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Network neighborhood for query Sequence : FRS2_HUMAN

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FRS2_HUMAN
SwissProt Accessions	Q8WU20, O43558, Q7LDQ6	Gene names	FRS2
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor substrate 2 (FGFR substrate 2) (Suc1-associated neurotrophic factor target 1) (SNT-1) (FGFR signaling adaptor SNT).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

FRS2_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	40	Target Neighborhood Hits	40	Shared Neighborhood Hits	40
SwissProt Accessions	Q8WU20, O43558, Q7LDQ6	Gene names	FRS2
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor substrate 2 (FGFR substrate 2) (Suc1-associated neurotrophic factor target 1) (SNT-1) (FGFR signaling adaptor SNT).

FRS2_MOUSE
θ value	0 (rank : 2)	NC score	0.996286 (rank : 2)
Query Neighborhood Hits	40	Target Neighborhood Hits	41	Shared Neighborhood Hits	25
SwissProt Accessions	Q8C180	Gene names	Frs2, Frs2a
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor substrate 2 (FGFR substrate 2) (Suc1-associated neurotrophic factor target 1) (SNT-1) (FGFR signaling adaptor SNT) (FRS2 alpha).

FRS3_HUMAN
θ value	4.92331e-123 (rank : 3)	NC score	0.952806 (rank : 3)
Query Neighborhood Hits	40	Target Neighborhood Hits	76	Shared Neighborhood Hits	17
SwissProt Accessions	O43559, Q5T3D5	Gene names	FRS3
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor substrate 3 (FGFR substrate 3) (Suc1-associated neurotrophic factor target 2) (SNT-2) (FGFR signaling adaptor SNT2).

FRS3_MOUSE
θ value	1.63895e-118 (rank : 4)	NC score	0.925237 (rank : 4)
Query Neighborhood Hits	40	Target Neighborhood Hits	168	Shared Neighborhood Hits	19
SwissProt Accessions	Q91WJ0	Gene names	Frs3, Frs2b
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor substrate 3 (FGFR substrate 3) (FRS2-beta).

DOK1_HUMAN
θ value	8.11959e-09 (rank : 5)	NC score	0.492575 (rank : 5)
Query Neighborhood Hits	40	Target Neighborhood Hits	85	Shared Neighborhood Hits	18
SwissProt Accessions	Q99704, O43204, Q9UHG6	Gene names	DOK1
Domain Architecture
Description	Docking protein 1 (Downstream of tyrosine kinase 1) (p62(dok)) (pp62).

DOK1_MOUSE
θ value	1.17247e-07 (rank : 6)	NC score	0.491116 (rank : 6)
Query Neighborhood Hits	40	Target Neighborhood Hits	82	Shared Neighborhood Hits	17
SwissProt Accessions	P97465, Q9R213	Gene names	Dok1, Dok
Domain Architecture
Description	Docking protein 1 (Downstream of tyrosine kinase 1) (p62(dok)).

DOK3_MOUSE
θ value	1.17247e-07 (rank : 7)	NC score	0.490814 (rank : 7)
Query Neighborhood Hits	40	Target Neighborhood Hits	25	Shared Neighborhood Hits	18
SwissProt Accessions	Q9QZK7	Gene names	Dok3, Dokl
Domain Architecture	No domain graphic available
Description	Docking protein 3 (Downstream of tyrosine kinase 3) (P62(dok)-like protein) (DOK-L).

DOK6_HUMAN
θ value	2.61198e-07 (rank : 8)	NC score	0.453102 (rank : 10)
Query Neighborhood Hits	40	Target Neighborhood Hits	25	Shared Neighborhood Hits	19
SwissProt Accessions	Q6PKX4, Q4V9S3, Q8WUZ8, Q96HI2, Q96LU2	Gene names	DOK6, DOK5L
Domain Architecture	No domain graphic available
Description	Docking protein 6 (Downstream of tyrosine kinase 6).

DOK2_MOUSE
θ value	3.41135e-07 (rank : 9)	NC score	0.449652 (rank : 11)
Query Neighborhood Hits	40	Target Neighborhood Hits	244	Shared Neighborhood Hits	19
SwissProt Accessions	O70469, O70272, Q99KL1	Gene names	Dok2, Frip
Domain Architecture
Description	Docking protein 2 (Downstream of tyrosine kinase 2) (p56(dok-2)) (Dok- related protein) (Dok-R) (IL-four receptor-interacting protein) (FRIP).

