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Network neighborhood for query Sequence : DPOLA_MOUSE

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DPOLA_MOUSE
SwissProt Accessions	P33609	Gene names	Pola1, Pola
Domain Architecture
Description	DNA polymerase alpha catalytic subunit (EC 2.7.7.7).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

DPOLA_HUMAN
θ value	0 (rank : 1)	NC score	0.990766 (rank : 2)
Query Neighborhood Hits	56	Target Neighborhood Hits	41	Shared Neighborhood Hits	19
SwissProt Accessions	P09884, Q86UQ7	Gene names	POLA1, POLA
Domain Architecture
Description	DNA polymerase alpha catalytic subunit (EC 2.7.7.7).

DPOLA_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	56	Target Neighborhood Hits	56	Shared Neighborhood Hits	56
SwissProt Accessions	P33609	Gene names	Pola1, Pola
Domain Architecture
Description	DNA polymerase alpha catalytic subunit (EC 2.7.7.7).

DPOD1_MOUSE
θ value	3.60269e-49 (rank : 3)	NC score	0.758246 (rank : 3)
Query Neighborhood Hits	56	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	P52431, O54883	Gene names	Pold1
Domain Architecture
Description	DNA polymerase delta catalytic subunit (EC 2.7.7.7).

DPOD1_HUMAN
θ value	3.37202e-47 (rank : 4)	NC score	0.753661 (rank : 4)
Query Neighborhood Hits	56	Target Neighborhood Hits	28	Shared Neighborhood Hits	8
SwissProt Accessions	P28340, Q8NER3, Q96H98	Gene names	POLD1, POLD
Domain Architecture
Description	DNA polymerase delta catalytic subunit (EC 2.7.7.7) (DNA polymerase subunit delta p125).

DPOLZ_HUMAN
θ value	1.46948e-34 (rank : 5)	NC score	0.638419 (rank : 6)
Query Neighborhood Hits	56	Target Neighborhood Hits	200	Shared Neighborhood Hits	10
SwissProt Accessions	O60673, O43214	Gene names	REV3L, POLZ, REV3
Domain Architecture
Description	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (hREV3).

DPOLZ_MOUSE
θ value	1.6247e-33 (rank : 6)	NC score	0.639734 (rank : 5)
Query Neighborhood Hits	56	Target Neighborhood Hits	169	Shared Neighborhood Hits	11
SwissProt Accessions	Q61493, Q9JMD6, Q9QWX6	Gene names	Rev3l, Polz, Sez4
Domain Architecture
Description	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (Seizure-related protein 4).

DPOE1_HUMAN
θ value	3.19293e-05 (rank : 7)	NC score	0.209954 (rank : 7)
Query Neighborhood Hits	56	Target Neighborhood Hits	42	Shared Neighborhood Hits	7
SwissProt Accessions	Q07864, Q13533, Q86VH9	Gene names	POLE, POLE1
Domain Architecture
Description	DNA polymerase epsilon, catalytic subunit A (EC 2.7.7.7) (DNA polymerase II subunit A).

DPOE1_MOUSE
θ value	0.000270298 (rank : 8)	NC score	0.201230 (rank : 8)
Query Neighborhood Hits	56	Target Neighborhood Hits	24	Shared Neighborhood Hits	7
SwissProt Accessions	Q9WVF7, Q9QX50	Gene names	Pole, Pole1
Domain Architecture
Description	DNA polymerase epsilon, catalytic subunit A (EC 2.7.7.7) (DNA polymerase II subunit A).

PELP1_HUMAN
θ value	0.0330416 (rank : 9)	NC score	0.071048 (rank : 10)
Query Neighborhood Hits	56	Target Neighborhood Hits	596	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

PELP1_MOUSE
θ value	0.0431538 (rank : 10)	NC score	0.070306 (rank : 11)
Query Neighborhood Hits	56	Target Neighborhood Hits	709	Shared Neighborhood Hits	14
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

GPTC8_HUMAN
θ value	0.0736092 (rank : 11)	NC score	0.059848 (rank : 13)
Query Neighborhood Hits	56	Target Neighborhood Hits	366	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

SPAT2_HUMAN
θ value	0.163984 (rank : 12)	NC score	0.071602 (rank : 9)
Query Neighborhood Hits	56	Target Neighborhood Hits	39	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UM82, O94857	Gene names	SPATA2, KIAA0757, PD1
Domain Architecture	No domain graphic available
Description	Spermatogenesis-associated protein 2 (Spermatogenesis-associated protein PD1).

MYST4_HUMAN
θ value	0.279714 (rank : 13)	NC score	0.029203 (rank : 22)
Query Neighborhood Hits	56	Target Neighborhood Hits	671	Shared Neighborhood Hits	17
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

GNAS3_MOUSE
θ value	0.365318 (rank : 14)	NC score	0.064287 (rank : 12)
Query Neighborhood Hits	56	Target Neighborhood Hits	84	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z0F1, Q9QXW5, Q9Z0H2	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Neuroendocrine secretory protein 55 (NESP55) [Contains: LHAL tetrapeptide; GPIPIRRH peptide].

SMRC2_HUMAN
θ value	0.47712 (rank : 15)	NC score	0.028028 (rank : 24)
Query Neighborhood Hits	56	Target Neighborhood Hits	499	Shared Neighborhood Hits	15
SwissProt Accessions	Q8TAQ2, Q92923, Q96E12, Q96GY4	Gene names	SMARCC2, BAF170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

BMP2K_MOUSE
θ value	0.62314 (rank : 16)	NC score	0.010057 (rank : 45)
Query Neighborhood Hits	56	Target Neighborhood Hits	874	Shared Neighborhood Hits	9
SwissProt Accessions	Q91Z96, Q8C8L7	Gene names	Bmp2k, Bike
Domain Architecture
Description	BMP-2-inducible protein kinase (EC 2.7.11.1) (BIKe).

