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Network neighborhood for query Sequence : DPOE1_MOUSE

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DPOE1_MOUSE
SwissProt Accessions	Q9WVF7, Q9QX50	Gene names	Pole, Pole1
Domain Architecture
Description	DNA polymerase epsilon, catalytic subunit A (EC 2.7.7.7) (DNA polymerase II subunit A).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

DPOE1_HUMAN
θ value	0 (rank : 1)	NC score	0.994081 (rank : 2)
Query Neighborhood Hits	24	Target Neighborhood Hits	42	Shared Neighborhood Hits	16
SwissProt Accessions	Q07864, Q13533, Q86VH9	Gene names	POLE, POLE1
Domain Architecture
Description	DNA polymerase epsilon, catalytic subunit A (EC 2.7.7.7) (DNA polymerase II subunit A).

DPOE1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	24	Target Neighborhood Hits	24	Shared Neighborhood Hits	24
SwissProt Accessions	Q9WVF7, Q9QX50	Gene names	Pole, Pole1
Domain Architecture
Description	DNA polymerase epsilon, catalytic subunit A (EC 2.7.7.7) (DNA polymerase II subunit A).

DPOLA_HUMAN
θ value	0.000121331 (rank : 3)	NC score	0.207422 (rank : 3)
Query Neighborhood Hits	24	Target Neighborhood Hits	41	Shared Neighborhood Hits	7
SwissProt Accessions	P09884, Q86UQ7	Gene names	POLA1, POLA
Domain Architecture
Description	DNA polymerase alpha catalytic subunit (EC 2.7.7.7).

DPOLA_MOUSE
θ value	0.000270298 (rank : 4)	NC score	0.201230 (rank : 4)
Query Neighborhood Hits	24	Target Neighborhood Hits	56	Shared Neighborhood Hits	7
SwissProt Accessions	P33609	Gene names	Pola1, Pola
Domain Architecture
Description	DNA polymerase alpha catalytic subunit (EC 2.7.7.7).

TWF2_MOUSE
θ value	0.000786445 (rank : 5)	NC score	0.105742 (rank : 7)
Query Neighborhood Hits	24	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z0P5, Q3TD06, Q3TZG2, Q8BN77, Q9DCK8	Gene names	Ptk9l
Domain Architecture	No domain graphic available
Description	Twinfilin-2 (Twinfilin-1-like protein) (A6-related protein) (mA6RP).

TWF2_HUMAN
θ value	0.00509761 (rank : 6)	NC score	0.098551 (rank : 9)
Query Neighborhood Hits	24	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q6IBS0, Q9Y3F5	Gene names	PTK9L
Domain Architecture	No domain graphic available
Description	Twinfilin-2 (Twinfilin-1-like protein) (A6-related protein) (hA6RP) (Protein tyrosine kinase 9-like).

DPOD1_HUMAN
θ value	0.00665767 (rank : 7)	NC score	0.151735 (rank : 5)
Query Neighborhood Hits	24	Target Neighborhood Hits	28	Shared Neighborhood Hits	7
SwissProt Accessions	P28340, Q8NER3, Q96H98	Gene names	POLD1, POLD
Domain Architecture
Description	DNA polymerase delta catalytic subunit (EC 2.7.7.7) (DNA polymerase subunit delta p125).

CBP_MOUSE
θ value	0.21417 (rank : 8)	NC score	0.038101 (rank : 16)
Query Neighborhood Hits	24	Target Neighborhood Hits	1051	Shared Neighborhood Hits	3
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

DPOLZ_MOUSE
θ value	0.21417 (rank : 9)	NC score	0.098604 (rank : 8)
Query Neighborhood Hits	24	Target Neighborhood Hits	169	Shared Neighborhood Hits	7
SwissProt Accessions	Q61493, Q9JMD6, Q9QWX6	Gene names	Rev3l, Polz, Sez4
Domain Architecture
Description	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (Seizure-related protein 4).

DPOD1_MOUSE
θ value	0.47712 (rank : 10)	NC score	0.121299 (rank : 6)
Query Neighborhood Hits	24	Target Neighborhood Hits	19	Shared Neighborhood Hits	7
SwissProt Accessions	P52431, O54883	Gene names	Pold1
Domain Architecture
Description	DNA polymerase delta catalytic subunit (EC 2.7.7.7).

TREX1_HUMAN
θ value	1.38821 (rank : 11)	NC score	0.056621 (rank : 12)
Query Neighborhood Hits	24	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NSU2, Q8TEU2, Q9BPW1, Q9Y4X2	Gene names	TREX1
Domain Architecture
Description	Three prime repair exonuclease 1 (EC 3.1.11.2) (3'-5' exonuclease TREX1) (DNase III).