DOK2_HUMAN
θ value	1.69304e-06 (rank : 10)	NC score	0.480450 (rank : 8)
Query Neighborhood Hits	40	Target Neighborhood Hits	46	Shared Neighborhood Hits	17
SwissProt Accessions	O60496	Gene names	DOK2
Domain Architecture
Description	Docking protein 2 (Downstream of tyrosine kinase 2) (p56(dok-2)).

DOK3_HUMAN
θ value	3.77169e-06 (rank : 11)	NC score	0.469721 (rank : 9)
Query Neighborhood Hits	40	Target Neighborhood Hits	60	Shared Neighborhood Hits	17
SwissProt Accessions	Q7L591, Q8N864, Q9BQB3, Q9H666	Gene names	DOK3
Domain Architecture	No domain graphic available
Description	Docking protein 3 (Downstream of tyrosine kinase 3).

DOK5_HUMAN
θ value	6.43352e-06 (rank : 12)	NC score	0.428753 (rank : 12)
Query Neighborhood Hits	40	Target Neighborhood Hits	28	Shared Neighborhood Hits	19
SwissProt Accessions	Q9P104, Q5T7Y0, Q5TE53, Q8TEW7, Q96H13, Q9BZ24, Q9NQF4, Q9Y411	Gene names	DOK5, C20orf180
Domain Architecture
Description	Docking protein 5 (Downstream of tyrosine kinase 5) (IRS6) (Protein dok-5).

DOK5_MOUSE
θ value	6.43352e-06 (rank : 13)	NC score	0.427509 (rank : 13)
Query Neighborhood Hits	40	Target Neighborhood Hits	27	Shared Neighborhood Hits	19
SwissProt Accessions	Q91ZM9, Q8BRI3, Q9CSM6	Gene names	Dok5
Domain Architecture
Description	Docking protein 5 (Downstream of tyrosine kinase 5) (Protein dok-5).

DOK4_HUMAN
θ value	8.40245e-06 (rank : 14)	NC score	0.423919 (rank : 14)
Query Neighborhood Hits	40	Target Neighborhood Hits	28	Shared Neighborhood Hits	19
SwissProt Accessions	Q8TEW6, O75209, Q9BTP2, Q9NVV3	Gene names	DOK4
Domain Architecture	No domain graphic available
Description	Docking protein 4 (Downstream of tyrosine kinase 4).

DOK4_MOUSE
θ value	1.87187e-05 (rank : 15)	NC score	0.421274 (rank : 15)
Query Neighborhood Hits	40	Target Neighborhood Hits	30	Shared Neighborhood Hits	19
SwissProt Accessions	Q99KE3, Q3U0X3	Gene names	Dok4
Domain Architecture	No domain graphic available
Description	Docking protein 4 (Downstream of tyrosine kinase 4).

DOK7_MOUSE
θ value	0.125558 (rank : 16)	NC score	0.197260 (rank : 17)
Query Neighborhood Hits	40	Target Neighborhood Hits	169	Shared Neighborhood Hits	17
SwissProt Accessions	Q18PE0, Q3TCZ6, Q5FW70, Q8C8U7	Gene names	Dok7
Domain Architecture	No domain graphic available
Description	Protein Dok-7 (Downstream of tyrosine kinase 7).

DOK7_HUMAN
θ value	0.365318 (rank : 17)	NC score	0.208630 (rank : 16)
Query Neighborhood Hits	40	Target Neighborhood Hits	51	Shared Neighborhood Hits	17
SwissProt Accessions	Q18PE1, Q6P6A6, Q86XG5, Q8N2J3, Q8NBC1	Gene names	DOK7, C4orf25
Domain Architecture	No domain graphic available
Description	Protein Dok-7 (Downstream of tyrosine kinase 7).

