Please be patient as the page loads

Stop Image Loading/Displaying

Network neighborhood for query Sequence : MUS81_HUMAN

For an explanation of this page, click here

MUS81_HUMAN
SwissProt Accessions	Q96NY9, Q9H7D9	Gene names	MUS81
Domain Architecture
Description	Crossover junction endonuclease MUS81 (EC 3.1.22.-).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

MUS81_HUMAN
θ value	0 (rank : 1)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	21	Target Neighborhood Hits	21	Shared Neighborhood Hits	21
SwissProt Accessions	Q96NY9, Q9H7D9	Gene names	MUS81
Domain Architecture
Description	Crossover junction endonuclease MUS81 (EC 3.1.22.-).

MUS81_MOUSE
θ value	0 (rank : 2)	NC score	0.993650 (rank : 2)
Query Neighborhood Hits	21	Target Neighborhood Hits	12	Shared Neighborhood Hits	5
SwissProt Accessions	Q91ZJ0, Q8R356	Gene names	Mus81
Domain Architecture
Description	Crossover junction endonuclease MUS81 (EC 3.1.22.-).

EME1_MOUSE
θ value	1.69304e-06 (rank : 3)	NC score	0.340597 (rank : 3)
Query Neighborhood Hits	21	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BJW7	Gene names	Eme1
Domain Architecture	No domain graphic available
Description	Crossover junction endonuclease EME1 (EC 3.1.22.-).

EME1_HUMAN
θ value	8.40245e-06 (rank : 4)	NC score	0.325996 (rank : 4)
Query Neighborhood Hits	21	Target Neighborhood Hits	31	Shared Neighborhood Hits	4
SwissProt Accessions	Q96AY2, Q96N62	Gene names	EME1, MMS4
Domain Architecture	No domain graphic available
Description	Crossover junction endonuclease EME1 (EC 3.1.22.-) (hMMS4).

UN45B_HUMAN
θ value	1.06291 (rank : 5)	NC score	0.038755 (rank : 5)
Query Neighborhood Hits	21	Target Neighborhood Hits	97	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IWX7, Q495Q8, Q495Q9	Gene names	UNC45B, CMYA4, UNC45
Domain Architecture	No domain graphic available
Description	UNC45 homolog B (UNC-45B).

UN45B_MOUSE
θ value	1.38821 (rank : 6)	NC score	0.037602 (rank : 6)
Query Neighborhood Hits	21	Target Neighborhood Hits	90	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CGY6, Q5XG72, Q8BHC5, Q8BWK3	Gene names	Unc45b, Cmya4
Domain Architecture	No domain graphic available
Description	UNC45 homolog B (UNC-45B).

MYO5B_HUMAN
θ value	2.36792 (rank : 7)	NC score	0.009591 (rank : 17)
Query Neighborhood Hits	21	Target Neighborhood Hits	911	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ULV0	Gene names	MYO5B, KIAA1119
Domain Architecture
Description	Myosin-5B (Myosin Vb).

HNRPR_HUMAN
θ value	3.0926 (rank : 8)	NC score	0.014267 (rank : 11)
Query Neighborhood Hits	21	Target Neighborhood Hits	240	Shared Neighborhood Hits	2
SwissProt Accessions	O43390	Gene names	HNRPR
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein R (hnRNP R).

IRS1_HUMAN
θ value	3.0926 (rank : 9)	NC score	0.021827 (rank : 7)
Query Neighborhood Hits	21	Target Neighborhood Hits	109	Shared Neighborhood Hits	2
SwissProt Accessions	P35568	Gene names	IRS1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

BSN_MOUSE
θ value	4.03905 (rank : 10)	NC score	0.012242 (rank : 13)
Query Neighborhood Hits	21	Target Neighborhood Hits	2057	Shared Neighborhood Hits	7
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

PHX2A_HUMAN
θ value	4.03905 (rank : 11)	NC score	0.010205 (rank : 15)
Query Neighborhood Hits	21	Target Neighborhood Hits	345	Shared Neighborhood Hits	3
SwissProt Accessions	O14813, Q8IVZ2	Gene names	PHOX2A, ARIX, PMX2A
Domain Architecture
Description	Paired mesoderm homeobox protein 2A (Paired-like homeobox 2A) (Aristaless homeobox protein homolog) (ARIX1 homeodomain protein).