IPO11_HUMAN
θ value	1.81305 (rank : 12)	NC score	0.057543 (rank : 11)
Query Neighborhood Hits	24	Target Neighborhood Hits	32	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UI26, Q8N5R2, Q9NSJ6, Q9NVB1	Gene names	IPO11, RANBP11
Domain Architecture	No domain graphic available
Description	Importin-11 (Imp11) (Ran-binding protein 11) (RanBP11).

IPO11_MOUSE
θ value	3.0926 (rank : 13)	NC score	0.052595 (rank : 13)
Query Neighborhood Hits	24	Target Neighborhood Hits	32	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K2V6, Q8BU45, Q8K0B4	Gene names	Ipo11, Ranbp11
Domain Architecture	No domain graphic available
Description	Importin-11 (Imp11) (Ran-binding protein 11) (RanBP11).

PUM2_HUMAN
θ value	3.0926 (rank : 14)	NC score	0.033486 (rank : 18)
Query Neighborhood Hits	24	Target Neighborhood Hits	67	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TB72, O00234, Q53TV7, Q8WY43, Q9HAN2	Gene names	PUM2, KIAA0235, PUMH2
Domain Architecture
Description	Pumilio homolog 2 (Pumilio-2).

PUM2_MOUSE
θ value	3.0926 (rank : 15)	NC score	0.033526 (rank : 17)
Query Neighborhood Hits	24	Target Neighborhood Hits	65	Shared Neighborhood Hits	4
SwissProt Accessions	Q80U58, Q80UZ9, Q91YW4, Q925A0, Q9ERC7	Gene names	Pum2, Kiaa0235
Domain Architecture
Description	Pumilio homolog 2.

TNR16_MOUSE
θ value	3.0926 (rank : 16)	NC score	0.028759 (rank : 19)
Query Neighborhood Hits	24	Target Neighborhood Hits	178	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z0W1	Gene names	Ngfr, Tnfrsf16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Low affinity neurotrophin receptor p75NTR).

CI093_HUMAN
θ value	4.03905 (rank : 17)	NC score	0.005628 (rank : 26)
Query Neighborhood Hits	24	Target Neighborhood Hits	1088	Shared Neighborhood Hits	2
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

NKX61_HUMAN
θ value	4.03905 (rank : 18)	NC score	0.009239 (rank : 25)
Query Neighborhood Hits	24	Target Neighborhood Hits	431	Shared Neighborhood Hits	3
SwissProt Accessions	P78426	Gene names	NKX6-1, NKX6A
Domain Architecture
Description	Homeobox protein Nkx-6.1.

NKX61_MOUSE
θ value	4.03905 (rank : 19)	NC score	0.009342 (rank : 24)
Query Neighborhood Hits	24	Target Neighborhood Hits	439	Shared Neighborhood Hits	3
SwissProt Accessions	Q99MA9, Q9ERQ7	Gene names	Nkx6-1, Nkx6.1, Nkx6a
Domain Architecture
Description	Homeobox protein Nkx-6.1.

APLP1_MOUSE
θ value	5.27518 (rank : 20)	NC score	0.022943 (rank : 21)
Query Neighborhood Hits	24	Target Neighborhood Hits	130	Shared Neighborhood Hits	3
SwissProt Accessions	Q03157, Q8VC38	Gene names	Aplp1
Domain Architecture
Description	Amyloid-like protein 1 precursor (APLP) (APLP-1) [Contains: C30].

JUND_HUMAN
θ value	5.27518 (rank : 21)	NC score	0.023904 (rank : 20)
Query Neighborhood Hits	24	Target Neighborhood Hits	122	Shared Neighborhood Hits	3
SwissProt Accessions	P17535	Gene names	JUND
Domain Architecture
Description	Transcription factor jun-D.

KBTBA_HUMAN
θ value	6.88961 (rank : 22)	NC score	0.004764 (rank : 27)
Query Neighborhood Hits	24	Target Neighborhood Hits	184	Shared Neighborhood Hits	2
SwissProt Accessions	O60662	Gene names	KBTBD10, KRP1
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 10 (Kelch-related protein 1) (Kel-like protein 23) (Sarcosin).

P210L_HUMAN
θ value	6.88961 (rank : 23)	NC score	0.010686 (rank : 23)
Query Neighborhood Hits	24	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q5VU65, Q5T4L7, Q6ZRN1, Q6ZRT4, Q6ZU81, Q8NDI6	Gene names	NUP210L
Domain Architecture	No domain graphic available
Description	Nuclear pore membrane glycoprotein 210-like precursor (Nucleoporin 210 kDa-like).