BRE1B_HUMAN
θ value	1.06291 (rank : 18)	NC score	0.014994 (rank : 30)
Query Neighborhood Hits	40	Target Neighborhood Hits	1040	Shared Neighborhood Hits	6
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

MYRIP_MOUSE
θ value	1.81305 (rank : 19)	NC score	0.021135 (rank : 26)
Query Neighborhood Hits	40	Target Neighborhood Hits	207	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K3I4, Q8CFC0, Q8K4H5	Gene names	Myrip, Slac2c
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

RTN1_HUMAN
θ value	1.81305 (rank : 20)	NC score	0.024512 (rank : 23)
Query Neighborhood Hits	40	Target Neighborhood Hits	173	Shared Neighborhood Hits	3
SwissProt Accessions	Q16799, Q16800, Q16801	Gene names	RTN1, NSP
Domain Architecture
Description	Reticulon-1 (Neuroendocrine-specific protein).

OGFR_MOUSE
θ value	3.0926 (rank : 21)	NC score	0.018902 (rank : 28)
Query Neighborhood Hits	40	Target Neighborhood Hits	584	Shared Neighborhood Hits	3
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

K0310_HUMAN
θ value	4.03905 (rank : 22)	NC score	0.022440 (rank : 24)
Query Neighborhood Hits	40	Target Neighborhood Hits	420	Shared Neighborhood Hits	6
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

KI13A_HUMAN
θ value	4.03905 (rank : 23)	NC score	0.008539 (rank : 35)
Query Neighborhood Hits	40	Target Neighborhood Hits	359	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H1H9, Q9H1H8	Gene names	KIF13A, RBKIN
Domain Architecture
Description	Kinesin-like protein KIF13A (Kinesin-like protein RBKIN).

BPTF_HUMAN
θ value	5.27518 (rank : 24)	NC score	0.007548 (rank : 38)
Query Neighborhood Hits	40	Target Neighborhood Hits	786	Shared Neighborhood Hits	2
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

ES8L1_MOUSE
θ value	5.27518 (rank : 25)	NC score	0.009572 (rank : 33)
Query Neighborhood Hits	40	Target Neighborhood Hits	143	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R5F8, Q8R0D6, Q9D2M6	Gene names	Eps8l1, Eps8r1
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 1 (Epidermal growth factor receptor pathway substrate 8-related protein 1) (EPS8-like protein 1).

FANCM_MOUSE
θ value	5.27518 (rank : 26)	NC score	0.011774 (rank : 31)
Query Neighborhood Hits	40	Target Neighborhood Hits	177	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BGE5, Q69ZF5, Q8BKB7, Q8BUA8	Gene names	Fancm, Kiaa1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein homolog (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM).

HIP1R_HUMAN
θ value	5.27518 (rank : 27)	NC score	0.009504 (rank : 34)
Query Neighborhood Hits	40	Target Neighborhood Hits	809	Shared Neighborhood Hits	5
SwissProt Accessions	O75146, Q9UED9	Gene names	HIP1R, HIP12, KIAA0655
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related) (Hip 12).

KI13A_MOUSE
θ value	5.27518 (rank : 28)	NC score	0.007997 (rank : 37)
Query Neighborhood Hits	40	Target Neighborhood Hits	395	Shared Neighborhood Hits	3
SwissProt Accessions	Q9EQW7, O35062	Gene names	Kif13a
Domain Architecture
Description	Kinesin-like protein KIF13A.

PAF49_MOUSE
θ value	5.27518 (rank : 29)	NC score	0.019283 (rank : 27)
Query Neighborhood Hits	40	Target Neighborhood Hits	48	Shared Neighborhood Hits	2
SwissProt Accessions	Q76KJ5, Q8K0Y9	Gene names	Cd3eap, Ase1, Paf49
Domain Architecture	No domain graphic available
Description	RNA polymerase I-associated factor PAF49 (Anti-sense to ERCC-1 protein) (ASE-1) (CD3-epsilon-associated protein) (CD3E-associated protein).

IRS1_HUMAN
θ value	6.88961 (rank : 30)	NC score	0.051703 (rank : 20)
Query Neighborhood Hits	40	Target Neighborhood Hits	109	Shared Neighborhood Hits	10
SwissProt Accessions	P35568	Gene names	IRS1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

IRS1_MOUSE
θ value	6.88961 (rank : 31)	NC score	0.060853 (rank : 19)
Query Neighborhood Hits	40	Target Neighborhood Hits	112	Shared Neighborhood Hits	11
SwissProt Accessions	P35569	Gene names	Irs1, Irs-1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

NOL7_HUMAN
θ value	6.88961 (rank : 32)	NC score	0.032018 (rank : 21)
Query Neighborhood Hits	40	Target Neighborhood Hits	39	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UMY1, Q5T297, Q9Y3U7	Gene names	NOL7, C6orf90, NOP27
Domain Architecture	No domain graphic available
Description	Nucleolar protein 7 (Nucleolar protein of 27 kDa).

