	P36402, Q9UKI4	Gene names	TCF7, TCF1
Domain Architecture
Description	Transcription factor 7 (T-cell-specific transcription factor 1) (TCF- 1) (T-cell factor 1).

AUXI_MOUSE
NC score	0.002351 (rank : 198)	θ value	6.88961 (rank : 203)
Query Neighborhood Hits	223	Target Neighborhood Hits	114	Shared Neighborhood Hits	6
SwissProt Accessions	Q80TZ3, Q6P2K9, Q8C7L9	Gene names	Dnajc6, Kiaa0473
Domain Architecture	No domain graphic available
Description	Putative tyrosine-protein phosphatase auxilin (EC 3.1.3.48) (DnaJ homolog subfamily C member 6).

CHFR_HUMAN
NC score	0.001738 (rank : 199)	θ value	3.0926 (rank : 166)
Query Neighborhood Hits	223	Target Neighborhood Hits	255	Shared Neighborhood Hits	2
SwissProt Accessions	Q96EP1, Q96SL3, Q9NRT4, Q9NT32, Q9NVD5	Gene names	CHFR
Domain Architecture
Description	Ubiquitin-protein ligase CHFR (EC 6.3.2.-) (Checkpoint with forkhead and RING finger domains protein).

PTN23_HUMAN
NC score	0.001411 (rank : 200)	θ value	3.0926 (rank : 172)
Query Neighborhood Hits	223	Target Neighborhood Hits	646	Shared Neighborhood Hits	24
SwissProt Accessions	Q9H3S7, Q7KZF8, Q8N6Z5, Q9BSR5, Q9P257, Q9UG03, Q9UMZ4	Gene names	PTPN23, KIAA1471
Domain Architecture	No domain graphic available
Description	Tyrosine-protein phosphatase non-receptor type 23 (EC 3.1.3.48) (His- domain-containing protein tyrosine phosphatase) (HD-PTP) (Protein tyrosine phosphatase TD14) (PTP-TD14).

PKHA6_MOUSE
NC score	0.001385 (rank : 201)	θ value	8.99809 (rank : 217)
Query Neighborhood Hits	223	Target Neighborhood Hits	591	Shared Neighborhood Hits	15
SwissProt Accessions	Q7TQG1, Q8K0J5	Gene names	Plekha6, Pepp3
Domain Architecture
Description	Pleckstrin homology domain-containing family A member 6 (Phosphoinositol 3-phosphate-binding protein 3) (PEPP-3).

CUTL2_HUMAN
NC score	0.000736 (rank : 202)	θ value	2.36792 (rank : 158)
Query Neighborhood Hits	223	Target Neighborhood Hits	906	Shared Neighborhood Hits	25
SwissProt Accessions	O14529	Gene names	CUTL2, KIAA0293
Domain Architecture	No domain graphic available
Description	Homeobox protein cut-like 2 (Homeobox protein Cux-2) (Cut-like 2).

3BP1_HUMAN
NC score	0.000285 (rank : 203)	θ value	8.99809 (rank : 209)
Query Neighborhood Hits	223	Target Neighborhood Hits	376	Shared Neighborhood Hits	15
SwissProt Accessions	Q9Y3L3, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9	Gene names	SH3BP1
Domain Architecture
Description	SH3 domain-binding protein 1 (3BP-1).

MMP9_MOUSE
NC score	0.000085 (rank : 204)	θ value	5.27518 (rank : 196)
Query Neighborhood Hits	223	Target Neighborhood Hits	151	Shared Neighborhood Hits	6
SwissProt Accessions	P41245, Q06788, Q9DC02	Gene names	Mmp9, Clg4b
Domain Architecture
Description	Matrix metalloproteinase-9 precursor (EC 3.4.24.35) (MMP-9) (92 kDa type IV collagenase) (92 kDa gelatinase) (Gelatinase B) (GELB).

CSKI2_MOUSE
NC score	0.000082 (rank : 205)	θ value	1.06291 (rank : 130)
Query Neighborhood Hits	223	Target Neighborhood Hits	812	Shared Neighborhood Hits	38
SwissProt Accessions	Q8VHK1, Q6ZPX1, Q7TS77	Gene names	Caskin2, Kiaa1139
Domain Architecture	No domain graphic available
Description	Caskin-2.