TNR16_HUMAN
θ value	8.99809 (rank : 24)	NC score	0.015666 (rank : 22)
Query Neighborhood Hits	24	Target Neighborhood Hits	183	Shared Neighborhood Hits	3
SwissProt Accessions	P08138	Gene names	NGFR, TNFRSF16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Gp80-LNGFR) (p75 ICD) (Low affinity neurotrophin receptor p75NTR) (CD271 antigen).

DPOLZ_HUMAN
θ value	θ > 10 (rank : 25)	NC score	0.064109 (rank : 10)
Query Neighborhood Hits	24	Target Neighborhood Hits	200	Shared Neighborhood Hits	5
SwissProt Accessions	O60673, O43214	Gene names	REV3L, POLZ, REV3
Domain Architecture
Description	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (hREV3).

TWF1_HUMAN
θ value	θ > 10 (rank : 26)	NC score	0.050625 (rank : 15)
Query Neighborhood Hits	24	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q12792, Q59G07, Q5U0B1, Q6FHJ1, Q6FHL6, Q86XL6, Q8TCD3	Gene names	PTK9
Domain Architecture
Description	Twinfilin-1 (Protein A6) (Protein tyrosine kinase 9).

TWF1_MOUSE
θ value	θ > 10 (rank : 27)	NC score	0.051418 (rank : 14)
Query Neighborhood Hits	24	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	Q91YR1, O09132, Q52L77, Q80X09	Gene names	Ptk9
Domain Architecture
Description	Twinfilin-1 (Protein A6).

Hits sorted by NC score

DPOE1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	24	Target Neighborhood Hits	24	Shared Neighborhood Hits	24
SwissProt Accessions	Q9WVF7, Q9QX50	Gene names	Pole, Pole1
Domain Architecture
Description	DNA polymerase epsilon, catalytic subunit A (EC 2.7.7.7) (DNA polymerase II subunit A).

DPOE1_HUMAN
NC score	0.994081 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	24	Target Neighborhood Hits	42	Shared Neighborhood Hits	16
SwissProt Accessions	Q07864, Q13533, Q86VH9	Gene names	POLE, POLE1
Domain Architecture
Description	DNA polymerase epsilon, catalytic subunit A (EC 2.7.7.7) (DNA polymerase II subunit A).

DPOLA_HUMAN
NC score	0.207422 (rank : 3)	θ value	0.000121331 (rank : 3)
Query Neighborhood Hits	24	Target Neighborhood Hits	41	Shared Neighborhood Hits	7
SwissProt Accessions	P09884, Q86UQ7	Gene names	POLA1, POLA
Domain Architecture
Description	DNA polymerase alpha catalytic subunit (EC 2.7.7.7).

DPOLA_MOUSE
NC score	0.201230 (rank : 4)	θ value	0.000270298 (rank : 4)
Query Neighborhood Hits	24	Target Neighborhood Hits	56	Shared Neighborhood Hits	7
SwissProt Accessions	P33609	Gene names	Pola1, Pola
Domain Architecture
Description	DNA polymerase alpha catalytic subunit (EC 2.7.7.7).

DPOD1_HUMAN
NC score	0.151735 (rank : 5)	θ value	0.00665767 (rank : 7)
Query Neighborhood Hits	24	Target Neighborhood Hits	28	Shared Neighborhood Hits	7
SwissProt Accessions	P28340, Q8NER3, Q96H98	Gene names	POLD1, POLD
Domain Architecture
Description	DNA polymerase delta catalytic subunit (EC 2.7.7.7) (DNA polymerase subunit delta p125).

DPOD1_MOUSE
NC score	0.121299 (rank : 6)	θ value	0.47712 (rank : 10)
Query Neighborhood Hits	24	Target Neighborhood Hits	19	Shared Neighborhood Hits	7
SwissProt Accessions	P52431, O54883	Gene names	Pold1
Domain Architecture
Description	DNA polymerase delta catalytic subunit (EC 2.7.7.7).

TWF2_MOUSE
NC score	0.105742 (rank : 7)	θ value	0.000786445 (rank : 5)
Query Neighborhood Hits	24	Target Neighborhood Hits	30	Shared Neighborhood Hits	3
SwissProt Accessions	Q9Z0P5, Q3TD06, Q3TZG2, Q8BN77, Q9DCK8	Gene names	Ptk9l
Domain Architecture	No domain graphic available
Description	Twinfilin-2 (Twinfilin-1-like protein) (A6-related protein) (mA6RP).