PEBPL_MOUSE
θ value	6.88961 (rank : 33)	NC score	0.025836 (rank : 22)
Query Neighborhood Hits	40	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D9G2	Gene names
Domain Architecture
Description	PEBP family protein precursor.

TBCD1_HUMAN
θ value	6.88961 (rank : 34)	NC score	0.008072 (rank : 36)
Query Neighborhood Hits	40	Target Neighborhood Hits	276	Shared Neighborhood Hits	2
SwissProt Accessions	Q86TI0, Q96K82, Q9UPP4	Gene names	TBC1D1, KIAA1108
Domain Architecture
Description	TBC1 domain family member 1.

BCL9_MOUSE
θ value	8.99809 (rank : 35)	NC score	0.022320 (rank : 25)
Query Neighborhood Hits	40	Target Neighborhood Hits	770	Shared Neighborhood Hits	6
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

BICD1_HUMAN
θ value	8.99809 (rank : 36)	NC score	0.002973 (rank : 41)
Query Neighborhood Hits	40	Target Neighborhood Hits	844	Shared Neighborhood Hits	6
SwissProt Accessions	Q96G01, O43892, O43893	Gene names	BICD1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.

CQ028_MOUSE
θ value	8.99809 (rank : 37)	NC score	0.010668 (rank : 32)
Query Neighborhood Hits	40	Target Neighborhood Hits	54	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R1F6, Q8C8V6	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C17orf28 homolog.

PDE4A_HUMAN
θ value	8.99809 (rank : 38)	NC score	0.003796 (rank : 40)
Query Neighborhood Hits	40	Target Neighborhood Hits	73	Shared Neighborhood Hits	2
SwissProt Accessions	P27815, O75522, O76092, Q16255, Q16691, Q8WUQ3	Gene names	PDE4A
Domain Architecture
Description	cAMP-specific 3',5'-cyclic phosphodiesterase 4A (EC 3.1.4.17) (DPDE2) (PDE46).

PK1L1_HUMAN
θ value	8.99809 (rank : 39)	NC score	0.016421 (rank : 29)
Query Neighborhood Hits	40	Target Neighborhood Hits	140	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TDX9, Q6UWK1	Gene names	PKD1L1
Domain Architecture
Description	Polycystic kidney disease 1-like 1 protein (Polycystin-1L1).

VMD2_MOUSE
θ value	8.99809 (rank : 40)	NC score	0.007266 (rank : 39)
Query Neighborhood Hits	40	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	O88870, Q6H1V0	Gene names	Vmd2, Bmd1
Domain Architecture	No domain graphic available
Description	Bestrophin-1 (Vitelliform macular dystrophy protein 2 homolog).

PRPE_HUMAN
θ value	θ > 10 (rank : 41)	NC score	0.067835 (rank : 18)
Query Neighborhood Hits	40	Target Neighborhood Hits	44	Shared Neighborhood Hits	1
SwissProt Accessions	P02811	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide P-E (IB-9).

Hits sorted by NC score

FRS2_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	40	Target Neighborhood Hits	40	Shared Neighborhood Hits	40
SwissProt Accessions	Q8WU20, O43558, Q7LDQ6	Gene names	FRS2
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor substrate 2 (FGFR substrate 2) (Suc1-associated neurotrophic factor target 1) (SNT-1) (FGFR signaling adaptor SNT).

FRS2_MOUSE
NC score	0.996286 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	40	Target Neighborhood Hits	41	Shared Neighborhood Hits	25
SwissProt Accessions	Q8C180	Gene names	Frs2, Frs2a
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor substrate 2 (FGFR substrate 2) (Suc1-associated neurotrophic factor target 1) (SNT-1) (FGFR signaling adaptor SNT) (FRS2 alpha).

FRS3_HUMAN
NC score	0.952806 (rank : 3)	θ value	4.92331e-123 (rank : 3)
Query Neighborhood Hits	40	Target Neighborhood Hits	76	Shared Neighborhood Hits	17
SwissProt Accessions	O43559, Q5T3D5	Gene names	FRS3
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor substrate 3 (FGFR substrate 3) (Suc1-associated neurotrophic factor target 2) (SNT-2) (FGFR signaling adaptor SNT2).