TCRG1_HUMAN
NC score	-0.000037 (rank : 206)	θ value	5.27518 (rank : 201)
Query Neighborhood Hits	223	Target Neighborhood Hits	929	Shared Neighborhood Hits	28
SwissProt Accessions	O14776	Gene names	TCERG1, CA150, TAF2S
Domain Architecture	No domain graphic available
Description	Transcription elongation regulator 1 (TATA box-binding protein- associated factor 2S) (Transcription factor CA150).

SNTB2_HUMAN
NC score	-0.000449 (rank : 207)	θ value	5.27518 (rank : 199)
Query Neighborhood Hits	223	Target Neighborhood Hits	180	Shared Neighborhood Hits	3
SwissProt Accessions	Q13425, Q9BY09	Gene names	SNTB2, SNT2B2
Domain Architecture
Description	Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin 3) (SNT3) (Syntrophin-like) (SNTL).

CNTRB_MOUSE
NC score	-0.000781 (rank : 208)	θ value	1.06291 (rank : 128)
Query Neighborhood Hits	223	Target Neighborhood Hits	1029	Shared Neighborhood Hits	23
SwissProt Accessions	Q8CB62, Q5NCF3	Gene names	Cntrob, Lip8
Domain Architecture	No domain graphic available
Description	Centrobin (LYST-interacting protein 8).

ROBO4_MOUSE
NC score	-0.001059 (rank : 209)	θ value	2.36792 (rank : 160)
Query Neighborhood Hits	223	Target Neighborhood Hits	358	Shared Neighborhood Hits	5
SwissProt Accessions	Q8C310, Q9DBW1	Gene names	Robo4
Domain Architecture
Description	Roundabout homolog 4 precursor.

PRDM2_HUMAN
NC score	-0.001104 (rank : 210)	θ value	0.163984 (rank : 106)
Query Neighborhood Hits	223	Target Neighborhood Hits	1135	Shared Neighborhood Hits	27
SwissProt Accessions	Q13029, Q13149, Q14550, Q5VUL9	Gene names	PRDM2, RIZ
Domain Architecture
Description	PR domain zinc finger protein 2 (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc-finger protein) (Zinc finger protein RIZ) (MTE-binding protein) (MTB-ZF) (GATA-3-binding protein G3B).

WNK4_HUMAN
NC score	-0.002236 (rank : 211)	θ value	0.0431538 (rank : 103)
Query Neighborhood Hits	223	Target Neighborhood Hits	1043	Shared Neighborhood Hits	22
SwissProt Accessions	Q96J92, Q8N8X3, Q8N8Z2, Q96DT8, Q9BYS5	Gene names	WNK4, PRKWNK4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

GLIS1_MOUSE
NC score	-0.003735 (rank : 212)	θ value	0.0961366 (rank : 104)
Query Neighborhood Hits	223	Target Neighborhood Hits	751	Shared Neighborhood Hits	9
SwissProt Accessions	Q8K1M4, Q6NZF6, Q8R4Z3	Gene names	Glis1, Gli5
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLIS1 (GLI-similar 1) (Gli homologous protein 1) (GliH1).

AATK_HUMAN
NC score	-0.004759 (rank : 213)	θ value	0.62314 (rank : 117)
Query Neighborhood Hits	223	Target Neighborhood Hits	1243	Shared Neighborhood Hits	44
SwissProt Accessions	Q6ZMQ8, O75136, Q6ZN31, Q86X28	Gene names	AATK, KIAA0641
Domain Architecture	No domain graphic available
Description	Apoptosis-associated tyrosine-protein kinase (EC 2.7.10.2) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (p35-binding protein) (p35BP).

ASPP1_HUMAN
NC score	-0.004785 (rank : 214)	θ value	8.99809 (rank : 210)
Query Neighborhood Hits	223	Target Neighborhood Hits	956	Shared Neighborhood Hits	19
SwissProt Accessions	Q96KQ4, O94870	Gene names	PPP1R13B, ASPP1, KIAA0771
Domain Architecture
Description	Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B).

