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Network neighborhood for query Sequence : DPOD1_MOUSE

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DPOD1_MOUSE
SwissProt Accessions	P52431, O54883	Gene names	Pold1
Domain Architecture
Description	DNA polymerase delta catalytic subunit (EC 2.7.7.7).
Rank Plots	Jump to hits sorted by θ Jump to hits sorted by NC score

Hits sorted by θ

DPOD1_HUMAN
θ value	0 (rank : 1)	NC score	0.997062 (rank : 2)
Query Neighborhood Hits	19	Target Neighborhood Hits	28	Shared Neighborhood Hits	14
SwissProt Accessions	P28340, Q8NER3, Q96H98	Gene names	POLD1, POLD
Domain Architecture
Description	DNA polymerase delta catalytic subunit (EC 2.7.7.7) (DNA polymerase subunit delta p125).

DPOD1_MOUSE
θ value	0 (rank : 2)	NC score	0.999962 (rank : 1)
Query Neighborhood Hits	19	Target Neighborhood Hits	19	Shared Neighborhood Hits	19
SwissProt Accessions	P52431, O54883	Gene names	Pold1
Domain Architecture
Description	DNA polymerase delta catalytic subunit (EC 2.7.7.7).

DPOLZ_MOUSE
θ value	5.6855e-87 (rank : 3)	NC score	0.808349 (rank : 3)
Query Neighborhood Hits	19	Target Neighborhood Hits	169	Shared Neighborhood Hits	8
SwissProt Accessions	Q61493, Q9JMD6, Q9QWX6	Gene names	Rev3l, Polz, Sez4
Domain Architecture
Description	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (Seizure-related protein 4).

DPOLZ_HUMAN
θ value	2.64101e-84 (rank : 4)	NC score	0.804768 (rank : 4)
Query Neighborhood Hits	19	Target Neighborhood Hits	200	Shared Neighborhood Hits	6
SwissProt Accessions	O60673, O43214	Gene names	REV3L, POLZ, REV3
Domain Architecture
Description	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (hREV3).

DPOLA_HUMAN
θ value	2.94719e-51 (rank : 5)	NC score	0.763306 (rank : 5)
Query Neighborhood Hits	19	Target Neighborhood Hits	41	Shared Neighborhood Hits	8
SwissProt Accessions	P09884, Q86UQ7	Gene names	POLA1, POLA
Domain Architecture
Description	DNA polymerase alpha catalytic subunit (EC 2.7.7.7).

DPOLA_MOUSE
θ value	3.60269e-49 (rank : 6)	NC score	0.758246 (rank : 6)
Query Neighborhood Hits	19	Target Neighborhood Hits	56	Shared Neighborhood Hits	8
SwissProt Accessions	P33609	Gene names	Pola1, Pola
Domain Architecture
Description	DNA polymerase alpha catalytic subunit (EC 2.7.7.7).

DPOE1_MOUSE
θ value	0.47712 (rank : 7)	NC score	0.121299 (rank : 7)
Query Neighborhood Hits	19	Target Neighborhood Hits	24	Shared Neighborhood Hits	7
SwissProt Accessions	Q9WVF7, Q9QX50	Gene names	Pole, Pole1
Domain Architecture
Description	DNA polymerase epsilon, catalytic subunit A (EC 2.7.7.7) (DNA polymerase II subunit A).

DPOE1_HUMAN
θ value	0.813845 (rank : 8)	NC score	0.120896 (rank : 8)
Query Neighborhood Hits	19	Target Neighborhood Hits	42	Shared Neighborhood Hits	7
SwissProt Accessions	Q07864, Q13533, Q86VH9	Gene names	POLE, POLE1
Domain Architecture
Description	DNA polymerase epsilon, catalytic subunit A (EC 2.7.7.7) (DNA polymerase II subunit A).

PDIA4_HUMAN
θ value	1.38821 (rank : 9)	NC score	0.026089 (rank : 11)
Query Neighborhood Hits	19	Target Neighborhood Hits	60	Shared Neighborhood Hits	4
SwissProt Accessions	P13667	Gene names	PDIA4, ERP70, ERP72
Domain Architecture
Description	Protein disulfide-isomerase A4 precursor (EC 5.3.4.1) (Protein ERp-72) (ERp72).

CMC2_HUMAN
θ value	1.81305 (rank : 10)	NC score	0.011767 (rank : 15)
Query Neighborhood Hits	19	Target Neighborhood Hits	93	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UJS0, O14566, O14575, Q9NZW1, Q9UNI7	Gene names	SLC25A13, ARALAR2
Domain Architecture
Description	Calcium-binding mitochondrial carrier protein Aralar2 (Mitochondrial aspartate glutamate carrier 2) (Solute carrier family 25 member 13) (Citrin).