FRS3_MOUSE
NC score	0.925237 (rank : 4)	θ value	1.63895e-118 (rank : 4)
Query Neighborhood Hits	40	Target Neighborhood Hits	168	Shared Neighborhood Hits	19
SwissProt Accessions	Q91WJ0	Gene names	Frs3, Frs2b
Domain Architecture	No domain graphic available
Description	Fibroblast growth factor receptor substrate 3 (FGFR substrate 3) (FRS2-beta).

DOK1_HUMAN
NC score	0.492575 (rank : 5)	θ value	8.11959e-09 (rank : 5)
Query Neighborhood Hits	40	Target Neighborhood Hits	85	Shared Neighborhood Hits	18
SwissProt Accessions	Q99704, O43204, Q9UHG6	Gene names	DOK1
Domain Architecture
Description	Docking protein 1 (Downstream of tyrosine kinase 1) (p62(dok)) (pp62).

DOK1_MOUSE
NC score	0.491116 (rank : 6)	θ value	1.17247e-07 (rank : 6)
Query Neighborhood Hits	40	Target Neighborhood Hits	82	Shared Neighborhood Hits	17
SwissProt Accessions	P97465, Q9R213	Gene names	Dok1, Dok
Domain Architecture
Description	Docking protein 1 (Downstream of tyrosine kinase 1) (p62(dok)).

DOK3_MOUSE
NC score	0.490814 (rank : 7)	θ value	1.17247e-07 (rank : 7)
Query Neighborhood Hits	40	Target Neighborhood Hits	25	Shared Neighborhood Hits	18
SwissProt Accessions	Q9QZK7	Gene names	Dok3, Dokl
Domain Architecture	No domain graphic available
Description	Docking protein 3 (Downstream of tyrosine kinase 3) (P62(dok)-like protein) (DOK-L).

DOK2_HUMAN
NC score	0.480450 (rank : 8)	θ value	1.69304e-06 (rank : 10)
Query Neighborhood Hits	40	Target Neighborhood Hits	46	Shared Neighborhood Hits	17
SwissProt Accessions	O60496	Gene names	DOK2
Domain Architecture
Description	Docking protein 2 (Downstream of tyrosine kinase 2) (p56(dok-2)).

DOK3_HUMAN
NC score	0.469721 (rank : 9)	θ value	3.77169e-06 (rank : 11)
Query Neighborhood Hits	40	Target Neighborhood Hits	60	Shared Neighborhood Hits	17
SwissProt Accessions	Q7L591, Q8N864, Q9BQB3, Q9H666	Gene names	DOK3
Domain Architecture	No domain graphic available
Description	Docking protein 3 (Downstream of tyrosine kinase 3).

DOK6_HUMAN
NC score	0.453102 (rank : 10)	θ value	2.61198e-07 (rank : 8)
Query Neighborhood Hits	40	Target Neighborhood Hits	25	Shared Neighborhood Hits	19
SwissProt Accessions	Q6PKX4, Q4V9S3, Q8WUZ8, Q96HI2, Q96LU2	Gene names	DOK6, DOK5L
Domain Architecture	No domain graphic available
Description	Docking protein 6 (Downstream of tyrosine kinase 6).

DOK2_MOUSE
NC score	0.449652 (rank : 11)	θ value	3.41135e-07 (rank : 9)
Query Neighborhood Hits	40	Target Neighborhood Hits	244	Shared Neighborhood Hits	19
SwissProt Accessions	O70469, O70272, Q99KL1	Gene names	Dok2, Frip
Domain Architecture
Description	Docking protein 2 (Downstream of tyrosine kinase 2) (p56(dok-2)) (Dok- related protein) (Dok-R) (IL-four receptor-interacting protein) (FRIP).

DOK5_HUMAN
NC score	0.428753 (rank : 12)	θ value	6.43352e-06 (rank : 12)
Query Neighborhood Hits	40	Target Neighborhood Hits	28	Shared Neighborhood Hits	19
SwissProt Accessions	Q9P104, Q5T7Y0, Q5TE53, Q8TEW7, Q96H13, Q9BZ24, Q9NQF4, Q9Y411	Gene names	DOK5, C20orf180
Domain Architecture
Description	Docking protein 5 (Downstream of tyrosine kinase 5) (IRS6) (Protein dok-5).