CDN1C_MOUSE
θ value	0.813845 (rank : 17)	NC score	0.039149 (rank : 16)
Query Neighborhood Hits	56	Target Neighborhood Hits	161	Shared Neighborhood Hits	8
SwissProt Accessions	P49919	Gene names	Cdkn1c, Kip2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

IWS1_MOUSE
θ value	1.06291 (rank : 18)	NC score	0.029072 (rank : 23)
Query Neighborhood Hits	56	Target Neighborhood Hits	1258	Shared Neighborhood Hits	28
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

TNIK_HUMAN
θ value	1.06291 (rank : 19)	NC score	0.006224 (rank : 51)
Query Neighborhood Hits	56	Target Neighborhood Hits	1570	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UKE5, O60298, Q8WUY7, Q9UKD8, Q9UKD9, Q9UKE0, Q9UKE1, Q9UKE2, Q9UKE3, Q9UKE4	Gene names	TNIK, KIAA0551
Domain Architecture
Description	TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1).

DHX8_HUMAN
θ value	1.38821 (rank : 20)	NC score	0.012673 (rank : 43)
Query Neighborhood Hits	56	Target Neighborhood Hits	86	Shared Neighborhood Hits	2
SwissProt Accessions	Q14562	Gene names	DHX8, DDX8
Domain Architecture
Description	ATP-dependent RNA helicase DHX8 (EC 3.6.1.-) (DEAH box protein 8) (RNA helicase HRH1).

RAIN_HUMAN
θ value	1.38821 (rank : 21)	NC score	0.040820 (rank : 15)
Query Neighborhood Hits	56	Target Neighborhood Hits	33	Shared Neighborhood Hits	4
SwissProt Accessions	Q5U651, Q6U676	Gene names	RASIP1
Domain Architecture	No domain graphic available
Description	Ras-interacting protein 1 (Rain).

RPGR1_MOUSE
θ value	1.38821 (rank : 22)	NC score	0.023122 (rank : 28)
Query Neighborhood Hits	56	Target Neighborhood Hits	713	Shared Neighborhood Hits	12
SwissProt Accessions	Q9EPQ2, Q8CAC2, Q8CDJ9, Q91WE0, Q9CUK6, Q9D5Q1	Gene names	Rpgrip1
Domain Architecture	No domain graphic available
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

AFF1_MOUSE
θ value	1.81305 (rank : 23)	NC score	0.029211 (rank : 21)
Query Neighborhood Hits	56	Target Neighborhood Hits	351	Shared Neighborhood Hits	11
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

ELF2_MOUSE
θ value	1.81305 (rank : 24)	NC score	0.030995 (rank : 18)
Query Neighborhood Hits	56	Target Neighborhood Hits	81	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JHC9, Q6NST2, Q8BTX8, Q9JHC7, Q9JHC8, Q9JHD0	Gene names	Elf2, Nerf
Domain Architecture	No domain graphic available
Description	ETS-related transcription factor Elf-2 (E74-like factor 2) (New ETS- related factor).

PPAC_HUMAN
θ value	1.81305 (rank : 25)	NC score	0.050948 (rank : 14)
Query Neighborhood Hits	56	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	P24666, P24667, Q16035, Q16036, Q16725	Gene names	ACP1
Domain Architecture
Description	Low molecular weight phosphotyrosine protein phosphatase (EC 3.1.3.48) (LMW-PTP) (Low molecular weight cytosolic acid phosphatase) (EC 3.1.3.2) (Red cell acid phosphatase 1) (PTPase) (Adipocyte acid phosphatase).

AKAP8_MOUSE
θ value	2.36792 (rank : 26)	NC score	0.030783 (rank : 19)
Query Neighborhood Hits	56	Target Neighborhood Hits	76	Shared Neighborhood Hits	3
SwissProt Accessions	Q9DBR0, Q9R0L8	Gene names	Akap8, Akap95
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 8 (A-kinase anchor protein 95 kDa) (AKAP 95).

MAST2_MOUSE
θ value	2.36792 (rank : 27)	NC score	0.003046 (rank : 55)
Query Neighborhood Hits	56	Target Neighborhood Hits	1110	Shared Neighborhood Hits	8
SwissProt Accessions	Q60592, Q6P9M1, Q8CHD1	Gene names	Mast2, Mast205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

TAF3_MOUSE
θ value	2.36792 (rank : 28)	NC score	0.027982 (rank : 25)
Query Neighborhood Hits	56	Target Neighborhood Hits	463	Shared Neighborhood Hits	12
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

TITIN_HUMAN
θ value	2.36792 (rank : 29)	NC score	0.005263 (rank : 52)
Query Neighborhood Hits	56	Target Neighborhood Hits	2923	Shared Neighborhood Hits	22
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

TTF2_HUMAN
θ value	2.36792 (rank : 30)	NC score	0.016168 (rank : 36)
Query Neighborhood Hits	56	Target Neighborhood Hits	98	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UNY4, O75921, Q5T2K7, Q5VVU8, Q8N6I8	Gene names	TTF2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2) (Factor 2) (F2) (HuF2) (Lodestar homolog).

G3BP2_MOUSE
θ value	3.0926 (rank : 31)	NC score	0.016789 (rank : 35)
Query Neighborhood Hits	56	Target Neighborhood Hits	258	Shared Neighborhood Hits	7
SwissProt Accessions	P97379, Q9R1B8	Gene names	G3bp2
Domain Architecture
Description	Ras-GTPase-activating protein-binding protein 2 (GAP SH3-domain- binding protein 2) (G3BP-2).

IF2P_HUMAN
θ value	3.0926 (rank : 32)	NC score	0.013827 (rank : 41)
Query Neighborhood Hits	56	Target Neighborhood Hits	889	Shared Neighborhood Hits	12
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

NU160_HUMAN
θ value	3.0926 (rank : 33)	NC score	0.030592 (rank : 20)
Query Neighborhood Hits	56	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	Q12769, Q96GB3, Q9H660	Gene names	NUP160, KIAA0197, NUP120
Domain Architecture	No domain graphic available
Description	Nuclear pore complex protein Nup160 (Nucleoporin Nup160) (160 kDa nucleoporin).