PEX26_MOUSE
θ value	1.81305 (rank : 11)	NC score	0.044667 (rank : 10)
Query Neighborhood Hits	19	Target Neighborhood Hits	4	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BGI5, Q3UGH5, Q9D661	Gene names	Pex26
Domain Architecture
Description	Peroxisome assembly protein 26 (Peroxin-26).

LUZP1_HUMAN
θ value	2.36792 (rank : 12)	NC score	0.016258 (rank : 13)
Query Neighborhood Hits	19	Target Neighborhood Hits	739	Shared Neighborhood Hits	4
SwissProt Accessions	Q86V48, Q5TH93, Q8N4X3, Q8TEH1	Gene names	LUZP1
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1.

PTPRS_HUMAN
θ value	3.0926 (rank : 13)	NC score	0.003637 (rank : 20)
Query Neighborhood Hits	19	Target Neighborhood Hits	472	Shared Neighborhood Hits	2
SwissProt Accessions	Q13332, O75255, O75870, Q15718, Q16341	Gene names	PTPRS
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase S precursor (EC 3.1.3.48) (R-PTP-S) (Protein-tyrosine phosphatase sigma) (R-PTP-sigma).

IGSF8_MOUSE
θ value	5.27518 (rank : 14)	NC score	0.013101 (rank : 14)
Query Neighborhood Hits	19	Target Neighborhood Hits	94	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R366, Q8R0L7	Gene names	Igsf8, Ewi2, Kct4, Pgrl
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 8 precursor (CD81 partner 3) (Glu- Trp-Ile EWI motif-containing protein 2) (EWI-2) (Keratinocytes- associated transmembrane protein 4) (KCT-4) (Prostaglandin regulatory- like protein) (CD316 antigen).

PDIA4_MOUSE
θ value	5.27518 (rank : 15)	NC score	0.019935 (rank : 12)
Query Neighborhood Hits	19	Target Neighborhood Hits	57	Shared Neighborhood Hits	4
SwissProt Accessions	P08003, P15841	Gene names	Pdia4, Cai, Erp72
Domain Architecture
Description	Protein disulfide-isomerase A4 precursor (EC 5.3.4.1) (Protein ERp-72) (ERp72).

FLIP1_MOUSE
θ value	8.99809 (rank : 16)	NC score	0.005431 (rank : 18)
Query Neighborhood Hits	19	Target Neighborhood Hits	1176	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CS72	Gene names	Filip1
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

MASP2_MOUSE
θ value	8.99809 (rank : 17)	NC score	0.004272 (rank : 19)
Query Neighborhood Hits	19	Target Neighborhood Hits	382	Shared Neighborhood Hits	3
SwissProt Accessions	Q91WP0, Q9QXA4, Q9QXD2, Q9QXD5, Q9Z338	Gene names	Masp2
Domain Architecture	No domain graphic available
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

SNIP_HUMAN
θ value	8.99809 (rank : 18)	NC score	0.009279 (rank : 16)
Query Neighborhood Hits	19	Target Neighborhood Hits	313	Shared Neighborhood Hits	2
SwissProt Accessions	Q9C0H9, Q8N4W8	Gene names	P140, KIAA1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

TP53B_HUMAN
θ value	8.99809 (rank : 19)	NC score	0.008230 (rank : 17)
Query Neighborhood Hits	19	Target Neighborhood Hits	413	Shared Neighborhood Hits	2
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

SGP50_MOUSE
θ value	θ > 10 (rank : 20)	NC score	0.051654 (rank : 9)
Query Neighborhood Hits	19	Target Neighborhood Hits	15	Shared Neighborhood Hits	1
SwissProt Accessions	Q02596	Gene names	Glycam1
Domain Architecture
Description	Sulfated 50 kDa glycoprotein precursor (SGP50) (Endothelial ligand FOR L-selectin) (Glycosylation-dependent cell adhesion molecule 1) (GlyCAM-1) (MC26).

Hits sorted by NC score

DPOD1_MOUSE
NC score	0.999962 (rank : 1)	θ value	0 (rank : 2)
Query Neighborhood Hits	19	Target Neighborhood Hits	19	Shared Neighborhood Hits	19
SwissProt Accessions	P52431, O54883	Gene names	Pold1
Domain Architecture
Description	DNA polymerase delta catalytic subunit (EC 2.7.7.7).