DOK5_MOUSE
NC score	0.427509 (rank : 13)	θ value	6.43352e-06 (rank : 13)
Query Neighborhood Hits	40	Target Neighborhood Hits	27	Shared Neighborhood Hits	19
SwissProt Accessions	Q91ZM9, Q8BRI3, Q9CSM6	Gene names	Dok5
Domain Architecture
Description	Docking protein 5 (Downstream of tyrosine kinase 5) (Protein dok-5).

DOK4_HUMAN
NC score	0.423919 (rank : 14)	θ value	8.40245e-06 (rank : 14)
Query Neighborhood Hits	40	Target Neighborhood Hits	28	Shared Neighborhood Hits	19
SwissProt Accessions	Q8TEW6, O75209, Q9BTP2, Q9NVV3	Gene names	DOK4
Domain Architecture	No domain graphic available
Description	Docking protein 4 (Downstream of tyrosine kinase 4).

DOK4_MOUSE
NC score	0.421274 (rank : 15)	θ value	1.87187e-05 (rank : 15)
Query Neighborhood Hits	40	Target Neighborhood Hits	30	Shared Neighborhood Hits	19
SwissProt Accessions	Q99KE3, Q3U0X3	Gene names	Dok4
Domain Architecture	No domain graphic available
Description	Docking protein 4 (Downstream of tyrosine kinase 4).

DOK7_HUMAN
NC score	0.208630 (rank : 16)	θ value	0.365318 (rank : 17)
Query Neighborhood Hits	40	Target Neighborhood Hits	51	Shared Neighborhood Hits	17
SwissProt Accessions	Q18PE1, Q6P6A6, Q86XG5, Q8N2J3, Q8NBC1	Gene names	DOK7, C4orf25
Domain Architecture	No domain graphic available
Description	Protein Dok-7 (Downstream of tyrosine kinase 7).

DOK7_MOUSE
NC score	0.197260 (rank : 17)	θ value	0.125558 (rank : 16)
Query Neighborhood Hits	40	Target Neighborhood Hits	169	Shared Neighborhood Hits	17
SwissProt Accessions	Q18PE0, Q3TCZ6, Q5FW70, Q8C8U7	Gene names	Dok7
Domain Architecture	No domain graphic available
Description	Protein Dok-7 (Downstream of tyrosine kinase 7).

PRPE_HUMAN
NC score	0.067835 (rank : 18)	θ value	θ > 10 (rank : 41)
Query Neighborhood Hits	40	Target Neighborhood Hits	44	Shared Neighborhood Hits	1
SwissProt Accessions	P02811	Gene names
Domain Architecture	No domain graphic available
Description	Basic proline-rich peptide P-E (IB-9).

IRS1_MOUSE
NC score	0.060853 (rank : 19)	θ value	6.88961 (rank : 31)
Query Neighborhood Hits	40	Target Neighborhood Hits	112	Shared Neighborhood Hits	11
SwissProt Accessions	P35569	Gene names	Irs1, Irs-1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

IRS1_HUMAN
NC score	0.051703 (rank : 20)	θ value	6.88961 (rank : 30)
Query Neighborhood Hits	40	Target Neighborhood Hits	109	Shared Neighborhood Hits	10
SwissProt Accessions	P35568	Gene names	IRS1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

NOL7_HUMAN
NC score	0.032018 (rank : 21)	θ value	6.88961 (rank : 32)
Query Neighborhood Hits	40	Target Neighborhood Hits	39	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UMY1, Q5T297, Q9Y3U7	Gene names	NOL7, C6orf90, NOP27
Domain Architecture	No domain graphic available
Description	Nucleolar protein 7 (Nucleolar protein of 27 kDa).

PEBPL_MOUSE
NC score	0.025836 (rank : 22)	θ value	6.88961 (rank : 33)
Query Neighborhood Hits	40	Target Neighborhood Hits	8	Shared Neighborhood Hits	3
SwissProt Accessions	Q9D9G2	Gene names
Domain Architecture
Description	PEBP family protein precursor.