DPOLZ_MOUSE
NC score	0.098604 (rank : 8)	θ value	0.21417 (rank : 9)
Query Neighborhood Hits	24	Target Neighborhood Hits	169	Shared Neighborhood Hits	7
SwissProt Accessions	Q61493, Q9JMD6, Q9QWX6	Gene names	Rev3l, Polz, Sez4
Domain Architecture
Description	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (Seizure-related protein 4).

TWF2_HUMAN
NC score	0.098551 (rank : 9)	θ value	0.00509761 (rank : 6)
Query Neighborhood Hits	24	Target Neighborhood Hits	24	Shared Neighborhood Hits	3
SwissProt Accessions	Q6IBS0, Q9Y3F5	Gene names	PTK9L
Domain Architecture	No domain graphic available
Description	Twinfilin-2 (Twinfilin-1-like protein) (A6-related protein) (hA6RP) (Protein tyrosine kinase 9-like).

DPOLZ_HUMAN
NC score	0.064109 (rank : 10)	θ value	θ > 10 (rank : 25)
Query Neighborhood Hits	24	Target Neighborhood Hits	200	Shared Neighborhood Hits	5
SwissProt Accessions	O60673, O43214	Gene names	REV3L, POLZ, REV3
Domain Architecture
Description	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (hREV3).

IPO11_HUMAN
NC score	0.057543 (rank : 11)	θ value	1.81305 (rank : 12)
Query Neighborhood Hits	24	Target Neighborhood Hits	32	Shared Neighborhood Hits	4
SwissProt Accessions	Q9UI26, Q8N5R2, Q9NSJ6, Q9NVB1	Gene names	IPO11, RANBP11
Domain Architecture	No domain graphic available
Description	Importin-11 (Imp11) (Ran-binding protein 11) (RanBP11).

TREX1_HUMAN
NC score	0.056621 (rank : 12)	θ value	1.38821 (rank : 11)
Query Neighborhood Hits	24	Target Neighborhood Hits	15	Shared Neighborhood Hits	3
SwissProt Accessions	Q9NSU2, Q8TEU2, Q9BPW1, Q9Y4X2	Gene names	TREX1
Domain Architecture
Description	Three prime repair exonuclease 1 (EC 3.1.11.2) (3'-5' exonuclease TREX1) (DNase III).

IPO11_MOUSE
NC score	0.052595 (rank : 13)	θ value	3.0926 (rank : 13)
Query Neighborhood Hits	24	Target Neighborhood Hits	32	Shared Neighborhood Hits	4
SwissProt Accessions	Q8K2V6, Q8BU45, Q8K0B4	Gene names	Ipo11, Ranbp11
Domain Architecture	No domain graphic available
Description	Importin-11 (Imp11) (Ran-binding protein 11) (RanBP11).

TWF1_MOUSE
NC score	0.051418 (rank : 14)	θ value	θ > 10 (rank : 27)
Query Neighborhood Hits	24	Target Neighborhood Hits	15	Shared Neighborhood Hits	2
SwissProt Accessions	Q91YR1, O09132, Q52L77, Q80X09	Gene names	Ptk9
Domain Architecture
Description	Twinfilin-1 (Protein A6).

TWF1_HUMAN
NC score	0.050625 (rank : 15)	θ value	θ > 10 (rank : 26)
Query Neighborhood Hits	24	Target Neighborhood Hits	16	Shared Neighborhood Hits	2
SwissProt Accessions	Q12792, Q59G07, Q5U0B1, Q6FHJ1, Q6FHL6, Q86XL6, Q8TCD3	Gene names	PTK9
Domain Architecture
Description	Twinfilin-1 (Protein A6) (Protein tyrosine kinase 9).

CBP_MOUSE
NC score	0.038101 (rank : 16)	θ value	0.21417 (rank : 8)
Query Neighborhood Hits	24	Target Neighborhood Hits	1051	Shared Neighborhood Hits	3
SwissProt Accessions	P45481	Gene names	Crebbp, Cbp
Domain Architecture
Description	CREB-binding protein (EC 2.3.1.48).

PUM2_MOUSE
NC score	0.033526 (rank : 17)	θ value	3.0926 (rank : 15)
Query Neighborhood Hits	24	Target Neighborhood Hits	65	Shared Neighborhood Hits	4
SwissProt Accessions	Q80U58, Q80UZ9, Q91YW4, Q925A0, Q9ERC7	Gene names	Pum2, Kiaa0235
Domain Architecture
Description	Pumilio homolog 2.