NU160_MOUSE
θ value	3.0926 (rank : 34)	NC score	0.035837 (rank : 17)
Query Neighborhood Hits	56	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z0W3, Q3TBI7, Q3TP11, Q3U250, Q6A0A7, Q7TME1, Q9CZD9	Gene names	Nup160, Gtl1-13, Kiaa0197
Domain Architecture	No domain graphic available
Description	Nuclear pore complex protein Nup160 (Nucleoporin Nup160) (160 kDa nucleoporin) (Gene trap locus 1-13) (GTL-13).

ST1C1_MOUSE
θ value	3.0926 (rank : 35)	NC score	0.009608 (rank : 47)
Query Neighborhood Hits	56	Target Neighborhood Hits	35	Shared Neighborhood Hits	2
SwissProt Accessions	Q80VR3, O70262	Gene names	Sult1c1, Sult1a2
Domain Architecture	No domain graphic available
Description	Sulfotransferase 1C1 (EC 2.8.2.-) (Phenol sulfotransferase).

T240L_HUMAN
θ value	3.0926 (rank : 36)	NC score	0.016919 (rank : 34)
Query Neighborhood Hits	56	Target Neighborhood Hits	132	Shared Neighborhood Hits	4
SwissProt Accessions	Q71F56, Q68DN4, Q9H8C0, Q9NSY9, Q9UFD8, Q9UPX5	Gene names	THRAP2, KIAA1025, PROSIT240, TRAP240L
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 2 (Thyroid hormone receptor-associated protein complex 240 kDa component-like).

IF4G3_HUMAN
θ value	4.03905 (rank : 37)	NC score	0.013951 (rank : 40)
Query Neighborhood Hits	56	Target Neighborhood Hits	247	Shared Neighborhood Hits	10
SwissProt Accessions	O43432, Q15597, Q8NEN1	Gene names	EIF4G3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

K1849_MOUSE
θ value	4.03905 (rank : 38)	NC score	0.017215 (rank : 33)
Query Neighborhood Hits	56	Target Neighborhood Hits	335	Shared Neighborhood Hits	7
SwissProt Accessions	Q69Z89, Q8BNL0, Q8C549, Q8CAL1	Gene names	Kiaa1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

NUF2_MOUSE
θ value	4.03905 (rank : 39)	NC score	0.019811 (rank : 32)
Query Neighborhood Hits	56	Target Neighborhood Hits	585	Shared Neighborhood Hits	4
SwissProt Accessions	Q99P69, Q8BTK7, Q8VE05, Q9CST5	Gene names	Cdca1, Nuf2r
Domain Architecture	No domain graphic available
Description	Kinetochore protein Nuf2 (Cell division cycle-associated protein 1).

TNR6_MOUSE
θ value	4.03905 (rank : 40)	NC score	0.015205 (rank : 37)
Query Neighborhood Hits	56	Target Neighborhood Hits	99	Shared Neighborhood Hits	2
SwissProt Accessions	P25446, Q9DCQ1	Gene names	Fas, Apt1, Tnfrsf6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

YTHD3_HUMAN
θ value	4.03905 (rank : 41)	NC score	0.020665 (rank : 30)
Query Neighborhood Hits	56	Target Neighborhood Hits	63	Shared Neighborhood Hits	5
SwissProt Accessions	Q7Z739, Q63Z37, Q659A3	Gene names	YTHDF3
Domain Architecture	No domain graphic available
Description	YTH domain family protein 3.

YTHD3_MOUSE
θ value	4.03905 (rank : 42)	NC score	0.020660 (rank : 31)
Query Neighborhood Hits	56	Target Neighborhood Hits	63	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BYK6, Q3UVI5, Q6NXJ6, Q6NXJ8, Q8BKB6	Gene names	Ythdf3
Domain Architecture	No domain graphic available
Description	YTH domain family protein 3.

HCN2_MOUSE
θ value	5.27518 (rank : 43)	NC score	0.006712 (rank : 50)
Query Neighborhood Hits	56	Target Neighborhood Hits	278	Shared Neighborhood Hits	4
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

NACAM_MOUSE
θ value	5.27518 (rank : 44)	NC score	0.013500 (rank : 42)
Query Neighborhood Hits	56	Target Neighborhood Hits	1866	Shared Neighborhood Hits	26
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

WNK2_HUMAN
θ value	5.27518 (rank : 45)	NC score	0.003214 (rank : 54)
Query Neighborhood Hits	56	Target Neighborhood Hits	1407	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

ELF2_HUMAN
θ value	6.88961 (rank : 46)	NC score	0.023064 (rank : 29)
Query Neighborhood Hits	56	Target Neighborhood Hits	78	Shared Neighborhood Hits	5
SwissProt Accessions	Q15723, Q15724, Q15725, Q6P1K5	Gene names	ELF2, NERF
Domain Architecture	No domain graphic available
Description	ETS-related transcription factor Elf-2 (E74-like factor 2) (New ETS- related factor).

MYT1L_MOUSE
θ value	6.88961 (rank : 47)	NC score	0.011321 (rank : 44)
Query Neighborhood Hits	56	Target Neighborhood Hits	461	Shared Neighborhood Hits	7
SwissProt Accessions	P97500, O08996, Q8C643, Q8C7L4, Q8CHB4	Gene names	Myt1l, Kiaa1106, Nzf1, Png1
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1-like protein (MyT1L protein) (Postmitotic neural gene 1 protein) (Zinc finger protein Png-1) (Neural zinc finger factor 1) (NZF-1).

NSBP1_MOUSE
θ value	6.88961 (rank : 48)	NC score	0.023258 (rank : 27)
Query Neighborhood Hits	56	Target Neighborhood Hits	681	Shared Neighborhood Hits	16
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

SMUF2_HUMAN
θ value	6.88961 (rank : 49)	NC score	0.004764 (rank : 53)
Query Neighborhood Hits	56	Target Neighborhood Hits	142	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HAU4, Q9H260	Gene names	SMURF2
Domain Architecture
Description	Smad ubiquitination regulatory factor 2 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF2) (Smad-specific E3 ubiquitin ligase 2) (hSMURF2).