DPOD1_HUMAN
NC score	0.997062 (rank : 2)	θ value	0 (rank : 1)
Query Neighborhood Hits	19	Target Neighborhood Hits	28	Shared Neighborhood Hits	14
SwissProt Accessions	P28340, Q8NER3, Q96H98	Gene names	POLD1, POLD
Domain Architecture
Description	DNA polymerase delta catalytic subunit (EC 2.7.7.7) (DNA polymerase subunit delta p125).

DPOLZ_MOUSE
NC score	0.808349 (rank : 3)	θ value	5.6855e-87 (rank : 3)
Query Neighborhood Hits	19	Target Neighborhood Hits	169	Shared Neighborhood Hits	8
SwissProt Accessions	Q61493, Q9JMD6, Q9QWX6	Gene names	Rev3l, Polz, Sez4
Domain Architecture
Description	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (Seizure-related protein 4).

DPOLZ_HUMAN
NC score	0.804768 (rank : 4)	θ value	2.64101e-84 (rank : 4)
Query Neighborhood Hits	19	Target Neighborhood Hits	200	Shared Neighborhood Hits	6
SwissProt Accessions	O60673, O43214	Gene names	REV3L, POLZ, REV3
Domain Architecture
Description	DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (hREV3).

DPOLA_HUMAN
NC score	0.763306 (rank : 5)	θ value	2.94719e-51 (rank : 5)
Query Neighborhood Hits	19	Target Neighborhood Hits	41	Shared Neighborhood Hits	8
SwissProt Accessions	P09884, Q86UQ7	Gene names	POLA1, POLA
Domain Architecture
Description	DNA polymerase alpha catalytic subunit (EC 2.7.7.7).

DPOLA_MOUSE
NC score	0.758246 (rank : 6)	θ value	3.60269e-49 (rank : 6)
Query Neighborhood Hits	19	Target Neighborhood Hits	56	Shared Neighborhood Hits	8
SwissProt Accessions	P33609	Gene names	Pola1, Pola
Domain Architecture
Description	DNA polymerase alpha catalytic subunit (EC 2.7.7.7).

DPOE1_MOUSE
NC score	0.121299 (rank : 7)	θ value	0.47712 (rank : 7)
Query Neighborhood Hits	19	Target Neighborhood Hits	24	Shared Neighborhood Hits	7
SwissProt Accessions	Q9WVF7, Q9QX50	Gene names	Pole, Pole1
Domain Architecture
Description	DNA polymerase epsilon, catalytic subunit A (EC 2.7.7.7) (DNA polymerase II subunit A).

DPOE1_HUMAN
NC score	0.120896 (rank : 8)	θ value	0.813845 (rank : 8)
Query Neighborhood Hits	19	Target Neighborhood Hits	42	Shared Neighborhood Hits	7
SwissProt Accessions	Q07864, Q13533, Q86VH9	Gene names	POLE, POLE1
Domain Architecture
Description	DNA polymerase epsilon, catalytic subunit A (EC 2.7.7.7) (DNA polymerase II subunit A).

SGP50_MOUSE
NC score	0.051654 (rank : 9)	θ value	θ > 10 (rank : 20)
Query Neighborhood Hits	19	Target Neighborhood Hits	15	Shared Neighborhood Hits	1
SwissProt Accessions	Q02596	Gene names	Glycam1
Domain Architecture
Description	Sulfated 50 kDa glycoprotein precursor (SGP50) (Endothelial ligand FOR L-selectin) (Glycosylation-dependent cell adhesion molecule 1) (GlyCAM-1) (MC26).

PEX26_MOUSE
NC score	0.044667 (rank : 10)	θ value	1.81305 (rank : 11)
Query Neighborhood Hits	19	Target Neighborhood Hits	4	Shared Neighborhood Hits	3
SwissProt Accessions	Q8BGI5, Q3UGH5, Q9D661	Gene names	Pex26
Domain Architecture
Description	Peroxisome assembly protein 26 (Peroxin-26).

PDIA4_HUMAN
NC score	0.026089 (rank : 11)	θ value	1.38821 (rank : 9)
Query Neighborhood Hits	19	Target Neighborhood Hits	60	Shared Neighborhood Hits	4
SwissProt Accessions	P13667	Gene names	PDIA4, ERP70, ERP72
Domain Architecture
Description	Protein disulfide-isomerase A4 precursor (EC 5.3.4.1) (Protein ERp-72) (ERp72).