RTN1_HUMAN
NC score	0.024512 (rank : 23)	θ value	1.81305 (rank : 20)
Query Neighborhood Hits	40	Target Neighborhood Hits	173	Shared Neighborhood Hits	3
SwissProt Accessions	Q16799, Q16800, Q16801	Gene names	RTN1, NSP
Domain Architecture
Description	Reticulon-1 (Neuroendocrine-specific protein).

K0310_HUMAN
NC score	0.022440 (rank : 24)	θ value	4.03905 (rank : 22)
Query Neighborhood Hits	40	Target Neighborhood Hits	420	Shared Neighborhood Hits	6
SwissProt Accessions	O15027, Q5SXP0, Q5SXP1, Q8N347, Q96HP1	Gene names	KIAA0310
Domain Architecture	No domain graphic available
Description	Protein KIAA0310.

BCL9_MOUSE
NC score	0.022320 (rank : 25)	θ value	8.99809 (rank : 35)
Query Neighborhood Hits	40	Target Neighborhood Hits	770	Shared Neighborhood Hits	6
SwissProt Accessions	Q9D219, Q67FX9, Q8BUJ8, Q8VE74	Gene names	Bcl9
Domain Architecture	No domain graphic available
Description	B-cell lymphoma 9 protein (Bcl-9).

MYRIP_MOUSE
NC score	0.021135 (rank : 26)	θ value	1.81305 (rank : 19)
Query Neighborhood Hits	40	Target Neighborhood Hits	207	Shared Neighborhood Hits	3
SwissProt Accessions	Q8K3I4, Q8CFC0, Q8K4H5	Gene names	Myrip, Slac2c
Domain Architecture
Description	Rab effector MyRIP (Myosin-VIIa- and Rab-interacting protein) (Exophilin-8) (Slp homolog lacking C2 domains c).

PAF49_MOUSE
NC score	0.019283 (rank : 27)	θ value	5.27518 (rank : 29)
Query Neighborhood Hits	40	Target Neighborhood Hits	48	Shared Neighborhood Hits	2
SwissProt Accessions	Q76KJ5, Q8K0Y9	Gene names	Cd3eap, Ase1, Paf49
Domain Architecture	No domain graphic available
Description	RNA polymerase I-associated factor PAF49 (Anti-sense to ERCC-1 protein) (ASE-1) (CD3-epsilon-associated protein) (CD3E-associated protein).

OGFR_MOUSE
NC score	0.018902 (rank : 28)	θ value	3.0926 (rank : 21)
Query Neighborhood Hits	40	Target Neighborhood Hits	584	Shared Neighborhood Hits	3
SwissProt Accessions	Q99PG2, Q99L33	Gene names	Ogfr
Domain Architecture
Description	Opioid growth factor receptor (OGFr) (Zeta-type opioid receptor).

PK1L1_HUMAN
NC score	0.016421 (rank : 29)	θ value	8.99809 (rank : 39)
Query Neighborhood Hits	40	Target Neighborhood Hits	140	Shared Neighborhood Hits	3
SwissProt Accessions	Q8TDX9, Q6UWK1	Gene names	PKD1L1
Domain Architecture
Description	Polycystic kidney disease 1-like 1 protein (Polycystin-1L1).

BRE1B_HUMAN
NC score	0.014994 (rank : 30)	θ value	1.06291 (rank : 18)
Query Neighborhood Hits	40	Target Neighborhood Hits	1040	Shared Neighborhood Hits	6
SwissProt Accessions	O75150, Q6AHZ6, Q6N005, Q7L3T6, Q8N615, Q96T18, Q9BSV9, Q9HC82	Gene names	RNF40, BRE1B, KIAA0661
Domain Architecture	No domain graphic available
Description	Ubiquitin-protein ligase BRE1B (EC 6.3.2.-) (BRE1-B) (RING finger protein 40) (95 kDa retinoblastoma-associated protein) (RBP95).

FANCM_MOUSE
NC score	0.011774 (rank : 31)	θ value	5.27518 (rank : 26)
Query Neighborhood Hits	40	Target Neighborhood Hits	177	Shared Neighborhood Hits	2
SwissProt Accessions	Q8BGE5, Q69ZF5, Q8BKB7, Q8BUA8	Gene names	Fancm, Kiaa1596
Domain Architecture	No domain graphic available
Description	Fanconi anemia group M protein homolog (EC 3.6.1.-) (ATP-dependent RNA helicase FANCM) (Protein FACM).