ADDB_MOUSE
θ value	8.99809 (rank : 50)	NC score	0.014669 (rank : 39)
Query Neighborhood Hits	56	Target Neighborhood Hits	574	Shared Neighborhood Hits	18
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

CC47_MOUSE
θ value	8.99809 (rank : 51)	NC score	0.024818 (rank : 26)
Query Neighborhood Hits	56	Target Neighborhood Hits	245	Shared Neighborhood Hits	15
SwissProt Accessions	Q9D024, Q3TSB5, Q3V1S7, Q8C5D9, Q920S6	Gene names	Ccdc47, Asp4
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 47 precursor (Adipocyte-specific protein 4).

E41L2_MOUSE
θ value	8.99809 (rank : 52)	NC score	0.008466 (rank : 48)
Query Neighborhood Hits	56	Target Neighborhood Hits	459	Shared Neighborhood Hits	17
SwissProt Accessions	O70318	Gene names	Epb41l2, Epb4.1l2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

MAP1B_HUMAN
θ value	8.99809 (rank : 53)	NC score	0.009713 (rank : 46)
Query Neighborhood Hits	56	Target Neighborhood Hits	903	Shared Neighborhood Hits	15
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

MYT1_MOUSE
θ value	8.99809 (rank : 54)	NC score	0.015042 (rank : 38)
Query Neighborhood Hits	56	Target Neighborhood Hits	385	Shared Neighborhood Hits	12
SwissProt Accessions	Q8CFC2, O08995, Q8CFH1	Gene names	Myt1, Kiaa0835, Nzf2
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1 (MyT1) (Neural zinc finger factor 2) (NZF-2).

NUCL_MOUSE
θ value	8.99809 (rank : 55)	NC score	0.008169 (rank : 49)
Query Neighborhood Hits	56	Target Neighborhood Hits	425	Shared Neighborhood Hits	13
SwissProt Accessions	P09405, Q548M9, Q61991, Q99K50	Gene names	Ncl, Nuc
Domain Architecture
Description	Nucleolin (Protein C23).

SPTB2_MOUSE
θ value	8.99809 (rank : 56)	NC score	0.002167 (rank : 56)
Query Neighborhood Hits	56	Target Neighborhood Hits	770	Shared Neighborhood Hits	8
SwissProt Accessions	Q62261, Q5SQL8	Gene names	Sptbn1, Spnb-2, Spnb2, Sptb2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).

Hits sorted by NC score

DPOLA_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	56	Target Neighborhood Hits	56	Shared Neighborhood Hits	56
SwissProt Accessions	P33609	Gene names	Pola1, Pola
Domain Architecture
Description	DNA polymerase alpha catalytic subunit (EC 2.7.7.7).

DPOLA_HUMAN
NC score	0.990766 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	56	Target Neighborhood Hits	41	Shared Neighborhood Hits	19
SwissProt Accessions	P09884, Q86UQ7	Gene names	POLA1, POLA
Domain Architecture
Description	DNA polymerase alpha catalytic subunit (EC 2.7.7.7).

DPOD1_MOUSE
NC score	0.758246 (rank : 3)	θ value	3.60269e-49 (rank : 3)
Query Neighborhood Hits	56	Target Neighborhood Hits	19	Shared Neighborhood Hits	8
SwissProt Accessions	P52431, O54883	Gene names	Pold1
Domain Architecture
Description	DNA polymerase delta catalytic subunit (EC 2.7.7.7).

DPOD1_HUMAN
NC score	0.753661 (rank : 4)	θ value	3.37202e-47 (rank : 4)
Query Neighborhood Hits	56	Target Neighborhood Hits	28	Shared Neighborhood Hits	8
SwissProt Accessions	P28340, Q8NER3, Q96H98	Gene names	POLD1, POLD
Domain Architecture
Description	DNA polymerase delta catalytic subunit (EC 2.7.7.7) (DNA polymerase subunit delta p125).

DPOLZ_MOUSE
NC score	0.639734 (rank : 5)	θ value	1.6247e-33 (rank : 6)
Query Neighborhood Hits	56	Target Neighborhood Hits	169	Shared Neighborhood Hits	11
SwissProt Accessions	Q61493, Q9JMD6, Q9QWX6	Gene names	Rev3l, Polz, Sez4
Domain Architecture
Description	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (Seizure-related protein 4).

DPOLZ_HUMAN
NC score	0.638419 (rank : 6)	θ value	1.46948e-34 (rank : 5)
Query Neighborhood Hits	56	Target Neighborhood Hits	200	Shared Neighborhood Hits	10
SwissProt Accessions	O60673, O43214	Gene names	REV3L, POLZ, REV3
Domain Architecture
Description	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (hREV3).

DPOE1_HUMAN
NC score	0.209954 (rank : 7)	θ value	3.19293e-05 (rank : 7)
Query Neighborhood Hits	56	Target Neighborhood Hits	42	Shared Neighborhood Hits	7
SwissProt Accessions	Q07864, Q13533, Q86VH9	Gene names	POLE, POLE1
Domain Architecture
Description	DNA polymerase epsilon, catalytic subunit A (EC 2.7.7.7) (DNA polymerase II subunit A).

DPOE1_MOUSE
NC score	0.201230 (rank : 8)	θ value	0.000270298 (rank : 8)
Query Neighborhood Hits	56	Target Neighborhood Hits	24	Shared Neighborhood Hits	7
SwissProt Accessions	Q9WVF7, Q9QX50	Gene names	Pole, Pole1
Domain Architecture
Description	DNA polymerase epsilon, catalytic subunit A (EC 2.7.7.7) (DNA polymerase II subunit A).