PHX2A_MOUSE
θ value	4.03905 (rank : 12)	NC score	0.010406 (rank : 14)
Query Neighborhood Hits	21	Target Neighborhood Hits	338	Shared Neighborhood Hits	3
SwissProt Accessions	Q62066	Gene names	Phox2a, Arix, Phox2, Pmx2, Pmx2a
Domain Architecture
Description	Paired mesoderm homeobox protein 2A (Paired-like homeobox 2A) (PHOX2A homeodomain protein) (Aristaless homeobox protein homolog).

MYH14_HUMAN
θ value	5.27518 (rank : 13)	NC score	0.008581 (rank : 18)
Query Neighborhood Hits	21	Target Neighborhood Hits	995	Shared Neighborhood Hits	4
SwissProt Accessions	Q7Z406, Q5CZ75, Q6XYE4, Q76B62, Q8WV23, Q96I22, Q9BT27, Q9BW35, Q9H882	Gene names	MYH14, KIAA2034
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

WNK4_HUMAN
θ value	5.27518 (rank : 14)	NC score	0.003781 (rank : 20)
Query Neighborhood Hits	21	Target Neighborhood Hits	1043	Shared Neighborhood Hits	6
SwissProt Accessions	Q96J92, Q8N8X3, Q8N8Z2, Q96DT8, Q9BYS5	Gene names	WNK4, PRKWNK4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

ACK1_HUMAN
θ value	6.88961 (rank : 15)	NC score	0.001975 (rank : 21)
Query Neighborhood Hits	21	Target Neighborhood Hits	1140	Shared Neighborhood Hits	5
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).

B4GN4_HUMAN
θ value	6.88961 (rank : 16)	NC score	0.013761 (rank : 12)
Query Neighborhood Hits	21	Target Neighborhood Hits	131	Shared Neighborhood Hits	3
SwissProt Accessions	Q76KP1, Q96LV2	Gene names	B4GALNT4
Domain Architecture	No domain graphic available
Description	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase 1 (EC 2.4.1.244) (NGalNAc-T1) (Beta- 1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4).

TAF6L_HUMAN
θ value	6.88961 (rank : 17)	NC score	0.017284 (rank : 9)
Query Neighborhood Hits	21	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y6J9, Q96HA6	Gene names	TAF6L, PAF65A
Domain Architecture
Description	TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L (PCAF-associated factor 65 alpha) (PAF65- alpha).

ETV3_HUMAN
θ value	8.99809 (rank : 18)	NC score	0.007425 (rank : 19)
Query Neighborhood Hits	21	Target Neighborhood Hits	312	Shared Neighborhood Hits	3
SwissProt Accessions	P41162, Q8TAC8, Q9BX30	Gene names	ETV3, METS, PE1
Domain Architecture	No domain graphic available
Description	ETS translocation variant 3 (ETS-domain transcriptional repressor PE1) (PE-1) (Mitogenic Ets transcriptional suppressor).

NPAS4_HUMAN
θ value	8.99809 (rank : 19)	NC score	0.016971 (rank : 10)
Query Neighborhood Hits	21	Target Neighborhood Hits	214	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IUM7, Q8N8S5, Q8N9Q9	Gene names	NPAS4, NXF
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF).

NPAS4_MOUSE
θ value	8.99809 (rank : 20)	NC score	0.017617 (rank : 8)
Query Neighborhood Hits	21	Target Neighborhood Hits	245	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BGD7, Q3V3U3	Gene names	Npas4, Nxf
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF) (Limbic-enhanced PAS protein) (LE-PAS).

SCAM3_MOUSE
θ value	8.99809 (rank : 21)	NC score	0.010102 (rank : 16)
Query Neighborhood Hits	21	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	O35609, Q99M48, Q9ERM9	Gene names	Scamp3
Domain Architecture
Description	Secretory carrier-associated membrane protein 3 (Secretory carrier membrane protein 3).

Hits sorted by NC score

MUS81_HUMAN
NC score	0.999962 (rank : 1)	θ value	0 (rank : 1)
Query Neighborhood Hits	21	Target Neighborhood Hits	21	Shared Neighborhood Hits	21
SwissProt Accessions	Q96NY9, Q9H7D9	Gene names	MUS81
Domain Architecture
Description	Crossover junction endonuclease MUS81 (EC 3.1.22.-).

MUS81_MOUSE
NC score	0.993650 (rank : 2)	θ value	0 (rank : 2)
Query Neighborhood Hits	21	Target Neighborhood Hits	12	Shared Neighborhood Hits	5
SwissProt Accessions	Q91ZJ0, Q8R356	Gene names	Mus81
Domain Architecture
Description	Crossover junction endonuclease MUS81 (EC 3.1.22.-).