PUM2_HUMAN
NC score	0.033486 (rank : 18)	θ value	3.0926 (rank : 14)
Query Neighborhood Hits	24	Target Neighborhood Hits	67	Shared Neighborhood Hits	4
SwissProt Accessions	Q8TB72, O00234, Q53TV7, Q8WY43, Q9HAN2	Gene names	PUM2, KIAA0235, PUMH2
Domain Architecture
Description	Pumilio homolog 2 (Pumilio-2).

TNR16_MOUSE
NC score	0.028759 (rank : 19)	θ value	3.0926 (rank : 16)
Query Neighborhood Hits	24	Target Neighborhood Hits	178	Shared Neighborhood Hits	4
SwissProt Accessions	Q9Z0W1	Gene names	Ngfr, Tnfrsf16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Low affinity neurotrophin receptor p75NTR).

JUND_HUMAN
NC score	0.023904 (rank : 20)	θ value	5.27518 (rank : 21)
Query Neighborhood Hits	24	Target Neighborhood Hits	122	Shared Neighborhood Hits	3
SwissProt Accessions	P17535	Gene names	JUND
Domain Architecture
Description	Transcription factor jun-D.

APLP1_MOUSE
NC score	0.022943 (rank : 21)	θ value	5.27518 (rank : 20)
Query Neighborhood Hits	24	Target Neighborhood Hits	130	Shared Neighborhood Hits	3
SwissProt Accessions	Q03157, Q8VC38	Gene names	Aplp1
Domain Architecture
Description	Amyloid-like protein 1 precursor (APLP) (APLP-1) [Contains: C30].

TNR16_HUMAN
NC score	0.015666 (rank : 22)	θ value	8.99809 (rank : 24)
Query Neighborhood Hits	24	Target Neighborhood Hits	183	Shared Neighborhood Hits	3
SwissProt Accessions	P08138	Gene names	NGFR, TNFRSF16
Domain Architecture
Description	Tumor necrosis factor receptor superfamily member 16 precursor (Low- affinity nerve growth factor receptor) (NGF receptor) (Gp80-LNGFR) (p75 ICD) (Low affinity neurotrophin receptor p75NTR) (CD271 antigen).

P210L_HUMAN
NC score	0.010686 (rank : 23)	θ value	6.88961 (rank : 23)
Query Neighborhood Hits	24	Target Neighborhood Hits	21	Shared Neighborhood Hits	2
SwissProt Accessions	Q5VU65, Q5T4L7, Q6ZRN1, Q6ZRT4, Q6ZU81, Q8NDI6	Gene names	NUP210L
Domain Architecture	No domain graphic available
Description	Nuclear pore membrane glycoprotein 210-like precursor (Nucleoporin 210 kDa-like).

NKX61_MOUSE
NC score	0.009342 (rank : 24)	θ value	4.03905 (rank : 19)
Query Neighborhood Hits	24	Target Neighborhood Hits	439	Shared Neighborhood Hits	3
SwissProt Accessions	Q99MA9, Q9ERQ7	Gene names	Nkx6-1, Nkx6.1, Nkx6a
Domain Architecture
Description	Homeobox protein Nkx-6.1.

NKX61_HUMAN
NC score	0.009239 (rank : 25)	θ value	4.03905 (rank : 18)
Query Neighborhood Hits	24	Target Neighborhood Hits	431	Shared Neighborhood Hits	3
SwissProt Accessions	P78426	Gene names	NKX6-1, NKX6A
Domain Architecture
Description	Homeobox protein Nkx-6.1.

CI093_HUMAN
NC score	0.005628 (rank : 26)	θ value	4.03905 (rank : 17)
Query Neighborhood Hits	24	Target Neighborhood Hits	1088	Shared Neighborhood Hits	2
SwissProt Accessions	Q6TFL3, Q5SU58, Q6P1W1, Q6ZR13, Q8N1Z4, Q8N8L3, Q8TBR2	Gene names	C9orf93
Domain Architecture	No domain graphic available
Description	Uncharacterized protein C9orf93.

KBTBA_HUMAN
NC score	0.004764 (rank : 27)	θ value	6.88961 (rank : 22)
Query Neighborhood Hits	24	Target Neighborhood Hits	184	Shared Neighborhood Hits	2
SwissProt Accessions	O60662	Gene names	KBTBD10, KRP1
Domain Architecture
Description	Kelch repeat and BTB domain-containing protein 10 (Kelch-related protein 1) (Kel-like protein 23) (Sarcosin).