SPAT2_HUMAN
NC score	0.071602 (rank : 9)	θ value	0.163984 (rank : 12)
Query Neighborhood Hits	56	Target Neighborhood Hits	39	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UM82, O94857	Gene names	SPATA2, KIAA0757, PD1
Domain Architecture	No domain graphic available
Description	Spermatogenesis-associated protein 2 (Spermatogenesis-associated protein PD1).

PELP1_HUMAN
NC score	0.071048 (rank : 10)	θ value	0.0330416 (rank : 9)
Query Neighborhood Hits	56	Target Neighborhood Hits	596	Shared Neighborhood Hits	11
SwissProt Accessions	Q8IZL8, O15450, Q5EGN3, Q6NTE6, Q96FT1, Q9BU60	Gene names	PELP1, HMX3, MNAR
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor) (Transcription factor HMX3).

PELP1_MOUSE
NC score	0.070306 (rank : 11)	θ value	0.0431538 (rank : 10)
Query Neighborhood Hits	56	Target Neighborhood Hits	709	Shared Neighborhood Hits	14
SwissProt Accessions	Q9DBD5, Q5F2E2, Q6PEM0, Q91YM9	Gene names	Pelp1, Mnar
Domain Architecture	No domain graphic available
Description	Proline-, glutamic acid- and leucine-rich protein 1 (Modulator of nongenomic activity of estrogen receptor).

GNAS3_MOUSE
NC score	0.064287 (rank : 12)	θ value	0.365318 (rank : 14)
Query Neighborhood Hits	56	Target Neighborhood Hits	84	Shared Neighborhood Hits	5
SwissProt Accessions	Q9Z0F1, Q9QXW5, Q9Z0H2	Gene names	Gnas, Gnas1
Domain Architecture	No domain graphic available
Description	Neuroendocrine secretory protein 55 (NESP55) [Contains: LHAL tetrapeptide; GPIPIRRH peptide].

GPTC8_HUMAN
NC score	0.059848 (rank : 13)	θ value	0.0736092 (rank : 11)
Query Neighborhood Hits	56	Target Neighborhood Hits	366	Shared Neighborhood Hits	8
SwissProt Accessions	Q9UKJ3, O60300	Gene names	GPATC8, KIAA0553
Domain Architecture	No domain graphic available
Description	G patch domain-containing protein 8.

PPAC_HUMAN
NC score	0.050948 (rank : 14)	θ value	1.81305 (rank : 25)
Query Neighborhood Hits	56	Target Neighborhood Hits	7	Shared Neighborhood Hits	3
SwissProt Accessions	P24666, P24667, Q16035, Q16036, Q16725	Gene names	ACP1
Domain Architecture
Description	Low molecular weight phosphotyrosine protein phosphatase (EC 3.1.3.48) (LMW-PTP) (Low molecular weight cytosolic acid phosphatase) (EC 3.1.3.2) (Red cell acid phosphatase 1) (PTPase) (Adipocyte acid phosphatase).

RAIN_HUMAN
NC score	0.040820 (rank : 15)	θ value	1.38821 (rank : 21)
Query Neighborhood Hits	56	Target Neighborhood Hits	33	Shared Neighborhood Hits	4
SwissProt Accessions	Q5U651, Q6U676	Gene names	RASIP1
Domain Architecture	No domain graphic available
Description	Ras-interacting protein 1 (Rain).

CDN1C_MOUSE
NC score	0.039149 (rank : 16)	θ value	0.813845 (rank : 17)
Query Neighborhood Hits	56	Target Neighborhood Hits	161	Shared Neighborhood Hits	8
SwissProt Accessions	P49919	Gene names	Cdkn1c, Kip2
Domain Architecture
Description	Cyclin-dependent kinase inhibitor 1C (Cyclin-dependent kinase inhibitor p57) (p57KIP2).

NU160_MOUSE
NC score	0.035837 (rank : 17)	θ value	3.0926 (rank : 34)
Query Neighborhood Hits	56	Target Neighborhood Hits	19	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z0W3, Q3TBI7, Q3TP11, Q3U250, Q6A0A7, Q7TME1, Q9CZD9	Gene names	Nup160, Gtl1-13, Kiaa0197
Domain Architecture	No domain graphic available
Description	Nuclear pore complex protein Nup160 (Nucleoporin Nup160) (160 kDa nucleoporin) (Gene trap locus 1-13) (GTL-13).

ELF2_MOUSE
NC score	0.030995 (rank : 18)	θ value	1.81305 (rank : 24)
Query Neighborhood Hits	56	Target Neighborhood Hits	81	Shared Neighborhood Hits	5
SwissProt Accessions	Q9JHC9, Q6NST2, Q8BTX8, Q9JHC7, Q9JHC8, Q9JHD0	Gene names	Elf2, Nerf
Domain Architecture	No domain graphic available
Description	ETS-related transcription factor Elf-2 (E74-like factor 2) (New ETS- related factor).

AKAP8_MOUSE
NC score	0.030783 (rank : 19)	θ value	2.36792 (rank : 26)
Query Neighborhood Hits	56	Target Neighborhood Hits	76	Shared Neighborhood Hits	3
SwissProt Accessions	Q9DBR0, Q9R0L8	Gene names	Akap8, Akap95
Domain Architecture	No domain graphic available
Description	A-kinase anchor protein 8 (A-kinase anchor protein 95 kDa) (AKAP 95).

NU160_HUMAN
NC score	0.030592 (rank : 20)	θ value	3.0926 (rank : 33)
Query Neighborhood Hits	56	Target Neighborhood Hits	16	Shared Neighborhood Hits	3
SwissProt Accessions	Q12769, Q96GB3, Q9H660	Gene names	NUP160, KIAA0197, NUP120
Domain Architecture	No domain graphic available
Description	Nuclear pore complex protein Nup160 (Nucleoporin Nup160) (160 kDa nucleoporin).