PDIA4_MOUSE
NC score	0.019935 (rank : 12)	θ value	5.27518 (rank : 15)
Query Neighborhood Hits	19	Target Neighborhood Hits	57	Shared Neighborhood Hits	4
SwissProt Accessions	P08003, P15841	Gene names	Pdia4, Cai, Erp72
Domain Architecture
Description	Protein disulfide-isomerase A4 precursor (EC 5.3.4.1) (Protein ERp-72) (ERp72).

LUZP1_HUMAN
NC score	0.016258 (rank : 13)	θ value	2.36792 (rank : 12)
Query Neighborhood Hits	19	Target Neighborhood Hits	739	Shared Neighborhood Hits	4
SwissProt Accessions	Q86V48, Q5TH93, Q8N4X3, Q8TEH1	Gene names	LUZP1
Domain Architecture	No domain graphic available
Description	Leucine zipper protein 1.

IGSF8_MOUSE
NC score	0.013101 (rank : 14)	θ value	5.27518 (rank : 14)
Query Neighborhood Hits	19	Target Neighborhood Hits	94	Shared Neighborhood Hits	2
SwissProt Accessions	Q8R366, Q8R0L7	Gene names	Igsf8, Ewi2, Kct4, Pgrl
Domain Architecture	No domain graphic available
Description	Immunoglobulin superfamily member 8 precursor (CD81 partner 3) (Glu- Trp-Ile EWI motif-containing protein 2) (EWI-2) (Keratinocytes- associated transmembrane protein 4) (KCT-4) (Prostaglandin regulatory- like protein) (CD316 antigen).

CMC2_HUMAN
NC score	0.011767 (rank : 15)	θ value	1.81305 (rank : 10)
Query Neighborhood Hits	19	Target Neighborhood Hits	93	Shared Neighborhood Hits	2
SwissProt Accessions	Q9UJS0, O14566, O14575, Q9NZW1, Q9UNI7	Gene names	SLC25A13, ARALAR2
Domain Architecture
Description	Calcium-binding mitochondrial carrier protein Aralar2 (Mitochondrial aspartate glutamate carrier 2) (Solute carrier family 25 member 13) (Citrin).

SNIP_HUMAN
NC score	0.009279 (rank : 16)	θ value	8.99809 (rank : 18)
Query Neighborhood Hits	19	Target Neighborhood Hits	313	Shared Neighborhood Hits	2
SwissProt Accessions	Q9C0H9, Q8N4W8	Gene names	P140, KIAA1684
Domain Architecture	No domain graphic available
Description	p130Cas-associated protein (p140Cap) (SNAP-25-interacting protein) (SNIP).

TP53B_HUMAN
NC score	0.008230 (rank : 17)	θ value	8.99809 (rank : 19)
Query Neighborhood Hits	19	Target Neighborhood Hits	413	Shared Neighborhood Hits	2
SwissProt Accessions	Q12888, Q2M1Z7, Q4LE46, Q5FWZ3, Q7Z3U4	Gene names	TP53BP1
Domain Architecture
Description	Tumor suppressor p53-binding protein 1 (p53-binding protein 1) (p53BP1) (53BP1).

FLIP1_MOUSE
NC score	0.005431 (rank : 18)	θ value	8.99809 (rank : 16)
Query Neighborhood Hits	19	Target Neighborhood Hits	1176	Shared Neighborhood Hits	4
SwissProt Accessions	Q9CS72	Gene names	Filip1
Domain Architecture	No domain graphic available
Description	Filamin-A-interacting protein 1 (FILIP).

MASP2_MOUSE
NC score	0.004272 (rank : 19)	θ value	8.99809 (rank : 17)
Query Neighborhood Hits	19	Target Neighborhood Hits	382	Shared Neighborhood Hits	3
SwissProt Accessions	Q91WP0, Q9QXA4, Q9QXD2, Q9QXD5, Q9Z338	Gene names	Masp2
Domain Architecture	No domain graphic available
Description	Mannan-binding lectin serine protease 2 precursor (EC 3.4.21.104) (Mannose-binding protein-associated serine protease 2) (MASP-2) (MBL- associated serine protease 2) [Contains: Mannan-binding lectin serine protease 2 A chain; Mannan-binding lectin serine protease 2 B chain].

PTPRS_HUMAN
NC score	0.003637 (rank : 20)	θ value	3.0926 (rank : 13)
Query Neighborhood Hits	19	Target Neighborhood Hits	472	Shared Neighborhood Hits	2
SwissProt Accessions	Q13332, O75255, O75870, Q15718, Q16341	Gene names	PTPRS
Domain Architecture
Description	Receptor-type tyrosine-protein phosphatase S precursor (EC 3.1.3.48) (R-PTP-S) (Protein-tyrosine phosphatase sigma) (R-PTP-sigma).