CQ028_MOUSE
NC score	0.010668 (rank : 32)	θ value	8.99809 (rank : 37)
Query Neighborhood Hits	40	Target Neighborhood Hits	54	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R1F6, Q8C8V6	Gene names
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C17orf28 homolog.

ES8L1_MOUSE
NC score	0.009572 (rank : 33)	θ value	5.27518 (rank : 25)
Query Neighborhood Hits	40	Target Neighborhood Hits	143	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R5F8, Q8R0D6, Q9D2M6	Gene names	Eps8l1, Eps8r1
Domain Architecture	No domain graphic available
Description	Epidermal growth factor receptor kinase substrate 8-like protein 1 (Epidermal growth factor receptor pathway substrate 8-related protein 1) (EPS8-like protein 1).

HIP1R_HUMAN
NC score	0.009504 (rank : 34)	θ value	5.27518 (rank : 27)
Query Neighborhood Hits	40	Target Neighborhood Hits	809	Shared Neighborhood Hits	5
SwissProt Accessions	O75146, Q9UED9	Gene names	HIP1R, HIP12, KIAA0655
Domain Architecture
Description	Huntingtin-interacting protein 1-related protein (Hip1-related) (Hip 12).

KI13A_HUMAN
NC score	0.008539 (rank : 35)	θ value	4.03905 (rank : 23)
Query Neighborhood Hits	40	Target Neighborhood Hits	359	Shared Neighborhood Hits	4
SwissProt Accessions	Q9H1H9, Q9H1H8	Gene names	KIF13A, RBKIN
Domain Architecture
Description	Kinesin-like protein KIF13A (Kinesin-like protein RBKIN).

TBCD1_HUMAN
NC score	0.008072 (rank : 36)	θ value	6.88961 (rank : 34)
Query Neighborhood Hits	40	Target Neighborhood Hits	276	Shared Neighborhood Hits	2
SwissProt Accessions	Q86TI0, Q96K82, Q9UPP4	Gene names	TBC1D1, KIAA1108
Domain Architecture
Description	TBC1 domain family member 1.

KI13A_MOUSE
NC score	0.007997 (rank : 37)	θ value	5.27518 (rank : 28)
Query Neighborhood Hits	40	Target Neighborhood Hits	395	Shared Neighborhood Hits	3
SwissProt Accessions	Q9EQW7, O35062	Gene names	Kif13a
Domain Architecture
Description	Kinesin-like protein KIF13A.

BPTF_HUMAN
NC score	0.007548 (rank : 38)	θ value	5.27518 (rank : 24)
Query Neighborhood Hits	40	Target Neighborhood Hits	786	Shared Neighborhood Hits	2
SwissProt Accessions	Q12830, Q6NX67, Q7Z7D6, Q9UIG2	Gene names	FALZ, BPTF, FAC1
Domain Architecture
Description	Nucleosome remodeling factor subunit BPTF (Bromodomain and PHD finger- containing transcription factor) (Fetal Alzheimer antigen) (Fetal Alz- 50 clone 1 protein).

VMD2_MOUSE
NC score	0.007266 (rank : 39)	θ value	8.99809 (rank : 40)
Query Neighborhood Hits	40	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	O88870, Q6H1V0	Gene names	Vmd2, Bmd1
Domain Architecture	No domain graphic available
Description	Bestrophin-1 (Vitelliform macular dystrophy protein 2 homolog).

PDE4A_HUMAN
NC score	0.003796 (rank : 40)	θ value	8.99809 (rank : 38)
Query Neighborhood Hits	40	Target Neighborhood Hits	73	Shared Neighborhood Hits	2
SwissProt Accessions	P27815, O75522, O76092, Q16255, Q16691, Q8WUQ3	Gene names	PDE4A
Domain Architecture
Description	cAMP-specific 3',5'-cyclic phosphodiesterase 4A (EC 3.1.4.17) (DPDE2) (PDE46).

BICD1_HUMAN
NC score	0.002973 (rank : 41)	θ value	8.99809 (rank : 36)
Query Neighborhood Hits	40	Target Neighborhood Hits	844	Shared Neighborhood Hits	6
SwissProt Accessions	Q96G01, O43892, O43893	Gene names	BICD1
Domain Architecture	No domain graphic available
Description	Cytoskeleton-like bicaudal D protein homolog 1.