AFF1_MOUSE
NC score	0.029211 (rank : 21)	θ value	1.81305 (rank : 23)
Query Neighborhood Hits	56	Target Neighborhood Hits	351	Shared Neighborhood Hits	11
SwissProt Accessions	O88573	Gene names	Aff1, Mllt2, Mllt2h
Domain Architecture
Description	AF4/FMR2 family member 1 (Protein AF-4) (Proto-oncogene AF4).

MYST4_HUMAN
NC score	0.029203 (rank : 22)	θ value	0.279714 (rank : 13)
Query Neighborhood Hits	56	Target Neighborhood Hits	671	Shared Neighborhood Hits	17
SwissProt Accessions	Q8WYB5, O15087, Q86Y05, Q8WU81, Q9UKW2, Q9UKW3, Q9UKX0	Gene names	MYST4, KIAA0383, MORF, MOZ2
Domain Architecture	No domain graphic available
Description	Histone acetyltransferase MYST4 (EC 2.3.1.48) (EC 2.3.1.-) (MYST protein 4) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (Histone acetyltransferase MOZ2) (Monocytic leukemia zinc finger protein- related factor) (Histone acetyltransferase MORF).

IWS1_MOUSE
NC score	0.029072 (rank : 23)	θ value	1.06291 (rank : 18)
Query Neighborhood Hits	56	Target Neighborhood Hits	1258	Shared Neighborhood Hits	28
SwissProt Accessions	Q8C1D8, Q3TQ25, Q3UWB0, Q6NVD1, Q8BY73, Q9D9H4	Gene names	Iws1, Iws1l
Domain Architecture	No domain graphic available
Description	IWS1 homolog (IWS1-like protein).

SMRC2_HUMAN
NC score	0.028028 (rank : 24)	θ value	0.47712 (rank : 15)
Query Neighborhood Hits	56	Target Neighborhood Hits	499	Shared Neighborhood Hits	15
SwissProt Accessions	Q8TAQ2, Q92923, Q96E12, Q96GY4	Gene names	SMARCC2, BAF170
Domain Architecture	No domain graphic available
Description	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2 (SWI/SNF complex 170 kDa subunit) (BRG1-associated factor 170).

TAF3_MOUSE
NC score	0.027982 (rank : 25)	θ value	2.36792 (rank : 28)
Query Neighborhood Hits	56	Target Neighborhood Hits	463	Shared Neighborhood Hits	12
SwissProt Accessions	Q5HZG4, Q3U490, Q3UWX2, Q8BIU8, Q99JH4	Gene names	Taf3
Domain Architecture	No domain graphic available
Description	Transcription initiation factor TFIID subunit 3 (TBP-associated factor 3) (Transcription initiation factor TFIID 140 kDa subunit) (140 kDa TATA box-binding protein-associated factor) (TAF140) (TAFII140).

CC47_MOUSE
NC score	0.024818 (rank : 26)	θ value	8.99809 (rank : 51)
Query Neighborhood Hits	56	Target Neighborhood Hits	245	Shared Neighborhood Hits	15
SwissProt Accessions	Q9D024, Q3TSB5, Q3V1S7, Q8C5D9, Q920S6	Gene names	Ccdc47, Asp4
Domain Architecture	No domain graphic available
Description	Coiled-coil domain-containing protein 47 precursor (Adipocyte-specific protein 4).

NSBP1_MOUSE
NC score	0.023258 (rank : 27)	θ value	6.88961 (rank : 48)
Query Neighborhood Hits	56	Target Neighborhood Hits	681	Shared Neighborhood Hits	16
SwissProt Accessions	Q9JL35, O88832, Q8VC71, Q9CUW1	Gene names	Nsbp1, Garp45
Domain Architecture	No domain graphic available
Description	Nucleosome-binding protein 1 (Nucleosome-binding protein 45) (NBP-45) (GARP45 protein).

RPGR1_MOUSE
NC score	0.023122 (rank : 28)	θ value	1.38821 (rank : 22)
Query Neighborhood Hits	56	Target Neighborhood Hits	713	Shared Neighborhood Hits	12
SwissProt Accessions	Q9EPQ2, Q8CAC2, Q8CDJ9, Q91WE0, Q9CUK6, Q9D5Q1	Gene names	Rpgrip1
Domain Architecture	No domain graphic available
Description	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (RPGR-interacting protein 1).

ELF2_HUMAN
NC score	0.023064 (rank : 29)	θ value	6.88961 (rank : 46)
Query Neighborhood Hits	56	Target Neighborhood Hits	78	Shared Neighborhood Hits	5
SwissProt Accessions	Q15723, Q15724, Q15725, Q6P1K5	Gene names	ELF2, NERF
Domain Architecture	No domain graphic available
Description	ETS-related transcription factor Elf-2 (E74-like factor 2) (New ETS- related factor).

YTHD3_HUMAN
NC score	0.020665 (rank : 30)	θ value	4.03905 (rank : 41)
Query Neighborhood Hits	56	Target Neighborhood Hits	63	Shared Neighborhood Hits	5
SwissProt Accessions	Q7Z739, Q63Z37, Q659A3	Gene names	YTHDF3
Domain Architecture	No domain graphic available
Description	YTH domain family protein 3.

YTHD3_MOUSE
NC score	0.020660 (rank : 31)	θ value	4.03905 (rank : 42)
Query Neighborhood Hits	56	Target Neighborhood Hits	63	Shared Neighborhood Hits	5
SwissProt Accessions	Q8BYK6, Q3UVI5, Q6NXJ6, Q6NXJ8, Q8BKB6	Gene names	Ythdf3
Domain Architecture	No domain graphic available
Description	YTH domain family protein 3.

NUF2_MOUSE
NC score	0.019811 (rank : 32)	θ value	4.03905 (rank : 39)
Query Neighborhood Hits	56	Target Neighborhood Hits	585	Shared Neighborhood Hits	4
SwissProt Accessions	Q99P69, Q8BTK7, Q8VE05, Q9CST5	Gene names	Cdca1, Nuf2r
Domain Architecture	No domain graphic available
Description	Kinetochore protein Nuf2 (Cell division cycle-associated protein 1).