EME1_MOUSE
NC score	0.340597 (rank : 3)	θ value	1.69304e-06 (rank : 3)
Query Neighborhood Hits	21	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	Q8BJW7	Gene names	Eme1
Domain Architecture	No domain graphic available
Description	Crossover junction endonuclease EME1 (EC 3.1.22.-).

EME1_HUMAN
NC score	0.325996 (rank : 4)	θ value	8.40245e-06 (rank : 4)
Query Neighborhood Hits	21	Target Neighborhood Hits	31	Shared Neighborhood Hits	4
SwissProt Accessions	Q96AY2, Q96N62	Gene names	EME1, MMS4
Domain Architecture	No domain graphic available
Description	Crossover junction endonuclease EME1 (EC 3.1.22.-) (hMMS4).

UN45B_HUMAN
NC score	0.038755 (rank : 5)	θ value	1.06291 (rank : 5)
Query Neighborhood Hits	21	Target Neighborhood Hits	97	Shared Neighborhood Hits	3
SwissProt Accessions	Q8IWX7, Q495Q8, Q495Q9	Gene names	UNC45B, CMYA4, UNC45
Domain Architecture	No domain graphic available
Description	UNC45 homolog B (UNC-45B).

UN45B_MOUSE
NC score	0.037602 (rank : 6)	θ value	1.38821 (rank : 6)
Query Neighborhood Hits	21	Target Neighborhood Hits	90	Shared Neighborhood Hits	3
SwissProt Accessions	Q8CGY6, Q5XG72, Q8BHC5, Q8BWK3	Gene names	Unc45b, Cmya4
Domain Architecture	No domain graphic available
Description	UNC45 homolog B (UNC-45B).

IRS1_HUMAN
NC score	0.021827 (rank : 7)	θ value	3.0926 (rank : 9)
Query Neighborhood Hits	21	Target Neighborhood Hits	109	Shared Neighborhood Hits	2
SwissProt Accessions	P35568	Gene names	IRS1
Domain Architecture
Description	Insulin receptor substrate 1 (IRS-1).

NPAS4_MOUSE
NC score	0.017617 (rank : 8)	θ value	8.99809 (rank : 20)
Query Neighborhood Hits	21	Target Neighborhood Hits	245	Shared Neighborhood Hits	6
SwissProt Accessions	Q8BGD7, Q3V3U3	Gene names	Npas4, Nxf
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF) (Limbic-enhanced PAS protein) (LE-PAS).

TAF6L_HUMAN
NC score	0.017284 (rank : 9)	θ value	6.88961 (rank : 17)
Query Neighborhood Hits	21	Target Neighborhood Hits	30	Shared Neighborhood Hits	2
SwissProt Accessions	Q9Y6J9, Q96HA6	Gene names	TAF6L, PAF65A
Domain Architecture
Description	TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L (PCAF-associated factor 65 alpha) (PAF65- alpha).

NPAS4_HUMAN
NC score	0.016971 (rank : 10)	θ value	8.99809 (rank : 19)
Query Neighborhood Hits	21	Target Neighborhood Hits	214	Shared Neighborhood Hits	5
SwissProt Accessions	Q8IUM7, Q8N8S5, Q8N9Q9	Gene names	NPAS4, NXF
Domain Architecture	No domain graphic available
Description	Neuronal PAS domain-containing protein 4 (Neuronal PAS4) (HLH-PAS transcription factor NXF).

HNRPR_HUMAN
NC score	0.014267 (rank : 11)	θ value	3.0926 (rank : 8)
Query Neighborhood Hits	21	Target Neighborhood Hits	240	Shared Neighborhood Hits	2
SwissProt Accessions	O43390	Gene names	HNRPR
Domain Architecture
Description	Heterogeneous nuclear ribonucleoprotein R (hnRNP R).

B4GN4_HUMAN
NC score	0.013761 (rank : 12)	θ value	6.88961 (rank : 16)
Query Neighborhood Hits	21	Target Neighborhood Hits	131	Shared Neighborhood Hits	3
SwissProt Accessions	Q76KP1, Q96LV2	Gene names	B4GALNT4
Domain Architecture	No domain graphic available
Description	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N- acetylgalactosaminyltransferase 1 (EC 2.4.1.244) (NGalNAc-T1) (Beta- 1,4-N-acetylgalactosaminyltransferase IV) (Beta4GalNAc-T4) (Beta4GalNAcT4).