WNK1_HUMAN
NC score	-0.004823 (rank : 215)	θ value	4.03905 (rank : 191)
Query Neighborhood Hits	223	Target Neighborhood Hits	1158	Shared Neighborhood Hits	35
SwissProt Accessions	Q9H4A3, O15052, Q86WL5, Q8N673, Q9P1S9	Gene names	WNK1, KDP, KIAA0344, PRKWNK1
Domain Architecture
Description	Serine/threonine-protein kinase WNK1 (EC 2.7.11.1) (Protein kinase with no lysine 1) (Protein kinase, lysine-deficient 1) (Kinase deficient protein).

GLIS1_HUMAN
NC score	-0.005573 (rank : 216)	θ value	0.813845 (rank : 122)
Query Neighborhood Hits	223	Target Neighborhood Hits	748	Shared Neighborhood Hits	9
SwissProt Accessions	Q8NBF1, Q8N9V9	Gene names	GLIS1
Domain Architecture	No domain graphic available
Description	Zinc finger protein GLIS1 (GLI-similar 1).

NOTC3_MOUSE
NC score	-0.006238 (rank : 217)	θ value	4.03905 (rank : 181)
Query Neighborhood Hits	223	Target Neighborhood Hits	975	Shared Neighborhood Hits	12
SwissProt Accessions	Q61982	Gene names	Notch3
Domain Architecture
Description	Neurogenic locus notch homolog protein 3 precursor (Notch 3) [Contains: Notch 3 extracellular truncation; Notch 3 intracellular domain].

ZBTB3_MOUSE
NC score	-0.006466 (rank : 218)	θ value	1.81305 (rank : 156)
Query Neighborhood Hits	223	Target Neighborhood Hits	792	Shared Neighborhood Hits	7
SwissProt Accessions	Q91X45, Q8BIJ4	Gene names	Zbtb3
Domain Architecture
Description	Zinc finger and BTB domain-containing protein 3.

KPCD1_HUMAN
NC score	-0.007601 (rank : 219)	θ value	3.0926 (rank : 168)
Query Neighborhood Hits	223	Target Neighborhood Hits	901	Shared Neighborhood Hits	9
SwissProt Accessions	Q15139	Gene names	PRKD1, PKD, PKD1, PRKCM
Domain Architecture
Description	Serine/threonine-protein kinase D1 (EC 2.7.11.13) (nPKC-D1) (Protein kinase D) (Protein kinase C mu type) (nPKC-mu).

KS6B2_MOUSE
NC score	-0.007781 (rank : 220)	θ value	1.38821 (rank : 146)
Query Neighborhood Hits	223	Target Neighborhood Hits	871	Shared Neighborhood Hits	10
SwissProt Accessions	Q9Z1M4	Gene names	Rps6kb2
Domain Architecture
Description	Ribosomal protein S6 kinase beta-2 (EC 2.7.11.1) (S6K-beta 2) (70 kDa ribosomal protein S6 kinase 2) (p70-S6KB) (p70 ribosomal S6 kinase beta) (p70 S6Kbeta) (S6K2).

ZFP28_HUMAN
NC score	-0.007994 (rank : 221)	θ value	8.99809 (rank : 223)
Query Neighborhood Hits	223	Target Neighborhood Hits	843	Shared Neighborhood Hits	13
SwissProt Accessions	Q8NHY6, Q9BY30, Q9P2B6	Gene names	ZFP28, KIAA1431
Domain Architecture
Description	Zinc finger protein 28 homolog (Zfp-28) (Krueppel-like zinc finger factor X6).

NEK3_MOUSE
NC score	-0.008454 (rank : 222)	θ value	8.99809 (rank : 216)
Query Neighborhood Hits	223	Target Neighborhood Hits	854	Shared Neighborhood Hits	9
SwissProt Accessions	Q9R0A5, Q9Z0X9	Gene names	Nek3
Domain Architecture
Description	Serine/threonine-protein kinase Nek3 (EC 2.7.11.1) (NimA-related protein kinase 3).

BRSK1_HUMAN
NC score	-0.008528 (rank : 223)	θ value	6.88961 (rank : 204)
Query Neighborhood Hits	223	Target Neighborhood Hits	942	Shared Neighborhood Hits	11
SwissProt Accessions	Q8TDC3, Q5J5B5, Q8NDD0, Q8NDR4, Q8TDC2, Q96AV4, Q96JL4	Gene names	BRSK1, KIAA1811, SAD1
Domain Architecture
Description	BR serine/threonine-protein kinase 1 (EC 2.7.11.1) (SAD1 kinase) (SAD1A).