K1849_MOUSE
NC score	0.017215 (rank : 33)	θ value	4.03905 (rank : 38)
Query Neighborhood Hits	56	Target Neighborhood Hits	335	Shared Neighborhood Hits	7
SwissProt Accessions	Q69Z89, Q8BNL0, Q8C549, Q8CAL1	Gene names	Kiaa1849
Domain Architecture	No domain graphic available
Description	Protein KIAA1849.

T240L_HUMAN
NC score	0.016919 (rank : 34)	θ value	3.0926 (rank : 36)
Query Neighborhood Hits	56	Target Neighborhood Hits	132	Shared Neighborhood Hits	4
SwissProt Accessions	Q71F56, Q68DN4, Q9H8C0, Q9NSY9, Q9UFD8, Q9UPX5	Gene names	THRAP2, KIAA1025, PROSIT240, TRAP240L
Domain Architecture	No domain graphic available
Description	Thyroid hormone receptor-associated protein 2 (Thyroid hormone receptor-associated protein complex 240 kDa component-like).

G3BP2_MOUSE
NC score	0.016789 (rank : 35)	θ value	3.0926 (rank : 31)
Query Neighborhood Hits	56	Target Neighborhood Hits	258	Shared Neighborhood Hits	7
SwissProt Accessions	P97379, Q9R1B8	Gene names	G3bp2
Domain Architecture
Description	Ras-GTPase-activating protein-binding protein 2 (GAP SH3-domain- binding protein 2) (G3BP-2).

TTF2_HUMAN
NC score	0.016168 (rank : 36)	θ value	2.36792 (rank : 30)
Query Neighborhood Hits	56	Target Neighborhood Hits	98	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UNY4, O75921, Q5T2K7, Q5VVU8, Q8N6I8	Gene names	TTF2
Domain Architecture	No domain graphic available
Description	Transcription termination factor 2 (EC 3.6.1.-) (RNA polymerase II termination factor) (Transcription release factor 2) (Factor 2) (F2) (HuF2) (Lodestar homolog).

TNR6_MOUSE
NC score	0.015205 (rank : 37)	θ value	4.03905 (rank : 40)
Query Neighborhood Hits	56	Target Neighborhood Hits	99	Shared Neighborhood Hits	2
SwissProt Accessions	P25446, Q9DCQ1	Gene names	Fas, Apt1, Tnfrsf6
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 6 precursor (FASLG receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen).

MYT1_MOUSE
NC score	0.015042 (rank : 38)	θ value	8.99809 (rank : 54)
Query Neighborhood Hits	56	Target Neighborhood Hits	385	Shared Neighborhood Hits	12
SwissProt Accessions	Q8CFC2, O08995, Q8CFH1	Gene names	Myt1, Kiaa0835, Nzf2
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1 (MyT1) (Neural zinc finger factor 2) (NZF-2).

ADDB_MOUSE
NC score	0.014669 (rank : 39)	θ value	8.99809 (rank : 50)
Query Neighborhood Hits	56	Target Neighborhood Hits	574	Shared Neighborhood Hits	18
SwissProt Accessions	Q9QYB8, Q3U0E1, Q80VH9, Q8C1C4, Q9CXE3, Q9JLE5, Q9QYB7	Gene names	Add2
Domain Architecture
Description	Beta-adducin (Erythrocyte adducin subunit beta) (Add97).

IF4G3_HUMAN
NC score	0.013951 (rank : 40)	θ value	4.03905 (rank : 37)
Query Neighborhood Hits	56	Target Neighborhood Hits	247	Shared Neighborhood Hits	10
SwissProt Accessions	O43432, Q15597, Q8NEN1	Gene names	EIF4G3
Domain Architecture
Description	Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII).

IF2P_HUMAN
NC score	0.013827 (rank : 41)	θ value	3.0926 (rank : 32)
Query Neighborhood Hits	56	Target Neighborhood Hits	889	Shared Neighborhood Hits	12
SwissProt Accessions	O60841, O95805, Q9UF81, Q9UMN7	Gene names	EIF5B, IF2, KIAA0741
Domain Architecture
Description	Eukaryotic translation initiation factor 5B (eIF-5B) (Translation initiation factor IF-2).

NACAM_MOUSE
NC score	0.013500 (rank : 42)	θ value	5.27518 (rank : 44)
Query Neighborhood Hits	56	Target Neighborhood Hits	1866	Shared Neighborhood Hits	26
SwissProt Accessions	P70670	Gene names	Naca
Domain Architecture	No domain graphic available
Description	Nascent polypeptide-associated complex subunit alpha, muscle-specific form (Alpha-NAC, muscle-specific form).

DHX8_HUMAN
NC score	0.012673 (rank : 43)	θ value	1.38821 (rank : 20)
Query Neighborhood Hits	56	Target Neighborhood Hits	86	Shared Neighborhood Hits	2
SwissProt Accessions	Q14562	Gene names	DHX8, DDX8
Domain Architecture
Description	ATP-dependent RNA helicase DHX8 (EC 3.6.1.-) (DEAH box protein 8) (RNA helicase HRH1).

MYT1L_MOUSE
NC score	0.011321 (rank : 44)	θ value	6.88961 (rank : 47)
Query Neighborhood Hits	56	Target Neighborhood Hits	461	Shared Neighborhood Hits	7
SwissProt Accessions	P97500, O08996, Q8C643, Q8C7L4, Q8CHB4	Gene names	Myt1l, Kiaa1106, Nzf1, Png1
Domain Architecture	No domain graphic available
Description	Myelin transcription factor 1-like protein (MyT1L protein) (Postmitotic neural gene 1 protein) (Zinc finger protein Png-1) (Neural zinc finger factor 1) (NZF-1).