BSN_MOUSE
NC score	0.012242 (rank : 13)	θ value	4.03905 (rank : 10)
Query Neighborhood Hits	21	Target Neighborhood Hits	2057	Shared Neighborhood Hits	7
SwissProt Accessions	O88737, Q6ZQB5	Gene names	Bsn, Kiaa0434
Domain Architecture	No domain graphic available
Description	Protein bassoon.

PHX2A_MOUSE
NC score	0.010406 (rank : 14)	θ value	4.03905 (rank : 12)
Query Neighborhood Hits	21	Target Neighborhood Hits	338	Shared Neighborhood Hits	3
SwissProt Accessions	Q62066	Gene names	Phox2a, Arix, Phox2, Pmx2, Pmx2a
Domain Architecture
Description	Paired mesoderm homeobox protein 2A (Paired-like homeobox 2A) (PHOX2A homeodomain protein) (Aristaless homeobox protein homolog).

PHX2A_HUMAN
NC score	0.010205 (rank : 15)	θ value	4.03905 (rank : 11)
Query Neighborhood Hits	21	Target Neighborhood Hits	345	Shared Neighborhood Hits	3
SwissProt Accessions	O14813, Q8IVZ2	Gene names	PHOX2A, ARIX, PMX2A
Domain Architecture
Description	Paired mesoderm homeobox protein 2A (Paired-like homeobox 2A) (Aristaless homeobox protein homolog) (ARIX1 homeodomain protein).

SCAM3_MOUSE
NC score	0.010102 (rank : 16)	θ value	8.99809 (rank : 21)
Query Neighborhood Hits	21	Target Neighborhood Hits	28	Shared Neighborhood Hits	2
SwissProt Accessions	O35609, Q99M48, Q9ERM9	Gene names	Scamp3
Domain Architecture
Description	Secretory carrier-associated membrane protein 3 (Secretory carrier membrane protein 3).

MYO5B_HUMAN
NC score	0.009591 (rank : 17)	θ value	2.36792 (rank : 7)
Query Neighborhood Hits	21	Target Neighborhood Hits	911	Shared Neighborhood Hits	4
SwissProt Accessions	Q9ULV0	Gene names	MYO5B, KIAA1119
Domain Architecture
Description	Myosin-5B (Myosin Vb).

MYH14_HUMAN
NC score	0.008581 (rank : 18)	θ value	5.27518 (rank : 13)
Query Neighborhood Hits	21	Target Neighborhood Hits	995	Shared Neighborhood Hits	4
SwissProt Accessions	Q7Z406, Q5CZ75, Q6XYE4, Q76B62, Q8WV23, Q96I22, Q9BT27, Q9BW35, Q9H882	Gene names	MYH14, KIAA2034
Domain Architecture	No domain graphic available
Description	Myosin-14 (Myosin heavy chain, nonmuscle IIc) (Nonmuscle myosin heavy chain IIc) (NMHC II-C).

ETV3_HUMAN
NC score	0.007425 (rank : 19)	θ value	8.99809 (rank : 18)
Query Neighborhood Hits	21	Target Neighborhood Hits	312	Shared Neighborhood Hits	3
SwissProt Accessions	P41162, Q8TAC8, Q9BX30	Gene names	ETV3, METS, PE1
Domain Architecture	No domain graphic available
Description	ETS translocation variant 3 (ETS-domain transcriptional repressor PE1) (PE-1) (Mitogenic Ets transcriptional suppressor).

WNK4_HUMAN
NC score	0.003781 (rank : 20)	θ value	5.27518 (rank : 14)
Query Neighborhood Hits	21	Target Neighborhood Hits	1043	Shared Neighborhood Hits	6
SwissProt Accessions	Q96J92, Q8N8X3, Q8N8Z2, Q96DT8, Q9BYS5	Gene names	WNK4, PRKWNK4
Domain Architecture
Description	Serine/threonine-protein kinase WNK4 (EC 2.7.11.1) (Protein kinase with no lysine 4) (Protein kinase, lysine-deficient 4).

ACK1_HUMAN
NC score	0.001975 (rank : 21)	θ value	6.88961 (rank : 15)
Query Neighborhood Hits	21	Target Neighborhood Hits	1140	Shared Neighborhood Hits	5
SwissProt Accessions	Q07912, Q8N6U7, Q96H59	Gene names	TNK2, ACK1
Domain Architecture
Description	Activated CDC42 kinase 1 (EC 2.7.10.2) (ACK-1) (Tyrosine kinase non- receptor protein 2).