BMP2K_MOUSE
NC score	0.010057 (rank : 45)	θ value	0.62314 (rank : 16)
Query Neighborhood Hits	56	Target Neighborhood Hits	874	Shared Neighborhood Hits	9
SwissProt Accessions	Q91Z96, Q8C8L7	Gene names	Bmp2k, Bike
Domain Architecture
Description	BMP-2-inducible protein kinase (EC 2.7.11.1) (BIKe).

MAP1B_HUMAN
NC score	0.009713 (rank : 46)	θ value	8.99809 (rank : 53)
Query Neighborhood Hits	56	Target Neighborhood Hits	903	Shared Neighborhood Hits	15
SwissProt Accessions	P46821	Gene names	MAP1B
Domain Architecture	No domain graphic available
Description	Microtubule-associated protein 1B (MAP 1B) [Contains: MAP1 light chain LC1].

ST1C1_MOUSE
NC score	0.009608 (rank : 47)	θ value	3.0926 (rank : 35)
Query Neighborhood Hits	56	Target Neighborhood Hits	35	Shared Neighborhood Hits	2
SwissProt Accessions	Q80VR3, O70262	Gene names	Sult1c1, Sult1a2
Domain Architecture	No domain graphic available
Description	Sulfotransferase 1C1 (EC 2.8.2.-) (Phenol sulfotransferase).

E41L2_MOUSE
NC score	0.008466 (rank : 48)	θ value	8.99809 (rank : 52)
Query Neighborhood Hits	56	Target Neighborhood Hits	459	Shared Neighborhood Hits	17
SwissProt Accessions	O70318	Gene names	Epb41l2, Epb4.1l2
Domain Architecture
Description	Band 4.1-like protein 2 (Generally expressed protein 4.1) (4.1G).

NUCL_MOUSE
NC score	0.008169 (rank : 49)	θ value	8.99809 (rank : 55)
Query Neighborhood Hits	56	Target Neighborhood Hits	425	Shared Neighborhood Hits	13
SwissProt Accessions	P09405, Q548M9, Q61991, Q99K50	Gene names	Ncl, Nuc
Domain Architecture
Description	Nucleolin (Protein C23).

HCN2_MOUSE
NC score	0.006712 (rank : 50)	θ value	5.27518 (rank : 43)
Query Neighborhood Hits	56	Target Neighborhood Hits	278	Shared Neighborhood Hits	4
SwissProt Accessions	O88703, O70506	Gene names	Hcn2, Bcng2, Hac1
Domain Architecture
Description	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 (Brain cyclic nucleotide-gated channel 2) (BCNG-2) (Hyperpolarization-activated cation channel 1) (HAC-1).

TNIK_HUMAN
NC score	0.006224 (rank : 51)	θ value	1.06291 (rank : 19)
Query Neighborhood Hits	56	Target Neighborhood Hits	1570	Shared Neighborhood Hits	12
SwissProt Accessions	Q9UKE5, O60298, Q8WUY7, Q9UKD8, Q9UKD9, Q9UKE0, Q9UKE1, Q9UKE2, Q9UKE3, Q9UKE4	Gene names	TNIK, KIAA0551
Domain Architecture
Description	TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1).

TITIN_HUMAN
NC score	0.005263 (rank : 52)	θ value	2.36792 (rank : 29)
Query Neighborhood Hits	56	Target Neighborhood Hits	2923	Shared Neighborhood Hits	22
SwissProt Accessions	Q8WZ42, Q10465, Q10466, Q15598, Q2XUS3, Q32Q60, Q4U1Z6, Q6NSG0, Q6PDB1, Q6PJP0, Q7KYM2, Q7KYN4, Q7KYN5, Q7LDM3, Q7Z2X3, Q8TCG8, Q8WZ51, Q8WZ52, Q8WZ53, Q8WZB3, Q92761, Q92762, Q9UD97, Q9UP84, Q9Y6L9	Gene names	TTN
Domain Architecture	No domain graphic available
Description	Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS- 40.14).

SMUF2_HUMAN
NC score	0.004764 (rank : 53)	θ value	6.88961 (rank : 49)
Query Neighborhood Hits	56	Target Neighborhood Hits	142	Shared Neighborhood Hits	2
SwissProt Accessions	Q9HAU4, Q9H260	Gene names	SMURF2
Domain Architecture
Description	Smad ubiquitination regulatory factor 2 (EC 6.3.2.-) (Ubiquitin-- protein ligase SMURF2) (Smad-specific E3 ubiquitin ligase 2) (hSMURF2).

WNK2_HUMAN
NC score	0.003214 (rank : 54)	θ value	5.27518 (rank : 45)
Query Neighborhood Hits	56	Target Neighborhood Hits	1407	Shared Neighborhood Hits	12
SwissProt Accessions	Q9Y3S1, Q8IY36, Q9C0A3, Q9H3P4	Gene names	WNK2, KIAA1760, PRKWNK2
Domain Architecture
Description	Serine/threonine-protein kinase WNK2 (EC 2.7.11.1) (Protein kinase with no lysine 2) (Protein kinase, lysine-deficient 2).

MAST2_MOUSE
NC score	0.003046 (rank : 55)	θ value	2.36792 (rank : 27)
Query Neighborhood Hits	56	Target Neighborhood Hits	1110	Shared Neighborhood Hits	8
SwissProt Accessions	Q60592, Q6P9M1, Q8CHD1	Gene names	Mast2, Mast205
Domain Architecture	No domain graphic available
Description	Microtubule-associated serine/threonine-protein kinase 2 (EC 2.7.11.1).

SPTB2_MOUSE
NC score	0.002167 (rank : 56)	θ value	8.99809 (rank : 56)
Query Neighborhood Hits	56	Target Neighborhood Hits	770	Shared Neighborhood Hits	8
SwissProt Accessions	Q62261, Q5SQL8	Gene names	Sptbn1, Spnb-2, Spnb2, Sptb2
Domain Architecture
Description	Spectrin beta chain, brain 1 (Spectrin, non-erythroid beta chain 1) (Beta-II spectrin) (Fodrin beta chain).